Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACAA2 | ACAA2 | P42765 | 3-ketoacyl-CoA thiolase, mitochondrial | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 42 | 51 | 2 | 2 | 0 |
| ACADM_ENST00000370841 | ACADM | P11310 | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 61 | 41 | 5 | 5 | 19 |
| ACAT2 | ACAT2 | Q9BWD1 | Acetyl-CoA acetyltransferase, cytosolic | chr6 | Not Cancer Driver | No | 1 | hippie | 36 | 47 | 4 | 4 | 0 |
| ADPRM | ADPRM | Q3LIE5 | Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase | chr17 | Not Cancer Driver | No | 1 | biogrid | 38 | 32 | 4 | 4 | 0 |
| AGR2 | AGR2 | O95994 | Anterior gradient protein 2 homolog | chr7 | Not Cancer Driver | No | 1 | hippie | 23 | 20 | 2 | 2 | 0 |
| AHCY | AHCY | P23526 | Adenosylhomocysteinase | chr20 | Not Cancer Driver | No | 1 | hippie | 58 | 0 | 0 | 0 | 4 |
| AIFM1 | AIFM1 | O95831 | Apoptosis-inducing factor 1, mitochondrial | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 88 | 166 | 22 | 22 | 11 |
| ALDH1B1 | ALDH1B1 | P30837 | Aldehyde dehydrogenase X, mitochondrial | chr9 | Not Cancer Driver | No | 2 | hippie, biogrid | 94 | 54 | 11 | 11 | 0 |
| ALDH2 | ALDH2 | P05091 | Aldehyde dehydrogenase, mitochondrial | chr12 | Census | Yes | 1 | hippie, biogrid | 60 | 44 | 1 | 1 | 0 |
| ALDH5A1_ENST00000357578 | ALDH5A1 | P51649 | Succinate-semialdehyde dehydrogenase, mitochondrial | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 64 | 31 | 7 | 7 | 12 |
| ALDH9A1 | ALDH9A1 | P49189 | 4-trimethylaminobutyraldehyde dehydrogenase | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 57 | 16 | 0 | 0 | 0 |
| ALDOA_ENST00000643777 | ALDOA | P04075 | Fructose-bisphosphate aldolase A | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 47 | 65 | 9 | 9 | 3 |
| ALDOC_ENST00000395321 | ALDOC | P09972 | Fructose-bisphosphate aldolase C | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 79 | 4 | 4 | 0 |
| ANXA11 | ANXA11 | P50995 | Annexin A11 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 63 | 244 | 31 | 31 | 1 |
| APBB1 | APBB1 | O00213 | Amyloid beta precursor protein binding family B member 1 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 105 | 399 | 58 | 58 | 0 |
| ASB6 | ASB6 | Q9NWX5 | Ankyrin repeat and SOCS box protein 6 | chr9 | Not Cancer Driver | No | 1 | hippie | 35 | 31 | 3 | 3 | 0 |
| ASS1_ENST00000352480 | ASS1 | P00966 | Argininosuccinate synthase | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 65 | 63 | 8 | 8 | 86 |
| ATF2 | ATF2 | P15336 | Cyclic AMP-dependent transcription factor ATF-2 | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 65 | 451 | 58 | 58 | 0 |
| ATIC | ATIC | P31939 | Bifunctional purine biosynthesis protein ATIC | chr2 | Census | Yes | 2 | hippie, biogrid | 74 | 25 | 1 | 1 | 1 |
| ATPAF1_ENST00000574428 | ATPAF1 | Q5TC12 | ATP synthase mitochondrial F1 complex assembly factor 1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 33 | 47 | 8 | 8 | 0 |
| BIRC3_ENST00000532808 | BIRC3 | Q13489 | Baculoviral IAP repeat-containing protein 3 | chr11 | Census, Compendium | Yes | 1 | hippie | 77 | 98 | 16 | 16 | 0 |
| C11orf49_ENST00000278460 | CSTPP1 | Q9H6J7 | Centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | chr11 | Not Cancer Driver | No | 1 | intact | 26 | 101 | 9 | 9 | 0 |
| C11orf54_ENST00000354421 | C11orf54 | Q9H0W9 | Ester hydrolase C11orf54 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 23 | 0 | 0 | 0 |
| C9orf64 | C9orf64 | Q5T6V5 | Queuosine salvage protein | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 1 | 0 | 0 | 0 |
| CAB39 | CAB39 | Q9Y376 | Calcium-binding protein 39 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 43 | 5 | 5 | 0 |
| CALD1 | CALD1 | Q05682 | Caldesmon | chr7 | Not Cancer Driver | No | 1 | hippie | 133 | 793 | 133 | 133 | 0 |
| CAPNS1 | CAPNS1 | P04632 | Calpain small subunit 1 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 30 | 58 | 5 | 5 | 0 |
| CARS2 | CARS2 | Q9HA77 | Probable cysteine--tRNA ligase, mitochondrial | chr13 | Not Cancer Driver | No | 1 | biogrid | 51 | 87 | 8 | 8 | 1 |
| CBR1 | CBR1 | P16152 | Carbonyl reductase [NADPH] 1 | chr21 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 62 | 11 | 11 | 0 |
| CCDC102B | CCDC102B | Q68D86 | Coiled-coil domain-containing protein 102B | chr18 | Not Cancer Driver | No | 1 | hippie | 133 | 334 | 89 | 89 | 0 |
| CCDC57_ENST00000392347 | CCDC57 | Q2TAC2 | Coiled-coil domain-containing protein 57 | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 107 | 595 | 65 | 65 | 0 |
| CCNDBP1 | CCNDBP1 | O95273 | Cyclin-D1-binding protein 1 | chr15 | Not Cancer Driver | No | 1 | hippie | 35 | 63 | 5 | 5 | 0 |
| CDK2 | CDK2 | P24941 | Cyclin-dependent kinase 2 | chr12 | Not Cancer Driver | No | 1 | hippie | 24 | 0 | 0 | 0 | 0 |
| CLUAP1_ENST00000576634 | CLUAP1 | Q96AJ1 | Clusterin-associated protein 1 | chr16 | Not Cancer Driver | No | 1 | hippie | 48 | 203 | 22 | 22 | 0 |
| CMPK1 | CMPK1 | P30085-3 | Isoform 3 of UMP-CMP kinase | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 30 | 3 | 3 | 0 |
| COPE_ENST00000262812 | COPE | O14579 | Coatomer subunit epsilon | chr19 | Not Cancer Driver | No | 1 | biogrid | 29 | 47 | 6 | 6 | 0 |
| COQ2_ENST00000647002 | COQ2 | Q96H96 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial | chr4 | Not Cancer Driver | No | 1 | biogrid | 23 | 25 | 0 | 0 | 17 |
| COX16 | COX16 | Q9P0S2 | Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial | chr14 | Not Cancer Driver | No | 1 | biogrid | 13 | 39 | 6 | 6 | 0 |
| COX6C_ENST00000522940 | COX6C | P09669 | Cytochrome c oxidase subunit 6C | chr8 | Census | Yes | 1 | biogrid | 14 | 0 | 0 | 0 | 0 |
| CPOX | CPOX | P36551 | Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 49 | 126 | 7 | 7 | 17 |
| CPS1_ENST00000233072 | CPS1 | P31327 | Carbamoyl-phosphate synthase [ammonia], mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 368 | 73 | 22 | 22 | 140 |
| CRIP1_ENST00000409393 | CRIP1 | P50238 | Cysteine-rich protein 1 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 6 | 8 | 1 | 1 | 0 |
| DAZAP1 | DAZAP1 | Q96EP5 | DAZ-associated protein 1 | chr19 | Compendium | Yes | 1 | hippie, biogrid | 53 | 327 | 45 | 45 | 0 |
| DBT | DBT | P11182 | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 64 | 81 | 11 | 11 | 3 |
| DGCR6 | DGCR6 | Q14129 | Protein DGCR6 | chr22 | Not Cancer Driver | No | 1 | intact, hippie | 27 | 60 | 9 | 9 | 0 |
| DHX15 | DHX15 | O43143 | ATP-dependent RNA helicase DHX15 | chr4 | Not Cancer Driver | No | 1 | hippie | 110 | 180 | 30 | 30 | 0 |
| DIABLO | DIABLO | Q9NR28 | Diablo IAP-binding mitochondrial protein | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 62 | 54 | 8 | 8 | 1 |
| DLD | DLD | P09622 | Dihydrolipoyl dehydrogenase, mitochondrial | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 17 | 0 | 0 | 10 |
| ECHS1 | ECHS1 | P30084 | Enoyl-CoA hydratase, mitochondrial | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 7 | 1 | 1 | 14 |
| EIF6_ENST00000374436 | EIF6 | P56537 | Eukaryotic translation initiation factor 6 | chr20 | Not Cancer Driver | No | 1 | intact, hippie | 30 | 17 | 3 | 3 | 0 |
| ENO1 | ENO1 | P06733 | Alpha-enolase | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 21 | 2 | 2 | 0 |
| ETHE1 | ETHE1 | O95571 | Persulfide dioxygenase ETHE1, mitochondrial | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 21 | 6 | 0 | 0 | 9 |
| EXOSC5 | EXOSC5 | Q9NQT4 | Exosome complex component RRP46 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 43 | 31 | 3 | 3 | 0 |
| EZR | EZR | P15311 | Ezrin | chr6 | Census | Yes | 1 | hippie | 66 | 295 | 35 | 35 | 0 |
| FAHD2A | FAHD2A | Q96GK7 | Fumarylacetoacetate hydrolase domain-containing protein 2A | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 39 | 8 | 2 | 2 | 0 |
| FDXR_ENST00000293195 | FDXR | P22570 | NADPH:adrenodoxin oxidoreductase, mitochondrial | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 68 | 102 | 14 | 14 | 4 |
| FGD5 | FGD5 | Q6ZNL6 | FYVE, RhoGEF and PH domain-containing protein 5 | chr3 | Compendium | Yes | 1 | hippie, biogrid | 275 | 915 | 180 | 180 | 0 |
| GATB | GATB | O75879 | Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial | chr4 | Not Cancer Driver | No | 1 | biogrid | 79 | 138 | 26 | 26 | 0 |
| GDI2 | GDI2 | P50395 | Rab GDP dissociation inhibitor beta | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 49 | 23 | 2 | 2 | 0 |
| GLOD4_ENST00000301328 | GLOD4 | Q9HC38 | Glyoxalase domain-containing protein 4 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 44 | 3 | 3 | 0 |
| GNPDA1_ENST00000311337 | GNPDA1 | P46926 | Glucosamine-6-phosphate isomerase 1 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 17 | 3 | 3 | 0 |
| GNPDA2 | GNPDA2 | Q8TDQ7 | Glucosamine-6-phosphate isomerase 2 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 32 | 0 | 0 | 0 | 0 |
| GNPNAT1 | GNPNAT1 | Q96EK6 | Glucosamine 6-phosphate N-acetyltransferase | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 19 | 24 | 5 | 5 | 0 |
| GOT1 | GOT1 | P17174 | Aspartate aminotransferase, cytoplasmic | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 56 | 35 | 5 | 5 | 0 |
| GPD1 | GPD1 | P21695 | Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 59 | 2 | 0 | 0 | 1 |
| GPD1L | GPD1L | Q8N335 | Glycerol-3-phosphate dehydrogenase 1-like protein | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 40 | 13 | 1 | 1 | 0 |
| GPI_ENST00000644934 | GPI | P06744 | Glucose-6-phosphate isomerase | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 77 | 73 | 11 | 11 | 24 |
| GRB2_ENST00000392564 | GRB2 | P62993 | Growth factor receptor-bound protein 2 | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 28 | 10 | 1 | 1 | 0 |
| GRPEL1 | GRPEL1 | Q9HAV7 | GrpE protein homolog 1, mitochondrial | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 22 | 88 | 7 | 7 | 0 |
| H2AFZ | H2AZ1 | P0C0S5 | Histone H2A.Z | chr4 | Not Cancer Driver | No | 1 | intact | 23 | 71 | 16 | 16 | 0 |
| HEXA_ENST00000268097 | HEXA | P06865 | Beta-hexosaminidase subunit alpha | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 59 | 5 | 1 | 1 | 49 |
| HEXB | HEXB | P07686 | Beta-hexosaminidase subunit beta | chr5 | Not Cancer Driver | No | 1 | hippie | 45 | 0 | 0 | 0 | 9 |
| HIBCH | HIBCH | Q6NVY1 | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 42 | 26 | 0 | 0 | 1 |
| HIST1H2AH | H2AC12 | Q96KK5 | Histone H2A type 1-H | chr6 | Not Cancer Driver | No | 1 | intact | 31 | 55 | 12 | 12 | 0 |
| HIST1H2BB | H2BC3 | P33778 | Histone H2B type 1-B | chr6 | Not Cancer Driver | No | 1 | intact | 33 | 76 | 19 | 19 | 0 |
| HIST1H4A | H4-16 | P62805 | Histone H4 | chr6 | Not Cancer Driver | No | 1 | intact | 15 | 31 | 5 | 5 | 0 |
| HIST1H4B | H4-16 | P62805 | Histone H4 | chr6 | Not Cancer Driver | No | 1 | intact | 29 | 31 | 6 | 6 | 0 |
| HIST1H4C | H4-16 | P62805 | Histone H4 | chr6 | Not Cancer Driver | No | 1 | intact | 29 | 31 | 7 | 7 | 0 |
| HIST1H4D | H4-16 | P62805 | Histone H4 | chr6 | Not Cancer Driver | No | 1 | intact | 32 | 31 | 8 | 8 | 0 |
| HIST1H4E | H4-16 | P62805 | Histone H4 | chr6 | Not Cancer Driver | No | 1 | intact | 45 | 31 | 14 | 14 | 0 |
| HIST1H4F | H4-16 | P62805 | Histone H4 | chr6 | Not Cancer Driver | No | 1 | intact | 30 | 31 | 7 | 7 | 0 |
| HIST1H4H | H4-16 | P62805 | Histone H4 | chr6 | Not Cancer Driver | No | 1 | intact | 22 | 31 | 9 | 9 | 0 |
| HIST1H4I | H4-16 | P62805 | Histone H4 | chr6 | Not Cancer Driver | No | 1 | intact | 33 | 31 | 10 | 10 | 0 |
| HIST1H4J | H4-16 | P62805 | Histone H4 | chr6 | Not Cancer Driver | No | 1 | intact | 26 | 31 | 9 | 9 | 0 |
| HIST1H4K | H4-16 | P62805 | Histone H4 | chr6 | Not Cancer Driver | No | 1 | intact | 44 | 31 | 13 | 13 | 0 |
| HIST1H4L | H4-16 | P62805 | Histone H4 | chr6 | Not Cancer Driver | No | 1 | intact | 25 | 31 | 14 | 14 | 0 |
| HIST4H4 | H4-16 | P62805 | Histone H4 | chr12 | Not Cancer Driver | No | 1 | intact | 21 | 31 | 7 | 7 | 0 |
| HMOX2_ENST00000406590 | HMOX2 | P30519 | Heme oxygenase 2 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 74 | 10 | 10 | 0 |
| HUS1 | HUS1 | O60921 | Checkpoint protein HUS1 | chr7 | Not Cancer Driver | No | 1 | biogrid | 25 | 17 | 2 | 2 | 0 |
| IARS2 | IARS2 | Q9NSE4 | Isoleucine--tRNA ligase, mitochondrial | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 149 | 145 | 22 | 22 | 0 |
| IKBKE | IKBKE | Q14164 | Inhibitor of nuclear factor kappa-B kinase subunit epsilon | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 108 | 76 | 13 | 13 | 0 |
| IQCB1 | IQCB1 | Q15051 | IQ calmodulin-binding motif-containing protein 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 72 | 88 | 8 | 8 | 0 |
| ISOC2_ENST00000425675 | ISOC2 | Q96AB3 | Isochorismatase domain-containing protein 2 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 8 | 0 | 0 | 0 |
| KCNMA1 | KCNMA1 | Q12791 | Calcium-activated potassium channel subunit alpha-1 | chr10 | Not Cancer Driver | No | 1 | intact | 222 | 225 | 39 | 39 | 5 |
| KLHL6 | KLHL6 | Q8WZ60 | Kelch-like protein 6 | chr3 | Compendium | Yes | 1 | intact, hippie | 149 | 25 | 7 | 7 | 0 |
| KYNU_ENST00000409512 | KYNU | Q16719 | Kynureninase | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 103 | 20 | 5 | 5 | 1 |
| LDHA_ENST00000422447 | LDHA | P00338 | L-lactate dehydrogenase A chain | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 40 | 9 | 0 | 0 | 0 |
| LDHB_ENST00000350669 | LDHB | P07195 | L-lactate dehydrogenase B chain | chr12 | Not Cancer Driver | No | 2 | hippie, biogrid | 47 | 15 | 2 | 2 | 11 |
| LMNB2 | LMNB2 | Q03252 | Lamin-B2 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 67 | 428 | 42 | 42 | 5 |
| LRRK2 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 519 | 90 | 17 | 17 | 23 |
| MDH2 | MDH2 | P40926 | Malate dehydrogenase, mitochondrial | chr7 | Not Cancer Driver | No | 1 | hippie | 39 | 8 | 1 | 1 | 3 |
| MDM2_ENST00000539479 | MDM2 | Q00987 | E3 ubiquitin-protein ligase Mdm2 | chr12 | Census, Compendium | Yes | 1 | hippie | 56 | 297 | 37 | 37 | 0 |
| MMP20 | MMP20 | O60882 | Matrix metalloproteinase-20 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 79 | 69 | 8 | 8 | 0 |
| MSN | MSN | P26038 | Moesin | chrX | Census, Compendium | Yes | 1 | hippie | 108 | 286 | 56 | 56 | 1 |
| MTRR_ENST00000440940 | MTRR | Q9UBK8 | Methionine synthase reductase | chr5 | Not Cancer Driver | No | 1 | hippie | 101 | 84 | 13 | 13 | 5 |
| NANS | NANS | Q9NR45 | Sialic acid synthase | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 29 | 45 | 1 | 1 | 6 |
| NDUFA8 | NDUFA8 | P51970 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 | chr9 | Not Cancer Driver | No | 1 | biogrid | 25 | 33 | 1 | 1 | 2 |
| NDUFA9 | NDUFA9 | Q16795 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial | chr12 | Not Cancer Driver | No | 1 | biogrid | 57 | 8 | 0 | 0 | 2 |
| NDUFB1_ENST00000605997 | NDUFB1 | O75438 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 | chr14 | Not Cancer Driver | No | 1 | biogrid | 5 | 0 | 0 | 0 | 0 |
| NDUFB2_ENST00000247866 | NDUFB2 | O95178 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial | chr7 | Not Cancer Driver | No | 1 | biogrid | 13 | 26 | 3 | 3 | 0 |
| NDUFV1 | NDUFV1 | P49821 | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 66 | 57 | 9 | 9 | 3 |
| NR2C2_ENST00000393102 | NR2C2 | P49116 | Nuclear receptor subfamily 2 group C member 2 | chr3 | Not Cancer Driver | No | 1 | hippie | 62 | 186 | 24 | 24 | 0 |
| NSFL1C_ENST00000216879 | NSFL1C | Q9UNZ2 | NSFL1 cofactor p47 | chr20 | Not Cancer Driver | No | 1 | hippie | 56 | 266 | 39 | 39 | 0 |
| OGFOD1 | OGFOD1 | Q8N543 | Prolyl 3-hydroxylase OGFOD1 | chr16 | Not Cancer Driver | No | 1 | hippie | 44 | 156 | 6 | 6 | 0 |
| OGT | OGT | O15294 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | chrX | Not Cancer Driver | No | 1 | hippie | 156 | 89 | 16 | 16 | 2 |
| OXCT1 | OXCT1 | P55809 | Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial | chr5 | Not Cancer Driver | No | 2 | hippie, biogrid | 80 | 39 | 5 | 5 | 11 |
| PAFAH1B1 | PAFAH1B1 | P43034 | Platelet-activating factor acetylhydrolase IB subunit beta | chr17 | Not Cancer Driver | No | 2 | hippie, biogrid | 42 | 82 | 11 | 11 | 7 |
| PAFAH2_ENST00000374284 | PAFAH2 | Q99487 | Platelet-activating factor acetylhydrolase 2, cytoplasmic | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 62 | 41 | 7 | 7 | 0 |
| PAPSS1 | PAPSS1 | O43252 | Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | chr4 | Not Cancer Driver | No | 1 | hippie | 94 | 82 | 14 | 14 | 0 |
| PDSS2 | PDSS2 | Q86YH6 | All trans-polyprenyl-diphosphate synthase PDSS2 | chr6 | Not Cancer Driver | No | 1 | biogrid | 39 | 7 | 0 | 0 | 1 |
| PGD | PGD | P52209 | 6-phosphogluconate dehydrogenase, decarboxylating | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 73 | 19 | 3 | 3 | 0 |
| PGK1 | PGK1 | P00558 | Phosphoglycerate kinase 1 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 61 | 40 | 5 | 5 | 9 |
| PGM1_ENST00000371084 | PGM1 | P36871 | Phosphoglucomutase-1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 62 | 31 | 3 | 3 | 13 |
| PIM1 | PIM1 | P11309 | Serine/threonine-protein kinase pim-1 | chr6 | Census, Compendium | Yes | 1 | intact, hippie | 71 | 27 | 8 | 8 | 0 |
| PIR_ENST00000380420 | PIR | O00625 | Pirin | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 29 | 185 | 16 | 16 | 0 |
| PKM_ENST00000335181 | PKM | P14618 | Pyruvate kinase PKM | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 78 | 58 | 13 | 13 | 0 |
| PLEKHA4 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 136 | 687 | 128 | 128 | 0 |
| PLEKHA7 | PLEKHA7 | Q6IQ23 | Pleckstrin homology domain-containing family A member 7 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 152 | 919 | 121 | 121 | 0 |
| PNPO | PNPO | Q9NVS9 | Pyridoxine-5'-phosphate oxidase | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 62 | 8 | 8 | 3 |
| POLR1C | POLR1C | O15160 | DNA-directed RNA polymerases I and III subunit RPAC1 | chr6 | Not Cancer Driver | No | 1 | hippie | 34 | 28 | 3 | 3 | 13 |
| PRKAB1 | PRKAB1 | Q9Y478 | 5'-AMP-activated protein kinase subunit beta-1 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 39 | 124 | 13 | 13 | 0 |
| PRKDC | PRKDC | P78527 | DNA-dependent protein kinase catalytic subunit | chr8 | Not Cancer Driver | No | 1 | hippie | 538 | 421 | 61 | 61 | 2 |
| PSAT1 | PSAT1 | Q9Y617 | Phosphoserine aminotransferase | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 54 | 3 | 1 | 1 | 3 |
| PSMD5 | PSMD5 | Q16401 | 26S proteasome non-ATPase regulatory subunit 5 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 2 | 1 | 1 | 0 |
| PTGR1_ENST00000309195 | PTGR1 | Q14914 | Prostaglandin reductase 1 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 40 | 12 | 1 | 1 | 0 |
| PTMA | PTMA | P06454 | Prothymosin alpha | chr2 | Compendium | Yes | 1 | hippie | 10 | 111 | 10 | 10 | 0 |
| PYGB | PYGB | P11216 | Glycogen phosphorylase, brain form | chr20 | Not Cancer Driver | No | 1 | hippie | 118 | 29 | 5 | 5 | 0 |
| PYGL | PYGL | P06737 | Glycogen phosphorylase, liver form | chr14 | Not Cancer Driver | No | 1 | hippie | 98 | 23 | 2 | 2 | 2 |
| RAD23A | RAD23A | P54725 | UV excision repair protein RAD23 homolog A | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 283 | 41 | 41 | 0 |
| RPGRIP1L_ENST00000379925 | RPGRIP1L | Q68CZ1 | Protein fantom | chr16 | Not Cancer Driver | No | 1 | intact, hippie | 177 | 586 | 94 | 94 | 8 |
| SAE1 | SAE1 | Q9UBE0 | SUMO-activating enzyme subunit 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 39 | 90 | 6 | 6 | 0 |
| SAT1 | SAT1 | P21673 | Diamine acetyltransferase 1 | chrX | Not Cancer Driver | No | 1 | intact, hippie | 29 | 0 | 0 | 0 | 0 |
| SH3BGRL3 | SH3BGRL3 | Q9H299 | SH3 domain-binding glutamic acid-rich-like protein 3 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 9 | 34 | 3 | 3 | 0 |
| SIRT7 | SIRT7 | Q9NRC8 | NAD-dependent protein deacetylase sirtuin-7 | chr17 | Not Cancer Driver | No | 1 | hippie | 48 | 163 | 15 | 15 | 0 |
| SOD2_ENST00000367055 | SOD2 | P04179 | Superoxide dismutase [Mn], mitochondrial | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 32 | 25 | 5 | 5 | 0 |
| SPARC | SPARC | P09486 | SPARC | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 60 | 69 | 5 | 5 | 2 |
| SSBP1_ENST00000484178 | SSBP1 | Q04837 | Single-stranded DNA-binding protein, mitochondrial | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 0 | 0 | 0 | 6 |
| SUCLA2 | SUCLA2 | Q9P2R7 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 46 | 6 | 6 | 3 |
| SUCLG1 | SUCLG1 | P53597 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 48 | 57 | 8 | 8 | 3 |
| SUCLG2_ENST00000307227 | SUCLG2 | Q96I99 | Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 48 | 12 | 2 | 2 | 0 |
| SUMO2 | SUMO2 | P61956 | Small ubiquitin-related modifier 2 | chr17 | Not Cancer Driver | No | 1 | hippie | 9 | 69 | 6 | 6 | 0 |
| TATDN1 | TATDN1 | Q6P1N9 | Deoxyribonuclease TATDN1 | chr8 | Not Cancer Driver | No | 1 | hippie | 25 | 0 | 0 | 0 | 0 |
| TEX101_ENST00000598265 | TEX101 | Q9BY14 | Testis-expressed protein 101 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 45 | 2 | 0 | 0 | 0 |
| TKT_ENST00000462138 | TKT | P29401 | Transketolase | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 66 | 86 | 7 | 7 | 1 |
| TNPO2 | TNPO2 | O14787 | Transportin-2 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 99 | 76 | 10 | 10 | 0 |
| TRIP4 | TRIP4 | Q15650 | Activating signal cointegrator 1 | chr15 | Not Cancer Driver | No | 1 | hippie | 71 | 176 | 27 | 27 | 0 |
| TTC19 | TTC19 | Q6DKK2 | Tetratricopeptide repeat protein 19, mitochondrial | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 34 | 76 | 3 | 3 | 0 |
| UBA1 | UBA1 | P22314 | Ubiquitin-like modifier-activating enzyme 1 | chrX | Not Cancer Driver | No | 2 | hippie, biogrid | 117 | 165 | 22 | 22 | 6 |
| UBE2N | UBE2N | P61088 | Ubiquitin-conjugating enzyme E2 N | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 24 | 3 | 3 | 0 |
| UBR7 | UBR7 | Q8N806 | Putative E3 ubiquitin-protein ligase UBR7 | chr14 | Not Cancer Driver | No | 1 | hippie | 41 | 103 | 13 | 13 | 0 |
| UCHL1 | UCHL1 | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 33 | 34 | 7 | 7 | 4 |
| VBP1 | VBP1 | P61758 | Prefoldin subunit 3 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 47 | 7 | 7 | 0 |
| WDFY1 | WDFY1 | Q8IWB7 | WD repeat and FYVE domain-containing protein 1 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 24 | 2 | 2 | 0 |
| XPNPEP1 | XPNPEP1 | Q9NQW7-3 | Isoform 3 of Xaa-Pro aminopeptidase 1 | chr10 | Not Cancer Driver | No | 1 | hippie | 75 | 98 | 6 | 6 | 0 |
| YARS2 | YARS2 | Q9Y2Z4 | Tyrosine--tRNA ligase, mitochondrial | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 59 | 62 | 11 | 11 | 2 |
| YWHAB_ENST00000353703 | YWHAB | P31946 | 14-3-3 protein beta/alpha | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 22 | 109 | 4 | 4 | 0 |
| YWHAE | YWHAE | P62258 | 14-3-3 protein epsilon | chr17 | Census | Yes | 1 | hippie, biogrid | 32 | 41 | 3 | 3 | 0 |
| YWHAG | YWHAG | P61981 | 14-3-3 protein gamma | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 77 | 9 | 9 | 2 |
| YWHAZ_ENST00000395956 | YWHAZ | P63104 | 14-3-3 protein zeta/delta | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 30 | 81 | 10 | 10 | 0 |
| ZDHHC5 | ZDHHC5 | Q9C0B5 | Palmitoyltransferase ZDHHC5 | chr11 | Not Cancer Driver | No | 1 | hippie | 89 | 462 | 63 | 63 | 0 |
| ZNF830 | ZNF830 | Q96NB3 | Zinc finger protein 830 | chr17 | Not Cancer Driver | No | 1 | biogrid | 39 | 312 | 37 | 37 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|