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FDPS_ENST00000368356 ,FDPS ,P14324
  • Uniprot Accession= P14324
  • Ensembl Transcript= ENST00000368356.8
  • Uniprot Name= FDPS
  • Name= Farnesyl pyrophosphate synthase
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 1
  • Number of Interaction partner in biogrid: 76
  • Number of Interaction partner in hippie: 84
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABCE1 ABCE1 P61221 ATP-binding cassette sub-family E member 1 chr4 Not Cancer Driver No 1 hippie 74 36 6 6 0
ABHD16A ABHD16A O95870 Phosphatidylserine lipase ABHD16A chr6 Not Cancer Driver No 1 hippie 69 53 15 15 0
ACAA2 ACAA2 P42765 3-ketoacyl-CoA thiolase, mitochondrial chr18 Not Cancer Driver No 1 hippie, biogrid 42 51 2 2 0
AGMAT AGMAT Q9BSE5 Agmatinase, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 53 106 10 10 0
AIFM3 AIFM3 Q96NN9 Apoptosis-inducing factor 3 chr22 Not Cancer Driver No 1 hippie, biogrid 87 66 15 15 0
ALAS1_ENST00000484952 ALAS1 P13196 5-aminolevulinate synthase, non-specific, mitochondrial chr3 Not Cancer Driver No 2 hippie, biogrid 68 177 16 16 0
ARIH1 ARIH1 Q9Y4X5 E3 ubiquitin-protein ligase ARIH1 chr15 Not Cancer Driver No 1 biogrid 46 119 7 7 0
ATP6AP1 ATP6AP1 Q15904 V-type proton ATPase subunit S1 chrX Not Cancer Driver No 1 biogrid 67 0 0 0 4
ATP6V1G1 ATP6V1G1 O75348 V-type proton ATPase subunit G 1 chr9 Not Cancer Driver No 1 biogrid 12 91 8 8 0
ATPAF2 ATPAF2 Q8N5M1 ATP synthase mitochondrial F1 complex assembly factor 2 chr17 Not Cancer Driver No 2 hippie, biogrid 25 66 4 4 1
ATXN1 ATXN1 P54253 Ataxin-1 chr6 Not Cancer Driver No 1 hippie 193 604 168 168 0
BASP1_ENST00000616743 BASP1 P80723 Brain acid soluble protein 1 chr5 Not Cancer Driver No 1 hippie, biogrid 39 227 39 39 0
BCAP31_ENST00000345046 BCAP31 P51572 B-cell receptor-associated protein 31 chrX Not Cancer Driver No 1 hippie 37 104 14 14 0
BCL2L14 BCL2L14 Q9BZR8 Apoptosis facilitator Bcl-2-like protein 14 chr12 Not Cancer Driver No 1 hippie 29 40 4 4 0
BDP1 BDP1 A6H8Y1 Transcription factor TFIIIB component B'' homolog chr5 Not Cancer Driver No 1 biogrid 293 2495 276 276 0
BNIP1_ENST00000351486 BNIP1 Q12981 Vesicle transport protein SEC20 chr5 Not Cancer Driver No 1 biogrid 43 57 10 10 0
BOD1L1 BOD1L1 Q8NFC6 Biorientation of chromosomes in cell division protein 1-like 1 chr4 Not Cancer Driver No 1 biogrid 387 3023 384 384 0
CCNK CCNK O75909 Cyclin-K chr14 Not Cancer Driver No 1 biogrid 39 347 15 15 1
CDC27_ENST00000066544 CDC27 P30260 Cell division cycle protein 27 homolog chr17 Not Cancer Driver No 1 hippie, biogrid 179 289 75 75 0
CDK12 CDK12 Q9NYV4 Cyclin-dependent kinase 12 chr17 Census, Compendium Yes 1 biogrid 225 1202 160 160 0
CHMP4C CHMP4C Q96CF2 Charged multivesicular body protein 4c chr8 Not Cancer Driver No 1 hippie 33 224 31 31 0
CLIC4 CLIC4 Q9Y696 Chloride intracellular channel protein 4 chr1 Not Cancer Driver No 1 hippie, biogrid 24 49 4 4 0
CLPP CLPP Q16740 ATP-dependent Clp protease proteolytic subunit, mitochondrial chr19 Not Cancer Driver No 1 hippie, biogrid 22 83 9 9 3
CREB3 CREB3 O43889 Cyclic AMP-responsive element-binding protein 3 chr9 Not Cancer Driver No 1 hippie 33 168 11 11 0
CTH CTH P32929 Cystathionine gamma-lyase chr1 Not Cancer Driver No 1 hippie, biogrid 45 49 6 6 2
DDR1_ENST00000324771 DDR1 Q08345 Epithelial discoidin domain-containing receptor 1 chr6 Not Cancer Driver No 1 hippie 123 253 49 49 0
DPH2 DPH2 Q9BQC3 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 chr1 Not Cancer Driver No 1 hippie, biogrid 77 177 26 26 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 444 223 35 35 1
EIF3H EIF3H O15372 Eukaryotic translation initiation factor 3 subunit H chr8 Not Cancer Driver No 1 biogrid 37 109 12 12 0
EIF4ENIF1 EIF4ENIF1 Q9NRA8 Eukaryotic translation initiation factor 4E transporter chr22 Not Cancer Driver No 1 hippie 116 899 101 101 0
EMC1 EMC1 Q8N766 ER membrane protein complex subunit 1 chr1 Not Cancer Driver No 1 biogrid 107 59 6 6 2
EMC2 EMC2 Q15006 ER membrane protein complex subunit 2 chr8 Not Cancer Driver No 1 biogrid 48 29 3 3 0
EMC4 EMC4 Q5J8M3 ER membrane protein complex subunit 4 chr15 Not Cancer Driver No 1 biogrid 15 17 2 2 0
EMC6 EMC6 Q9BV81 ER membrane protein complex subunit 6 chr17 Not Cancer Driver No 1 biogrid 4 0 0 0 0
EMC7 EMC7 Q9NPA0 ER membrane protein complex subunit 7 chr15 Not Cancer Driver No 1 biogrid 35 54 10 10 0
EPHX2 EPHX2 P34913 Bifunctional epoxide hydrolase 2 chr8 Not Cancer Driver No 1 hippie, biogrid 78 26 3 3 0
FDPS_ENST00000368356 FDPS P14324 Farnesyl pyrophosphate synthase chr1 Not Cancer Driver No 2 intact, hippie, biogrid 66 0 0 0 1
FGFR1_ENST00000447712 FGFR1 P11362 Fibroblast growth factor receptor 1 chr8 Census, Compendium Yes 1 hippie 152 230 43 43 74
G6PD_ENST00000621232 G6PD P11413 Glucose-6-phosphate 1-dehydrogenase chrX Not Cancer Driver No 1 hippie, biogrid 86 28 3 3 58
GLDC GLDC P23378 Glycine dehydrogenase (decarboxylating), mitochondrial chr9 Not Cancer Driver No 2 hippie, biogrid 152 112 7 7 22
GPX1_ENST00000620890 GPX1 P07203 Glutathione peroxidase 1 chr3 Not Cancer Driver No 1 hippie, biogrid 38 12 1 1 0
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 hippie 28 10 1 1 0
HIBADH HIBADH P31937 3-hydroxyisobutyrate dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 28 7 2 2 0
HIF1AN HIF1AN Q9NWT6 Hypoxia-inducible factor 1-alpha inhibitor chr10 Not Cancer Driver No 1 hippie 37 77 9 9 0
HNRNPA1 HNRNPA1 P09651 Heterogeneous nuclear ribonucleoprotein A1 chr12 Not Cancer Driver No 1 hippie, biogrid 70 290 58 58 4
HNRNPA1L2 HNRNPA1L2 Q32P51 Heterogeneous nuclear ribonucleoprotein A1-like 2 chr13 Not Cancer Driver No 1 hippie, biogrid 29 235 23 23 0
HNRNPA3 HNRNPA3 P51991 Heterogeneous nuclear ribonucleoprotein A3 chr2 Not Cancer Driver No 1 hippie, biogrid 46 285 37 37 0
HNRNPH1 HNRNPH1 P31943 Heterogeneous nuclear ribonucleoprotein H chr5 Not Cancer Driver No 1 hippie 51 169 29 29 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 hippie, biogrid 149 251 52 52 0
HUS1 HUS1 O60921 Checkpoint protein HUS1 chr7 Not Cancer Driver No 1 biogrid 25 17 2 2 0
IDH1 IDH1 O75874 Isocitrate dehydrogenase [NADP] cytoplasmic chr2 Census, Compendium Yes 1 hippie 553 37 3 3 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 Not Cancer Driver No 1 hippie, biogrid 183 265 37 37 6
IMPDH2 IMPDH2 P12268 Inosine-5'-monophosphate dehydrogenase 2 chr3 Not Cancer Driver No 1 hippie, biogrid 70 6 1 1 0
KSR1_ENST00000644974 KSR1 Q8IVT5 Kinase suppressor of Ras 1 chr17 Not Cancer Driver No 1 hippie 114 404 58 58 0
LILRB3_ENST00000391750 LILRB3 C9JWL8 Leukocyte immunoglobulin-like receptor subfamily B member 3 chr19 Not Cancer Driver No 1 hippie 92 296 55 55 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 hippie 519 90 17 17 23
MBTPS2 MBTPS2 O43462 Membrane-bound transcription factor site-2 protease chrX Not Cancer Driver No 1 biogrid 63 16 4 4 9
MCFD2_ENST00000409973 MCFD2 Q8NI22 Multiple coagulation factor deficiency protein 2 chr2 Not Cancer Driver No 1 hippie, biogrid 16 90 11 11 4
MED23 MED23 Q9ULK4 Mediator of RNA polymerase II transcription subunit 23 chr6 Not Cancer Driver No 1 biogrid 158 28 2 2 1
MED9 MED9 Q9NWA0 Mediator of RNA polymerase II transcription subunit 9 chr17 Not Cancer Driver No 1 biogrid 16 127 15 15 0
MMAB MMAB Q96EY8 Corrinoid adenosyltransferase MMAB chr12 Not Cancer Driver No 1 hippie, biogrid 36 68 14 14 5
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 110 101 8 8 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
NDUFAF5 NDUFAF5 Q5TEU4 Arginine-hydroxylase NDUFAF5, mitochondrial chr20 Not Cancer Driver No 2 hippie, biogrid 47 69 15 15 3
NIP7 NIP7 Q9Y221 60S ribosome subunit biogenesis protein NIP7 homolog chr16 Not Cancer Driver No 1 biogrid 16 1 0 0 0
NME1_ENST00000393196 NME1 P15531 Nucleoside diphosphate kinase A chr17 Not Cancer Driver No 1 hippie 11 10 0 0 0
NME2 NME2 P22392 Nucleoside diphosphate kinase B chr17 Not Cancer Driver No 1 hippie 13 11 1 1 0
NMRAL1 NMRAL1 Q9HBL8 NmrA-like family domain-containing protein 1 chr16 Not Cancer Driver No 1 hippie 39 14 3 3 0
NPEPPS NPEPPS P55786 Puromycin-sensitive aminopeptidase chr17 Compendium Yes 1 hippie, biogrid 102 45 5 5 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
NXF1_ENST00000294172 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 100 163 32 32 0
OTUB1_ENST00000428192 OTUB1 Q96FW1 Ubiquitin thioesterase OTUB1 chr11 Not Cancer Driver No 1 hippie 31 33 2 2 0
PABPC1 PABPC1 P11940 Polyadenylate-binding protein 1 chr8 Census, Compendium Yes 1 hippie, biogrid 100 317 55 55 0
PCYOX1 PCYOX1 Q9UHG3 Prenylcysteine oxidase 1 chr2 Not Cancer Driver No 2 hippie, biogrid 60 9 1 1 0
PDSS1 PDSS1 Q5T2R2 All trans-polyprenyl-diphosphate synthase PDSS1 chr10 Not Cancer Driver No 2 hippie, biogrid 50 51 5 5 1
PDSS2 PDSS2 Q86YH6 All trans-polyprenyl-diphosphate synthase PDSS2 chr6 Not Cancer Driver No 2 hippie, biogrid 39 7 0 0 1
PLAA PLAA Q9Y263 Phospholipase A-2-activating protein chr9 Not Cancer Driver No 1 hippie, biogrid 78 150 14 14 2
PLS3_ENST00000539310 PLS3 P13797 Plastin-3 chrX Not Cancer Driver No 1 hippie 75 75 5 5 0
PMVK PMVK Q15126 Phosphomevalonate kinase chr1 Not Cancer Driver No 1 biogrid 38 3 0 0 0
PPME1_ENST00000328257 PPME1 Q9Y570 Protein phosphatase methylesterase 1 chr11 Not Cancer Driver No 1 hippie 35 146 9 9 0
PPP2R1A PPP2R1A P30153 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 Census, Compendium Yes 1 biogrid 179 0 0 0 4
PRNP PRNP P04156 Major prion protein chr20 Not Cancer Driver No 1 hippie 36 115 7 7 18
PSME4 PSME4 Q14997 Proteasome activator complex subunit 4 chr2 Not Cancer Driver No 2 hippie, biogrid 214 134 12 12 0
PYGM PYGM P11217 Glycogen phosphorylase, muscle form chr11 Not Cancer Driver No 1 hippie, biogrid 153 39 4 4 17
RINT1 RINT1 Q6NUQ1 RAD50-interacting protein 1 chr7 Not Cancer Driver No 1 biogrid 84 55 3 3 2
RMDN3 RMDN3 Q96TC7 Regulator of microtubule dynamics protein 3 chr15 Not Cancer Driver No 1 hippie, biogrid 45 196 17 17 0
RNF19B RNF19B Q6ZMZ0 E3 ubiquitin-protein ligase RNF19B chr1 Not Cancer Driver No 1 hippie 58 344 24 24 0
RPL31_ENST00000264258 RPL31 P62899 60S ribosomal protein L31 chr2 Not Cancer Driver No 1 hippie 19 69 14 14 0
RRM1 RRM1 P23921 Ribonucleoside-diphosphate reductase large subunit chr11 Not Cancer Driver No 1 biogrid 74 41 7 7 0
SEC31A_ENST00000355196 SEC31A O94979 Protein transport protein Sec31A chr4 Not Cancer Driver No 1 hippie, biogrid 139 519 58 58 0
SEPHS1 SEPHS1 P49903 Selenide, water dikinase 1 chr10 Not Cancer Driver No 1 hippie, biogrid 58 29 10 10 0
SLC30A2_ENST00000374278 SLC30A2 Q9BRI3 Zinc transporter 2 chr1 Not Cancer Driver No 1 hippie 46 42 5 5 2
SORD SORD Q00796 Sorbitol dehydrogenase chr15 Not Cancer Driver No 1 hippie 29 41 7 7 3
SPARC SPARC P09486 SPARC chr5 Not Cancer Driver No 1 hippie, biogrid 60 69 5 5 2
SSMEM1 SSMEM1 Q8WWF3 Serine-rich single-pass membrane protein 1 chr7 Not Cancer Driver No 1 hippie 45 181 32 32 0
STAMBP_ENST00000339566 STAMBP O95630 STAM-binding protein chr2 Not Cancer Driver No 1 hippie 51 139 16 16 6
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
TAF1A TAF1A Q15573 TATA box-binding protein-associated factor RNA polymerase I subunit A chr1 Not Cancer Driver No 1 biogrid 49 27 4 4 0
TAF2 TAF2 Q6P1X5 Transcription initiation factor TFIID subunit 2 chr8 Not Cancer Driver No 1 biogrid 129 241 34 34 1
TAGLN_ENST00000530649 TAGLN Q01995 Transgelin chr11 Not Cancer Driver No 1 hippie 20 94 12 12 0
TALDO1 TALDO1 P37837 Transaldolase chr11 Not Cancer Driver No 1 hippie 51 31 4 4 0
TCOF1 TCOF1 Q13428 Treacle protein chr5 Not Cancer Driver No 1 biogrid 142 1454 141 141 1
TEX101_ENST00000598265 TEX101 Q9BY14 Testis-expressed protein 101 chr19 Not Cancer Driver No 1 hippie 45 2 0 0 0
TIMELESS TIMELESS Q9UNS1 Protein timeless homolog chr12 Not Cancer Driver No 1 biogrid 154 367 51 51 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 87 430 41 41 0
TRNAU1AP TRNAU1AP Q9NX07 tRNA selenocysteine 1-associated protein 1 chr1 Not Cancer Driver No 1 biogrid 28 32 4 4 0
TRRAP TRRAP Q9Y4A5 Transformation/transcription domain-associated protein chr7 Census, Compendium Yes 1 biogrid 554 402 59 59 8
TSG101 TSG101 Q99816 Tumor susceptibility gene 101 protein chr11 Not Cancer Driver No 1 hippie 46 159 23 23 0
TTC19 TTC19 Q6DKK2 Tetratricopeptide repeat protein 19, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 34 76 3 3 0
TTC38 TTC38 Q5R3I4 Tetratricopeptide repeat protein 38 chr22 Not Cancer Driver No 1 hippie, biogrid 65 37 3 3 0
UBA2 UBA2 Q9UBT2 SUMO-activating enzyme subunit 2 chr19 Not Cancer Driver No 1 biogrid 84 219 33 33 0
USE1 USE1 Q9NZ43 Vesicle transport protein USE1 chr19 Not Cancer Driver No 1 biogrid 31 101 19 19 0
VPS29_ENST00000549578 VPS29 Q9UBQ0 Vacuolar protein sorting-associated protein 29 chr12 Not Cancer Driver No 1 biogrid 24 0 0 0 0
WDR7 WDR7 Q9Y4E6 WD repeat-containing protein 7 chr18 Not Cancer Driver No 1 biogrid 199 292 37 37 0
WDR77 WDR77 Q9BQA1 Methylosome protein 50 chr1 Not Cancer Driver No 1 biogrid 30 41 2 2 0
XPO1_ENST00000406957 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 2 hippie, biogrid 140 33 9 9 0
ZMPSTE24 ZMPSTE24 O75844 CAAX prenyl protease 1 homolog chr1 Not Cancer Driver No 2 hippie, biogrid 67 23 0 0 3