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FBXO28 ,FBXO28 ,Q9NVF7
  • Uniprot Accession= Q9NVF7
  • Ensembl Transcript= ENST00000366862.9
  • Uniprot Name= FBXO28
  • Name= F-box only protein 28
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 47
  • Number of Interaction partner in biogrid: 61
  • Number of Interaction partner in hippie: 89
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AGGF1 AGGF1 Q8N302 Angiogenic factor with G patch and FHA domains 1 chr5 Not Cancer Driver No 1 hippie 100 582 80 80 1
ANGPT2 ANGPT2 O15123 Angiopoietin-2 chr8 Not Cancer Driver No 2 intact, hippie, biogrid 63 96 10 10 1
ANGPTL3 ANGPTL3 Q9Y5C1 Angiopoietin-related protein 3 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 52 154 26 26 0
ARHGEF6 ARHGEF6 Q15052 Rho guanine nucleotide exchange factor 6 chrX Not Cancer Driver No 3 hippie, biogrid 158 223 45 45 0
ARHGEF7 ARHGEF7 Q14155 Rho guanine nucleotide exchange factor 7 chr13 Not Cancer Driver No 2 intact, hippie, biogrid 106 301 39 39 0
BLOC1S6_ENST00000220531 BLOC1S6 Q9UL45 Biogenesis of lysosome-related organelles complex 1 subunit 6 chr15 Not Cancer Driver No 1 hippie, biogrid 12 111 11 11 0
BRAP BRAP Q7Z569 BRCA1-associated protein chr12 Not Cancer Driver No 1 intact, hippie 70 192 24 24 0
CAPZB_ENST00000375142 CAPZB P47756 F-actin-capping protein subunit beta chr1 Not Cancer Driver No 1 hippie, biogrid 33 66 3 3 0
CAVIN1 CAVIN1 Q6NZI2 Caveolae-associated protein 1 chr17 Not Cancer Driver No 2 intact, hippie 66 280 50 50 0
CCBE1 CCBE1 Q6UXH8 Collagen and calcium-binding EGF domain-containing protein 1 chr18 Not Cancer Driver No 1 hippie, biogrid 92 227 58 58 5
CCDC89 CCDC89 Q8N998 Coiled-coil domain-containing protein 89 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 60 190 24 24 0
CKAP4 CKAP4 Q07065 Cytoskeleton-associated protein 4 chr12 Not Cancer Driver No 1 intact, hippie, biogrid 73 409 55 55 0
CLEC11A CLEC11A Q9Y240 C-type lectin domain family 11 member A chr19 Not Cancer Driver No 3 intact, hippie, biogrid 23 184 20 20 0
CLEC4F CLEC4F Q8N1N0 C-type lectin domain family 4 member F chr2 Not Cancer Driver No 1 hippie, biogrid 126 248 52 52 0
CLEC4G CLEC4G Q6UXB4 C-type lectin domain family 4 member G chr19 Not Cancer Driver No 1 hippie, biogrid 40 35 4 4 0
CSNK2A1_ENST00000400217 CSNK2A1 P68400 Casein kinase II subunit alpha chr20 Not Cancer Driver No 1 hippie 71 75 8 8 4
CTNNA3 CTNNA3 Q9UI47 Catenin alpha-3 chr10 Not Cancer Driver No 1 intact, hippie 269 186 50 50 1
CUL1_ENST00000602748 CUL1 Q13616 Cullin-1 chr7 Not Cancer Driver No 1 hippie 151 65 9 9 0
DCTN2_ENST00000548249 DCTN2 Q13561 Dynactin subunit 2 chr12 Not Cancer Driver No 3 intact, hippie, biogrid 46 253 32 32 0
EGFL8 EGFL8 Q99944 Epidermal growth factor-like protein 8 chr6 Not Cancer Driver No 3 intact, hippie, biogrid 37 56 10 10 0
EMILIN1 EMILIN1 Q9Y6C2 EMILIN-1 chr2 Not Cancer Driver No 3 intact, hippie, biogrid 125 669 69 69 0
EMILIN3 EMILIN3 Q9NT22 EMILIN-3 chr20 Not Cancer Driver No 1 intact, hippie 97 337 40 40 0
EML1_ENST00000262233 EML1 O00423 Echinoderm microtubule-associated protein-like 1 chr14 Not Cancer Driver No 2 intact, hippie, biogrid 146 205 31 31 2
EML4 EML4 Q9HC35 Echinoderm microtubule-associated protein-like 4 chr2 Census, Compendium Yes 2 hippie, biogrid 105 385 41 41 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 121 195 27 27 2
EXOC7 EXOC7 Q9UPT5 Exocyst complex component 7 chr17 Not Cancer Driver No 1 intact, hippie 95 208 30 30 0
FAM81A FAM81A Q8TBF8 Protein FAM81A chr15 Not Cancer Driver No 1 hippie, biogrid 49 157 13 13 0
FBXO28 FBXO28 Q9NVF7 F-box only protein 28 chr1 Not Cancer Driver No 1 intact, hippie 49 230 30 30 0
FGFR1OP2 FGFR1OP2 Q9NVK5 FGFR1 oncogene partner 2 chr12 Not Cancer Driver No 1 hippie, biogrid 25 185 21 21 0
GCC1 GCC1 Q96CN9 GRIP and coiled-coil domain-containing protein 1 chr7 Not Cancer Driver No 1 hippie 118 508 69 69 0
GIT1_ENST00000225394 GIT1 Q9Y2X7 ARF GTPase-activating protein GIT1 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 67 434 42 42 0
GIT2 GIT2 Q14161 ARF GTPase-activating protein GIT2 chr12 Not Cancer Driver No 2 hippie, biogrid 83 492 47 47 0
GK GK P32189 Glycerol kinase chrX Not Cancer Driver No 1 intact, hippie 85 15 3 3 3
GOLGA2_ENST00000611957 GOLGA2 Q08379 Golgin subfamily A member 2 chr9 Not Cancer Driver No 3 intact, hippie 115 854 96 96 0
GOPC GOPC Q9HD26 Golgi-associated PDZ and coiled-coil motif-containing protein chr6 Census Yes 2 intact, hippie, biogrid 56 263 34 34 0
HOMER1 HOMER1 Q86YM7 Homer protein homolog 1 chr5 Not Cancer Driver No 3 intact, hippie, biogrid 46 243 32 32 0
HOMER3_ENST00000542541 HOMER3 Q9NSC5 Homer protein homolog 3 chr19 Not Cancer Driver No 3 intact, hippie, biogrid 31 251 15 15 0
HSF4 HSF4 Q9ULV5 Heat shock factor protein 4 chr16 Not Cancer Driver No 1 hippie, biogrid 37 327 25 25 4
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 1 hippie 106 257 37 37 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 1 intact, hippie 100 254 43 43 0
IKBIP_ENST00000342502 IKBIP Q70UQ0 Inhibitor of nuclear factor kappa-B kinase-interacting protein chr12 Not Cancer Driver No 2 intact, hippie, biogrid 53 69 8 8 0
KPNA1 KPNA1 P52294 Importin subunit alpha-5 chr3 Not Cancer Driver No 1 hippie, biogrid 65 121 18 18 0
KRT80 KRT80 Q6KB66 Keratin, type II cytoskeletal 80 chr12 Not Cancer Driver No 1 hippie, biogrid 54 147 20 20 0
LDHD LDHD Q86WU2 Probable D-lactate dehydrogenase, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie 55 48 6 6 2
LRRCC1 LRRCC1 Q9C099 Leucine-rich repeat and coiled-coil domain-containing protein 1 chr8 Not Cancer Driver No 2 intact, hippie, biogrid 150 414 63 63 0
LSMEM1 LSMEM1 Q8N8F7 Leucine-rich single-pass membrane protein 1 chr7 Not Cancer Driver No 1 hippie, biogrid 13 17 0 0 0
LURAP1L LURAP1L Q8IV03 Leucine rich adaptor protein 1-like chr9 Not Cancer Driver No 3 intact, hippie, biogrid 31 142 16 16 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 Census Yes 1 hippie 95 84 12 12 0
MCM2 MCM2 P49736 DNA replication licensing factor MCM2 chr3 Not Cancer Driver No 1 hippie 104 275 38 38 1
MCUR1 MCUR1 Q96AQ8 Mitochondrial calcium uniporter regulator 1 chr6 Not Cancer Driver No 1 hippie, biogrid 30 65 0 0 0
NCKIPSD NCKIPSD Q9NZQ3 NCK-interacting protein with SH3 domain chr3 Census Yes 2 intact, hippie, biogrid 63 260 28 28 0
NEDD1_ENST00000266742 NEDD1 Q8NHV4 Protein NEDD1 chr12 Not Cancer Driver No 3 hippie, biogrid 87 282 36 36 0
NLRP3_ENST00000391828 NLRP3 Q96P20 NACHT, LRR and PYD domains-containing protein 3 chr1 Not Cancer Driver No 1 intact, hippie 339 64 33 33 37
NUP50 NUP50 Q9UKX7 Nuclear pore complex protein Nup50 chr22 Not Cancer Driver No 3 intact, hippie, biogrid 58 333 40 40 0
NUP58 NUP58 Q9BVL2 Nucleoporin p58/p45 chr13 Not Cancer Driver No 1 intact, hippie 76 377 49 49 0
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 Not Cancer Driver No 3 intact, hippie, biogrid 57 299 30 30 2
PAK2 PAK2 Q13177 Serine/threonine-protein kinase PAK 2 chr3 Compendium Yes 3 hippie, biogrid 89 242 49 49 0
PFDN4 PFDN4 Q9NQP4 Prefoldin subunit 4 chr20 Not Cancer Driver No 2 intact, hippie, biogrid 22 40 6 6 0
PLEKHF2 PLEKHF2 Q9H8W4 Pleckstrin homology domain-containing family F member 2 chr8 Not Cancer Driver No 1 hippie 32 36 4 4 0
PMF1_ENST00000368277 PMF1 Q6P1K2 Polyamine-modulated factor 1 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 20 76 6 6 0
POC1B POC1B Q8TC44 POC1 centriolar protein homolog B chr12 Not Cancer Driver No 2 intact, hippie, biogrid 52 86 8 8 1
PPP4R3A_ENST00000554943 PPP4R3A Q6IN85 Serine/threonine-protein phosphatase 4 regulatory subunit 3A chr14 Not Cancer Driver No 1 intact, hippie 89 255 29 29 0
PSMB1 PSMB1 P20618 Proteasome subunit beta type-1 chr6 Not Cancer Driver No 1 hippie, biogrid 25 14 2 2 0
PSMC3_ENST00000298852 PSMC3 P17980 26S proteasome regulatory subunit 6A chr11 Not Cancer Driver No 4 intact, hippie, biogrid 55 131 10 10 0
RAB11FIP4 RAB11FIP4 Q86YS3 Rab11 family-interacting protein 4 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 76 434 54 54 0
RASEF RASEF Q8IZ41 Ras and EF-hand domain-containing protein chr9 Not Cancer Driver No 1 hippie, biogrid 101 370 47 47 0
RHOU RHOU Q7L0Q8 Rho-related GTP-binding protein RhoU chr1 Not Cancer Driver No 1 hippie 34 63 6 6 0
SDCBP2_ENST00000360779 SDCBP2 Q9H190 Syntenin-2 chr20 Not Cancer Driver No 1 hippie 49 69 9 9 0
SH3KBP1 SH3KBP1 Q96B97 SH3 domain-containing kinase-binding protein 1 chrX Not Cancer Driver No 2 intact, hippie, biogrid 102 530 82 82 0
SKP1_ENST00000517625 SKP1 P63208 S-phase kinase-associated protein 1 chr5 Not Cancer Driver No 8 intact, hippie, biogrid 19 95 17 17 0
SOX13 SOX13 Q9UN79 Transcription factor SOX-13 chr1 Not Cancer Driver No 1 hippie, biogrid 85 564 77 77 0
SPAG5 SPAG5 Q96R06 Sperm-associated antigen 5 chr17 Not Cancer Driver No 1 intact, hippie 136 636 83 83 0
STX1B STX1B P61266 Syntaxin-1B chr16 Not Cancer Driver No 1 hippie 38 155 20 20 2
STXBP4 STXBP4 Q6ZWJ1 Syntaxin-binding protein 4 chr17 Not Cancer Driver No 1 hippie, biogrid 78 211 24 24 0
SUN1 SUN1 O94901 SUN domain-containing protein 1 chr7 Not Cancer Driver No 2 hippie, biogrid 109 246 26 26 0
SYNGAP1_ENST00000646630 SYNGAP1 Q96PV0 Ras/Rap GTPase-activating protein SynGAP chr6 Not Cancer Driver No 1 hippie, biogrid 153 830 90 90 2
TAX1BP3 TAX1BP3 O14907 Tax1-binding protein 3 chr17 Not Cancer Driver No 1 hippie, biogrid 16 51 8 8 0
TCP10L TCP10L Q8TDR4 T-complex protein 10A homolog 1 chr21 Not Cancer Driver No 2 intact, hippie, biogrid 32 213 32 32 0
TMCC3 TMCC3 Q9ULS5 Transmembrane and coiled-coil domain protein 3 chr12 Not Cancer Driver No 2 hippie, biogrid 105 252 70 70 0
TMED9 TMED9 Q9BVK6 Transmembrane emp24 domain-containing protein 9 chr5 Not Cancer Driver No 1 hippie, biogrid 16 22 2 2 0
TMEM266 TMEM266 Q2M3C6 Transmembrane protein 266 chr15 Not Cancer Driver No 1 intact, hippie 77 239 28 28 0
TOP2A TOP2A P11388 DNA topoisomerase 2-alpha chr17 Compendium Yes 1 hippie 150 508 59 59 0
TRAF1 TRAF1 Q13077 TNF receptor-associated factor 1 chr9 Not Cancer Driver No 3 intact, hippie, biogrid 51 63 9 9 0
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 Not Cancer Driver No 4 intact, hippie, biogrid 63 4 1 1 0
TRAF5_ENST00000336184 TRAF5 O00463 TNF receptor-associated factor 5 chr1 Not Cancer Driver No 2 hippie, biogrid 61 59 5 5 0
TRAF7 TRAF7 Q6Q0C0 E3 ubiquitin-protein ligase TRAF7 chr16 Census Yes 2 intact, hippie, biogrid 76 120 14 14 4
TTC9C_ENST00000532583 TTC9C Q8N5M4 Tetratricopeptide repeat protein 9C chr11 Not Cancer Driver No 1 hippie, biogrid 15 81 3 3 0
ZNF7_ENST00000528372 ZNF7 P17097 Zinc finger protein 7 chr8 Not Cancer Driver No 1 hippie, biogrid 95 160 28 28 0
ZWINT ZWINT O95229 ZW10 interactor chr10 Not Cancer Driver No 1 hippie, biogrid 65 168 44 44 0