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FASLG ,FASLG ,P48023
  • Uniprot Accession= P48023
  • Ensembl Transcript= ENST00000367721.2
  • Uniprot Name= FASLG
  • Name= Tumor necrosis factor ligand superfamily member 6
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 9
  • Number of Interaction partner in hippie: 103
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
APBB1 APBB1 O00213 Amyloid beta precursor protein binding family B member 1 chr11 Not Cancer Driver No 1 hippie 105 399 58 58 0
ARHGAP4_ENST00000350060 ARHGAP4 P98171 Rho GTPase-activating protein 4 chrX Not Cancer Driver No 1 hippie 125 464 76 76 0
ARHGAP9_ENST00000393791 ARHGAP9 Q9BRR9 Rho GTPase-activating protein 9 chr12 Not Cancer Driver No 1 hippie 123 408 51 51 0
ARHGDIA_ENST00000580685 ARHGDIA P52565 Rho GDP-dissociation inhibitor 1 chr17 Not Cancer Driver No 1 hippie 25 50 6 6 0
BAIAP2L1 BAIAP2L1 Q9UHR4 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 chr7 Not Cancer Driver No 1 hippie 76 293 42 42 0
BID_ENST00000551952 BID P55957 BH3-interacting domain death agonist chr22 Not Cancer Driver No 1 hippie 23 74 9 9 0
BTK_ENST00000308731 BTK Q06187 Tyrosine-protein kinase BTK chrX Census, Compendium Yes 1 hippie 147 114 27 27 110
CACNB3 CACNB3 P54284 Voltage-dependent L-type calcium channel subunit beta-3 chr12 Not Cancer Driver No 1 hippie 58 258 30 30 0
CACNB4 CACNB4 O00305 Voltage-dependent L-type calcium channel subunit beta-4 chr2 Not Cancer Driver No 1 hippie 82 295 49 49 1
CASP10_ENST00000272879 CASP10 Q92851 Caspase-10 chr2 Not Cancer Driver No 1 hippie 57 126 17 17 3
CASP8_ENST00000432109 CASP8 Q14790 Caspase-8 chr2 Census, Compendium Yes 1 hippie 142 106 12 12 1
CFLAR CFLAR O15519 CASP8 and FADD-like apoptosis regulator chr2 Not Cancer Driver No 1 hippie 40 44 2 2 0
CLPX CLPX O76031 ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial chr15 Not Cancer Driver No 1 hippie, biogrid 66 195 22 22 1
CRK CRK P46108 Adapter molecule crk chr17 Not Cancer Driver No 1 hippie 30 197 23 23 0
CYSRT1 CYSRT1 B8A4K4 Cysteine-rich tail protein 1 chr9 Not Cancer Driver No 1 hippie 9 142 5 5 0
DAXX_ENST00000266000 DAXX Q9UER7 Death domain-associated protein 6 chr6 Census, Compendium Yes 1 hippie 106 549 81 81 0
DLG2_ENST00000398309 DLG2 Q15700 Disks large homolog 2 chr11 Not Cancer Driver No 1 hippie 224 303 107 107 0
DMD DMD P11532 Dystrophin chrX Not Cancer Driver No 1 hippie 895 1399 329 329 14
DNMBP DNMBP Q6XZF7 Dynamin-binding protein chr10 Not Cancer Driver No 1 hippie 208 758 92 92 0
DOCK4 DOCK4 Q8N1I0 Dedicator of cytokinesis protein 4 chr7 Not Cancer Driver No 1 hippie 331 397 80 80 0
ECM1_ENST00000369047 ECM1 Q16610 Extracellular matrix protein 1 chr1 Not Cancer Driver No 1 hippie 91 219 28 28 1
EIF2AK1 EIF2AK1 Q9BQI3 Eukaryotic translation initiation factor 2-alpha kinase 1 chr7 Not Cancer Driver No 3 hippie, biogrid 87 238 29 29 0
EPS8L3_ENST00000361965 EPS8L3 Q8TE67 Epidermal growth factor receptor kinase substrate 8-like protein 3 chr1 Not Cancer Driver No 1 hippie 105 338 57 57 0
EZR EZR P15311 Ezrin chr6 Census Yes 1 hippie 66 295 35 35 0
FADD FADD Q13158 FAS-associated death domain protein chr11 Not Cancer Driver No 1 hippie 26 45 10 10 1
FAS FAS P25445 Tumor necrosis factor receptor superfamily member 6 chr10 Census, Compendium Yes 1 hippie 55 62 18 18 22
FASLG FASLG P48023 Tumor necrosis factor ligand superfamily member 6 chr1 Not Cancer Driver No 1 hippie 65 94 18 18 1
FGR_ENST00000374004 FGR P09769 Tyrosine-protein kinase Fgr chr1 Not Cancer Driver No 1 hippie 85 52 8 8 0
FN1 FN1 P02751 Fibronectin chr2 Compendium Yes 1 hippie 394 1243 185 185 8
FNBP1 FNBP1 Q96RU3 Formin-binding protein 1 chr9 Census Yes 1 hippie 91 460 75 75 0
FYB1_ENST00000515010 FYB1 O15117 FYN-binding protein 1 chr5 Not Cancer Driver No 1 hippie 176 687 161 161 0
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 Not Cancer Driver No 1 hippie 92 70 13 13 0
GRAP GRAP Q13588 GRB2-related adapter protein chr17 Not Cancer Driver No 1 hippie 10 0 0 0 1
GRAP2_ENST00000407075 GRAP2 O75791 GRB2-related adapter protein 2 chr22 Not Cancer Driver No 1 hippie 59 151 20 20 0
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 hippie 28 10 1 1 0
HCK_ENST00000534862 HCK P08631 Tyrosine-protein kinase HCK chr20 Not Cancer Driver No 1 hippie 112 124 25 25 0
ITK ITK Q08881 Tyrosine-protein kinase ITK/TSK chr5 Census Yes 1 hippie 139 43 10 10 1
ITSN2 ITSN2 Q9NZM3 Intersectin-2 chr2 Not Cancer Driver No 1 hippie 207 680 92 92 0
KALRN_ENST00000360013 KALRN O60229 Kalirin chr3 Not Cancer Driver No 1 hippie 544 732 128 128 0
KRT33B KRT33B Q14525 Keratin, type I cuticular Ha3-II chr17 Not Cancer Driver No 1 hippie 87 59 18 18 0
KRT40_ENST00000398486 KRT40 Q6A162 Keratin, type I cytoskeletal 40 chr17 Not Cancer Driver No 1 hippie 70 6 1 1 0
KRTAP11-1 KRTAP11-1 Q8IUC1 Keratin-associated protein 11-1 chr21 Not Cancer Driver No 1 hippie 54 0 0 0 0
KRTAP12-3 KRTAP12-3 P60328 Keratin-associated protein 12-3 chr21 Not Cancer Driver No 1 hippie 18 0 0 0 0
LCK LCK P06239 Tyrosine-protein kinase Lck chr1 Census Yes 1 hippie 86 94 13 13 1
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 Census Yes 1 hippie 95 84 12 12 0
MACC1 MACC1 Q6ZN28 Metastasis-associated in colon cancer protein 1 chr7 Census Yes 1 hippie 164 93 20 20 0
MAPK8_ENST00000374189 MAPK8 P45983 Mitogen-activated protein kinase 8 chr10 Not Cancer Driver No 1 hippie 64 94 9 9 0
MIA MIA Q16674 Melanoma-derived growth regulatory protein chr19 Not Cancer Driver No 1 hippie 18 0 0 0 0
MMP7 MMP7 P09237 Matrilysin chr11 Not Cancer Driver No 1 hippie 39 70 2 2 0
MOSPD2 MOSPD2 Q8NHP6 Motile sperm domain-containing protein 2 chrX Not Cancer Driver No 1 hippie, biogrid 58 143 16 16 0
MPP4 MPP4 Q96JB8 MAGUK p55 subfamily member 4 chr2 Not Cancer Driver No 1 hippie 100 111 16 16 0
MSN MSN P26038 Moesin chrX Census, Compendium Yes 1 hippie 108 286 56 56 1
MYO15A_ENST00000647165 MYO15A Q9UKN7 Unconventional myosin-XV chr17 Not Cancer Driver No 1 hippie 471 1386 172 172 4
NCF1 NCF1 P14598 Neutrophil cytosol factor 1 chr7 Not Cancer Driver No 1 hippie 37 181 12 12 1
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 Not Cancer Driver No 1 hippie 48 111 17 17 0
NCK2_ENST00000393349 NCK2 O43639 Cytoplasmic protein NCK2 chr2 Not Cancer Driver No 1 hippie 89 88 19 19 0
NCKIPSD NCKIPSD Q9NZQ3 NCK-interacting protein with SH3 domain chr3 Census Yes 1 hippie 63 260 28 28 0
NOTCH2NLA NOTCH2NLA Q7Z3S9 Notch homolog 2 N-terminal-like protein A chr1 Not Cancer Driver No 1 hippie 68 17 2 2 0
OSTF1 OSTF1 Q92882 Osteoclast-stimulating factor 1 chr9 Not Cancer Driver No 1 hippie 18 51 2 2 0
P3H3 P3H3 Q8IVL6 Prolyl 3-hydroxylase 3 chr12 Not Cancer Driver No 1 hippie 84 307 40 40 0
P3H4_ENST00000393928 P3H4 Q92791 Endoplasmic reticulum protein SC65 chr17 Not Cancer Driver No 1 hippie, biogrid 46 82 9 9 0
PACSIN1_ENST00000244458 PACSIN1 Q9BY11 Protein kinase C and casein kinase substrate in neurons protein 1 chr6 Not Cancer Driver No 1 hippie 56 318 47 47 0
PACSIN2_ENST00000402229 PACSIN2 Q9UNF0 Protein kinase C and casein kinase substrate in neurons protein 2 chr22 Not Cancer Driver No 1 hippie 51 301 27 27 0
PACSIN3_ENST00000298838 PACSIN3 Q9UKS6 Protein kinase C and casein kinase substrate in neurons protein 3 chr11 Not Cancer Driver No 1 hippie 52 290 31 31 0
PDCD6 PDCD6 O75340 Programmed cell death protein 6 chr5 Not Cancer Driver No 1 hippie 21 24 1 1 0
PIK3CA PIK3CA P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 Census, Compendium Yes 1 hippie 1669 38 11 11 30
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 Census, Compendium Yes 1 hippie 154 268 61 61 2
PIN1 PIN1 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 chr19 Not Cancer Driver No 1 hippie 17 115 12 12 0
PRMT2_ENST00000355680 PRMT2 P55345 Protein arginine N-methyltransferase 2 chr21 Not Cancer Driver No 3 hippie, biogrid 48 70 8 8 0
PRPF40A PRPF40A O75400 Pre-mRNA-processing factor 40 homolog A chr2 Not Cancer Driver No 1 hippie 83 694 57 57 0
PSTPIP1 PSTPIP1 O43586 Proline-serine-threonine phosphatase-interacting protein 1 chr15 Not Cancer Driver No 1 hippie 46 225 26 26 3
PTPN13_ENST00000411767 PTPN13 Q12923 Tyrosine-protein phosphatase non-receptor type 13 chr4 Census, Compendium Yes 1 hippie 299 1231 149 149 0
RGS20 RGS20 O76081 Regulator of G-protein signaling 20 chr8 Not Cancer Driver No 1 hippie 59 194 36 36 0
RHOA RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 99 46 13 13 2
RIMBP3C RIMBP3C A6NJZ7 RIMS-binding protein 3C chr22 Not Cancer Driver No 1 hippie 0 968 0 0 0
SAMSN1_ENST00000400566 SAMSN1 Q9NSI8 SAM domain-containing protein SAMSN-1 chr21 Not Cancer Driver No 1 hippie 112 291 85 85 0
SEC23A SEC23A Q15436 Protein transport protein Sec23A chr14 Not Cancer Driver No 1 hippie 100 73 8 8 1
SH3GL3_ENST00000427482 SH3GL3 Q99963 Endophilin-A3 chr15 Not Cancer Driver No 1 hippie 88 83 23 23 0
SH3PXD2A_ENST00000369774 SH3PXD2A Q5TCZ1 SH3 and PX domain-containing protein 2A chr10 Not Cancer Driver No 1 hippie 141 797 101 101 0
SH3PXD2B SH3PXD2B A1X283 SH3 and PX domain-containing protein 2B chr5 Not Cancer Driver No 1 hippie 122 660 101 101 1
SH3RF2 SH3RF2 Q8TEC5 E3 ubiquitin-protein ligase SH3RF2 chr5 Not Cancer Driver No 1 hippie 151 455 101 101 0
SKAP2 SKAP2 O75563 Src kinase-associated phosphoprotein 2 chr7 Not Cancer Driver No 1 hippie 51 157 19 19 0
SNX18 SNX18 Q96RF0 Sorting nexin-18 chr5 Not Cancer Driver No 1 hippie 54 236 7 7 0
SNX33 SNX33 Q8WV41 Sorting nexin-33 chr15 Not Cancer Driver No 4 hippie, biogrid 63 204 18 18 0
SNX9 SNX9 Q9Y5X1 Sorting nexin-9 chr6 Not Cancer Driver No 2 hippie, biogrid 71 231 23 23 0
SORBS3 SORBS3 O60504 Vinexin chr8 Not Cancer Driver No 1 hippie 62 577 56 56 0
SPTA1_ENST00000368147 SPTA1 P02549 Spectrin alpha chain, erythrocytic 1 chr1 Not Cancer Driver No 1 hippie 1046 707 294 294 21
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 Census Yes 1 hippie 53 130 11 11 1
SRGAP1 SRGAP1 Q7Z6B7 SLIT-ROBO Rho GTPase-activating protein 1 chr12 Not Cancer Driver No 1 hippie 191 553 87 87 4
SRGAP2 SRGAP2 O75044 SLIT-ROBO Rho GTPase-activating protein 2 chr1 Not Cancer Driver No 1 hippie 122 541 71 71 0
SRGAP3 SRGAP3 O43295 SLIT-ROBO Rho GTPase-activating protein 3 chr3 Census, Compendium Yes 1 hippie 195 549 97 97 0
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 hippie 10 76 7 7 0
TEC TEC P42680 Tyrosine-protein kinase Tec chr4 Census, Compendium Yes 1 hippie 91 57 15 15 0
TIPRL TIPRL O75663 TIP41-like protein chr1 Not Cancer Driver No 1 hippie, biogrid 25 25 3 3 0
TJP3_ENST00000541714 TJP3 O95049 Tight junction protein ZO-3 chr19 Not Cancer Driver No 1 hippie 132 684 101 101 0
TMC6 TMC6 Q7Z403 Transmembrane channel-like protein 6 chr17 Not Cancer Driver No 1 hippie, biogrid 72 129 9 9 0
TNFRSF10B TNFRSF10B O14763 Tumor necrosis factor receptor superfamily member 10B chr8 Not Cancer Driver No 1 hippie 44 190 19 19 0
TNFRSF1A TNFRSF1A P19438 Tumor necrosis factor receptor superfamily member 1A chr12 Not Cancer Driver No 1 hippie 58 111 15 15 12
TNFRSF6B TNFRSF6B O95407 Tumor necrosis factor receptor superfamily member 6B chr20 Not Cancer Driver No 1 hippie 22 22 3 3 0
TNS2_ENST00000314250 TNS2 Q63HR2 Tensin-2 chr12 Not Cancer Driver No 1 hippie 132 799 63 63 0
TRIP10 TRIP10 Q15642 Cdc42-interacting protein 4 chr19 Not Cancer Driver No 1 hippie 72 460 61 61 0
TRIP6 TRIP6 Q15654 Thyroid receptor-interacting protein 6 chr7 Not Cancer Driver No 1 hippie 62 268 19 19 0
YES1_ENST00000314574 YES1 P07947 Tyrosine-protein kinase Yes chr18 Not Cancer Driver No 1 hippie 65 62 10 10 0