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EXO1_ENST00000348581 ,EXO1 ,Q9UQ84
  • Uniprot Accession= Q9UQ84
  • Ensembl Transcript= ENST00000348581.9
  • Uniprot Name= EXO1
  • Name= Exonuclease 1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 16
  • Number of Interaction partner in biogrid: 5
  • Number of Interaction partner in hippie: 44
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTR5 ACTR5 Q9H9F9 Actin-related protein 5 chr20 Not Cancer Driver No 1 hippie 63 163 23 23 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 Census, Compendium Yes 1 hippie 469 225 39 39 41
BAP1 BAP1 Q92560 Ubiquitin carboxyl-terminal hydrolase BAP1 chr3 Census, Compendium Yes 1 hippie 141 418 59 59 0
BLM BLM P54132 Bloom syndrome protein chr15 Census Yes 1 hippie 153 667 70 70 8
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 224 1458 174 174 35
CCNA1 CCNA1 P78396 Cyclin-A1 chr13 Not Cancer Driver No 1 hippie 112 82 21 21 0
CCNA2_ENST00000618014 CCNA2 P20248 Cyclin-A2 chr4 Not Cancer Driver No 1 hippie 45 186 19 19 0
CCNB1 CCNB1 P14635 G2/mitotic-specific cyclin-B1 chr5 Not Cancer Driver No 1 hippie 49 145 14 14 0
CCNF CCNF P41002 Cyclin-F chr16 Not Cancer Driver No 1 hippie, biogrid 106 221 23 23 3
CD14 CD14 P08571 Monocyte differentiation antigen CD14 chr5 Not Cancer Driver No 1 intact, hippie 42 60 5 5 0
CDK1 CDK1 P06493 Cyclin-dependent kinase 1 chr10 Not Cancer Driver No 1 hippie 40 1 0 0 0
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 Not Cancer Driver No 1 hippie 24 0 0 0 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 intact, hippie 287 145 18 18 151
COMT COMT P21964 Catechol O-methyltransferase chr22 Not Cancer Driver No 1 intact, hippie 21 5 0 0 0
DCAF1 DCAF1 Q9Y4B6 DDB1- and CUL4-associated factor 1 chr3 Not Cancer Driver No 1 hippie 128 495 44 44 0
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
FAM160A2_ENST00000449352 FHIP1B Q8N612 FHF complex subunit HOOK interacting protein 1B chr11 Not Cancer Driver No 1 intact 129 415 54 54 0
H2AFX H2AX P16104 Histone H2AX chr11 Not Cancer Driver No 1 intact 20 68 10 10 0
KAT2B KAT2B Q92831 Histone acetyltransferase KAT2B chr3 Not Cancer Driver No 1 hippie 107 266 27 27 0
KLC3 KLC3 Q6P597 Kinesin light chain 3 chr19 Not Cancer Driver No 1 intact, hippie 52 338 32 32 0
KPNA4 KPNA4 O00629 Importin subunit alpha-3 chr3 Not Cancer Driver No 1 hippie 59 112 12 12 0
KPNB1 KPNB1 Q14974 Importin subunit beta-1 chr17 Not Cancer Driver No 1 hippie 92 94 11 11 0
LLGL2 LLGL2 Q6P1M3 LLGL scribble cell polarity complex component 2 chr17 Not Cancer Driver No 1 intact, hippie 120 266 26 26 0
MLH1 MLH1 P40692 DNA mismatch repair protein Mlh1 chr3 Census Yes 2 intact, hippie 92 208 22 22 85
MLH3_ENST00000556740 MLH3 Q9UHC1 DNA mismatch repair protein Mlh3 chr14 Not Cancer Driver No 1 hippie 154 593 60 60 9
MSH2 MSH2 P43246 DNA mismatch repair protein Msh2 chr2 Census Yes 3 intact, hippie, biogrid 92 37 4 4 70
MSH3 MSH3 P20585 DNA mismatch repair protein Msh3 chr5 Not Cancer Driver No 1 hippie 100 211 20 20 0
MYEF2 MYEF2 Q9P2K5 Myelin expression factor 2 chr15 Not Cancer Driver No 1 intact, hippie 85 370 45 45 0
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 Not Cancer Driver No 1 hippie 30 22 3 3 1
PLEC PLEC Q15149 Plectin chr8 Not Cancer Driver No 1 intact, hippie 677 2130 272 272 2
PMS1 PMS1 P54277 PMS1 protein homolog 1 chr2 Census Yes 2 intact, hippie 114 283 38 38 0
PMS2 PMS2 P54278 Mismatch repair endonuclease PMS2 chr7 Census, Compendium Yes 1 hippie 117 331 44 44 9
RBBP8_ENST00000327155 RBBP8 Q99708 DNA endonuclease RBBP8 chr18 Not Cancer Driver No 2 intact, hippie 99 750 76 76 1
RPA2_ENST00000373912 RPA2 P15927 Replication protein A 32 kDa subunit chr1 Not Cancer Driver No 1 hippie 28 114 16 16 0
SENP6 SENP6 Q9GZR1 Sentrin-specific protease 6 chr6 Not Cancer Driver No 1 hippie 120 612 59 59 0
SFN SFN P31947 14-3-3 protein sigma chr1 Not Cancer Driver No 1 hippie 27 75 9 9 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
UBE2I UBE2I P63279 SUMO-conjugating enzyme UBC9 chr16 Not Cancer Driver No 1 hippie 16 16 3 3 0
WDR83 WDR83 Q9BRX9 WD repeat domain-containing protein 83 chr19 Not Cancer Driver No 3 hippie, biogrid 28 35 3 3 0
YWHAB_ENST00000353703 YWHAB P31946 14-3-3 protein beta/alpha chr20 Not Cancer Driver No 2 intact, hippie, biogrid 22 109 4 4 0
YWHAE YWHAE P62258 14-3-3 protein epsilon chr17 Census Yes 1 hippie 32 41 3 3 0
YWHAG YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 2 intact, hippie 26 77 9 9 2
YWHAH YWHAH Q04917 14-3-3 protein eta chr22 Not Cancer Driver No 3 intact, hippie, biogrid 15 55 3 3 0
YWHAQ YWHAQ P27348 14-3-3 protein theta chr2 Not Cancer Driver No 1 hippie 29 41 6 6 0
YWHAZ_ENST00000395956 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 1 hippie 30 81 10 10 0