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ERRFI1 ,ERRFI1 ,Q9UJM3
  • Uniprot Accession= Q9UJM3
  • Ensembl Transcript= ENST00000377482.9
  • Uniprot Name= ERRFI1
  • Name= ERBB receptor feedback inhibitor 1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 24
  • Number of Interaction partner in biogrid: 8
  • Number of Interaction partner in hippie: 103
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACBD3 ACBD3 Q9H3P7 Golgi resident protein GCP60 chr1 Not Cancer Driver No 1 hippie 59 350 40 40 0
ACTA1 ACTA1 P68133 Actin, alpha skeletal muscle chr1 Not Cancer Driver No 1 hippie 70 48 14 14 84
ACTA2 ACTA2 P62736 Actin, aortic smooth muscle chr10 Not Cancer Driver No 1 hippie 50 39 4 4 17
ACTBL2 ACTBL2 Q562R1 Beta-actin-like protein 2 chr5 Not Cancer Driver No 1 intact, hippie 73 29 5 5 0
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 1 hippie 112 43 5 5 5
ACTC1 ACTC1 P68032 Actin, alpha cardiac muscle 1 chr15 Not Cancer Driver No 1 hippie 114 48 19 19 11
ACTG1_ENST00000575087 ACTG1 P63261 Actin, cytoplasmic 2 chr17 Not Cancer Driver No 1 hippie 73 42 10 10 16
ACTG2_ENST00000345517 ACTG2 P63267 Actin, gamma-enteric smooth muscle chr2 Not Cancer Driver No 1 hippie 80 39 8 8 21
ALK ALK Q9UM73 ALK tyrosine kinase receptor chr2 Census, Compendium Yes 1 hippie 303 575 114 114 16
ANXA2_ENST00000396024 ANXA2 P07355 Annexin A2 chr15 Not Cancer Driver No 1 intact, hippie 49 20 4 4 0
AOX1 AOX1 Q06278 Aldehyde oxidase chr2 Not Cancer Driver No 1 hippie 238 70 11 11 0
ARRDC5 ARRDC5 A6NEK1 Arrestin domain-containing protein 5 chr19 Not Cancer Driver No 1 hippie 50 47 16 16 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 Census, Compendium Yes 1 intact, hippie 469 225 39 39 41
AURKA_ENST00000395915 AURKA O14965 Aurora kinase A chr20 Not Cancer Driver No 1 hippie 36 178 21 21 0
AXL AXL P30530 Tyrosine-protein kinase receptor UFO chr19 Not Cancer Driver No 1 hippie 168 341 64 64 0
BAG4 BAG4 O95429 BAG family molecular chaperone regulator 4 chr8 Not Cancer Driver No 1 intact, hippie 55 402 49 49 0
BCAR3_ENST00000260502 BCAR3 O75815 Breast cancer anti-estrogen resistance protein 3 chr1 Not Cancer Driver No 1 hippie 102 395 42 42 0
CASP8_ENST00000432109 CASP8 Q14790 Caspase-8 chr2 Census, Compendium Yes 1 intact, hippie 142 106 12 12 1
CCT3 CCT3 P49368 T-complex protein 1 subunit gamma chr1 Not Cancer Driver No 1 intact, hippie 71 95 12 12 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 39 23 2 2 1
CHEK1_ENST00000428830 CHEK1 O14757 Serine/threonine-protein kinase Chk1 chr11 Not Cancer Driver No 1 intact, hippie 58 86 16 16 0
CIAO2B CIAO2B Q9Y3D0 Cytosolic iron-sulfur assembly component 2B chr16 Not Cancer Driver No 1 hippie 9 77 3 3 0
COPS5 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 Not Cancer Driver No 1 hippie 36 32 7 7 0
CRHBP CRHBP P24387 Corticotropin-releasing factor-binding protein chr5 Not Cancer Driver No 1 hippie 61 0 0 0 0
DCTN6 DCTN6 O00399 Dynactin subunit 6 chr8 Not Cancer Driver No 1 hippie 25 45 0 0 0
EFEMP1_ENST00000355426 EFEMP1 Q12805 EGF-containing fibulin-like extracellular matrix protein 1 chr2 Not Cancer Driver No 1 hippie 95 73 21 21 1
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 444 223 35 35 1
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 Census, Compendium Yes 1 hippie 275 314 41 41 1
ERRFI1 ERRFI1 Q9UJM3 ERBB receptor feedback inhibitor 1 chr1 Not Cancer Driver No 1 hippie 55 297 37 37 0
ESRRB_ENST00000512784 ESRRB O95718 Steroid hormone receptor ERR2 chr14 Not Cancer Driver No 1 hippie 90 35 7 7 4
FGFR2_ENST00000358487 FGFR2 P21802 Fibroblast growth factor receptor 2 chr10 Census, Compendium Yes 1 intact, hippie 238 228 44 44 72
FGFR4 FGFR4 P22455 Fibroblast growth factor receptor 4 chr5 Census, Compendium Yes 1 intact, hippie 113 162 28 28 0
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 Not Cancer Driver No 2 intact, hippie, biogrid 92 70 13 13 0
GAS1 GAS1 P54826 Growth arrest-specific protein 1 chr9 Not Cancer Driver No 1 hippie 13 82 4 4 0
GFAP_ENST00000588735 GFAP P14136 Glial fibrillary acidic protein chr17 Not Cancer Driver No 1 hippie 65 288 42 42 62
GNPDA2 GNPDA2 Q8TDQ7 Glucosamine-6-phosphate isomerase 2 chr4 Not Cancer Driver No 1 hippie 32 0 0 0 0
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 4 intact, hippie, biogrid 28 10 1 1 0
GTF2H2C_ENST00000514162 GTF2H2 D6RGC9 General transcription factor IIH subunit 2 chr5 Not Cancer Driver No 1 hippie 6 19 1 1 0
GTF2H2_ENST00000330280 GTF2H2 Q13888 General transcription factor IIH subunit 2 chr5 Not Cancer Driver No 1 hippie 7 43 1 1 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 Not Cancer Driver No 1 hippie 24 200 13 13 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 hippie 149 251 52 52 0
HYDIN HYDIN Q4G0P3 Hydrocephalus-inducing protein homolog chr16 Not Cancer Driver No 1 hippie 875 1017 177 177 0
IL2RG IL2RG P31785 Cytokine receptor common subunit gamma chrX Not Cancer Driver No 1 hippie 56 32 6 6 33
LTK LTK P29376 Leukocyte tyrosine kinase receptor chr15 Not Cancer Driver No 1 hippie 103 301 30 30 0
MASP1_ENST00000337774 MASP1 P48740 Mannan-binding lectin serine protease 1 chr3 Not Cancer Driver No 1 intact, hippie 142 72 14 14 0
MFSD5_ENST00000329548 MFSD5 Q6N075 Molybdate-anion transporter chr12 Not Cancer Driver No 1 hippie 46 11 1 1 0
MMP26 MMP26 Q9NRE1 Matrix metalloproteinase-26 chr11 Not Cancer Driver No 1 hippie 72 19 10 10 0
NEDD4 NEDD4 P46934 E3 ubiquitin-protein ligase NEDD4 chr15 Not Cancer Driver No 1 hippie 150 711 79 79 0
NEU1 NEU1 Q99519 Sialidase-1 chr6 Not Cancer Driver No 1 hippie 52 65 6 6 23
NPC2 NPC2 P61916 NPC intracellular cholesterol transporter 2 chr14 Not Cancer Driver No 1 hippie 8 0 0 0 7
OSTF1 OSTF1 Q92882 Osteoclast-stimulating factor 1 chr9 Not Cancer Driver No 1 hippie 18 51 2 2 0
PALB2 PALB2 Q86YC2 Partner and localizer of BRCA2 chr16 Census Yes 1 intact, hippie 124 769 77 77 1
PAPSS1 PAPSS1 O43252 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 chr4 Not Cancer Driver No 1 hippie 94 82 14 14 0
PCCA PCCA P05165 Propionyl-CoA carboxylase alpha chain, mitochondrial chr13 Not Cancer Driver No 1 hippie 102 42 14 14 16
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 Not Cancer Driver No 1 hippie 30 22 3 3 1
PDCD2 PDCD2 Q16342 Programmed cell death protein 2 chr6 Not Cancer Driver No 1 hippie 32 42 6 6 0
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 Census, Compendium Yes 1 hippie 164 231 44 44 7
PHYHIPL PHYHIPL Q96FC7 Phytanoyl-CoA hydroxylase-interacting protein-like chr10 Not Cancer Driver No 1 hippie 49 68 9 9 0
PLCG1_ENST00000373271 PLCG1 P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 chr20 Census, Compendium Yes 1 hippie, biogrid 158 186 21 21 0
PLEKHA3 PLEKHA3 Q9HB20 Pleckstrin homology domain-containing family A member 3 chr2 Not Cancer Driver No 1 hippie 30 159 19 19 0
POTEE POTEE Q6S8J3 POTE ankyrin domain family member E chr2 Not Cancer Driver No 1 hippie 305 462 92 92 0
POTEF POTEF A5A3E0 POTE ankyrin domain family member F chr2 Not Cancer Driver No 1 hippie 269 453 93 93 0
PPIA PPIA P62937 Peptidyl-prolyl cis-trans isomerase A chr7 Not Cancer Driver No 1 hippie 11 24 3 3 0
PPM1D PPM1D O15297 Protein phosphatase 1D chr17 Census, Compendium Yes 1 hippie 54 370 32 32 0
PSMA7 PSMA7 O14818 Proteasome subunit alpha type-7 chr20 Not Cancer Driver No 1 hippie 24 23 1 1 0
PSMB6 PSMB6 P28072 Proteasome subunit beta type-6 chr17 Not Cancer Driver No 1 hippie 19 22 1 1 0
PUS7_ENST00000469408 PUS7 Q96PZ0 Pseudouridylate synthase 7 homolog chr7 Not Cancer Driver No 1 hippie, biogrid 73 162 17 17 1
RAB18_ENST00000356940 RAB18 Q9NP72 Ras-related protein Rab-18 chr10 Not Cancer Driver No 1 hippie 19 18 2 2 1
RB1CC1 RB1CC1 Q8TDY2 RB1-inducible coiled-coil protein 1 chr8 Not Cancer Driver No 1 intact, hippie 202 578 75 75 0
RNF123 RNF123 Q5XPI4 E3 ubiquitin-protein ligase RNF123 chr3 Not Cancer Driver No 1 hippie 167 220 28 28 0
RPS27A_ENST00000404735 RPS27A P62979 Ubiquitin-40S ribosomal protein S27a chr2 Not Cancer Driver No 1 hippie 18 47 2 2 0
RUBCNL_ENST00000389908 RUBCNL Q9H714 Protein associated with UVRAG as autophagy enhancer chr13 Not Cancer Driver No 1 hippie 92 219 32 32 0
SFN SFN P31947 14-3-3 protein sigma chr1 Not Cancer Driver No 1 hippie 27 75 9 9 0
SH3YL1 SH3YL1 Q96HL8 SH3 domain-containing YSC84-like protein 1 chr2 Not Cancer Driver No 1 hippie 35 108 11 11 0
SHC1_ENST00000368445 SHC1 P29353 SHC-transforming protein 1 chr1 Not Cancer Driver No 1 intact, hippie 84 397 58 58 0
SHC2 SHC2 P98077 SHC-transforming protein 2 chr19 Not Cancer Driver No 1 intact, hippie 66 362 44 44 0
SLC7A13 SLC7A13 Q8TCU3 Solute carrier family 7 member 13 chr8 Not Cancer Driver No 1 hippie 135 0 0 0 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 Census Yes 1 hippie 53 130 11 11 1
STX8 STX8 Q9UNK0 Syntaxin-8 chr17 Not Cancer Driver No 1 hippie 32 98 10 10 0
TC2N_ENST00000340892 TC2N Q8N9U0 Tandem C2 domains nuclear protein chr14 Not Cancer Driver No 1 hippie 83 117 21 21 0
TIMP4 TIMP4 Q99727 Metalloproteinase inhibitor 4 chr3 Not Cancer Driver No 1 hippie 30 8 2 2 0
TM2D3 TM2D3 Q9BRN9 TM2 domain-containing protein 3 chr15 Not Cancer Driver No 1 hippie 31 13 3 3 0
TMEM165 TMEM165 Q9HC07 Transmembrane protein 165 chr4 Not Cancer Driver No 1 hippie 29 75 5 5 3
TMEM59 TMEM59 Q9BXS4 Transmembrane protein 59 chr1 Not Cancer Driver No 1 hippie 39 26 3 3 0
TNKS TNKS O95271 Poly [ADP-ribose] polymerase tankyrase-1 chr8 Not Cancer Driver No 1 intact 163 480 59 59 0
TUBA1A TUBA1A Q71U36 Tubulin alpha-1A chain chr12 Not Cancer Driver No 1 intact, hippie 59 52 11 11 8
TUBA1B TUBA1B P68363 Tubulin alpha-1B chain chr12 Not Cancer Driver No 1 hippie 41 52 9 9 0
TUBA1C_ENST00000301072 TUBA1C Q9BQE3 Tubulin alpha-1C chain chr12 Not Cancer Driver No 1 hippie 39 50 5 5 0
TUBB TUBB P07437 Tubulin beta chain chr6 Not Cancer Driver No 1 hippie 40 63 11 11 5
UBA52_ENST00000595683 UBA52 P62987 Ubiquitin-60S ribosomal protein L40 chr19 Not Cancer Driver No 1 hippie 19 45 8 8 0
UBASH3B UBASH3B Q8TF42 Ubiquitin-associated and SH3 domain-containing protein B chr11 Not Cancer Driver No 1 intact, hippie 86 73 6 6 0
WDR61 WDR61 Q9GZS3 WD repeat-containing protein 61 chr15 Not Cancer Driver No 1 hippie 25 7 1 1 0
WEE1 WEE1 P30291 Wee1-like protein kinase chr11 Not Cancer Driver No 1 hippie 60 399 27 27 0
XPO1_ENST00000406957 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie 140 33 9 9 0
YWHAB_ENST00000353703 YWHAB P31946 14-3-3 protein beta/alpha chr20 Not Cancer Driver No 1 hippie 22 109 4 4 0
YWHAE YWHAE P62258 14-3-3 protein epsilon chr17 Census Yes 3 intact, hippie, biogrid 32 41 3 3 0
YWHAG YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 2 intact, hippie, biogrid 26 77 9 9 2
YWHAH YWHAH Q04917 14-3-3 protein eta chr22 Not Cancer Driver No 2 intact, hippie, biogrid 15 55 3 3 0
YWHAQ YWHAQ P27348 14-3-3 protein theta chr2 Not Cancer Driver No 1 intact, hippie 29 41 6 6 0
YWHAZ_ENST00000395956 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 2 intact, hippie 30 81 10 10 0
ZMAT2 ZMAT2 Q96NC0 Zinc finger matrin-type protein 2 chr5 Not Cancer Driver No 1 hippie, biogrid 24 148 19 19 0
ZPBP ZPBP Q9BS86 Zona pellucida-binding protein 1 chr7 Not Cancer Driver No 1 hippie 100 5 0 0 0