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EPS15 ,EPS15 ,P42566
  • Uniprot Accession= P42566
  • Ensembl Transcript= ENST00000371733.7
  • Uniprot Name= EPS15
  • Name= Epidermal growth factor receptor substrate 15
  • Chromosome= chr1
  • Driver status= Census, Compendium
  • Number of Interaction partner in intact: 85
  • Number of Interaction partner in biogrid: 39
  • Number of Interaction partner in hippie: 191
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
AATK AATK Q6ZMQ8 Serine/threonine-protein kinase LMTK1 chr17 Not Cancer Driver No 1 intact 108 912 75 75 0
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 Census, Compendium Yes 1 hippie 139 604 73 73 2
ACBD5_ENST00000375888 ACBD5 Q5T8D3 Acyl-CoA-binding domain-containing protein 5 chr10 Not Cancer Driver No 1 hippie, biogrid 65 330 45 45 0
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 1 hippie 112 43 5 5 5
ADD1_ENST00000398129 ADD1 P35611 Alpha-adducin chr4 Not Cancer Driver No 1 intact 106 439 64 64 0
AGFG1_ENST00000310078 AGFG1 P52594 Arf-GAP domain and FG repeat-containing protein 1 chr2 Not Cancer Driver No 1 hippie 60 395 50 50 0
AGFG2 AGFG2 O95081 Arf-GAP domain and FG repeat-containing protein 2 chr7 Not Cancer Driver No 1 hippie 62 376 49 49 0
ANLN ANLN Q9NQW6 Anillin chr7 Not Cancer Driver No 1 intact, hippie 144 767 104 104 2
AP1B1 AP1B1 Q10567 AP-1 complex subunit beta-1 chr22 Not Cancer Driver No 2 hippie, biogrid 114 119 10 10 1
AP1G1_ENST00000569748 AP1G1 O43747 AP-1 complex subunit gamma-1 chr16 Not Cancer Driver No 1 hippie 111 144 22 22 0
AP2A1 AP2A1 O95782 AP-2 complex subunit alpha-1 chr19 Not Cancer Driver No 2 intact, hippie 95 188 12 12 0
AP2A2_ENST00000448903 AP2A2 O94973 AP-2 complex subunit alpha-2 chr11 Not Cancer Driver No 2 intact, hippie 100 145 12 12 0
AP2B1_ENST00000621914 AP2B1 P63010 AP-2 complex subunit beta chr17 Not Cancer Driver No 4 intact, hippie, biogrid 85 95 12 12 0
AP2M1_ENST00000292807 AP2M1 Q96CW1 AP-2 complex subunit mu chr3 Not Cancer Driver No 4 intact, hippie, biogrid 55 41 9 9 1
AP2S1_ENST00000263270 AP2S1 P53680 AP-2 complex subunit sigma chr19 Not Cancer Driver No 3 hippie, biogrid 4 0 0 0 3
AURKA_ENST00000395915 AURKA O14965 Aurora kinase A chr20 Not Cancer Driver No 3 hippie, biogrid 36 178 21 21 0
BAIAP2L2 BAIAP2L2 Q6UXY1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 chr22 Not Cancer Driver No 1 intact 41 338 24 24 0
BCL11B BCL11B Q9C0K0 B-cell lymphoma/leukemia 11B chr14 Census, Compendium Yes 1 intact 156 699 114 114 2
BMI1 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 1 intact, hippie 50 150 30 30 0
BMP2K BMP2K Q9NSY1 BMP-2-inducible protein kinase chr4 Not Cancer Driver No 1 intact, hippie 124 827 89 89 0
BRD1_ENST00000216267 BRD1 O95696 Bromodomain-containing protein 1 chr22 Not Cancer Driver No 1 hippie 171 425 68 68 0
CAMTA2_ENST00000348066 CAMTA2 O94983 Calmodulin-binding transcription activator 2 chr17 Not Cancer Driver No 1 intact 148 613 84 84 0
CAPZA2 CAPZA2 P47755 F-actin-capping protein subunit alpha-2 chr7 Not Cancer Driver No 1 hippie 37 19 0 0 0
CCDC172 CCDC172 P0C7W6 Coiled-coil domain-containing protein 172 chr10 Not Cancer Driver No 2 intact, hippie, biogrid 64 72 14 14 0
CCT3 CCT3 P49368 T-complex protein 1 subunit gamma chr1 Not Cancer Driver No 1 hippie 71 95 12 12 0
CD4 CD4 P01730 T-cell surface glycoprotein CD4 chr12 Not Cancer Driver No 1 hippie 69 56 11 11 0
CDC40 CDC40 O60508 Pre-mRNA-processing factor 17 chr6 Not Cancer Driver No 1 intact, hippie 79 214 27 27 1
CDH1 CDH1 P12830 Cadherin-1 chr16 Census, Compendium Yes 1 hippie 150 400 82 82 5
CHD7 CHD7 Q9P2D1 Chromodomain-helicase-DNA-binding protein 7 chr8 Not Cancer Driver No 1 intact 464 1872 299 299 50
CLINT1_ENST00000411809 CLINT1 Q14677 Clathrin interactor 1 chr5 Not Cancer Driver No 1 hippie 61 475 51 51 0
CLTA CLTA P09496 Clathrin light chain A chr9 Not Cancer Driver No 1 hippie, biogrid 20 192 12 12 0
CLTB CLTB P09497 Clathrin light chain B chr5 Not Cancer Driver No 2 intact, hippie, biogrid 33 193 28 28 0
CLTC_ENST00000269122 CLTC Q00610 Clathrin heavy chain 1 chr17 Census, Compendium Yes 1 hippie 190 71 6 6 1
CORO7 CORO7 P57737 Coronin-7 chr16 Not Cancer Driver No 1 hippie 108 347 38 38 0
CRK CRK P46108 Adapter molecule crk chr17 Not Cancer Driver No 2 hippie, biogrid 30 197 23 23 0
CRKL CRKL P46109 Crk-like protein chr22 Not Cancer Driver No 2 hippie, biogrid 38 160 25 25 0
DAB2 DAB2 P98082 Disabled homolog 2 chr5 Not Cancer Driver No 2 intact, hippie 144 680 125 125 0
DBN1_ENST00000309007 DBN1 Q16643 Drebrin chr5 Not Cancer Driver No 1 intact, hippie 84 510 73 73 0
DCAF1 DCAF1 Q9Y4B6 DDB1- and CUL4-associated factor 1 chr3 Not Cancer Driver No 1 hippie 128 495 44 44 0
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 Not Cancer Driver No 1 hippie 118 61 10 10 2
DNAJC5 DNAJC5 Q9H3Z4 DnaJ homolog subfamily C member 5 chr20 Not Cancer Driver No 1 hippie, biogrid 23 46 6 6 1
DNAJC6_ENST00000395325 DNAJC6 O75061 Putative tyrosine-protein phosphatase auxilin chr1 Not Cancer Driver No 1 hippie, biogrid 165 455 82 82 1
DNM1 DNM1 Q05193 Dynamin-1 chr9 Not Cancer Driver No 1 hippie 98 280 23 23 4
DNM2_ENST00000355667 DNM2 P50570 Dynamin-2 chr19 Census Yes 1 hippie 138 270 43 43 22
DRAM1 DRAM1 Q8N682 DNA damage-regulated autophagy modulator protein 1 chr12 Not Cancer Driver No 1 intact 25 0 0 0 0
DVL2 DVL2 O14641 Segment polarity protein dishevelled homolog DVL-2 chr17 Not Cancer Driver No 1 hippie 96 514 64 64 0
DYRK1A_ENST00000644942 DYRK1A Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A chr21 Not Cancer Driver No 1 hippie 135 447 73 73 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 444 223 35 35 1
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
ELF3_ENST00000367283 ELF3 P78545 ETS-related transcription factor Elf-3 chr1 Census, Compendium Yes 1 hippie 94 145 34 34 0
EPHA2 EPHA2 P29317 Ephrin type-A receptor 2 chr1 Compendium Yes 1 hippie 171 187 39 39 3
EPN1_ENST00000270460 EPN1 Q9Y6I3 Epsin-1 chr19 Not Cancer Driver No 1 hippie 87 493 71 71 0
EPN2 EPN2 O95208 Epsin-2 chr17 Not Cancer Driver No 2 intact, hippie 73 543 61 61 0
EPN3 EPN3 Q9H201 Epsin-3 chr17 Not Cancer Driver No 2 intact, hippie 80 522 72 72 0
EPPK1 EPPK1 P58107 Epiplakin chr8 Not Cancer Driver No 1 intact 417 1336 67 67 0
EPS15 EPS15 P42566 Epidermal growth factor receptor substrate 15 chr1 Census, Compendium Yes 3 intact, hippie 106 543 66 66 0
EPS15L1_ENST00000248070 EPS15L1 Q9UBC2 Epidermal growth factor receptor substrate 15-like 1 chr19 Not Cancer Driver No 1 hippie, biogrid 109 603 76 76 0
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 Census, Compendium Yes 1 hippie 275 314 41 41 1
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 121 195 27 27 2
FAM8A1 FAM8A1 Q9UBU6 Protein FAM8A1 chr6 Not Cancer Driver No 1 intact 34 196 14 14 0
FCHO1_ENST00000600676 FCHO1 O14526 F-BAR domain only protein 1 chr19 Not Cancer Driver No 2 intact, hippie, biogrid 127 533 69 69 2
FCHO2 FCHO2 Q0JRZ9 F-BAR domain only protein 2 chr5 Not Cancer Driver No 2 intact, hippie 79 373 45 45 0
FGFR4 FGFR4 P22455 Fibroblast growth factor receptor 4 chr5 Census, Compendium Yes 1 intact 113 162 28 28 0
FLNA FLNA P21333 Filamin-A chrX Census Yes 1 intact, hippie 416 1456 214 214 28
FMR1 FMR1 Q06787 Synaptic functional regulator FMR1 chrX Not Cancer Driver No 1 intact, hippie 124 327 70 70 3
FN1 FN1 P02751 Fibronectin chr2 Compendium Yes 1 intact, hippie 394 1243 185 185 8
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 Not Cancer Driver No 1 hippie 92 70 13 13 0
GAK GAK O14976 Cyclin-G-associated kinase chr4 Not Cancer Driver No 1 intact, hippie 146 589 79 79 0
GJA1 GJA1 P17302 Gap junction alpha-1 protein chr6 Not Cancer Driver No 2 hippie, biogrid 86 110 26 26 50
GNG5_ENST00000370645 GNG5 P63218 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 chr1 Not Cancer Driver No 1 intact 5 9 1 1 0
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 2 intact, hippie 28 10 1 1 0
GRIN2B GRIN2B Q13224 Glutamate receptor ionotropic, NMDA 2B chr12 Not Cancer Driver No 1 intact 413 426 147 147 11
GTSE1 GTSE1 Q9NYZ3 G2 and S phase-expressed protein 1 chr22 Not Cancer Driver No 1 intact, hippie 91 660 85 85 0
HGS HGS O14964 Hepatocyte growth factor-regulated tyrosine kinase substrate chr17 Not Cancer Driver No 1 hippie 109 528 74 74 0
HNRNPL HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 89 283 29 29 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 Not Cancer Driver No 1 hippie 24 200 13 13 0
HSPA1L HSPA1L P34931 Heat shock 70 kDa protein 1-like chr6 Not Cancer Driver No 1 hippie 119 141 28 28 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 Not Cancer Driver No 1 hippie 73 282 35 35 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 hippie 149 251 52 52 0
HSPA9 HSPA9 P38646 Stress-70 protein, mitochondrial chr5 Not Cancer Driver No 1 hippie 67 283 26 26 2
INO80E INO80E Q8NBZ0 INO80 complex subunit E chr16 Not Cancer Driver No 1 hippie, biogrid 21 210 21 21 0
INSYN1 INSYN1 Q2T9L4 Inhibitory synaptic factor 1 chr15 Not Cancer Driver No 1 hippie 44 253 41 41 0
IQGAP1 IQGAP1 P46940 Ras GTPase-activating-like protein IQGAP1 chr15 Not Cancer Driver No 2 intact, hippie 183 351 35 35 0
ITGA4 ITGA4 P13612 Integrin alpha-4 chr2 Not Cancer Driver No 1 hippie 254 97 27 27 0
ITSN1 ITSN1 Q15811 Intersectin-1 chr21 Not Cancer Driver No 3 intact, hippie, biogrid 214 797 107 107 0
ITSN2 ITSN2 Q9NZM3 Intersectin-2 chr2 Not Cancer Driver No 3 intact, hippie, biogrid 207 680 92 92 0
KIAA1549 KIAA1549 Q9HCM3 UPF0606 protein KIAA1549 chr7 Census Yes 1 intact 295 1129 169 169 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
KPNB1 KPNB1 Q14974 Importin subunit beta-1 chr17 Not Cancer Driver No 1 hippie 92 94 11 11 0
KRT1 KRT1 P04264 Keratin, type II cytoskeletal 1 chr12 Not Cancer Driver No 1 hippie 133 426 98 98 20
KRT10 KRT10 P13645 Keratin, type I cytoskeletal 10 chr17 Not Cancer Driver No 1 hippie 79 297 38 38 16
KRT14 KRT14 P02533 Keratin, type I cytoskeletal 14 chr17 Not Cancer Driver No 1 hippie 76 183 31 31 40
KRT16 KRT16 P08779 Keratin, type I cytoskeletal 16 chr17 Not Cancer Driver No 1 hippie 83 152 28 28 16
KRT17 KRT17 Q04695 Keratin, type I cytoskeletal 17 chr17 Not Cancer Driver No 1 hippie 86 160 31 31 18
KRT2 KRT2 P35908 Keratin, type II cytoskeletal 2 epidermal chr12 Not Cancer Driver No 1 hippie 122 335 59 59 15
KRT3 KRT3 P12035 Keratin, type II cytoskeletal 3 chr12 Not Cancer Driver No 1 hippie 119 218 38 38 2
KRT32 KRT32 Q14532 Keratin, type I cuticular Ha2 chr17 Not Cancer Driver No 1 hippie 88 74 20 20 0
KRT33A KRT33A O76009 Keratin, type I cuticular Ha3-I chr17 Not Cancer Driver No 1 hippie 84 54 12 12 0
KRT33B KRT33B Q14525 Keratin, type I cuticular Ha3-II chr17 Not Cancer Driver No 1 hippie 87 59 18 18 0
KRT34 KRT34 O76011 Keratin, type I cuticular Ha4 chr17 Not Cancer Driver No 1 hippie 102 58 21 21 0
KRT35 KRT35 Q92764 Keratin, type I cuticular Ha5 chr17 Not Cancer Driver No 1 hippie 96 66 11 11 0
KRT36 KRT36 O76013 Keratin, type I cuticular Ha6 chr17 Not Cancer Driver No 1 hippie 99 52 18 18 0
KRT37 KRT37 O76014 Keratin, type I cuticular Ha7 chr17 Not Cancer Driver No 1 hippie 105 80 18 18 0
KRT38 KRT38 O76015 Keratin, type I cuticular Ha8 chr17 Not Cancer Driver No 1 hippie 89 52 15 15 0
KRT4 KRT4 P19013 Keratin, type II cytoskeletal 4 chr12 Not Cancer Driver No 1 hippie 116 130 23 23 1
KRT5 KRT5 P13647 Keratin, type II cytoskeletal 5 chr12 Not Cancer Driver No 1 hippie 112 193 47 47 50
KRT6A KRT6A P02538 Keratin, type II cytoskeletal 6A chr12 Not Cancer Driver No 1 hippie 127 138 35 35 24
KRT73 KRT73 Q86Y46 Keratin, type II cytoskeletal 73 chr12 Not Cancer Driver No 1 hippie 121 60 14 14 0
KRT75 KRT75 O95678 Keratin, type II cytoskeletal 75 chr12 Not Cancer Driver No 1 hippie 126 142 35 35 1
KRT79 KRT79 Q5XKE5 Keratin, type II cytoskeletal 79 chr12 Not Cancer Driver No 1 hippie 94 230 43 43 0
KRT82 KRT82 Q9NSB4 Keratin, type II cuticular Hb2 chr12 Not Cancer Driver No 1 hippie 88 16 5 5 0
KRT83 KRT83 P78385 Keratin, type II cuticular Hb3 chr12 Not Cancer Driver No 1 hippie 88 22 3 3 2
KRT85 KRT85 P78386 Keratin, type II cuticular Hb5 chr12 Not Cancer Driver No 1 hippie 97 29 4 4 1
KRT9 KRT9 P35527 Keratin, type I cytoskeletal 9 chr17 Not Cancer Driver No 1 hippie 104 427 68 68 21
KRTAP9-3 KRTAP9-3 Q9BYQ3 Keratin-associated protein 9-3 chr17 Not Cancer Driver No 1 hippie 31 0 0 0 0
LAPTM5 LAPTM5 Q13571 Lysosomal-associated transmembrane protein 5 chr1 Not Cancer Driver No 1 intact, hippie 46 16 6 6 0
LIMA1_ENST00000341247 LIMA1 Q9UHB6 LIM domain and actin-binding protein 1 chr12 Not Cancer Driver No 1 hippie 88 687 81 81 0
LSP1_ENST00000311604 LSP1 P33241 Lymphocyte-specific protein 1 chr11 Not Cancer Driver No 1 intact 44 337 43 43 0
LSR_ENST00000361790 LSR Q86X29 Lipolysis-stimulated lipoprotein receptor chr19 Not Cancer Driver No 2 hippie, biogrid 89 330 42 42 0
MACC1 MACC1 Q6ZN28 Metastasis-associated in colon cancer protein 1 chr7 Census Yes 1 hippie, biogrid 164 93 20 20 0
MAP4 MAP4 P27816 Microtubule-associated protein 4 chr3 Not Cancer Driver No 1 hippie 116 1136 114 114 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 Not Cancer Driver No 1 hippie 39 25 1 1 0
MAPRE1 MAPRE1 Q15691 Microtubule-associated protein RP/EB family member 1 chr20 Not Cancer Driver No 1 hippie 26 109 11 11 0
MCCC2 MCCC2 Q9HCC0 Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial chr5 Not Cancer Driver No 1 intact, hippie 60 25 2 2 52
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 Census, Compendium Yes 1 intact, hippie 56 297 37 37 0
MIB1 MIB1 Q86YT6 E3 ubiquitin-protein ligase MIB1 chr18 Not Cancer Driver No 1 hippie 122 282 34 34 1
MLLT10_ENST00000377059 MLLT10 P55197 Protein AF-10 chr10 Census Yes 1 intact 133 835 94 94 0
MTNR1A MTNR1A P48039 Melatonin receptor type 1A chr4 Not Cancer Driver No 1 intact, hippie 72 0 0 0 0
MYH9 MYH9 P35579 Myosin-9 chr22 Census, Compendium Yes 1 intact, hippie 310 1120 160 160 17
MYO18B_ENST00000335473 MYO18B Q8IUG5 Unconventional myosin-XVIIIb chr22 Not Cancer Driver No 1 intact 541 1541 355 355 0
MYO6 MYO6 Q9UM54 Unconventional myosin-VI chr6 Not Cancer Driver No 1 hippie 176 342 41 41 3
NAA40 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 22 30 3 3 0
NAGPA NAGPA Q9UK23 N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase chr16 Not Cancer Driver No 1 hippie 47 131 11 11 0
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 Not Cancer Driver No 1 intact, hippie 48 111 17 17 0
NECAP1_ENST00000339754 NECAP1 Q8NC96 Adaptin ear-binding coat-associated protein 1 chr12 Not Cancer Driver No 1 hippie 36 140 22 22 0
NECAP2_ENST00000337132 NECAP2 Q9NVZ3 Adaptin ear-binding coat-associated protein 2 chr1 Not Cancer Driver No 1 intact, hippie 21 144 8 8 0
NEDD4 NEDD4 P46934 E3 ubiquitin-protein ligase NEDD4 chr15 Not Cancer Driver No 1 hippie 150 711 79 79 0
NONO NONO Q15233 Non-POU domain-containing octamer-binding protein chrX Census, Compendium Yes 1 hippie 101 349 64 64 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
NUMBL NUMBL Q9Y6R0 Numb-like protein chr19 Not Cancer Driver No 2 intact, hippie 42 467 23 23 0
NUMB_ENST00000355058 NUMB P49757 Protein numb homolog chr14 Not Cancer Driver No 1 hippie 70 490 58 58 0
OCLN OCLN Q16625 Occludin chr5 Not Cancer Driver No 1 hippie 54 244 21 21 1
OPTN_ENST00000263036 OPTN Q96CV9 Optineurin chr10 Not Cancer Driver No 1 hippie 58 470 51 51 6
OXCT1 OXCT1 P55809 Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial chr5 Not Cancer Driver No 2 hippie, biogrid 80 39 5 5 11
PCCB_ENST00000251654 PCCB P05166 Propionyl-CoA carboxylase beta chain, mitochondrial chr3 Not Cancer Driver No 1 hippie 59 64 12 12 25
PCLO PCLO Q9Y6V0 Protein piccolo chr7 Not Cancer Driver No 1 intact 1611 4237 1301 1301 0
PDLIM7 PDLIM7 Q9NR12 PDZ and LIM domain protein 7 chr5 Not Cancer Driver No 1 hippie 48 244 20 20 0
PICALM PICALM Q13492 Phosphatidylinositol-binding clathrin assembly protein chr11 Census Yes 2 hippie, biogrid 89 320 42 42 0
PLEKHA7 PLEKHA7 Q6IQ23 Pleckstrin homology domain-containing family A member 7 chr11 Not Cancer Driver No 1 intact, hippie 152 919 121 121 0
PLK1 PLK1 P53350 Serine/threonine-protein kinase PLK1 chr16 Not Cancer Driver No 1 hippie, biogrid 87 119 13 13 0
POLA1_ENST00000379059 POLA1 P09884 DNA polymerase alpha catalytic subunit chrX Not Cancer Driver No 1 intact 185 347 45 45 3
POLR2J3 POLR2J3 Q9H1A7 DNA-directed RNA polymerase II subunit RPB11-b2 chr7 Not Cancer Driver No 1 hippie, biogrid 3 0 0 0 0
PPP1CB_ENST00000358506 PPP1CB P62140 Serine/threonine-protein phosphatase PP1-beta catalytic subunit chr2 Not Cancer Driver No 1 intact, hippie 47 25 5 5 5
PRDX1_ENST00000319248 PRDX1 Q06830 Peroxiredoxin-1 chr1 Not Cancer Driver No 1 hippie 22 40 5 5 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 Not Cancer Driver No 1 hippie 110 78 15 15 31
PRUNE2 PRUNE2 Q8WUY3 Protein prune homolog 2 chr9 Not Cancer Driver No 1 intact 572 2506 465 465 0
PSMD4_ENST00000368884 PSMD4 P55036 26S proteasome non-ATPase regulatory subunit 4 chr1 Not Cancer Driver No 1 hippie 43 243 25 25 0
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 Not Cancer Driver No 1 intact, hippie 49 140 25 25 0
PTPN13_ENST00000411767 PTPN13 Q12923 Tyrosine-protein phosphatase non-receptor type 13 chr4 Census, Compendium Yes 1 intact, hippie 299 1231 149 149 0
PTPN3 PTPN3 P26045 Tyrosine-protein phosphatase non-receptor type 3 chr9 Not Cancer Driver No 1 hippie 139 214 28 28 0
PYGO2 PYGO2 Q9BRQ0 Pygopus homolog 2 chr1 Not Cancer Driver No 1 intact 51 340 43 43 0
RAB11FIP2_ENST00000355624 RAB11FIP2 Q7L804 Rab11 family-interacting protein 2 chr10 Not Cancer Driver No 1 hippie 66 356 43 43 0
RABL6_ENST00000311502 RABL6 Q3YEC7 Rab-like protein 6 chr9 Not Cancer Driver No 1 hippie 71 529 48 48 0
RAD23A RAD23A P54725 UV excision repair protein RAD23 homolog A chr19 Not Cancer Driver No 1 hippie 50 283 41 41 0
RARRES1 RARRES1 P49788 Retinoic acid receptor responder protein 1 chr3 Not Cancer Driver No 1 hippie, biogrid 24 79 3 3 0
RASAL3 RASAL3 Q86YV0 RAS protein activator like-3 chr19 Not Cancer Driver No 1 intact 114 536 68 68 0
RBM20 RBM20 Q5T481 RNA-binding protein 20 chr10 Not Cancer Driver No 1 intact 55 957 41 41 10
REPS2 REPS2 Q8NFH8 RalBP1-associated Eps domain-containing protein 2 chrX Not Cancer Driver No 1 hippie 94 464 68 68 0
RNF11 RNF11 Q9Y3C5 RING finger protein 11 chr1 Not Cancer Driver No 1 hippie 17 76 7 7 0
RNF26 RNF26 Q9BY78 E3 ubiquitin-protein ligase RNF26 chr11 Not Cancer Driver No 1 hippie 44 71 7 7 0
RNPS1_ENST00000301730 RNPS1 Q15287 RNA-binding protein with serine-rich domain 1 chr16 Not Cancer Driver No 1 hippie, biogrid 30 305 30 30 0
RPL6 RPL6 Q02878 60S ribosomal protein L6 chr12 Not Cancer Driver No 1 hippie 41 159 24 24 0
RUFY4_ENST00000344321 RUFY4 Q6ZNE9 RUN and FYVE domain-containing protein 4 chr2 Not Cancer Driver No 1 hippie, biogrid 77 307 51 51 0
RUNDC3A RUNDC3A Q59EK9 RUN domain-containing protein 3A chr17 Not Cancer Driver No 2 intact, hippie, biogrid 39 175 8 8 0
RUNX3_ENST00000308873 RUNX3 Q13761 Runt-related transcription factor 3 chr1 Not Cancer Driver No 1 intact 59 331 45 45 0
SAP130_ENST00000259235 SAP130 Q9H0E3 Histone deacetylase complex subunit SAP130 chr2 Not Cancer Driver No 1 intact 119 940 107 107 0
SCAMP1 SCAMP1 O15126 Secretory carrier-associated membrane protein 1 chr5 Not Cancer Driver No 1 hippie 29 117 14 14 0
SCAMP2 SCAMP2 O15127 Secretory carrier-associated membrane protein 2 chr15 Not Cancer Driver No 1 intact 34 111 9 9 0
SGIP1 SGIP1 Q9BQI5 SH3-containing GRB2-like protein 3-interacting protein 1 chr1 Not Cancer Driver No 2 hippie, biogrid 210 559 152 152 0
SH3BP4_ENST00000392011 SH3BP4 Q9P0V3 SH3 domain-binding protein 4 chr2 Not Cancer Driver No 1 hippie 143 241 43 43 0
SLC25A3 SLC25A3 Q00325 Phosphate carrier protein, mitochondrial chr12 Not Cancer Driver No 1 intact 49 32 4 4 1
SLC25A41 SLC25A41 Q8N5S1 Mitochondrial carrier protein SCaMC-3L chr19 Not Cancer Driver No 3 hippie, biogrid 54 59 7 7 0
SLC6A3 SLC6A3 Q01959 Sodium-dependent dopamine transporter chr5 Not Cancer Driver No 1 hippie 150 31 8 8 2
SNAP91_ENST00000369694 SNAP91 O60641 Clathrin coat assembly protein AP180 chr6 Not Cancer Driver No 2 hippie, biogrid 203 636 118 118 0
SPART_ENST00000355182 SPART Q8N0X7 Spartin chr13 Not Cancer Driver No 1 hippie 112 396 68 68 1
SPATA31E1 SPATA31E1 Q6ZUB1 Spermatogenesis-associated protein 31E1 chr9 Not Cancer Driver No 1 intact 265 1213 230 230 0
SPC25 SPC25 Q9HBM1 Kinetochore protein Spc25 chr2 Not Cancer Driver No 3 hippie, biogrid 15 34 2 2 0
SPOPL SPOPL Q6IQ16 Speckle-type POZ protein-like chr2 Not Cancer Driver No 1 hippie 87 40 14 14 0
STAM2 STAM2 O75886 Signal transducing adapter molecule 2 chr2 Not Cancer Driver No 1 hippie 69 291 30 30 0
STAMBPL1_ENST00000371924 STAMBPL1 Q96FJ0 AMSH-like protease chr10 Not Cancer Driver No 2 hippie, biogrid 48 70 7 7 0
STAMBP_ENST00000339566 STAMBP O95630 STAM-binding protein chr2 Not Cancer Driver No 1 hippie 51 139 16 16 6
STK40_ENST00000373132 STK40 Q8N2I9 Serine/threonine-protein kinase 40 chr1 Not Cancer Driver No 1 hippie 50 103 9 9 0
STON2_ENST00000267540 STON2 Q8WXE9 Stonin-2 chr14 Not Cancer Driver No 1 hippie 153 449 77 77 0
SYCE1_ENST00000343131 SYCE1 Q8N0S2 Synaptonemal complex central element protein 1 chr10 Not Cancer Driver No 1 hippie, biogrid 70 251 50 50 0
SYNC SYNC Q9H7C4 Syncoilin chr1 Not Cancer Driver No 1 hippie, biogrid 30 358 22 22 0
SYNE2_ENST00000344113 SYNE2 Q8WXH0 Nesprin-2 chr14 Not Cancer Driver No 1 intact 779 1888 220 220 1
SYNJ1 SYNJ1 O43426 Synaptojanin-1 chr21 Not Cancer Driver No 1 hippie 208 584 76 76 3
SYNPO SYNPO Q8N3V7 Synaptopodin chr5 Not Cancer Driver No 1 intact, hippie 103 918 102 102 0
SYT1_ENST00000393240 SYT1 P21579 Synaptotagmin-1 chr12 Not Cancer Driver No 1 hippie 104 103 36 36 5
TFAP2A TFAP2A P05549 Transcription factor AP-2-alpha chr6 Not Cancer Driver No 1 hippie 77 275 44 44 4
TFRC_ENST00000392396 TFRC P02786 Transferrin receptor protein 1 chr3 Census Yes 1 intact, hippie 89 80 6 6 1
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 Not Cancer Driver No 1 hippie 41 41 4 4 10
TMEM108 TMEM108 Q6UXF1 Transmembrane protein 108 chr3 Not Cancer Driver No 1 intact 101 458 89 89 0
TMEM114 TMEM114 B3SHH9 Transmembrane protein 114 chr16 Not Cancer Driver No 1 intact 1 7 0 0 0
TMEM17 TMEM17 Q86X19 Transmembrane protein 17 chr2 Not Cancer Driver No 1 intact, hippie 22 14 2 2 0
TMEM179B TMEM179B Q7Z7N9 Transmembrane protein 179B chr11 Not Cancer Driver No 1 intact 14 8 0 0 0
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 Not Cancer Driver No 1 intact, hippie 63 4 1 1 0
TRIM56 TRIM56 Q9BRZ2 E3 ubiquitin-protein ligase TRIM56 chr7 Not Cancer Driver No 1 hippie 110 217 36 36 0
TUBB TUBB P07437 Tubulin beta chain chr6 Not Cancer Driver No 1 hippie 40 63 11 11 5
UBE2D1 UBE2D1 P51668 Ubiquitin-conjugating enzyme E2 D1 chr10 Not Cancer Driver No 1 hippie 13 14 0 0 0
UBE2D2 UBE2D2 P62837 Ubiquitin-conjugating enzyme E2 D2 chr5 Compendium Yes 1 hippie 19 13 1 1 0
UBE2D3_ENST00000394801 UBE2D3 P61077 Ubiquitin-conjugating enzyme E2 D3 chr4 Not Cancer Driver No 1 hippie 21 13 4 4 0
UBE2E1 UBE2E1 P51965 Ubiquitin-conjugating enzyme E2 E1 chr3 Not Cancer Driver No 1 hippie 21 78 10 10 0
UBE2H UBE2H P62256 Ubiquitin-conjugating enzyme E2 H chr7 Not Cancer Driver No 1 hippie 20 55 11 11 0
UBQLN1 UBQLN1 Q9UMX0 Ubiquilin-1 chr9 Not Cancer Driver No 1 hippie 64 543 58 58 0
UBQLN2 UBQLN2 Q9UHD9 Ubiquilin-2 chrX Not Cancer Driver No 2 intact, hippie 82 581 79 79 8
UBQLN3 UBQLN3 Q9H347 Ubiquilin-3 chr11 Not Cancer Driver No 1 intact 164 441 117 117 0
UBQLNL UBQLNL Q8IYU4 Ubiquilin-like protein chr11 Not Cancer Driver No 1 intact 109 286 71 71 0
USP8 USP8 P40818 Ubiquitin carboxyl-terminal hydrolase 8 chr15 Census, Compendium Yes 1 hippie 122 602 69 69 0
VASP VASP P50552 Vasodilator-stimulated phosphoprotein chr19 Not Cancer Driver No 1 hippie, biogrid 39 335 34 34 0
VCAM1 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 Not Cancer Driver No 2 intact, hippie 188 110 28 28 0
VSIG10L2 VSIG10L2 P0DP72 V-set and immunoglobulin domain-containing protein 10-like 2 chr11 Not Cancer Driver No 1 intact 2 238 2 2 0
WDR59 WDR59 Q6PJI9 GATOR complex protein WDR59 chr16 Not Cancer Driver No 1 intact 119 199 33 33 0
WEE1 WEE1 P30291 Wee1-like protein kinase chr11 Not Cancer Driver No 1 intact 60 399 27 27 0
WNK3_ENST00000375159 WNK3 Q9BYP7 Serine/threonine-protein kinase WNK3 chrX Not Cancer Driver No 1 hippie, biogrid 281 1281 200 200 0
XPO1_ENST00000406957 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie 140 33 9 9 0
ZCCHC10 ZCCHC10 Q8TBK6 Zinc finger CCHC domain-containing protein 10 chr5 Not Cancer Driver No 1 hippie, biogrid 12 144 11 11 0
ZDHHC8_ENST00000334554 ZDHHC8 Q9ULC8 Palmitoyltransferase ZDHHC8 chr22 Not Cancer Driver No 1 intact 99 490 69 69 0
ZIC1 ZIC1 Q15915 Zinc finger protein ZIC 1 chr3 Not Cancer Driver No 1 intact 187 246 113 113 1
ZIC3 ZIC3 O60481 Zinc finger protein ZIC 3 chrX Not Cancer Driver No 1 intact 100 327 66 66 10