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EPRS ,EPRS1 ,P07814
  • Uniprot Accession= P07814
  • Ensembl Transcript= ENST00000366923.7
  • Uniprot Name= EPRS1
  • Name= Bifunctional glutamate/proline--tRNA ligase
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 55
  • Number of Interaction partner in biogrid: 0
  • Number of Interaction partner in hippie: 0
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AGO1 AGO1 Q9UL18 Protein argonaute-1 chr1 Not Cancer Driver No 1 intact 126 87 11 11 0
AGO2 AGO2 Q9UKV8 Protein argonaute-2 chr8 Not Cancer Driver No 1 intact 126 141 15 15 11
AIMP1_ENST00000442366 AIMP1 Q12904 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 chr4 Not Cancer Driver No 1 intact 31 161 19 19 0
BAG2 BAG2 O95816 BAG family molecular chaperone regulator 2 chr6 Not Cancer Driver No 1 intact 17 112 9 9 0
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 Not Cancer Driver No 1 intact 48 5 1 1 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 2 intact 287 145 18 18 151
COQ2_ENST00000647002 COQ2 Q96H96 4-hydroxybenzoate polyprenyltransferase, mitochondrial chr4 Not Cancer Driver No 1 intact 23 25 0 0 17
CUL1_ENST00000602748 CUL1 Q13616 Cullin-1 chr7 Not Cancer Driver No 1 intact 151 65 9 9 0
CUL3 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 intact 123 167 23 23 3
DLD DLD P09622 Dihydrolipoyl dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 intact 67 17 0 0 10
DLST DLST P36957 Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial chr14 Not Cancer Driver No 1 intact 53 190 32 32 1
DTX4 DTX4 Q9Y2E6 E3 ubiquitin-protein ligase DTX4 chr11 Not Cancer Driver No 1 intact 84 323 57 57 0
EEF1D_ENST00000395119 EEF1D P29692 Elongation factor 1-delta chr8 Not Cancer Driver No 1 intact 40 153 22 22 0
EPRS EPRS1 P07814 Bifunctional glutamate/proline--tRNA ligase chr1 Not Cancer Driver No 1 intact 204 372 62 62 1
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 intact 90 92 11 11 1
HIST2H2BE H2BC21 Q16778 Histone H2B type 2-E chr1 Not Cancer Driver No 1 intact 47 77 30 30 0
HIST3H3 H3-4 Q16695 Histone H3.1t chr1 Not Cancer Driver No 1 intact 37 51 10 10 0
HSCB HSCB Q8IWL3 Iron-sulfur cluster co-chaperone protein HscB chr22 Not Cancer Driver No 2 intact 36 25 6 6 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 1 intact 106 257 37 37 0
IARS IARS1 P41252 Isoleucine--tRNA ligase, cytoplasmic chr9 Not Cancer Driver No 4 intact 130 28 4 4 4
IKBKB IKBKB O14920 Inhibitor of nuclear factor kappa-B kinase subunit beta chr8 Census, Compendium Yes 1 intact 106 211 31 31 1
IKBKE IKBKE Q14164 Inhibitor of nuclear factor kappa-B kinase subunit epsilon chr1 Not Cancer Driver No 1 intact 108 76 13 13 0
KARS_ENST00000302445 KARS1 Q15046 Lysine--tRNA ligase chr16 Not Cancer Driver No 3 intact 88 160 15 15 12
LARS LARS1 Q9P2J5 Leucine--tRNA ligase, cytoplasmic chr5 Not Cancer Driver No 1 intact 133 97 10 10 1
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 2 intact 519 90 17 17 23
MAP3K14 MAP3K14 Q99558 Mitogen-activated protein kinase kinase kinase 14 chr17 Not Cancer Driver No 1 intact 94 543 52 52 0
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 Not Cancer Driver No 1 intact 104 333 66 66 6
MAPK13 MAPK13 O15264 Mitogen-activated protein kinase 13 chr6 Not Cancer Driver No 1 intact 51 50 15 15 0
MCC_ENST00000302475 MCC P23508 Colorectal mutant cancer protein chr5 Not Cancer Driver No 1 intact 136 589 92 92 0
MST1R MST1R Q04912 Macrophage-stimulating protein receptor chr3 Not Cancer Driver No 1 intact 178 182 27 27 1
NCAPH2_ENST00000420993 NCAPH2 Q6IBW4 Condensin-2 complex subunit H2 chr22 Not Cancer Driver No 1 intact 67 335 39 39 0
NDN NDN Q99608 Necdin chr15 Not Cancer Driver No 1 intact 123 117 42 42 0
NELFCD NELFCD Q8IXH7 Negative elongation factor C/D chr20 Not Cancer Driver No 1 intact 69 53 1 1 0
NFKB2 NFKB2 Q00653 Nuclear factor NF-kappa-B p100 subunit chr10 Census, Compendium Yes 1 intact 86 510 46 46 0
NFKBIB NFKBIB Q15653 NF-kappa-B inhibitor beta chr19 Not Cancer Driver No 1 intact 42 223 29 29 0
NPM1 NPM1 P06748 Nucleophosmin chr5 Census, Compendium Yes 1 intact 29 249 22 22 0
PDCD11 PDCD11 Q14690 Protein RRP5 homolog chr10 Not Cancer Driver No 1 intact 212 487 64 64 0
PKN2 PKN2 Q16513 Serine/threonine-protein kinase N2 chr1 Not Cancer Driver No 1 intact 123 415 48 48 0
PLEKHA7 PLEKHA7 Q6IQ23 Pleckstrin homology domain-containing family A member 7 chr11 Not Cancer Driver No 1 intact 152 919 121 121 0
QARS QARS1 P47897 Glutamine--tRNA ligase chr3 Not Cancer Driver No 1 intact 101 106 16 16 4
RARS RARS1 P54136 Arginine--tRNA ligase, cytoplasmic chr5 Not Cancer Driver No 2 intact 72 41 3 3 2
RELA RELA Q04206 Transcription factor p65 chr11 Compendium Yes 1 intact 75 400 48 48 0
RELB RELB Q01201 Transcription factor RelB chr19 Not Cancer Driver No 1 intact 65 348 39 39 0
RIN3 RIN3 Q8TB24 Ras and Rab interactor 3 chr14 Not Cancer Driver No 1 intact 137 417 61 61 0
RIPK3 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 Not Cancer Driver No 1 intact 66 295 39 39 0
SDCBP_ENST00000260130 SDCBP O00560 Syntenin-1 chr8 Not Cancer Driver No 1 intact 39 17 2 2 0
SDHA SDHA P31040 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial chr5 Census Yes 1 intact 115 71 13 13 7
SMARCB1_ENST00000644036 SMARCB1 Q12824 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 chr22 Census, Compendium Yes 1 intact 64 141 35 35 3
SOAT1 SOAT1 P35610 Sterol O-acyltransferase 1 chr1 Not Cancer Driver No 1 intact 73 49 4 4 0
TAB1 TAB1 Q15750 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 chr22 Not Cancer Driver No 1 intact 81 232 34 34 0
TFE3 TFE3 P19532 Transcription factor E3 chrX Census Yes 1 intact 92 524 84 84 0
VCAM1 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 Not Cancer Driver No 1 intact 188 110 28 28 0
VDAC1_ENST00000395047 VDAC1 P21796 Voltage-dependent anion-selective channel protein 1 chr5 Not Cancer Driver No 1 intact 38 36 4 4 0
YWHAZ_ENST00000395956 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 1 intact 30 81 10 10 0