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EPHX1_ENST00000366837 ,EPHX1 ,P07099
  • Number of Interaction partner in intact: 18
  • Number of Interaction partner in biogrid: 52
  • Number of Interaction partner in hippie: 72
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABAT_ENST00000268251 ABAT P80404 4-aminobutyrate aminotransferase, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 84 28 5 5 1
ASS1_ENST00000352480 ASS1 P00966 Argininosuccinate synthase chr9 Not Cancer Driver No 1 hippie, biogrid 65 63 8 8 86
ATG2A ATG2A Q2TAZ0 Autophagy-related protein 2 homolog A chr11 Not Cancer Driver No 1 intact, hippie 228 887 124 124 0
ATP4A ATP4A P20648 Potassium-transporting ATPase alpha chain 1 chr19 Not Cancer Driver No 1 hippie 201 121 30 30 0
BCAR1_ENST00000162330 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 Not Cancer Driver No 1 hippie 108 677 75 75 0
BDNF_ENST00000439476 BDNF P23560 Brain-derived neurotrophic factor chr11 Not Cancer Driver No 1 intact, hippie 47 79 19 19 1
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
BRD2_ENST00000374831 BRD2 P25440 Bromodomain-containing protein 2 chr6 Not Cancer Driver No 1 hippie 108 632 85 85 0
CCDC107 CCDC107 Q8WV48 Coiled-coil domain-containing protein 107 chr9 Not Cancer Driver No 1 hippie, biogrid 14 215 12 12 0
CDKN2AIP CDKN2AIP Q9NXV6 CDKN2A-interacting protein chr4 Not Cancer Driver No 1 hippie, biogrid 53 352 38 38 0
CHRNA9 CHRNA9 Q9UGM1 Neuronal acetylcholine receptor subunit alpha-9 chr4 Not Cancer Driver No 1 hippie, biogrid 76 23 6 6 0
CHRND CHRND Q07001 Acetylcholine receptor subunit delta chr2 Not Cancer Driver No 1 hippie, biogrid 110 71 19 19 7
CKMT1A_ENST00000626814 CKMT1A F8WCN3 Creatine kinase chr15 Not Cancer Driver No 1 biogrid 5 70 1 1 0
CKMT1B_ENST00000441322 CKMT1B P12532 Creatine kinase U-type, mitochondrial chr15 Not Cancer Driver No 1 hippie, biogrid 25 77 1 1 0
CLRN2 CLRN2 A0PK11 Clarin-2 chr4 Not Cancer Driver No 1 hippie, biogrid 54 0 0 0 1
CYP26B1 CYP26B1 Q9NR63 Cytochrome P450 26B1 chr2 Not Cancer Driver No 1 hippie, biogrid 113 10 3 3 2
DERL1 DERL1 Q9BUN8 Derlin-1 chr8 Not Cancer Driver No 1 intact, hippie 28 11 1 1 0
DNAJB11_ENST00000265028 DNAJB11 Q9UBS4 DnaJ homolog subfamily B member 11 chr3 Not Cancer Driver No 1 hippie, biogrid 52 141 21 21 2
EMC2 EMC2 Q15006 ER membrane protein complex subunit 2 chr8 Not Cancer Driver No 1 hippie 48 29 3 3 0
EVA1C EVA1C P58658 Protein eva-1 homolog C chr21 Not Cancer Driver No 2 intact, hippie, biogrid 47 60 2 2 0
FAM189A2 FAM189A2 Q15884 Protein FAM189A2 chr9 Not Cancer Driver No 2 intact, hippie, biogrid 62 231 29 29 0
FAM20C FAM20C Q8IXL6 Extracellular serine/threonine protein kinase FAM20C chr7 Not Cancer Driver No 1 hippie 33 188 3 3 9
HADHA HADHA P40939 Trifunctional enzyme subunit alpha, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 72 19 2 2 5
HPDL HPDL Q96IR7 4-hydroxyphenylpyruvate dioxygenase-like protein chr1 Not Cancer Driver No 1 hippie, biogrid 30 58 11 11 2
IFT20_ENST00000395418 IFT20 Q8IY31 Intraflagellar transport protein 20 homolog chr17 Not Cancer Driver No 1 hippie, biogrid 11 0 0 0 0
IL17RA IL17RA Q96F46 Interleukin-17 receptor A chr22 Not Cancer Driver No 1 hippie, biogrid 92 301 20 20 0
IL22RA1 IL22RA1 Q8N6P7 Interleukin-22 receptor subunit alpha-1 chr1 Not Cancer Driver No 1 hippie, biogrid 66 297 37 37 0
IQCF1 IQCF1 Q8N6M8 IQ domain-containing protein F1 chr3 Not Cancer Driver No 1 hippie, biogrid 43 70 16 16 0
ISG15 ISG15 P05161 Ubiquitin-like protein ISG15 chr1 Not Cancer Driver No 1 hippie 12 24 2 2 0
KCNA2_ENST00000638616 KCNA2 P16389 Potassium voltage-gated channel subfamily A member 2 chr1 Not Cancer Driver No 1 hippie, biogrid 96 82 16 16 5
KCNC3 KCNC3 Q14003 Potassium voltage-gated channel subfamily C member 3 chr19 Not Cancer Driver No 1 hippie, biogrid 76 405 29 29 4
KCNS3_ENST00000304101 KCNS3 Q9BQ31 Potassium voltage-gated channel subfamily S member 3 chr2 Not Cancer Driver No 2 intact, hippie, biogrid 103 23 2 2 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact 519 90 17 17 23
MFSD8_ENST00000296468 MFSD8 Q8NHS3 Major facilitator superfamily domain-containing protein 8 chr4 Not Cancer Driver No 2 intact, hippie, biogrid 69 16 3 3 16
MORF4L1 MORF4L1 Q9UBU8 Mortality factor 4-like protein 1 chr15 Not Cancer Driver No 1 hippie, biogrid 43 163 17 17 0
NKAIN1 NKAIN1 Q4KMZ8 Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 20 0 0 0 0
NMUR2 NMUR2 Q9GZQ4 Neuromedin-U receptor 2 chr5 Not Cancer Driver No 1 intact, hippie, biogrid 139 5 1 1 0
NPC1 NPC1 O15118 NPC intracellular cholesterol transporter 1 chr18 Not Cancer Driver No 1 hippie 155 24 0 0 150
NR3C1_ENST00000343796 NR3C1 P04150 Glucocorticoid receptor chr5 Not Cancer Driver No 1 hippie 92 362 37 37 12
NXF1_ENST00000294172 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 100 163 32 32 0
OPTN_ENST00000263036 OPTN Q96CV9 Optineurin chr10 Not Cancer Driver No 1 hippie, biogrid 58 470 51 51 6
OSGEP OSGEP Q9NPF4 tRNA N6-adenosine threonylcarbamoyltransferase chr14 Not Cancer Driver No 1 hippie, biogrid 46 32 4 4 14
PCDHB3 PCDHB3 Q9Y5E6 Protocadherin beta-3 chr5 Not Cancer Driver No 1 hippie, biogrid 258 119 30 30 0
PCDHGA5 PCDHGA5 Q9Y5G8 Protocadherin gamma-A5 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 253 339 75 75 0
PCDHGB4 PCDHGB4 Q9UN71 Protocadherin gamma-B4 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 211 330 83 83 0
PCDHGB5 PCDHGB5 Q9Y5G0 Protocadherin gamma-B5 chr5 Not Cancer Driver No 1 hippie, biogrid 87 336 34 34 0
PCDHGC4 PCDHGC4 Q9Y5F7 Protocadherin gamma-C4 chr5 Not Cancer Driver No 1 hippie, biogrid 136 460 59 59 0
PIGH PIGH Q14442 Phosphatidylinositol N-acetylglucosaminyltransferase subunit H chr14 Not Cancer Driver No 1 hippie, biogrid 12 1 0 0 1
PTAFR_ENST00000305392 PTAFR P25105 Platelet-activating factor receptor chr1 Not Cancer Driver No 1 hippie, biogrid 42 0 0 0 0
PTGER3_ENST00000370931 PTGER3 P43115 Prostaglandin E2 receptor EP3 subtype chr1 Not Cancer Driver No 2 intact, hippie, biogrid 79 17 2 2 0
RAB34_ENST00000436730 RAB34 Q9BZG1 Ras-related protein Rab-34 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 41 1 0 0 0
RGS2 RGS2 P41220 Regulator of G-protein signaling 2 chr1 Not Cancer Driver No 1 hippie, biogrid 30 50 4 4 0
RNF139 RNF139 Q8WU17 E3 ubiquitin-protein ligase RNF139 chr8 Not Cancer Driver No 1 hippie 76 68 4 4 0
RNF2 RNF2 Q99496 E3 ubiquitin-protein ligase RING2 chr1 Not Cancer Driver No 1 hippie 40 203 22 22 0
RNF4 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 Not Cancer Driver No 1 hippie 14 117 7 7 0
RXFP1_ENST00000307765 RXFP1 Q9HBX9 Relaxin receptor 1 chr4 Not Cancer Driver No 1 hippie, biogrid 152 0 0 0 0
SHISA2 SHISA2 Q6UWI4 Protein shisa-2 homolog chr13 Not Cancer Driver No 1 hippie, biogrid 44 143 29 29 0
SIDT2_ENST00000620360 SIDT2 Q8NBJ9 SID1 transmembrane family member 2 chr11 Not Cancer Driver No 1 hippie, biogrid 113 23 6 6 0
SPINT2 SPINT2 O43291 Kunitz-type protease inhibitor 2 chr19 Not Cancer Driver No 3 intact, hippie, biogrid 46 25 3 3 1
SPRY2 SPRY2 O43597 Protein sprouty homolog 2 chr13 Not Cancer Driver No 1 hippie, biogrid 46 169 29 29 1
SRPRB SRPRB Q9Y5M8 Signal recognition particle receptor subunit beta chr3 Not Cancer Driver No 3 intact, hippie, biogrid 30 23 3 3 0
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 hippie 10 76 7 7 0
TEX101_ENST00000598265 TEX101 Q9BY14 Testis-expressed protein 101 chr19 Not Cancer Driver No 1 intact, hippie 45 2 0 0 0
TFDP2 TFDP2 Q14188 Transcription factor Dp-2 chr3 Not Cancer Driver No 1 hippie, biogrid 62 248 33 33 0
TMED10 TMED10 P49755 Transmembrane emp24 domain-containing protein 10 chr14 Not Cancer Driver No 1 hippie, biogrid 24 15 3 3 0
TMEM30A TMEM30A Q9NV96 Cell cycle control protein 50A chr6 Not Cancer Driver No 2 intact, hippie, biogrid 50 76 8 8 0
TMEM9B TMEM9B Q9NQ34 Transmembrane protein 9B chr11 Not Cancer Driver No 1 hippie, biogrid 12 0 0 0 0
TMX1 TMX1 Q9H3N1 Thioredoxin-related transmembrane protein 1 chr14 Not Cancer Driver No 1 hippie, biogrid 34 59 6 6 0
TRAF1 TRAF1 Q13077 TNF receptor-associated factor 1 chr9 Not Cancer Driver No 2 intact, hippie, biogrid 51 63 9 9 0
TREML2 TREML2 Q5T2D2 Trem-like transcript 2 protein chr6 Not Cancer Driver No 1 hippie, biogrid 66 125 25 25 0
TSPAN17_ENST00000515708 TSPAN17 Q96FV3 Tetraspanin-17 chr5 Not Cancer Driver No 3 hippie, biogrid 23 0 0 0 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
WASHC3 WASHC3 Q9Y3C0 WASH complex subunit 3 chr12 Not Cancer Driver No 1 hippie 29 100 8 8 0
ZNRF4 ZNRF4 Q8WWF5 E3 ubiquitin-protein ligase ZNRF4 chr19 Not Cancer Driver No 1 hippie 115 99 26 26 0