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EPHA8 ,EPHA8 ,P29322
  • Uniprot Accession= P29322
  • Ensembl Transcript= ENST00000166244.7
  • Uniprot Name= EPHA8
  • Name= Ephrin type-A receptor 8
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 90
  • Number of Interaction partner in biogrid: 13
  • Number of Interaction partner in hippie: 30
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AAAS AAAS Q9NRG9 Aladin chr12 Not Cancer Driver No 1 intact 58 116 12 12 3
ABHD15 ABHD15 Q6UXT9 Protein ABHD15 chr17 Not Cancer Driver No 1 hippie, biogrid 50 41 3 3 0
AK4 AK4 P27144 Adenylate kinase 4, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 26 24 3 3 0
ALDOC_ENST00000395321 ALDOC P09972 Fructose-bisphosphate aldolase C chr17 Not Cancer Driver No 1 intact 41 79 4 4 0
ANKLE2 ANKLE2 Q86XL3 Ankyrin repeat and LEM domain-containing protein 2 chr12 Not Cancer Driver No 1 intact 127 521 71 71 2
ANKS1A ANKS1A Q92625 Ankyrin repeat and SAM domain-containing protein 1A chr6 Not Cancer Driver No 1 hippie 120 756 75 75 0
ANKS1B ANKS1B Q7Z6G8 Ankyrin repeat and sterile alpha motif domain-containing protein 1B chr12 Not Cancer Driver No 1 hippie 254 659 150 150 0
ARF4 ARF4 P18085 ADP-ribosylation factor 4 chr3 Not Cancer Driver No 1 intact 17 0 0 0 0
ARFGAP2 ARFGAP2 Q8N6H7 ADP-ribosylation factor GTPase-activating protein 2 chr11 Not Cancer Driver No 1 intact 62 345 40 40 0
ARFGAP3 ARFGAP3 Q9NP61 ADP-ribosylation factor GTPase-activating protein 3 chr22 Not Cancer Driver No 1 intact 53 321 38 38 0
BANF1_ENST00000445560 BANF1 O75531 Barrier-to-autointegration factor chr11 Not Cancer Driver No 1 intact 10 11 2 2 1
BMP1 BMP1 P13497 Bone morphogenetic protein 1 chr8 Not Cancer Driver No 1 hippie, biogrid 119 154 25 25 3
BTK_ENST00000308731 BTK Q06187 Tyrosine-protein kinase BTK chrX Census, Compendium Yes 1 hippie, biogrid 147 114 27 27 110
C9orf72 C9orf72 Q96LT7 Guanine nucleotide exchange factor C9orf72 chr9 Not Cancer Driver No 1 intact 64 11 0 0 0
CALM1 CALM1 P0DP23 Calmodulin-1 chr14 Not Cancer Driver No 1 intact 19 115 15 15 7
CANX_ENST00000504734 CANX P27824 Calnexin chr5 Not Cancer Driver No 1 intact 65 334 38 38 0
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 Census, Compendium Yes 1 hippie 115 512 56 56 4
CDC37 CDC37 Q16543 Hsp90 co-chaperone Cdc37 chr19 Not Cancer Driver No 1 intact 52 214 31 31 0
CDKAL1 CDKAL1 Q5VV42 Threonylcarbamoyladenosine tRNA methylthiotransferase chr6 Not Cancer Driver No 1 intact 80 120 14 14 0
CKAP4 CKAP4 Q07065 Cytoskeleton-associated protein 4 chr12 Not Cancer Driver No 1 intact 73 409 55 55 0
CLCC1 CLCC1 Q96S66 Chloride channel CLIC-like protein 1 chr1 Not Cancer Driver No 1 intact 37 196 19 19 1
COPA_ENST00000241704 COPA P53621 Coatomer subunit alpha chr1 Not Cancer Driver No 1 intact 163 157 18 18 4
COPB1_ENST00000439561 COPB1 P53618 Coatomer subunit beta chr11 Not Cancer Driver No 1 intact 110 95 10 10 1
COPB2 COPB2 P35606 Coatomer subunit beta' chr3 Not Cancer Driver No 1 intact 111 114 22 22 0
COPE_ENST00000262812 COPE O14579 Coatomer subunit epsilon chr19 Not Cancer Driver No 1 intact 29 47 6 6 0
COPG1 COPG1 Q9Y678 Coatomer subunit gamma-1 chr3 Not Cancer Driver No 1 intact 108 107 13 13 0
CRKL CRKL P46109 Crk-like protein chr22 Not Cancer Driver No 1 intact 38 160 25 25 0
DARS2 DARS2 Q6PI48 Aspartate--tRNA ligase, mitochondrial chr1 Not Cancer Driver No 1 hippie 63 91 11 11 11
DDOST_ENST00000375048 DDOST P39656 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit chr1 Not Cancer Driver No 1 intact 34 13 3 3 1
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 Not Cancer Driver No 1 intact 34 181 23 23 0
EBAG9_ENST00000620557 EBAG9 O00559 Receptor-binding cancer antigen expressed on SiSo cells chr8 Not Cancer Driver No 1 intact 35 173 29 29 0
EFNA1 EFNA1 P20827 Ephrin-A1 chr1 Not Cancer Driver No 1 hippie 29 46 5 5 0
EFNA4_ENST00000368409 EFNA4 P52798 Ephrin-A4 chr1 Not Cancer Driver No 2 hippie, biogrid 28 17 3 3 0
EFNA5 EFNA5 P52803 Ephrin-A5 chr5 Not Cancer Driver No 4 intact, hippie, biogrid 34 25 6 6 0
EMC1 EMC1 Q8N766 ER membrane protein complex subunit 1 chr1 Not Cancer Driver No 1 intact 107 59 6 6 2
ENDOG ENDOG Q14249 Endonuclease G, mitochondrial chr9 Not Cancer Driver No 2 intact, hippie, biogrid 11 61 1 1 0
ENTR1 ENTR1 Q96C92 Endosome-associated-trafficking regulator 1 chr9 Not Cancer Driver No 1 intact 64 267 38 38 0
EPHA7 EPHA7 Q15375 Ephrin type-A receptor 7 chr6 Census, Compendium Yes 1 hippie, biogrid 280 71 15 15 0
EPHA8 EPHA8 P29322 Ephrin type-A receptor 8 chr1 Not Cancer Driver No 1 hippie 197 121 17 17 0
FTSJ1 FTSJ1 Q9UET6 Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase chrX Not Cancer Driver No 1 intact 44 89 14 14 0
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 Not Cancer Driver No 1 hippie 92 70 13 13 0
G3BP1 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 Not Cancer Driver No 1 intact, hippie 85 352 65 65 0
GORASP2 GORASP2 Q9H8Y8 Golgi reassembly-stacking protein 2 chr2 Not Cancer Driver No 1 intact 55 287 31 31 0
GRAMD1A GRAMD1A Q96CP6 Protein Aster-A chr19 Not Cancer Driver No 1 intact 83 261 33 33 0
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 intact 28 10 1 1 0
HAL HAL P42357 Histidine ammonia-lyase chr12 Not Cancer Driver No 1 intact 98 34 6 6 4
HSCB HSCB Q8IWL3 Iron-sulfur cluster co-chaperone protein HscB chr22 Not Cancer Driver No 1 intact, hippie 36 25 6 6 0
HSPA4L_ENST00000508776 HSPA4L O95757 Heat shock 70 kDa protein 4L chr4 Not Cancer Driver No 1 intact 105 266 28 28 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 Not Cancer Driver No 2 intact, hippie, biogrid 73 282 35 35 0
HSPH1_ENST00000320027 HSPH1 Q92598 Heat shock protein 105 kDa chr13 Not Cancer Driver No 1 intact 103 323 42 42 0
INSRR INSRR P14616 Insulin receptor-related protein chr1 Not Cancer Driver No 1 intact 262 228 37 37 0
JPH1 JPH1 Q9HDC5 Junctophilin-1 chr8 Not Cancer Driver No 1 intact 131 421 89 89 0
LAMB2 LAMB2 P55268 Laminin subunit beta-2 chr3 Not Cancer Driver No 1 hippie, biogrid 234 463 67 67 9
LGALS3BP LGALS3BP Q08380 Galectin-3-binding protein chr17 Not Cancer Driver No 1 intact 62 9 0 0 0
LMAN1 LMAN1 P49257 Protein ERGIC-53 chr18 Not Cancer Driver No 1 intact 63 222 25 25 1
LRRC49_ENST00000260382 LRRC49 Q8IUZ0 Leucine-rich repeat-containing protein 49 chr15 Not Cancer Driver No 1 intact 117 124 21 21 0
LRRC59 LRRC59 Q96AG4 Leucine-rich repeat-containing protein 59 chr17 Not Cancer Driver No 1 intact 33 122 15 15 0
LRRK1 LRRK1 Q38SD2 Leucine-rich repeat serine/threonine-protein kinase 1 chr15 Not Cancer Driver No 1 intact, hippie 289 261 33 33 0
LSG1 LSG1 Q9H089 Large subunit GTPase 1 homolog chr3 Not Cancer Driver No 1 intact 73 369 42 42 0
MKRN2 MKRN2 Q9H000 E3 ubiquitin-protein ligase makorin-2 chr3 Not Cancer Driver No 1 hippie 45 145 16 16 0
MON2 MON2 Q7Z3U7 Protein MON2 homolog chr12 Not Cancer Driver No 1 intact 201 151 16 16 0
MTHFR_ENST00000376590 MTHFR P42898 Methylenetetrahydrofolate reductase chr1 Not Cancer Driver No 1 intact 95 125 22 22 53
NDC1 NDC1 Q9BTX1 Nucleoporin NDC1 chr1 Not Cancer Driver No 1 intact 62 92 12 12 0
NUDCD3 NUDCD3 Q8IVD9 NudC domain-containing protein 3 chr7 Not Cancer Driver No 1 intact 30 199 16 16 0
OSBPL2_ENST00000643981 OSBPL2 Q9H1P3 Oxysterol-binding protein-related protein 2 chr20 Not Cancer Driver No 1 intact 57 173 18 18 0
PDZD8 PDZD8 Q8NEN9 PDZ domain-containing protein 8 chr10 Not Cancer Driver No 1 intact 126 484 65 65 0
PFKL PFKL P17858 ATP-dependent 6-phosphofructokinase, liver type chr21 Not Cancer Driver No 1 intact 91 29 4 4 0
PFKP PFKP Q01813 ATP-dependent 6-phosphofructokinase, platelet type chr10 Not Cancer Driver No 1 intact 133 43 10 10 0
PIK3CG PIK3CG P48736 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform chr7 Not Cancer Driver No 1 hippie 318 121 39 39 0
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 Census, Compendium Yes 1 intact 154 268 61 61 2
PIK3R2_ENST00000617130 PIK3R2 O00459 Phosphatidylinositol 3-kinase regulatory subunit beta chr19 Not Cancer Driver No 1 intact 96 418 47 47 3
PKM_ENST00000335181 PKM P14618 Pyruvate kinase PKM chr15 Not Cancer Driver No 1 hippie 78 58 13 13 0
PPP1R15B PPP1R15B Q5SWA1 Protein phosphatase 1 regulatory subunit 15B chr1 Not Cancer Driver No 1 intact 72 415 45 45 1
PSMC5 PSMC5 P62195 26S proteasome regulatory subunit 8 chr17 Not Cancer Driver No 1 intact, hippie 52 64 6 6 0
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 Not Cancer Driver No 1 intact 49 140 25 25 0
PTPRD PTPRD P23468 Receptor-type tyrosine-protein phosphatase delta chr9 Census, Compendium Yes 1 intact, hippie 577 747 219 219 0
PYCR2 PYCR2 Q96C36 Pyrroline-5-carboxylate reductase 2 chr1 Not Cancer Driver No 1 intact 31 41 3 3 2
RAB3A RAB3A P20336 Ras-related protein Rab-3A chr19 Not Cancer Driver No 1 hippie, biogrid 25 43 4 4 0
RAB7A RAB7A P51149 Ras-related protein Rab-7a chr3 Not Cancer Driver No 1 intact 27 11 0 0 4
RABL3 RABL3 Q5HYI8 Rab-like protein 3 chr3 Not Cancer Driver No 1 intact 37 1 0 0 1
SEC13_ENST00000350697 SEC13 P55735 Protein SEC13 homolog chr3 Not Cancer Driver No 1 intact 34 36 6 6 0
SEC23A SEC23A Q15436 Protein transport protein Sec23A chr14 Not Cancer Driver No 1 intact 100 73 8 8 1
SEC23IP SEC23IP Q9Y6Y8 SEC23-interacting protein chr10 Not Cancer Driver No 1 intact 112 371 40 40 0
SEC24B_ENST00000265175 SEC24B O95487 Protein transport protein Sec24B chr4 Not Cancer Driver No 1 intact 135 526 55 55 0
SEC31A_ENST00000355196 SEC31A O94979 Protein transport protein Sec31A chr4 Not Cancer Driver No 1 intact 139 519 58 58 0
SMCR8 SMCR8 Q8TEV9 Guanine nucleotide exchange protein SMCR8 chr17 Not Cancer Driver No 1 intact 107 357 38 38 0
SRPRA SRPRA P08240 Signal recognition particle receptor subunit alpha chr11 Not Cancer Driver No 1 intact 95 232 40 40 0
STAM STAM Q92783 Signal transducing adapter molecule 1 chr10 Not Cancer Driver No 1 intact 73 361 40 40 0
STAM2 STAM2 O75886 Signal transducing adapter molecule 2 chr2 Not Cancer Driver No 1 intact 69 291 30 30 0
STIM1_ENST00000300737 STIM1 Q13586 Stromal interaction molecule 1 chr11 Not Cancer Driver No 1 intact 70 387 45 45 13
STX5 STX5 Q13190 Syntaxin-5 chr11 Not Cancer Driver No 1 intact 36 147 14 14 0
SYAP1 SYAP1 Q96A49 Synapse-associated protein 1 chrX Not Cancer Driver No 1 intact 31 221 22 22 0
TBK1 TBK1 Q9UHD2 Serine/threonine-protein kinase TBK1 chr12 Not Cancer Driver No 1 intact 101 42 5 5 12
TFG TFG Q92734 Protein TFG chr3 Census, Compendium Yes 1 intact 45 290 34 34 3
TNFRSF6B TNFRSF6B O95407 Tumor necrosis factor receptor superfamily member 6B chr20 Not Cancer Driver No 1 hippie, biogrid 22 22 3 3 0
TOR1AIP1_ENST00000606911 TOR1AIP1 Q5JTV8 Torsin-1A-interacting protein 1 chr1 Not Cancer Driver No 1 intact 71 401 44 44 0
TRIM13_ENST00000378182 TRIM13 O60858 E3 ubiquitin-protein ligase TRIM13 chr13 Not Cancer Driver No 1 intact 53 1 0 0 0
TRMT2A_ENST00000403707 TRMT2A Q8IZ69 tRNA (uracil-5-)-methyltransferase homolog A chr22 Not Cancer Driver No 1 hippie, biogrid 64 157 20 20 0
TYMP_ENST00000395680 TYMP P19971 Thymidine phosphorylase chr22 Not Cancer Driver No 1 hippie, biogrid 28 143 7 7 5
UBIAD1 UBIAD1 Q9Y5Z9 UbiA prenyltransferase domain-containing protein 1 chr1 Not Cancer Driver No 1 intact 46 18 1 1 19
UNC5B UNC5B Q8IZJ1 Netrin receptor UNC5B chr10 Not Cancer Driver No 1 intact 155 117 20 20 0
USO1_ENST00000514213 USO1 O60763 General vesicular transport factor p115 chr4 Not Cancer Driver No 1 intact 78 368 28 28 0
VAPA_ENST00000400000 VAPA Q9P0L0 Vesicle-associated membrane protein-associated protein A chr18 Not Cancer Driver No 1 intact 24 184 14 14 0
VAPB VAPB O95292 Vesicle-associated membrane protein-associated protein B/C chr20 Not Cancer Driver No 1 intact 16 138 8 8 3
VEZT VEZT Q9HBM0 Vezatin chr12 Not Cancer Driver No 1 intact 83 278 22 22 0
VRK2 VRK2 Q86Y07 Serine/threonine-protein kinase VRK2 chr2 Not Cancer Driver No 1 intact 63 126 15 15 0
WDR41 WDR41 Q9HAD4 WD repeat-containing protein 41 chr5 Not Cancer Driver No 1 intact 48 23 2 2 0
WDR6_ENST00000608424 WDR6 Q9NNW5 WD repeat-containing protein 6 chr3 Not Cancer Driver No 1 intact 166 105 13 13 0
YKT6 YKT6 O15498 Synaptobrevin homolog YKT6 chr7 Not Cancer Driver No 1 intact 19 21 2 2 0
YTHDF3_ENST00000539294 YTHDF3 Q7Z739 YTH domain-containing family protein 3 chr8 Not Cancer Driver No 1 intact 74 409 51 51 0
ZNF746_ENST00000340622 ZNF746 Q6NUN9 Zinc finger protein 746 chr7 Not Cancer Driver No 1 hippie 93 436 56 56 0