Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABCE1 | ABCE1 | P61221 | ATP-binding cassette sub-family E member 1 | chr4 | Not Cancer Driver | No | 1 | hippie | 74 | 36 | 6 | 6 | 0 |
| ACP1_ENST00000272065 | ACP1 | P24666 | Low molecular weight phosphotyrosine protein phosphatase | chr2 | Not Cancer Driver | No | 1 | hippie | 28 | 13 | 2 | 2 | 0 |
| ACTA1 | ACTA1 | P68133 | Actin, alpha skeletal muscle | chr1 | Not Cancer Driver | No | 1 | hippie | 70 | 48 | 14 | 14 | 84 |
| ACTB_ENST00000646664 | ACTB | P60709 | Actin, cytoplasmic 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 112 | 43 | 5 | 5 | 5 |
| AK2 | AK2 | P54819 | Adenylate kinase 2, mitochondrial | chr1 | Not Cancer Driver | No | 1 | hippie | 23 | 76 | 12 | 12 | 2 |
| APP | APP | P05067 | Amyloid-beta precursor protein | chr21 | Not Cancer Driver | No | 2 | intact, hippie | 128 | 418 | 71 | 71 | 17 |
| ARF6 | ARF6 | P62330 | ADP-ribosylation factor 6 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 5 | 0 | 0 | 0 |
| ATP5MG | ATP5MG | O75964 | ATP synthase subunit g, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie | 16 | 0 | 0 | 0 | 0 |
| ATP5PO | ATP5PO | P48047 | ATP synthase subunit O, mitochondrial | chr21 | Not Cancer Driver | No | 1 | hippie | 19 | 9 | 2 | 2 | 0 |
| ATP6V1E1 | ATP6V1E1 | P36543 | V-type proton ATPase subunit E 1 | chr22 | Not Cancer Driver | No | 1 | hippie | 27 | 27 | 3 | 3 | 2 |
| AXL | AXL | P30530 | Tyrosine-protein kinase receptor UFO | chr19 | Not Cancer Driver | No | 1 | hippie | 168 | 341 | 64 | 64 | 0 |
| BCAM | BCAM | P50895 | Basal cell adhesion molecule | chr19 | Not Cancer Driver | No | 1 | hippie | 107 | 354 | 74 | 74 | 0 |
| BCAR1_ENST00000162330 | BCAR1 | P56945 | Breast cancer anti-estrogen resistance protein 1 | chr16 | Not Cancer Driver | No | 1 | hippie | 108 | 677 | 75 | 75 | 0 |
| BRD4 | BRD4 | O60885 | Bromodomain-containing protein 4 | chr19 | Census, Compendium | Yes | 1 | hippie | 193 | 1182 | 172 | 172 | 0 |
| C11orf52 | C11orf52 | Q96A22 | Uncharacterized protein C11orf52 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 108 | 12 | 12 | 0 |
| C2CD2 | C2CD2 | Q9Y426 | C2 domain-containing protein 2 | chr21 | Not Cancer Driver | No | 1 | hippie, biogrid | 83 | 385 | 56 | 56 | 0 |
| C2CD2L | C2CD2L | O14523 | Phospholipid transfer protein C2CD2L | chr11 | Not Cancer Driver | No | 1 | hippie | 77 | 491 | 65 | 65 | 0 |
| CA2 | CA2 | P00918 | Carbonic anhydrase 2 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 55 | 8 | 8 | 4 |
| CACYBP | CACYBP | Q9HB71 | Calcyclin-binding protein | chr1 | Not Cancer Driver | No | 1 | hippie | 27 | 92 | 10 | 10 | 0 |
| CALR | CALR | P27797 | Calreticulin | chr19 | Census | Yes | 1 | hippie, biogrid | 45 | 245 | 31 | 31 | 0 |
| CASK_ENST00000378163 | CASK | O14936 | Peripheral plasma membrane protein CASK | chrX | Not Cancer Driver | No | 1 | hippie | 118 | 285 | 45 | 45 | 4 |
| CAV1 | CAV1 | Q03135 | Caveolin-1 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 30 | 2 | 0 | 0 | 0 |
| CBR1 | CBR1 | P16152 | Carbonyl reductase [NADPH] 1 | chr21 | Not Cancer Driver | No | 1 | hippie | 27 | 62 | 11 | 11 | 0 |
| CD44 | CD44 | P16070 | CD44 antigen | chr11 | Not Cancer Driver | No | 1 | hippie | 75 | 542 | 60 | 60 | 0 |
| CDH1 | CDH1 | P12830 | Cadherin-1 | chr16 | Census, Compendium | Yes | 1 | hippie | 150 | 400 | 82 | 82 | 5 |
| CDK2 | CDK2 | P24941 | Cyclin-dependent kinase 2 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 0 | 0 | 0 | 0 |
| CDKN2A_ENST00000304494 | CDKN2A | P42771 | Cyclin-dependent kinase inhibitor 2A | chr9 | Census, Compendium | Yes | 1 | hippie | 166 | 83 | 88 | 88 | 36 |
| CENPJ | CENPJ | Q9HC77 | Centromere protein J | chr13 | Not Cancer Driver | No | 1 | hippie | 176 | 1176 | 158 | 158 | 1 |
| CFAP100 | CFAP100 | Q494V2 | Cilia- and flagella-associated protein 100 | chr3 | Not Cancer Driver | No | 1 | hippie | 115 | 438 | 89 | 89 | 0 |
| CHEK2_ENST00000405598 | CHEK2 | O96017 | Serine/threonine-protein kinase Chk2 | chr22 | Census, Compendium | Yes | 1 | hippie, biogrid | 335 | 157 | 130 | 130 | 13 |
| CIC | CIC | Q96RK0 | Protein capicua homolog | chr19 | Census, Compendium | Yes | 1 | hippie | 276 | 1550 | 266 | 266 | 0 |
| CKMT1B_ENST00000441322 | CKMT1B | P12532 | Creatine kinase U-type, mitochondrial | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 77 | 1 | 1 | 0 |
| CLIC1_ENST00000375779 | CLIC1 | O00299 | Chloride intracellular channel protein 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 32 | 27 | 5 | 5 | 0 |
| CLNS1A_ENST00000528364 | CLNS1A | P54105 | Methylosome subunit pICln | chr11 | Not Cancer Driver | No | 1 | hippie | 19 | 170 | 13 | 13 | 0 |
| COPZ1_ENST00000262061 | COPZ1 | P61923 | Coatomer subunit zeta-1 | chr12 | Not Cancer Driver | No | 1 | hippie | 20 | 0 | 0 | 0 | 0 |
| COX5B | COX5B | P10606 | Cytochrome c oxidase subunit 5B, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie | 16 | 58 | 6 | 6 | 0 |
| CRYAB_ENST00000616970 | CRYAB | P02511 | Alpha-crystallin B chain | chr11 | Not Cancer Driver | No | 1 | hippie | 22 | 59 | 11 | 11 | 4 |
| CSTB | CSTB | P04080 | Cystatin-B | chr21 | Not Cancer Driver | No | 1 | hippie | 7 | 40 | 0 | 0 | 1 |
| CYCS_ENST00000409409 | CYCS | P99999 | Cytochrome c | chr7 | Not Cancer Driver | No | 1 | hippie | 12 | 19 | 3 | 3 | 1 |
| DAD1 | DAD1 | P61803 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 | chr14 | Not Cancer Driver | No | 1 | hippie | 7 | 0 | 0 | 0 | 0 |
| DCAF15 | DCAF15 | Q66K64 | DDB1- and CUL4-associated factor 15 | chr19 | Not Cancer Driver | No | 1 | hippie | 50 | 173 | 18 | 18 | 0 |
| DCTN1 | DCTN1 | Q14203 | Dynactin subunit 1 | chr2 | Census | Yes | 1 | hippie | 172 | 817 | 111 | 111 | 11 |
| DHX9 | DHX9 | Q08211 | ATP-dependent RNA helicase A | chr1 | Compendium | Yes | 1 | hippie | 182 | 331 | 42 | 42 | 0 |
| DLG1_ENST00000419354 | DLG1 | Q12959 | Disks large homolog 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 120 | 460 | 67 | 67 | 0 |
| DRD2_ENST00000542968 | DRD2 | P14416 | D(2) dopamine receptor | chr11 | Not Cancer Driver | No | 1 | hippie | 127 | 124 | 45 | 45 | 0 |
| DRD3_ENST00000460779 | DRD3 | P35462 | D(3) dopamine receptor | chr3 | Not Cancer Driver | No | 1 | hippie | 88 | 45 | 17 | 17 | 0 |
| DYNC1H1 | DYNC1H1 | Q14204 | Cytoplasmic dynein 1 heavy chain 1 | chr14 | Not Cancer Driver | No | 1 | hippie | 505 | 495 | 62 | 62 | 21 |
| DYNC1LI2 | DYNC1LI2 | O43237 | Cytoplasmic dynein 1 light intermediate chain 2 | chr16 | Not Cancer Driver | No | 1 | hippie | 43 | 211 | 14 | 14 | 0 |
| DYNLL1_ENST00000242577 | DYNLL1 | P63167 | Dynein light chain 1, cytoplasmic | chr12 | Not Cancer Driver | No | 1 | hippie | 9 | 0 | 0 | 0 | 0 |
| DYNLRB1 | DYNLRB1 | Q9NP97 | Dynein light chain roadblock-type 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 23 | 19 | 4 | 4 | 0 |
| ECHS1 | ECHS1 | P30084 | Enoyl-CoA hydratase, mitochondrial | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 7 | 1 | 1 | 14 |
| EEF1B2_ENST00000236957 | EEF1B2 | P24534 | Elongation factor 1-beta | chr2 | Not Cancer Driver | No | 1 | hippie | 63 | 71 | 11 | 11 | 0 |
| EEF2K | EEF2K | O00418 | Eukaryotic elongation factor 2 kinase | chr16 | Not Cancer Driver | No | 2 | hippie, biogrid | 104 | 311 | 39 | 39 | 0 |
| EGFR | EGFR | P00533 | Epidermal growth factor receptor | chr7 | Census, Compendium | Yes | 1 | hippie | 444 | 223 | 35 | 35 | 1 |
| EIF1 | EIF1 | P41567 | Eukaryotic translation initiation factor 1 | chr17 | Not Cancer Driver | No | 1 | hippie | 13 | 9 | 1 | 1 | 0 |
| EIF3G | EIF3G | O75821 | Eukaryotic translation initiation factor 3 subunit G | chr19 | Not Cancer Driver | No | 1 | hippie | 41 | 233 | 30 | 30 | 0 |
| EIF4G1_ENST00000346169 | EIF4G1 | Q04637 | Eukaryotic translation initiation factor 4 gamma 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 229 | 1079 | 153 | 153 | 2 |
| ELOC | ELOC | Q15369 | Elongin-C | chr8 | Not Cancer Driver | No | 1 | hippie | 22 | 25 | 5 | 5 | 0 |
| EPB41L1 | EPB41L1 | Q9H4G0 | Band 4.1-like protein 1 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 151 | 577 | 109 | 109 | 1 |
| EPB41L3 | EPB41L3 | Q9Y2J2 | Band 4.1-like protein 3 | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 298 | 695 | 207 | 207 | 0 |
| EPB42_ENST00000441366 | EPB42 | P16452 | Protein 4.2 | chr15 | Not Cancer Driver | No | 1 | hippie | 94 | 113 | 10 | 10 | 4 |
| ESR1_ENST00000206249 | ESR1 | P03372 | Estrogen receptor | chr6 | Census, Compendium | Yes | 1 | hippie | 121 | 195 | 27 | 27 | 2 |
| ESR2 | ESR2 | Q92731 | Estrogen receptor beta | chr14 | Not Cancer Driver | No | 1 | hippie | 90 | 92 | 11 | 11 | 1 |
| EZR | EZR | P15311 | Ezrin | chr6 | Census | Yes | 1 | hippie | 66 | 295 | 35 | 35 | 0 |
| FABP5 | FABP5 | Q01469 | Fatty acid-binding protein 5 | chr8 | Not Cancer Driver | No | 1 | hippie | 15 | 4 | 4 | 4 | 0 |
| FHL1_ENST00000345434 | FHL1 | Q13642 | Four and a half LIM domains protein 1 | chrX | Not Cancer Driver | No | 1 | hippie | 56 | 51 | 7 | 7 | 13 |
| FKBP1A | FKBP1A | P62942 | Peptidyl-prolyl cis-trans isomerase FKBP1A | chr20 | Not Cancer Driver | No | 1 | hippie | 15 | 39 | 7 | 7 | 0 |
| FKBP2_ENST00000449942 | FKBP2 | P26885 | Peptidyl-prolyl cis-trans isomerase FKBP2 | chr11 | Not Cancer Driver | No | 1 | hippie | 15 | 20 | 1 | 1 | 0 |
| FLOT1 | FLOT1 | O75955 | Flotillin-1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 122 | 15 | 15 | 0 |
| FN1 | FN1 | P02751 | Fibronectin | chr2 | Compendium | Yes | 1 | hippie | 394 | 1243 | 185 | 185 | 8 |
| GBF1 | GBF1 | Q92538 | Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 | chr10 | Not Cancer Driver | No | 1 | hippie | 216 | 669 | 76 | 76 | 0 |
| GDI1 | GDI1 | P31150 | Rab GDP dissociation inhibitor alpha | chrX | Not Cancer Driver | No | 1 | hippie | 69 | 34 | 6 | 6 | 2 |
| GOT2 | GOT2 | P00505 | Aspartate aminotransferase, mitochondrial | chr16 | Not Cancer Driver | No | 1 | hippie | 61 | 25 | 3 | 3 | 1 |
| GRIA4_ENST00000530497 | GRIA4 | P48058 | Glutamate receptor 4 | chr11 | Not Cancer Driver | No | 1 | hippie | 227 | 63 | 25 | 25 | 4 |
| GYPC | GYPC | P04921 | Glycophorin-C | chr2 | Not Cancer Driver | No | 1 | hippie | 32 | 73 | 18 | 18 | 0 |
| HADHA | HADHA | P40939 | Trifunctional enzyme subunit alpha, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie | 72 | 19 | 2 | 2 | 5 |
| HIGD1A_ENST00000418900 | HIGD1A | Q9Y241 | HIG1 domain family member 1A, mitochondrial | chr3 | Not Cancer Driver | No | 1 | hippie | 17 | 8 | 0 | 0 | 0 |
| HNRNPL | HNRNPL | P14866 | Heterogeneous nuclear ribonucleoprotein L | chr19 | Not Cancer Driver | No | 1 | hippie | 89 | 283 | 29 | 29 | 0 |
| HPRT1 | HPRT1 | P00492 | Hypoxanthine-guanine phosphoribosyltransferase | chrX | Not Cancer Driver | No | 1 | hippie | 22 | 3 | 0 | 0 | 62 |
| HRAS | HRAS | P01112 | GTPase HRas | chr11 | Census, Compendium | Yes | 1 | hippie | 107 | 16 | 4 | 4 | 18 |
| HSPE1 | HSPE1 | P61604 | 10 kDa heat shock protein, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie | 8 | 3 | 0 | 0 | 0 |
| HTT | HTT | P42858 | Huntingtin | chr4 | Not Cancer Driver | No | 1 | hippie | 336 | 666 | 69 | 69 | 2 |
| KDM4C | KDM4C | Q9H3R0 | Lysine-specific demethylase 4C | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 124 | 309 | 40 | 40 | 0 |
| KPNA2_ENST00000330459 | KPNA2 | P52292 | Importin subunit alpha-1 | chr17 | Not Cancer Driver | No | 1 | hippie | 74 | 129 | 18 | 18 | 0 |
| KRAS | KRAS | P01116 | GTPase KRas | chr12 | Census, Compendium | Yes | 1 | hippie, biogrid | 788 | 7 | 2 | 2 | 27 |
| KRT222 | KRT222 | Q8N1A0 | Keratin-like protein KRT222 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 132 | 18 | 18 | 0 |
| LAMP1 | LAMP1 | P11279 | Lysosome-associated membrane glycoprotein 1 | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 47 | 93 | 10 | 10 | 0 |
| LRPPRC | LRPPRC | P42704 | Leucine-rich PPR motif-containing protein, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie | 131 | 18 | 2 | 2 | 1 |
| LRRC59 | LRRC59 | Q96AG4 | Leucine-rich repeat-containing protein 59 | chr17 | Not Cancer Driver | No | 1 | hippie | 33 | 122 | 15 | 15 | 0 |
| LRRK2 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | Not Cancer Driver | No | 1 | hippie | 519 | 90 | 17 | 17 | 23 |
| LYN | LYN | P07948 | Tyrosine-protein kinase Lyn | chr8 | Census | Yes | 1 | hippie, biogrid | 95 | 84 | 12 | 12 | 0 |
| MACROD1 | MACROD1 | Q9BQ69 | ADP-ribose glycohydrolase MACROD1 | chr11 | Not Cancer Driver | No | 1 | hippie | 24 | 45 | 1 | 1 | 0 |
| MAPRE1 | MAPRE1 | Q15691 | Microtubule-associated protein RP/EB family member 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 26 | 109 | 11 | 11 | 0 |
| MARCKS | MARCKS | P29966 | Myristoylated alanine-rich C-kinase substrate | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 14 | 328 | 14 | 14 | 0 |
| MED4 | MED4 | Q9NPJ6 | Mediator of RNA polymerase II transcription subunit 4 | chr13 | Not Cancer Driver | No | 1 | hippie | 29 | 161 | 17 | 17 | 0 |
| MIF | MIF | P14174 | Macrophage migration inhibitory factor | chr22 | Not Cancer Driver | No | 1 | hippie | 4 | 0 | 0 | 0 | 0 |
| MRPL57 | MRPL57 | Q9BQC6 | Ribosomal protein 63, mitochondrial | chr13 | Not Cancer Driver | No | 1 | hippie | 11 | 9 | 1 | 1 | 0 |
| MTPN | MTPN | P58546 | Myotrophin | chr7 | Not Cancer Driver | No | 1 | hippie | 11 | 11 | 3 | 3 | 0 |
| MYH1 | MYH1 | P12882 | Myosin-1 | chr17 | Not Cancer Driver | No | 1 | hippie | 546 | 1153 | 335 | 335 | 0 |
| MYH10_ENST00000269243 | MYH10 | P35580 | Myosin-10 | chr17 | Not Cancer Driver | No | 1 | hippie | 258 | 1134 | 136 | 136 | 0 |
| MYH9 | MYH9 | P35579 | Myosin-9 | chr22 | Census, Compendium | Yes | 1 | hippie, biogrid | 310 | 1120 | 160 | 160 | 17 |
| NAA40 | NAA40 | Q86UY6 | N-alpha-acetyltransferase 40 | chr11 | Not Cancer Driver | No | 1 | hippie | 22 | 30 | 3 | 3 | 0 |
| NPPA | NPPA | P01160 | Natriuretic peptides A | chr1 | Not Cancer Driver | No | 1 | hippie | 32 | 71 | 14 | 14 | 1 |
| NRAS | NRAS | P01111 | GTPase NRas | chr1 | Census, Compendium | Yes | 1 | hippie | 284 | 10 | 0 | 0 | 14 |
| NSD3 | NSD3 | Q9BZ95 | Histone-lysine N-methyltransferase NSD3 | chr8 | Census | Yes | 1 | hippie | 164 | 679 | 98 | 98 | 0 |
| NTRK1 | NTRK1 | P04629 | High affinity nerve growth factor receptor | chr1 | Census, Compendium | Yes | 1 | hippie | 168 | 57 | 8 | 8 | 25 |
| NUMA1 | NUMA1 | Q14980 | Nuclear mitotic apparatus protein 1 | chr11 | Census, Compendium | Yes | 1 | hippie | 234 | 1864 | 203 | 203 | 0 |
| NUP155 | NUP155 | O75694 | Nuclear pore complex protein Nup155 | chr5 | Not Cancer Driver | No | 1 | hippie | 154 | 221 | 19 | 19 | 1 |
| OCLN | OCLN | Q16625 | Occludin | chr5 | Not Cancer Driver | No | 1 | biogrid | 54 | 244 | 21 | 21 | 1 |
| OPTN_ENST00000263036 | OPTN | Q96CV9 | Optineurin | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 470 | 51 | 51 | 6 |
| PAFAH1B2 | PAFAH1B2 | P68402 | Platelet-activating factor acetylhydrolase IB subunit alpha2 | chr11 | Census | Yes | 1 | hippie | 25 | 43 | 1 | 1 | 0 |
| PAICS_ENST00000512576 | PAICS | P22234 | Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 35 | 3 | 3 | 0 |
| PCBD1 | PCBD1 | P61457 | Pterin-4-alpha-carbinolamine dehydratase | chr10 | Not Cancer Driver | No | 1 | hippie | 8 | 7 | 0 | 0 | 3 |
| PCMT1_ENST00000464889 | PCMT1 | A0A0A0MRJ6 | Protein-L-isoaspartate O-methyltransferase | chr6 | Not Cancer Driver | No | 1 | hippie | 34 | 38 | 4 | 4 | 0 |
| PCNA | PCNA | P12004 | Proliferating cell nuclear antigen | chr20 | Not Cancer Driver | No | 1 | hippie | 30 | 22 | 3 | 3 | 1 |
| PEBP1 | PEBP1 | P30086 | Phosphatidylethanolamine-binding protein 1 | chr12 | Not Cancer Driver | No | 1 | hippie | 23 | 76 | 13 | 13 | 0 |
| PFAS | PFAS | O15067 | Phosphoribosylformylglycinamidine synthase | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 157 | 380 | 36 | 36 | 0 |
| PFN2 | PFN2 | P35080 | Profilin-2 | chr3 | Not Cancer Driver | No | 1 | hippie | 20 | 0 | 0 | 0 | 0 |
| PHB2 | PHB2 | Q99623 | Prohibitin-2 | chr12 | Not Cancer Driver | No | 1 | hippie | 31 | 26 | 4 | 4 | 0 |
| PIN1 | PIN1 | Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 17 | 115 | 12 | 12 | 0 |
| PIN4 | PIN4 | Q9Y237-2 | Isoform 2 of Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 | chrX | Not Cancer Driver | No | 1 | hippie | 19 | 115 | 11 | 11 | 0 |
| PLEKHA4 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 136 | 687 | 128 | 128 | 0 |
| PNP | PNP | P00491 | Purine nucleoside phosphorylase | chr14 | Not Cancer Driver | No | 1 | hippie | 38 | 29 | 2 | 2 | 5 |
| PRKCB_ENST00000321728 | PRKCB | P05771 | Protein kinase C beta type | chr16 | Census, Compendium | Yes | 1 | hippie | 205 | 148 | 40 | 40 | 0 |
| PSMA1_ENST00000396394 | PSMA1 | P25786 | Proteasome subunit alpha type-1 | chr11 | Not Cancer Driver | No | 1 | hippie | 48 | 51 | 9 | 9 | 0 |
| PSMA6 | PSMA6 | P60900 | Proteasome subunit alpha type-6 | chr14 | Not Cancer Driver | No | 1 | hippie | 37 | 2 | 1 | 1 | 0 |
| PSMA7 | PSMA7 | O14818 | Proteasome subunit alpha type-7 | chr20 | Not Cancer Driver | No | 1 | hippie | 24 | 23 | 1 | 1 | 0 |
| PSMB1 | PSMB1 | P20618 | Proteasome subunit beta type-1 | chr6 | Not Cancer Driver | No | 1 | hippie | 25 | 14 | 2 | 2 | 0 |
| PSMB5 | PSMB5 | P28074 | Proteasome subunit beta type-5 | chr14 | Not Cancer Driver | No | 1 | hippie | 39 | 9 | 0 | 0 | 0 |
| PSMB7 | PSMB7 | Q99436 | Proteasome subunit beta type-7 | chr9 | Not Cancer Driver | No | 1 | hippie | 25 | 26 | 3 | 3 | 0 |
| PSMC4 | PSMC4 | P43686 | 26S proteasome regulatory subunit 6B | chr19 | Not Cancer Driver | No | 1 | hippie | 51 | 21 | 3 | 3 | 0 |
| PSME3_ENST00000590720 | PSME3 | P61289 | Proteasome activator complex subunit 3 | chr17 | Not Cancer Driver | No | 1 | hippie | 20 | 25 | 5 | 5 | 0 |
| RAB10 | RAB10 | P61026 | Ras-related protein Rab-10 | chr2 | Not Cancer Driver | No | 1 | hippie | 19 | 28 | 2 | 2 | 0 |
| RAB11B | RAB11B | Q15907 | Ras-related protein Rab-11B | chr19 | Not Cancer Driver | No | 1 | hippie | 26 | 39 | 3 | 3 | 2 |
| RAB2A | RAB2A | P61019 | Ras-related protein Rab-2A | chr8 | Not Cancer Driver | No | 1 | hippie | 22 | 58 | 4 | 4 | 0 |
| RAB35 | RAB35 | Q15286 | Ras-related protein Rab-35 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 25 | 2 | 2 | 0 |
| RAB5C_ENST00000393860 | RAB5C | P51148 | Ras-related protein Rab-5C | chr17 | Not Cancer Driver | No | 1 | hippie | 24 | 50 | 4 | 4 | 0 |
| RAB8A | RAB8A | P61006 | Ras-related protein Rab-8A | chr19 | Not Cancer Driver | No | 1 | hippie | 37 | 26 | 3 | 3 | 0 |
| RANBP1_ENST00000331821 | RANBP1 | P43487 | Ran-specific GTPase-activating protein | chr22 | Not Cancer Driver | No | 1 | hippie | 19 | 137 | 16 | 16 | 0 |
| RHOD | RHOD | O00212 | Rho-related GTP-binding protein RhoD | chr11 | Not Cancer Driver | No | 1 | hippie | 20 | 10 | 0 | 0 | 0 |
| RHOF | RHOF | Q9HBH0 | Rho-related GTP-binding protein RhoF | chr12 | Not Cancer Driver | No | 1 | hippie | 18 | 10 | 0 | 0 | 0 |
| RHOG_ENST00000396978 | RHOG | P84095 | Rho-related GTP-binding protein RhoG | chr11 | Not Cancer Driver | No | 1 | hippie | 26 | 22 | 5 | 5 | 0 |
| RNPS1_ENST00000301730 | RNPS1 | Q15287 | RNA-binding protein with serine-rich domain 1 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 30 | 305 | 30 | 30 | 0 |
| RPL38_ENST00000439590 | RPL38 | P63173 | 60S ribosomal protein L38 | chr17 | Not Cancer Driver | No | 1 | hippie | 2 | 9 | 0 | 0 | 0 |
| RPS21 | RPS21 | P63220 | 40S ribosomal protein S21 | chr20 | Not Cancer Driver | No | 1 | hippie | 8 | 0 | 0 | 0 | 0 |
| RPS3A | RPS3A | P61247 | 40S ribosomal protein S3a | chr4 | Compendium | Yes | 1 | hippie | 21 | 85 | 5 | 5 | 0 |
| RWDD2B | RWDD2B | P57060 | RWD domain-containing protein 2B | chr21 | Not Cancer Driver | No | 1 | hippie | 38 | 41 | 0 | 0 | 0 |
| S100A11 | S100A11 | P31949 | Protein S100-A11 | chr1 | Not Cancer Driver | No | 1 | hippie | 13 | 14 | 2 | 2 | 0 |
| SAR1A_ENST00000373238 | SAR1A | Q9NR31 | GTP-binding protein SAR1a | chr10 | Not Cancer Driver | No | 1 | hippie | 23 | 4 | 0 | 0 | 0 |
| SCP2 | SCP2 | P22307 | Sterol carrier protein 2 | chr1 | Not Cancer Driver | No | 1 | hippie | 59 | 45 | 2 | 2 | 0 |
| SEC14L1_ENST00000436233 | SEC14L1 | Q92503 | SEC14-like protein 1 | chr17 | Not Cancer Driver | No | 1 | hippie | 104 | 82 | 16 | 16 | 0 |
| SEC62 | SEC62 | Q99442 | Translocation protein SEC62 | chr3 | Not Cancer Driver | No | 1 | hippie | 41 | 211 | 23 | 23 | 0 |
| SF1_ENST00000377390 | SF1 | Q15637 | Splicing factor 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 110 | 627 | 106 | 106 | 0 |
| SF3A1 | SF3A1 | Q15459 | Splicing factor 3A subunit 1 | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 82 | 631 | 67 | 67 | 0 |
| SF3A3 | SF3A3 | Q12874 | Splicing factor 3A subunit 3 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 63 | 182 | 19 | 19 | 0 |
| SLC4A1 | SLC4A1 | P02730 | Band 3 anion transport protein | chr17 | Not Cancer Driver | No | 1 | hippie | 153 | 130 | 23 | 23 | 39 |
| SLIRP | SLIRP | Q9GZT3 | SRA stem-loop-interacting RNA-binding protein, mitochondrial | chr14 | Not Cancer Driver | No | 1 | hippie | 7 | 41 | 3 | 3 | 0 |
| SMAD3 | SMAD3 | P84022 | Mothers against decapentaplegic homolog 3 | chr15 | Census, Compendium | Yes | 1 | hippie | 97 | 111 | 19 | 19 | 5 |
| SNRNP200 | SNRNP200 | O75643 | U5 small nuclear ribonucleoprotein 200 kDa helicase | chr2 | Not Cancer Driver | No | 1 | hippie | 237 | 270 | 37 | 37 | 11 |
| SNU13_ENST00000355257 | SNU13 | P55769 | NHP2-like protein 1 | chr22 | Not Cancer Driver | No | 1 | hippie | 17 | 2 | 0 | 0 | 0 |
| SNX3 | SNX3 | O60493 | Sorting nexin-3 | chr6 | Not Cancer Driver | No | 1 | hippie | 21 | 37 | 4 | 4 | 0 |
| SPTAN1_ENST00000372731 | SPTAN1 | Q13813 | Spectrin alpha chain, non-erythrocytic 1 | chr9 | Not Cancer Driver | No | 1 | hippie | 315 | 980 | 114 | 114 | 0 |
| SPTBN1 | SPTBN1 | Q01082 | Spectrin beta chain, non-erythrocytic 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 311 | 869 | 123 | 123 | 0 |
| SPTB_ENST00000389721 | SPTB | P11277 | Spectrin beta chain, erythrocytic | chr14 | Not Cancer Driver | No | 1 | hippie | 328 | 562 | 70 | 70 | 7 |
| STIP1_ENST00000305218 | STIP1 | P31948 | Stress-induced-phosphoprotein 1 | chr11 | Not Cancer Driver | No | 1 | hippie | 74 | 270 | 39 | 39 | 0 |
| STX6 | STX6 | O43752 | Syntaxin-6 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 33 | 78 | 11 | 11 | 0 |
| TAGLN2_ENST00000368097 | TAGLN2 | P37802 | Transgelin-2 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 83 | 12 | 12 | 0 |
| TGOLN2_ENST00000377386 | TGOLN2 | O43493 | Trans-Golgi network integral membrane protein 2 | chr2 | Not Cancer Driver | No | 1 | hippie | 51 | 399 | 46 | 46 | 0 |
| TIMM13 | TIMM13 | Q9Y5L4 | Mitochondrial import inner membrane translocase subunit Tim13 | chr19 | Not Cancer Driver | No | 1 | hippie | 7 | 20 | 1 | 1 | 0 |
| TJP2_ENST00000377245 | TJP2 | Q9UDY2 | Tight junction protein ZO-2 | chr9 | Not Cancer Driver | No | 1 | hippie | 149 | 919 | 113 | 113 | 1 |
| TMEM33_ENST00000325094 | TMEM33 | P57088 | Transmembrane protein 33 | chr4 | Not Cancer Driver | No | 1 | hippie | 24 | 6 | 0 | 0 | 0 |
| TMOD1_ENST00000395211 | TMOD1 | P28289 | Tropomodulin-1 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 195 | 29 | 29 | 0 |
| TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | Census, Compendium | Yes | 1 | hippie | 2891 | 282 | 1466 | 1466 | 83 |
| TPM1_ENST00000403994 | TPM1 | P09493 | Tropomyosin alpha-1 chain | chr15 | Not Cancer Driver | No | 1 | hippie | 33 | 234 | 29 | 29 | 8 |
| TPM2 | TPM2 | P07951 | Tropomyosin beta chain | chr9 | Not Cancer Driver | No | 1 | hippie | 39 | 232 | 35 | 35 | 15 |
| TPT1_ENST00000530705 | TPT1 | P13693 | Translationally-controlled tumor protein | chr13 | Not Cancer Driver | No | 1 | hippie | 17 | 43 | 6 | 6 | 0 |
| TRIM25 | TRIM25 | Q14258 | E3 ubiquitin/ISG15 ligase TRIM25 | chr17 | Not Cancer Driver | No | 1 | hippie | 59 | 225 | 20 | 20 | 0 |
| TRMT112 | TRMT112 | Q9UI30 | Multifunctional methyltransferase subunit TRM112-like protein | chr11 | Not Cancer Driver | No | 1 | hippie | 15 | 17 | 2 | 2 | 0 |
| TSN | TSN | Q15631 | Translin | chr2 | Not Cancer Driver | No | 1 | hippie | 30 | 0 | 0 | 0 | 0 |
| TUBA4A | TUBA4A | P68366 | Tubulin alpha-4A chain | chr2 | Not Cancer Driver | No | 1 | hippie | 73 | 39 | 4 | 4 | 5 |
| TUFM | TUFM | P49411 | Elongation factor Tu, mitochondrial | chr16 | Not Cancer Driver | No | 1 | hippie | 51 | 50 | 3 | 3 | 1 |
| TXN | TXN | P10599 | Thioredoxin | chr9 | Not Cancer Driver | No | 1 | hippie | 6 | 0 | 0 | 0 | 0 |
| TXNDC17 | TXNDC17 | Q9BRA2 | Thioredoxin domain-containing protein 17 | chr17 | Not Cancer Driver | No | 1 | hippie | 8 | 0 | 0 | 0 | 0 |
| U2AF1 | U2AF1 | Q01081 | Splicing factor U2AF 35 kDa subunit | chr21 | Census, Compendium | Yes | 1 | hippie | 70 | 73 | 13 | 13 | 3 |
| U2AF2 | U2AF2 | P26368 | Splicing factor U2AF 65 kDa subunit | chr19 | Compendium | Yes | 1 | hippie | 78 | 191 | 28 | 28 | 0 |
| UBE2L3_ENST00000342192 | UBE2L3 | P68036 | Ubiquitin-conjugating enzyme E2 L3 | chr22 | Not Cancer Driver | No | 1 | hippie | 19 | 32 | 4 | 4 | 0 |
| UBE2M | UBE2M | P61081 | NEDD8-conjugating enzyme Ubc12 | chr19 | Not Cancer Driver | No | 1 | hippie | 30 | 32 | 6 | 6 | 0 |
| UFL1 | UFL1 | O94874 | E3 UFM1-protein ligase 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 109 | 141 | 24 | 24 | 0 |
| VAMP3 | VAMP3 | Q15836 | Vesicle-associated membrane protein 3 | chr1 | Not Cancer Driver | No | 1 | hippie | 11 | 17 | 1 | 1 | 0 |
| WWC1_ENST00000265293 | WWC1 | Q8IX03 | Protein KIBRA | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 147 | 550 | 81 | 81 | 0 |
| YWHAB_ENST00000353703 | YWHAB | P31946 | 14-3-3 protein beta/alpha | chr20 | Not Cancer Driver | No | 1 | hippie | 22 | 109 | 4 | 4 | 0 |
| YWHAG | YWHAG | P61981 | 14-3-3 protein gamma | chr7 | Not Cancer Driver | No | 2 | hippie, biogrid | 26 | 77 | 9 | 9 | 2 |
| YWHAQ | YWHAQ | P27348 | 14-3-3 protein theta | chr2 | Not Cancer Driver | No | 1 | hippie | 29 | 41 | 6 | 6 | 0 |
| ZCCHC10 | ZCCHC10 | Q8TBK6 | Zinc finger CCHC domain-containing protein 10 | chr5 | Not Cancer Driver | No | 1 | hippie | 12 | 144 | 11 | 11 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|