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ENO1 ,ENO1 ,P06733
  • Uniprot Accession= P06733
  • Ensembl Transcript= ENST00000646539.1
  • Uniprot Name= ENO1
  • Name= Alpha-enolase
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 76
  • Number of Interaction partner in biogrid: 108
  • Number of Interaction partner in hippie: 490
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
AAR2_ENST00000320849 AAR2 Q9Y312 Protein AAR2 homolog chr20 Not Cancer Driver No 1 hippie 56 28 6 6 0
ABAT_ENST00000268251 ABAT P80404 4-aminobutyrate aminotransferase, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 84 28 5 5 1
ABI2_ENST00000261018 ABI2 Q9NYB9 Abl interactor 2 chr2 Not Cancer Driver No 1 hippie 56 361 38 38 0
ACAA1 ACAA1 P09110 3-ketoacyl-CoA thiolase, peroxisomal chr3 Not Cancer Driver No 1 hippie, biogrid 37 116 8 8 0
ACAA2 ACAA2 P42765 3-ketoacyl-CoA thiolase, mitochondrial chr18 Not Cancer Driver No 1 hippie, biogrid 42 51 2 2 0
ACHE_ENST00000241069 ACHE P22303 Acetylcholinesterase chr7 Not Cancer Driver No 1 intact, hippie 81 64 8 8 0
ACO1_ENST00000541043 ACO1 P21399 Cytoplasmic aconitate hydratase chr9 Not Cancer Driver No 1 hippie 108 44 14 14 0
ACO2 ACO2 Q99798 Aconitate hydratase, mitochondrial chr22 Not Cancer Driver No 1 hippie, biogrid 94 172 19 19 5
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 1 intact, hippie 112 43 5 5 5
AGR2 AGR2 O95994 Anterior gradient protein 2 homolog chr7 Not Cancer Driver No 1 hippie 23 20 2 2 0
AGRN AGRN O00468 Agrin chr1 Not Cancer Driver No 1 hippie 188 490 40 40 5
AGTPBP1_ENST00000357081 AGTPBP1 Q9UPW5 Cytosolic carboxypeptidase 1 chr9 Not Cancer Driver No 1 intact, hippie 158 321 42 42 4
AHSA1 AHSA1 O95433 Activator of 90 kDa heat shock protein ATPase homolog 1 chr14 Not Cancer Driver No 1 hippie 46 146 17 17 0
AK4 AK4 P27144 Adenylate kinase 4, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 26 24 3 3 0
AKR1B1 AKR1B1 P15121 Aldo-keto reductase family 1 member B1 chr7 Not Cancer Driver No 1 hippie, biogrid 52 19 1 1 0
AKR1B15 AKR1B15 C9JRZ8-2 Isoform 2 of Aldo-keto reductase family 1 member B15 chr7 Not Cancer Driver No 1 hippie, biogrid 71 56 9 9 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 Census, Compendium Yes 1 hippie 108 158 24 24 4
AKTIP_ENST00000570004 AKTIP Q9H8T0 AKT-interacting protein chr16 Not Cancer Driver No 1 hippie 33 95 10 10 0
ALDH4A1 ALDH4A1 P30038 Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 63 46 9 9 1
ALDOA_ENST00000643777 ALDOA P04075 Fructose-bisphosphate aldolase A chr16 Not Cancer Driver No 2 hippie, biogrid 47 65 9 9 3
AMBP AMBP P02760 Protein AMBP chr9 Not Cancer Driver No 1 hippie 57 61 15 15 0
ANKRD40 ANKRD40 Q6AI12 Ankyrin repeat domain-containing protein 40 chr17 Not Cancer Driver No 1 hippie 43 204 28 28 0
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 Not Cancer Driver No 1 hippie 59 61 12 12 0
AR AR P10275 Androgen receptor chrX Census, Compendium Yes 1 hippie 196 443 88 88 169
ARAF_ENST00000377045 ARAF P10398 Serine/threonine-protein kinase A-Raf chrX Census, Compendium Yes 1 hippie 84 181 32 32 0
ARCN1 ARCN1 P48444 Coatomer subunit delta chr11 Not Cancer Driver No 1 hippie, biogrid 46 194 24 24 0
ARF1_ENST00000272102 ARF1 P84077 ADP-ribosylation factor 1 chr1 Not Cancer Driver No 1 intact 30 4 2 2 2
ARID1B_ENST00000350026 ARID1B Q8NFD5 AT-rich interactive domain-containing protein 1B chr6 Census, Compendium Yes 1 hippie 251 1890 206 206 0
ARPC4_ENST00000397261 ARPC4 P59998 Actin-related protein 2/3 complex subunit 4 chr3 Not Cancer Driver No 1 hippie 11 3 0 0 0
ASCC3 ASCC3 Q8N3C0 Activating signal cointegrator 1 complex subunit 3 chr6 Not Cancer Driver No 1 hippie 279 87 8 8 0
ASXL1_ENST00000613218 ASXL1 Q8IXJ9 Polycomb group protein ASXL1 chr20 Census, Compendium Yes 1 hippie 205 1300 174 174 0
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 Not Cancer Driver No 1 intact, hippie 65 451 58 58 0
ATG16L1 ATG16L1 Q676U5 Autophagy-related protein 16-1 chr2 Not Cancer Driver No 1 hippie 79 239 25 25 1
ATOH1 ATOH1 Q92858 Transcription factor ATOH1 chr4 Not Cancer Driver No 1 hippie 63 327 55 55 0
ATP5PF_ENST00000400090 ATP5PF P18859 ATP synthase-coupling factor 6, mitochondrial chr21 Not Cancer Driver No 1 hippie 14 15 1 1 0
ATP6AP2 ATP6AP2 O75787 Renin receptor chrX Not Cancer Driver No 1 intact, hippie 56 0 0 0 2
ATXN3 ATXN3 P54252 Ataxin-3 chr14 Not Cancer Driver No 1 hippie 46 181 24 24 0
BCAP31_ENST00000345046 BCAP31 P51572 B-cell receptor-associated protein 31 chrX Not Cancer Driver No 1 hippie 37 104 14 14 0
BCL6_ENST00000232014 BCL6 P41182 B-cell lymphoma 6 protein chr3 Census, Compendium Yes 1 hippie 134 328 67 67 0
BHLHE40 BHLHE40 O14503 Class E basic helix-loop-helix protein 40 chr3 Not Cancer Driver No 1 intact, hippie 52 242 31 31 0
BIN1 BIN1 O00499 Myc box-dependent-interacting protein 1 chr2 Not Cancer Driver No 1 hippie 65 456 42 42 5
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 224 1458 174 174 35
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 193 1182 172 172 0
BRD7_ENST00000394688 BRD7 Q9NPI1 Bromodomain-containing protein 7 chr16 Compendium Yes 1 hippie 82 482 57 57 0
BTF3 BTF3 P20290 Transcription factor BTF3 chr5 Not Cancer Driver No 1 hippie 27 192 24 24 0
BTRC BTRC Q9Y297 F-box/WD repeat-containing protein 1A chr10 Not Cancer Driver No 1 hippie 80 45 4 4 0
C1orf198 C1orf198 Q9H425 Uncharacterized protein C1orf198 chr1 Not Cancer Driver No 1 hippie, biogrid 40 303 36 36 0
C8orf33 C8orf33 Q9H7E9 UPF0488 protein C8orf33 chr8 Not Cancer Driver No 1 hippie 34 172 26 26 0
CALM1 CALM1 P0DP23 Calmodulin-1 chr14 Not Cancer Driver No 1 hippie, biogrid 19 115 15 15 7
CALR CALR P27797 Calreticulin chr19 Census Yes 1 hippie, biogrid 45 245 31 31 0
CAND1 CAND1 Q86VP6 Cullin-associated NEDD8-dissociated protein 1 chr12 Not Cancer Driver No 1 hippie 161 88 7 7 0
CAT CAT P04040 Catalase chr11 Not Cancer Driver No 2 hippie, biogrid 70 176 18 18 0
CBX5 CBX5 P45973 Chromobox protein homolog 5 chr12 Not Cancer Driver No 1 intact, hippie 21 116 12 12 0
CCDC65 CCDC65 Q8IXS2 Dynein regulatory complex subunit 2 chr12 Not Cancer Driver No 1 hippie 57 73 13 13 0
CCDC8 CCDC8 Q9H0W5 Coiled-coil domain-containing protein 8 chr19 Not Cancer Driver No 1 hippie 96 505 91 91 0
CCNF CCNF P41002 Cyclin-F chr16 Not Cancer Driver No 1 hippie, biogrid 106 221 23 23 3
CCT3 CCT3 P49368 T-complex protein 1 subunit gamma chr1 Not Cancer Driver No 1 intact 71 95 12 12 0
CCT7 CCT7 Q99832 T-complex protein 1 subunit eta chr2 Not Cancer Driver No 1 hippie 59 36 6 6 0
CCT8 CCT8 P50990 T-complex protein 1 subunit theta chr21 Not Cancer Driver No 1 intact 41 36 2 2 0
CD4 CD4 P01730 T-cell surface glycoprotein CD4 chr12 Not Cancer Driver No 1 hippie 69 56 11 11 0
CD44 CD44 P16070 CD44 antigen chr11 Not Cancer Driver No 1 hippie 75 542 60 60 0
CDC27_ENST00000066544 CDC27 P30260 Cell division cycle protein 27 homolog chr17 Not Cancer Driver No 1 hippie 179 289 75 75 0
CDC42SE1_ENST00000540998 CDC42SE1 Q9NRR8 CDC42 small effector protein 1 chr1 Not Cancer Driver No 1 hippie 10 70 10 10 0
CDC73 CDC73 Q6P1J9 Parafibromin chr1 Census, Compendium Yes 1 hippie 110 210 39 39 2
CDH1 CDH1 P12830 Cadherin-1 chr16 Census, Compendium Yes 1 hippie 150 400 82 82 5
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 Not Cancer Driver No 1 hippie 24 0 0 0 0
CEP192 CEP192 Q8TEP8 Centrosomal protein of 192 kDa chr18 Not Cancer Driver No 1 hippie 274 1214 110 110 0
CEP250 CEP250 Q9BV73 Centrosome-associated protein CEP250 chr20 Not Cancer Driver No 1 hippie 250 1859 195 195 0
CFL1_ENST00000308162 CFL1 P23528 Cofilin-1 chr11 Not Cancer Driver No 1 hippie, biogrid 21 4 0 0 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 3 intact, hippie 287 145 18 18 151
CHD3_ENST00000330494 CHD3 Q12873 Chromodomain-helicase-DNA-binding protein 3 chr17 Not Cancer Driver No 1 hippie 235 1015 122 122 18
CHD4 CHD4 Q14839 Chromodomain-helicase-DNA-binding protein 4 chr12 Census, Compendium Yes 1 hippie 419 974 177 177 6
CHEK2_ENST00000405598 CHEK2 O96017 Serine/threonine-protein kinase Chk2 chr22 Census, Compendium Yes 1 intact, hippie 335 157 130 130 13
CHMP4C CHMP4C Q96CF2 Charged multivesicular body protein 4c chr8 Not Cancer Driver No 1 hippie 33 224 31 31 0
CKB CKB P12277 Creatine kinase B-type chr14 Not Cancer Driver No 1 hippie, biogrid 31 102 4 4 0
CLIC1_ENST00000375779 CLIC1 O00299 Chloride intracellular channel protein 1 chr6 Not Cancer Driver No 1 hippie, biogrid 32 27 5 5 0
CLIC4 CLIC4 Q9Y696 Chloride intracellular channel protein 4 chr1 Not Cancer Driver No 1 hippie, biogrid 24 49 4 4 0
CLK1_ENST00000321356 CLK1 P49759 Dual specificity protein kinase CLK1 chr2 Not Cancer Driver No 1 hippie 64 131 21 21 0
CLTCL1 CLTCL1 P53675 Clathrin heavy chain 2 chr22 Census, Compendium Yes 1 hippie 210 10 1 1 0
COL14A1 COL14A1 Q05707 Collagen alpha-1(XIV) chain chr8 Not Cancer Driver No 1 intact, hippie 402 711 188 188 0
COP1 COP1 Q8NHY2 E3 ubiquitin-protein ligase COP1 chr1 Not Cancer Driver No 1 intact 106 147 11 11 0
COPB1_ENST00000439561 COPB1 P53618 Coatomer subunit beta chr11 Not Cancer Driver No 1 hippie 110 95 10 10 1
COPS5 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 Not Cancer Driver No 1 hippie 36 32 7 7 0
CPSF7_ENST00000394888 CPSF7 Q8N684 Cleavage and polyadenylation specificity factor subunit 7 chr11 Not Cancer Driver No 1 hippie 55 398 52 52 0
CPT1A_ENST00000539743 CPT1A P50416 Carnitine O-palmitoyltransferase 1, liver isoform chr11 Not Cancer Driver No 1 hippie 144 62 10 10 15
CRLF1 CRLF1 O75462 Cytokine receptor-like factor 1 chr19 Not Cancer Driver No 1 hippie 51 101 7 7 14
CTBP1 CTBP1 Q13363 C-terminal-binding protein 1 chr4 Not Cancer Driver No 1 intact, hippie 42 123 9 9 1
CUL1_ENST00000602748 CUL1 Q13616 Cullin-1 chr7 Not Cancer Driver No 1 intact, hippie 151 65 9 9 0
CUL2_ENST00000374748 CUL2 Q13617 Cullin-2 chr10 Not Cancer Driver No 1 intact, hippie 87 66 3 3 0
CUL3 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 intact, hippie 123 167 23 23 3
CUL4A CUL4A Q13619 Cullin-4A chr13 Not Cancer Driver No 1 intact, hippie 64 102 2 2 0
CUL4B CUL4B Q13620 Cullin-4B chrX Not Cancer Driver No 1 intact, hippie 138 207 38 38 2
CUL5 CUL5 Q93034 Cullin-5 chr11 Not Cancer Driver No 1 intact, hippie 97 5 1 1 0
CUL7_ENST00000265348 CUL7 Q14999 Cullin-7 chr6 Not Cancer Driver No 1 hippie 188 372 41 41 3
CXCL2 CXCL2 P19875 C-X-C motif chemokine 2 chr4 Not Cancer Driver No 1 hippie 11 15 5 5 0
CYB5B CYB5B O43169 Cytochrome b5 type B chr16 Not Cancer Driver No 1 hippie 17 58 2 2 0
CYB5R3_ENST00000352397 CYB5R3 P00387 NADH-cytochrome b5 reductase 3 chr22 Not Cancer Driver No 1 hippie 42 24 3 3 9
CYLD CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 Census, Compendium Yes 1 hippie 116 213 31 31 3
CYSLTR2_ENST00000614739 CYSLTR2 Q9NS75 Cysteinyl leukotriene receptor 2 chr13 Census, Compendium Yes 1 intact, hippie 64 0 0 0 0
DCLK2_ENST00000296550 DCLK2 Q8N568 Serine/threonine-protein kinase DCLK2 chr4 Not Cancer Driver No 1 hippie 105 260 23 23 0
DCPS DCPS Q96C86 m7GpppX diphosphatase chr11 Not Cancer Driver No 1 hippie 48 53 6 6 1
DDAH2_ENST00000375787 DDAH2 O95865 N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 chr6 Not Cancer Driver No 1 hippie, biogrid 24 96 6 6 0
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 Not Cancer Driver No 1 hippie 34 181 23 23 0
DDX39B_ENST00000458640 DDX39B Q13838 Spliceosome RNA helicase DDX39B chr6 Not Cancer Driver No 1 hippie 49 34 8 8 0
DDX3X_ENST00000629496 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX Census, Compendium Yes 1 hippie 133 301 47 47 18
DEDD_ENST00000545495 DEDD O75618 Death effector domain-containing protein chr1 Not Cancer Driver No 1 hippie 36 90 7 7 0
DES DES P17661 Desmin chr2 Not Cancer Driver No 1 intact, hippie 71 264 41 41 35
DHFR2_ENST00000314636 DHFR2 Q86XF0 Dihydrofolate reductase 2, mitochondrial chr3 Not Cancer Driver No 1 hippie 25 20 0 0 0
DHX15 DHX15 O43143 ATP-dependent RNA helicase DHX15 chr4 Not Cancer Driver No 1 hippie 110 180 30 30 0
DHX30 DHX30 Q7L2E3 ATP-dependent RNA helicase DHX30 chr3 Not Cancer Driver No 1 hippie 165 260 40 40 6
DHX8 DHX8 Q14562 ATP-dependent RNA helicase DHX8 chr17 Not Cancer Driver No 1 hippie 138 490 72 72 0
DIAPH3 DIAPH3 Q9NSV4 Protein diaphanous homolog 3 chr13 Not Cancer Driver No 1 hippie 189 492 78 78 0
DPH5 DPH5 Q9H2P9 Diphthine methyl ester synthase chr1 Not Cancer Driver No 1 hippie 25 18 1 1 0
DUT DUT P33316 Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial chr15 Not Cancer Driver No 1 hippie, biogrid 19 128 8 8 0
DYRK2 DYRK2 Q92630 Dual specificity tyrosine-phosphorylation-regulated kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 77 294 39 39 0
E2F4 E2F4 Q16254 Transcription factor E2F4 chr16 Not Cancer Driver No 1 hippie 44 242 32 32 0
EBP EBP Q15125 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase chrX Not Cancer Driver No 1 hippie 30 9 0 0 9
EED_ENST00000263360 EED O75530 Polycomb protein EED chr11 Census Yes 1 hippie 64 79 11 11 6
EEF1B2_ENST00000236957 EEF1B2 P24534 Elongation factor 1-beta chr2 Not Cancer Driver No 1 hippie 63 71 11 11 0
EEF2 EEF2 P13639 Elongation factor 2 chr19 Not Cancer Driver No 1 hippie, biogrid 111 78 14 14 1
EFEMP1_ENST00000355426 EFEMP1 Q12805 EGF-containing fibulin-like extracellular matrix protein 1 chr2 Not Cancer Driver No 1 hippie 95 73 21 21 1
EFTUD2 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 132 179 30 30 3
EMC1 EMC1 Q8N766 ER membrane protein complex subunit 1 chr1 Not Cancer Driver No 1 intact, hippie 107 59 6 6 2
EMC2 EMC2 Q15006 ER membrane protein complex subunit 2 chr8 Not Cancer Driver No 1 hippie 48 29 3 3 0
EMC4 EMC4 Q5J8M3 ER membrane protein complex subunit 4 chr15 Not Cancer Driver No 1 hippie 15 17 2 2 0
ENDOD1 ENDOD1 O94919 Endonuclease domain-containing 1 protein chr11 Not Cancer Driver No 1 hippie 51 72 9 9 0
ENO2 ENO2 P09104 Gamma-enolase chr12 Not Cancer Driver No 3 hippie, biogrid 48 12 2 2 0
ENO3 ENO3 P13929 Beta-enolase chr17 Not Cancer Driver No 3 intact, hippie, biogrid 46 26 1 1 2
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 334 1790 196 196 1
ERAP1_ENST00000443439 ERAP1 Q9NZ08 Endoplasmic reticulum aminopeptidase 1 chr5 Not Cancer Driver No 1 hippie 78 70 2 2 0
ERG28 ERG28 Q9UKR5 Ergosterol biosynthetic protein 28 homolog chr14 Not Cancer Driver No 1 hippie 19 3 0 0 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
EZR EZR P15311 Ezrin chr6 Census Yes 1 hippie, biogrid 66 295 35 35 0
FABP5 FABP5 Q01469 Fatty acid-binding protein 5 chr8 Not Cancer Driver No 1 hippie, biogrid 15 4 4 4 0
FAF1 FAF1 Q9UNN5 FAS-associated factor 1 chr1 Not Cancer Driver No 1 hippie 83 241 34 34 0
FAF2 FAF2 Q96CS3 FAS-associated factor 2 chr5 Not Cancer Driver No 1 hippie 54 171 16 16 0
FAM136A FAM136A Q96C01 Protein FAM136A chr2 Not Cancer Driver No 1 hippie, biogrid 17 13 1 1 0
FANCA FANCA O15360 Fanconi anemia group A protein chr16 Census, Compendium Yes 1 hippie 160 154 15 15 27
FANCD2_ENST00000383807 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 Census, Compendium Yes 1 hippie 176 181 14 14 3
FARS2_ENST00000274680 FARS2 O95363 Phenylalanine--tRNA ligase, mitochondrial chr6 Not Cancer Driver No 1 hippie 66 73 17 17 4
FAT4 FAT4 Q6V0I7 Protocadherin Fat 4 chr4 Census, Compendium Yes 1 hippie 1315 1400 367 367 7
FBL FBL P22087 rRNA 2'-O-methyltransferase fibrillarin chr19 Not Cancer Driver No 1 hippie 46 145 22 22 0
FBP1_ENST00000375326 FBP1 P09467 Fructose-1,6-bisphosphatase 1 chr9 Not Cancer Driver No 1 hippie 33 19 0 0 4
FBXO25 FBXO25 Q8TCJ0 F-box only protein 25 chr8 Not Cancer Driver No 1 hippie 33 20 0 0 0
FBXO5 FBXO5 Q9UKT4 F-box only protein 5 chr6 Not Cancer Driver No 1 hippie 48 113 13 13 0
FBXO6 FBXO6 Q9NRD1 F-box only protein 6 chr1 Not Cancer Driver No 1 hippie 31 27 3 3 0
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 Census, Compendium Yes 1 hippie 322 230 38 38 0
FEN1 FEN1 P39748 Flap endonuclease 1 chr11 Census Yes 1 hippie, biogrid 35 111 11 11 0
FGD5 FGD5 Q6ZNL6 FYVE, RhoGEF and PH domain-containing protein 5 chr3 Compendium Yes 1 hippie, biogrid 275 915 180 180 0
FH FH P07954 Fumarate hydratase, mitochondrial chr1 Census, Compendium Yes 1 hippie, biogrid 67 76 5 5 13
FHL1_ENST00000345434 FHL1 Q13642 Four and a half LIM domains protein 1 chrX Not Cancer Driver No 1 intact, hippie 56 51 7 7 13
FKBP1A FKBP1A P62942 Peptidyl-prolyl cis-trans isomerase FKBP1A chr20 Not Cancer Driver No 1 hippie, biogrid 15 39 7 7 0
FKBP1B FKBP1B P68106 Peptidyl-prolyl cis-trans isomerase FKBP1B chr2 Not Cancer Driver No 1 hippie, biogrid 10 58 4 4 0
FKBP2_ENST00000449942 FKBP2 P26885 Peptidyl-prolyl cis-trans isomerase FKBP2 chr11 Not Cancer Driver No 1 hippie, biogrid 15 20 1 1 0
FKBP7 FKBP7 Q9Y680 Peptidyl-prolyl cis-trans isomerase FKBP7 chr2 Not Cancer Driver No 1 hippie, biogrid 28 52 9 9 0
FLNC FLNC Q14315 Filamin-C chr7 Not Cancer Driver No 2 hippie, biogrid 546 1442 288 288 7
FN1 FN1 P02751 Fibronectin chr2 Compendium Yes 1 intact, hippie 394 1243 185 185 8
FUS FUS P35637 RNA-binding protein FUS chr16 Census Yes 1 hippie 51 524 51 51 20
FXR1 FXR1 P51114 Fragile X mental retardation syndrome-related protein 1 chr3 Not Cancer Driver No 1 intact, hippie 88 312 53 53 0
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 Not Cancer Driver No 1 hippie 92 70 13 13 0
GABARAP GABARAP O95166 Gamma-aminobutyric acid receptor-associated protein chr17 Not Cancer Driver No 1 hippie 9 11 0 0 0
GABARAPL1_ENST00000545887 GABARAPL1 Q9H0R8 Gamma-aminobutyric acid receptor-associated protein-like 1 chr12 Not Cancer Driver No 1 hippie 19 10 1 1 0
GABARAPL2 GABARAPL2 P60520 Gamma-aminobutyric acid receptor-associated protein-like 2 chr16 Not Cancer Driver No 1 hippie 11 2 1 1 0
GAPDH GAPDH P04406 Glyceraldehyde-3-phosphate dehydrogenase chr12 Not Cancer Driver No 2 hippie, biogrid 39 24 3 3 0
GATAD1 GATAD1 Q8WUU5 GATA zinc finger domain-containing protein 1 chr7 Not Cancer Driver No 1 hippie 14 131 4 4 1
GCSH GCSH P23434 Glycine cleavage system H protein, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 15 25 0 0 0
GIPC3 GIPC3 Q8TF64 PDZ domain-containing protein GIPC3 chr19 Not Cancer Driver No 1 hippie 38 118 13 13 7
GJA1 GJA1 P17302 Gap junction alpha-1 protein chr6 Not Cancer Driver No 1 hippie 86 110 26 26 50
GLIS3_ENST00000324333 GLIS3 Q8NEA6 Zinc finger protein GLIS3 chr9 Not Cancer Driver No 1 hippie 158 541 109 109 0
GLRX5 GLRX5 Q86SX6 Glutaredoxin-related protein 5, mitochondrial chr14 Not Cancer Driver No 1 hippie, biogrid 7 23 0 0 2
GOT2 GOT2 P00505 Aspartate aminotransferase, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 61 25 3 3 1
GPI_ENST00000644934 GPI P06744 Glucose-6-phosphate isomerase chr19 Not Cancer Driver No 1 hippie, biogrid 77 73 11 11 24
GPX4_ENST00000616066 GPX4 P36969 Phospholipid hydroperoxide glutathione peroxidase chr19 Not Cancer Driver No 1 hippie, biogrid 14 0 0 0 0
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 intact, hippie 28 10 1 1 0
GRHPR GRHPR Q9UBQ7 Glyoxylate reductase/hydroxypyruvate reductase chr9 Not Cancer Driver No 1 hippie, biogrid 31 36 4 4 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 Not Cancer Driver No 1 hippie 56 146 13 13 0
GSTM3_ENST00000361066 GSTM3 P21266 Glutathione S-transferase Mu 3 chr1 Not Cancer Driver No 1 hippie 32 0 0 0 0
GSTP1_ENST00000642444 GSTP1 P09211 Glutathione S-transferase P chr11 Not Cancer Driver No 1 hippie, biogrid 32 0 0 0 0
H2AFX H2AX P16104 Histone H2AX chr11 Not Cancer Driver No 1 intact 20 68 10 10 0
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 Not Cancer Driver No 1 hippie 47 135 10 10 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 Not Cancer Driver No 1 hippie 46 145 14 14 0
HDAC4 HDAC4 P56524 Histone deacetylase 4 chr2 Not Cancer Driver No 1 hippie 182 749 132 132 0
HDAC6_ENST00000426196 HDAC6 Q9UBN7 Histone deacetylase 6 chrX Not Cancer Driver No 1 hippie 178 409 59 59 0
HDGF_ENST00000357325 HDGF P51858 Hepatoma-derived growth factor chr1 Not Cancer Driver No 1 hippie 35 203 29 29 0
HEMGN_ENST00000259456 HEMGN Q9BXL5 Hemogen chr9 Not Cancer Driver No 1 hippie 78 473 73 73 0
HEXIM1 HEXIM1 O94992 Protein HEXIM1 chr17 Not Cancer Driver No 1 hippie 40 352 40 40 0
HEY2 HEY2 Q9UBP5 Hairy/enhancer-of-split related with YRPW motif protein 2 chr6 Not Cancer Driver No 1 hippie 64 179 26 26 0
HINT1 HINT1 P49773 Adenosine 5'-monophosphoramidase HINT1 chr5 Not Cancer Driver No 2 hippie, biogrid 11 6 0 0 6
HINT2 HINT2 Q9BX68 Adenosine 5'-monophosphoramidase HINT2 chr9 Not Cancer Driver No 1 hippie, biogrid 10 29 2 2 0
HIST2H2AB H2AC21 Q8IUE6 Histone H2A type 2-B chr1 Not Cancer Driver No 1 intact 33 61 17 17 0
HK2 HK2 P52789 Hexokinase-2 chr2 Not Cancer Driver No 1 hippie 138 77 7 7 0
HNRNPA1 HNRNPA1 P09651 Heterogeneous nuclear ribonucleoprotein A1 chr12 Not Cancer Driver No 1 hippie 70 290 58 58 4
HNRNPD HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 Not Cancer Driver No 1 hippie 39 206 19 19 0
HNRNPH3 HNRNPH3 P31942 Heterogeneous nuclear ribonucleoprotein H3 chr10 Not Cancer Driver No 1 hippie 42 188 18 18 0
HNRNPK_ENST00000351839 HNRNPK P61978 Heterogeneous nuclear ribonucleoprotein K chr9 Not Cancer Driver No 1 hippie, biogrid 75 302 59 59 0
HNRNPM HNRNPM P52272 Heterogeneous nuclear ribonucleoprotein M chr19 Not Cancer Driver No 1 hippie 108 463 67 67 0
HSD17B10 HSD17B10 Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 chrX Not Cancer Driver No 1 hippie, biogrid 27 15 3 3 11
HSDL2 HSDL2 Q6YN16 Hydroxysteroid dehydrogenase-like protein 2 chr9 Not Cancer Driver No 1 intact, hippie 37 41 5 5 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 1 hippie, biogrid 106 257 37 37 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 1 intact, hippie 100 254 43 43 0
HSP90B1 HSP90B1 P14625 Endoplasmin chr12 Not Cancer Driver No 1 hippie, biogrid 94 268 35 35 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 intact, hippie 149 251 52 52 0
HSPA9 HSPA9 P38646 Stress-70 protein, mitochondrial chr5 Not Cancer Driver No 1 hippie 67 283 26 26 2
HSPB2 HSPB2 Q16082 Heat shock protein beta-2 chr11 Not Cancer Driver No 1 intact, hippie 25 103 11 11 0
HSPE1 HSPE1 P61604 10 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 8 3 0 0 0
HTRA3 HTRA3 P83110 Serine protease HTRA3 chr4 Not Cancer Driver No 1 intact, hippie 64 57 11 11 0
HTT HTT P42858 Huntingtin chr4 Not Cancer Driver No 2 intact, hippie 336 666 69 69 2
HUWE1_ENST00000262854 HUWE1 Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 chrX Not Cancer Driver No 1 hippie 669 2091 329 329 21
IDH2 IDH2 P48735 Isocitrate dehydrogenase [NADP], mitochondrial chr15 Census, Compendium Yes 1 hippie, biogrid 74 59 1 1 7
IFI16_ENST00000295809 IFI16 Q16666 Gamma-interferon-inducible protein 16 chr1 Not Cancer Driver No 1 hippie 155 419 90 90 0
IFRD2 IFRD2 Q12894 Interferon-related developmental regulator 2 chr3 Not Cancer Driver No 1 hippie 52 156 9 9 0
IFT88_ENST00000351808 IFT88 Q13099 Intraflagellar transport protein 88 homolog chr13 Not Cancer Driver No 1 intact, hippie 99 280 30 30 0
INSIG2 INSIG2 Q9Y5U4 Insulin-induced gene 2 protein chr2 Not Cancer Driver No 1 hippie 47 11 3 3 0
IPO4 IPO4 Q8TEX9 Importin-4 chr14 Not Cancer Driver No 1 hippie 106 87 5 5 0
IRF2 IRF2 P14316 Interferon regulatory factor 2 chr4 Not Cancer Driver No 1 intact, hippie 85 288 73 73 0
ISG15 ISG15 P05161 Ubiquitin-like protein ISG15 chr1 Not Cancer Driver No 1 hippie 12 24 2 2 0
ISOC2_ENST00000425675 ISOC2 Q96AB3 Isochorismatase domain-containing protein 2 chr19 Not Cancer Driver No 1 hippie 24 8 0 0 0
ITGA4 ITGA4 P13612 Integrin alpha-4 chr2 Not Cancer Driver No 1 hippie 254 97 27 27 0
ITGB1_ENST00000302278 ITGB1 P05556 Integrin beta-1 chr10 Not Cancer Driver No 1 hippie 103 84 10 10 0
ITPA ITPA Q9BY32 Inosine triphosphate pyrophosphatase chr20 Not Cancer Driver No 1 hippie, biogrid 21 10 1 1 1
IVNS1ABP IVNS1ABP Q9Y6Y0 Influenza virus NS1A-binding protein chr1 Not Cancer Driver No 1 hippie 85 90 12 12 0
IWS1 IWS1 Q96ST2 Protein IWS1 homolog chr2 Not Cancer Driver No 1 hippie 80 737 72 72 0
JUN JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 35 281 25 25 0
KANK1_ENST00000382303 KANK1 Q14678 KN motif and ankyrin repeat domain-containing protein 1 chr9 Not Cancer Driver No 1 hippie 183 804 100 100 0
KCNMA1 KCNMA1 Q12791 Calcium-activated potassium channel subunit alpha-1 chr10 Not Cancer Driver No 1 intact 222 225 39 39 5
KDM2A KDM2A Q9Y2K7 Lysine-specific demethylase 2A chr11 Not Cancer Driver No 1 hippie 131 387 48 48 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
KIF1B_ENST00000377086 KIF1B O60333 Kinesin-like protein KIF1B chr1 Not Cancer Driver No 1 hippie 253 633 106 106 1
KIF23 KIF23 Q02241 Kinesin-like protein KIF23 chr15 Not Cancer Driver No 1 hippie 102 559 62 62 0
KLHDC3 KLHDC3 Q9BQ90 Kelch domain-containing protein 3 chr6 Not Cancer Driver No 1 hippie 43 12 1 1 0
KNSTRN KNSTRN Q9Y448 Small kinetochore-associated protein chr15 Census Yes 1 hippie 75 246 67 67 0
KRAS KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 1 hippie 788 7 2 2 27
KRT17 KRT17 Q04695 Keratin, type I cytoskeletal 17 chr17 Not Cancer Driver No 1 hippie 86 160 31 31 18
L1TD1 L1TD1 Q5T7N2 LINE-1 type transposase domain-containing protein 1 chr1 Not Cancer Driver No 1 intact, hippie 149 534 114 114 0
LACTB2 LACTB2 Q53H82 Endoribonuclease LACTB2 chr8 Not Cancer Driver No 1 hippie, biogrid 34 21 1 1 0
LARP7_ENST00000344442 LARP7 Q4G0J3 La-related protein 7 chr4 Not Cancer Driver No 1 hippie 58 350 44 44 0
LDHA_ENST00000422447 LDHA P00338 L-lactate dehydrogenase A chain chr11 Not Cancer Driver No 1 hippie, biogrid 40 9 0 0 0
LDHB_ENST00000350669 LDHB P07195 L-lactate dehydrogenase B chain chr12 Not Cancer Driver No 1 hippie, biogrid 47 15 2 2 11
LETMD1_ENST00000262055 LETMD1 Q6P1Q0 LETM1 domain-containing protein 1 chr12 Not Cancer Driver No 1 hippie 49 0 0 0 0
LGALS3 LGALS3 P17931 Galectin-3 chr14 Not Cancer Driver No 1 hippie, biogrid 15 133 6 6 0
LIG4 LIG4 P49917 DNA ligase 4 chr13 Not Cancer Driver No 1 hippie 134 63 10 10 2
LMNA LMNA P02545 Prelamin-A/C chr1 Census Yes 1 hippie 68 544 49 49 131
LONRF3 LONRF3 Q496Y0 LON peptidase N-terminal domain and RING finger protein 3 chrX Not Cancer Driver No 1 hippie 105 262 36 36 0
LRRC42_ENST00000319223 LRRC42 Q9Y546 Leucine-rich repeat-containing protein 42 chr1 Not Cancer Driver No 1 hippie 54 90 5 5 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 519 90 17 17 23
LUC7L3_ENST00000240304 LUC7L3 O95232 Luc7-like protein 3 chr17 Not Cancer Driver No 1 hippie 59 323 47 47 0
M6PR M6PR P20645 Cation-dependent mannose-6-phosphate receptor chr12 Not Cancer Driver No 1 hippie 16 35 4 4 0
MAGEL2 MAGEL2 Q9UJ55 MAGE-like protein 2 chr15 Not Cancer Driver No 1 hippie 178 1010 118 118 0
MAP1LC3B MAP1LC3B Q9GZQ8 Microtubule-associated proteins 1A/1B light chain 3B chr16 Not Cancer Driver No 1 intact, hippie 10 17 1 1 0
MAP2K5 MAP2K5 Q13163 Dual specificity mitogen-activated protein kinase kinase 5 chr15 Not Cancer Driver No 1 hippie 40 85 10 10 0
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 Not Cancer Driver No 1 intact, hippie 104 333 66 66 6
MAPK13 MAPK13 O15264 Mitogen-activated protein kinase 13 chr6 Not Cancer Driver No 1 intact, hippie 51 50 15 15 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 Not Cancer Driver No 1 hippie 128 750 126 126 18
MBNL2 MBNL2 Q5VZF2 Muscleblind-like protein 2 chr13 Not Cancer Driver No 1 hippie 56 110 17 17 0
MCM2 MCM2 P49736 DNA replication licensing factor MCM2 chr3 Not Cancer Driver No 1 hippie 104 275 38 38 1
MCM5 MCM5 P33992 DNA replication licensing factor MCM5 chr22 Not Cancer Driver No 1 hippie 88 109 20 20 1
MCPH1 MCPH1 Q8NEM0 Microcephalin chr8 Not Cancer Driver No 1 hippie 110 446 62 62 1
MDC1 MDC1 Q14676 Mediator of DNA damage checkpoint protein 1 chr6 Not Cancer Driver No 1 hippie 249 1829 223 223 0
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 Census, Compendium Yes 1 hippie 56 297 37 37 0
MED13 MED13 Q9UHV7 Mediator of RNA polymerase II transcription subunit 13 chr17 Not Cancer Driver No 1 hippie 288 905 127 127 3
MED29_ENST00000599213 MED29 Q9NX70 Mediator of RNA polymerase II transcription subunit 29 chr19 Not Cancer Driver No 1 hippie 21 119 10 10 0
MEPCE MEPCE Q7L2J0 7SK snRNA methylphosphate capping enzyme chr7 Not Cancer Driver No 1 hippie 76 446 42 42 0
METTL14 METTL14 Q9HCE5 N6-adenosine-methyltransferase non-catalytic subunit chr4 Not Cancer Driver No 1 hippie 60 224 26 26 0
MIF MIF P14174 Macrophage migration inhibitory factor chr22 Not Cancer Driver No 1 hippie, biogrid 4 0 0 0 0
MMGT1 MMGT1 Q8N4V1 ER membrane protein complex subunit 5 chrX Not Cancer Driver No 1 hippie 24 17 4 4 0
MORC4 MORC4 Q8TE76 MORC family CW-type zinc finger protein 4 chrX Not Cancer Driver No 1 hippie 139 377 48 48 0
MPDZ MPDZ O75970 Multiple PDZ domain protein chr9 Not Cancer Driver No 1 hippie 287 858 122 122 0
MPHOSPH8 MPHOSPH8 Q99549 M-phase phosphoprotein 8 chr13 Not Cancer Driver No 1 hippie 105 523 66 66 0
MPST_ENST00000341116 MPST P25325 3-mercaptopyruvate sulfurtransferase chr22 Not Cancer Driver No 1 hippie, biogrid 20 72 8 8 0
MRPL37_ENST00000360840 MRPL37 Q9BZE1 39S ribosomal protein L37, mitochondrial chr1 Not Cancer Driver No 1 hippie 44 36 5 5 0
MSN MSN P26038 Moesin chrX Census, Compendium Yes 1 hippie, biogrid 108 286 56 56 1
MTDH MTDH Q86UE4 Protein LYRIC chr8 Not Cancer Driver No 1 hippie 83 516 81 81 0
MTFR1 MTFR1 Q15390 Mitochondrial fission regulator 1 chr8 Not Cancer Driver No 1 hippie 41 230 27 27 0
MVK MVK Q03426 Mevalonate kinase chr12 Not Cancer Driver No 1 hippie 50 25 0 0 38
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
MYO18A MYO18A Q92614 Unconventional myosin-XVIIIa chr17 Not Cancer Driver No 1 hippie 268 1237 176 176 0
MYO1E MYO1E Q12965 Unconventional myosin-Ie chr15 Not Cancer Driver No 1 hippie 137 229 14 14 1
MYO6 MYO6 Q9UM54 Unconventional myosin-VI chr6 Not Cancer Driver No 1 hippie 176 342 41 41 3
MYOC MYOC Q99972 Myocilin chr1 Not Cancer Driver No 1 hippie 92 196 43 43 58
NAA40 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 22 30 3 3 0
NAB1 NAB1 Q13506 NGFI-A-binding protein 1 chr2 Not Cancer Driver No 1 hippie 54 250 30 30 0
NAP1L4 NAP1L4 Q99733 Nucleosome assembly protein 1-like 4 chr11 Not Cancer Driver No 1 hippie 38 194 19 19 0
NAT1_ENST00000517492 NAT1 P18440 Arylamine N-acetyltransferase 1 chr8 Not Cancer Driver No 1 intact 35 0 0 0 0
NAXD NAXD Q8IW45-2 Isoform 2 of ATP-dependent (S)-NAD(P)H-hydrate dehydratase chr13 Not Cancer Driver No 1 hippie 48 111 11 11 0
NCAPD3 NCAPD3 P42695 Condensin-2 complex subunit D3 chr11 Not Cancer Driver No 1 hippie 193 304 42 42 1
NCOR1 NCOR1 O75376 Nuclear receptor corepressor 1 chr17 Census, Compendium Yes 1 intact, hippie 352 2347 340 340 0
NDN NDN Q99608 Necdin chr15 Not Cancer Driver No 1 intact, hippie 123 117 42 42 0
NDUFAB1_ENST00000007516 NDUFAB1 O14561 Acyl carrier protein, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 23 0 0 0 0
NEDD4 NEDD4 P46934 E3 ubiquitin-protein ligase NEDD4 chr15 Not Cancer Driver No 1 hippie, biogrid 150 711 79 79 0
NEK4 NEK4 P51957 Serine/threonine-protein kinase Nek4 chr3 Not Cancer Driver No 1 hippie 78 492 49 49 0
NENF NENF Q9UMX5 Neudesin chr1 Not Cancer Driver No 1 hippie, biogrid 15 98 7 7 0
NFATC3 NFATC3 Q12968 Nuclear factor of activated T-cells, cytoplasmic 3 chr16 Not Cancer Driver No 1 hippie 112 730 80 80 0
NFKB1_ENST00000505458 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 Not Cancer Driver No 1 intact, hippie 104 344 38 38 0
NIPSNAP1 NIPSNAP1 Q9BPW8 Protein NipSnap homolog 1 chr22 Not Cancer Driver No 1 hippie 31 9 0 0 0
NIT2 NIT2 Q9NQR4 Omega-amidase NIT2 chr3 Not Cancer Driver No 1 hippie, biogrid 47 0 0 0 0
NLRP7_ENST00000590030 NLRP7 Q8WX94 NACHT, LRR and PYD domains-containing protein 7 chr19 Not Cancer Driver No 1 hippie 300 71 20 20 9
NME1-NME2 NME1-NME2 P22392-2 Isoform 3 of Nucleoside diphosphate kinase B chr17 Not Cancer Driver No 1 biogrid 21 20 1 1 0
NME2 NME2 P22392 Nucleoside diphosphate kinase B chr17 Not Cancer Driver No 1 hippie, biogrid 13 11 1 1 0
NOP56 NOP56 O00567 Nucleolar protein 56 chr20 Not Cancer Driver No 1 hippie 83 191 34 34 0
NOS2 NOS2 P35228 Nitric oxide synthase, inducible chr17 Not Cancer Driver No 1 hippie, biogrid 207 201 33 33 0
NPLOC4 NPLOC4 Q8TAT6 Nuclear protein localization protein 4 homolog chr17 Not Cancer Driver No 1 hippie 78 47 8 8 0
NPM1 NPM1 P06748 Nucleophosmin chr5 Census, Compendium Yes 1 hippie 29 249 22 22 0
NR2C2_ENST00000393102 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 hippie 62 186 24 24 0
NSD2_ENST00000382892 NSD2 O96028 Histone-lysine N-methyltransferase NSD2 chr4 Census, Compendium Yes 1 hippie 191 552 76 76 0
NSL1 NSL1 Q96IY1 Kinetochore-associated protein NSL1 homolog chr1 Not Cancer Driver No 1 intact 30 117 12 12 0
NTN4 NTN4 Q9HB63 Netrin-4 chr12 Not Cancer Driver No 1 hippie 114 8 1 1 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
NUDC NUDC Q9Y266 Nuclear migration protein nudC chr1 Not Cancer Driver No 1 hippie 36 235 29 29 0
NUMA1 NUMA1 Q14980 Nuclear mitotic apparatus protein 1 chr11 Census, Compendium Yes 1 hippie 234 1864 203 203 0
NUP205 NUP205 Q92621 Nuclear pore complex protein Nup205 chr7 Not Cancer Driver No 1 hippie 251 101 16 16 1
OBSL1 OBSL1 O75147 Obscurin-like protein 1 chr2 Not Cancer Driver No 1 hippie 233 553 60 60 0
OGDH OGDH Q02218 2-oxoglutarate dehydrogenase complex component E1 chr7 Not Cancer Driver No 1 hippie 150 106 19 19 0
OGT OGT O15294 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit chrX Not Cancer Driver No 1 hippie 156 89 16 16 2
OSBPL3 OSBPL3 Q9H4L5 Oxysterol-binding protein-related protein 3 chr7 Not Cancer Driver No 1 hippie 114 324 44 44 0
OTUB1_ENST00000428192 OTUB1 Q96FW1 Ubiquitin thioesterase OTUB1 chr11 Not Cancer Driver No 1 intact, hippie 31 33 2 2 0
P4HB P4HB P07237 Protein disulfide-isomerase chr17 Not Cancer Driver No 2 intact, hippie, biogrid 61 79 15 15 1
PAF1 PAF1 Q8N7H5 RNA polymerase II-associated factor 1 homolog chr19 Not Cancer Driver No 1 intact, hippie 77 378 56 56 0
PAGE4_ENST00000376141 PAGE4 O60829 P antigen family member 4 chrX Not Cancer Driver No 1 hippie 20 102 20 20 0
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 Not Cancer Driver No 2 hippie, biogrid 11 30 0 0 5
PCLAF PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 20 111 20 20 0
PCMT1_ENST00000464889 PCMT1 A0A0A0MRJ6 Protein-L-isoaspartate O-methyltransferase chr6 Not Cancer Driver No 1 hippie, biogrid 34 38 4 4 0
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 Not Cancer Driver No 1 intact, hippie 30 22 3 3 1
PDCD6IP_ENST00000307296 PDCD6IP Q8WUM4 Programmed cell death 6-interacting protein chr3 Not Cancer Driver No 1 hippie, biogrid 85 272 22 22 0
PDE4B PDE4B Q07343 cAMP-specific 3',5'-cyclic phosphodiesterase 4B chr1 Not Cancer Driver No 1 hippie 119 363 42 42 0
PDE4DIP_ENST00000369354 PDE4DIP Q5VU43 Myomegalin chr1 Census, Compendium Yes 1 hippie 555 1633 395 395 0
PDIA3 PDIA3 P30101 Protein disulfide-isomerase A3 chr15 Not Cancer Driver No 1 hippie, biogrid 57 98 11 11 0
PDP1_ENST00000297598 PDP1 Q9P0J1 [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial chr8 Not Cancer Driver No 1 hippie, biogrid 64 96 9 9 0
PDPR PDPR Q8NCN5 Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial chr16 Compendium Yes 1 hippie 142 35 4 4 0
PEF1 PEF1 Q9UBV8 Peflin chr1 Not Cancer Driver No 1 hippie, biogrid 44 122 20 20 0
PER2 PER2 O15055 Period circadian protein homolog 2 chr2 Not Cancer Driver No 1 hippie 166 782 101 101 1
PFN1 PFN1 P07737 Profilin-1 chr17 Not Cancer Driver No 1 hippie, biogrid 16 7 1 1 3
PGAM1 PGAM1 P18669 Phosphoglycerate mutase 1 chr10 Not Cancer Driver No 1 hippie, biogrid 20 70 5 5 0
PGK1 PGK1 P00558 Phosphoglycerate kinase 1 chrX Not Cancer Driver No 2 hippie, biogrid 61 40 5 5 9
PGK2 PGK2 P07205 Phosphoglycerate kinase 2 chr6 Not Cancer Driver No 1 hippie, biogrid 145 37 13 13 0
PGM1_ENST00000371084 PGM1 P36871 Phosphoglucomutase-1 chr1 Not Cancer Driver No 1 hippie, biogrid 62 31 3 3 13
PGR PGR P06401 Progesterone receptor chr11 Not Cancer Driver No 1 intact, hippie 161 480 55 55 0
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 30 157 13 13 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 Not Cancer Driver No 1 hippie 57 99 13 13 23
PITPNB_ENST00000335272 PITPNB P48739 Phosphatidylinositol transfer protein beta isoform chr22 Not Cancer Driver No 1 hippie 26 69 2 2 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PLG PLG P00747 Plasminogen chr6 Not Cancer Driver No 1 hippie 242 230 64 64 9
PMP2 PMP2 P02689 Myelin P2 protein chr8 Not Cancer Driver No 1 hippie, biogrid 27 10 0 0 3
PMPCB PMPCB O75439 Mitochondrial-processing peptidase subunit beta chr7 Not Cancer Driver No 1 hippie 55 22 3 3 5
PNP PNP P00491 Purine nucleoside phosphorylase chr14 Not Cancer Driver No 1 hippie 38 29 2 2 5
POFUT1 POFUT1 Q9H488 GDP-fucose protein O-fucosyltransferase 1 chr20 Not Cancer Driver No 1 hippie 56 17 2 2 0
POGZ POGZ Q7Z3K3 Pogo transposable element with ZNF domain chr1 Not Cancer Driver No 1 hippie 157 746 78 78 0
POLA1_ENST00000379059 POLA1 P09884 DNA polymerase alpha catalytic subunit chrX Not Cancer Driver No 1 hippie 185 347 45 45 3
POLE3 POLE3 Q9NRF9 DNA polymerase epsilon subunit 3 chr9 Not Cancer Driver No 1 hippie 11 117 9 9 0
POLR1A POLR1A O95602 DNA-directed RNA polymerase I subunit RPA1 chr2 Not Cancer Driver No 1 hippie 208 361 64 64 2
PPA2 PPA2 Q9H2U2 Inorganic pyrophosphatase 2, mitochondrial chr4 Not Cancer Driver No 1 hippie, biogrid 49 71 9 9 9
PPFIBP1 PPFIBP1 Q86W92 Liprin-beta-1 chr12 Census Yes 1 hippie 110 555 57 57 0
PPIA PPIA P62937 Peptidyl-prolyl cis-trans isomerase A chr7 Not Cancer Driver No 1 hippie, biogrid 11 24 3 3 0
PPIB PPIB P23284 Peptidyl-prolyl cis-trans isomerase B chr15 Not Cancer Driver No 1 hippie, biogrid 28 16 1 1 1
PPP2R5E PPP2R5E Q16537 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform chr14 Not Cancer Driver No 1 intact, hippie 68 86 20 20 0
PPP5C PPP5C P53041 Serine/threonine-protein phosphatase 5 chr19 Not Cancer Driver No 1 hippie 70 73 12 12 0
PPT1 PPT1 P50897 Palmitoyl-protein thioesterase 1 chr1 Not Cancer Driver No 1 hippie 37 0 0 0 23
PRDX4 PRDX4 Q13162 Peroxiredoxin-4 chrX Not Cancer Driver No 1 hippie 36 29 2 2 0
PRDX5 PRDX5 P30044 Peroxiredoxin-5, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 22 0 0 0 0
PRDX6 PRDX6 P30041 Peroxiredoxin-6 chr1 Not Cancer Driver No 1 hippie, biogrid 46 13 4 4 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 Not Cancer Driver No 1 intact, hippie 110 78 15 15 31
PRPF19 PRPF19 Q9UMS4 Pre-mRNA-processing factor 19 chr11 Not Cancer Driver No 1 hippie 71 109 16 16 0
PRPF8 PRPF8 Q6P2Q9 Pre-mRNA-processing-splicing factor 8 chr17 Not Cancer Driver No 1 hippie 255 225 26 26 8
PRPH PRPH P41219 Peripherin chr12 Not Cancer Driver No 1 hippie, biogrid 37 239 20 20 0
PSMA3 PSMA3 P25788 Proteasome subunit alpha type-3 chr14 Not Cancer Driver No 1 hippie 27 30 5 5 0
PSMD14 PSMD14 O00487 26S proteasome non-ATPase regulatory subunit 14 chr2 Not Cancer Driver No 1 hippie 23 67 6 6 0
PTMA PTMA P06454 Prothymosin alpha chr2 Compendium Yes 1 hippie, biogrid 10 111 10 10 0
PTPN9 PTPN9 P43378 Tyrosine-protein phosphatase non-receptor type 9 chr15 Not Cancer Driver No 1 hippie 77 78 5 5 0
PUS7_ENST00000469408 PUS7 Q96PZ0 Pseudouridylate synthase 7 homolog chr7 Not Cancer Driver No 1 hippie, biogrid 73 162 17 17 1
PXN_ENST00000228307 PXN P49023 Paxillin chr12 Not Cancer Driver No 1 hippie 62 341 24 24 0
QRICH1_ENST00000357496 QRICH1 Q2TAL8 Transcriptional regulator QRICH1 chr3 Not Cancer Driver No 1 hippie 93 423 55 55 0
RAB11FIP5 RAB11FIP5 Q9BXF6 Rab11 family-interacting protein 5 chr2 Not Cancer Driver No 1 hippie, biogrid 83 533 70 70 0
RAB34_ENST00000436730 RAB34 Q9BZG1 Ras-related protein Rab-34 chr17 Not Cancer Driver No 1 hippie 41 1 0 0 0
RAD52 RAD52 P43351 DNA repair protein RAD52 homolog chr12 Not Cancer Driver No 1 intact, hippie 41 251 30 30 0
RANBP9 RANBP9 Q96S59 Ran-binding protein 9 chr6 Not Cancer Driver No 1 hippie 73 413 30 30 0
RAPGEF6_ENST00000509018 RAPGEF6 Q8TEU7 Rap guanine nucleotide exchange factor 6 chr5 Not Cancer Driver No 1 hippie 192 789 92 92 0
RBM25 RBM25 P49756 RNA-binding protein 25 chr14 Not Cancer Driver No 1 hippie 124 549 88 88 0
RBM39 RBM39 Q14498 RNA-binding protein 39 chr20 Compendium Yes 1 hippie 81 228 39 39 0
RBMS2 RBMS2 Q15434 RNA-binding motif, single-stranded-interacting protein 2 chr12 Not Cancer Driver No 1 hippie 53 265 38 38 0
RBP1_ENST00000619087 RBP1 P09455 Retinol-binding protein 1 chr3 Not Cancer Driver No 1 intact 24 0 0 0 0
RBX1 RBX1 P62877 E3 ubiquitin-protein ligase RBX1 chr22 Not Cancer Driver No 1 hippie 10 18 1 1 0
RCC1_ENST00000373833 RCC1 P18754 Regulator of chromosome condensation chr1 Not Cancer Driver No 1 hippie 54 143 15 15 0
RCN1 RCN1 Q15293 Reticulocalbin-1 chr11 Not Cancer Driver No 1 hippie, biogrid 35 158 19 19 0
RDX_ENST00000343115 RDX P35241 Radixin chr11 Not Cancer Driver No 1 hippie, biogrid 71 297 37 37 1
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 138 608 71 71 1
RHOF RHOF Q9HBH0 Rho-related GTP-binding protein RhoF chr12 Not Cancer Driver No 1 hippie 18 10 0 0 0
RIOK1 RIOK1 Q9BRS2 Serine/threonine-protein kinase RIO1 chr6 Not Cancer Driver No 1 hippie 69 301 37 37 0
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 Not Cancer Driver No 1 intact, hippie 63 143 20 20 0
RNF10_ENST00000325954 RNF10 Q8N5U6 RING finger protein 10 chr12 Not Cancer Driver No 1 hippie 108 455 63 63 0
RNF4 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 Not Cancer Driver No 1 hippie 14 117 7 7 0
RPTOR RPTOR Q8N122 Regulatory-associated protein of mTOR chr17 Not Cancer Driver No 1 hippie 176 241 21 21 0
RXFP3 RXFP3 Q9NSD7 Relaxin-3 receptor 1 chr5 Not Cancer Driver No 1 intact, hippie 141 37 25 25 0
SCAF8_ENST00000367178 SCAF8 Q9UPN6 SR-related and CTD-associated factor 8 chr6 Not Cancer Driver No 1 hippie 155 939 118 118 0
SCARA3 SCARA3 Q6AZY7 Scavenger receptor class A member 3 chr8 Not Cancer Driver No 1 hippie 80 230 29 29 0
SENP2 SENP2 Q9HC62 Sentrin-specific protease 2 chr3 Not Cancer Driver No 1 hippie 73 285 38 38 0
SERPING1 SERPING1 P05155 Plasma protease C1 inhibitor chr11 Not Cancer Driver No 1 hippie 74 113 13 13 40
SET SET Q01105 Protein SET chr9 Census, Compendium Yes 1 hippie 35 221 26 26 2
SF3A1 SF3A1 Q15459 Splicing factor 3A subunit 1 chr22 Not Cancer Driver No 1 hippie 82 631 67 67 0
SGCG SGCG Q13326 Gamma-sarcoglycan chr13 Not Cancer Driver No 1 intact, hippie 64 60 12 12 4
SH3KBP1 SH3KBP1 Q96B97 SH3 domain-containing kinase-binding protein 1 chrX Not Cancer Driver No 1 hippie 102 530 82 82 0
SLC25A1 SLC25A1 P53007 Tricarboxylate transport protein, mitochondrial chr22 Not Cancer Driver No 1 hippie 22 34 2 2 17
SLC25A39 SLC25A39 Q9BZJ4 Probable mitochondrial glutathione transporter SLC25A39 chr17 Not Cancer Driver No 1 hippie 43 13 1 1 0
SLC9A1 SLC9A1 P19634 Sodium/hydrogen exchanger 1 chr1 Not Cancer Driver No 1 hippie 89 251 29 29 1
SMARCE1 SMARCE1 Q969G3 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 chr17 Census Yes 1 hippie 47 332 36 36 2
SMC3 SMC3 Q9UQE7 Structural maintenance of chromosomes protein 3 chr10 Not Cancer Driver No 1 hippie 149 605 70 70 0
SNAPC3_ENST00000610884 SNAPC3 Q92966 snRNA-activating protein complex subunit 3 chr9 Not Cancer Driver No 1 intact, hippie 30 99 2 2 0
SNRNP25 SNRNP25 Q9BV90 U11/U12 small nuclear ribonucleoprotein 25 kDa protein chr16 Not Cancer Driver No 1 hippie 14 5 1 1 0
SNX1_ENST00000559844 SNX1 Q13596 Sorting nexin-1 chr15 Not Cancer Driver No 1 intact, hippie 61 214 25 25 0
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 Not Cancer Driver No 3 hippie, biogrid 16 93 9 9 79
SPC24 SPC24 Q8NBT2 Kinetochore protein Spc24 chr19 Not Cancer Driver No 1 intact 9 88 5 5 0
SPOP SPOP O43791 Speckle-type POZ protein chr17 Census, Compendium Yes 1 hippie 147 25 5 5 6
SPRTN SPRTN Q9H040 DNA-dependent metalloprotease SPRTN chr1 Not Cancer Driver No 1 hippie 73 252 38 38 1
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 Census Yes 1 hippie 53 130 11 11 1
SRI SRI P30626 Sorcin chr7 Not Cancer Driver No 1 hippie, biogrid 15 32 2 2 0
SRSF7 SRSF7 Q16629 Serine/arginine-rich splicing factor 7 chr2 Not Cancer Driver No 1 hippie 40 175 26 26 0
STAU1 STAU1 O95793 Double-stranded RNA-binding protein Staufen homolog 1 chr20 Not Cancer Driver No 1 hippie 77 456 63 63 0
STK10 STK10 O94804 Serine/threonine-protein kinase 10 chr5 Not Cancer Driver No 1 hippie 120 666 86 86 1
STRIP1 STRIP1 Q5VSL9 Striatin-interacting protein 1 chr1 Not Cancer Driver No 1 hippie 97 267 33 33 0
STUB1 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 Not Cancer Driver No 1 hippie 35 112 14 14 12
STX2 STX2 P32856 Syntaxin-2 chr12 Not Cancer Driver No 1 hippie 43 140 25 25 0
STX6 STX6 O43752 Syntaxin-6 chr1 Not Cancer Driver No 1 hippie 33 78 11 11 0
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 hippie 10 76 7 7 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
SUMO3_ENST00000332859 SUMO3 P55854 Small ubiquitin-related modifier 3 chr21 Not Cancer Driver No 1 hippie 7 87 5 5 0
SUMO4 SUMO4 Q6EEV6 Small ubiquitin-related modifier 4 chr6 Not Cancer Driver No 1 hippie 7 69 4 4 0
SUPT5H SUPT5H O00267 Transcription elongation factor SPT5 chr19 Not Cancer Driver No 1 hippie 165 572 87 87 0
SYT12_ENST00000527043 SYT12 Q8IV01 Synaptotagmin-12 chr11 Not Cancer Driver No 1 hippie 71 73 13 13 0
SZRD1 SZRD1 Q7Z422 SUZ domain-containing protein 1 chr1 Not Cancer Driver No 1 hippie 20 152 20 20 0
TAGLN2_ENST00000368097 TAGLN2 P37802 Transgelin-2 chr1 Not Cancer Driver No 1 hippie, biogrid 28 83 12 12 0
TAGLN3 TAGLN3 Q9UI15 Transgelin-3 chr3 Not Cancer Driver No 1 hippie, biogrid 25 85 18 18 0
TAGLN_ENST00000530649 TAGLN Q01995 Transgelin chr11 Not Cancer Driver No 1 hippie, biogrid 20 94 12 12 0
TALDO1 TALDO1 P37837 Transaldolase chr11 Not Cancer Driver No 1 hippie, biogrid 51 31 4 4 0
TARDBP TARDBP Q13148 TAR DNA-binding protein 43 chr1 Not Cancer Driver No 1 hippie 51 202 15 15 27
TBCA_ENST00000380377 TBCA O75347 Tubulin-specific chaperone A chr5 Not Cancer Driver No 1 hippie, biogrid 8 30 1 1 0
TCAP TCAP O15273 Telethonin chr17 Not Cancer Driver No 1 hippie 16 94 10 10 3
TEAD1_ENST00000638666 TEAD1 P28347 Transcriptional enhancer factor TEF-1 chr11 Not Cancer Driver No 1 hippie 52 157 24 24 1
TERT TERT O14746 Telomerase reverse transcriptase chr5 Census Yes 1 hippie 110 212 16 16 31
TET2 TET2 Q6N021 Methylcytosine dioxygenase TET2 chr4 Census, Compendium Yes 1 hippie 191 1663 176 176 1
TFCP2 TFCP2 Q12800 Alpha-globin transcription factor CP2 chr12 Not Cancer Driver No 1 hippie 68 169 23 23 0
THOC7 THOC7 Q6I9Y2 THO complex subunit 7 homolog chr3 Not Cancer Driver No 1 hippie 26 63 5 5 0
THRA THRA P10827 Thyroid hormone receptor alpha chr17 Not Cancer Driver No 1 hippie 69 207 30 30 2
TIAF1 MYO18A O95411 Putative TGFB1-induced anti-apoptotic factor 1 chr17 Not Cancer Driver No 1 hippie 16 30 5 5 0
TKT_ENST00000462138 TKT P29401 Transketolase chr3 Not Cancer Driver No 2 hippie, biogrid 66 86 7 7 1
TNS3 TNS3 Q68CZ2 Tensin-3 chr7 Not Cancer Driver No 1 hippie 238 864 143 143 0
TOMM40L_ENST00000367987 TOMM40L Q969M1 Mitochondrial import receptor subunit TOM40B chr1 Not Cancer Driver No 1 hippie 29 32 4 4 0
TP53BP1_ENST00000263801 TP53BP1 Q12888 TP53-binding protein 1 chr15 Not Cancer Driver No 1 hippie 227 1632 190 190 0
TPI1_ENST00000396705 TPI1 P60174 Triosephosphate isomerase chr12 Not Cancer Driver No 4 hippie, biogrid 40 15 2 2 7
TRAPPC2_ENST00000359680 TRAPPC2 P0DI81 Trafficking protein particle complex subunit 2 chrX Not Cancer Driver No 1 hippie 11 0 0 0 4
TRIM14 TRIM14 Q14142 Tripartite motif-containing protein 14 chr9 Not Cancer Driver No 1 hippie 36 93 7 7 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TRIM26 TRIM26 Q12899 Tripartite motif-containing protein 26 chr6 Not Cancer Driver No 1 hippie 67 153 16 16 0
TRIM37 TRIM37 O94972 E3 ubiquitin-protein ligase TRIM37 chr17 Not Cancer Driver No 1 hippie 119 492 60 60 3
TRIM44 TRIM44 Q96DX7 Tripartite motif-containing protein 44 chr11 Not Cancer Driver No 1 hippie 40 272 33 33 1
TRIM65 TRIM65 Q6PJ69 Tripartite motif-containing protein 65 chr17 Not Cancer Driver No 1 hippie 53 127 13 13 0
TSG101 TSG101 Q99816 Tumor susceptibility gene 101 protein chr11 Not Cancer Driver No 1 intact, hippie 46 159 23 23 0
TTN_ENST00000615779 TTN Q8WZ42 Titin chr2 Not Cancer Driver No 1 intact, hippie 7917 12926 2861 2861 10
TUBA1A TUBA1A Q71U36 Tubulin alpha-1A chain chr12 Not Cancer Driver No 1 hippie 59 52 11 11 8
TUBA4A TUBA4A P68366 Tubulin alpha-4A chain chr2 Not Cancer Driver No 1 hippie, biogrid 73 39 4 4 5
TXLNG TXLNG Q9NUQ3 Gamma-taxilin chrX Not Cancer Driver No 1 hippie 50 374 35 35 0
TXN TXN P10599 Thioredoxin chr9 Not Cancer Driver No 1 hippie, biogrid 6 0 0 0 0
TXNDC11 TXNDC11 Q6PKC3 Thioredoxin domain-containing protein 11 chr16 Not Cancer Driver No 1 hippie 81 179 17 17 0
TXNDC12 TXNDC12 O95881 Thioredoxin domain-containing protein 12 chr1 Not Cancer Driver No 1 hippie, biogrid 21 44 6 6 0
TXNDC16 TXNDC16 Q9P2K2 Thioredoxin domain-containing protein 16 chr14 Not Cancer Driver No 1 intact, hippie 98 63 4 4 0
UBAP1_ENST00000297661 UBAP1 Q9NZ09 Ubiquitin-associated protein 1 chr9 Not Cancer Driver No 1 hippie 58 267 31 31 0
UBD UBD O15205 Ubiquitin D chr6 Not Cancer Driver No 1 hippie 31 8 1 1 0
UBE2M UBE2M P61081 NEDD8-conjugating enzyme Ubc12 chr19 Not Cancer Driver No 1 hippie 30 32 6 6 0
UBE3A UBE3A Q05086 Ubiquitin-protein ligase E3A chr15 Not Cancer Driver No 1 hippie 141 136 22 22 0
UBQLN2 UBQLN2 Q9UHD9 Ubiquilin-2 chrX Not Cancer Driver No 1 hippie 82 581 79 79 8
UBR5 UBR5 O95071 E3 ubiquitin-protein ligase UBR5 chr8 Census, Compendium Yes 1 hippie 340 1296 162 162 0
UCHL1 UCHL1 P09936 Ubiquitin carboxyl-terminal hydrolase isozyme L1 chr4 Not Cancer Driver No 1 hippie, biogrid 33 34 7 7 4
UCHL3 UCHL3 P15374 Ubiquitin carboxyl-terminal hydrolase isozyme L3 chr13 Not Cancer Driver No 1 hippie, biogrid 26 61 3 3 0
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 hippie 109 141 24 24 0
UPF2_ENST00000357604 UPF2 Q9HAU5 Regulator of nonsense transcripts 2 chr10 Not Cancer Driver No 1 hippie 150 632 84 84 0
USP10_ENST00000219473 USP10 Q14694 Ubiquitin carboxyl-terminal hydrolase 10 chr16 Not Cancer Driver No 1 hippie 92 425 49 49 0
USP11 USP11 P51784 Ubiquitin carboxyl-terminal hydrolase 11 chrX Not Cancer Driver No 1 hippie 140 210 28 28 0
VCAM1 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 Not Cancer Driver No 2 intact, hippie 188 110 28 28 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
VPS26B VPS26B Q4G0F5 Vacuolar protein sorting-associated protein 26B chr11 Not Cancer Driver No 1 hippie 45 52 5 5 0
VPS35 VPS35 Q96QK1 Vacuolar protein sorting-associated protein 35 chr16 Not Cancer Driver No 1 hippie 68 99 9 9 1
WBP2_ENST00000254806 WBP2 Q969T9 WW domain-binding protein 2 chr17 Not Cancer Driver No 1 hippie 26 102 6 6 1
WDR1 WDR1 O75083 WD repeat-containing protein 1 chr4 Not Cancer Driver No 1 hippie, biogrid 66 30 7 7 2
WDR5 WDR5 P61964 WD repeat-containing protein 5 chr9 Not Cancer Driver No 1 hippie, biogrid 30 35 3 3 0
WDR81 WDR81 Q562E7 WD repeat-containing protein 81 chr17 Not Cancer Driver No 1 hippie 164 721 51 51 1
WWOX WWOX Q9NZC7 WW domain-containing oxidoreductase chr16 Not Cancer Driver No 1 hippie 79 108 9 9 3
WWP2 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 Not Cancer Driver No 1 hippie 112 422 57 57 0
XPO7 XPO7 Q9UIA9 Exportin-7 chr8 Not Cancer Driver No 1 hippie 132 59 8 8 0
XRCC6 XRCC6 P12956 X-ray repair cross-complementing protein 6 chr22 Not Cancer Driver No 1 hippie 66 140 12 12 0
XRN2 XRN2 Q9H0D6 5'-3' exoribonuclease 2 chr20 Not Cancer Driver No 1 hippie 129 427 63 63 0
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 Not Cancer Driver No 1 hippie 51 489 49 49 0
YWHAB_ENST00000353703 YWHAB P31946 14-3-3 protein beta/alpha chr20 Not Cancer Driver No 1 hippie, biogrid 22 109 4 4 0
YWHAQ YWHAQ P27348 14-3-3 protein theta chr2 Not Cancer Driver No 1 hippie 29 41 6 6 0
YWHAZ_ENST00000395956 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 4 intact, hippie, biogrid 30 81 10 10 0
ZBTB18_ENST00000622512 ZBTB18 Q99592 Zinc finger and BTB domain-containing protein 18 chr1 Not Cancer Driver No 1 intact 78 236 25 25 0
ZBTB44_ENST00000357899 ZBTB44 Q8NCP5 Zinc finger and BTB domain-containing protein 44 chr11 Not Cancer Driver No 1 hippie 68 266 35 35 0
ZC3H18_ENST00000301011 ZC3H18 Q86VM9 Zinc finger CCCH domain-containing protein 18 chr16 Not Cancer Driver No 1 hippie 139 929 134 134 0
ZC3H7A_ENST00000355758 ZC3H7A Q8IWR0 Zinc finger CCCH domain-containing protein 7A chr16 Not Cancer Driver No 1 hippie 91 224 23 23 0
ZFP36L2 ZFP36L2 P47974 mRNA decay activator protein ZFP36L2 chr2 Not Cancer Driver No 1 hippie 73 324 45 45 0
ZNF16 ZNF16 P17020 Zinc finger protein 16 chr8 Not Cancer Driver No 1 intact, hippie 99 293 40 40 0
ZNFX1_ENST00000371752 ZNFX1 Q9P2E3 NFX1-type zinc finger-containing protein 1 chr20 Not Cancer Driver No 1 hippie 228 354 49 49 0
ZP2 ZP2 Q05996 Zona pellucida sperm-binding protein 2 chr16 Not Cancer Driver No 1 intact, hippie 129 65 14 14 0
ZP3 ZP3 P21754 Zona pellucida sperm-binding protein 3 chr7 Not Cancer Driver No 1 intact, hippie 55 56 11 11 1
ZP4 ZP4 Q12836 Zona pellucida sperm-binding protein 4 chr1 Not Cancer Driver No 1 intact, hippie 189 46 15 15 0