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ENAH ,ENAH ,Q8N8S7
  • Uniprot Accession= Q8N8S7
  • Ensembl Transcript= ENST00000366844.7
  • Uniprot Name= ENAH
  • Name= Protein enabled homolog
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 22
  • Number of Interaction partner in biogrid: 22
  • Number of Interaction partner in hippie: 89
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AATK AATK Q6ZMQ8 Serine/threonine-protein kinase LMTK1 chr17 Not Cancer Driver No 1 intact 108 912 75 75 0
ABI1 ABI1 Q8IZP0 Abl interactor 1 chr10 Census, Compendium Yes 2 intact, hippie 55 360 39 39 0
ABI2_ENST00000261018 ABI2 Q9NYB9 Abl interactor 2 chr2 Not Cancer Driver No 1 hippie 56 361 38 38 0
ABI3 ABI3 Q9P2A4 ABI gene family member 3 chr17 Not Cancer Driver No 1 hippie 46 248 31 31 0
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 Census, Compendium Yes 1 hippie 139 604 73 73 2
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 1 hippie, biogrid 112 43 5 5 5
ACTC1 ACTC1 P68032 Actin, alpha cardiac muscle 1 chr15 Not Cancer Driver No 1 hippie 114 48 19 19 11
ACTL7A ACTL7A Q9Y615 Actin-like protein 7A chr9 Not Cancer Driver No 1 hippie 62 118 17 17 0
AJUBA AJUBA Q96IF1 LIM domain-containing protein ajuba chr14 Compendium Yes 1 hippie, biogrid 45 307 13 13 0
APBB1 APBB1 O00213 Amyloid beta precursor protein binding family B member 1 chr11 Not Cancer Driver No 1 hippie 105 399 58 58 0
ARHGAP27 ARHGAP27 Q6ZUM4 Rho GTPase-activating protein 27 chr17 Not Cancer Driver No 1 intact 91 516 57 57 0
ATOH1 ATOH1 Q92858 Transcription factor ATOH1 chr4 Not Cancer Driver No 1 hippie 63 327 55 55 0
ATXN3 ATXN3 P54252 Ataxin-3 chr14 Not Cancer Driver No 1 hippie 46 181 24 24 0
BAG2 BAG2 O95816 BAG family molecular chaperone regulator 2 chr6 Not Cancer Driver No 1 hippie, biogrid 17 112 9 9 0
BAIAP2 BAIAP2 Q9UQB8 Brain-specific angiogenesis inhibitor 1-associated protein 2 chr17 Not Cancer Driver No 1 hippie 85 330 52 52 0
BBS1 BBS1 Q8NFJ9 Bardet-Biedl syndrome 1 protein chr11 Not Cancer Driver No 1 hippie, biogrid 69 99 14 14 12
BCHE BCHE P06276 Cholinesterase chr3 Not Cancer Driver No 2 intact, hippie, biogrid 185 14 4 4 38
BICD2_ENST00000375512 BICD2 Q8TD16 Protein bicaudal D homolog 2 chr9 Not Cancer Driver No 1 hippie 115 546 73 73 10
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
CDC5L CDC5L Q99459 Cell division cycle 5-like protein chr6 Not Cancer Driver No 1 intact, hippie 100 618 77 77 0
CERS2_ENST00000368954 CERS2 Q96G23 Ceramide synthase 2 chr1 Not Cancer Driver No 1 hippie, biogrid 38 36 4 4 0
COPS4_ENST00000264389 COPS4 Q9BT78 COP9 signalosome complex subunit 4 chr4 Not Cancer Driver No 1 hippie 50 13 0 0 0
CTDP1 CTDP1 Q9Y5B0 RNA polymerase II subunit A C-terminal domain phosphatase chr18 Not Cancer Driver No 1 hippie 121 624 87 87 0
DCAF7 DCAF7 P61962 DDB1- and CUL4-associated factor 7 chr17 Not Cancer Driver No 2 intact, hippie 48 0 0 0 0
DLGAP4_ENST00000339266 DLGAP4 Q9Y2H0 Disks large-associated protein 4 chr20 Not Cancer Driver No 1 hippie, biogrid 170 883 157 157 0
DNAJB6 DNAJB6 O75190 DnaJ homolog subfamily B member 6 chr7 Not Cancer Driver No 1 hippie, biogrid 33 198 17 17 3
DNMBP DNMBP Q6XZF7 Dynamin-binding protein chr10 Not Cancer Driver No 1 hippie 208 758 92 92 0
DYRK1A_ENST00000644942 DYRK1A Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A chr21 Not Cancer Driver No 1 hippie 135 447 73 73 0
DYRK1B_ENST00000323039 DYRK1B Q9Y463 Dual specificity tyrosine-phosphorylation-regulated kinase 1B chr19 Not Cancer Driver No 1 hippie 77 319 38 38 2
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
ENAH ENAH Q8N8S7 Protein enabled homolog chr1 Not Cancer Driver No 1 hippie 65 514 61 61 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 334 1790 196 196 1
EVL_ENST00000402714 EVL Q9UI08 Ena/VASP-like protein chr14 Not Cancer Driver No 3 intact, hippie, biogrid 42 335 37 37 0
EZR EZR P15311 Ezrin chr6 Census Yes 1 intact, hippie 66 295 35 35 0
FAT1 FAT1 Q14517 Protocadherin Fat 1 chr4 Census, Compendium Yes 1 hippie 663 1051 126 126 0
FBLIM1_ENST00000375771 FBLIM1 Q8WUP2 Filamin-binding LIM protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 54 176 28 28 0
FGFR1OP CEP43 O95684 Centrosomal protein 43 chr6 Not Cancer Driver No 1 intact 43 272 33 33 0
FYB1_ENST00000515010 FYB1 O15117 FYN-binding protein 1 chr5 Not Cancer Driver No 1 hippie 176 687 161 161 0
GPHN_ENST00000315266 GPHN Q9NQX3 Gephyrin chr14 Census Yes 1 hippie 126 305 41 41 2
HECW2_ENST00000644256 HECW2 Q9P2P5 E3 ubiquitin-protein ligase HECW2 chr2 Not Cancer Driver No 1 hippie 348 845 195 195 4
HEXIM1 HEXIM1 O94992 Protein HEXIM1 chr17 Not Cancer Driver No 1 hippie 40 352 40 40 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 Not Cancer Driver No 1 intact, hippie 25 203 20 20 0
HNRNPH1 HNRNPH1 P31943 Heterogeneous nuclear ribonucleoprotein H chr5 Not Cancer Driver No 1 hippie 51 169 29 29 0
HNRNPL HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 89 283 29 29 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 intact, hippie 149 251 52 52 0
KIAA1522_ENST00000373480 KIAA1522 Q9P206 Uncharacterized protein KIAA1522 chr1 Not Cancer Driver No 1 hippie, biogrid 143 1007 140 140 0
KLHDC3 KLHDC3 Q9BQ90 Kelch domain-containing protein 3 chr6 Not Cancer Driver No 1 hippie 43 12 1 1 0
LGALS3BP LGALS3BP Q08380 Galectin-3-binding protein chr17 Not Cancer Driver No 1 hippie 62 9 0 0 0
LPIN3_ENST00000373257 LPIN3 Q9BQK8 Phosphatidate phosphatase LPIN3 chr20 Not Cancer Driver No 1 hippie, biogrid 91 472 50 50 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 519 90 17 17 23
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 Census, Compendium Yes 1 intact, hippie 62 2 0 0 7
MYO10 MYO10 Q9HD67 Unconventional myosin-X chr5 Not Cancer Driver No 1 intact, hippie 296 418 59 59 0
NAA40 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 22 30 3 3 0
NECTIN4 NECTIN4 Q96NY8 Nectin-4 chr1 Not Cancer Driver No 2 intact, hippie 92 279 50 50 1
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
OSGEP OSGEP Q9NPF4 tRNA N6-adenosine threonylcarbamoyltransferase chr14 Not Cancer Driver No 1 hippie, biogrid 46 32 4 4 14
PARL PARL Q9H300 Presenilins-associated rhomboid-like protein, mitochondrial chr3 Not Cancer Driver No 3 intact, hippie, biogrid 49 28 5 5 0
PFN1 PFN1 P07737 Profilin-1 chr17 Not Cancer Driver No 2 hippie, biogrid 16 7 1 1 3
PFN2 PFN2 P35080 Profilin-2 chr3 Not Cancer Driver No 2 intact, hippie, biogrid 20 0 0 0 0
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 30 157 13 13 0
PPM1K PPM1K Q8N3J5 Protein phosphatase 1K, mitochondrial chr4 Not Cancer Driver No 1 intact, hippie 59 62 12 12 0
PPP6R3_ENST00000393800 PPP6R3 Q5H9R7 Serine/threonine-protein phosphatase 6 regulatory subunit 3 chr11 Not Cancer Driver No 1 hippie 108 389 52 52 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 Not Cancer Driver No 1 hippie 110 78 15 15 31
PRMT6 PRMT6 Q96LA8 Protein arginine N-methyltransferase 6 chr1 Not Cancer Driver No 3 hippie, biogrid 43 71 7 7 0
PRPF4 PRPF4 O43172 U4/U6 small nuclear ribonucleoprotein Prp4 chr9 Not Cancer Driver No 1 hippie 61 152 15 15 2
PRPF40A PRPF40A O75400 Pre-mRNA-processing factor 40 homolog A chr2 Not Cancer Driver No 1 hippie 83 694 57 57 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 Census, Compendium Yes 1 hippie 66 2 1 1 6
RAD51_ENST00000267868 RAD51 Q06609 DNA repair protein RAD51 homolog 1 chr15 Not Cancer Driver No 1 hippie 42 47 5 5 3
RAPH1 RAPH1 Q70E73 Ras-associated and pleckstrin homology domains-containing protein 1 chr2 Not Cancer Driver No 1 hippie 123 962 98 98 0
ROBO4 ROBO4 Q8WZ75 Roundabout homolog 4 chr11 Not Cancer Driver No 1 hippie 194 697 133 133 1
RPS6KA1_ENST00000374168 RPS6KA1 Q15418 Ribosomal protein S6 kinase alpha-1 chr1 Not Cancer Driver No 1 intact, hippie 94 178 32 32 0
SH3RF1 SH3RF1 Q7Z6J0 E3 ubiquitin-protein ligase SH3RF1 chr4 Not Cancer Driver No 1 hippie 109 586 72 72 0
SMURF2 SMURF2 Q9HAU4 E3 ubiquitin-protein ligase SMURF2 chr17 Not Cancer Driver No 1 hippie 87 242 28 28 0
SNW1_ENST00000261531 SNW1 Q13573 SNW domain-containing protein 1 chr14 Not Cancer Driver No 1 hippie 62 488 56 56 0
SPTA1_ENST00000368147 SPTA1 P02549 Spectrin alpha chain, erythrocytic 1 chr1 Not Cancer Driver No 1 intact, hippie 1046 707 294 294 21
TACC3 TACC3 Q9Y6A5 Transforming acidic coiled-coil-containing protein 3 chr4 Not Cancer Driver No 2 hippie, biogrid 98 707 81 81 0
TERF2IP TERF2IP Q9NYB0 Telomeric repeat-binding factor 2-interacting protein 1 chr16 Not Cancer Driver No 1 hippie 28 310 16 16 0
TES TES Q9UGI8 Testin chr7 Not Cancer Driver No 1 hippie 56 100 7 7 0
TMOD3 TMOD3 Q9NYL9 Tropomodulin-3 chr15 Not Cancer Driver No 2 intact, hippie, biogrid 40 190 24 24 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2891 282 1466 1466 83
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 87 430 41 41 0
VASP VASP P50552 Vasodilator-stimulated phosphoprotein chr19 Not Cancer Driver No 5 intact, hippie, biogrid 39 335 34 34 0
VCL VCL P18206 Vinculin chr10 Not Cancer Driver No 1 hippie, biogrid 114 673 80 80 2
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
WAS WAS P42768 Wiskott-Aldrich syndrome protein chrX Census, Compendium Yes 1 hippie 75 400 55 55 30
WWOX WWOX Q9NZC7 WW domain-containing oxidoreductase chr16 Not Cancer Driver No 1 hippie 79 108 9 9 3
XIRP1 XIRP1 Q702N8 Xin actin-binding repeat-containing protein 1 chr3 Not Cancer Driver No 1 hippie 326 1660 301 301 0
XPO1_ENST00000406957 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie 140 33 9 9 0
XPO6 XPO6 Q96QU8 Exportin-6 chr16 Not Cancer Driver No 1 hippie 133 29 1 1 0
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 Not Cancer Driver No 1 hippie 51 489 49 49 0
ZYX ZYX Q15942 Zyxin chr7 Not Cancer Driver No 4 hippie, biogrid 83 385 52 52 0