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EMC1 ,EMC1 ,Q8N766
  • Number of Interaction partner in intact: 42
  • Number of Interaction partner in biogrid: 98
  • Number of Interaction partner in hippie: 370
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACAD9 ACAD9 Q9H845 Complex I assembly factor ACAD9, mitochondrial chr3 Not Cancer Driver No 1 hippie 69 28 5 5 12
ACADVL_ENST00000356839 ACADVL P49748 Very long-chain specific acyl-CoA dehydrogenase, mitochondrial chr17 Not Cancer Driver No 1 hippie 50 100 5 5 37
ACLY_ENST00000590151 ACLY P53396 ATP-citrate synthase chr17 Not Cancer Driver No 1 hippie 120 114 12 12 0
ACSL3 ACSL3 O95573 Fatty acid CoA ligase Acsl3 chr2 Census, Compendium Yes 1 hippie 89 47 7 7 0
ADPGK ADPGK Q9BRR6 ADP-dependent glucokinase chr15 Not Cancer Driver No 1 hippie, biogrid 38 24 0 0 0
AFG3L2 AFG3L2 Q9Y4W6 AFG3-like protein 2 chr18 Not Cancer Driver No 1 hippie 72 162 10 10 22
AGL_ENST00000361915 AGL P35573 Glycogen debranching enzyme chr1 Not Cancer Driver No 1 hippie 182 143 23 23 1
AHNAK AHNAK Q09666 Neuroblast differentiation-associated protein AHNAK chr11 Not Cancer Driver No 1 hippie 805 5777 794 794 0
AHNAK2 AHNAK2 Q8IVF2 Protein AHNAK2 chr14 Not Cancer Driver No 1 hippie 1074 5470 1018 1018 0
AIMP1_ENST00000442366 AIMP1 Q12904 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 chr4 Not Cancer Driver No 1 hippie 31 161 19 19 0
AK2 AK2 P54819 Adenylate kinase 2, mitochondrial chr1 Not Cancer Driver No 1 hippie 23 76 12 12 2
AKAP1_ENST00000539273 AKAP1 Q92667 A-kinase anchor protein 1, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 107 537 67 67 0
ALDH7A1 ALDH7A1 P49419 Alpha-aminoadipic semialdehyde dehydrogenase chr5 Not Cancer Driver No 1 hippie 52 26 1 1 8
ALDOA_ENST00000643777 ALDOA P04075 Fructose-bisphosphate aldolase A chr16 Not Cancer Driver No 1 hippie 47 65 9 9 3
ANP32B ANP32B Q92688 Acidic leucine-rich nuclear phosphoprotein 32 family member B chr9 Not Cancer Driver No 1 hippie 22 117 12 12 0
ANPEP ANPEP P15144 Aminopeptidase N chr15 Not Cancer Driver No 1 hippie, biogrid 175 109 26 26 0
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 Not Cancer Driver No 1 hippie 59 61 12 12 0
ANXA2_ENST00000396024 ANXA2 P07355 Annexin A2 chr15 Not Cancer Driver No 1 hippie 49 20 4 4 0
ANXA3 ANXA3 P12429 Annexin A3 chr4 Not Cancer Driver No 1 hippie 53 22 4 4 0
ANXA5 ANXA5 P08758 Annexin A5 chr4 Not Cancer Driver No 1 hippie 50 33 5 5 0
APOA2 APOA2 P02652 Apolipoprotein A-II chr1 Not Cancer Driver No 1 hippie, biogrid 13 0 0 0 0
APOC3 APOC3 P02656 Apolipoprotein C-III chr11 Not Cancer Driver No 1 hippie, biogrid 14 12 2 2 1
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 Not Cancer Driver No 1 intact, hippie 18 5 0 0 0
ARMCX3_ENST00000537169 ARMCX3 Q9UH62 Armadillo repeat-containing X-linked protein 3 chrX Not Cancer Driver No 1 hippie, biogrid 39 77 7 7 0
ASS1_ENST00000352480 ASS1 P00966 Argininosuccinate synthase chr9 Not Cancer Driver No 1 hippie 65 63 8 8 86
ATAD1_ENST00000328142 ATAD1 Q8NBU5 Outer mitochondrial transmembrane helix translocase chr10 Not Cancer Driver No 1 hippie 32 71 3 3 0
ATG2A ATG2A Q2TAZ0 Autophagy-related protein 2 homolog A chr11 Not Cancer Driver No 1 intact, hippie 228 887 124 124 0
ATP13A1 ATP13A1 Q9HD20 Endoplasmic reticulum transmembrane helix translocase chr19 Not Cancer Driver No 1 hippie 131 95 15 15 0
ATP1A1_ENST00000295598 ATP1A1 P05023 Sodium/potassium-transporting ATPase subunit alpha-1 chr1 Census Yes 1 hippie 115 115 16 16 6
ATP1B3 ATP1B3 P54709 Sodium/potassium-transporting ATPase subunit beta-3 chr3 Not Cancer Driver No 3 hippie, biogrid 36 6 1 1 0
ATP1B4 ATP1B4 Q9UN42 Protein ATP1B4 chrX Not Cancer Driver No 3 intact, hippie, biogrid 85 79 18 18 0
ATP2A2 ATP2A2 P16615 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 chr12 Not Cancer Driver No 1 hippie 136 78 14 14 41
ATP2B1_ENST00000261173 ATP2B1 P20020 Plasma membrane calcium-transporting ATPase 1 chr12 Not Cancer Driver No 1 hippie 143 293 42 42 0
ATP2B4_ENST00000341360 ATP2B4 P23634-2 Isoform XA of Plasma membrane calcium-transporting ATPase 4 chr1 Not Cancer Driver No 1 hippie 145 219 21 21 0
ATP2C1_ENST00000508532 ATP2C1 P98194 Calcium-transporting ATPase type 2C member 1 chr3 Not Cancer Driver No 1 hippie 125 44 5 5 20
ATP5F1A_ENST00000282050 ATP5F1A P25705 ATP synthase subunit alpha, mitochondrial chr18 Not Cancer Driver No 1 hippie 66 23 5 5 2
ATP5F1B ATP5F1B P06576 ATP synthase subunit beta, mitochondrial chr12 Not Cancer Driver No 1 hippie 60 85 8 8 0
ATP6AP1 ATP6AP1 Q15904 V-type proton ATPase subunit S1 chrX Not Cancer Driver No 2 hippie, biogrid 67 0 0 0 4
ATP6AP2 ATP6AP2 O75787 Renin receptor chrX Not Cancer Driver No 1 hippie 56 0 0 0 2
ATP6V0A1_ENST00000343619 ATP6V0A1 Q93050 V-type proton ATPase 116 kDa subunit a 1 chr17 Not Cancer Driver No 1 hippie 98 85 14 14 0
ATP6V0A2 ATP6V0A2 Q9Y487 V-type proton ATPase 116 kDa subunit a 2 chr12 Not Cancer Driver No 1 hippie 88 36 6 6 0
ATP6V0D1 ATP6V0D1 P61421 V-type proton ATPase subunit d 1 chr16 Not Cancer Driver No 1 hippie 40 0 0 0 0
AURKA_ENST00000395915 AURKA O14965 Aurora kinase A chr20 Not Cancer Driver No 1 biogrid 36 178 21 21 0
BASP1_ENST00000616743 BASP1 P80723 Brain acid soluble protein 1 chr5 Not Cancer Driver No 1 hippie 39 227 39 39 0
BCAP31_ENST00000345046 BCAP31 P51572 B-cell receptor-associated protein 31 chrX Not Cancer Driver No 1 hippie, biogrid 37 104 14 14 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
BSG BSG P35613 Basigin chr19 Not Cancer Driver No 1 hippie, biogrid 43 123 17 17 0
BTNL3 BTNL3 Q6UXE8 Butyrophilin-like protein 3 chr5 Not Cancer Driver No 1 hippie, biogrid 79 50 13 13 0
BZW2_ENST00000258761 BZW2 Q9Y6E2 eIF5-mimic protein 1 chr7 Not Cancer Driver No 1 hippie 41 58 8 8 0
CA9 CA9 Q16790 Carbonic anhydrase 9 chr9 Not Cancer Driver No 1 hippie 72 274 50 50 0
CALM1 CALM1 P0DP23 Calmodulin-1 chr14 Not Cancer Driver No 1 hippie 19 115 15 15 7
CALR CALR P27797 Calreticulin chr19 Census Yes 1 hippie 45 245 31 31 0
CALR3 CALR3 Q96L12 Calreticulin-3 chr19 Not Cancer Driver No 2 hippie, biogrid 60 101 16 16 0
CALU_ENST00000249364 CALU O43852 Calumenin chr7 Not Cancer Driver No 2 hippie, biogrid 34 130 12 12 0
CANX_ENST00000504734 CANX P27824 Calnexin chr5 Not Cancer Driver No 2 intact, hippie 65 334 38 38 0
CAPNS1 CAPNS1 P04632 Calpain small subunit 1 chr19 Not Cancer Driver No 1 hippie 30 58 5 5 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 Not Cancer Driver No 1 hippie 30 2 0 0 0
CCT7 CCT7 Q99832 T-complex protein 1 subunit eta chr2 Not Cancer Driver No 1 hippie 59 36 6 6 0
CD109 CD109 Q6YHK3 CD109 antigen chr6 Not Cancer Driver No 1 hippie 204 54 11 11 0
CD274 CD274 Q9NZQ7 Programmed cell death 1 ligand 1 chr9 Census Yes 1 hippie 29 54 9 9 0
CD55_ENST00000367064 CD55 P08174 Complement decay-accelerating factor chr1 Not Cancer Driver No 1 hippie 45 128 13 13 1
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 39 23 2 2 1
CENPH CENPH Q9H3R5 Centromere protein H chr5 Not Cancer Driver No 1 hippie 28 85 7 7 0
CHCHD2 CHCHD2 Q9Y6H1 Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 chr7 Not Cancer Driver No 1 hippie 24 114 21 21 1
CKAP4 CKAP4 Q07065 Cytoskeleton-associated protein 4 chr12 Not Cancer Driver No 1 hippie 73 409 55 55 0
CLEC4D CLEC4D Q8WXI8 C-type lectin domain family 4 member D chr12 Not Cancer Driver No 1 hippie, biogrid 59 17 3 3 0
CLEC4E CLEC4E Q9ULY5 C-type lectin domain family 4 member E chr12 Not Cancer Driver No 1 hippie, biogrid 56 5 2 2 0
COASY_ENST00000421097 COASY Q13057 Bifunctional coenzyme A synthase chr17 Not Cancer Driver No 1 hippie 57 50 4 4 1
COPS5 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 Not Cancer Driver No 1 hippie 36 32 7 7 0
COX4I1 COX4I1 P13073 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 17 5 1 1 1
COX5B COX5B P10606 Cytochrome c oxidase subunit 5B, mitochondrial chr2 Not Cancer Driver No 1 hippie 16 58 6 6 0
CPS1_ENST00000233072 CPS1 P31327 Carbamoyl-phosphate synthase [ammonia], mitochondrial chr2 Not Cancer Driver No 1 hippie 368 73 22 22 140
CPSF3 CPSF3 Q9UKF6 Cleavage and polyadenylation specificity factor subunit 3 chr2 Not Cancer Driver No 1 hippie 78 56 9 9 0
CPT1A_ENST00000539743 CPT1A P50416 Carnitine O-palmitoyltransferase 1, liver isoform chr11 Not Cancer Driver No 1 hippie 144 62 10 10 15
CSE1L CSE1L P55060 Exportin-2 chr20 Not Cancer Driver No 1 hippie 109 32 5 5 0
CTDNEP1_ENST00000318988 CTDNEP1 O95476 CTD nuclear envelope phosphatase 1 chr17 Not Cancer Driver No 1 intact, hippie 20 0 0 0 0
CTSL CTSL P07711 Procathepsin L chr9 Not Cancer Driver No 1 hippie, biogrid 47 34 4 4 0
CTSS CTSS P25774 Cathepsin S chr1 Not Cancer Driver No 1 hippie, biogrid 54 0 0 0 0
CUL3 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 intact, hippie 123 167 23 23 3
CUL7_ENST00000265348 CUL7 Q14999 Cullin-7 chr6 Not Cancer Driver No 1 hippie 188 372 41 41 3
CXADR CXADR P78310 Coxsackievirus and adenovirus receptor chr21 Not Cancer Driver No 1 hippie 51 98 19 19 0
CYB5B CYB5B O43169 Cytochrome b5 type B chr16 Not Cancer Driver No 1 hippie 17 58 2 2 0
CYB5R1 CYB5R1 Q9UHQ9 NADH-cytochrome b5 reductase 1 chr1 Not Cancer Driver No 1 hippie 43 22 1 1 0
CYB5R3_ENST00000352397 CYB5R3 P00387 NADH-cytochrome b5 reductase 3 chr22 Not Cancer Driver No 1 hippie 42 24 3 3 9
CYC1 CYC1 P08574 Cytochrome c1, heme protein, mitochondrial chr8 Not Cancer Driver No 1 hippie 65 35 8 8 2
DDOST_ENST00000375048 DDOST P39656 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit chr1 Not Cancer Driver No 1 hippie 34 13 3 3 1
DERL1 DERL1 Q9BUN8 Derlin-1 chr8 Not Cancer Driver No 1 intact, hippie 28 11 1 1 0
DERL2 DERL2 Q9GZP9 Derlin-2 chr17 Not Cancer Driver No 1 intact, hippie 19 15 1 1 0
DISC1_ENST00000439617 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 Not Cancer Driver No 1 intact, hippie 132 514 82 82 0
DNAJA2 DNAJA2 O60884 DnaJ homolog subfamily A member 2 chr16 Not Cancer Driver No 1 hippie 50 174 27 27 0
DNAJB11_ENST00000265028 DNAJB11 Q9UBS4 DnaJ homolog subfamily B member 11 chr3 Not Cancer Driver No 1 hippie, biogrid 52 141 21 21 2
DNAJB12_ENST00000444643 DNAJB12 Q9NXW2 DnaJ homolog subfamily B member 12 chr10 Not Cancer Driver No 1 hippie, biogrid 43 227 20 20 0
DNAJB9 DNAJB9 Q9UBS3 DnaJ homolog subfamily B member 9 chr7 Not Cancer Driver No 1 hippie, biogrid 30 107 15 15 0
DNAJC1 DNAJC1 Q96KC8 DnaJ homolog subfamily C member 1 chr10 Not Cancer Driver No 1 hippie, biogrid 60 315 44 44 0
DNAJC10 DNAJC10 Q8IXB1 DnaJ homolog subfamily C member 10 chr2 Not Cancer Driver No 1 hippie, biogrid 110 36 3 3 0
DNAJC14_ENST00000317287 DNAJC14 Q6Y2X3 DnaJ homolog subfamily C member 14 chr12 Not Cancer Driver No 1 hippie, biogrid 90 372 53 53 0
DNAJC16 DNAJC16 Q9Y2G8 DnaJ homolog subfamily C member 16 chr1 Not Cancer Driver No 1 hippie, biogrid 84 63 2 2 0
DNAJC22_ENST00000395069 DNAJC22 Q8N4W6 DnaJ homolog subfamily C member 22 chr12 Not Cancer Driver No 1 hippie, biogrid 50 11 1 1 0
DNAJC25 DNAJC25 Q9H1X3 DnaJ homolog subfamily C member 25 chr9 Not Cancer Driver No 1 hippie, biogrid 37 39 3 3 0
DNAJC3 DNAJC3 Q13217 DnaJ homolog subfamily C member 3 chr13 Not Cancer Driver No 1 hippie, biogrid 60 131 17 17 0
DNAJC30 DNAJC30 Q96LL9 DnaJ homolog subfamily C member 30, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 25 83 7 7 3
DPP4 DPP4 P27487 Dipeptidyl peptidase 4 chr2 Not Cancer Driver No 1 hippie, biogrid 151 8 1 1 0
DYNC1H1 DYNC1H1 Q14204 Cytoplasmic dynein 1 heavy chain 1 chr14 Not Cancer Driver No 1 hippie 505 495 62 62 21
ECHS1 ECHS1 P30084 Enoyl-CoA hydratase, mitochondrial chr10 Not Cancer Driver No 1 hippie 51 7 1 1 14
EDEM3 EDEM3 Q9BZQ6 ER degradation-enhancing alpha-mannosidase-like protein 3 chr1 Not Cancer Driver No 1 hippie 108 298 38 38 0
EFTUD2 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 132 179 30 30 3
EMC1 EMC1 Q8N766 ER membrane protein complex subunit 1 chr1 Not Cancer Driver No 2 hippie, biogrid 107 59 6 6 2
EMC10 EMC10 Q5UCC4 ER membrane protein complex subunit 10 chr19 Not Cancer Driver No 2 intact, hippie, biogrid 25 109 15 15 0
EMC2 EMC2 Q15006 ER membrane protein complex subunit 2 chr8 Not Cancer Driver No 6 intact, hippie, biogrid 48 29 3 3 0
EMC3 EMC3 Q9P0I2 ER membrane protein complex subunit 3 chr3 Not Cancer Driver No 3 intact, hippie, biogrid 26 31 6 6 0
EMC4 EMC4 Q5J8M3 ER membrane protein complex subunit 4 chr15 Not Cancer Driver No 2 intact, hippie, biogrid 15 17 2 2 0
EMC6 EMC6 Q9BV81 ER membrane protein complex subunit 6 chr17 Not Cancer Driver No 1 hippie, biogrid 4 0 0 0 0
EMC7 EMC7 Q9NPA0 ER membrane protein complex subunit 7 chr15 Not Cancer Driver No 3 intact, hippie, biogrid 35 54 10 10 0
EMC8 EMC8 O43402 ER membrane protein complex subunit 8 chr16 Not Cancer Driver No 2 intact, hippie, biogrid 15 20 0 0 0
EMC9_ENST00000216799 EMC9 Q9Y3B6 ER membrane protein complex subunit 9 chr14 Not Cancer Driver No 2 intact, hippie, biogrid 22 17 1 1 0
ENO1 ENO1 P06733 Alpha-enolase chr1 Not Cancer Driver No 1 intact, hippie 51 21 2 2 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 334 1790 196 196 1
EPHA10 EPHA10 Q5JZY3 Ephrin type-A receptor 10 chr1 Not Cancer Driver No 1 intact 171 225 41 41 0
EPHA7 EPHA7 Q15375 Ephrin type-A receptor 7 chr6 Census, Compendium Yes 2 intact, hippie, biogrid 280 71 15 15 0
EPHA8 EPHA8 P29322 Ephrin type-A receptor 8 chr1 Not Cancer Driver No 1 intact 197 121 17 17 0
ERLIN1 ERLIN1 O75477 Erlin-1 chr10 Not Cancer Driver No 1 hippie 29 46 4 4 1
ERLIN2_ENST00000519638 ERLIN2 O94905 Erlin-2 chr8 Not Cancer Driver No 1 hippie 38 22 3 3 0
ERMP1 ERMP1 Q7Z2K6 Endoplasmic reticulum metallopeptidase 1 chr9 Not Cancer Driver No 1 hippie 80 93 4 4 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
ETFA ETFA P13804 Electron transfer flavoprotein subunit alpha, mitochondrial chr15 Not Cancer Driver No 1 hippie 30 34 2 2 3
EXTL2 EXTL2 Q9UBQ6 Exostosin-like 2 chr1 Not Cancer Driver No 1 hippie 50 0 0 0 0
FAF2 FAF2 Q96CS3 FAS-associated factor 2 chr5 Not Cancer Driver No 1 hippie 54 171 16 16 0
FAM162A FAM162A Q96A26 Protein FAM162A chr3 Not Cancer Driver No 1 hippie 18 53 8 8 0
FASN FASN P49327 Fatty acid synthase chr17 Not Cancer Driver No 1 hippie 291 309 42 42 0
FBXO2 FBXO2 Q9UK22 F-box only protein 2 chr1 Not Cancer Driver No 1 hippie, biogrid 21 75 1 1 0
FBXO6 FBXO6 Q9NRD1 F-box only protein 6 chr1 Not Cancer Driver No 1 hippie 31 27 3 3 0
FDPS_ENST00000368356 FDPS P14324 Farnesyl pyrophosphate synthase chr1 Not Cancer Driver No 1 biogrid 66 0 0 0 1
FIS1 FIS1 Q9Y3D6 Mitochondrial fission 1 protein chr7 Not Cancer Driver No 1 hippie, biogrid 25 6 0 0 0
FKBP10 FKBP10 Q96AY3 Peptidyl-prolyl cis-trans isomerase FKBP10 chr17 Not Cancer Driver No 1 hippie 60 134 8 8 3
FKBP8_ENST00000222308 FKBP8 Q14318 Peptidyl-prolyl cis-trans isomerase FKBP8 chr19 Not Cancer Driver No 1 hippie, biogrid 71 160 25 25 0
FLOT1 FLOT1 O75955 Flotillin-1 chr6 Not Cancer Driver No 1 hippie, biogrid 43 122 15 15 0
FOLR1_ENST00000393681 FOLR1 P15328 Folate receptor alpha chr11 Not Cancer Driver No 1 hippie 41 13 3 3 0
FXR1 FXR1 P51114 Fragile X mental retardation syndrome-related protein 1 chr3 Not Cancer Driver No 1 hippie 88 312 53 53 0
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 Not Cancer Driver No 1 hippie 92 70 13 13 0
GALNT2 GALNT2 Q10471 Polypeptide N-acetylgalactosaminyltransferase 2 chr1 Not Cancer Driver No 1 hippie 94 122 22 22 2
GANAB_ENST00000356638 GANAB Q14697 Neutral alpha-glucosidase AB chr11 Not Cancer Driver No 1 hippie 129 132 20 20 3
GAPDH GAPDH P04406 Glyceraldehyde-3-phosphate dehydrogenase chr12 Not Cancer Driver No 1 hippie 39 24 3 3 0
GCN1 GCN1 Q92616 eIF-2-alpha kinase activator GCN1 chr12 Not Cancer Driver No 1 hippie 327 117 16 16 0
GDI2 GDI2 P50395 Rab GDP dissociation inhibitor beta chr10 Not Cancer Driver No 1 hippie 49 23 2 2 0
GFPT1 GFPT1 Q06210 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 chr2 Not Cancer Driver No 1 hippie 81 75 8 8 13
GNAI1 GNAI1 P63096 Guanine nucleotide-binding protein G(i) subunit alpha-1 chr7 Not Cancer Driver No 1 hippie 52 11 3 3 0
GNAI3 GNAI3 P08754 Guanine nucleotide-binding protein G(i) subunit alpha-3 chr1 Not Cancer Driver No 1 hippie 42 11 0 0 1
GOSR2_ENST00000640051 GOSR2 O14653 Golgi SNAP receptor complex member 2 chr17 Not Cancer Driver No 1 hippie 25 103 17 17 1
GPI_ENST00000644934 GPI P06744 Glucose-6-phosphate isomerase chr19 Not Cancer Driver No 1 hippie 77 73 11 11 24
GTF2H4 GTF2H4 Q92759 General transcription factor IIH subunit 4 chr6 Not Cancer Driver No 1 biogrid 46 30 5 5 0
GYS1 GYS1 P13807 Glycogen [starch] synthase, muscle chr19 Not Cancer Driver No 1 hippie 98 127 18 18 0
HDGF_ENST00000357325 HDGF P51858 Hepatoma-derived growth factor chr1 Not Cancer Driver No 1 hippie 35 203 29 29 0
HK1_ENST00000359426 HK1 P19367 Hexokinase-1 chr10 Not Cancer Driver No 1 hippie, biogrid 127 75 16 16 6
HLA-A_ENST00000376809 HLA-A P04439 HLA class I histocompatibility antigen, A alpha chain chr6 Census, Compendium Yes 1 hippie 128 125 60 60 0
HLA-C HLA-C P10321 HLA class I histocompatibility antigen, C alpha chain chr6 Not Cancer Driver No 1 hippie 104 175 58 58 0
HM13_ENST00000340852 HM13 Q8TCT9 Minor histocompatibility antigen H13 chr20 Not Cancer Driver No 1 hippie 42 61 6 6 0
HSCB HSCB Q8IWL3 Iron-sulfur cluster co-chaperone protein HscB chr22 Not Cancer Driver No 1 intact, hippie 36 25 6 6 0
HSPA13 HSPA13 P48723 Heat shock 70 kDa protein 13 chr21 Not Cancer Driver No 1 hippie, biogrid 74 48 7 7 0
HSPA4 HSPA4 P34932 Heat shock 70 kDa protein 4 chr5 Not Cancer Driver No 1 hippie 80 351 24 24 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 Not Cancer Driver No 1 hippie, biogrid 73 282 35 35 0
HUWE1_ENST00000262854 HUWE1 Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 chrX Not Cancer Driver No 1 hippie 669 2091 329 329 21
ICAM1 ICAM1 P05362 Intercellular adhesion molecule 1 chr19 Not Cancer Driver No 1 hippie 61 251 28 28 0
ILF2 ILF2 Q12905 Interleukin enhancer-binding factor 2 chr1 Not Cancer Driver No 1 hippie, biogrid 36 92 9 9 0
ILF3_ENST00000590261 ILF3 Q12906 Interleukin enhancer-binding factor 3 chr19 Not Cancer Driver No 1 hippie, biogrid 103 674 82 82 0
IMPDH2 IMPDH2 P12268 Inosine-5'-monophosphate dehydrogenase 2 chr3 Not Cancer Driver No 1 hippie 70 6 1 1 0
INSR INSR P06213 Insulin receptor chr19 Not Cancer Driver No 1 intact 190 280 57 57 64
ISG15 ISG15 P05161 Ubiquitin-like protein ISG15 chr1 Not Cancer Driver No 1 hippie 12 24 2 2 0
ITGB1_ENST00000302278 ITGB1 P05556 Integrin beta-1 chr10 Not Cancer Driver No 1 hippie 103 84 10 10 0
KIDINS220 KIDINS220 Q9ULH0 Kinase D-interacting substrate of 220 kDa chr2 Not Cancer Driver No 1 hippie 245 683 113 113 0
KLHL22 KLHL22 Q53GT1 Kelch-like protein 22 chr22 Not Cancer Driver No 1 hippie, biogrid 90 50 8 8 0
KRAS KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 1 hippie 788 7 2 2 27
KSR1_ENST00000644974 KSR1 Q8IVT5 Kinase suppressor of Ras 1 chr17 Not Cancer Driver No 1 intact, hippie 114 404 58 58 0
L1CAM L1CAM P32004 Neural cell adhesion molecule L1 chrX Not Cancer Driver No 1 hippie 228 442 75 75 54
LAMP1 LAMP1 P11279 Lysosome-associated membrane glycoprotein 1 chr13 Not Cancer Driver No 1 hippie 47 93 10 10 0
LDHA_ENST00000422447 LDHA P00338 L-lactate dehydrogenase A chain chr11 Not Cancer Driver No 1 hippie 40 9 0 0 0
LMAN1 LMAN1 P49257 Protein ERGIC-53 chr18 Not Cancer Driver No 1 hippie 63 222 25 25 1
LMAN2 LMAN2 Q12907 Vesicular integral-membrane protein VIP36 chr5 Not Cancer Driver No 1 hippie 53 36 8 8 0
LMBR1L LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 57 4 0 0 0
LMNA LMNA P02545 Prelamin-A/C chr1 Census Yes 1 intact, hippie 68 544 49 49 131
LONP1 LONP1 P36776 Lon protease homolog, mitochondrial chr19 Not Cancer Driver No 1 hippie 99 175 15 15 10
LRRC59 LRRC59 Q96AG4 Leucine-rich repeat-containing protein 59 chr17 Not Cancer Driver No 1 hippie, biogrid 33 122 15 15 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 519 90 17 17 23
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 Census Yes 1 hippie 95 84 12 12 0
MAP1LC3B MAP1LC3B Q9GZQ8 Microtubule-associated proteins 1A/1B light chain 3B chr16 Not Cancer Driver No 1 hippie 10 17 1 1 0
MBOAT7 MBOAT7 Q96N66 Lysophospholipid acyltransferase 7 chr19 Not Cancer Driver No 1 hippie 69 25 3 3 0
MBTPS2 MBTPS2 O43462 Membrane-bound transcription factor site-2 protease chrX Not Cancer Driver No 1 biogrid 63 16 4 4 9
MDH1_ENST00000233114 MDH1 P40925 Malate dehydrogenase, cytoplasmic chr2 Not Cancer Driver No 1 hippie 41 18 2 2 1
MDH2 MDH2 P40926 Malate dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 hippie 39 8 1 1 3
MED1 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 Not Cancer Driver No 1 biogrid 162 1104 117 117 0
MED23 MED23 Q9ULK4 Mediator of RNA polymerase II transcription subunit 23 chr6 Not Cancer Driver No 1 biogrid 158 28 2 2 1
MELTF MELTF P08582 Melanotransferrin chr3 Not Cancer Driver No 1 hippie 106 23 6 6 0
MGST1_ENST00000396210 MGST1 P10620 Microsomal glutathione S-transferase 1 chr12 Not Cancer Driver No 1 hippie 26 0 0 0 0
MME_ENST00000492661 MME P08473 Neprilysin chr3 Not Cancer Driver No 1 hippie 189 40 17 17 4
MMGT1 MMGT1 Q8N4V1 ER membrane protein complex subunit 5 chrX Not Cancer Driver No 3 intact, hippie, biogrid 24 17 4 4 0
MMP15 MMP15 P51511 Matrix metalloproteinase-15 chr16 Not Cancer Driver No 1 hippie 78 205 23 23 0
MRPL23 MRPL23 Q16540 39S ribosomal protein L23, mitochondrial chr11 Not Cancer Driver No 1 hippie 29 68 12 12 0
MRPL37_ENST00000360840 MRPL37 Q9BZE1 39S ribosomal protein L37, mitochondrial chr1 Not Cancer Driver No 1 hippie 44 36 5 5 0
MRPL48 MRPL48 Q96GC5 39S ribosomal protein L48, mitochondrial chr11 Not Cancer Driver No 1 hippie 16 15 1 1 0
MSLN MSLN Q13421 Mesothelin chr16 Not Cancer Driver No 1 hippie 88 126 22 22 0
MYOF MYOF Q9NZM1 Myoferlin chr10 Not Cancer Driver No 1 hippie 269 401 55 55 0
NASP NASP P49321 Nuclear autoantigenic sperm protein chr1 Not Cancer Driver No 1 hippie 95 615 81 81 0
NDFIP1 NDFIP1 Q9BT67 NEDD4 family-interacting protein 1 chr5 Not Cancer Driver No 1 hippie, biogrid 22 44 4 4 0
NDUFA9 NDUFA9 Q16795 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial chr12 Not Cancer Driver No 1 hippie 57 8 0 0 2
NDUFB5 NDUFB5 O43674 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial chr3 Not Cancer Driver No 1 hippie 28 9 1 1 0
NDUFB9 NDUFB9 Q9Y6M9 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 chr8 Not Cancer Driver No 1 hippie 23 34 5 5 1
NDUFS1_ENST00000449699 NDUFS1 P28331 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial chr2 Not Cancer Driver No 1 hippie 81 40 3 3 2
NDUFS2 NDUFS2 O75306 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial chr1 Not Cancer Driver No 1 hippie 58 49 5 5 4
NDUFV1 NDUFV1 P49821 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial chr11 Not Cancer Driver No 1 hippie 66 57 9 9 3
NNT_ENST00000344920 NNT Q13423 NAD(P) transhydrogenase, mitochondrial chr5 Not Cancer Driver No 1 hippie 129 47 6 6 11
NOMO1 NOMO1 Q15155 Nodal modulator 1 chr16 Not Cancer Driver No 1 hippie, biogrid 130 128 23 23 0
NOP56 NOP56 O00567 Nucleolar protein 56 chr20 Not Cancer Driver No 1 hippie, biogrid 83 191 34 34 0
NPC1 NPC1 O15118 NPC intracellular cholesterol transporter 1 chr18 Not Cancer Driver No 1 hippie 155 24 0 0 150
NPEPPS NPEPPS P55786 Puromycin-sensitive aminopeptidase chr17 Compendium Yes 1 hippie 102 45 5 5 0
NSDHL NSDHL Q15738 Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating chrX Not Cancer Driver No 1 hippie 60 39 6 6 3
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
NUP210 NUP210 Q8TEM1 Nuclear pore membrane glycoprotein 210 chr3 Not Cancer Driver No 1 hippie 262 156 19 19 0
OGDH OGDH Q02218 2-oxoglutarate dehydrogenase complex component E1 chr7 Not Cancer Driver No 1 hippie 150 106 19 19 0
OGDHL OGDHL Q9ULD0 2-oxoglutarate dehydrogenase-like, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 262 128 38 38 0
OMA1 OMA1 Q96E52 Metalloendopeptidase OMA1, mitochondrial chr1 Not Cancer Driver No 1 hippie 52 34 4 4 0
OR4N2_ENST00000557677 OR4N2 Q8NGD1 Olfactory receptor 4N2 chr14 Not Cancer Driver No 1 hippie, biogrid 199 0 0 0 0
OTULINL OTULINL Q9NUU6 Inactive ubiquitin thioesterase OTULINL chr5 Not Cancer Driver No 1 hippie 59 21 0 0 0
OXA1L_ENST00000604262 OXA1L Q15070 Mitochondrial inner membrane protein OXA1L chr14 Not Cancer Driver No 1 hippie 36 81 9 9 0
P2RX4_ENST00000337233 P2RX4 Q99571 P2X purinoceptor 4 chr12 Not Cancer Driver No 2 hippie, biogrid 36 0 0 0 0
P2RY6_ENST00000540342 P2RY6 Q15077 P2Y purinoceptor 6 chr11 Not Cancer Driver No 1 intact, hippie 50 10 5 5 0
P4HB P4HB P07237 Protein disulfide-isomerase chr17 Not Cancer Driver No 1 hippie 61 79 15 15 1
PAICS_ENST00000512576 PAICS P22234 Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase chr4 Not Cancer Driver No 1 hippie 23 35 3 3 0
PCK2 PCK2 Q16822 Phosphoenolpyruvate carboxykinase [GTP], mitochondrial chr14 Not Cancer Driver No 1 hippie 91 139 13 13 0
PDE2A PDE2A O00408 cGMP-dependent 3',5'-cyclic phosphodiesterase chr11 Not Cancer Driver No 1 hippie 137 99 7 7 0
PDIA4 PDIA4 P13667 Protein disulfide-isomerase A4 chr7 Not Cancer Driver No 1 hippie, biogrid 81 147 22 22 0
PGAM1 PGAM1 P18669 Phosphoglycerate mutase 1 chr10 Not Cancer Driver No 1 hippie 20 70 5 5 0
PGM1_ENST00000371084 PGM1 P36871 Phosphoglucomutase-1 chr1 Not Cancer Driver No 1 hippie 62 31 3 3 13
PIGK PIGK Q92643 GPI-anchor transamidase chr1 Not Cancer Driver No 1 hippie 54 37 9 9 5
PKM_ENST00000335181 PKM P14618 Pyruvate kinase PKM chr15 Not Cancer Driver No 1 hippie 78 58 13 13 0
PLD3_ENST00000409735 PLD3 Q8IV08 5'-3' exonuclease PLD3 chr19 Not Cancer Driver No 1 biogrid 70 62 7 7 0
PLD4_ENST00000392593 PLD4 Q96BZ4 5'-3' exonuclease PLD4 chr14 Not Cancer Driver No 1 biogrid 46 76 10 10 0
PLD6 PLD6 Q8N2A8 Mitochondrial cardiolipin hydrolase chr17 Not Cancer Driver No 1 biogrid 27 24 6 6 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PLGRKT PLGRKT Q9HBL7 Plasminogen receptor (KT) chr9 Not Cancer Driver No 1 intact, hippie 17 0 0 0 0
PLOD1 PLOD1 Q02809 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 chr1 Not Cancer Driver No 1 hippie 86 12 0 0 5
PLOD2_ENST00000360060 PLOD2 O00469 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 chr3 Not Cancer Driver No 1 hippie 109 17 3 3 4
PON2 PON2 Q15165 Serum paraoxonase/arylesterase 2 chr7 Not Cancer Driver No 1 hippie, biogrid 46 13 3 3 0
POR POR P16435 NADPH--cytochrome P450 reductase chr7 Not Cancer Driver No 1 hippie 62 93 4 4 9
POTEF POTEF A5A3E0 POTE ankyrin domain family member F chr2 Not Cancer Driver No 1 hippie, biogrid 269 453 93 93 0
PPP1R12A_ENST00000261207 PPP1R12A O14974 Protein phosphatase 1 regulatory subunit 12A chr12 Not Cancer Driver No 1 hippie 107 821 89 89 0
PRDX3 PRDX3 P30048 Thioredoxin-dependent peroxide reductase, mitochondrial chr10 Not Cancer Driver No 1 hippie 23 23 3 3 0
PRDX6 PRDX6 P30041 Peroxiredoxin-6 chr1 Not Cancer Driver No 1 hippie 46 13 4 4 0
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 Not Cancer Driver No 1 hippie 538 421 61 61 2
PRPF6 PRPF6 O94906 Pre-mRNA-processing factor 6 chr20 Not Cancer Driver No 1 hippie 140 379 62 62 1
PRPF8 PRPF8 Q6P2Q9 Pre-mRNA-processing-splicing factor 8 chr17 Not Cancer Driver No 1 hippie 255 225 26 26 8
PSEN1 PSEN1 P49768 Presenilin-1 chr14 Not Cancer Driver No 1 intact, hippie 61 134 21 21 96
PSMC5 PSMC5 P62195 26S proteasome regulatory subunit 8 chr17 Not Cancer Driver No 1 hippie 52 64 6 6 0
PSMD1 PSMD1 Q99460 26S proteasome non-ATPase regulatory subunit 1 chr2 Not Cancer Driver No 1 hippie 110 201 19 19 0
PTGES2 PTGES2 Q9H7Z7 Prostaglandin E synthase 2 chr9 Not Cancer Driver No 1 hippie 30 30 1 1 0
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 Not Cancer Driver No 1 hippie, biogrid 49 140 25 25 0
PTPRO PTPRO Q16827 Receptor-type tyrosine-protein phosphatase O chr12 Not Cancer Driver No 1 hippie 204 137 34 34 0
PTRH2_ENST00000470557 PTRH2 Q9Y3E5 Peptidyl-tRNA hydrolase 2, mitochondrial chr17 Not Cancer Driver No 1 hippie 14 19 2 2 1
PYGB PYGB P11216 Glycogen phosphorylase, brain form chr20 Not Cancer Driver No 1 hippie 118 29 5 5 0
PYGL PYGL P06737 Glycogen phosphorylase, liver form chr14 Not Cancer Driver No 1 hippie 98 23 2 2 2
RAB14 RAB14 P61106 Ras-related protein Rab-14 chr9 Not Cancer Driver No 1 hippie 20 41 4 4 0
RAB2A RAB2A P61019 Ras-related protein Rab-2A chr8 Not Cancer Driver No 1 hippie 22 58 4 4 0
RAB5A RAB5A P20339 Ras-related protein Rab-5A chr3 Not Cancer Driver No 1 hippie 32 65 15 15 0
RAB7A RAB7A P51149 Ras-related protein Rab-7a chr3 Not Cancer Driver No 2 hippie, biogrid 27 11 0 0 4
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 Census, Compendium Yes 1 hippie 66 2 1 1 6
RAC2 RAC2 P15153 Ras-related C3 botulinum toxin substrate 2 chr22 Not Cancer Driver No 1 hippie 31 0 0 0 2
RAC3 RAC3 P60763 Ras-related C3 botulinum toxin substrate 3 chr17 Not Cancer Driver No 1 hippie 24 0 0 0 4
RALA RALA P11233 Ras-related protein Ral-A chr7 Not Cancer Driver No 1 hippie 34 34 3 3 5
RALB RALB P11234 Ras-related protein Ral-B chr2 Not Cancer Driver No 1 hippie 36 35 5 5 0
RANBP1_ENST00000331821 RANBP1 P43487 Ran-specific GTPase-activating protein chr22 Not Cancer Driver No 1 hippie 19 137 16 16 0
RANBP2 RANBP2 P49792 E3 SUMO-protein ligase RanBP2 chr2 Census, Compendium Yes 1 hippie 427 1387 177 177 3
RANGAP1_ENST00000356244 RANGAP1 P46060 Ran GTPase-activating protein 1 chr22 Not Cancer Driver No 1 hippie 65 159 17 17 0
RB1CC1 RB1CC1 Q8TDY2 RB1-inducible coiled-coil protein 1 chr8 Not Cancer Driver No 1 hippie 202 578 75 75 0
RER1 RER1 O15258 Protein RER1 chr1 Not Cancer Driver No 1 hippie 18 15 3 3 0
RET RET P07949 Proto-oncogene tyrosine-protein kinase receptor Ret chr10 Census, Compendium Yes 1 intact 208 105 12 12 139
RHOA RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 99 46 13 13 2
RHOC_ENST00000369642 RHOC P08134 Rho-related GTP-binding protein RhoC chr1 Not Cancer Driver No 1 hippie 30 53 7 7 0
RHOD RHOD O00212 Rho-related GTP-binding protein RhoD chr11 Not Cancer Driver No 1 hippie 20 10 0 0 0
RHOF RHOF Q9HBH0 Rho-related GTP-binding protein RhoF chr12 Not Cancer Driver No 1 hippie 18 10 0 0 0
RHOG_ENST00000396978 RHOG P84095 Rho-related GTP-binding protein RhoG chr11 Not Cancer Driver No 1 hippie 26 22 5 5 0
RHOH_ENST00000617441 RHOH Q15669 Rho-related GTP-binding protein RhoH chr4 Census Yes 1 hippie 41 12 3 3 0
RHOJ RHOJ Q9H4E5 Rho-related GTP-binding protein RhoJ chr14 Not Cancer Driver No 1 hippie 39 0 0 0 0
RHOT2 RHOT2 Q8IXI1 Mitochondrial Rho GTPase 2 chr16 Not Cancer Driver No 1 hippie, biogrid 52 79 5 5 0
RMDN3 RMDN3 Q96TC7 Regulator of microtubule dynamics protein 3 chr15 Not Cancer Driver No 1 hippie, biogrid 45 196 17 17 0
RND1 RND1 Q92730 Rho-related GTP-binding protein Rho6 chr12 Not Cancer Driver No 1 hippie 45 9 1 1 0
RND2 RND2 P52198 Rho-related GTP-binding protein RhoN chr17 Not Cancer Driver No 1 hippie 19 54 4 4 0
RND3_ENST00000263895 RND3 P61587 Rho-related GTP-binding protein RhoE chr2 Not Cancer Driver No 1 hippie 36 70 10 10 0
RPN1 RPN1 P04843 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 chr3 Census Yes 1 hippie 50 69 3 3 0
RPN2 RPN2 P04844 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 chr20 Not Cancer Driver No 1 hippie 53 26 4 4 0
RSL1D1 RSL1D1 O76021 Ribosomal L1 domain-containing protein 1 chr16 Not Cancer Driver No 1 hippie 61 275 33 33 0
RTN4 RTN4 Q9NQC3 Reticulon-4 chr2 Not Cancer Driver No 1 hippie 121 866 82 82 0
S100A11 S100A11 P31949 Protein S100-A11 chr1 Not Cancer Driver No 1 hippie 13 14 2 2 0
SCARB2 SCARB2 Q14108 Lysosome membrane protein 2 chr4 Not Cancer Driver No 1 hippie 61 13 3 3 1
SCFD1 SCFD1 Q8WVM8 Sec1 family domain-containing protein 1 chr14 Not Cancer Driver No 1 hippie 66 117 12 12 0
SCGB1C1 SCGB1C1 Q8TD33 Secretoglobin family 1C member 1 chr11 Not Cancer Driver No 1 hippie, biogrid 32 0 0 0 0
SCGB1D1 SCGB1D1 O95968 Secretoglobin family 1D member 1 chr11 Not Cancer Driver No 1 hippie, biogrid 22 0 0 0 0
SDHA SDHA P31040 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial chr5 Census Yes 1 hippie 115 71 13 13 7
SDHB SDHB P21912 Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial chr1 Census Yes 1 hippie 37 17 3 3 23
SEC11A_ENST00000268220 SEC11A P67812 Signal peptidase complex catalytic subunit SEC11A chr15 Not Cancer Driver No 1 hippie 20 0 0 0 0
SEC61B SEC61B P60468 Protein transport protein Sec61 subunit beta chr9 Not Cancer Driver No 1 hippie, biogrid 11 60 7 7 0
SEC63 SEC63 Q9UGP8 Translocation protein SEC63 homolog chr6 Not Cancer Driver No 1 hippie, biogrid 98 266 37 37 0
SF3A1 SF3A1 Q15459 Splicing factor 3A subunit 1 chr22 Not Cancer Driver No 1 hippie 82 631 67 67 0
SF3B1 SF3B1 O75533 Splicing factor 3B subunit 1 chr2 Census, Compendium Yes 1 hippie 244 477 80 80 0
SFXN1 SFXN1 Q9H9B4 Sideroflexin-1 chr5 Not Cancer Driver No 1 hippie 31 29 1 1 0
SFXN3_ENST00000393459 SFXN3 Q9BWM7 Sideroflexin-3 chr10 Not Cancer Driver No 1 hippie 39 0 0 0 0
SLC12A3_ENST00000563236 SLC12A3 P55017 Solute carrier family 12 member 3 chr16 Not Cancer Driver No 1 hippie 146 124 16 16 117
SLC25A11 SLC25A11 Q02978 Mitochondrial 2-oxoglutarate/malate carrier protein chr17 Not Cancer Driver No 1 hippie 37 16 1 1 3
SLC25A12 SLC25A12 O75746 Calcium-binding mitochondrial carrier protein Aralar1 chr2 Not Cancer Driver No 1 hippie 110 21 7 7 2
SLC25A13_ENST00000265631 SLC25A13 Q9UJS0 Calcium-binding mitochondrial carrier protein Aralar2 chr7 Not Cancer Driver No 1 hippie 111 23 2 2 1
SLC25A24 SLC25A24 Q6NUK1 Calcium-binding mitochondrial carrier protein SCaMC-1 chr1 Not Cancer Driver No 1 hippie 40 21 2 2 2
SLC25A4 SLC25A4 P12235 ADP/ATP translocase 1 chr4 Not Cancer Driver No 1 hippie 24 0 0 0 9
SLC25A46 SLC25A46 Q96AG3 Mitochondrial outer membrane protein SLC25A46 chr5 Not Cancer Driver No 1 hippie, biogrid 37 96 2 2 4
SLC25A5 SLC25A5 P05141 ADP/ATP translocase 2 chrX Not Cancer Driver No 1 hippie 41 0 0 0 0
SLC25A6 SLC25A6 P12236 ADP/ATP translocase 3 chrX Not Cancer Driver No 1 hippie 41 0 0 0 0
SLC4A7_ENST00000295736 SLC4A7 Q9Y6M7 Sodium bicarbonate cotransporter 3 chr3 Not Cancer Driver No 1 hippie 165 406 57 57 0
SMC3 SMC3 Q9UQE7 Structural maintenance of chromosomes protein 3 chr10 Not Cancer Driver No 1 hippie 149 605 70 70 0
SNAP23 SNAP23 O00161 Synaptosomal-associated protein 23 chr15 Not Cancer Driver No 1 hippie 18 179 16 16 0
SNIP1 SNIP1 Q8TAD8 Smad nuclear-interacting protein 1 chr1 Not Cancer Driver No 1 biogrid 58 285 40 40 1
SOAT1 SOAT1 P35610 Sterol O-acyltransferase 1 chr1 Not Cancer Driver No 1 hippie 73 49 4 4 0
SPCS1 SPCS1 Q9Y6A9 Signal peptidase complex subunit 1 chr3 Not Cancer Driver No 1 hippie 18 81 9 9 0
SPCS2 SPCS2 Q15005 Signal peptidase complex subunit 2 chr11 Not Cancer Driver No 1 hippie 17 0 0 0 0
SPPL3 SPPL3 Q8TCT6 Signal peptide peptidase-like 3 chr12 Not Cancer Driver No 1 hippie, biogrid 45 23 0 0 0
ST14 ST14 Q9Y5Y6 Suppressor of tumorigenicity 14 protein chr11 Not Cancer Driver No 1 hippie, biogrid 106 47 5 5 1
ST7 ST7 Q9NRC1 Suppressor of tumorigenicity 7 protein chr7 Not Cancer Driver No 1 hippie 62 64 5 5 0
STOM STOM P27105 Stomatin chr9 Not Cancer Driver No 1 hippie 23 44 3 3 0
STOML2 STOML2 Q9UJZ1 Stomatin-like protein 2, mitochondrial chr9 Not Cancer Driver No 1 hippie 40 117 9 9 0
STT3A_ENST00000529196 STT3A P46977 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A chr11 Not Cancer Driver No 1 hippie 82 27 2 2 1
STT3B STT3B Q8TCJ2 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B chr3 Not Cancer Driver No 1 hippie 60 136 9 9 0
SUB1_ENST00000515355 SUB1 P53999 Activated RNA polymerase II transcriptional coactivator p15 chr5 Not Cancer Driver No 1 hippie 13 108 6 6 0
SUPT5H SUPT5H O00267 Transcription elongation factor SPT5 chr19 Not Cancer Driver No 1 hippie 165 572 87 87 0
SYNE3 SYNE3 Q6ZMZ3 Nesprin-3 chr14 Not Cancer Driver No 1 hippie, biogrid 143 236 42 42 0
TAGLN2_ENST00000368097 TAGLN2 P37802 Transgelin-2 chr1 Not Cancer Driver No 1 hippie 28 83 12 12 0
TCIRG1 TCIRG1 Q13488 V-type proton ATPase 116 kDa subunit a 3 chr11 Compendium Yes 1 hippie 68 102 6 6 5
TCTN1_ENST00000551590 TCTN1 Q2MV58 Tectonic-1 chr12 Not Cancer Driver No 1 intact, hippie 63 47 6 6 0
TCTN2 TCTN2 Q96GX1 Tectonic-2 chr12 Not Cancer Driver No 1 intact, hippie 75 23 2 2 0
TCTN3 TCTN3 Q6NUS6 Tectonic-3 chr10 Not Cancer Driver No 1 intact, hippie 45 71 8 8 1
TFCP2 TFCP2 Q12800 Alpha-globin transcription factor CP2 chr12 Not Cancer Driver No 1 hippie 68 169 23 23 0
TFRC_ENST00000392396 TFRC P02786 Transferrin receptor protein 1 chr3 Census Yes 1 hippie, biogrid 89 80 6 6 1
TIMM44 TIMM44 O43615 Mitochondrial import inner membrane translocase subunit TIM44 chr19 Not Cancer Driver No 1 hippie 56 175 22 22 0
TKT_ENST00000462138 TKT P29401 Transketolase chr3 Not Cancer Driver No 1 hippie 66 86 7 7 1
TLN1 TLN1 Q9Y490 Talin-1 chr9 Not Cancer Driver No 1 hippie 278 1109 126 126 0
TMBIM4_ENST00000358230 TMBIM4 Q9HC24 Protein lifeguard 4 chr12 Not Cancer Driver No 1 hippie 36 3 0 0 0
TMED10 TMED10 P49755 Transmembrane emp24 domain-containing protein 10 chr14 Not Cancer Driver No 1 hippie, biogrid 24 15 3 3 0
TMED2 TMED2 Q15363 Transmembrane emp24 domain-containing protein 2 chr12 Not Cancer Driver No 1 hippie, biogrid 24 25 4 4 0
TMED4 TMED4 Q7Z7H5 Transmembrane emp24 domain-containing protein 4 chr7 Not Cancer Driver No 1 hippie 20 34 2 2 0
TMED5 TMED5 Q9Y3A6 Transmembrane emp24 domain-containing protein 5 chr1 Not Cancer Driver No 1 hippie, biogrid 23 1 0 0 0
TMED9 TMED9 Q9BVK6 Transmembrane emp24 domain-containing protein 9 chr5 Not Cancer Driver No 1 hippie, biogrid 16 22 2 2 0
TMEM106B TMEM106B Q9NUM4 Transmembrane protein 106B chr7 Not Cancer Driver No 1 hippie 31 56 4 4 1
TMEM120B TMEM120B A0PK00 Transmembrane protein 120B chr12 Not Cancer Driver No 1 hippie, biogrid 37 6 1 1 0
TMEM17 TMEM17 Q86X19 Transmembrane protein 17 chr2 Not Cancer Driver No 1 intact, hippie 22 14 2 2 0
TMEM216 TMEM216 Q9P0N5 Transmembrane protein 216 chr11 Not Cancer Driver No 1 intact, hippie 11 0 0 0 7
TMEM237 TMEM237 Q96Q45 Transmembrane protein 237 chr2 Not Cancer Driver No 1 intact, hippie 47 177 19 19 0
TMEM43 TMEM43 Q9BTV4 Transmembrane protein 43 chr3 Not Cancer Driver No 1 hippie 47 57 9 9 3
TMEM67 TMEM67 Q5HYA8 Meckelin chr8 Not Cancer Driver No 1 intact, hippie 120 11 0 0 37
TMPRSS11B TMPRSS11B Q86T26 Transmembrane protease serine 11B chr4 Not Cancer Driver No 1 hippie, biogrid 95 5 0 0 0
TMPRSS13_ENST00000445164 TMPRSS13 Q9BYE2 Transmembrane protease serine 13 chr11 Not Cancer Driver No 1 hippie, biogrid 122 199 75 75 0
TMPRSS2_ENST00000458356 TMPRSS2 O15393 Transmembrane protease serine 2 chr21 Census Yes 1 hippie, biogrid 66 25 5 5 0
TMTC3 TMTC3 Q6ZXV5 Protein O-mannosyl-transferase TMTC3 chr12 Not Cancer Driver No 1 hippie 122 84 7 7 2
TNIK TNIK Q9UKE5 TRAF2 and NCK-interacting protein kinase chr3 Not Cancer Driver No 1 intact, hippie 254 781 156 156 0
TOMM70 TOMM70 O94826 Mitochondrial import receptor subunit TOM70 chr3 Not Cancer Driver No 1 hippie 59 140 8 8 0
TOR1AIP1_ENST00000606911 TOR1AIP1 Q5JTV8 Torsin-1A-interacting protein 1 chr1 Not Cancer Driver No 1 hippie 71 401 44 44 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2891 282 1466 1466 83
TPI1_ENST00000396705 TPI1 P60174 Triosephosphate isomerase chr12 Not Cancer Driver No 1 hippie 40 15 2 2 7
TPR TPR P12270 Nucleoprotein TPR chr1 Census Yes 1 hippie 311 1990 266 266 0
TRDN TRDN Q13061 Triadin chr6 Not Cancer Driver No 1 hippie, biogrid 129 639 102 102 1
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 87 430 41 41 0
TSC22D1 TSC22D1 Q15714 TSC22 domain family protein 1 chr13 Not Cancer Driver No 1 intact, hippie, biogrid 110 1023 98 98 0
UBAC2 UBAC2 Q8NBM4 Ubiquitin-associated domain-containing protein 2 chr13 Not Cancer Driver No 1 hippie 33 57 9 9 0
UGGT1 UGGT1 Q9NYU2 UDP-glucose:glycoprotein glucosyltransferase 1 chr2 Not Cancer Driver No 1 hippie 169 161 20 20 0
UNC93B1 UNC93B1 Q9H1C4 Protein unc-93 homolog B1 chr11 Not Cancer Driver No 1 intact, hippie 57 127 5 5 0
UQCRC1 UQCRC1 P31930 Cytochrome b-c1 complex subunit 1, mitochondrial chr3 Not Cancer Driver No 1 hippie 57 55 6 6 2
UQCRC2 UQCRC2 P22695 Cytochrome b-c1 complex subunit 2, mitochondrial chr16 Not Cancer Driver No 1 hippie 53 48 13 13 1
UQCRFS1 UQCRFS1 P47985 Cytochrome b-c1 complex subunit Rieske, mitochondrial chr19 Not Cancer Driver No 1 hippie 43 47 4 4 1
VAPA_ENST00000400000 VAPA Q9P0L0 Vesicle-associated membrane protein-associated protein A chr18 Not Cancer Driver No 1 hippie, biogrid 24 184 14 14 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 Not Cancer Driver No 1 hippie 88 186 16 16 16
VDAC1_ENST00000395047 VDAC1 P21796 Voltage-dependent anion-selective channel protein 1 chr5 Not Cancer Driver No 1 hippie 38 36 4 4 0
VDAC2_ENST00000543351 VDAC2 P45880 Voltage-dependent anion-selective channel protein 2 chr10 Not Cancer Driver No 1 intact, hippie 35 9 1 1 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
VPS35 VPS35 Q96QK1 Vacuolar protein sorting-associated protein 35 chr16 Not Cancer Driver No 1 hippie 68 99 9 9 1
VSTM1 VSTM1 Q6UX27 V-set and transmembrane domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie, biogrid 72 126 40 40 0
XPO1_ENST00000406957 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie 140 33 9 9 0
XPO5 XPO5 Q9HAV4 Exportin-5 chr6 Not Cancer Driver No 1 hippie 112 64 7 7 0
YME1L1 YME1L1 Q96TA2 ATP-dependent zinc metalloprotease YME1L1 chr10 Not Cancer Driver No 1 hippie 112 136 14 14 1
ZACN ZACN Q401N2 Zinc-activated ligand-gated ion channel chr17 Not Cancer Driver No 3 hippie, biogrid 46 48 6 6 0
ZMPSTE24 ZMPSTE24 O75844 CAAX prenyl protease 1 homolog chr1 Not Cancer Driver No 1 hippie 67 23 0 0 3