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ELK4 ,ELK4 ,P28324
  • Uniprot Accession= P28324
  • Ensembl Transcript= ENST00000357992.8
  • Uniprot Name= ELK4
  • Name= ETS domain-containing protein Elk-4
  • Chromosome= chr1
  • Driver status= Census
  • Number of Interaction partner in intact: 66
  • Number of Interaction partner in biogrid: 0
  • Number of Interaction partner in hippie: 64
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACADVL_ENST00000356839 ACADVL P49748 Very long-chain specific acyl-CoA dehydrogenase, mitochondrial chr17 Not Cancer Driver No 1 intact, hippie 50 100 5 5 37
ACAP2 ACAP2 Q15057 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 chr3 Not Cancer Driver No 1 intact, hippie 97 287 40 40 0
ACTBL2 ACTBL2 Q562R1 Beta-actin-like protein 2 chr5 Not Cancer Driver No 1 intact, hippie 73 29 5 5 0
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 1 intact, hippie 112 43 5 5 5
ACTG1_ENST00000575087 ACTG1 P63261 Actin, cytoplasmic 2 chr17 Not Cancer Driver No 1 intact, hippie 73 42 10 10 16
AKAP12 AKAP12 Q02952 A-kinase anchor protein 12 chr6 Not Cancer Driver No 1 intact, hippie 215 1770 214 214 0
ANKRA2 ANKRA2 Q9H9E1 Ankyrin repeat family A protein 2 chr5 Not Cancer Driver No 1 intact 31 97 11 11 0
BCLAF1 BCLAF1 Q9NYF8 Bcl-2-associated transcription factor 1 chr6 Census, Compendium Yes 1 hippie 421 899 408 408 0
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 224 1458 174 174 35
CAPZA1 CAPZA1 P52907 F-actin-capping protein subunit alpha-1 chr1 Not Cancer Driver No 1 intact, hippie 40 41 2 2 0
CAPZB_ENST00000375142 CAPZB P47756 F-actin-capping protein subunit beta chr1 Not Cancer Driver No 1 intact, hippie 33 66 3 3 0
CCL2 CCL2 P13500 C-C motif chemokine 2 chr17 Not Cancer Driver No 1 intact 20 15 5 5 0
CLNS1A_ENST00000528364 CLNS1A P54105 Methylosome subunit pICln chr11 Not Cancer Driver No 1 hippie 19 170 13 13 0
CORO1C_ENST00000541050 CORO1C Q9ULV4 Coronin-1C chr12 Not Cancer Driver No 1 intact, hippie 61 84 13 13 0
CUL4A CUL4A Q13619 Cullin-4A chr13 Not Cancer Driver No 1 intact, hippie 64 102 2 2 0
DOK4_ENST00000340099 DOK4 Q8TEW6 Docking protein 4 chr16 Not Cancer Driver No 1 hippie 42 45 3 3 0
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
ELK4 ELK4 P28324 ETS domain-containing protein Elk-4 chr1 Census Yes 1 hippie 46 239 26 26 0
ERH ERH P84090 Enhancer of rudimentary homolog chr14 Not Cancer Driver No 1 intact, hippie 7 11 0 0 0
FOS FOS P01100 Protein c-Fos chr14 Not Cancer Driver No 1 hippie 45 245 33 33 0
GRPEL1 GRPEL1 Q9HAV7 GrpE protein homolog 1, mitochondrial chr4 Not Cancer Driver No 1 hippie 22 88 7 7 0
H2AFJ H2AJ Q9BTM1 Histone H2A.J chr12 Not Cancer Driver No 1 intact 17 54 9 9 0
H2BFS H2BC12L P57053 Histone H2B type F-S chr21 Not Cancer Driver No 1 intact 1 86 1 1 0
H3F3C H3-5 Q6NXT2 Histone H3.3C chr12 Not Cancer Driver No 1 intact 38 50 10 10 0
HIST1H2AC H2AC6 Q93077 Histone H2A type 1-C chr6 Not Cancer Driver No 1 intact 35 58 20 20 0
HIST1H2AD H2AC7 P20671 Histone H2A type 1-D chr6 Not Cancer Driver No 1 intact 22 63 14 14 0
HIST1H2AH H2AC12 Q96KK5 Histone H2A type 1-H chr6 Not Cancer Driver No 1 intact 31 55 12 12 0
HIST1H2AJ H2AC14 Q99878 Histone H2A type 1-J chr6 Not Cancer Driver No 1 intact 28 56 11 11 0
HIST1H2BH H2BC9 Q93079 Histone H2B type 1-H chr6 Not Cancer Driver No 1 intact 42 79 20 20 0
HIST1H2BK H2BC12 O60814 Histone H2B type 1-K chr6 Not Cancer Driver No 1 intact 42 78 29 29 0
HIST1H2BL H2BC13 Q99880 Histone H2B type 1-L chr6 Not Cancer Driver No 1 intact 34 74 20 20 0
HIST1H2BM H2BC14 Q99879 Histone H2B type 1-M chr6 Not Cancer Driver No 1 intact 37 75 23 23 0
HIST1H2BN H2BC15 Q99877 Histone H2B type 1-N chr6 Not Cancer Driver No 1 intact 21 82 11 11 0
HIST1H4A H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 15 31 5 5 0
HIST1H4B H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 29 31 6 6 0
HIST1H4C H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 29 31 7 7 0
HIST1H4D H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 32 31 8 8 0
HIST1H4E H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 45 31 14 14 0
HIST1H4F H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 30 31 7 7 0
HIST1H4H H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 22 31 9 9 0
HIST1H4I H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 33 31 10 10 0
HIST1H4J H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 26 31 9 9 0
HIST1H4K H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 44 31 13 13 0
HIST1H4L H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 25 31 14 14 0
HIST2H2AC H2AC20 Q16777 Histone H2A type 2-C chr1 Not Cancer Driver No 1 intact 39 56 18 18 0
HIST2H2BF_ENST00000369167 H2BC18 Q5QNW6 Histone H2B type 2-F chr1 Not Cancer Driver No 1 intact 33 77 23 23 0
HIST2H3C H3C13 Q71DI3 Histone H3.2 chr1 Not Cancer Driver No 1 intact 1 51 0 0 0
HIST2H3D H3C13 Q71DI3 Histone H3.2 chr1 Not Cancer Driver No 1 intact 29 51 11 11 0
HIST3H2A H2AW Q7L7L0 Histone H2A type 3 chr1 Not Cancer Driver No 1 intact 21 61 10 10 0
HIST3H3 H3-4 Q16695 Histone H3.1t chr1 Not Cancer Driver No 1 intact 37 51 10 10 0
HIST4H4 H4-16 P62805 Histone H4 chr12 Not Cancer Driver No 1 intact 21 31 7 7 0
HNRNPL HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 89 283 29 29 0
HNRNPUL1 HNRNPUL1 Q9BUJ2 Heterogeneous nuclear ribonucleoprotein U-like protein 1 chr19 Not Cancer Driver No 1 hippie 100 535 49 49 0
HSPB1 HSPB1 P04792 Heat shock protein beta-1 chr7 Not Cancer Driver No 1 intact, hippie 10 118 8 8 20
ID1 ID1 P41134 DNA-binding protein inhibitor ID-1 chr20 Not Cancer Driver No 1 hippie 20 17 6 6 0
ID2_ENST00000396290 ID2 Q02363 DNA-binding protein inhibitor ID-2 chr2 Not Cancer Driver No 1 hippie 14 52 7 7 0
ID3 ID3 Q02535 DNA-binding protein inhibitor ID-3 chr1 Census, Compendium Yes 1 hippie 14 34 4 4 0
IL18 IL18 Q14116 Interleukin-18 chr11 Not Cancer Driver No 1 intact 19 16 3 3 0
IL23A IL23A Q9NPF7 Interleukin-23 subunit alpha chr12 Not Cancer Driver No 1 intact 15 42 3 3 0
IL36A IL36A Q9UHA7 Interleukin-36 alpha chr2 Not Cancer Driver No 1 intact 44 13 3 3 0
ITGA3 ITGA3 P26006 Integrin alpha-3 chr17 Not Cancer Driver No 1 intact, hippie 106 129 18 18 3
IVNS1ABP IVNS1ABP Q9Y6Y0 Influenza virus NS1A-binding protein chr1 Not Cancer Driver No 1 hippie 85 90 12 12 0
KIF11 KIF11 P52732 Kinesin-like protein KIF11 chr10 Not Cancer Driver No 1 intact, hippie 90 389 26 26 4
LARP1 LARP1 Q6PKG0-3 Isoform 2 of La-related protein 1 chr5 Not Cancer Driver No 1 hippie 136 726 100 100 0
LIMA1_ENST00000341247 LIMA1 Q9UHB6 LIM domain and actin-binding protein 1 chr12 Not Cancer Driver No 1 hippie 88 687 81 81 0
LUC7L3_ENST00000240304 LUC7L3 O95232 Luc7-like protein 3 chr17 Not Cancer Driver No 1 intact, hippie 59 323 47 47 0
MAPK11 MAPK11 Q15759 Mitogen-activated protein kinase 11 chr22 Not Cancer Driver No 1 hippie 23 64 2 2 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 Census, Compendium Yes 1 hippie 62 2 0 0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 Not Cancer Driver No 1 hippie 38 49 5 5 0
MAPK7 MAPK7 Q13164 Mitogen-activated protein kinase 7 chr17 Not Cancer Driver No 1 hippie 92 490 50 50 0
MAPK8_ENST00000374189 MAPK8 P45983 Mitogen-activated protein kinase 8 chr10 Not Cancer Driver No 1 hippie 64 94 9 9 0
MRPL16 MRPL16 Q9NX20 39S ribosomal protein L16, mitochondrial chr11 Not Cancer Driver No 1 intact, hippie 38 57 11 11 0
MRPL4_ENST00000307422 MRPL4 Q9BYD3 39S ribosomal protein L4, mitochondrial chr19 Not Cancer Driver No 1 intact, hippie 29 105 14 14 0
MTMR14 MTMR14 Q8NCE2 Myotubularin-related protein 14 chr3 Not Cancer Driver No 1 hippie 58 150 8 8 2
MYCBP MYCBP Q99417 c-Myc-binding protein chr1 Not Cancer Driver No 1 hippie 8 54 4 4 0
MYO1C MYO1C O00159 Unconventional myosin-Ic chr17 Not Cancer Driver No 1 intact, hippie 110 66 11 11 0
OTUD4_ENST00000447906 OTUD4 Q01804 OTU domain-containing protein 4 chr4 Not Cancer Driver No 1 hippie 148 788 120 120 0
PABPC4_ENST00000372857 PABPC4 Q13310 Polyadenylate-binding protein 4 chr1 Not Cancer Driver No 1 intact, hippie 89 253 49 49 0
PPBP PPBP P02775 Platelet basic protein chr4 Not Cancer Driver No 1 intact 30 21 8 8 0
PPM1B PPM1B O75688 Protein phosphatase 1B chr2 Not Cancer Driver No 1 hippie 65 243 31 31 0
PRMT5 PRMT5 O14744 Protein arginine N-methyltransferase 5 chr14 Not Cancer Driver No 1 intact, hippie 83 72 6 6 0
PRPF31 PRPF31 Q8WWY3 U4/U6 small nuclear ribonucleoprotein Prp31 chr19 Not Cancer Driver No 1 hippie 58 213 17 17 2
PRPS1 PRPS1 P60891 Ribose-phosphate pyrophosphokinase 1 chrX Not Cancer Driver No 1 hippie 50 0 0 0 14
PRPS2_ENST00000380668 PRPS2 P11908 Ribose-phosphate pyrophosphokinase 2 chrX Not Cancer Driver No 1 hippie 56 4 1 1 0
PRPSAP1 PRPSAP1 Q14558-2 Isoform 2 of Phosphoribosyl pyrophosphate synthase-associated protein 1 chr17 Not Cancer Driver No 1 hippie 52 50 5 5 0
PRPSAP2 PRPSAP2 O60256 Phosphoribosyl pyrophosphate synthase-associated protein 2 chr17 Not Cancer Driver No 1 hippie 54 19 3 3 0
RIOK1 RIOK1 Q9BRS2 Serine/threonine-protein kinase RIO1 chr6 Not Cancer Driver No 1 intact, hippie 69 301 37 37 0
ROCK1 ROCK1 Q13464 Rho-associated protein kinase 1 chr18 Not Cancer Driver No 1 hippie 184 780 103 103 0
SERPINH1_ENST00000358171 SERPINH1 P50454 Serpin H1 chr11 Not Cancer Driver No 1 intact, hippie 51 52 6 6 1
SIRT7 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 Not Cancer Driver No 1 hippie 48 163 15 15 0
SNRPD1 SNRPD1 P62314 Small nuclear ribonucleoprotein Sm D1 chr18 Not Cancer Driver No 1 intact, hippie 10 80 4 4 0
SNRPD2_ENST00000588301 SNRPD2 P62316 Small nuclear ribonucleoprotein Sm D2 chr19 Not Cancer Driver No 1 intact, hippie 19 67 12 12 0
SRF SRF P11831 Serum response factor chr6 Not Cancer Driver No 2 intact, hippie 44 443 42 42 0
SRSF7 SRSF7 Q16629 Serine/arginine-rich splicing factor 7 chr2 Not Cancer Driver No 1 intact, hippie 40 175 26 26 0
TCF25 TCF25 Q9BQ70 Transcription factor 25 chr16 Not Cancer Driver No 1 hippie 82 280 35 35 0
THRAP3_ENST00000469141 THRAP3 Q9Y2W1 Thyroid hormone receptor-associated protein 3 chr1 Census Yes 1 hippie 137 955 137 137 0
TNFSF4 TNFSF4 P23510 Tumor necrosis factor ligand superfamily member 4 chr1 Not Cancer Driver No 1 intact 28 1 0 0 0
TRA2B TRA2B P62995 Transformer-2 protein homolog beta chr3 Not Cancer Driver No 1 intact, hippie 59 244 54 54 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
WDR77 WDR77 Q9BQA1 Methylosome protein 50 chr1 Not Cancer Driver No 1 intact, hippie 30 41 2 2 0
YBX3 YBX3 P16989 Y-box-binding protein 3 chr12 Not Cancer Driver No 1 intact, hippie 49 359 47 47 0