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EIF4G3_ENST00000264211 ,EIF4G3 ,O43432
  • Uniprot Accession= O43432
  • Ensembl Transcript= ENST00000264211.12
  • Uniprot Name= EIF4G3
  • Name= Eukaryotic translation initiation factor 4 gamma 3
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 24
  • Number of Interaction partner in biogrid: 54
  • Number of Interaction partner in hippie: 94
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ALDH3A2_ENST00000579855 ALDH3A2 P51648 Aldehyde dehydrogenase family 3 member A2 chr17 Not Cancer Driver No 1 hippie, biogrid 47 5 2 2 26
ANGEL1 ANGEL1 Q9UNK9 Protein angel homolog 1 chr14 Not Cancer Driver No 1 hippie, biogrid 85 160 21 21 0
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 Not Cancer Driver No 1 hippie 34 103 14 14 0
BAG2 BAG2 O95816 BAG family molecular chaperone regulator 2 chr6 Not Cancer Driver No 1 hippie, biogrid 17 112 9 9 0
BCAT1_ENST00000261192 BCAT1 P54687 Branched-chain-amino-acid aminotransferase, cytosolic chr12 Not Cancer Driver No 1 hippie, biogrid 67 8 2 2 0
BMI1 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 1 intact, hippie 50 150 30 30 0
BTNL9 BTNL9 Q6UXG8 Butyrophilin-like protein 9 chr5 Not Cancer Driver No 1 hippie, biogrid 69 87 4 4 0
CAMK1 CAMK1 Q14012 Calcium/calmodulin-dependent protein kinase type 1 chr3 Not Cancer Driver No 1 hippie 40 31 1 1 0
CAMK2A_ENST00000348628 CAMK2A Q9UQM7 Calcium/calmodulin-dependent protein kinase type II subunit alpha chr5 Not Cancer Driver No 1 hippie, biogrid 83 62 10 10 7
CCT8L2 CCT8L2 Q96SF2 T-complex protein 1 subunit theta-like 2 chr22 Not Cancer Driver No 1 hippie, biogrid 216 104 46 46 0
COMTD1 COMTD1 Q86VU5 Catechol O-methyltransferase domain-containing protein 1 chr10 Not Cancer Driver No 3 intact, hippie, biogrid 11 23 0 0 0
CRYBG2_ENST00000308182 CRYBG2 Q8N1P7 Beta/gamma crystallin domain-containing protein 2 chr1 Not Cancer Driver No 1 hippie 83 1078 34 34 0
CTR9 CTR9 Q6PD62 RNA polymerase-associated protein CTR9 homolog chr11 Not Cancer Driver No 1 intact, hippie 164 385 48 48 0
DAZL_ENST00000399444 DAZL Q92904 Deleted in azoospermia-like chr3 Not Cancer Driver No 1 hippie 28 128 12 12 0
DISC1_ENST00000439617 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 Not Cancer Driver No 1 intact, hippie 132 514 82 82 0
DYRK1A_ENST00000644942 DYRK1A Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A chr21 Not Cancer Driver No 1 hippie 135 447 73 73 0
EEA1 EEA1 Q15075 Early endosome antigen 1 chr12 Not Cancer Driver No 1 intact, hippie 151 1168 126 126 0
EFNB1 EFNB1 P98172 Ephrin-B1 chrX Not Cancer Driver No 1 hippie, biogrid 46 126 14 14 19
EIF2B5 EIF2B5 Q13144 Translation initiation factor eIF-2B subunit epsilon chr3 Not Cancer Driver No 1 hippie, biogrid 76 179 16 16 29
EIF3A EIF3A Q14152 Eukaryotic translation initiation factor 3 subunit A chr10 Not Cancer Driver No 1 hippie, biogrid 181 835 130 130 0
EIF3B_ENST00000397011 EIF3B P55884 Eukaryotic translation initiation factor 3 subunit B chr7 Not Cancer Driver No 2 hippie, biogrid 89 226 4 4 0
EIF3C EIF3C Q99613 Eukaryotic translation initiation factor 3 subunit C chr16 Not Cancer Driver No 1 hippie, biogrid 15 391 12 12 0
EIF3D EIF3D O15371 Eukaryotic translation initiation factor 3 subunit D chr22 Not Cancer Driver No 1 hippie, biogrid 63 200 26 26 0
EIF3E EIF3E P60228 Eukaryotic translation initiation factor 3 subunit E chr8 Census, Compendium Yes 1 hippie, biogrid 73 27 1 1 0
EIF3F_ENST00000309828 EIF3F O00303 Eukaryotic translation initiation factor 3 subunit F chr11 Not Cancer Driver No 2 hippie, biogrid 29 125 8 8 1
EIF3G EIF3G O75821 Eukaryotic translation initiation factor 3 subunit G chr19 Not Cancer Driver No 1 hippie, biogrid 41 233 30 30 0
EIF3H EIF3H O15372 Eukaryotic translation initiation factor 3 subunit H chr8 Not Cancer Driver No 2 hippie, biogrid 37 109 12 12 0
EIF3I EIF3I Q13347 Eukaryotic translation initiation factor 3 subunit I chr1 Not Cancer Driver No 1 hippie, biogrid 47 46 6 6 0
EIF3K EIF3K Q9UBQ5 Eukaryotic translation initiation factor 3 subunit K chr19 Not Cancer Driver No 1 hippie, biogrid 25 0 0 0 0
EIF3L EIF3L Q9Y262 Eukaryotic translation initiation factor 3 subunit L chr22 Not Cancer Driver No 1 hippie, biogrid 60 41 1 1 0
EIF3M EIF3M Q7L2H7 Eukaryotic translation initiation factor 3 subunit M chr11 Not Cancer Driver No 1 hippie, biogrid 44 0 0 0 0
EIF4A1 EIF4A1 P60842 Eukaryotic initiation factor 4A-I chr17 Not Cancer Driver No 5 intact, hippie, biogrid 48 35 7 7 0
EIF4A2 EIF4A2 Q14240 Eukaryotic initiation factor 4A-II chr3 Census Yes 3 hippie, biogrid 77 27 14 14 0
EIF4EBP1 EIF4EBP1 Q13541 Eukaryotic translation initiation factor 4E-binding protein 1 chr8 Not Cancer Driver No 1 hippie, biogrid 8 118 8 8 0
EIF4EBP2 EIF4EBP2 Q13542 Eukaryotic translation initiation factor 4E-binding protein 2 chr10 Not Cancer Driver No 1 hippie, biogrid 17 118 14 14 0
EIF4ENIF1 EIF4ENIF1 Q9NRA8 Eukaryotic translation initiation factor 4E transporter chr22 Not Cancer Driver No 1 hippie, biogrid 116 899 101 101 0
EIF4E_ENST00000450253 EIF4E P06730 Eukaryotic translation initiation factor 4E chr4 Not Cancer Driver No 6 hippie, biogrid 26 54 6 6 0
EIF4G1_ENST00000346169 EIF4G1 Q04637 Eukaryotic translation initiation factor 4 gamma 1 chr3 Not Cancer Driver No 2 hippie, biogrid 229 1079 153 153 2
EIF4G2_ENST00000640650 EIF4G2 P78344 Eukaryotic translation initiation factor 4 gamma 2 chr11 Not Cancer Driver No 1 hippie, biogrid 104 382 43 43 0
EPHA1 EPHA1 P21709 Ephrin type-A receptor 1 chr7 Not Cancer Driver No 2 intact, hippie, biogrid 147 211 38 38 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 2 intact, hippie 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
EZR EZR P15311 Ezrin chr6 Census Yes 1 intact, hippie 66 295 35 35 0
GRWD1 GRWD1 Q9BQ67 Glutamate-rich WD repeat-containing protein 1 chr19 Not Cancer Driver No 1 hippie 44 187 14 14 0
HAO2_ENST00000325945 HAO2 Q9NYQ3 2-Hydroxyacid oxidase 2 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 102 12 5 5 0
HNRNPL HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 89 283 29 29 0
HSPA1L HSPA1L P34931 Heat shock 70 kDa protein 1-like chr6 Not Cancer Driver No 1 hippie, biogrid 119 141 28 28 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 intact, hippie 149 251 52 52 0
HSPB1 HSPB1 P04792 Heat shock protein beta-1 chr7 Not Cancer Driver No 1 intact, hippie 10 118 8 8 20
HTRA2 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 Compendium Yes 1 hippie 44 127 9 9 2
IFT140 IFT140 Q96RY7 Intraflagellar transport protein 140 homolog chr16 Not Cancer Driver No 1 hippie 176 161 27 27 10
IMMP1L IMMP1L Q96LU5 Mitochondrial inner membrane protease subunit 1 chr11 Not Cancer Driver No 1 hippie 20 3 0 0 0
IMMP2L_ENST00000452895 IMMP2L Q96T52 Mitochondrial inner membrane protease subunit 2 chr7 Not Cancer Driver No 1 hippie 36 29 7 7 0
KIF23 KIF23 Q02241 Kinesin-like protein KIF23 chr15 Not Cancer Driver No 1 hippie 102 559 62 62 0
KPTN KPTN Q9Y664 KICSTOR complex protein kaptin chr19 Not Cancer Driver No 3 hippie, biogrid 44 21 2 2 0
LGR4 LGR4 Q9BXB1 Leucine-rich repeat-containing G-protein coupled receptor 4 chr11 Not Cancer Driver No 1 hippie 108 16 3 3 0
LIG4 LIG4 P49917 DNA ligase 4 chr13 Not Cancer Driver No 1 hippie 134 63 10 10 2
LMBR1L LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 57 4 0 0 0
MKNK1 MKNK1 Q9BUB5 MAP kinase-interacting serine/threonine-protein kinase 1 chr1 Not Cancer Driver No 1 hippie 54 149 24 24 0
MRFAP1L1 MRFAP1L1 Q96HT8 MORF4 family-associated protein 1-like 1 chr4 Not Cancer Driver No 1 hippie, biogrid 12 59 5 5 0
MSI1 MSI1 O43347 RNA-binding protein Musashi homolog 1 chr12 Not Cancer Driver No 1 hippie, biogrid 45 133 16 16 0
NAA40 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 22 30 3 3 0
NBEAL2 NBEAL2 Q6ZNJ1 Neurobeachin-like protein 2 chr3 Not Cancer Driver No 1 intact, hippie 295 515 59 59 8
NCBP1 NCBP1 Q09161 Nuclear cap-binding protein subunit 1 chr9 Not Cancer Driver No 1 intact, hippie 88 89 8 8 0
NDN NDN Q99608 Necdin chr15 Not Cancer Driver No 1 intact, hippie 123 117 42 42 0
NFATC2IP NFATC2IP Q8NCF5 NFATC2-interacting protein chr16 Not Cancer Driver No 2 hippie, biogrid 41 330 29 29 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
OCIAD1 OCIAD1 Q9NX40 OCIA domain-containing protein 1 chr4 Not Cancer Driver No 1 hippie, biogrid 37 169 25 25 0
PABPC1 PABPC1 P11940 Polyadenylate-binding protein 1 chr8 Census, Compendium Yes 2 intact, hippie, biogrid 100 317 55 55 0
PABPC4_ENST00000372857 PABPC4 Q13310 Polyadenylate-binding protein 4 chr1 Not Cancer Driver No 1 hippie, biogrid 89 253 49 49 0
PKM_ENST00000335181 PKM P14618 Pyruvate kinase PKM chr15 Not Cancer Driver No 1 hippie 78 58 13 13 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PNKD PNKD Q8N490 Probable hydrolase PNKD chr2 Not Cancer Driver No 2 intact, hippie, biogrid 52 160 25 25 2
PSMC3_ENST00000298852 PSMC3 P17980 26S proteasome regulatory subunit 6A chr11 Not Cancer Driver No 1 hippie, biogrid 55 131 10 10 0
PUS7_ENST00000469408 PUS7 Q96PZ0 Pseudouridylate synthase 7 homolog chr7 Not Cancer Driver No 1 hippie, biogrid 73 162 17 17 1
QPRT QPRT Q15274 Nicotinate-nucleotide pyrophosphorylase [carboxylating] chr16 Not Cancer Driver No 3 intact, hippie, biogrid 29 7 1 1 0
RBFOX2_ENST00000449924 RBFOX2 O43251 RNA binding protein fox-1 homolog 2 chr22 Compendium Yes 3 intact, hippie, biogrid 44 173 22 22 0
RPS27L RPS27L Q71UM5 40S ribosomal protein S27-like chr15 Not Cancer Driver No 1 hippie, biogrid 4 22 2 2 0
RYBP RYBP Q8N488 RING1 and YY1-binding protein chr3 Not Cancer Driver No 1 hippie 37 214 37 37 0
SF3A2 SF3A2 Q15428 Splicing factor 3A subunit 2 chr19 Not Cancer Driver No 1 hippie, biogrid 30 382 21 21 0
SHARPIN SHARPIN Q9H0F6 Sharpin chr8 Not Cancer Driver No 1 hippie, biogrid 34 237 16 16 0
SHC1_ENST00000368445 SHC1 P29353 SHC-transforming protein 1 chr1 Not Cancer Driver No 1 hippie 84 397 58 58 0
SIGLECL1 SIGLECL1 Q8N7X8 SIGLEC family-like protein 1 chr19 Not Cancer Driver No 2 intact, hippie, biogrid 56 35 14 14 0
SIRT7 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 Not Cancer Driver No 1 hippie 48 163 15 15 0
TARDBP TARDBP Q13148 TAR DNA-binding protein 43 chr1 Not Cancer Driver No 1 hippie, biogrid 51 202 15 15 27
TENT5A TENT5A Q96IP4 Terminal nucleotidyltransferase 5A chr6 Not Cancer Driver No 1 intact, hippie 43 0 0 0 0
TGM1 TGM1 P22735 Protein-glutamine gamma-glutamyltransferase K chr14 Not Cancer Driver No 1 hippie, biogrid 118 230 37 37 65
TGM7 TGM7 Q96PF1 Protein-glutamine gamma-glutamyltransferase Z chr15 Not Cancer Driver No 1 hippie, biogrid 119 80 8 8 0
THRSP THRSP Q92748 Thyroid hormone-inducible hepatic protein chr11 Not Cancer Driver No 1 hippie, biogrid 28 47 7 7 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 87 430 41 41 0
USP10_ENST00000219473 USP10 Q14694 Ubiquitin carboxyl-terminal hydrolase 10 chr16 Not Cancer Driver No 1 intact, hippie, biogrid 92 425 49 49 0
VAV2 VAV2 P52735 Guanine nucleotide exchange factor VAV2 chr9 Not Cancer Driver No 1 intact, hippie 127 135 17 17 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
WDYHV1 NTAQ1 Q96HA8 Protein N-terminal glutamine amidohydrolase chr8 Not Cancer Driver No 1 intact 38 26 3 3 0
YTHDF2_ENST00000542507 YTHDF2 Q9Y5A9 YTH domain-containing family protein 2 chr1 Not Cancer Driver No 1 hippie 67 376 44 44 0