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EIF2B3 ,EIF2B3 ,Q9NR50
  • Uniprot Accession= Q9NR50
  • Ensembl Transcript= ENST00000360403.6
  • Uniprot Name= EIF2B3
  • Name= Translation initiation factor eIF-2B subunit gamma
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 48
  • Number of Interaction partner in hippie: 100
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
ABCF1 ABCF1 Q8NE71 ATP-binding cassette sub-family F member 1 chr6 Not Cancer Driver No 1 hippie 106 445 64 64 0
BCL2L14 BCL2L14 Q9BZR8 Apoptosis facilitator Bcl-2-like protein 14 chr12 Not Cancer Driver No 1 hippie 29 40 4 4 0
BTC BTC P35070 Probetacellulin chr4 Not Cancer Driver No 1 hippie, biogrid 29 12 5 5 0
BTNL9 BTNL9 Q6UXG8 Butyrophilin-like protein 9 chr5 Not Cancer Driver No 1 hippie, biogrid 69 87 4 4 0
C3orf18_ENST00000426034 C3orf18 Q9UK00 Uncharacterized protein C3orf18 chr3 Not Cancer Driver No 1 hippie, biogrid 24 111 19 19 0
CA14 CA14 Q9ULX7 Carbonic anhydrase 14 chr1 Not Cancer Driver No 3 hippie, biogrid 51 104 14 14 0
CACNG4 CACNG4 Q9UBN1 Voltage-dependent calcium channel gamma-4 subunit chr17 Not Cancer Driver No 1 hippie, biogrid 51 71 17 17 0
CD226_ENST00000582621 CD226 Q15762 CD226 antigen chr18 Not Cancer Driver No 1 hippie, biogrid 79 47 11 11 0
CD4 CD4 P01730 T-cell surface glycoprotein CD4 chr12 Not Cancer Driver No 1 hippie, biogrid 69 56 11 11 0
CD70_ENST00000245903 CD70 P32970 CD70 antigen chr19 Not Cancer Driver No 2 hippie, biogrid 33 11 2 2 0
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 Census Yes 1 hippie 31 185 20 20 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 39 23 2 2 1
CLEC2B CLEC2B Q92478 C-type lectin domain family 2 member B chr12 Not Cancer Driver No 1 hippie, biogrid 28 0 0 0 0
COMTD1 COMTD1 Q86VU5 Catechol O-methyltransferase domain-containing protein 1 chr10 Not Cancer Driver No 1 hippie, biogrid 11 23 0 0 0
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 Not Cancer Driver No 1 hippie 34 181 23 23 0
DDX1 DDX1 Q92499 ATP-dependent RNA helicase DDX1 chr2 Not Cancer Driver No 1 hippie 82 91 15 15 0
DHX9 DHX9 Q08211 ATP-dependent RNA helicase A chr1 Compendium Yes 1 hippie 182 331 42 42 0
DIMT1 DIMT1 Q9UNQ2 Probable dimethyladenosine transferase chr5 Not Cancer Driver No 1 hippie 28 37 2 2 0
DUSP3 DUSP3 P51452 Dual specificity protein phosphatase 3 chr17 Not Cancer Driver No 1 hippie 21 4 1 1 0
ECH1 ECH1 Q13011 Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial chr19 Not Cancer Driver No 3 hippie, biogrid 35 23 2 2 0
EDC4 EDC4 Q6P2E9 Enhancer of mRNA-decapping protein 4 chr16 Not Cancer Driver No 1 hippie 144 702 69 69 0
EFNB1 EFNB1 P98172 Ephrin-B1 chrX Not Cancer Driver No 1 hippie, biogrid 46 126 14 14 19
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 444 223 35 35 1
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
EIF2B1 EIF2B1 Q14232 Translation initiation factor eIF-2B subunit alpha chr12 Not Cancer Driver No 4 hippie, biogrid 33 0 0 0 2
EIF2B2 EIF2B2 P49770 Translation initiation factor eIF-2B subunit beta chr14 Not Cancer Driver No 5 hippie, biogrid 40 83 11 11 9
EIF2B3 EIF2B3 Q9NR50 Translation initiation factor eIF-2B subunit gamma chr1 Not Cancer Driver No 1 hippie 54 28 9 9 5
EIF2B4_ENST00000347454 EIF2B4 Q9UI10 Translation initiation factor eIF-2B subunit delta chr2 Not Cancer Driver No 3 hippie, biogrid 57 212 29 29 7
EIF2B5 EIF2B5 Q13144 Translation initiation factor eIF-2B subunit epsilon chr3 Not Cancer Driver No 4 hippie, biogrid 76 179 16 16 29
EIF2S1 EIF2S1 P05198 Eukaryotic translation initiation factor 2 subunit 1 chr14 Not Cancer Driver No 1 hippie 35 59 6 6 0
EIF2S2 EIF2S2 P20042 Eukaryotic translation initiation factor 2 subunit 2 chr20 Not Cancer Driver No 1 hippie 37 185 12 12 0
EIF3C EIF3C Q99613 Eukaryotic translation initiation factor 3 subunit C chr16 Not Cancer Driver No 2 hippie, biogrid 15 391 12 12 0
ENTPD2 ENTPD2 Q9Y5L3 Ectonucleoside triphosphate diphosphohydrolase 2 chr9 Not Cancer Driver No 1 hippie, biogrid 36 32 0 0 0
EPHA1 EPHA1 P21709 Ephrin type-A receptor 1 chr7 Not Cancer Driver No 2 hippie, biogrid 147 211 38 38 0
EXD2 EXD2 Q9NVH0 Exonuclease 3'-5' domain-containing protein 2 chr14 Not Cancer Driver No 1 hippie, biogrid 58 176 15 15 0
FBXO32 FBXO32 Q969P5 F-box only protein 32 chr8 Not Cancer Driver No 1 hippie 54 0 0 0 0
FBXO6 FBXO6 Q9NRD1 F-box only protein 6 chr1 Not Cancer Driver No 1 hippie 31 27 3 3 0
FGF14_ENST00000376143 FGF14 Q92915 Fibroblast growth factor 14 chr13 Not Cancer Driver No 1 hippie, biogrid 72 93 30 30 1
FKBP3_ENST00000396062 FKBP3 Q00688 Peptidyl-prolyl cis-trans isomerase FKBP3 chr14 Not Cancer Driver No 1 hippie 27 131 17 17 0
FLII FLII Q13045 Protein flightless-1 homolog chr17 Not Cancer Driver No 1 hippie 128 206 32 32 0
FZD10 FZD10 Q9ULW2 Frizzled-10 chr12 Not Cancer Driver No 2 hippie, biogrid 148 65 15 15 0
G3BP1 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 Not Cancer Driver No 1 hippie 85 352 65 65 0
GCH1_ENST00000622544 GCH1 P30793 GTP cyclohydrolase 1 chr14 Not Cancer Driver No 1 hippie, biogrid 20 99 5 5 38
GOLM1_ENST00000388711 GOLM1 Q8NBJ4 Golgi membrane protein 1 chr9 Not Cancer Driver No 1 hippie 46 274 25 25 0
GPR17 GPR17 Q13304 Uracil nucleotide/cysteinyl leukotriene receptor chr2 Not Cancer Driver No 1 hippie, biogrid 57 16 4 4 0
GPR183 GPR183 P32249 G-protein coupled receptor 183 chr13 Not Cancer Driver No 3 hippie, biogrid 53 25 3 3 0
GYPB GYPB P06028 Glycophorin-B chr4 Not Cancer Driver No 2 hippie, biogrid 40 0 0 0 0
HNRNPA1 HNRNPA1 P09651 Heterogeneous nuclear ribonucleoprotein A1 chr12 Not Cancer Driver No 1 hippie 70 290 58 58 4
HNRNPM HNRNPM P52272 Heterogeneous nuclear ribonucleoprotein M chr19 Not Cancer Driver No 1 hippie 108 463 67 67 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 Not Cancer Driver No 1 hippie 77 504 45 45 0
HTR2C HTR2C P28335 5-hydroxytryptamine receptor 2C chrX Not Cancer Driver No 1 hippie, biogrid 140 40 11 11 0
IGF2BP3 IGF2BP3 O00425 Insulin-like growth factor 2 mRNA-binding protein 3 chr7 Not Cancer Driver No 1 hippie 79 264 40 40 0
ILF2 ILF2 Q12905 Interleukin enhancer-binding factor 2 chr1 Not Cancer Driver No 1 hippie 36 92 9 9 0
JUN JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 35 281 25 25 0
LMBR1L LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 57 4 0 0 0
LRRC59 LRRC59 Q96AG4 Leucine-rich repeat-containing protein 59 chr17 Not Cancer Driver No 1 hippie 33 122 15 15 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 hippie 519 90 17 17 23
MAP1LC3B MAP1LC3B Q9GZQ8 Microtubule-associated proteins 1A/1B light chain 3B chr16 Not Cancer Driver No 1 hippie 10 17 1 1 0
MRE11 MRE11 P49959 Double-strand break repair protein MRE11 chr11 Not Cancer Driver No 1 hippie 84 292 35 35 1
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
NDUFB8 NDUFB8 O95169 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 28 64 11 11 3
NECTIN4 NECTIN4 Q96NY8 Nectin-4 chr1 Not Cancer Driver No 1 hippie 92 279 50 50 1
NELFB_ENST00000634710 NELFB Q8WX92-2 Isoform 2 of Negative elongation factor B chr9 Not Cancer Driver No 1 hippie 69 132 3 3 0
NMT1_ENST00000258960 NMT1 P30419 Glycylpeptide N-tetradecanoyltransferase 1 chr17 Not Cancer Driver No 1 hippie 62 169 22 22 0
NR2C2_ENST00000393102 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 hippie 62 186 24 24 0
OPN3 OPN3 Q9H1Y3 Opsin-3 chr1 Not Cancer Driver No 3 hippie, biogrid 39 6 1 1 0
P2RX4_ENST00000337233 P2RX4 Q99571 P2X purinoceptor 4 chr12 Not Cancer Driver No 3 hippie, biogrid 36 0 0 0 0
P2RY6_ENST00000540342 P2RY6 Q15077 P2Y purinoceptor 6 chr11 Not Cancer Driver No 1 hippie 50 10 5 5 0
PIP4P1_ENST00000250489 PIP4P1 Q86T03 Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase chr14 Not Cancer Driver No 1 hippie 36 78 4 4 0
PIP4P2 PIP4P2 Q8N4L2 Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase chr8 Not Cancer Driver No 1 hippie 41 46 4 4 0
PLD1 PLD1 Q13393 Phospholipase D1 chr3 Not Cancer Driver No 1 biogrid 181 133 32 32 1
PLD6 PLD6 Q8N2A8 Mitochondrial cardiolipin hydrolase chr17 Not Cancer Driver No 1 biogrid 27 24 6 6 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PNKD PNKD Q8N490 Probable hydrolase PNKD chr2 Not Cancer Driver No 1 hippie, biogrid 52 160 25 25 2
PTAFR_ENST00000305392 PTAFR P25105 Platelet-activating factor receptor chr1 Not Cancer Driver No 1 hippie, biogrid 42 0 0 0 0
PTGER3_ENST00000370931 PTGER3 P43115 Prostaglandin E2 receptor EP3 subtype chr1 Not Cancer Driver No 3 hippie, biogrid 79 17 2 2 0
RFC4_ENST00000296273 RFC4 P35249 Replication factor C subunit 4 chr3 Not Cancer Driver No 1 hippie 58 50 8 8 0
RTCB RTCB Q9Y3I0 RNA-splicing ligase RtcB homolog chr22 Not Cancer Driver No 1 hippie 57 74 7 7 0
RTRAF RTRAF Q9Y224 RNA transcription, translation and transport factor protein chr14 Not Cancer Driver No 1 hippie 24 35 1 1 0
SCN2B SCN2B O60939 Sodium channel subunit beta-2 chr11 Not Cancer Driver No 1 hippie, biogrid 46 52 7 7 2
SEC62 SEC62 Q99442 Translocation protein SEC62 chr3 Not Cancer Driver No 1 hippie, biogrid 41 211 23 23 0
SIGLECL1 SIGLECL1 Q8N7X8 SIGLEC family-like protein 1 chr19 Not Cancer Driver No 2 hippie, biogrid 56 35 14 14 0
SLC15A3 SLC15A3 Q8IY34 Solute carrier family 15 member 3 chr11 Not Cancer Driver No 1 hippie 63 43 1 1 0
SMDT1 SMDT1 Q9H4I9 Essential MCU regulator, mitochondrial chr22 Not Cancer Driver No 1 hippie 6 6 0 0 0
SPN_ENST00000395389 SPN P16150 Leukosialin chr16 Not Cancer Driver No 3 hippie, biogrid 46 357 35 35 0
STC2 STC2 O76061 Stanniocalcin-2 chr5 Not Cancer Driver No 1 hippie, biogrid 71 112 29 29 0
STX12 STX12 Q86Y82 Syntaxin-12 chr1 Not Cancer Driver No 3 hippie, biogrid 21 156 9 9 0
SYT1_ENST00000393240 SYT1 P21579 Synaptotagmin-1 chr12 Not Cancer Driver No 2 hippie, biogrid 104 103 36 36 5
SYT2_ENST00000367268 SYT2 Q8N9I0 Synaptotagmin-2 chr1 Not Cancer Driver No 1 hippie, biogrid 73 141 24 24 3
TACSTD2 TACSTD2 P09758 Tumor-associated calcium signal transducer 2 chr1 Not Cancer Driver No 1 hippie, biogrid 22 27 1 1 0
TNFSF13B TNFSF13B Q9Y275 Tumor necrosis factor ligand superfamily member 13B chr13 Not Cancer Driver No 1 hippie 41 91 15 15 0
TNFSF14 TNFSF14 O43557 Tumor necrosis factor ligand superfamily member 14 chr19 Not Cancer Driver No 1 hippie, biogrid 58 18 1 1 0
TPST2 TPST2 O60704 Protein-tyrosine sulfotransferase 2 chr22 Not Cancer Driver No 1 hippie, biogrid 47 48 6 6 0
TULP3_ENST00000448120 TULP3 O75386 Tubby-related protein 3 chr12 Not Cancer Driver No 1 hippie 66 218 29 29 0
UNC93B1 UNC93B1 Q9H1C4 Protein unc-93 homolog B1 chr11 Not Cancer Driver No 1 hippie 57 127 5 5 0
UXS1_ENST00000409501 UXS1 Q8NBZ7 UDP-glucuronic acid decarboxylase 1 chr2 Not Cancer Driver No 2 hippie, biogrid 70 69 9 9 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
VTI1B VTI1B Q9UEU0 Vesicle transport through interaction with t-SNAREs homolog 1B chr14 Not Cancer Driver No 3 hippie, biogrid 25 192 20 20 0
XPO1_ENST00000406957 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie 140 33 9 9 0
YBX3 YBX3 P16989 Y-box-binding protein 3 chr12 Not Cancer Driver No 1 hippie 49 359 47 47 0
ZDHHC5 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 Not Cancer Driver No 1 hippie 89 462 63 63 0
ZWINT ZWINT O95229 ZW10 interactor chr10 Not Cancer Driver No 1 hippie 65 168 44 44 0