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EGLN1 ,EGLN1 ,Q9GZT9
  • Uniprot Accession= Q9GZT9
  • Ensembl Transcript= ENST00000366641.3
  • Uniprot Name= EGLN1
  • Name= Egl nine homolog 1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 15
  • Number of Interaction partner in biogrid: 15
  • Number of Interaction partner in hippie: 63
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AATK AATK Q6ZMQ8 Serine/threonine-protein kinase LMTK1 chr17 Not Cancer Driver No 1 intact 108 912 75 75 0
AKAP1_ENST00000539273 AKAP1 Q92667 A-kinase anchor protein 1, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 107 537 67 67 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 Census, Compendium Yes 1 hippie 108 158 24 24 4
AKT2 AKT2 P31751 RAC-beta serine/threonine-protein kinase chr19 Census Yes 1 hippie 77 84 9 9 2
ALK ALK Q9UM73 ALK tyrosine kinase receptor chr2 Census, Compendium Yes 1 intact 303 575 114 114 16
APOBEC3C APOBEC3C Q9NRW3 DNA dC->dU-editing enzyme APOBEC-3C chr22 Not Cancer Driver No 1 hippie, biogrid 28 2 0 0 0
ARNT ARNT P27540 Aryl hydrocarbon receptor nuclear translocator chr1 Census Yes 1 hippie 77 511 56 56 0
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 193 1182 172 172 0
BTF3 BTF3 P20290 Transcription factor BTF3 chr5 Not Cancer Driver No 1 hippie, biogrid 27 192 24 24 0
CANX_ENST00000504734 CANX P27824 Calnexin chr5 Not Cancer Driver No 1 intact, hippie 65 334 38 38 0
CBFA2T3 CBFA2T3 O75081 Protein CBFA2T3 chr16 Census, Compendium Yes 1 hippie 83 502 70 70 0
CBWD1_ENST00000356521 CBWD1 Q9BRT8 COBW domain-containing protein 1 chr9 Not Cancer Driver No 3 intact, hippie, biogrid 27 62 8 8 0
CBWD2 CBWD2 Q8IUF1 COBW domain-containing protein 2 chr2 Not Cancer Driver No 1 hippie, biogrid 20 54 6 6 0
CITED1_ENST00000246139 CITED1 Q99966 Cbp/p300-interacting transactivator 1 chrX Not Cancer Driver No 1 hippie, biogrid 24 166 21 21 0
CUL3 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 hippie 123 167 23 23 3
EEF1AKMT1_ENST00000382754 EEF1AKMT1 Q8WVE0 EEF1A lysine methyltransferase 1 chr13 Not Cancer Driver No 1 hippie 28 22 1 1 0
EGLN1 EGLN1 Q9GZT9 Egl nine homolog 1 chr1 Not Cancer Driver No 1 hippie 35 206 8 8 2
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
EPAS1 EPAS1 Q99814 Endothelial PAS domain-containing protein 1 chr2 Census, Compendium Yes 2 intact, hippie 120 449 53 53 6
ERP29 ERP29 P30040 Endoplasmic reticulum resident protein 29 chr12 Not Cancer Driver No 1 intact, hippie 29 34 5 5 0
EZR EZR P15311 Ezrin chr6 Census Yes 1 intact, hippie 66 295 35 35 0
FGFR3_ENST00000440486 FGFR3 P22607 Fibroblast growth factor receptor 3 chr4 Census, Compendium Yes 1 intact 173 241 26 26 37
FGFR4 FGFR4 P22455 Fibroblast growth factor receptor 4 chr5 Census, Compendium Yes 1 intact 113 162 28 28 0
FKBP4 FKBP4 Q02790 Peptidyl-prolyl cis-trans isomerase FKBP4 chr12 Not Cancer Driver No 1 hippie 46 134 12 12 0
FKBP5 FKBP5 Q13451 Peptidyl-prolyl cis-trans isomerase FKBP5 chr6 Not Cancer Driver No 1 intact, hippie 70 150 20 20 0
FKBP8_ENST00000222308 FKBP8 Q14318 Peptidyl-prolyl cis-trans isomerase FKBP8 chr19 Not Cancer Driver No 2 hippie, biogrid 71 160 25 25 0
GPLD1 GPLD1 P80108 Phosphatidylinositol-glycan-specific phospholipase D chr6 Not Cancer Driver No 1 hippie 153 36 9 9 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 Census Yes 1 hippie 118 435 51 51 0
HIF3A HIF3A Q9Y2N7 Hypoxia-inducible factor 3-alpha chr19 Not Cancer Driver No 1 hippie 146 361 94 94 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 1 hippie 106 257 37 37 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 1 hippie 100 254 43 43 0
IKBKG_ENST00000611071 IKBKG Q9Y6K9 NF-kappa-B essential modulator chrX Not Cancer Driver No 1 hippie 6 301 6 6 22
ING4 ING4 Q9UNL4 Inhibitor of growth protein 4 chr12 Not Cancer Driver No 1 hippie 31 108 15 15 0
JUN JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 35 281 25 25 0
KEAP1_ENST00000393623 KEAP1 Q14145 Kelch-like ECH-associated protein 1 chr19 Census, Compendium Yes 1 hippie 237 57 12 12 0
KRAS KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 1 intact, hippie 788 7 2 2 27
LCK LCK P06239 Tyrosine-protein kinase Lck chr1 Census Yes 1 hippie, biogrid 86 94 13 13 1
LIMD1 LIMD1 Q9UGP4 LIM domain-containing protein 1 chr3 Not Cancer Driver No 1 hippie 58 428 36 36 0
MAGEA11 MAGEA11 P43364 Melanoma-associated antigen 11 chrX Not Cancer Driver No 1 hippie 115 217 49 49 0
MKS1 MKS1 Q9NXB0 Meckel syndrome type 1 protein chr17 Not Cancer Driver No 1 intact, hippie 82 152 23 23 2
NAA40 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 22 30 3 3 0
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 Census, Compendium Yes 1 intact 249 57 21 21 0
OS9 OS9 Q13438 Protein OS-9 chr12 Not Cancer Driver No 1 intact, hippie 72 451 49 49 0
OSR1 OSR1 Q8TAX0 Protein odd-skipped-related 1 chr2 Not Cancer Driver No 1 hippie 57 67 17 17 0
PEX19 PEX19 P40855 Peroxisomal biogenesis factor 19 chr1 Not Cancer Driver No 1 hippie, biogrid 41 266 38 38 0
PKM_ENST00000335181 PKM P14618 Pyruvate kinase PKM chr15 Not Cancer Driver No 1 hippie 78 58 13 13 0
PLD1 PLD1 Q13393 Phospholipase D1 chr3 Not Cancer Driver No 1 hippie 181 133 32 32 1
PLD2 PLD2 O14939 Phospholipase D2 chr17 Not Cancer Driver No 1 hippie 107 97 8 8 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
POLR2A POLR2A P24928-2 Isoform 2 of DNA-directed RNA polymerase II subunit RPB1 chr17 Census Yes 1 hippie 56 230 20 20 0
POLR2C POLR2C P19387 DNA-directed RNA polymerase II subunit RPB3 chr16 Not Cancer Driver No 1 hippie, biogrid 34 108 11 11 0
PTGES3_ENST00000262033 PTGES3 Q15185 Prostaglandin E synthase 3 chr12 Not Cancer Driver No 2 hippie, biogrid 11 52 3 3 0
RFPL4B RFPL4B Q6ZWI9 Ret finger protein-like 4B chr6 Not Cancer Driver No 1 hippie, biogrid 65 0 0 0 0
RHOBTB3 RHOBTB3 O94955 Rho-related BTB domain-containing protein 3 chr5 Not Cancer Driver No 1 hippie 67 34 2 2 0
RMDN3 RMDN3 Q96TC7 Regulator of microtubule dynamics protein 3 chr15 Not Cancer Driver No 1 hippie, biogrid 45 196 17 17 0
RUNX3_ENST00000308873 RUNX3 Q13761 Runt-related transcription factor 3 chr1 Not Cancer Driver No 1 hippie 59 331 45 45 0
SDCBP_ENST00000260130 SDCBP O00560 Syntenin-1 chr8 Not Cancer Driver No 1 hippie 39 17 2 2 0
SH3KBP1 SH3KBP1 Q96B97 SH3 domain-containing kinase-binding protein 1 chrX Not Cancer Driver No 1 hippie 102 530 82 82 0
SIAH2 SIAH2 O43255 E3 ubiquitin-protein ligase SIAH2 chr3 Not Cancer Driver No 1 hippie 48 68 3 3 0
SNUPN_ENST00000564675 SNUPN O95149 Snurportin-1 chr15 Not Cancer Driver No 1 hippie, biogrid 45 137 17 17 0
SPRY2 SPRY2 O43597 Protein sprouty homolog 2 chr13 Not Cancer Driver No 1 hippie 46 169 29 29 1
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 Census Yes 1 hippie 53 130 11 11 1
TBK1 TBK1 Q9UHD2 Serine/threonine-protein kinase TBK1 chr12 Not Cancer Driver No 1 hippie 101 42 5 5 12
TET2 TET2 Q6N021 Methylcytosine dioxygenase TET2 chr4 Census, Compendium Yes 1 hippie 191 1663 176 176 1
TET3 TET3 O43151 Methylcytosine dioxygenase TET3 chr2 Not Cancer Driver No 1 hippie 208 1272 152 152 6
TUBA4A TUBA4A P68366 Tubulin alpha-4A chain chr2 Not Cancer Driver No 1 hippie, biogrid 73 39 4 4 5
VHL VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 Census, Compendium Yes 1 hippie 142 117 36 36 133
ZNF281_ENST00000367353 ZNF281 Q9Y2X9 Zinc finger protein 281 chr1 Not Cancer Driver No 1 intact, hippie 92 709 67 67 0