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EFNA4_ENST00000368409 ,EFNA4 ,P52798
  • Uniprot Accession= P52798
  • Ensembl Transcript= ENST00000368409.7
  • Uniprot Name= EFNA4
  • Name= Ephrin-A4
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 2
  • Number of Interaction partner in biogrid: 116
  • Number of Interaction partner in hippie: 129
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ARL6IP5 ARL6IP5 O75915 PRA1 family protein 3 chr3 Not Cancer Driver No 1 hippie, biogrid 26 0 0 0 0
ARVCF ARVCF O00192 Armadillo repeat protein deleted in velo-cardio-facial syndrome chr22 Not Cancer Driver No 1 hippie, biogrid 115 618 68 68 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 Census, Compendium Yes 1 hippie, biogrid 469 225 39 39 41
ATR ATR Q13535 Serine/threonine-protein kinase ATR chr3 Census, Compendium Yes 1 hippie, biogrid 338 106 14 14 1
ATRIP ATRIP Q8WXE1 ATR-interacting protein chr3 Not Cancer Driver No 1 hippie, biogrid 76 383 32 32 0
BCL2L13_ENST00000317582 BCL2L13 Q9BXK5 Bcl-2-like protein 13 chr22 Not Cancer Driver No 1 hippie, biogrid 49 291 30 30 0
BTAF1 BTAF1 O14981 TATA-binding protein-associated factor 172 chr10 Not Cancer Driver No 1 hippie, biogrid 215 360 52 52 0
BZW1_ENST00000409600 BZW1 Q7L1Q6 eIF5-mimic protein 2 chr2 Not Cancer Driver No 1 hippie, biogrid 43 49 8 8 0
BZW2_ENST00000258761 BZW2 Q9Y6E2 eIF5-mimic protein 1 chr7 Not Cancer Driver No 1 hippie, biogrid 41 58 8 8 0
C19orf25 C19orf25 Q9UFG5 UPF0449 protein C19orf25 chr19 Not Cancer Driver No 1 hippie, biogrid 6 117 6 6 0
CCNB2 CCNB2 O95067 G2/mitotic-specific cyclin-B2 chr15 Not Cancer Driver No 1 hippie, biogrid 33 103 10 10 0
CDK5RAP3_ENST00000338399 CDK5RAP3 Q96JB5 CDK5 regulatory subunit-associated protein 3 chr17 Not Cancer Driver No 1 hippie, biogrid 50 99 20 20 0
CENPH CENPH Q9H3R5 Centromere protein H chr5 Not Cancer Driver No 1 hippie, biogrid 28 85 7 7 0
CENPI_ENST00000423383 CENPI Q92674 Centromere protein I chrX Not Cancer Driver No 1 hippie, biogrid 107 82 7 7 0
CENPK_ENST00000514814 CENPK Q9BS16 Centromere protein K chr5 Not Cancer Driver No 1 hippie, biogrid 28 91 8 8 0
CIP2A CIP2A Q8TCG1 Protein CIP2A chr3 Not Cancer Driver No 1 hippie 118 240 31 31 0
COG1 COG1 Q8WTW3 Conserved oligomeric Golgi complex subunit 1 chr17 Not Cancer Driver No 1 hippie, biogrid 88 204 18 18 0
COG2 COG2 Q14746 Conserved oligomeric Golgi complex subunit 2 chr1 Not Cancer Driver No 1 hippie, biogrid 90 105 16 16 1
COG3 COG3 Q96JB2 Conserved oligomeric Golgi complex subunit 3 chr13 Not Cancer Driver No 1 hippie, biogrid 72 109 7 7 0
COG4 COG4 Q9H9E3 Conserved oligomeric Golgi complex subunit 4 chr16 Not Cancer Driver No 1 hippie, biogrid 92 55 10 10 2
COG5_ENST00000347053 COG5 Q9UP83 Conserved oligomeric Golgi complex subunit 5 chr7 Not Cancer Driver No 1 hippie, biogrid 101 118 23 23 0
COG6 COG6 Q9Y2V7 Conserved oligomeric Golgi complex subunit 6 chr13 Not Cancer Driver No 1 hippie, biogrid 83 141 16 16 1
COG7 COG7 P83436 Conserved oligomeric Golgi complex subunit 7 chr16 Not Cancer Driver No 1 hippie, biogrid 85 60 6 6 0
COG8 COG8 H3BQV3 Conserved oligomeric Golgi complex subunit 8 chr16 Not Cancer Driver No 1 hippie, biogrid 112 37 6 6 0
COQ8B COQ8B Q96D53 Atypical kinase COQ8B, mitochondrial chr19 Not Cancer Driver No 1 hippie 53 117 15 15 8
CXCR4_ENST00000241393 CXCR4 P61073 C-X-C chemokine receptor type 4 chr2 Census, Compendium Yes 1 hippie, biogrid 62 5 1 1 0
DMXL2_ENST00000251076 DMXL2 Q8TDJ6 DmX-like protein 2 chr15 Not Cancer Driver No 1 hippie, biogrid 428 738 102 102 2
DNAAF5 DNAAF5 Q86Y56 Dynein axonemal assembly factor 5 chr7 Not Cancer Driver No 1 hippie, biogrid 89 81 0 0 1
DNM1 DNM1 Q05193 Dynamin-1 chr9 Not Cancer Driver No 1 hippie, biogrid 98 280 23 23 4
DNM1L_ENST00000549701 DNM1L O00429 Dynamin-1-like protein chr12 Not Cancer Driver No 1 hippie, biogrid 67 212 23 23 7
DNM2_ENST00000355667 DNM2 P50570 Dynamin-2 chr19 Census Yes 1 hippie, biogrid 138 270 43 43 22
DNM3_ENST00000355305 DNM3 Q9UQ16 Dynamin-3 chr1 Not Cancer Driver No 1 hippie, biogrid 166 257 45 45 0
DOCK4 DOCK4 Q8N1I0 Dedicator of cytokinesis protein 4 chr7 Not Cancer Driver No 1 hippie, biogrid 331 397 80 80 0
DYM DYM Q7RTS9 Dymeclin chr18 Not Cancer Driver No 1 hippie, biogrid 78 21 0 0 3
EDC4 EDC4 Q6P2E9 Enhancer of mRNA-decapping protein 4 chr16 Not Cancer Driver No 1 hippie, biogrid 144 702 69 69 0
EPHA2 EPHA2 P29317 Ephrin type-A receptor 2 chr1 Compendium Yes 2 hippie, biogrid 171 187 39 39 3
EPHA3 EPHA3 P29320 Ephrin type-A receptor 3 chr3 Census, Compendium Yes 1 hippie 346 74 28 28 0
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 Not Cancer Driver No 3 intact, hippie, biogrid 182 140 24 24 0
EPHA5_ENST00000273854 EPHA5 P54756 Ephrin type-A receptor 5 chr4 Not Cancer Driver No 1 hippie 341 83 39 39 0
EPHA6_ENST00000502694 EPHA6 Q9UF33-2 Isoform 2 of Ephrin type-A receptor 6 chr3 Not Cancer Driver No 2 hippie, biogrid 123 38 16 16 0
EPHA7 EPHA7 Q15375 Ephrin type-A receptor 7 chr6 Census, Compendium Yes 2 intact, hippie 280 71 15 15 0
EPHA8 EPHA8 P29322 Ephrin type-A receptor 8 chr1 Not Cancer Driver No 2 hippie, biogrid 197 121 17 17 0
EXOC1 EXOC1 Q9NV70 Exocyst complex component 1 chr4 Not Cancer Driver No 1 hippie, biogrid 128 154 22 22 0
EXOC8 EXOC8 Q8IYI6 Exocyst complex component 8 chr1 Not Cancer Driver No 1 hippie, biogrid 84 195 21 21 0
GBF1 GBF1 Q92538 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 chr10 Not Cancer Driver No 1 hippie, biogrid 216 669 76 76 0
GLMN GLMN Q92990 Glomulin chr1 Not Cancer Driver No 1 hippie, biogrid 49 37 6 6 0
GPAA1 GPAA1 O43292 Glycosylphosphatidylinositol anchor attachment 1 protein chr8 Not Cancer Driver No 1 hippie, biogrid 55 20 3 3 5
HEATR3 HEATR3 Q7Z4Q2 HEAT repeat-containing protein 3 chr16 Not Cancer Driver No 1 hippie, biogrid 73 134 10 10 0
HEATR5B HEATR5B Q9P2D3 HEAT repeat-containing protein 5B chr2 Not Cancer Driver No 1 hippie, biogrid 250 163 14 14 0
INTS1 INTS1 Q8N201 Integrator complex subunit 1 chr7 Not Cancer Driver No 1 hippie, biogrid 234 368 43 43 1
INTS12 INTS12 Q96CB8 Integrator complex subunit 12 chr4 Not Cancer Driver No 1 hippie, biogrid 45 382 40 40 0
INTS2 INTS2 Q9H0H0 Integrator complex subunit 2 chr17 Not Cancer Driver No 1 hippie, biogrid 149 97 8 8 0
INTS5 INTS5 Q6P9B9 Integrator complex subunit 5 chr11 Not Cancer Driver No 1 hippie, biogrid 123 189 22 22 0
KDM8_ENST00000286096 KDM8 Q8N371 Bifunctional peptidase and arginyl-hydroxylase JMJD5 chr16 Not Cancer Driver No 1 hippie, biogrid 52 29 6 6 0
KIAA1586 KIAA1586 Q9HCI6 E3 SUMO-protein ligase KIAA1586 chr6 Not Cancer Driver No 1 hippie, biogrid 87 129 14 14 0
KIDINS220 KIDINS220 Q9ULH0 Kinase D-interacting substrate of 220 kDa chr2 Not Cancer Driver No 1 hippie, biogrid 245 683 113 113 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie, biogrid 222 774 102 102 2
KNTC1 KNTC1 P50748 Kinetochore-associated protein 1 chr12 Not Cancer Driver No 1 hippie, biogrid 250 70 9 9 0
LRBA LRBA P50851 Lipopolysaccharide-responsive and beige-like anchor protein chr4 Not Cancer Driver No 1 hippie, biogrid 350 709 82 82 1
MAP2K4_ENST00000353533 MAP2K4 P45985 Dual specificity mitogen-activated protein kinase kinase 4 chr17 Census, Compendium Yes 1 hippie 89 137 28 28 0
MINPP1 MINPP1 Q9UNW1 Multiple inositol polyphosphate phosphatase 1 chr10 Not Cancer Driver No 1 hippie, biogrid 52 46 2 2 2
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 110 101 8 8 0
MTX1 MTX1 Q13505 Metaxin-1 chr1 Not Cancer Driver No 1 hippie, biogrid 25 221 7 7 0
MZT2B_ENST00000281871 MZT2B Q6NZ67 Mitotic-spindle organizing protein 2B chr2 Not Cancer Driver No 1 hippie, biogrid 14 113 14 14 0
NBAS NBAS A2RRP1 NBAS subunit of NRZ tethering complex chr2 Not Cancer Driver No 1 hippie, biogrid 365 246 41 41 5
NCAPD3 NCAPD3 P42695 Condensin-2 complex subunit D3 chr11 Not Cancer Driver No 1 hippie, biogrid 193 304 42 42 1
NDUFAF1 NDUFAF1 Q9Y375 Complex I intermediate-associated protein 30, mitochondrial chr15 Not Cancer Driver No 1 hippie, biogrid 44 63 8 8 4
NF1 NF1 P21359 Neurofibromin chr17 Census, Compendium Yes 1 hippie, biogrid 375 406 47 47 85
NOP58 NOP58 Q9Y2X3 Nucleolar protein 58 chr2 Not Cancer Driver No 1 hippie, biogrid 47 156 14 14 0
NR6A1 NR6A1 Q15406 Nuclear receptor subfamily 6 group A member 1 chr9 Not Cancer Driver No 1 hippie, biogrid 43 124 4 4 0
NUP107 NUP107 P57740 Nuclear pore complex protein Nup107 chr12 Not Cancer Driver No 1 hippie, biogrid 127 183 26 26 5
NXF1_ENST00000294172 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 100 163 32 32 0
PDS5A PDS5A Q29RF7 Sister chromatid cohesion protein PDS5 homolog A chr4 Not Cancer Driver No 1 hippie, biogrid 150 295 34 34 0
PDS5B PDS5B Q9NTI5 Sister chromatid cohesion protein PDS5 homolog B chr13 Not Cancer Driver No 1 hippie, biogrid 174 455 61 61 0
PLAA PLAA Q9Y263 Phospholipase A-2-activating protein chr9 Not Cancer Driver No 1 hippie, biogrid 78 150 14 14 2
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 Not Cancer Driver No 1 hippie, biogrid 538 421 61 61 2
RINT1 RINT1 Q6NUQ1 RAD50-interacting protein 1 chr7 Not Cancer Driver No 1 hippie, biogrid 84 55 3 3 2
RMND1 RMND1 Q9NWS8 Required for meiotic nuclear division protein 1 homolog chr6 Not Cancer Driver No 1 hippie, biogrid 46 83 11 11 1
RUNDC1 RUNDC1 Q96C34 RUN domain-containing protein 1 chr17 Not Cancer Driver No 1 hippie, biogrid 65 238 21 21 0
SIDT2_ENST00000620360 SIDT2 Q8NBJ9 SID1 transmembrane family member 2 chr11 Not Cancer Driver No 1 hippie, biogrid 113 23 6 6 0
SOS1_ENST00000402219 SOS1 Q07889 Son of sevenless homolog 1 chr2 Compendium Yes 1 hippie, biogrid 197 458 62 62 38
SPAG9 SPAG9 O60271 C-Jun-amino-terminal kinase-interacting protein 4 chr17 Not Cancer Driver No 1 hippie, biogrid 128 841 81 81 0
SPC24 SPC24 Q8NBT2 Kinetochore protein Spc24 chr19 Not Cancer Driver No 1 hippie, biogrid 9 88 5 5 0
SPC25 SPC25 Q9HBM1 Kinetochore protein Spc25 chr2 Not Cancer Driver No 1 hippie, biogrid 15 34 2 2 0
SPCS1 SPCS1 Q9Y6A9 Signal peptidase complex subunit 1 chr3 Not Cancer Driver No 1 hippie, biogrid 18 81 9 9 0
SPCS2 SPCS2 Q15005 Signal peptidase complex subunit 2 chr11 Not Cancer Driver No 1 hippie, biogrid 17 0 0 0 0
STAG2_ENST00000371157 STAG2 Q8N3U4 Cohesin subunit SA-2 chrX Census, Compendium Yes 1 hippie, biogrid 179 330 46 46 3
STK39 STK39 Q9UEW8 STE20/SPS1-related proline-alanine-rich protein kinase chr2 Not Cancer Driver No 1 hippie, biogrid 64 182 19 19 0
SYMPK SYMPK Q92797 Symplekin chr19 Not Cancer Driver No 1 hippie, biogrid 156 398 42 42 0
TARBP1 TARBP1 Q13395 Probable methyltransferase TARBP1 chr1 Not Cancer Driver No 1 hippie, biogrid 165 90 4 4 0
TBCD TBCD Q9BTW9 Tubulin-specific chaperone D chr17 Not Cancer Driver No 1 hippie, biogrid 156 60 9 9 11
TBRG4_ENST00000494076 TBRG4 Q969Z0 FAST kinase domain-containing protein 4 chr7 Not Cancer Driver No 1 hippie, biogrid 74 60 2 2 0
TEDC1_ENST00000392523 TEDC1 Q86SX3 Tubulin epsilon and delta complex protein 1 chr14 Not Cancer Driver No 1 hippie 25 160 6 6 0
TGFBRAP1 TGFBRAP1 Q8WUH2 Transforming growth factor-beta receptor-associated protein 1 chr2 Not Cancer Driver No 1 hippie, biogrid 127 37 8 8 0
THADA_ENST00000405975 THADA Q6YHU6 Thyroid adenoma-associated protein chr2 Not Cancer Driver No 1 hippie, biogrid 204 63 6 6 0
THEM6 THEM6 Q8WUY1 Protein THEM6 chr8 Not Cancer Driver No 1 hippie, biogrid 3 7 0 0 0
TMEM147 TMEM147 Q9BVK8 Transmembrane protein 147 chr19 Not Cancer Driver No 1 hippie 23 0 0 0 0
TMEM214 TMEM214 Q6NUQ4 Transmembrane protein 214 chr2 Not Cancer Driver No 1 hippie, biogrid 68 123 9 9 0
TMEM245 TMEM245 Q9H330 Transmembrane protein 245 chr9 Not Cancer Driver No 1 hippie, biogrid 64 100 3 3 0
TNPO2 TNPO2 O14787 Transportin-2 chr19 Not Cancer Driver No 1 hippie, biogrid 99 76 10 10 0
TNPO3 TNPO3 Q9Y5L0 Transportin-3 chr7 Not Cancer Driver No 1 hippie, biogrid 122 12 1 1 1
TPCN1_ENST00000335509 TPCN1 Q9ULQ1 Two pore channel protein 1 chr12 Not Cancer Driver No 1 hippie, biogrid 114 99 18 18 0
TRARG1 TRARG1 Q8IXB3 Trafficking regulator of GLUT4 1 chr17 Not Cancer Driver No 1 hippie 33 83 11 11 0
TTI1 TTI1 O43156 TELO2-interacting protein 1 homolog chr20 Not Cancer Driver No 1 hippie, biogrid 136 93 13 13 0
TTI2_ENST00000360742 TTI2 Q6NXR4 TELO2-interacting protein 2 chr8 Not Cancer Driver No 1 hippie, biogrid 55 80 8 8 1
TTYH3 TTYH3 Q9C0H2 Protein tweety homolog 3 chr7 Not Cancer Driver No 1 hippie, biogrid 48 91 14 14 0
TUBGCP3 TUBGCP3 Q96CW5 Gamma-tubulin complex component 3 chr13 Not Cancer Driver No 1 hippie, biogrid 109 156 16 16 0
UCKL1 UCKL1 Q9NWZ5 Uridine-cytidine kinase-like 1 chr20 Not Cancer Driver No 1 hippie, biogrid 54 134 15 15 0
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 hippie, biogrid 109 141 24 24 0
UGDH_ENST00000506179 UGDH O60701 UDP-glucose 6-dehydrogenase chr4 Not Cancer Driver No 1 hippie, biogrid 54 39 4 4 5
UPRT UPRT Q96BW1 Uracil phosphoribosyltransferase homolog chrX Not Cancer Driver No 1 hippie, biogrid 64 76 15 15 0
URB1 URB1 O60287 Nucleolar pre-ribosomal-associated protein 1 chr21 Not Cancer Driver No 1 hippie, biogrid 93 180 2 2 0
UST UST Q9Y2C2 Uronyl 2-sulfotransferase chr6 Not Cancer Driver No 1 hippie, biogrid 70 57 8 8 0
UTP20 UTP20 O75691 Small subunit processome component 20 homolog chr12 Not Cancer Driver No 1 hippie, biogrid 324 314 35 35 0
VPS18 VPS18 Q9P253 Vacuolar protein sorting-associated protein 18 homolog chr15 Not Cancer Driver No 1 hippie, biogrid 96 86 7 7 0
VPS50 VPS50 Q96JG6 Syndetin chr7 Not Cancer Driver No 1 hippie 175 171 32 32 0
VPS51 VPS51 Q9UID3 Vacuolar protein sorting-associated protein 51 homolog chr11 Not Cancer Driver No 1 hippie, biogrid 75 150 11 11 1
VPS52 VPS52 Q8N1B4 Vacuolar protein sorting-associated protein 52 homolog chr6 Not Cancer Driver No 1 hippie, biogrid 89 36 5 5 0
VPS53 VPS53 Q5VIR6 Vacuolar protein sorting-associated protein 53 homolog chr17 Not Cancer Driver No 1 hippie, biogrid 83 172 27 27 1
VPS54 VPS54 Q9P1Q0 Vacuolar protein sorting-associated protein 54 chr2 Not Cancer Driver No 1 hippie, biogrid 93 152 14 14 0
WASHC5 WASHC5 Q12768 WASH complex subunit 5 chr8 Not Cancer Driver No 1 hippie 152 23 6 6 6
WFS1_ENST00000503569 WFS1 O76024 Wolframin chr4 Not Cancer Driver No 1 hippie, biogrid 105 203 10 10 39
XPO5 XPO5 Q9HAV4 Exportin-5 chr6 Not Cancer Driver No 1 hippie, biogrid 112 64 7 7 0
XPO6 XPO6 Q96QU8 Exportin-6 chr16 Not Cancer Driver No 1 hippie, biogrid 133 29 1 1 0
XPO7 XPO7 Q9UIA9 Exportin-7 chr8 Not Cancer Driver No 1 hippie, biogrid 132 59 8 8 0
XPOT XPOT O43592 Exportin-T chr12 Not Cancer Driver No 1 hippie, biogrid 114 0 0 0 0
XPR1 XPR1 Q9UBH6 Xenotropic and polytropic retrovirus receptor 1 chr1 Not Cancer Driver No 1 hippie, biogrid 103 70 15 15 4
ZW10 ZW10 O43264 Centromere/kinetochore protein zw10 homolog chr11 Not Cancer Driver No 1 hippie, biogrid 90 63 11 11 0
ZWILCH ZWILCH Q9H900 Protein zwilch homolog chr15 Not Cancer Driver No 1 hippie, biogrid 67 42 5 5 0