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EFHD2 ,EFHD2 ,Q96C19
  • Number of Interaction partner in intact: 7
  • Number of Interaction partner in biogrid: 21
  • Number of Interaction partner in hippie: 73
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTR2_ENST00000260641 ACTR2 P61160 Actin-related protein 2 chr2 Not Cancer Driver No 1 hippie, biogrid 51 6 2 2 0
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
ARPC2_ENST00000315717 ARPC2 O15144 Actin-related protein 2/3 complex subunit 2 chr2 Not Cancer Driver No 1 hippie, biogrid 40 49 8 8 0
ARPC3 ARPC3 O15145 Actin-related protein 2/3 complex subunit 3 chr12 Not Cancer Driver No 1 hippie, biogrid 17 26 6 6 0
ARPC4-TTLL3 ARPC4-TTLL3 P59998-2 Isoform 2 of Actin-related protein 2/3 complex subunit 4 chr3 Not Cancer Driver No 1 biogrid 64 79 7 7 0
ARPC4_ENST00000397261 ARPC4 P59998 Actin-related protein 2/3 complex subunit 4 chr3 Not Cancer Driver No 1 hippie, biogrid 11 3 0 0 0
ATG16L1 ATG16L1 Q676U5 Autophagy-related protein 16-1 chr2 Not Cancer Driver No 1 hippie 79 239 25 25 1
BICD2_ENST00000375512 BICD2 Q8TD16 Protein bicaudal D homolog 2 chr9 Not Cancer Driver No 1 hippie 115 546 73 73 10
BMI1 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 1 intact, hippie 50 150 30 30 0
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 193 1182 172 172 0
BTF3 BTF3 P20290 Transcription factor BTF3 chr5 Not Cancer Driver No 1 hippie 27 192 24 24 0
CDH1 CDH1 P12830 Cadherin-1 chr16 Census, Compendium Yes 1 hippie 150 400 82 82 5
CENPM CENPM Q9NSP4 Centromere protein M chr22 Not Cancer Driver No 1 hippie, biogrid 12 1 0 0 0
CHMP4A_ENST00000609024 CHMP4A Q9BY43 Charged multivesicular body protein 4a chr14 Not Cancer Driver No 1 hippie 24 204 23 23 0
CHMP4C CHMP4C Q96CF2 Charged multivesicular body protein 4c chr8 Not Cancer Driver No 1 hippie 33 224 31 31 0
COASY_ENST00000421097 COASY Q13057 Bifunctional coenzyme A synthase chr17 Not Cancer Driver No 1 hippie 57 50 4 4 1
CTBP1 CTBP1 Q13363 C-terminal-binding protein 1 chr4 Not Cancer Driver No 1 intact, hippie 42 123 9 9 1
DCAF15 DCAF15 Q66K64 DDB1- and CUL4-associated factor 15 chr19 Not Cancer Driver No 1 hippie 50 173 18 18 0
DCK DCK P27707 Deoxycytidine kinase chr4 Not Cancer Driver No 1 hippie 29 22 4 4 0
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 Not Cancer Driver No 1 hippie 118 61 10 10 2
DTX3_ENST00000337737 DTX3 Q8N9I9 Probable E3 ubiquitin-protein ligase DTX3 chr12 Not Cancer Driver No 1 hippie 58 182 31 31 0
DYNC1LI2 DYNC1LI2 O43237 Cytoplasmic dynein 1 light intermediate chain 2 chr16 Not Cancer Driver No 1 hippie 43 211 14 14 0
EFTUD2 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 132 179 30 30 3
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
ENG ENG P17813 Endoglin chr9 Not Cancer Driver No 1 intact, hippie 60 114 15 15 32
ENO2 ENO2 P09104 Gamma-enolase chr12 Not Cancer Driver No 1 hippie 48 12 2 2 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
FBXO6 FBXO6 Q9NRD1 F-box only protein 6 chr1 Not Cancer Driver No 1 hippie 31 27 3 3 0
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 Census, Compendium Yes 1 hippie 322 230 38 38 0
FCGR2A FCGR2A P12318 Low affinity immunoglobulin gamma Fc region receptor II-a chr1 Not Cancer Driver No 1 hippie, biogrid 64 133 28 28 0
FSD1 FSD1 Q9BTV5 Fibronectin type III and SPRY domain-containing protein 1 chr19 Not Cancer Driver No 2 hippie, biogrid 66 90 17 17 0
FYTTD1 FYTTD1 Q96QD9 UAP56-interacting factor chr3 Not Cancer Driver No 1 hippie, biogrid 51 281 48 48 0
GBF1 GBF1 Q92538 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 chr10 Not Cancer Driver No 1 hippie 216 669 76 76 0
GLRX3 GLRX3 O76003 Glutaredoxin-3 chr10 Not Cancer Driver No 1 hippie 52 24 4 4 0
GMPS GMPS P49915 GMP synthase [glutamine-hydrolyzing] chr3 Census, Compendium Yes 1 hippie 88 76 10 10 0
GSX1 GSX1 Q9H4S2 GS homeobox 1 chr13 Not Cancer Driver No 1 hippie, biogrid 26 137 14 14 0
GTF2E2 GTF2E2 P29084 Transcription initiation factor IIE subunit beta chr8 Not Cancer Driver No 2 intact, hippie, biogrid 34 130 16 16 2
IDH1 IDH1 O75874 Isocitrate dehydrogenase [NADP] cytoplasmic chr2 Census, Compendium Yes 1 hippie 553 37 3 3 0
LIMA1_ENST00000341247 LIMA1 Q9UHB6 LIM domain and actin-binding protein 1 chr12 Not Cancer Driver No 1 hippie 88 687 81 81 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 hippie 519 90 17 17 23
MTAP MTAP Q13126 S-methyl-5'-thioadenosine phosphorylase chr9 Not Cancer Driver No 1 hippie 37 15 0 0 0
MTPN MTPN P58546 Myotrophin chr7 Not Cancer Driver No 1 hippie, biogrid 11 11 3 3 0
MYH10_ENST00000269243 MYH10 P35580 Myosin-10 chr17 Not Cancer Driver No 1 intact, hippie 258 1134 136 136 0
MYH9 MYH9 P35579 Myosin-9 chr22 Census, Compendium Yes 1 intact, hippie 310 1120 160 160 17
MYO18A MYO18A Q92614 Unconventional myosin-XVIIIa chr17 Not Cancer Driver No 1 hippie 268 1237 176 176 0
NMRAL1 NMRAL1 Q9HBL8 NmrA-like family domain-containing protein 1 chr16 Not Cancer Driver No 1 hippie 39 14 3 3 0
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 Not Cancer Driver No 1 hippie 10 82 10 10 0
OR2K2 OR2K2 Q8NGT1 Olfactory receptor 2K2 chr9 Not Cancer Driver No 1 hippie, biogrid 65 0 0 0 0
OR5F1 OR5F1 O95221 Olfactory receptor 5F1 chr11 Not Cancer Driver No 1 hippie, biogrid 146 0 0 0 0
PAN2_ENST00000548043 PAN2 Q504Q3 PAN2-PAN3 deadenylation complex catalytic subunit PAN2 chr12 Not Cancer Driver No 1 hippie 139 78 10 10 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PRKD1_ENST00000616995 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 Census Yes 1 hippie 201 189 33 33 2
PTPN11_ENST00000351677 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 Census, Compendium Yes 1 hippie 129 260 38 38 60
RAD51D_ENST00000394589 RAD51D O75771 DNA repair protein RAD51 homolog 4 chr17 Not Cancer Driver No 1 hippie 34 49 10 10 0
RAE1_ENST00000371242 RAE1 P78406 mRNA export factor RAE1 chr20 Not Cancer Driver No 1 hippie, biogrid 64 73 11 11 0
RBM39 RBM39 Q14498 RNA-binding protein 39 chr20 Compendium Yes 1 hippie 81 228 39 39 0
RCN1 RCN1 Q15293 Reticulocalbin-1 chr11 Not Cancer Driver No 1 hippie 35 158 19 19 0
RDH12_ENST00000267502 RDH12 Q96NR8 Retinol dehydrogenase 12 chr14 Not Cancer Driver No 1 hippie, biogrid 41 0 0 0 10
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 138 608 71 71 1
RHBDD1 RHBDD1 Q8TEB9 Rhomboid-related protein 4 chr2 Not Cancer Driver No 1 hippie 38 69 9 9 0
RHBDF2 RHBDF2 Q6PJF5 Inactive rhomboid protein 2 chr17 Not Cancer Driver No 1 hippie 93 284 36 36 2
RHOD RHOD O00212 Rho-related GTP-binding protein RhoD chr11 Not Cancer Driver No 1 hippie 20 10 0 0 0
SNRNP27 SNRNP27 Q8WVK2 U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein chr2 Not Cancer Driver No 1 hippie, biogrid 20 155 20 20 0
SOX2 SOX2 P48431 Transcription factor SOX-2 chr3 Census Yes 1 hippie 39 312 39 39 0
SSH1 SSH1 Q8WYL5 Protein phosphatase Slingshot homolog 1 chr12 Not Cancer Driver No 1 hippie 129 658 85 85 0
TAS2R41 TAS2R41 P59536 Taste receptor type 2 member 41 chr7 Not Cancer Driver No 1 hippie, biogrid 75 5 3 3 0
TIAF1 MYO18A O95411 Putative TGFB1-induced anti-apoptotic factor 1 chr17 Not Cancer Driver No 1 hippie 16 30 5 5 0
TMOD1_ENST00000395211 TMOD1 P28289 Tropomodulin-1 chr9 Not Cancer Driver No 1 hippie, biogrid 41 195 29 29 0
TYMS TYMS P04818 Thymidylate synthase chr18 Not Cancer Driver No 1 hippie, biogrid 22 41 0 0 0
USP11 USP11 P51784 Ubiquitin carboxyl-terminal hydrolase 11 chrX Not Cancer Driver No 1 hippie 140 210 28 28 0
USP14 USP14 P54578 Ubiquitin carboxyl-terminal hydrolase 14 chr18 Not Cancer Driver No 1 hippie 59 86 6 6 0
USP47 USP47 Q96K76 Ubiquitin carboxyl-terminal hydrolase 47 chr11 Not Cancer Driver No 1 hippie, biogrid 137 425 39 39 0
YWHAE YWHAE P62258 14-3-3 protein epsilon chr17 Census Yes 1 hippie 32 41 3 3 0