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EDEM3 ,EDEM3 ,Q9BZQ6
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 42
  • Number of Interaction partner in hippie: 113
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ALOXE3_ENST00000448843 ALOXE3 Q9BYJ1 Hydroperoxide isomerase ALOXE3 chr17 Not Cancer Driver No 2 hippie, biogrid 108 69 13 13 6
ANGPTL7 ANGPTL7 O43827 Angiopoietin-related protein 7 chr1 Not Cancer Driver No 2 hippie, biogrid 38 33 7 7 0
BTNL2_ENST00000374993 BTNL2 Q9UIR0 Butyrophilin-like protein 2 chr6 Not Cancer Driver No 1 hippie, biogrid 66 82 16 16 0
CA6_ENST00000377443 CA6 P23280 Carbonic anhydrase 6 chr1 Not Cancer Driver No 1 hippie, biogrid 50 56 5 5 0
CALR CALR P27797 Calreticulin chr19 Census Yes 1 hippie 45 245 31 31 0
CANX_ENST00000504734 CANX P27824 Calnexin chr5 Not Cancer Driver No 1 hippie 65 334 38 38 0
CBLN4 CBLN4 Q9NTU7 Cerebellin-4 chr20 Not Cancer Driver No 1 hippie, biogrid 62 20 10 10 0
CD70_ENST00000245903 CD70 P32970 CD70 antigen chr19 Not Cancer Driver No 1 hippie, biogrid 33 11 2 2 0
CDC37 CDC37 Q16543 Hsp90 co-chaperone Cdc37 chr19 Not Cancer Driver No 1 hippie 52 214 31 31 0
CDHR4 CDHR4 A6H8M9 Cadherin-related family member 4 chr3 Not Cancer Driver No 1 hippie, biogrid 54 111 4 4 0
CEACAM8 CEACAM8 P31997 Carcinoembryonic antigen-related cell adhesion molecule 8 chr19 Not Cancer Driver No 1 hippie, biogrid 75 136 23 23 0
CFC1 CFC1 P0CG37 Cryptic protein chr2 Not Cancer Driver No 1 hippie, biogrid 25 68 23 23 1
CHST8_ENST00000434302 CHST8 Q9H2A9 Carbohydrate sulfotransferase 8 chr19 Not Cancer Driver No 1 hippie, biogrid 105 150 23 23 1
CLEC2B CLEC2B Q92478 C-type lectin domain family 2 member B chr12 Not Cancer Driver No 1 hippie, biogrid 28 0 0 0 0
COPA_ENST00000241704 COPA P53621 Coatomer subunit alpha chr1 Not Cancer Driver No 1 hippie 163 157 18 18 4
COPB1_ENST00000439561 COPB1 P53618 Coatomer subunit beta chr11 Not Cancer Driver No 1 hippie 110 95 10 10 1
COPB2 COPB2 P35606 Coatomer subunit beta' chr3 Not Cancer Driver No 1 hippie 111 114 22 22 0
DDOST_ENST00000375048 DDOST P39656 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit chr1 Not Cancer Driver No 1 hippie 34 13 3 3 1
DISC1_ENST00000439617 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 Not Cancer Driver No 1 hippie 132 514 82 82 0
DNAJB9 DNAJB9 Q9UBS3 DnaJ homolog subfamily B member 9 chr7 Not Cancer Driver No 1 hippie, biogrid 30 107 15 15 0
DNAJC10 DNAJC10 Q8IXB1 DnaJ homolog subfamily C member 10 chr2 Not Cancer Driver No 1 hippie 110 36 3 3 0
ECPAS_ENST00000338205 ECPAS Q5VYK3 Proteasome adapter and scaffold protein ECM29 chr9 Not Cancer Driver No 1 hippie 176 240 22 22 0
EDEM1 EDEM1 Q92611 ER degradation-enhancing alpha-mannosidase-like protein 1 chr3 Not Cancer Driver No 1 hippie 54 141 5 5 0
EDEM2 EDEM2 Q9BV94 ER degradation-enhancing alpha-mannosidase-like protein 2 chr20 Not Cancer Driver No 1 hippie 69 54 3 3 0
ELSPBP1 ELSPBP1 Q96BH3 Epididymal sperm-binding protein 1 chr19 Not Cancer Driver No 1 hippie, biogrid 54 0 0 0 0
EMC1 EMC1 Q8N766 ER membrane protein complex subunit 1 chr1 Not Cancer Driver No 1 hippie 107 59 6 6 2
EMC2 EMC2 Q15006 ER membrane protein complex subunit 2 chr8 Not Cancer Driver No 1 hippie 48 29 3 3 0
EMC3 EMC3 Q9P0I2 ER membrane protein complex subunit 3 chr3 Not Cancer Driver No 1 hippie 26 31 6 6 0
ERAP1_ENST00000443439 ERAP1 Q9NZ08 Endoplasmic reticulum aminopeptidase 1 chr5 Not Cancer Driver No 1 hippie 78 70 2 2 0
ERGIC2 ERGIC2 Q96RQ1 Endoplasmic reticulum-Golgi intermediate compartment protein 2 chr12 Not Cancer Driver No 1 hippie 37 25 2 2 0
ERLEC1 ERLEC1 Q96DZ1 Endoplasmic reticulum lectin 1 chr2 Not Cancer Driver No 1 hippie 54 134 17 17 0
ERLIN1 ERLIN1 O75477 Erlin-1 chr10 Not Cancer Driver No 1 hippie 29 46 4 4 1
ERLIN2_ENST00000519638 ERLIN2 O94905 Erlin-2 chr8 Not Cancer Driver No 1 hippie 38 22 3 3 0
ERP29 ERP29 P30040 Endoplasmic reticulum resident protein 29 chr12 Not Cancer Driver No 1 hippie 29 34 5 5 0
ERP44 ERP44 Q9BS26 Endoplasmic reticulum resident protein 44 chr9 Not Cancer Driver No 1 hippie 43 43 3 3 0
FBXO6 FBXO6 Q9NRD1 F-box only protein 6 chr1 Not Cancer Driver No 1 hippie 31 27 3 3 0
FIBIN FIBIN Q8TAL6 Fin bud initiation factor homolog chr11 Not Cancer Driver No 1 hippie, biogrid 42 51 12 12 0
FPR1_ENST00000304748 FPR1 P21462 fMet-Leu-Phe receptor chr19 Not Cancer Driver No 1 hippie, biogrid 99 18 3 3 0
GANAB_ENST00000356638 GANAB Q14697 Neutral alpha-glucosidase AB chr11 Not Cancer Driver No 1 hippie 129 132 20 20 3
GGH GGH Q92820 Gamma-glutamyl hydrolase chr8 Not Cancer Driver No 1 hippie, biogrid 46 5 0 0 0
GP9 GP9 P14770 Platelet glycoprotein IX chr3 Not Cancer Driver No 1 hippie, biogrid 26 0 0 0 7
GPIHBP1 GPIHBP1 Q8IV16 Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 chr8 Not Cancer Driver No 1 hippie, biogrid 26 82 15 15 10
GPR182 GPR182 O15218 G-protein coupled receptor 182 chr12 Not Cancer Driver No 1 hippie, biogrid 49 33 4 4 0
GPR45 GPR45 Q9Y5Y3 Probable G-protein coupled receptor 45 chr2 Not Cancer Driver No 1 hippie, biogrid 97 0 0 0 0
GXYLT1 GXYLT1 Q4G148 Glucoside xylosyltransferase 1 chr12 Not Cancer Driver No 1 hippie, biogrid 58 7 0 0 0
HSP90B1 HSP90B1 P14625 Endoplasmin chr12 Not Cancer Driver No 1 hippie 94 268 35 35 0
HSPA1L HSPA1L P34931 Heat shock 70 kDa protein 1-like chr6 Not Cancer Driver No 1 hippie 119 141 28 28 0
HSPA4L_ENST00000508776 HSPA4L O95757 Heat shock 70 kDa protein 4L chr4 Not Cancer Driver No 1 hippie 105 266 28 28 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 Not Cancer Driver No 1 hippie 73 282 35 35 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 hippie 149 251 52 52 0
HSPB1 HSPB1 P04792 Heat shock protein beta-1 chr7 Not Cancer Driver No 1 hippie 10 118 8 8 20
HSPBP1 HSPBP1 Q9NZL4 Hsp70-binding protein 1 chr19 Not Cancer Driver No 1 hippie 29 130 7 7 0
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 1 hippie 61 82 6 6 2
HSPH1_ENST00000320027 HSPH1 Q92598 Heat shock protein 105 kDa chr13 Not Cancer Driver No 1 hippie 103 323 42 42 0
HYOU1 HYOU1 Q9Y4L1 Hypoxia up-regulated protein 1 chr11 Not Cancer Driver No 1 hippie 132 373 47 47 0
IL5RA_ENST00000256452 IL5RA Q01344 Interleukin-5 receptor subunit alpha chr3 Not Cancer Driver No 1 hippie, biogrid 92 23 5 5 0
ISLR ISLR O14498 Immunoglobulin superfamily containing leucine-rich repeat protein chr15 Not Cancer Driver No 1 hippie, biogrid 83 87 13 13 0
KLK15 KLK15 Q9H2R5 Kallikrein-15 chr19 Not Cancer Driver No 1 hippie, biogrid 94 73 38 38 0
LGI1 LGI1 O95970 Leucine-rich glioma-inactivated protein 1 chr10 Not Cancer Driver No 1 hippie, biogrid 87 3 1 1 17
LLCFC1 LLCFC1 Q96L11-3 Isoform 3 of Sperm-egg fusion protein LLCFC1 chr7 Not Cancer Driver No 1 hippie 42 62 17 17 0
LMAN1 LMAN1 P49257 Protein ERGIC-53 chr18 Not Cancer Driver No 1 hippie 63 222 25 25 1
LRPPRC LRPPRC P42704 Leucine-rich PPR motif-containing protein, mitochondrial chr2 Not Cancer Driver No 1 hippie 131 18 2 2 1
LY9 LY9 Q9HBG7 T-lymphocyte surface antigen Ly-9 chr1 Not Cancer Driver No 1 hippie, biogrid 141 249 49 49 0
LYZL2 LYZL2 Q7Z4W2-2 Isoform 2 of Lysozyme-like protein 2 chr10 Not Cancer Driver No 1 hippie, biogrid 44 2 0 0 0
MAN2A1 MAN2A1 Q16706 Alpha-mannosidase 2 chr5 Not Cancer Driver No 1 hippie 165 83 9 9 0
MFAP4_ENST00000299610 MFAP4 P55083 Microfibril-associated glycoprotein 4 chr17 Not Cancer Driver No 1 hippie, biogrid 35 0 0 0 0
MOGS MOGS Q13724 Mannosyl-oligosaccharide glucosidase chr2 Not Cancer Driver No 1 hippie 105 200 29 29 2
NCR3 NCR3 O14931 Natural cytotoxicity triggering receptor 3 chr6 Not Cancer Driver No 1 hippie, biogrid 26 31 2 2 0
NEDD4L NEDD4L Q96PU5 E3 ubiquitin-protein ligase NEDD4-like chr18 Not Cancer Driver No 1 hippie 126 463 60 60 4
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
NUDCD1 NUDCD1 Q96RS6 NudC domain-containing protein 1 chr8 Not Cancer Driver No 1 hippie 75 38 4 4 0
OS9 OS9 Q13438 Protein OS-9 chr12 Not Cancer Driver No 2 hippie, biogrid 72 451 49 49 0
P2RY10 P2RY10 O00398 Putative P2Y purinoceptor 10 chrX Not Cancer Driver No 1 hippie, biogrid 113 0 0 0 0
P2RY8 P2RY8 Q86VZ1 P2Y purinoceptor 8 chrX Census, Compendium Yes 1 hippie, biogrid 126 23 5 5 0
P4HB P4HB P07237 Protein disulfide-isomerase chr17 Not Cancer Driver No 1 hippie 61 79 15 15 1
PBXIP1 PBXIP1 Q96AQ6 Pre-B-cell leukemia transcription factor-interacting protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 100 605 86 86 0
PDIA3 PDIA3 P30101 Protein disulfide-isomerase A3 chr15 Not Cancer Driver No 1 hippie 57 98 11 11 0
PDIA4 PDIA4 P13667 Protein disulfide-isomerase A4 chr7 Not Cancer Driver No 1 hippie 81 147 22 22 0
PI15 PI15 O43692 Peptidase inhibitor 15 chr8 Not Cancer Driver No 1 hippie, biogrid 87 4 1 1 0
PLD3_ENST00000409735 PLD3 Q8IV08 5'-3' exonuclease PLD3 chr19 Not Cancer Driver No 1 biogrid 70 62 7 7 0
PRG2 PRG2 P13727 Bone marrow proteoglycan chr11 Not Cancer Driver No 1 hippie, biogrid 45 65 15 15 0
PRKCSH_ENST00000589838 PRKCSH P14314 Glucosidase 2 subunit beta chr19 Not Cancer Driver No 1 hippie 68 320 41 41 0
PSMD1 PSMD1 Q99460 26S proteasome non-ATPase regulatory subunit 1 chr2 Not Cancer Driver No 1 hippie 110 201 19 19 0
PSMD5 PSMD5 Q16401 26S proteasome non-ATPase regulatory subunit 5 chr9 Not Cancer Driver No 1 hippie 43 2 1 1 0
RIPK4_ENST00000352483 RIPK4 P57078 Receptor-interacting serine/threonine-protein kinase 4 chr21 Not Cancer Driver No 1 hippie 119 232 34 34 3
RPN1 RPN1 P04843 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 chr3 Census Yes 1 hippie 50 69 3 3 0
RPN2 RPN2 P04844 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 chr20 Not Cancer Driver No 1 hippie 53 26 4 4 0
SAE1 SAE1 Q9UBE0 SUMO-activating enzyme subunit 1 chr19 Not Cancer Driver No 1 hippie 39 90 6 6 0
SDF2L1 SDF2L1 Q9HCN8 Stromal cell-derived factor 2-like protein 1 chr22 Not Cancer Driver No 1 hippie, biogrid 16 130 9 9 0
SEC13_ENST00000350697 SEC13 P55735 Protein SEC13 homolog chr3 Not Cancer Driver No 1 hippie 34 36 6 6 0
SEL1L SEL1L Q9UBV2 Protein sel-1 homolog 1 chr14 Not Cancer Driver No 1 hippie 95 187 18 18 0
SERPINA1 SERPINA1 P01009 Alpha-1-antitrypsin chr14 Not Cancer Driver No 1 hippie 66 38 7 7 0
SERPINH1_ENST00000358171 SERPINH1 P50454 Serpin H1 chr11 Not Cancer Driver No 1 hippie 51 52 6 6 1
SHH SHH Q15465 Sonic hedgehog protein chr7 Not Cancer Driver No 1 hippie 56 139 14 14 81
SHISAL1 SHISAL1 Q3SXP7 Protein shisa-like-1 chr22 Not Cancer Driver No 1 hippie 47 52 20 20 0
SRPRA SRPRA P08240 Signal recognition particle receptor subunit alpha chr11 Not Cancer Driver No 1 hippie 95 232 40 40 0
SSR1 SSR1 P43307 Translocon-associated protein subunit alpha chr6 Not Cancer Driver No 1 hippie 26 114 10 10 0
STT3A_ENST00000529196 STT3A P46977 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A chr11 Not Cancer Driver No 1 hippie 82 27 2 2 1
STT3B STT3B Q8TCJ2 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B chr3 Not Cancer Driver No 1 hippie 60 136 9 9 0
TGOLN2_ENST00000377386 TGOLN2 O43493 Trans-Golgi network integral membrane protein 2 chr2 Not Cancer Driver No 1 hippie 51 399 46 46 0
TM2D3 TM2D3 Q9BRN9 TM2 domain-containing protein 3 chr15 Not Cancer Driver No 1 hippie, biogrid 31 13 3 3 0
TMEM106B TMEM106B Q9NUM4 Transmembrane protein 106B chr7 Not Cancer Driver No 1 hippie 31 56 4 4 1
TMEM87A TMEM87A Q8NBN3 Transmembrane protein 87A chr15 Not Cancer Driver No 1 hippie, biogrid 60 71 10 10 0
TMPRSS2_ENST00000458356 TMPRSS2 O15393 Transmembrane protease serine 2 chr21 Census Yes 1 hippie, biogrid 66 25 5 5 0
TMPRSS4_ENST00000437212 TMPRSS4 Q9NRS4 Transmembrane protease serine 4 chr11 Not Cancer Driver No 1 hippie, biogrid 47 35 4 4 0
TNIK TNIK Q9UKE5 TRAF2 and NCK-interacting protein kinase chr3 Not Cancer Driver No 1 hippie 254 781 156 156 0
TRAP1 TRAP1 Q12931 Heat shock protein 75 kDa, mitochondrial chr16 Not Cancer Driver No 1 hippie 74 110 11 11 0
TRIM33 TRIM33 Q9UPN9 E3 ubiquitin-protein ligase TRIM33 chr1 Census, Compendium Yes 1 hippie 110 617 51 51 0
TRIM66_ENST00000299550 TRIM66 O15016 Tripartite motif-containing protein 66 chr11 Not Cancer Driver No 1 hippie 58 723 32 32 0
TXNDC5 TXNDC5 Q8NBS9 Thioredoxin domain-containing protein 5 chr6 Not Cancer Driver No 1 hippie 47 104 12 12 0
UBA1 UBA1 P22314 Ubiquitin-like modifier-activating enzyme 1 chrX Not Cancer Driver No 1 hippie 117 165 22 22 6
UBA2 UBA2 Q9UBT2 SUMO-activating enzyme subunit 2 chr19 Not Cancer Driver No 1 hippie 84 219 33 33 0
UPK2 UPK2 O00526 Uroplakin-2 chr11 Not Cancer Driver No 1 hippie, biogrid 15 9 1 1 0
VCPIP1 VCPIP1 Q96JH7 Deubiquitinating protein VCPIP1 chr8 Not Cancer Driver No 1 hippie 133 543 61 61 0