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EDA ,EDA ,Q92838
  • Number of Interaction partner in intact: 41
  • Number of Interaction partner in biogrid: 84
  • Number of Interaction partner in hippie: 99
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
AFF4 AFF4 Q9UHB7 AF4/FMR2 family member 4 chr5 Census Yes 2 hippie, biogrid 138 993 121 121 3
AHCYL1 AHCYL1 O43865 S-adenosylhomocysteine hydrolase-like protein 1 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 58 108 10 10 0
ALG5 ALG5 Q9Y673 Dolichyl-phosphate beta-glucosyltransferase chr13 Not Cancer Driver No 3 intact, hippie, biogrid 40 0 0 0 0
ALPL ALPL P05186 Alkaline phosphatase, tissue-nonspecific isozyme chr1 Not Cancer Driver No 1 biogrid 80 184 39 39 113
AP3B1 AP3B1 O00203 AP-3 complex subunit beta-1 chr5 Not Cancer Driver No 3 hippie, biogrid 126 316 31 31 1
AP3B2_ENST00000261722 AP3B2 Q13367 AP-3 complex subunit beta-2 chr15 Not Cancer Driver No 3 intact, hippie, biogrid 145 381 51 51 0
AP3M1 AP3M1 Q9Y2T2 AP-3 complex subunit mu-1 chr10 Not Cancer Driver No 3 hippie, biogrid 45 19 1 1 0
AP3M2_ENST00000174653 AP3M2 P53677 AP-3 complex subunit mu-2 chr8 Not Cancer Driver No 3 intact, hippie, biogrid 56 55 3 3 0
APLNR APLNR P35414 Apelin receptor chr11 Not Cancer Driver No 2 intact, hippie, biogrid 96 29 8 8 0
ATP6V0C ATP6V0C P27449 V-type proton ATPase 16 kDa proteolipid subunit c chr16 Not Cancer Driver No 2 intact, hippie 19 1 0 0 0
C3AR1 C3AR1 Q16581 C3a anaphylatoxin chemotactic receptor chr12 Not Cancer Driver No 2 hippie, biogrid 88 72 16 16 0
C5AR2_ENST00000600626 C5AR2 Q9P296 C5a anaphylatoxin chemotactic receptor 2 chr19 Not Cancer Driver No 2 intact, hippie, biogrid 60 11 3 3 0
CELSR2 CELSR2 Q9HCU4 Cadherin EGF LAG seven-pass G-type receptor 2 chr1 Not Cancer Driver No 1 hippie, biogrid 348 990 115 115 0
CHRNA3 CHRNA3 P32297 Neuronal acetylcholine receptor subunit alpha-3 chr15 Not Cancer Driver No 2 intact, hippie, biogrid 86 11 1 1 0
CHRNA4 CHRNA4 P43681 Neuronal acetylcholine receptor subunit alpha-4 chr20 Not Cancer Driver No 1 hippie, biogrid 144 186 33 33 2
CHRNB1 CHRNB1 P11230 Acetylcholine receptor subunit beta chr17 Not Cancer Driver No 1 hippie, biogrid 62 45 9 9 3
CHRNB4 CHRNB4 P30926 Neuronal acetylcholine receptor subunit beta-4 chr15 Not Cancer Driver No 1 hippie, biogrid 98 30 6 6 0
CHRND CHRND Q07001 Acetylcholine receptor subunit delta chr2 Not Cancer Driver No 1 intact, hippie, biogrid 110 71 19 19 7
CIB1_ENST00000328649 CIB1 Q99828 Calcium and integrin-binding protein 1 chr15 Not Cancer Driver No 1 hippie, biogrid 24 6 1 1 0
CIZ1_ENST00000634901 CIZ1 Q9ULV3 Cip1-interacting zinc finger protein chr9 Not Cancer Driver No 3 intact, hippie, biogrid 93 708 83 83 0
CRTAP CRTAP O75718 Cartilage-associated protein chr3 Not Cancer Driver No 3 intact, hippie, biogrid 29 0 0 0 3
CTXN3_ENST00000395322 CTXN3 Q4LDR2 Cortexin-3 chr5 Not Cancer Driver No 1 hippie 24 7 1 1 0
CWC22 CWC22 Q9HCG8 Pre-mRNA-splicing factor CWC22 homolog chr2 Not Cancer Driver No 3 intact, hippie, biogrid 104 494 56 56 0
CWC27 CWC27 Q6UX04 Spliceosome-associated protein CWC27 homolog chr5 Not Cancer Driver No 3 hippie, biogrid 60 345 43 43 0
CXXC1_ENST00000285106 CXXC1 Q9P0U4 CXXC-type zinc finger protein 1 chr18 Not Cancer Driver No 3 intact, hippie, biogrid 115 366 65 65 0
CYB561_ENST00000392976 CYB561 P49447 Transmembrane ascorbate-dependent reductase CYB561 chr17 Not Cancer Driver No 1 hippie 28 6 0 0 1
DDX39A DDX39A O00148 ATP-dependent RNA helicase DDX39A chr19 Not Cancer Driver No 1 hippie, biogrid 44 37 2 2 0
DOLK DOLK Q9UPQ8 Dolichol kinase chr9 Not Cancer Driver No 1 hippie 49 12 1 1 2
EDA EDA Q92838 Ectodysplasin-A chrX Not Cancer Driver No 2 intact, hippie 73 243 43 43 71
EDA2R_ENST00000451436 EDA2R Q9HAV5 Tumor necrosis factor receptor superfamily member 27 chrX Not Cancer Driver No 1 hippie 52 72 11 11 0
EDAR EDAR Q9UNE0 Tumor necrosis factor receptor superfamily member EDAR chr2 Not Cancer Driver No 1 hippie 81 116 20 20 18
EIF4A3 EIF4A3 P38919 Eukaryotic initiation factor 4A-III chr17 Not Cancer Driver No 1 hippie, biogrid 50 57 6 6 1
EMP1 EMP1 P54849 Epithelial membrane protein 1 chr12 Not Cancer Driver No 1 hippie 18 0 0 0 0
EMP3_ENST00000597279 EMP3 P54852 Epithelial membrane protein 3 chr19 Not Cancer Driver No 2 intact, hippie 18 0 0 0 0
EVA1C EVA1C P58658 Protein eva-1 homolog C chr21 Not Cancer Driver No 1 intact, hippie, biogrid 47 60 2 2 0
FAM189B FAM189B P81408 Protein FAM189B chr1 Not Cancer Driver No 1 intact, hippie, biogrid 56 302 21 21 0
FSHR FSHR P23945 Follicle-stimulating hormone receptor chr2 Not Cancer Driver No 1 hippie, biogrid 226 28 11 11 16
FURIN_ENST00000610579 FURIN P09958 Furin chr15 Not Cancer Driver No 1 hippie 93 283 35 35 0
GABRA3_ENST00000535043 GABRA3 P34903 Gamma-aminobutyric acid receptor subunit alpha-3 chrX Not Cancer Driver No 1 intact, hippie, biogrid 136 47 10 10 0
GDPD5_ENST00000529721 GDPD5 Q8WTR4 Glycerophosphodiester phosphodiesterase domain-containing protein 5 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 74 65 11 11 0
GIMAP5 GIMAP5 Q96F15 GTPase IMAP family member 5 chr7 Not Cancer Driver No 1 hippie 78 20 2 2 0
GPM6A_ENST00000393658 GPM6A P51674 Neuronal membrane glycoprotein M6-a chr4 Not Cancer Driver No 3 intact, hippie, biogrid 83 15 5 5 0
GPR17 GPR17 Q13304 Uracil nucleotide/cysteinyl leukotriene receptor chr2 Not Cancer Driver No 1 hippie, biogrid 57 16 4 4 0
GPR21 GPR21 Q99679 Probable G-protein coupled receptor 21 chr9 Not Cancer Driver No 2 intact, hippie, biogrid 39 2 0 0 0
HLA-DQA1 HLA-DQA1 A0A173ADG5 HLA class II histocompatibility antigen DQ alpha chain chr6 Not Cancer Driver No 1 hippie, biogrid 29 5 0 0 0
HTR3C HTR3C Q8WXA8 5-hydroxytryptamine receptor 3C chr3 Not Cancer Driver No 2 intact, hippie, biogrid 82 35 7 7 0
IL9R IL9R Q01113 Interleukin-9 receptor chrX Not Cancer Driver No 3 intact, hippie, biogrid 96 78 18 18 0
IPO7 IPO7 O95373 Importin-7 chr11 Not Cancer Driver No 1 hippie, biogrid 138 202 30 30 0
JPH1 JPH1 Q9HDC5 Junctophilin-1 chr8 Not Cancer Driver No 1 hippie, biogrid 131 421 89 89 0
KBTBD7 KBTBD7 Q8WVZ9 Kelch repeat and BTB domain-containing protein 7 chr13 Not Cancer Driver No 3 intact, hippie, biogrid 92 105 6 6 0
KCMF1 KCMF1 Q9P0J7 E3 ubiquitin-protein ligase KCMF1 chr2 Not Cancer Driver No 1 hippie, biogrid 48 270 36 36 0
KCNJ10 KCNJ10 P78508 ATP-sensitive inward rectifier potassium channel 10 chr1 Not Cancer Driver No 1 hippie, biogrid 78 28 10 10 8
LEPROTL1_ENST00000321250 LEPROTL1 O95214 Leptin receptor overlapping transcript-like 1 chr8 Census Yes 1 hippie 8 0 0 0 0
LNPK_ENST00000272748 LNPK Q9C0E8 Endoplasmic reticulum junction formation protein lunapark chr2 Not Cancer Driver No 1 hippie 62 257 43 43 0
LPAR3_ENST00000370611 LPAR3 Q9UBY5 Lysophosphatidic acid receptor 3 chr1 Not Cancer Driver No 1 hippie 65 9 0 0 0
MAL MAL P21145 Myelin and lymphocyte protein chr2 Not Cancer Driver No 2 intact, hippie 21 0 0 0 0
MLLT3 MLLT3 P42568 Protein AF-9 chr9 Census, Compendium Yes 3 hippie, biogrid 69 414 58 58 0
MMP2 MMP2 P08253 72 kDa type IV collagenase chr16 Not Cancer Driver No 2 intact, hippie, biogrid 123 29 6 6 2
MS4A13 MS4A13 Q5J8X5 Membrane-spanning 4-domains subfamily A member 13 chr11 Not Cancer Driver No 1 hippie 37 9 4 4 0
NAF1 NAF1 Q96HR8 H/ACA ribonucleoprotein complex non-core subunit NAF1 chr4 Not Cancer Driver No 3 intact, hippie, biogrid 61 386 44 44 0
NIPAL3 NIPAL3 Q6P499 NIPA-like protein 3 chr1 Not Cancer Driver No 1 hippie 54 20 3 3 0
NOC2L NOC2L Q9Y3T9 Nucleolar complex protein 2 homolog chr1 Not Cancer Driver No 1 hippie, biogrid 77 281 31 31 0
OSBPL8 OSBPL8 Q9BZF1 Oxysterol-binding protein-related protein 8 chr12 Not Cancer Driver No 3 intact, hippie, biogrid 105 401 37 37 0
OSTC_ENST00000361564 OSTC Q9NRP0 Oligosaccharyltransferase complex subunit OSTC chr4 Not Cancer Driver No 1 hippie 14 0 0 0 0
P3H1_ENST00000296388 P3H1 Q32P28 Prolyl 3-hydroxylase 1 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 91 177 18 18 0
P3H2 P3H2 Q8IVL5 Prolyl 3-hydroxylase 2 chr3 Not Cancer Driver No 2 intact, hippie, biogrid 131 160 24 24 1
P4HA1_ENST00000394890 P4HA1 P13674 Prolyl 4-hydroxylase subunit alpha-1 chr10 Not Cancer Driver No 1 hippie, biogrid 65 54 8 8 0
PCDHAC2 PCDHAC2 Q9Y5I4 Protocadherin alpha-C2 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 215 416 94 94 0
PCDHB1 PCDHB1 Q9Y5F3 Protocadherin beta-1 chr5 Not Cancer Driver No 1 hippie, biogrid 215 159 34 34 0
PLN PLN P26678 Cardiac phospholamban chr6 Not Cancer Driver No 2 intact, hippie 10 0 0 0 3
PMP22_ENST00000612492 PMP22 Q01453 Peripheral myelin protein 22 chr17 Not Cancer Driver No 1 hippie 20 0 0 0 37
PNN PNN Q9H307 Pinin chr14 Not Cancer Driver No 3 hippie, biogrid 94 700 90 90 0
PTGIR PTGIR P43119 Prostacyclin receptor chr19 Not Cancer Driver No 2 hippie, biogrid 40 47 4 4 0
RABL3 RABL3 Q5HYI8 Rab-like protein 3 chr3 Not Cancer Driver No 1 hippie, biogrid 37 1 0 0 1
RASSF8_ENST00000541490 RASSF8 Q8NHQ8 Ras association domain-containing protein 8 chr12 Not Cancer Driver No 1 hippie, biogrid 47 206 19 19 0
RNPS1_ENST00000301730 RNPS1 Q15287 RNA-binding protein with serine-rich domain 1 chr16 Not Cancer Driver No 1 hippie, biogrid 30 305 30 30 0
SEC22A_ENST00000492595 SEC22A Q96IW7 Vesicle-trafficking protein SEC22a chr3 Not Cancer Driver No 1 hippie 35 0 0 0 0
SETD1A SETD1A O15047 Histone-lysine N-methyltransferase SETD1A chr16 Not Cancer Driver No 3 hippie, biogrid 223 1327 188 188 5
SIDT2_ENST00000620360 SIDT2 Q8NBJ9 SID1 transmembrane family member 2 chr11 Not Cancer Driver No 1 hippie, biogrid 113 23 6 6 0
SIN3A_ENST00000360439 SIN3A Q96ST3 Paired amphipathic helix protein Sin3a chr15 Compendium Yes 1 hippie, biogrid 172 617 73 73 0
SLC38A7 SLC38A7 Q9NVC3 Putative sodium-coupled neutral amino acid transporter 7 chr16 Not Cancer Driver No 1 hippie 50 10 0 0 0
SLC39A4 SLC39A4 Q6P5W5 Zinc transporter ZIP4 chr8 Not Cancer Driver No 3 intact, hippie, biogrid 77 116 11 11 9
SLC39A8 SLC39A8 Q9C0K1 Metal cation symporter ZIP8 chr4 Not Cancer Driver No 1 intact, hippie, biogrid 45 22 2 2 5
SLC5A4 SLC5A4 Q9NY91 Solute carrier family 5 member 4 chr22 Not Cancer Driver No 1 hippie, biogrid 103 48 6 6 0
SLCO6A1_ENST00000379807 SLCO6A1 Q86UG4 Solute carrier organic anion transporter family member 6A1 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 224 67 38 38 0
SRRM2 SRRM2 Q9UQ35 Serine/arginine repetitive matrix protein 2 chr16 Not Cancer Driver No 2 hippie, biogrid 433 2748 431 431 0
TAS1R2 TAS1R2 Q8TE23 Taste receptor type 1 member 2 chr1 Not Cancer Driver No 1 hippie, biogrid 206 29 10 10 0
TEX264_ENST00000416589 TEX264 Q9Y6I9 Testis-expressed protein 264 chr3 Not Cancer Driver No 3 intact, hippie, biogrid 40 107 11 11 0
TMEM169_ENST00000437356 TMEM169 Q96HH4 Transmembrane protein 169 chr2 Not Cancer Driver No 1 hippie, biogrid 57 115 25 25 0
TMEM42 TMEM42 Q69YG0 Transmembrane protein 42 chr3 Not Cancer Driver No 1 hippie 8 20 0 0 0
TMEM50B TMEM50B P56557 Transmembrane protein 50B chr21 Not Cancer Driver No 1 hippie 19 0 0 0 0
TMEM60 TMEM60 Q9H2L4 Transmembrane protein 60 chr7 Not Cancer Driver No 1 hippie 13 0 0 0 0
TMUB1_ENST00000297533 TMUB1 Q9BVT8 Transmembrane and ubiquitin-like domain-containing protein 1 chr7 Not Cancer Driver No 1 hippie, biogrid 19 128 10 10 0
TNRC18 TNRC18 O15417 Trinucleotide repeat-containing gene 18 protein chr7 Not Cancer Driver No 3 intact, hippie, biogrid 310 2580 271 271 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
UBR4 UBR4 Q5T4S7 E3 ubiquitin-protein ligase UBR4 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 565 1066 119 119 0
UBTF UBTF P17480 Nucleolar transcription factor 1 chr17 Not Cancer Driver No 3 intact, hippie, biogrid 100 567 77 77 1
VMA21 VMA21 Q3ZAQ7 Vacuolar ATPase assembly integral membrane protein VMA21 chrX Not Cancer Driver No 3 intact, hippie, biogrid 18 7 1 1 0
ZACN ZACN Q401N2 Zinc-activated ligand-gated ion channel chr17 Not Cancer Driver No 3 hippie, biogrid 46 48 6 6 0
ZDHHC12 ZDHHC12 Q96GR4 Palmitoyltransferase ZDHHC12 chr9 Not Cancer Driver No 1 hippie, biogrid 23 13 1 1 0