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ECM1_ENST00000369047 ,ECM1 ,Q16610
  • Uniprot Accession= Q16610
  • Ensembl Transcript= ENST00000369047.8
  • Uniprot Name= ECM1
  • Name= Extracellular matrix protein 1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 19
  • Number of Interaction partner in biogrid: 61
  • Number of Interaction partner in hippie: 115
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
A1CF_ENST00000373993 A1CF Q9NQ94 APOBEC1 complementation factor chr10 Census Yes 1 hippie 150 63 20 20 0
ACTN3_ENST00000513398 ACTN3 Q08043 Alpha-actinin-3 chr11 Not Cancer Driver No 1 hippie 123 135 13 13 0
AHDC1_ENST00000644989 AHDC1 Q5TGY3 AT-hook DNA-binding motif-containing protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 150 1466 145 145 0
ALDH3A1_ENST00000444455 ALDH3A1 P30838 Aldehyde dehydrogenase, dimeric NADP-preferring chr17 Not Cancer Driver No 1 hippie, biogrid 73 36 7 7 0
AMTN AMTN Q6UX39 Amelotin chr4 Not Cancer Driver No 1 hippie, biogrid 39 126 28 28 0
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
ATN1_ENST00000396684 ATN1 P54259 Atrophin-1 chr12 Not Cancer Driver No 1 hippie 141 1176 139 139 6
ATP23 ATP23 Q9Y6H3 Mitochondrial inner membrane protease ATP23 homolog chr12 Not Cancer Driver No 1 hippie 26 25 3 3 0
ATP6AP2 ATP6AP2 O75787 Renin receptor chrX Not Cancer Driver No 1 hippie, biogrid 56 0 0 0 2
BCAS2 BCAS2 O75934 Pre-mRNA-splicing factor SPF27 chr1 Not Cancer Driver No 1 hippie 30 55 5 5 0
BNIP3L BNIP3L O60238 BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like chr8 Not Cancer Driver No 1 hippie 16 175 14 14 0
BUB1B BUB1B O60566 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta chr15 Census Yes 1 hippie, biogrid 96 480 35 35 7
C1orf109 C1orf109 Q9NX04 Uncharacterized protein C1orf109 chr1 Not Cancer Driver No 1 hippie 17 0 0 0 0
C22orf39_ENST00000611555 C22orf39 Q6P5X5 UPF0545 protein C22orf39 chr22 Not Cancer Driver No 1 hippie, biogrid 8 47 4 4 0
CA8 CA8 P35219 Carbonic anhydrase-related protein chr8 Not Cancer Driver No 2 hippie, biogrid 56 32 2 2 1
CCDC51 CCDC51 Q96ER9 Mitochondrial potassium channel chr3 Not Cancer Driver No 2 intact, hippie, biogrid 51 137 21 21 0
CCNC CCNC P24863 Cyclin-C chr6 Census Yes 1 hippie, biogrid 32 33 3 3 0
CD274 CD274 Q9NZQ7 Programmed cell death 1 ligand 1 chr9 Census Yes 1 hippie 29 54 9 9 0
CDK10 CDK10 Q15131 Cyclin-dependent kinase 10 chr16 Not Cancer Driver No 1 hippie, biogrid 42 30 4 4 0
CDKL3 CDKL3 Q8IVW4 Cyclin-dependent kinase-like 3 chr5 Not Cancer Driver No 1 hippie, biogrid 68 278 40 40 0
CFAP298 CFAP298 P57076 Cilia- and flagella-associated protein 298 chr21 Not Cancer Driver No 2 intact, hippie 26 111 10 10 0
CFI_ENST00000394634 CFI P05156 Complement factor I chr4 Not Cancer Driver No 2 intact, hippie, biogrid 97 4 0 0 13
COL6A1 COL6A1 P12109 Collagen alpha-1(VI) chain chr21 Not Cancer Driver No 1 hippie, biogrid 145 434 61 61 12
COX20_ENST00000411948 COX20 Q5RI15 Cytochrome c oxidase assembly protein COX20, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie, biogrid 12 31 4 4 1
CPTP CPTP Q5TA50 Ceramide-1-phosphate transfer protein chr1 Not Cancer Driver No 1 hippie 16 4 0 0 0
CSNK1D CSNK1D P48730 Casein kinase I isoform delta chr17 Not Cancer Driver No 1 hippie, biogrid 59 132 16 16 2
CTU1 CTU1 Q7Z7A3 Cytoplasmic tRNA 2-thiolation protein 1 chr19 Not Cancer Driver No 1 hippie, biogrid 12 60 1 1 0
CTU2_ENST00000453996 CTU2 Q2VPK5 Cytoplasmic tRNA 2-thiolation protein 2 chr16 Not Cancer Driver No 1 hippie, biogrid 46 137 11 11 0
CUL1_ENST00000602748 CUL1 Q13616 Cullin-1 chr7 Not Cancer Driver No 1 intact, hippie, biogrid 151 65 9 9 0
CYLD CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 Census, Compendium Yes 1 hippie 116 213 31 31 3
CYSRT1 CYSRT1 B8A4K4 Cysteine-rich tail protein 1 chr9 Not Cancer Driver No 1 hippie 9 142 5 5 0
DDIAS DDIAS Q8IXT1 DNA damage-induced apoptosis suppressor protein chr11 Not Cancer Driver No 1 hippie 125 370 59 59 0
DDX39B_ENST00000458640 DDX39B Q13838 Spliceosome RNA helicase DDX39B chr6 Not Cancer Driver No 1 hippie 49 34 8 8 0
DPPA4 DPPA4 Q7L190 Developmental pluripotency-associated protein 4 chr3 Not Cancer Driver No 1 intact, hippie, biogrid 94 180 46 46 0
DTX2 DTX2 Q86UW9 Probable E3 ubiquitin-protein ligase DTX2 chr7 Not Cancer Driver No 1 hippie 84 292 42 42 0
DYRK3 DYRK3 O43781 Dual specificity tyrosine-phosphorylation-regulated kinase 3 chr1 Not Cancer Driver No 1 hippie, biogrid 87 193 20 20 0
E2F6 E2F6 O75461 Transcription factor E2F6 chr2 Not Cancer Driver No 1 hippie, biogrid 20 105 10 10 0
EEF1A2 EEF1A2 Q05639 Elongation factor 1-alpha 2 chr20 Not Cancer Driver No 1 hippie 74 121 17 17 3
ENKD1 ENKD1 Q9H0I2 Enkurin domain-containing protein 1 chr16 Not Cancer Driver No 1 hippie 40 307 34 34 0
ERCC3 ERCC3 P19447 General transcription and DNA repair factor IIH helicase subunit XPB chr2 Census, Compendium Yes 1 hippie, biogrid 92 208 22 22 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
FASLG FASLG P48023 Tumor necrosis factor ligand superfamily member 6 chr1 Not Cancer Driver No 1 hippie 65 94 18 18 1
FASTK FASTK Q14296 Fas-activated serine/threonine kinase chr7 Not Cancer Driver No 1 hippie, biogrid 65 143 12 12 0
FBLN1 FBLN1 P23142 Fibulin-1 chr22 Compendium Yes 1 hippie 122 22 3 3 0
FKBP6 FKBP6 O75344 Inactive peptidyl-prolyl cis-trans isomerase FKBP6 chr7 Not Cancer Driver No 1 hippie 75 17 1 1 0
FN1 FN1 P02751 Fibronectin chr2 Compendium Yes 1 hippie, biogrid 394 1243 185 185 8
FRMD1 FRMD1 Q8N878 FERM domain-containing protein 1 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 82 259 36 36 0
FRS3_ENST00000259748 FRS3 O43559 Fibroblast growth factor receptor substrate 3 chr6 Not Cancer Driver No 1 hippie 77 388 58 58 0
FTH1_ENST00000620041 FTH1 P02794 Ferritin heavy chain chr11 Not Cancer Driver No 1 hippie, biogrid 20 57 7 7 0
FXR1 FXR1 P51114 Fragile X mental retardation syndrome-related protein 1 chr3 Not Cancer Driver No 1 hippie 88 312 53 53 0
GBP2 GBP2 P32456 Guanylate-binding protein 2 chr1 Not Cancer Driver No 1 intact 75 134 15 15 0
GCM2 GCM2 O75603 Chorion-specific transcription factor GCMb chr6 Not Cancer Driver No 1 hippie 91 272 50 50 7
GCN1 GCN1 Q92616 eIF-2-alpha kinase activator GCN1 chr12 Not Cancer Driver No 1 intact 327 117 16 16 0
GLYR1 GLYR1 Q49A26 Putative oxidoreductase GLYR1 chr16 Not Cancer Driver No 1 intact, hippie, biogrid 87 201 27 27 0
GMCL1 GMCL1 Q96IK5 Germ cell-less protein-like 1 chr2 Not Cancer Driver No 3 intact, hippie, biogrid 33 80 2 2 0
GNE_ENST00000539815 GNE Q9Y223 Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase chr9 Not Cancer Driver No 1 hippie 83 15 2 2 36
GPANK1_ENST00000375896 GPANK1 O95872 G patch domain and ankyrin repeat-containing protein 1 chr6 Not Cancer Driver No 1 hippie 35 297 26 26 0
GRN GRN P28799 Progranulin chr17 Not Cancer Driver No 1 hippie 76 29 6 6 1
HECW2_ENST00000644256 HECW2 Q9P2P5 E3 ubiquitin-protein ligase HECW2 chr2 Not Cancer Driver No 1 hippie 348 845 195 195 4
HIBADH HIBADH P31937 3-hydroxyisobutyrate dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 28 7 2 2 0
HOXC8 HOXC8 P31273 Homeobox protein Hox-C8 chr12 Not Cancer Driver No 1 hippie 38 139 19 19 0
HSPG2 HSPG2 P98160 Basement membrane-specific heparan sulfate proteoglycan core protein chr1 Compendium Yes 1 hippie 506 1709 194 194 1
IL2RB IL2RB P14784 Interleukin-2 receptor subunit beta chr22 Not Cancer Driver No 1 hippie 81 182 33 33 1
IRAK3 IRAK3 Q9Y616 Interleukin-1 receptor-associated kinase 3 chr12 Not Cancer Driver No 1 hippie 103 79 14 14 0
ITGB4 ITGB4 P16144 Integrin beta-4 chr17 Not Cancer Driver No 1 hippie 248 753 86 86 14
KLHL38 KLHL38 Q2WGJ6 Kelch-like protein 38 chr8 Not Cancer Driver No 1 hippie 114 3 2 2 0
KRTAP5-3 KRTAP5-3 Q6L8H2 Keratin-associated protein 5-3 chr11 Not Cancer Driver No 1 hippie 50 0 0 0 0
KRTAP9-3 KRTAP9-3 Q9BYQ3 Keratin-associated protein 9-3 chr17 Not Cancer Driver No 1 hippie 31 0 0 0 0
LCE2A LCE2A Q5TA79 Late cornified envelope protein 2A chr1 Not Cancer Driver No 1 hippie 32 0 0 0 0
LIN7A LIN7A O14910 Protein lin-7 homolog A chr12 Not Cancer Driver No 1 hippie 76 127 29 29 0
LMO4 LMO4 P61968 LIM domain transcription factor LMO4 chr1 Not Cancer Driver No 1 hippie 30 11 1 1 0
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 Not Cancer Driver No 1 hippie, biogrid 104 333 66 66 6
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 Census, Compendium Yes 1 hippie, biogrid 62 2 0 0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 Not Cancer Driver No 1 hippie, biogrid 38 49 5 5 0
MCL1 MCL1 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 chr1 Not Cancer Driver No 2 hippie, biogrid 30 203 21 21 0
MKRN3 MKRN3 Q13064 Probable E3 ubiquitin-protein ligase makorin-3 chr15 Not Cancer Driver No 1 hippie 197 201 99 99 4
MMRN1 MMRN1 Q13201 Multimerin-1 chr4 Not Cancer Driver No 2 intact, hippie, biogrid 241 373 75 75 0
MRPL39_ENST00000352957 MRPL39 Q9NYK5 39S ribosomal protein L39, mitochondrial chr21 Not Cancer Driver No 1 hippie, biogrid 41 38 6 6 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
NFX1 NFX1 Q12986 Transcriptional repressor NF-X1 chr9 Not Cancer Driver No 1 hippie 121 491 46 46 0
NHLRC2 NHLRC2 Q8NBF2 NHL repeat-containing protein 2 chr10 Not Cancer Driver No 1 hippie 74 103 12 12 0
NPPA NPPA P01160 Natriuretic peptides A chr1 Not Cancer Driver No 2 intact, hippie, biogrid 32 71 14 14 1
NSG2 NSG2 Q9Y328 Neuronal vesicle trafficking-associated protein 2 chr5 Not Cancer Driver No 1 hippie 34 43 9 9 0
PAK2 PAK2 Q13177 Serine/threonine-protein kinase PAK 2 chr3 Compendium Yes 1 hippie, biogrid 89 242 49 49 0
PI4K2A PI4K2A Q9BTU6 Phosphatidylinositol 4-kinase type 2-alpha chr10 Not Cancer Driver No 1 hippie, biogrid 43 129 6 6 0
PI4KA PI4KA P42356 Phosphatidylinositol 4-kinase alpha chr22 Not Cancer Driver No 1 hippie, biogrid 267 142 11 11 1
PLCZ1 PLCZ1 Q86YW0 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 chr12 Not Cancer Driver No 1 intact, hippie, biogrid 151 37 20 20 1
PRKAG1_ENST00000548065 PRKAG1 P54619 5'-AMP-activated protein kinase subunit gamma-1 chr12 Not Cancer Driver No 1 hippie, biogrid 35 25 2 2 0
PRKAR2B PRKAR2B P31323 cAMP-dependent protein kinase type II-beta regulatory subunit chr7 Not Cancer Driver No 1 hippie 60 125 4 4 0
RBFOX1_ENST00000550418 RBFOX1 Q9NWB1 RNA binding protein fox-1 homolog 1 chr16 Compendium Yes 1 intact, hippie, biogrid 179 181 89 89 0
RERE RERE Q9P2R6 Arginine-glutamic acid dipeptide repeats protein chr1 Not Cancer Driver No 1 hippie 196 1297 167 167 0
RNASEH1 RNASEH1 O60930 Ribonuclease H1 chr2 Not Cancer Driver No 1 hippie, biogrid 33 124 20 20 2
RNGTT RNGTT O60942 mRNA-capping enzyme chr6 Not Cancer Driver No 1 hippie 69 112 12 12 0
RNPC3 RNPC3 Q96LT9 RNA-binding region-containing protein 3 chr1 Not Cancer Driver No 1 hippie, biogrid 20 314 12 12 1
SAMD11 SAMD11 Q96NU1 Sterile alpha motif domain-containing protein 11 chr1 Not Cancer Driver No 1 hippie 60 576 40 40 0
SARAF SARAF Q96BY9 Store-operated calcium entry-associated regulatory factor chr8 Not Cancer Driver No 1 hippie, biogrid 32 73 8 8 0
SGTB SGTB Q96EQ0 Small glutamine-rich tetratricopeptide repeat-containing protein beta chr5 Not Cancer Driver No 1 hippie 28 114 10 10 0
SH2D3A SH2D3A Q9BRG2 SH2 domain-containing protein 3A chr19 Not Cancer Driver No 1 hippie, biogrid 68 305 40 40 0
SLC35F2 SLC35F2 Q8IXU6 Solute carrier family 35 member F2 chr11 Not Cancer Driver No 1 hippie, biogrid 53 12 0 0 0
SLC9A5 SLC9A5 Q14940 Sodium/hydrogen exchanger 5 chr16 Not Cancer Driver No 1 hippie, biogrid 118 307 35 35 0
SNRPC SNRPC P09234 U1 small nuclear ribonucleoprotein C chr6 Not Cancer Driver No 1 hippie 26 143 26 26 0
SNTG1 SNTG1 Q9NSN8 Gamma-1-syntrophin chr8 Not Cancer Driver No 1 hippie, biogrid 204 3 1 1 0
SRPK1 SRPK1 Q96SB4 SRSF protein kinase 1 chr6 Not Cancer Driver No 1 hippie 73 329 32 32 0
SRRT SRRT Q9BXP5 Serrate RNA effector molecule homolog chr7 Not Cancer Driver No 1 hippie, biogrid 146 595 108 108 0
STX17_ENST00000534052 STX17 P56962 Syntaxin-17 chr9 Not Cancer Driver No 1 hippie, biogrid 27 81 4 4 0
TBC1D22B TBC1D22B Q9NU19 TBC1 domain family member 22B chr6 Not Cancer Driver No 2 intact, hippie, biogrid 55 205 27 27 0
TEFM TEFM Q96QE5 Transcription elongation factor, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 37 26 5 5 0
TGM2 TGM2 P21980 Protein-glutamine gamma-glutamyltransferase 2 chr20 Not Cancer Driver No 1 hippie, biogrid 123 107 26 26 0
TRIM68 TRIM68 Q6AZZ1 E3 ubiquitin-protein ligase TRIM68 chr11 Not Cancer Driver No 1 hippie, biogrid 74 37 7 7 0
UBQLN1 UBQLN1 Q9UMX0 Ubiquilin-1 chr9 Not Cancer Driver No 1 hippie 64 543 58 58 0
UBQLN2 UBQLN2 Q9UHD9 Ubiquilin-2 chrX Not Cancer Driver No 1 hippie 82 581 79 79 8
VHL VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 Census, Compendium Yes 1 hippie, biogrid 142 117 36 36 133
XRN1 XRN1 Q8IZH2 5'-3' exoribonuclease 1 chr3 Not Cancer Driver No 1 intact 213 577 65 65 0
YAF2_ENST00000534854 YAF2 Q8IY57 YY1-associated factor 2 chr12 Not Cancer Driver No 1 hippie, biogrid 27 166 27 27 0
YES1_ENST00000314574 YES1 P07947 Tyrosine-protein kinase Yes chr18 Not Cancer Driver No 1 hippie, biogrid 65 62 10 10 0
ZDHHC19 ZDHHC19 Q8WVZ1 Palmitoyltransferase ZDHHC19 chr3 Not Cancer Driver No 1 hippie, biogrid 48 35 10 10 0
ZIC1 ZIC1 Q15915 Zinc finger protein ZIC 1 chr3 Not Cancer Driver No 2 intact, hippie, biogrid 187 246 113 113 1
ZSCAN12_ENST00000396827 ZSCAN12 O43309-2 Isoform 2 of Zinc finger and SCAN domain-containing protein 12 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 44 237 25 25 0