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ECE1 ,ECE1 ,P42892
  • Uniprot Accession= P42892
  • Ensembl Transcript= ENST00000374893.10
  • Uniprot Name= ECE1
  • Name= Endothelin-converting enzyme 1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 12
  • Number of Interaction partner in biogrid: 70
  • Number of Interaction partner in hippie: 91
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AGT AGT P01019 Angiotensinogen chr1 Not Cancer Driver No 1 hippie 85 33 10 10 1
ANKFY1_ENST00000341657 ANKFY1 Q9P2R3 Rabankyrin-5 chr17 Not Cancer Driver No 1 hippie, biogrid 109 185 29 29 0
AQP3 AQP3 Q92482 Aquaporin-3 chr9 Not Cancer Driver No 1 hippie, biogrid 34 12 0 0 0
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 Not Cancer Driver No 1 hippie, biogrid 18 5 0 0 0
BICD2_ENST00000375512 BICD2 Q8TD16 Protein bicaudal D homolog 2 chr9 Not Cancer Driver No 1 hippie 115 546 73 73 10
BRICD5_ENST00000562360 BRICD5 Q6PL45 BRICHOS domain-containing protein 5 chr16 Not Cancer Driver No 1 hippie, biogrid 43 82 11 11 0
CALCA_ENST00000361010 CALCA P06881 Calcitonin gene-related peptide 1 chr11 Not Cancer Driver No 1 hippie 25 44 11 11 0
CANX_ENST00000504734 CANX P27824 Calnexin chr5 Not Cancer Driver No 1 intact, hippie 65 334 38 38 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 Not Cancer Driver No 1 hippie, biogrid 30 2 0 0 0
CD1B CD1B P29016 T-cell surface glycoprotein CD1b chr1 Not Cancer Driver No 1 hippie, biogrid 97 7 0 0 0
CEACAM8 CEACAM8 P31997 Carcinoembryonic antigen-related cell adhesion molecule 8 chr19 Not Cancer Driver No 1 hippie, biogrid 75 136 23 23 0
CLEC12B CLEC12B Q2HXU8 C-type lectin domain family 12 member B chr12 Not Cancer Driver No 1 hippie, biogrid 34 57 8 8 0
CLEC2B CLEC2B Q92478 C-type lectin domain family 2 member B chr12 Not Cancer Driver No 1 hippie, biogrid 28 0 0 0 0
CLGN_ENST00000414773 CLGN O14967 Calmegin chr4 Not Cancer Driver No 1 hippie, biogrid 86 255 36 36 0
CLK1_ENST00000321356 CLK1 P49759 Dual specificity protein kinase CLK1 chr2 Not Cancer Driver No 1 hippie 64 131 21 21 0
CLK2 CLK2 P49760 Dual specificity protein kinase CLK2 chr1 Not Cancer Driver No 1 hippie 104 151 37 37 0
COMTD1 COMTD1 Q86VU5 Catechol O-methyltransferase domain-containing protein 1 chr10 Not Cancer Driver No 1 hippie, biogrid 11 23 0 0 0
CST11 CST11 Q9H112 Cystatin-11 chr20 Not Cancer Driver No 1 hippie, biogrid 38 6 0 0 0
CYSRT1 CYSRT1 B8A4K4 Cysteine-rich tail protein 1 chr9 Not Cancer Driver No 1 intact, hippie 9 142 5 5 0
DBN1_ENST00000309007 DBN1 Q16643 Drebrin chr5 Not Cancer Driver No 1 hippie, biogrid 84 510 73 73 0
DNAJC5 DNAJC5 Q9H3Z4 DnaJ homolog subfamily C member 5 chr20 Not Cancer Driver No 1 hippie, biogrid 23 46 6 6 1
DUOXA2 DUOXA2 Q1HG44 Dual oxidase maturation factor 2 chr15 Not Cancer Driver No 1 hippie, biogrid 40 0 0 0 0
ECEL1 ECEL1 O95672 Endothelin-converting enzyme-like 1 chr2 Not Cancer Driver No 1 hippie, biogrid 103 22 2 2 4
EDDM3A EDDM3A Q14507 Epididymal secretory protein E3-alpha chr14 Not Cancer Driver No 1 hippie, biogrid 27 0 0 0 0
EDN1 EDN1 P05305 Endothelin-1 chr6 Not Cancer Driver No 1 hippie 37 97 20 20 3
ENTPD2 ENTPD2 Q9Y5L3 Ectonucleoside triphosphate diphosphohydrolase 2 chr9 Not Cancer Driver No 1 hippie, biogrid 36 32 0 0 0
FAF2 FAF2 Q96CS3 FAS-associated factor 2 chr5 Not Cancer Driver No 1 hippie, biogrid 54 171 16 16 0
FAM160A1_ENST00000505231 FHIP1A Q05DH4 FHF complex subunit HOOK interacting protein 1A chr4 Not Cancer Driver No 1 intact 47 341 8 8 0
FAM160A2_ENST00000449352 FHIP1B Q8N612 FHF complex subunit HOOK interacting protein 1B chr11 Not Cancer Driver No 1 intact 129 415 54 54 0
FBXO2 FBXO2 Q9UK22 F-box only protein 2 chr1 Not Cancer Driver No 1 hippie, biogrid 21 75 1 1 0
FBXO6 FBXO6 Q9NRD1 F-box only protein 6 chr1 Not Cancer Driver No 1 hippie 31 27 3 3 0
FKBP10 FKBP10 Q96AY3 Peptidyl-prolyl cis-trans isomerase FKBP10 chr17 Not Cancer Driver No 1 hippie, biogrid 60 134 8 8 3
FUT3_ENST00000589620 FUT3 P21217 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3 chr19 Not Cancer Driver No 2 hippie, biogrid 77 33 9 9 0
FUT8_ENST00000394586 FUT8 Q9BYC5 Alpha-(1,6)-fucosyltransferase chr14 Not Cancer Driver No 1 hippie, biogrid 79 80 19 19 1
HLA-DPA1 HLA-DPA1 P20036 HLA class II histocompatibility antigen, DP alpha 1 chain chr6 Not Cancer Driver No 1 hippie, biogrid 37 30 4 4 0
HLA-DPB1 HLA-DPB1 P04440 HLA class II histocompatibility antigen, DP beta 1 chain chr6 Not Cancer Driver No 1 hippie, biogrid 38 39 4 4 0
HLA-G_ENST00000360323 HLA-G P17693 HLA class I histocompatibility antigen, alpha chain G chr6 Not Cancer Driver No 1 hippie, biogrid 94 85 22 22 0
KNG1 KNG1 P01042 Kininogen-1 chr3 Not Cancer Driver No 1 hippie 130 294 66 66 1
KRTAP1-3 KRTAP1-3 Q8IUG1 Keratin-associated protein 1-3 chr17 Not Cancer Driver No 1 intact, hippie 31 0 0 0 0
KRTAP10-1 KRTAP10-1 P60331 Keratin-associated protein 10-1 chr21 Not Cancer Driver No 1 hippie 51 0 0 0 0
KRTAP10-5 KRTAP10-5 P60370 Keratin-associated protein 10-5 chr21 Not Cancer Driver No 1 intact, hippie 76 0 0 0 0
KRTAP10-8 KRTAP10-8 P60410 Keratin-associated protein 10-8 chr21 Not Cancer Driver No 1 intact, hippie 51 0 0 0 0
LAMP1 LAMP1 P11279 Lysosome-associated membrane glycoprotein 1 chr13 Not Cancer Driver No 1 hippie 47 93 10 10 0
LAMP3 LAMP3 Q9UQV4 Lysosome-associated membrane glycoprotein 3 chr3 Not Cancer Driver No 1 hippie, biogrid 67 222 38 38 0
LAMTOR1 LAMTOR1 Q6IAA8 Ragulator complex protein LAMTOR1 chr11 Not Cancer Driver No 1 hippie, biogrid 13 96 7 7 0
LAMTOR2 LAMTOR2 Q9Y2Q5 Ragulator complex protein LAMTOR2 chr1 Not Cancer Driver No 1 hippie, biogrid 12 0 0 0 0
LGALS1 LGALS1 P09382 Galectin-1 chr22 Not Cancer Driver No 1 hippie, biogrid 16 0 0 0 0
LGALS3 LGALS3 P17931 Galectin-3 chr14 Not Cancer Driver No 3 intact, hippie, biogrid 15 133 6 6 0
LGALS8_ENST00000366584 LGALS8 O00214 Galectin-8 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 43 31 6 6 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 Not Cancer Driver No 2 hippie, biogrid 54 65 16 16 0
LLCFC1 LLCFC1 Q96L11-3 Isoform 3 of Sperm-egg fusion protein LLCFC1 chr7 Not Cancer Driver No 1 hippie 42 62 17 17 0
LRRC32_ENST00000404995 LRRC32 Q14392 Transforming growth factor beta activator LRRC32 chr11 Not Cancer Driver No 1 hippie, biogrid 130 28 4 4 0
LYPD1 LYPD1 Q8N2G4 Ly6/PLAUR domain-containing protein 1 chr2 Not Cancer Driver No 1 hippie, biogrid 20 5 0 0 0
LYZL1 LYZL1 Q6UWQ5-2 Isoform 2 of Lysozyme-like protein 1 chr10 Not Cancer Driver No 1 hippie, biogrid 32 6 4 4 0
MTDH MTDH Q86UE4 Protein LYRIC chr8 Not Cancer Driver No 1 hippie 83 516 81 81 0
MTNR1A MTNR1A P48039 Melatonin receptor type 1A chr4 Not Cancer Driver No 1 intact, hippie 72 0 0 0 0
MYOC MYOC Q99972 Myocilin chr1 Not Cancer Driver No 1 hippie 92 196 43 43 58
NCR3 NCR3 O14931 Natural cytotoxicity triggering receptor 3 chr6 Not Cancer Driver No 1 hippie, biogrid 26 31 2 2 0
NPB NPB Q8NG41 Neuropeptide B chr17 Not Cancer Driver No 2 hippie, biogrid 6 22 1 1 0
NRAS NRAS P01111 GTPase NRas chr1 Census, Compendium Yes 1 hippie, biogrid 284 10 0 0 14
PATE1 PATE1 Q8WXA2 Prostate and testis expressed protein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 36 0 0 0 0
PCDHA9 PCDHA9 Q9Y5H5 Protocadherin alpha-9 chr5 Not Cancer Driver No 1 hippie, biogrid 319 260 81 81 0
PDGFRA PDGFRA P16234 Platelet-derived growth factor receptor alpha chr4 Census, Compendium Yes 1 hippie, biogrid 290 173 45 45 2
PRG2 PRG2 P13727 Bone marrow proteoglycan chr11 Not Cancer Driver No 1 hippie, biogrid 45 65 15 15 0
PTCH1 PTCH1 Q13635 Protein patched homolog 1 chr9 Census, Compendium Yes 1 hippie, biogrid 243 382 67 67 18
PTPRK_ENST00000368215 PTPRK Q15262 Receptor-type tyrosine-protein phosphatase kappa chr6 Census, Compendium Yes 3 intact, hippie, biogrid 292 302 57 57 0
RAB11A RAB11A P62491 Ras-related protein Rab-11A chr15 Not Cancer Driver No 1 hippie, biogrid 31 43 4 4 0
RAB2A RAB2A P61019 Ras-related protein Rab-2A chr8 Not Cancer Driver No 1 hippie, biogrid 22 58 4 4 0
RAB35 RAB35 Q15286 Ras-related protein Rab-35 chr12 Not Cancer Driver No 1 hippie, biogrid 25 25 2 2 0
RAB4A RAB4A P20338 Ras-related protein Rab-4A chr1 Not Cancer Driver No 1 hippie, biogrid 26 32 11 11 0
RAB5A RAB5A P20339 Ras-related protein Rab-5A chr3 Not Cancer Driver No 1 hippie, biogrid 32 65 15 15 0
RAB5C_ENST00000393860 RAB5C P51148 Ras-related protein Rab-5C chr17 Not Cancer Driver No 1 hippie, biogrid 24 50 4 4 0
RAB7A RAB7A P51149 Ras-related protein Rab-7a chr3 Not Cancer Driver No 1 biogrid 27 11 0 0 4
RAB9A RAB9A P51151 Ras-related protein Rab-9A chrX Not Cancer Driver No 1 hippie, biogrid 18 21 1 1 0
RAC3 RAC3 P60763 Ras-related C3 botulinum toxin substrate 3 chr17 Not Cancer Driver No 1 hippie 24 0 0 0 4
RLN1 RLN1 P04808 Prorelaxin H1 chr9 Not Cancer Driver No 1 hippie, biogrid 24 38 3 3 0
RPL19 RPL19 P84098 60S ribosomal protein L19 chr17 Not Cancer Driver No 1 hippie, biogrid 30 121 21 21 0
RPS26_ENST00000646449 RPS26 P62854 40S ribosomal protein S26 chr12 Not Cancer Driver No 1 hippie, biogrid 9 52 5 5 2
RPSA_ENST00000301821 RPSA P08865 40S ribosomal protein SA chr3 Not Cancer Driver No 1 hippie, biogrid 22 95 6 6 5
SDF2L1 SDF2L1 Q9HCN8 Stromal cell-derived factor 2-like protein 1 chr22 Not Cancer Driver No 1 hippie, biogrid 16 130 9 9 0
SFTPC SFTPC P11686 Pulmonary surfactant-associated protein C chr8 Not Cancer Driver No 1 hippie, biogrid 21 19 2 2 5
SSR4_ENST00000370086 SSR4 P51571 Translocon-associated protein subunit delta chrX Not Cancer Driver No 1 hippie, biogrid 21 0 0 0 0
ST8SIA5_ENST00000315087 ST8SIA5 O15466 Alpha-2,8-sialyltransferase 8E chr18 Not Cancer Driver No 1 hippie, biogrid 98 0 0 0 0
STX7 STX7 O15400 Syntaxin-7 chr6 Not Cancer Driver No 1 hippie, biogrid 29 164 14 14 0
SUSD4 SUSD4 Q5VX71 Sushi domain-containing protein 4 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 85 134 27 27 0
TDGF1 TDGF1 P13385 Teratocarcinoma-derived growth factor 1 chr3 Not Cancer Driver No 1 hippie, biogrid 39 25 2 2 0
TMEM106A TMEM106A Q96A25 Transmembrane protein 106A chr17 Not Cancer Driver No 1 hippie, biogrid 26 9 1 1 0
TMEM106B TMEM106B Q9NUM4 Transmembrane protein 106B chr7 Not Cancer Driver No 1 hippie 31 56 4 4 1
TMPRSS11B TMPRSS11B Q86T26 Transmembrane protease serine 11B chr4 Not Cancer Driver No 1 hippie, biogrid 95 5 0 0 0
TMPRSS2_ENST00000458356 TMPRSS2 O15393 Transmembrane protease serine 2 chr21 Census Yes 1 hippie, biogrid 66 25 5 5 0
TMPRSS4_ENST00000437212 TMPRSS4 Q9NRS4 Transmembrane protease serine 4 chr11 Not Cancer Driver No 1 hippie, biogrid 47 35 4 4 0
UGT1A7 UGT1A7 Q9HAW7 UDP-glucuronosyltransferase 1A7 chr2 Not Cancer Driver No 1 hippie, biogrid 110 11 2 2 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
VMA21 VMA21 Q3ZAQ7 Vacuolar ATPase assembly integral membrane protein VMA21 chrX Not Cancer Driver No 1 hippie, biogrid 18 7 1 1 0