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E2F2 ,E2F2 ,Q14209
  • Number of Interaction partner in intact: 1
  • Number of Interaction partner in biogrid: 10
  • Number of Interaction partner in hippie: 37
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ARID3A ARID3A Q99856 AT-rich interactive domain-containing protein 3A chr19 Not Cancer Driver No 1 hippie 55 432 37 37 0
ATAD2 ATAD2 Q6PL18 ATPase family AAA domain-containing protein 2 chr8 Not Cancer Driver No 1 hippie 227 647 113 113 0
BCAR1_ENST00000162330 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 Not Cancer Driver No 1 hippie, biogrid 108 677 75 75 0
BRD2_ENST00000374831 BRD2 P25440 Bromodomain-containing protein 2 chr6 Not Cancer Driver No 1 hippie 108 632 85 85 0
CCNF CCNF P41002 Cyclin-F chr16 Not Cancer Driver No 1 hippie 106 221 23 23 3
CDK3_ENST00000448471 CDK3 Q00526 Cyclin-dependent kinase 3 chr17 Not Cancer Driver No 1 hippie 40 17 2 2 0
DCAF13_ENST00000612750 DCAF13 Q9NV06 DDB1- and CUL4-associated factor 13 chr8 Not Cancer Driver No 1 hippie 85 101 18 18 0
E2F1 E2F1 Q01094 Transcription factor E2F1 chr20 Not Cancer Driver No 2 hippie, biogrid 49 272 23 23 0
E2F3 E2F3 O00716 Transcription factor E2F3 chr6 Not Cancer Driver No 1 hippie, biogrid 46 253 20 20 0
E2F4 E2F4 Q16254 Transcription factor E2F4 chr16 Not Cancer Driver No 1 hippie, biogrid 44 242 32 32 0
E2F5 E2F5 Q15329 Transcription factor E2F5 chr8 Not Cancer Driver No 1 hippie, biogrid 37 176 15 15 0
E2F6 E2F6 O75461 Transcription factor E2F6 chr2 Not Cancer Driver No 1 hippie, biogrid 20 105 10 10 0
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
FHL2_ENST00000408995 FHL2 Q14192 Four and a half LIM domains protein 2 chr2 Not Cancer Driver No 1 hippie 30 0 0 0 0
GIT2 GIT2 Q14161 ARF GTPase-activating protein GIT2 chr12 Not Cancer Driver No 1 hippie 83 492 47 47 0
GNB5 GNB5 O14775 Guanine nucleotide-binding protein subunit beta-5 chr15 Not Cancer Driver No 1 hippie 60 16 1 1 1
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 hippie 28 10 1 1 0
KMT2A_ENST00000389506 KMT2A Q03164 Histone-lysine N-methyltransferase 2A chr11 Census, Compendium Yes 1 hippie 446 3145 338 338 0
KMT2D KMT2D O14686 Histone-lysine N-methyltransferase 2D chr12 Census, Compendium Yes 1 hippie 773 4386 552 552 13
KMT5A KMT5A Q9NQR1-2 Isoform 2 of N-lysine methyltransferase KMT5A chr12 Not Cancer Driver No 1 hippie 41 225 22 22 0
L3MBTL3_ENST00000368136 L3MBTL3 Q96JM7 Lethal(3)malignant brain tumor-like protein 3 chr6 Not Cancer Driver No 1 hippie 117 351 59 59 0
MCPH1 MCPH1 Q8NEM0 Microcephalin chr8 Not Cancer Driver No 1 intact, hippie 110 446 62 62 1
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 110 101 8 8 0
MYCN MYCN P04198 N-myc proto-oncogene protein chr2 Census, Compendium Yes 1 hippie 71 415 64 64 3
PCGF6 PCGF6 Q9BYE7 Polycomb group RING finger protein 6 chr10 Not Cancer Driver No 1 hippie, biogrid 29 142 11 11 0
RB1 RB1 P06400 Retinoblastoma-associated protein chr13 Census, Compendium Yes 2 hippie, biogrid 140 282 32 32 22
RBL1 RBL1 P28749 Retinoblastoma-like protein 1 chr20 Not Cancer Driver No 1 hippie 140 335 41 41 0
RNF144A RNF144A P50876 E3 ubiquitin-protein ligase RNF144A chr2 Not Cancer Driver No 1 hippie 63 0 0 0 0
RYBP RYBP Q8N488 RING1 and YY1-binding protein chr3 Not Cancer Driver No 1 hippie 37 214 37 37 0
SHMT2 SHMT2 P34897 Serine hydroxymethyltransferase, mitochondrial chr12 Not Cancer Driver No 1 hippie 57 58 5 5 1
SP1 SP1 P08047 Transcription factor Sp1 chr12 Not Cancer Driver No 1 hippie 96 599 71 71 0
SPIB SPIB Q01892 Transcription factor Spi-B chr19 Not Cancer Driver No 1 hippie 40 136 24 24 0
TFDP1 TFDP1 Q14186 Transcription factor Dp-1 chr13 Not Cancer Driver No 2 hippie, biogrid 82 245 47 47 0
TFDP2 TFDP2 Q14188 Transcription factor Dp-2 chr3 Not Cancer Driver No 4 hippie, biogrid 62 248 33 33 0
TRIM24 TRIM24 O15164 Transcription intermediary factor 1-alpha chr7 Census, Compendium Yes 1 hippie 120 537 61 61 0
UCHL5 UCHL5 Q9Y5K5 Ubiquitin carboxyl-terminal hydrolase isozyme L5 chr1 Not Cancer Driver No 1 hippie 33 41 7 7 0
YY1 YY1 P25490 Transcriptional repressor protein YY1 chr14 Not Cancer Driver No 1 hippie 37 336 26 26 2