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DUSP10 ,DUSP10 ,Q9Y6W6
  • Uniprot Accession= Q9Y6W6
  • Ensembl Transcript= ENST00000366899.3
  • Uniprot Name= DUSP10
  • Name= Dual specificity protein phosphatase 10
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 16
  • Number of Interaction partner in biogrid: 5
  • Number of Interaction partner in hippie: 78
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTA2 ACTA2 P62736 Actin, aortic smooth muscle chr10 Not Cancer Driver No 2 hippie, biogrid 50 39 4 4 17
ACTBL2 ACTBL2 Q562R1 Beta-actin-like protein 2 chr5 Not Cancer Driver No 1 intact, hippie, biogrid 73 29 5 5 0
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 2 intact, hippie, biogrid 112 43 5 5 5
ACTC1 ACTC1 P68032 Actin, alpha cardiac muscle 1 chr15 Not Cancer Driver No 1 hippie, biogrid 114 48 19 19 11
ATN1_ENST00000396684 ATN1 P54259 Atrophin-1 chr12 Not Cancer Driver No 1 intact 141 1176 139 139 6
BACE2 BACE2 Q9Y5Z0 Beta-secretase 2 chr21 Not Cancer Driver No 1 intact, hippie 61 23 2 2 0
C5orf22 C5orf22 Q49AR2 UPF0489 protein C5orf22 chr5 Not Cancer Driver No 1 hippie 56 89 10 10 0
CASK_ENST00000378163 CASK O14936 Peripheral plasma membrane protein CASK chrX Not Cancer Driver No 1 intact, hippie 118 285 45 45 4
CDC45_ENST00000407835 CDC45 O75419 Cell division control protein 45 homolog chr22 Not Cancer Driver No 1 hippie 73 66 16 16 5
CIAO1 CIAO1 O76071 Probable cytosolic iron-sulfur protein assembly protein CIAO1 chr2 Not Cancer Driver No 1 hippie 30 20 2 2 0
CMTM6 CMTM6 Q9NX76 CKLF-like MARVEL transmembrane domain-containing protein 6 chr3 Not Cancer Driver No 1 hippie 10 30 0 0 0
CNKSR1 CNKSR1 Q969H4 Connector enhancer of kinase suppressor of ras 1 chr1 Not Cancer Driver No 1 hippie 118 405 68 68 0
CRYAA CRYAA P02489 Alpha-crystallin A chain chr21 Not Cancer Driver No 1 intact, hippie 34 42 11 11 10
CTNNA1 CTNNA1 P35221 Catenin alpha-1 chr5 Census Yes 1 hippie 126 268 35 35 4
DCAF7 DCAF7 P61962 DDB1- and CUL4-associated factor 7 chr17 Not Cancer Driver No 1 hippie 48 0 0 0 0
DICER1 DICER1 Q9UPY3 Endoribonuclease Dicer chr14 Census, Compendium Yes 1 hippie 264 362 45 45 4
DLG1_ENST00000419354 DLG1 Q12959 Disks large homolog 1 chr3 Not Cancer Driver No 1 hippie 120 460 67 67 0
DLG4_ENST00000399506 DLG4 P78352 Disks large homolog 4 chr17 Not Cancer Driver No 1 hippie 116 232 55 55 0
DNAJC10 DNAJC10 Q8IXB1 DnaJ homolog subfamily C member 10 chr2 Not Cancer Driver No 1 hippie 110 36 3 3 0
DYNC1H1 DYNC1H1 Q14204 Cytoplasmic dynein 1 heavy chain 1 chr14 Not Cancer Driver No 1 intact, hippie 505 495 62 62 21
ECI1 ECI1 P42126 Enoyl-CoA delta isomerase 1, mitochondrial chr16 Not Cancer Driver No 1 hippie 27 14 0 0 0
EFHD1 EFHD1 Q9BUP0 EF-hand domain-containing protein D1 chr2 Not Cancer Driver No 2 hippie, biogrid 30 94 7 7 0
ERBB4 ERBB4 Q15303 Receptor tyrosine-protein kinase erbB-4 chr2 Census, Compendium Yes 1 intact, hippie 428 323 116 116 2
FAAP100 FAAP100 Q0VG06 Fanconi anemia core complex-associated protein 100 chr17 Not Cancer Driver No 1 hippie 93 207 31 31 0
FBN2_ENST00000262464 FBN2 P35556 Fibrillin-2 chr5 Compendium Yes 1 hippie 607 135 24 24 30
FBXO3 FBXO3 Q9UK99 F-box only protein 3 chr11 Not Cancer Driver No 1 hippie 56 51 7 7 0
FGFR3_ENST00000440486 FGFR3 P22607 Fibroblast growth factor receptor 3 chr4 Census, Compendium Yes 1 intact, hippie 173 241 26 26 37
FHL2_ENST00000408995 FHL2 Q14192 Four and a half LIM domains protein 2 chr2 Not Cancer Driver No 1 hippie 30 0 0 0 0
FHL3 FHL3 Q13643 Four and a half LIM domains protein 3 chr1 Not Cancer Driver No 1 hippie 33 0 0 0 0
FN1 FN1 P02751 Fibronectin chr2 Compendium Yes 1 intact, hippie 394 1243 185 185 8
FNDC3B_ENST00000416957 FNDC3B Q53EP0 Fibronectin type III domain-containing protein 3B chr3 Not Cancer Driver No 1 intact, hippie 164 433 53 53 0
GOPC GOPC Q9HD26 Golgi-associated PDZ and coiled-coil motif-containing protein chr6 Census Yes 1 hippie 56 263 34 34 0
GRIN2C GRIN2C Q14957 Glutamate receptor ionotropic, NMDA 2C chr17 Not Cancer Driver No 1 intact, hippie 111 276 6 6 0
GSN GSN P06396 Gelsolin chr9 Not Cancer Driver No 1 intact, hippie 76 316 28 28 2
HOXA1_ENST00000643460 HOXA1 P49639 Homeobox protein Hox-A1 chr7 Not Cancer Driver No 1 hippie 90 262 68 68 0
HRAS HRAS P01112 GTPase HRas chr11 Census, Compendium Yes 1 intact, hippie 107 16 4 4 18
HSPA4L_ENST00000508776 HSPA4L O95757 Heat shock 70 kDa protein 4L chr4 Not Cancer Driver No 1 hippie 105 266 28 28 0
HSPBP1 HSPBP1 Q9NZL4 Hsp70-binding protein 1 chr19 Not Cancer Driver No 1 hippie 29 130 7 7 0
HTT HTT P42858 Huntingtin chr4 Not Cancer Driver No 1 intact, hippie 336 666 69 69 2
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 Not Cancer Driver No 1 hippie 183 265 37 37 6
KRTAP3-2 KRTAP3-2 Q9BYR7 Keratin-associated protein 3-2 chr17 Not Cancer Driver No 1 hippie 18 0 0 0 0
LIN7C LIN7C Q9NUP9 Protein lin-7 homolog C chr11 Not Cancer Driver No 1 hippie 22 102 11 11 0
LRP1 LRP1 Q07954 Prolow-density lipoprotein receptor-related protein 1 chr12 Not Cancer Driver No 1 hippie 664 317 52 52 1
MAPK10_ENST00000515650 MAPK10 P53779 Mitogen-activated protein kinase 10 chr4 Not Cancer Driver No 1 hippie 88 107 16 16 0
MAPK11 MAPK11 Q15759 Mitogen-activated protein kinase 11 chr22 Not Cancer Driver No 1 hippie 23 64 2 2 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 Not Cancer Driver No 1 hippie 39 25 1 1 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 Census, Compendium Yes 1 hippie 62 2 0 0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 Not Cancer Driver No 1 hippie 38 49 5 5 0
MAPK8_ENST00000374189 MAPK8 P45983 Mitogen-activated protein kinase 8 chr10 Not Cancer Driver No 1 hippie 64 94 9 9 0
MAPK9 MAPK9 P45984 Mitogen-activated protein kinase 9 chr5 Not Cancer Driver No 1 hippie 59 90 8 8 0
MPDZ MPDZ O75970 Multiple PDZ domain protein chr9 Not Cancer Driver No 1 hippie 287 858 122 122 0
MPP7 MPP7 Q5T2T1 MAGUK p55 subfamily member 7 chr10 Not Cancer Driver No 1 hippie 132 199 72 72 0
MRE11 MRE11 P49959 Double-strand break repair protein MRE11 chr11 Not Cancer Driver No 1 hippie 84 292 35 35 1
NUP205 NUP205 Q92621 Nuclear pore complex protein Nup205 chr7 Not Cancer Driver No 1 hippie 251 101 16 16 1
OTUD4_ENST00000447906 OTUD4 Q01804 OTU domain-containing protein 4 chr4 Not Cancer Driver No 1 hippie 148 788 120 120 0
PNMA2 PNMA2 Q9UL42 Paraneoplastic antigen Ma2 chr8 Not Cancer Driver No 1 hippie 52 45 5 5 0
PPP2CA PPP2CA P67775 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform chr5 Not Cancer Driver No 1 hippie 41 12 1 1 8
PPP2R1A PPP2R1A P30153 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 Census, Compendium Yes 1 hippie 179 0 0 0 4
PPP2R2A_ENST00000380737 PPP2R2A P63151 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform chr8 Not Cancer Driver No 1 hippie 60 68 10 10 0
PPP2R2D PPP2R2D Q66LE6 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform chr10 Not Cancer Driver No 1 hippie 50 65 9 9 0
PPP6R3_ENST00000393800 PPP6R3 Q5H9R7 Serine/threonine-protein phosphatase 6 regulatory subunit 3 chr11 Not Cancer Driver No 1 hippie 108 389 52 52 0
PRUNE1 PRUNE1 Q86TP1 Exopolyphosphatase PRUNE1 chr1 Not Cancer Driver No 1 hippie 43 93 14 14 4
PTK7_ENST00000230419 PTK7 Q13308 Inactive tyrosine-protein kinase 7 chr6 Not Cancer Driver No 1 hippie 153 359 58 58 0
PTPN2 PTPN2 P17706 Tyrosine-protein phosphatase non-receptor type 2 chr18 Not Cancer Driver No 1 hippie 57 120 14 14 0
RAD50 RAD50 Q92878 DNA repair protein RAD50 chr5 Not Cancer Driver No 1 hippie 157 730 84 84 0
ROR2 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 Not Cancer Driver No 1 hippie 203 299 71 71 5
RPS11 RPS11 P62280 40S ribosomal protein S11 chr19 Not Cancer Driver No 1 intact, hippie 18 6 0 0 0
SAMHD1 SAMHD1 Q9Y3Z3 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 chr20 Not Cancer Driver No 1 hippie 104 91 14 14 13
SKIV2L SKIV2L Q15477 Helicase SKI2W chr6 Not Cancer Driver No 1 hippie 140 390 54 54 1
SLX1A_ENST00000345535 SLX1A Q9BQ83-2 Isoform 2 of Structure-specific endonuclease subunit SLX1 chr16 Not Cancer Driver No 1 hippie 5 27 0 0 0
SNX2 SNX2 O60749 Sorting nexin-2 chr5 Not Cancer Driver No 1 hippie 45 218 18 18 0
SORL1 SORL1 Q92673 Sortilin-related receptor chr11 Not Cancer Driver No 1 hippie 374 87 10 10 0
SPRR3 SPRR3 Q9UBC9 Small proline-rich protein 3 chr1 Not Cancer Driver No 1 hippie 57 169 57 57 0
TCOF1 TCOF1 Q13428 Treacle protein chr5 Not Cancer Driver No 1 hippie 142 1454 141 141 1
TTC37 TTC37 Q6PGP7 Tetratricopeptide repeat protein 37 chr5 Not Cancer Driver No 1 hippie 164 59 3 3 3
TXNDC9 TXNDC9 O14530 Thioredoxin domain-containing protein 9 chr2 Not Cancer Driver No 1 hippie 20 40 5 5 0
UBQLN1 UBQLN1 Q9UMX0 Ubiquilin-1 chr9 Not Cancer Driver No 1 hippie 64 543 58 58 0
UTRN UTRN P46939 Utrophin chr6 Not Cancer Driver No 1 hippie 476 1283 183 183 0
WDR61 WDR61 Q9GZS3 WD repeat-containing protein 61 chr15 Not Cancer Driver No 1 hippie 25 7 1 1 0