Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ATR | ATR | Q13535 | Serine/threonine-protein kinase ATR | chr3 | Census, Compendium | Yes | 1 | hippie | 338 | 106 | 14 | 14 | 1 |
| AURKB_ENST00000585124 | AURKB | Q96GD4 | Aurora kinase B | chr17 | Not Cancer Driver | No | 1 | hippie | 51 | 63 | 8 | 8 | 0 |
| BUB3 | BUB3 | O43684 | Mitotic checkpoint protein BUB3 | chr10 | Not Cancer Driver | No | 1 | hippie | 46 | 60 | 6 | 6 | 0 |
| CAMK2A_ENST00000348628 | CAMK2A | Q9UQM7 | Calcium/calmodulin-dependent protein kinase type II subunit alpha | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 83 | 62 | 10 | 10 | 7 |
| CAMK2D_ENST00000342666 | CAMK2D | Q13557 | Calcium/calmodulin-dependent protein kinase type II subunit delta | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 57 | 84 | 10 | 10 | 0 |
| CARNMT1 | CARNMT1 | Q8N4J0 | Carnosine N-methyltransferase | chr9 | Not Cancer Driver | No | 1 | hippie | 42 | 75 | 1 | 1 | 0 |
| CCNA2_ENST00000618014 | CCNA2 | P20248 | Cyclin-A2 | chr4 | Not Cancer Driver | No | 1 | hippie | 45 | 186 | 19 | 19 | 0 |
| CCNF | CCNF | P41002 | Cyclin-F | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 106 | 221 | 23 | 23 | 3 |
| CCT2 | CCT2 | P78371 | T-complex protein 1 subunit beta | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 63 | 46 | 3 | 3 | 0 |
| CCT3 | CCT3 | P49368 | T-complex protein 1 subunit gamma | chr1 | Not Cancer Driver | No | 2 | hippie, biogrid | 71 | 95 | 12 | 12 | 0 |
| CCT5 | CCT5 | P48643 | T-complex protein 1 subunit epsilon | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 83 | 72 | 10 | 10 | 1 |
| CCT6B | CCT6B | Q92526 | T-complex protein 1 subunit zeta-2 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 90 | 1 | 0 | 0 | 0 |
| CCT7 | CCT7 | Q99832 | T-complex protein 1 subunit eta | chr2 | Not Cancer Driver | No | 2 | hippie, biogrid | 59 | 36 | 6 | 6 | 0 |
| CDK1 | CDK1 | P06493 | Cyclin-dependent kinase 1 | chr10 | Not Cancer Driver | No | 1 | hippie | 40 | 1 | 0 | 0 | 0 |
| CDK2 | CDK2 | P24941 | Cyclin-dependent kinase 2 | chr12 | Not Cancer Driver | No | 1 | hippie | 24 | 0 | 0 | 0 | 0 |
| CDKN1A_ENST00000373711 | CDKN1A | P38936 | Cyclin-dependent kinase inhibitor 1 | chr6 | Census, Compendium | Yes | 1 | hippie | 48 | 121 | 30 | 30 | 0 |
| CDT1 | CDT1 | Q9H211 | DNA replication factor Cdt1 | chr16 | Not Cancer Driver | No | 1 | hippie | 60 | 377 | 35 | 35 | 5 |
| CFTR | CFTR | P13569 | Cystic fibrosis transmembrane conductance regulator | chr7 | Not Cancer Driver | No | 1 | hippie | 287 | 145 | 18 | 18 | 151 |
| CHEK1_ENST00000428830 | CHEK1 | O14757 | Serine/threonine-protein kinase Chk1 | chr11 | Not Cancer Driver | No | 1 | hippie | 58 | 86 | 16 | 16 | 0 |
| COPS2_ENST00000388901 | COPS2 | P61201 | COP9 signalosome complex subunit 2 | chr15 | Not Cancer Driver | No | 1 | hippie | 59 | 59 | 9 | 9 | 0 |
| COPS3 | COPS3 | Q9UNS2 | COP9 signalosome complex subunit 3 | chr17 | Not Cancer Driver | No | 1 | hippie | 55 | 67 | 10 | 10 | 0 |
| COPS4_ENST00000264389 | COPS4 | Q9BT78 | COP9 signalosome complex subunit 4 | chr4 | Not Cancer Driver | No | 1 | hippie | 50 | 13 | 0 | 0 | 0 |
| COPS5 | COPS5 | Q92905 | COP9 signalosome complex subunit 5 | chr8 | Not Cancer Driver | No | 1 | hippie | 36 | 32 | 7 | 7 | 0 |
| COPS6 | COPS6 | Q7L5N1 | COP9 signalosome complex subunit 6 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 38 | 30 | 6 | 6 | 0 |
| COPS7A_ENST00000534947 | COPS7A | Q9UBW8 | COP9 signalosome complex subunit 7a | chr12 | Not Cancer Driver | No | 1 | hippie | 32 | 74 | 10 | 10 | 0 |
| COPS8 | COPS8 | Q99627 | COP9 signalosome complex subunit 8 | chr2 | Not Cancer Driver | No | 2 | hippie, biogrid | 25 | 14 | 2 | 2 | 0 |
| CTSV | CTSV | O60911 | Cathepsin L2 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 55 | 7 | 1 | 1 | 0 |
| CUL4A | CUL4A | Q13619 | Cullin-4A | chr13 | Not Cancer Driver | No | 2 | hippie, biogrid | 64 | 102 | 2 | 2 | 0 |
| CUL4B | CUL4B | Q13620 | Cullin-4B | chrX | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 138 | 207 | 38 | 38 | 2 |
| DCAF15 | DCAF15 | Q66K64 | DDB1- and CUL4-associated factor 15 | chr19 | Not Cancer Driver | No | 1 | hippie | 50 | 173 | 18 | 18 | 0 |
| DDA1 | DDA1 | Q9BW61 | DET1- and DDB1-associated protein 1 | chr19 | Not Cancer Driver | No | 2 | hippie, biogrid | 10 | 70 | 9 | 9 | 0 |
| DDB1 | DDB1 | Q16531 | DNA damage-binding protein 1 | chr11 | Not Cancer Driver | No | 1 | biogrid | 126 | 50 | 8 | 8 | 4 |
| DDB2 | DDB2 | Q92466 | DNA damage-binding protein 2 | chr11 | Census, Compendium | Yes | 1 | hippie | 45 | 70 | 5 | 5 | 2 |
| DEF8 | DEF8 | Q6ZN54 | Differentially expressed in FDCP 8 homolog | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 123 | 23 | 23 | 0 |
| DNAJA2 | DNAJA2 | O60884 | DnaJ homolog subfamily A member 2 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 174 | 27 | 27 | 0 |
| ERCC5 | ERCC5 | P28715 | DNA excision repair protein ERCC-5 | chr13 | Census | Yes | 1 | hippie | 175 | 816 | 121 | 121 | 6 |
| FBH1_ENST00000362091 | FBH1 | Q8NFZ0 | F-box DNA helicase 1 | chr10 | Not Cancer Driver | No | 1 | hippie | 139 | 192 | 32 | 32 | 0 |
| FBXO11 | FBXO11 | Q86XK2 | F-box only protein 11 | chr2 | Census, Compendium | Yes | 1 | hippie | 113 | 242 | 22 | 22 | 8 |
| FBXO38_ENST00000340253 | FBXO38 | Q6PIJ6 | F-box only protein 38 | chr5 | Not Cancer Driver | No | 1 | hippie | 133 | 440 | 48 | 48 | 1 |
| FLG | FLG | P20930 | Filaggrin | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 1612 | 3956 | 1593 | 1593 | 0 |
| GATD1 | GATD1 | Q8NB37 | Glutamine amidotransferase-like class 1 domain-containing protein 1 | chr11 | Not Cancer Driver | No | 1 | hippie | 24 | 2 | 0 | 0 | 0 |
| GLMN | GLMN | Q92990 | Glomulin | chr1 | Not Cancer Driver | No | 2 | hippie, biogrid | 49 | 37 | 6 | 6 | 0 |
| GPS1_ENST00000306823 | GPS1 | Q13098 | COP9 signalosome complex subunit 1 | chr17 | Not Cancer Driver | No | 2 | hippie, biogrid | 62 | 106 | 14 | 14 | 0 |
| GRWD1 | GRWD1 | Q9BQ67 | Glutamate-rich WD repeat-containing protein 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 44 | 187 | 14 | 14 | 0 |
| HAL | HAL | P42357 | Histidine ammonia-lyase | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 98 | 34 | 6 | 6 | 4 |
| HLTF_ENST00000494055 | HLTF | Q14527 | Helicase-like transcription factor | chr3 | Not Cancer Driver | No | 1 | hippie | 121 | 353 | 40 | 40 | 0 |
| HSPA4 | HSPA4 | P34932 | Heat shock 70 kDa protein 4 | chr5 | Not Cancer Driver | No | 1 | hippie | 80 | 351 | 24 | 24 | 0 |
| KAT2A | KAT2A | Q92830 | Histone acetyltransferase KAT2A | chr17 | Not Cancer Driver | No | 1 | hippie | 88 | 251 | 17 | 17 | 0 |
| KLK7 | KLK7 | P49862 | Kallikrein-7 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 38 | 8 | 8 | 0 |
| KMT5A | KMT5A | Q9NQR1-2 | Isoform 2 of N-lysine methyltransferase KMT5A | chr12 | Not Cancer Driver | No | 1 | hippie | 41 | 225 | 22 | 22 | 0 |
| KPRP | KPRP | Q5T749 | Keratinocyte proline-rich protein | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 198 | 193 | 68 | 68 | 0 |
| LMBR1L | LMBR1L | Q6UX01 | Protein LMBR1L | chr12 | Not Cancer Driver | No | 1 | hippie | 57 | 4 | 0 | 0 | 0 |
| LYN | LYN | P07948 | Tyrosine-protein kinase Lyn | chr8 | Census | Yes | 1 | hippie | 95 | 84 | 12 | 12 | 0 |
| MDM2_ENST00000539479 | MDM2 | Q00987 | E3 ubiquitin-protein ligase Mdm2 | chr12 | Census, Compendium | Yes | 1 | hippie | 56 | 297 | 37 | 37 | 0 |
| MGMT | MGMT | B4DEE8 | Methylated-DNA--protein-cysteine methyltransferase | chr10 | Census | Yes | 1 | hippie | 43 | 40 | 15 | 15 | 0 |
| MSH2 | MSH2 | P43246 | DNA mismatch repair protein Msh2 | chr2 | Census | Yes | 1 | hippie | 92 | 37 | 4 | 4 | 70 |
| MSH6 | MSH6 | P52701 | DNA mismatch repair protein Msh6 | chr2 | Census | Yes | 1 | hippie | 154 | 386 | 41 | 41 | 6 |
| NSD2_ENST00000382892 | NSD2 | O96028 | Histone-lysine N-methyltransferase NSD2 | chr4 | Census, Compendium | Yes | 1 | hippie | 191 | 552 | 76 | 76 | 0 |
| PCNA | PCNA | P12004 | Proliferating cell nuclear antigen | chr20 | Not Cancer Driver | No | 1 | hippie | 30 | 22 | 3 | 3 | 1 |
| PDCD4 | PDCD4 | Q53EL6 | Programmed cell death protein 4 | chr10 | Not Cancer Driver | No | 1 | hippie | 57 | 187 | 32 | 32 | 0 |
| PDCL3 | PDCL3 | Q9H2J4 | Phosducin-like protein 3 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 48 | 73 | 13 | 13 | 0 |
| PFDN1 | PFDN1 | O60925 | Prefoldin subunit 1 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 8 | 42 | 4 | 4 | 0 |
| PFDN2 | PFDN2 | Q9UHV9 | Prefoldin subunit 2 | chr1 | Not Cancer Driver | No | 2 | hippie, biogrid | 18 | 111 | 11 | 11 | 0 |
| PLEKHA4 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 136 | 687 | 128 | 128 | 0 |
| POF1B_ENST00000262753 | POF1B | Q8WVV4 | Protein POF1B | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 154 | 391 | 104 | 104 | 1 |
| POLD4 | POLD4 | Q9HCU8 | DNA polymerase delta subunit 4 | chr11 | Not Cancer Driver | No | 1 | hippie | 8 | 50 | 3 | 3 | 0 |
| PTPN3 | PTPN3 | P26045 | Tyrosine-protein phosphatase non-receptor type 3 | chr9 | Not Cancer Driver | No | 1 | hippie | 139 | 214 | 28 | 28 | 0 |
| RAD18 | RAD18 | Q9NS91 | E3 ubiquitin-protein ligase RAD18 | chr3 | Not Cancer Driver | No | 1 | hippie | 59 | 328 | 43 | 43 | 0 |
| RBX1 | RBX1 | P62877 | E3 ubiquitin-protein ligase RBX1 | chr22 | Not Cancer Driver | No | 1 | hippie | 10 | 18 | 1 | 1 | 0 |
| RNASE7 | RNASE7 | Q9H1E1 | Ribonuclease 7 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 42 | 4 | 4 | 0 |
| SAMM50 | SAMM50 | Q9Y512 | Sorting and assembly machinery component 50 homolog | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 34 | 1 | 1 | 0 |
| SBSN | SBSN | Q6UWP8 | Suprabasin | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 82 | 552 | 74 | 74 | 0 |
| SDE2 | SDE2 | Q6IQ49 | Replication stress response regulator SDE2 | chr1 | Not Cancer Driver | No | 1 | hippie | 56 | 290 | 35 | 35 | 0 |
| SERPINA12 | SERPINA12 | Q8IW75 | Serpin A12 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 90 | 22 | 3 | 3 | 0 |
| SFN | SFN | P31947 | 14-3-3 protein sigma | chr1 | Not Cancer Driver | No | 1 | hippie | 27 | 75 | 9 | 9 | 0 |
| SHPRH | SHPRH | Q149N8 | E3 ubiquitin-protein ligase SHPRH | chr6 | Not Cancer Driver | No | 1 | hippie | 227 | 359 | 51 | 51 | 0 |
| SLC31A1 | SLC31A1 | O15431 | High affinity copper uptake protein 1 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 22 | 28 | 6 | 6 | 0 |
| SLC9A3R2 | SLC9A3R2 | Q15599 | Na(+)/H(+) exchange regulatory cofactor NHE-RF2 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 328 | 26 | 26 | 0 |
| TCEAL1_ENST00000372626 | TCEAL1 | Q15170 | Transcription elongation factor A protein-like 1 | chrX | Not Cancer Driver | No | 3 | hippie, biogrid | 18 | 147 | 18 | 18 | 0 |
| TDG | TDG | Q13569 | G/T mismatch-specific thymine DNA glycosylase | chr12 | Not Cancer Driver | No | 1 | hippie | 75 | 185 | 31 | 31 | 0 |
| TOB1 | TOB1 | P50616 | Protein Tob1 | chr17 | Not Cancer Driver | No | 1 | hippie | 35 | 214 | 18 | 18 | 0 |
| TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | Census, Compendium | Yes | 1 | hippie | 2891 | 282 | 1466 | 1466 | 83 |
| TUBG1 | TUBG1 | P23258 | Tubulin gamma-1 chain | chr17 | Not Cancer Driver | No | 1 | hippie | 51 | 44 | 10 | 10 | 3 |
| UBE2D1 | UBE2D1 | P51668 | Ubiquitin-conjugating enzyme E2 D1 | chr10 | Not Cancer Driver | No | 1 | hippie | 13 | 14 | 0 | 0 | 0 |
| UBE2D3_ENST00000394801 | UBE2D3 | P61077 | Ubiquitin-conjugating enzyme E2 D3 | chr4 | Not Cancer Driver | No | 1 | hippie | 21 | 13 | 4 | 4 | 0 |
| UBE2E1 | UBE2E1 | P51965 | Ubiquitin-conjugating enzyme E2 E1 | chr3 | Not Cancer Driver | No | 1 | hippie | 21 | 78 | 10 | 10 | 0 |
| UBE2E2_ENST00000425792 | UBE2E2 | Q96LR5 | Ubiquitin-conjugating enzyme E2 E2 | chr3 | Not Cancer Driver | No | 1 | hippie | 28 | 90 | 15 | 15 | 0 |
| UBE2E3_ENST00000602710 | UBE2E3 | Q969T4 | Ubiquitin-conjugating enzyme E2 E3 | chr2 | Not Cancer Driver | No | 1 | hippie | 34 | 97 | 14 | 14 | 0 |
| UBE2I | UBE2I | P63279 | SUMO-conjugating enzyme UBC9 | chr16 | Not Cancer Driver | No | 1 | intact, hippie | 16 | 16 | 3 | 3 | 0 |
| UBE2M | UBE2M | P61081 | NEDD8-conjugating enzyme Ubc12 | chr19 | Not Cancer Driver | No | 1 | hippie | 30 | 32 | 6 | 6 | 0 |
| UBE2N | UBE2N | P61088 | Ubiquitin-conjugating enzyme E2 N | chr12 | Not Cancer Driver | No | 1 | hippie | 25 | 24 | 3 | 3 | 0 |
| VHL | VHL | P40337 | von Hippel-Lindau disease tumor suppressor | chr3 | Census, Compendium | Yes | 1 | hippie | 142 | 117 | 36 | 36 | 133 |
| WDR5 | WDR5 | P61964 | WD repeat-containing protein 5 | chr9 | Not Cancer Driver | No | 1 | hippie | 30 | 35 | 3 | 3 | 0 |
| YWHAB_ENST00000353703 | YWHAB | P31946 | 14-3-3 protein beta/alpha | chr20 | Not Cancer Driver | No | 1 | hippie | 22 | 109 | 4 | 4 | 0 |
| YWHAE | YWHAE | P62258 | 14-3-3 protein epsilon | chr17 | Census | Yes | 1 | hippie | 32 | 41 | 3 | 3 | 0 |
| YWHAG | YWHAG | P61981 | 14-3-3 protein gamma | chr7 | Not Cancer Driver | No | 1 | hippie | 26 | 77 | 9 | 9 | 2 |
| YWHAH | YWHAH | Q04917 | 14-3-3 protein eta | chr22 | Not Cancer Driver | No | 1 | hippie | 15 | 55 | 3 | 3 | 0 |
| YWHAQ | YWHAQ | P27348 | 14-3-3 protein theta | chr2 | Not Cancer Driver | No | 1 | hippie | 29 | 41 | 6 | 6 | 0 |
| YWHAZ_ENST00000395956 | YWHAZ | P63104 | 14-3-3 protein zeta/delta | chr8 | Not Cancer Driver | No | 1 | hippie | 30 | 81 | 10 | 10 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|