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DR1_ENST00000370267 ,DR1 ,Q01658
  • Uniprot Accession= Q01658
  • Ensembl Transcript= ENST00000370267.1
  • Uniprot Name= DR1
  • Name= Protein Dr1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 30
  • Number of Interaction partner in hippie: 123
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTR6 ACTR6 Q9GZN1 Actin-related protein 6 chr12 Not Cancer Driver No 1 hippie, biogrid 48 17 4 4 0
ANXA8L1 ANXA8L1 Q5VT79 Annexin A8-like protein 1 chr10 Not Cancer Driver No 1 hippie 5 37 0 0 0
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 Not Cancer Driver No 1 hippie, biogrid 34 103 14 14 0
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
ARIH1 ARIH1 Q9Y4X5 E3 ubiquitin-protein ligase ARIH1 chr15 Not Cancer Driver No 1 hippie 46 119 7 7 0
ARPC1B_ENST00000431816 ARPC1B O15143 Actin-related protein 2/3 complex subunit 1B chr7 Not Cancer Driver No 1 hippie 37 34 1 1 0
ASCL4 ASCL4 Q6XD76 Achaete-scute homolog 4 chr12 Not Cancer Driver No 1 hippie 25 78 15 15 0
ATXN7_ENST00000487717 ATXN7 O15265 Ataxin-7 chr3 Not Cancer Driver No 1 hippie, biogrid 95 797 82 82 0
AUNIP_ENST00000374298 AUNIP Q9H7T9 Aurora kinase A and ninein-interacting protein chr1 Not Cancer Driver No 1 hippie 23 341 21 21 0
BAG6 BAG6 P46379 Large proline-rich protein BAG6 chr6 Not Cancer Driver No 1 hippie 98 861 79 79 0
BAHD1 BAHD1 Q8TBE0 Bromo adjacent homology domain-containing 1 protein chr15 Not Cancer Driver No 1 hippie 103 618 93 93 0
BMI1 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 1 hippie 50 150 30 30 0
BTF3 BTF3 P20290 Transcription factor BTF3 chr5 Not Cancer Driver No 1 hippie 27 192 24 24 0
BTF3L4 BTF3L4 Q96K17 Transcription factor BTF3 homolog 4 chr1 Not Cancer Driver No 1 hippie 11 131 8 8 0
C14orf93_ENST00000397379 C14orf93 Q9H972 Uncharacterized protein C14orf93 chr14 Not Cancer Driver No 1 hippie 62 375 43 43 0
C16orf87 C16orf87 Q6PH81 UPF0547 protein C16orf87 chr16 Not Cancer Driver No 1 hippie, biogrid 17 103 8 8 0
C8orf48 C8orf48 Q96LL4 Uncharacterized protein C8orf48 chr8 Not Cancer Driver No 1 hippie 26 150 15 15 0
CBLB CBLB Q13191 E3 ubiquitin-protein ligase CBL-B chr3 Census Yes 1 hippie 160 562 104 104 0
CENPA CENPA P49450 Histone H3-like centromeric protein A chr2 Not Cancer Driver No 1 hippie, biogrid 15 50 4 4 0
CEP162 CEP162 Q5TB80 Centrosomal protein of 162 kDa chr6 Not Cancer Driver No 1 hippie 162 1056 128 128 0
CFAP100 CFAP100 Q494V2 Cilia- and flagella-associated protein 100 chr3 Not Cancer Driver No 1 hippie 115 438 89 89 0
CIT_ENST00000261833 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie 284 1017 160 160 3
COPS3 COPS3 Q9UNS2 COP9 signalosome complex subunit 3 chr17 Not Cancer Driver No 1 hippie, biogrid 55 67 10 10 0
CREB1_ENST00000430624 CREB1 P16220 Cyclic AMP-responsive element-binding protein 1 chr2 Census Yes 1 hippie, biogrid 25 277 23 23 0
CSNK1D CSNK1D P48730 Casein kinase I isoform delta chr17 Not Cancer Driver No 1 hippie 59 132 16 16 2
DBNL_ENST00000448521 DBNL Q9UJU6 Drebrin-like protein chr7 Not Cancer Driver No 1 hippie 46 304 31 31 0
DCAF8 DCAF8 Q5TAQ9 DDB1- and CUL4-associated factor 8 chr1 Not Cancer Driver No 1 hippie 85 273 55 55 1
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 Not Cancer Driver No 1 hippie 118 61 10 10 2
DMAP1_ENST00000315913 DMAP1 Q9NPF5 DNA methyltransferase 1-associated protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 49 269 28 28 0
DNMT3L_ENST00000628202 DNMT3L Q9UJW3 DNA (cytosine-5)-methyltransferase 3-like chr21 Not Cancer Driver No 1 hippie 83 10 1 1 0
DPF1_ENST00000456296 DPF1 Q92782 Zinc finger protein neuro-d4 chr19 Not Cancer Driver No 1 hippie 32 85 7 7 0
DPP9_ENST00000598800 DPP9 Q86TI2 Dipeptidyl peptidase 9 chr19 Not Cancer Driver No 1 hippie 94 83 15 15 0
DR1_ENST00000370267 DR1 Q01658 Protein Dr1 chr1 Not Cancer Driver No 1 hippie 21 84 12 12 0
DRAP1 DRAP1 Q14919 Dr1-associated corepressor chr11 Not Cancer Driver No 4 hippie, biogrid 28 170 22 22 0
DYRK2 DYRK2 Q92630 Dual specificity tyrosine-phosphorylation-regulated kinase 2 chr12 Not Cancer Driver No 1 hippie 77 294 39 39 0
EDC4 EDC4 Q6P2E9 Enhancer of mRNA-decapping protein 4 chr16 Not Cancer Driver No 1 hippie, biogrid 144 702 69 69 0
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
EMILIN1 EMILIN1 Q9Y6C2 EMILIN-1 chr2 Not Cancer Driver No 1 hippie 125 669 69 69 0
FAM117B FAM117B Q6P1L5 Protein FAM117B chr2 Not Cancer Driver No 1 hippie 61 547 55 55 0
FAM98C FAM98C Q17RN3 Protein FAM98C chr19 Not Cancer Driver No 1 hippie 48 93 19 19 0
FAM9A_ENST00000381003 FAM9A Q8IZU1 Protein FAM9A chrX Not Cancer Driver No 1 hippie 77 332 77 77 0
GK GK P32189 Glycerol kinase chrX Not Cancer Driver No 1 hippie, biogrid 85 15 3 3 3
GMPPA_ENST00000313597 GMPPA Q96IJ6 Mannose-1-phosphate guanyltransferase alpha chr2 Not Cancer Driver No 1 hippie 53 59 16 16 5
GOPC GOPC Q9HD26 Golgi-associated PDZ and coiled-coil motif-containing protein chr6 Census Yes 1 hippie 56 263 34 34 0
GPSM3_ENST00000375043 GPSM3 Q9Y4H4 G-protein-signaling modulator 3 chr6 Not Cancer Driver No 1 hippie 26 160 26 26 0
HES4_ENST00000304952 HES4 Q9HCC6 Transcription factor HES-4 chr1 Not Cancer Driver No 1 hippie 5 124 3 3 0
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 Not Cancer Driver No 1 hippie 59 335 37 37 0
IK IK Q13123 Protein Red chr5 Not Cancer Driver No 1 hippie 61 482 50 50 0
IPO11_ENST00000325324 IPO11 Q9UI26 Importin-11 chr5 Not Cancer Driver No 1 hippie 82 66 4 4 0
JADE3_ENST00000611250 JADE3 Q92613 Protein Jade-3 chrX Not Cancer Driver No 1 hippie 110 421 52 52 0
KAT14 KAT14 Q9H8E8 Cysteine-rich protein 2-binding protein chr20 Not Cancer Driver No 1 hippie 123 343 57 57 0
KAT2A KAT2A Q92830 Histone acetyltransferase KAT2A chr17 Not Cancer Driver No 3 hippie, biogrid 88 251 17 17 0
KAT2B KAT2B Q92831 Histone acetyltransferase KAT2B chr3 Not Cancer Driver No 3 hippie, biogrid 107 266 27 27 0
KLF15 KLF15 Q9UIH9 Krueppel-like factor 15 chr3 Not Cancer Driver No 1 hippie 66 273 48 48 0
LARP4B LARP4B Q92615 La-related protein 4B chr10 Census Yes 1 hippie 127 521 91 91 0
LPIN1_ENST00000256720 LPIN1 Q14693 Phosphatidate phosphatase LPIN1 chr2 Not Cancer Driver No 1 hippie 120 447 70 70 0
LRSAM1_ENST00000373322 LRSAM1 Q6UWE0 E3 ubiquitin-protein ligase LRSAM1 chr9 Not Cancer Driver No 1 hippie 86 240 30 30 1
MAGEC3 MAGEC3 Q8TD91 Melanoma-associated antigen C3 chrX Not Cancer Driver No 1 hippie 236 181 60 60 0
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 Not Cancer Driver No 1 hippie 104 333 66 66 6
MBIP MBIP Q9NS73 MAP3K12-binding inhibitory protein 1 chr14 Not Cancer Driver No 4 hippie, biogrid 47 190 20 20 0
METTL1 METTL1 Q9UBP6 tRNA (guanine-N(7)-)-methyltransferase chr12 Not Cancer Driver No 1 hippie 43 89 11 11 0
MIER1_ENST00000355356 MIER1 Q8N108 Mesoderm induction early response protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 64 373 45 45 0
MKRN2 MKRN2 Q9H000 E3 ubiquitin-protein ligase makorin-2 chr3 Not Cancer Driver No 1 hippie 45 145 16 16 0
MLC1 MLC1 Q15049 Membrane protein MLC1 chr22 Not Cancer Driver No 1 hippie 53 35 7 7 15
MPC2 MPC2 O95563 Mitochondrial pyruvate carrier 2 chr1 Not Cancer Driver No 1 hippie 13 0 0 0 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
NFIL3 NFIL3 Q16649 Nuclear factor interleukin-3-regulated protein chr9 Not Cancer Driver No 1 hippie 57 333 41 41 0
NFYC NFYC Q13952 Nuclear transcription factor Y subunit gamma chr1 Not Cancer Driver No 2 hippie, biogrid 46 320 32 32 0
NPLOC4 NPLOC4 Q8TAT6 Nuclear protein localization protein 4 homolog chr17 Not Cancer Driver No 1 hippie 78 47 8 8 0
NVL NVL O15381 Nuclear valosin-containing protein-like chr1 Not Cancer Driver No 1 hippie 90 267 31 31 0
PARD6B PARD6B Q9BYG5 Partitioning defective 6 homolog beta chr20 Not Cancer Driver No 1 hippie 50 166 23 23 0
PBX4 PBX4 Q9BYU1 Pre-B-cell leukemia transcription factor 4 chr19 Not Cancer Driver No 1 hippie 47 262 26 26 0
PHF19_ENST00000373896 PHF19 Q5T6S3 PHD finger protein 19 chr9 Not Cancer Driver No 1 hippie 66 129 19 19 0
POLE3 POLE3 Q9NRF9 DNA polymerase epsilon subunit 3 chr9 Not Cancer Driver No 1 hippie 11 117 9 9 0
POLR2E POLR2E P19388 DNA-directed RNA polymerases I, II, and III subunit RPABC1 chr19 Not Cancer Driver No 1 hippie 31 36 3 3 0
PRMT1 PRMT1 Q99873 Protein arginine N-methyltransferase 1 chr19 Not Cancer Driver No 1 hippie 50 18 1 1 0
PSMC3_ENST00000298852 PSMC3 P17980 26S proteasome regulatory subunit 6A chr11 Not Cancer Driver No 1 hippie, biogrid 55 131 10 10 0
RAI2 RAI2 Q9Y5P3 Retinoic acid-induced protein 2 chrX Not Cancer Driver No 1 hippie 105 385 76 76 0
RNF183_ENST00000297894 RNF183 Q96D59 E3 ubiquitin-protein ligase RNF183 chr9 Not Cancer Driver No 1 hippie 22 29 1 1 0
RNF34_ENST00000361234 RNF34 Q969K3 E3 ubiquitin-protein ligase RNF34 chr12 Not Cancer Driver No 1 hippie 30 112 7 7 0
RPP25 RPP25 Q9BUL9 Ribonuclease P protein subunit p25 chr15 Not Cancer Driver No 1 hippie 11 162 11 11 0
RPS4X RPS4X P62701 40S ribosomal protein S4, X isoform chrX Not Cancer Driver No 1 hippie 32 35 6 6 0
RUSC1 RUSC1 Q9BVN2 AP-4 complex accessory subunit RUSC1 chr1 Not Cancer Driver No 1 hippie 99 640 69 69 0
RYBP RYBP Q8N488 RING1 and YY1-binding protein chr3 Not Cancer Driver No 1 hippie 37 214 37 37 0
SAP30 SAP30 O75446 Histone deacetylase complex subunit SAP30 chr4 Not Cancer Driver No 1 hippie 26 123 17 17 0
SEM1_ENST00000356686 SEM1 Q6ZVN7 Putative protein SEM1, isoform 2 chr7 Not Cancer Driver No 1 hippie 2 52 1 1 0
SGF29 SGF29 Q96ES7 SAGA-associated factor 29 chr16 Not Cancer Driver No 1 hippie 31 131 17 17 0
SPATA22_ENST00000397168 SPATA22 Q8NHS9 Spermatogenesis-associated protein 22 chr17 Not Cancer Driver No 1 hippie 71 220 40 40 0
SPPL2B SPPL2B Q8TCT7 Signal peptide peptidase-like 2B chr19 Not Cancer Driver No 1 hippie 68 99 17 17 0
SRCAP SRCAP Q6ZRS2 Helicase SRCAP chr16 Not Cancer Driver No 1 hippie, biogrid 438 2534 340 340 0
STRN4_ENST00000263280 STRN4 Q9NRL3 Striatin-4 chr19 Not Cancer Driver No 1 hippie 84 407 40 40 0
SUPT20H_ENST00000350612 SUPT20H Q8NEM7 Transcription factor SPT20 homolog chr13 Not Cancer Driver No 2 hippie, biogrid 93 426 56 56 0
SUPT3H_ENST00000371459 SUPT3H O75486 Transcription initiation protein SPT3 homolog chr6 Not Cancer Driver No 1 hippie, biogrid 49 49 4 4 0
SUPT7L SUPT7L O94864 STAGA complex 65 subunit gamma chr2 Not Cancer Driver No 1 hippie, biogrid 41 281 30 30 0
SYNCRIP SYNCRIP O60506 Heterogeneous nuclear ribonucleoprotein Q chr6 Not Cancer Driver No 1 hippie 93 285 39 39 0
TACO1 TACO1 Q9BSH4 Translational activator of cytochrome c oxidase 1 chr17 Not Cancer Driver No 1 hippie 21 111 2 2 0
TADA1 TADA1 Q96BN2 Transcriptional adapter 1 chr1 Not Cancer Driver No 1 hippie, biogrid 38 116 12 12 0
TADA2B TADA2B Q86TJ2 Transcriptional adapter 2-beta chr4 Not Cancer Driver No 2 hippie, biogrid 55 128 19 19 0
TADA3 TADA3 O75528 Transcriptional adapter 3 chr3 Not Cancer Driver No 4 hippie, biogrid 54 353 43 43 0
TAF10 TAF10 Q12962 Transcription initiation factor TFIID subunit 10 chr11 Not Cancer Driver No 1 hippie, biogrid 17 131 4 4 0
TAF9 TAF9 Q16594 Transcription initiation factor TFIID subunit 9 chr5 Not Cancer Driver No 1 hippie, biogrid 25 203 19 19 0
TAF9B TAF9B Q9HBM6 Transcription initiation factor TFIID subunit 9B chrX Not Cancer Driver No 1 hippie, biogrid 48 189 34 34 0
TBP TBP P20226 TATA-box-binding protein chr6 Not Cancer Driver No 1 hippie 40 164 14 14 0
THEG THEG Q9P2T0 Testicular haploid expressed gene protein chr19 Not Cancer Driver No 1 hippie 84 238 62 62 0
TIMM44 TIMM44 O43615 Mitochondrial import inner membrane translocase subunit TIM44 chr19 Not Cancer Driver No 1 hippie 56 175 22 22 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TRRAP TRRAP Q9Y4A5 Transformation/transcription domain-associated protein chr7 Census, Compendium Yes 1 hippie, biogrid 554 402 59 59 8
TTF2 TTF2 Q9UNY4 Transcription termination factor 2 chr1 Not Cancer Driver No 1 hippie 118 550 50 50 0
TTLL12 TTLL12 Q14166 Tubulin--tyrosine ligase-like protein 12 chr22 Not Cancer Driver No 1 hippie 69 100 6 6 0
UBE3A UBE3A Q05086 Ubiquitin-protein ligase E3A chr15 Not Cancer Driver No 1 hippie 141 136 22 22 0
USP2 USP2 O75604 Ubiquitin carboxyl-terminal hydrolase 2 chr11 Not Cancer Driver No 1 hippie 88 213 39 39 0
VHL VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 Census, Compendium Yes 1 hippie 142 117 36 36 133
VSX2 VSX2 P58304 Visual system homeobox 2 chr14 Not Cancer Driver No 1 hippie 43 268 23 23 5
WDR5 WDR5 P61964 WD repeat-containing protein 5 chr9 Not Cancer Driver No 4 hippie, biogrid 30 35 3 3 0
XPO1_ENST00000406957 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie 140 33 9 9 0
YEATS2 YEATS2 Q9ULM3 YEATS domain-containing protein 2 chr3 Not Cancer Driver No 3 hippie, biogrid 170 983 124 124 0
ZC2HC1C ZC2HC1C Q53FD0 Zinc finger C2HC domain-containing protein 1C chr14 Not Cancer Driver No 1 hippie 39 395 32 32 0
ZDHHC17 ZDHHC17 Q8IUH5 Palmitoyltransferase ZDHHC17 chr12 Not Cancer Driver No 1 hippie 84 49 9 9 0
ZNF219 ZNF219 Q9P2Y4 Zinc finger protein 219 chr14 Not Cancer Driver No 1 hippie 44 628 37 37 0
ZNF581 ZNF581 Q9P0T4 Zinc finger protein 581 chr19 Not Cancer Driver No 1 hippie 26 96 9 9 0
ZNF829_ENST00000391711 ZNF829 Q3KNS6 Zinc finger protein 829 chr19 Not Cancer Driver No 1 hippie 83 57 19 19 0
ZSCAN1 ZSCAN1 Q8NBB4 Zinc finger and SCAN domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 132 298 98 98 0
ZSCAN22 ZSCAN22 P10073 Zinc finger and SCAN domain-containing protein 22 chr19 Not Cancer Driver No 1 hippie 81 250 35 35 0