Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ACTC1 | ACTC1 | P68032 | Actin, alpha cardiac muscle 1 | chr15 | Not Cancer Driver | No | 1 | hippie | 114 | 48 | 19 | 19 | 11 |
AKT3_ENST00000366539 | AKT3 | Q9Y243 | RAC-gamma serine/threonine-protein kinase | chr1 | Census, Compendium | Yes | 1 | intact, hippie | 92 | 131 | 24 | 24 | 3 |
ANK3 | ANK3 | Q12955 | Ankyrin-3 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 860 | 3054 | 579 | 579 | 0 |
ANXA7 | ANXA7 | P20073 | Annexin A7 | chr10 | Not Cancer Driver | No | 1 | intact, hippie | 68 | 215 | 37 | 37 | 0 |
API5 | API5 | Q9BZZ5 | Apoptosis inhibitor 5 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 65 | 92 | 10 | 10 | 0 |
APP | APP | P05067 | Amyloid-beta precursor protein | chr21 | Not Cancer Driver | No | 1 | intact, hippie | 128 | 418 | 71 | 71 | 17 |
ARF6 | ARF6 | P62330 | ADP-ribosylation factor 6 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 5 | 0 | 0 | 0 |
ARHGAP30 | ARHGAP30 | Q7Z6I6 | Rho GTPase-activating protein 30 | chr1 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 199 | 854 | 151 | 151 | 0 |
ARPC3 | ARPC3 | O15145 | Actin-related protein 2/3 complex subunit 3 | chr12 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 17 | 26 | 6 | 6 | 0 |
AURKB_ENST00000585124 | AURKB | Q96GD4 | Aurora kinase B | chr17 | Not Cancer Driver | No | 1 | hippie | 51 | 63 | 8 | 8 | 0 |
AVIL | AVIL | O75366 | Advillin | chr12 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 91 | 138 | 17 | 17 | 2 |
BAG2 | BAG2 | O95816 | BAG family molecular chaperone regulator 2 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 17 | 112 | 9 | 9 | 0 |
BAG5_ENST00000299204 | BAG5 | Q9UL15 | BAG family molecular chaperone regulator 5 | chr14 | Not Cancer Driver | No | 1 | hippie | 37 | 63 | 7 | 7 | 0 |
BCL2L1 | BCL2L1 | Q07817 | Bcl-2-like protein 1 | chr20 | Not Cancer Driver | No | 1 | intact, hippie | 29 | 55 | 3 | 3 | 0 |
BCL2L14 | BCL2L14 | Q9BZR8 | Apoptosis facilitator Bcl-2-like protein 14 | chr12 | Not Cancer Driver | No | 1 | hippie | 29 | 40 | 4 | 4 | 0 |
BMI1 | BMI1 | P35226 | Polycomb complex protein BMI-1 | chr10 | Not Cancer Driver | No | 1 | intact, hippie | 50 | 150 | 30 | 30 | 0 |
C11orf52 | C11orf52 | Q96A22 | Uncharacterized protein C11orf52 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 108 | 12 | 12 | 0 |
CALM1 | CALM1 | P0DP23 | Calmodulin-1 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 19 | 115 | 15 | 15 | 7 |
CAMK2D_ENST00000342666 | CAMK2D | Q13557 | Calcium/calmodulin-dependent protein kinase type II subunit delta | chr4 | Not Cancer Driver | No | 1 | hippie | 57 | 84 | 10 | 10 | 0 |
CAPN10 | CAPN10 | Q9HC96 | Calpain-10 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 87 | 52 | 6 | 6 | 0 |
CAPN12 | CAPN12 | Q6ZSI9 | Calpain-12 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 83 | 62 | 9 | 9 | 0 |
CAPN2 | CAPN2 | P17655 | Calpain-2 catalytic subunit | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 81 | 46 | 11 | 11 | 0 |
CAPZA2 | CAPZA2 | P47755 | F-actin-capping protein subunit alpha-2 | chr7 | Not Cancer Driver | No | 1 | hippie | 37 | 19 | 0 | 0 | 0 |
CBY1_ENST00000216029 | CBY1 | Q9Y3M2 | Protein chibby homolog 1 | chr22 | Not Cancer Driver | No | 2 | intact, hippie | 13 | 98 | 11 | 11 | 0 |
CCDC8 | CCDC8 | Q9H0W5 | Coiled-coil domain-containing protein 8 | chr19 | Not Cancer Driver | No | 1 | hippie | 96 | 505 | 91 | 91 | 0 |
CCNB1 | CCNB1 | P14635 | G2/mitotic-specific cyclin-B1 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 49 | 145 | 14 | 14 | 0 |
CCT8L2 | CCT8L2 | Q96SF2 | T-complex protein 1 subunit theta-like 2 | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 216 | 104 | 46 | 46 | 0 |
CDC42_ENST00000344548 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | Not Cancer Driver | No | 1 | hippie | 39 | 23 | 2 | 2 | 1 |
CDK2 | CDK2 | P24941 | Cyclin-dependent kinase 2 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 24 | 0 | 0 | 0 | 0 |
CDKN1A_ENST00000373711 | CDKN1A | P38936 | Cyclin-dependent kinase inhibitor 1 | chr6 | Census, Compendium | Yes | 1 | intact, hippie | 48 | 121 | 30 | 30 | 0 |
CEP250 | CEP250 | Q9BV73 | Centrosome-associated protein CEP250 | chr20 | Not Cancer Driver | No | 1 | hippie | 250 | 1859 | 195 | 195 | 0 |
CFTR | CFTR | P13569 | Cystic fibrosis transmembrane conductance regulator | chr7 | Not Cancer Driver | No | 2 | intact, hippie | 287 | 145 | 18 | 18 | 151 |
CIAO2A | CIAO2A | Q9H5X1 | Cytosolic iron-sulfur assembly component 2A | chr15 | Not Cancer Driver | No | 1 | hippie | 24 | 28 | 4 | 4 | 0 |
CIB2 | CIB2 | O75838 | Calcium and integrin-binding family member 2 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 7 | 0 | 0 | 5 |
CKB | CKB | P12277 | Creatine kinase B-type | chr14 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 31 | 102 | 4 | 4 | 0 |
COPS5 | COPS5 | Q92905 | COP9 signalosome complex subunit 5 | chr8 | Not Cancer Driver | No | 1 | hippie | 36 | 32 | 7 | 7 | 0 |
CRLF3 | CRLF3 | Q8IUI8 | Cytokine receptor-like factor 3 | chr17 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 46 | 79 | 6 | 6 | 0 |
CSAG1 | CSAG1 | Q6PB30 | Putative chondrosarcoma-associated gene 1 protein | chrX | Not Cancer Driver | No | 1 | intact, hippie | 32 | 70 | 28 | 28 | 0 |
CTBP1 | CTBP1 | Q13363 | C-terminal-binding protein 1 | chr4 | Not Cancer Driver | No | 1 | intact, hippie | 42 | 123 | 9 | 9 | 1 |
CUL4A | CUL4A | Q13619 | Cullin-4A | chr13 | Not Cancer Driver | No | 1 | hippie | 64 | 102 | 2 | 2 | 0 |
D2HGDH | D2HGDH | Q8N465 | D-2-hydroxyglutarate dehydrogenase, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 61 | 46 | 1 | 1 | 0 |
DAPK1_ENST00000622514 | DAPK1 | P53355 | Death-associated protein kinase 1 | chr9 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 193 | 114 | 11 | 11 | 0 |
DCAF4 | DCAF4 | Q8WV16 | DDB1- and CUL4-associated factor 4 | chr14 | Not Cancer Driver | No | 1 | intact, hippie | 59 | 114 | 11 | 11 | 0 |
DCAF7 | DCAF7 | P61962 | DDB1- and CUL4-associated factor 7 | chr17 | Not Cancer Driver | No | 2 | intact, hippie | 48 | 0 | 0 | 0 | 0 |
DISC1_ENST00000439617 | DISC1 | Q9NRI5 | Disrupted in schizophrenia 1 protein | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 132 | 514 | 82 | 82 | 0 |
DOCK6 | DOCK6 | Q96HP0 | Dedicator of cytokinesis protein 6 | chr19 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 203 | 496 | 57 | 57 | 0 |
DOCK8 | DOCK8 | Q8NF50 | Dedicator of cytokinesis protein 8 | chr9 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 321 | 312 | 60 | 60 | 1 |
DUSP13_ENST00000472493 | DUSP13 | Q9UII6 | Dual specificity protein phosphatase 13 isoform B | chr10 | Not Cancer Driver | No | 1 | hippie | 45 | 16 | 1 | 1 | 0 |
DUSP26 | DUSP26 | Q9BV47 | Dual specificity protein phosphatase 26 | chr8 | Not Cancer Driver | No | 1 | hippie | 56 | 14 | 6 | 6 | 0 |
DYRK1A_ENST00000644942 | DYRK1A | Q13627 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | chr21 | Not Cancer Driver | No | 1 | hippie | 135 | 447 | 73 | 73 | 0 |
EEF1AKMT3 | EEF1AKMT3 | Q96AZ1 | EEF1A lysine methyltransferase 3 | chr12 | Not Cancer Driver | No | 1 | hippie | 23 | 33 | 1 | 1 | 0 |
EGLN3 | EGLN3 | Q9H6Z9 | Prolyl hydroxylase EGLN3 | chr14 | Not Cancer Driver | No | 1 | hippie | 33 | 13 | 0 | 0 | 0 |
EP300 | EP300 | Q09472 | Histone acetyltransferase p300 | chr22 | Census, Compendium | Yes | 1 | hippie | 334 | 1790 | 196 | 196 | 1 |
ERBB2 | ERBB2 | P04626 | Receptor tyrosine-protein kinase erbB-2 | chr17 | Census, Compendium | Yes | 1 | hippie | 275 | 314 | 41 | 41 | 1 |
ERBB3 | ERBB3 | P21860 | Receptor tyrosine-protein kinase erbB-3 | chr12 | Census, Compendium | Yes | 1 | hippie | 298 | 396 | 70 | 70 | 3 |
ERLEC1 | ERLEC1 | Q96DZ1 | Endoplasmic reticulum lectin 1 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 54 | 134 | 17 | 17 | 0 |
ESR2 | ESR2 | Q92731 | Estrogen receptor beta | chr14 | Not Cancer Driver | No | 1 | hippie | 90 | 92 | 11 | 11 | 1 |
EZR | EZR | P15311 | Ezrin | chr6 | Census | Yes | 1 | intact, hippie | 66 | 295 | 35 | 35 | 0 |
FBXW11 | FBXW11 | Q9UKB1 | F-box/WD repeat-containing protein 11 | chr5 | Not Cancer Driver | No | 1 | hippie | 75 | 20 | 3 | 3 | 7 |
FBXW7_ENST00000603841 | FBXW7 | Q969H0 | F-box/WD repeat-containing protein 7 | chr4 | Census, Compendium | Yes | 1 | hippie | 322 | 230 | 38 | 38 | 0 |
FGD5 | FGD5 | Q6ZNL6 | FYVE, RhoGEF and PH domain-containing protein 5 | chr3 | Compendium | Yes | 1 | hippie, biogrid | 275 | 915 | 180 | 180 | 0 |
GLIPR1 | GLIPR1 | P48060 | Glioma pathogenesis-related protein 1 | chr12 | Not Cancer Driver | No | 1 | hippie | 56 | 0 | 0 | 0 | 0 |
GRB7_ENST00000394209 | GRB7 | Q14451 | Growth factor receptor-bound protein 7 | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 84 | 134 | 27 | 27 | 0 |
GTF2A1 | GTF2A1 | P52655 | Transcription initiation factor IIA subunit 1 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 49 | 260 | 38 | 38 | 0 |
HIF1AN | HIF1AN | Q9NWT6 | Hypoxia-inducible factor 1-alpha inhibitor | chr10 | Not Cancer Driver | No | 1 | hippie | 37 | 77 | 9 | 9 | 0 |
HTRA2 | HTRA2 | O43464 | Serine protease HTRA2, mitochondrial | chr2 | Compendium | Yes | 1 | hippie | 44 | 127 | 9 | 9 | 2 |
IFI16_ENST00000295809 | IFI16 | Q16666 | Gamma-interferon-inducible protein 16 | chr1 | Not Cancer Driver | No | 1 | hippie | 155 | 419 | 90 | 90 | 0 |
IKBKG_ENST00000611071 | IKBKG | Q9Y6K9 | NF-kappa-B essential modulator | chrX | Not Cancer Driver | No | 1 | hippie | 6 | 301 | 6 | 6 | 22 |
IMMP1L | IMMP1L | Q96LU5 | Mitochondrial inner membrane protease subunit 1 | chr11 | Not Cancer Driver | No | 1 | hippie | 20 | 3 | 0 | 0 | 0 |
IMMP2L_ENST00000452895 | IMMP2L | Q96T52 | Mitochondrial inner membrane protease subunit 2 | chr7 | Not Cancer Driver | No | 1 | hippie | 36 | 29 | 7 | 7 | 0 |
IRF3_ENST00000597198 | IRF3 | Q14653 | Interferon regulatory factor 3 | chr19 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 36 | 204 | 21 | 21 | 1 |
ISM2 | ISM2 | Q6H9L7 | Isthmin-2 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 89 | 361 | 65 | 65 | 0 |
KIF14 | KIF14 | Q15058 | Kinesin-like protein KIF14 | chr1 | Not Cancer Driver | No | 1 | hippie | 222 | 774 | 102 | 102 | 2 |
KIF23 | KIF23 | Q02241 | Kinesin-like protein KIF23 | chr15 | Not Cancer Driver | No | 1 | hippie | 102 | 559 | 62 | 62 | 0 |
KLHDC9 | KLHDC9 | Q8NEP7 | Kelch domain-containing protein 9 | chr1 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 21 | 130 | 8 | 8 | 0 |
KRAS | KRAS | P01116 | GTPase KRas | chr12 | Census, Compendium | Yes | 1 | hippie, biogrid | 788 | 7 | 2 | 2 | 27 |
KRT8_ENST00000546897 | KRT8 | P05787 | Keratin, type II cytoskeletal 8 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 65 | 221 | 37 | 37 | 3 |
LDHB_ENST00000350669 | LDHB | P07195 | L-lactate dehydrogenase B chain | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 47 | 15 | 2 | 2 | 11 |
LGR4 | LGR4 | Q9BXB1 | Leucine-rich repeat-containing G-protein coupled receptor 4 | chr11 | Not Cancer Driver | No | 1 | hippie | 108 | 16 | 3 | 3 | 0 |
LPCAT1 | LPCAT1 | Q8NF37 | Lysophosphatidylcholine acyltransferase 1 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 85 | 66 | 11 | 11 | 0 |
LRCH1_ENST00000389798 | LRCH1 | Q9Y2L9 | Leucine-rich repeat and calponin homology domain-containing protein 1 | chr13 | Not Cancer Driver | No | 2 | hippie, biogrid | 95 | 380 | 41 | 41 | 0 |
LRCH2 | LRCH2 | Q5VUJ6 | Leucine-rich repeat and calponin homology domain-containing protein 2 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 128 | 458 | 77 | 77 | 0 |
LRCH3_ENST00000425562 | LRCH3 | Q96II8 | DISP complex protein LRCH3 | chr3 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 101 | 415 | 55 | 55 | 0 |
LRCH4 | LRCH4 | O75427 | Leucine-rich repeat and calponin homology domain-containing protein 4 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 77 | 332 | 42 | 42 | 0 |
LRRC31 | LRRC31 | Q6UY01 | Leucine-rich repeat-containing protein 31 | chr3 | Not Cancer Driver | No | 1 | hippie | 109 | 80 | 10 | 10 | 0 |
LRRK2 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 519 | 90 | 17 | 17 | 23 |
LYN | LYN | P07948 | Tyrosine-protein kinase Lyn | chr8 | Census | Yes | 1 | hippie, biogrid | 95 | 84 | 12 | 12 | 0 |
MALL | MALL | Q13021 | MAL-like protein | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 0 | 0 | 0 | 0 |
MAP1LC3A_ENST00000397709 | MAP1LC3A | Q9H492 | Microtubule-associated proteins 1A/1B light chain 3A | chr20 | Not Cancer Driver | No | 1 | hippie | 22 | 24 | 1 | 1 | 0 |
MAP1LC3B | MAP1LC3B | Q9GZQ8 | Microtubule-associated proteins 1A/1B light chain 3B | chr16 | Not Cancer Driver | No | 1 | intact | 10 | 17 | 1 | 1 | 0 |
MAP2K2 | MAP2K2 | P36507 | Dual specificity mitogen-activated protein kinase kinase 2 | chr19 | Census | Yes | 1 | hippie, biogrid | 58 | 105 | 14 | 14 | 4 |
MARK4 | MARK4 | Q96L34 | MAP/microtubule affinity-regulating kinase 4 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 94 | 403 | 46 | 46 | 0 |
MED23 | MED23 | Q9ULK4 | Mediator of RNA polymerase II transcription subunit 23 | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 158 | 28 | 2 | 2 | 1 |
MKI67 | MKI67 | P46013 | Proliferation marker protein Ki-67 | chr10 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 540 | 3169 | 529 | 529 | 0 |
MLH1 | MLH1 | P40692 | DNA mismatch repair protein Mlh1 | chr3 | Census | Yes | 1 | hippie | 92 | 208 | 22 | 22 | 85 |
MOB1A | MOB1A | Q9H8S9 | MOB kinase activator 1A | chr2 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 16 | 10 | 2 | 2 | 0 |
MOB1B_ENST00000309395 | MOB1B | Q7L9L4 | MOB kinase activator 1B | chr4 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 17 | 7 | 0 | 0 | 0 |
MOV10_ENST00000357443 | MOV10 | Q9HCE1 | Helicase MOV-10 | chr1 | Not Cancer Driver | No | 1 | hippie | 110 | 101 | 8 | 8 | 0 |
MTMR7 | MTMR7 | Q9Y216 | Myotubularin-related protein 7 | chr8 | Not Cancer Driver | No | 1 | hippie | 98 | 160 | 26 | 26 | 0 |
MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | Census, Compendium | Yes | 1 | hippie | 80 | 299 | 46 | 46 | 0 |
MYH9 | MYH9 | P35579 | Myosin-9 | chr22 | Census, Compendium | Yes | 1 | intact, hippie | 310 | 1120 | 160 | 160 | 17 |
MYO1C | MYO1C | O00159 | Unconventional myosin-Ic | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 110 | 66 | 11 | 11 | 0 |
MYO6 | MYO6 | Q9UM54 | Unconventional myosin-VI | chr6 | Not Cancer Driver | No | 1 | hippie | 176 | 342 | 41 | 41 | 3 |
NBEAL2 | NBEAL2 | Q6ZNJ1 | Neurobeachin-like protein 2 | chr3 | Not Cancer Driver | No | 1 | intact, hippie | 295 | 515 | 59 | 59 | 8 |
NOD2 | NOD2 | Q9HC29 | Nucleotide-binding oligomerization domain-containing protein 2 | chr16 | Not Cancer Driver | No | 1 | hippie | 169 | 40 | 4 | 4 | 15 |
NRAS | NRAS | P01111 | GTPase NRas | chr1 | Census, Compendium | Yes | 1 | hippie | 284 | 10 | 0 | 0 | 14 |
NSD3 | NSD3 | Q9BZ95 | Histone-lysine N-methyltransferase NSD3 | chr8 | Census | Yes | 1 | intact, hippie | 164 | 679 | 98 | 98 | 0 |
NTRK1 | NTRK1 | P04629 | High affinity nerve growth factor receptor | chr1 | Census, Compendium | Yes | 1 | hippie | 168 | 57 | 8 | 8 | 25 |
NUP155 | NUP155 | O75694 | Nuclear pore complex protein Nup155 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 154 | 221 | 19 | 19 | 1 |
NUPR1_ENST00000324873 | NUPR1 | O60356 | Nuclear protein 1 | chr16 | Not Cancer Driver | No | 1 | hippie | 10 | 82 | 10 | 10 | 0 |
NXF1_ENST00000294172 | NXF1 | Q9UBU9 | Nuclear RNA export factor 1 | chr11 | Compendium | Yes | 1 | hippie | 100 | 163 | 32 | 32 | 0 |
PAN2_ENST00000548043 | PAN2 | Q504Q3 | PAN2-PAN3 deadenylation complex catalytic subunit PAN2 | chr12 | Not Cancer Driver | No | 1 | hippie | 139 | 78 | 10 | 10 | 0 |
PDIA4 | PDIA4 | P13667 | Protein disulfide-isomerase A4 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 81 | 147 | 22 | 22 | 0 |
PFN1 | PFN1 | P07737 | Profilin-1 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 7 | 1 | 1 | 3 |
PIH1D1 | PIH1D1 | Q9NWS0 | PIH1 domain-containing protein 1 | chr19 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 30 | 157 | 13 | 13 | 0 |
PLK4 | PLK4 | O00444 | Serine/threonine-protein kinase PLK4 | chr4 | Not Cancer Driver | No | 1 | hippie | 102 | 451 | 45 | 45 | 0 |
PPP1R18_ENST00000615527 | PPP1R18 | Q6NYC8 | Phostensin | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 585 | 49 | 49 | 0 |
PPP2CB | PPP2CB | P62714 | Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform | chr8 | Not Cancer Driver | No | 1 | intact, hippie | 37 | 12 | 0 | 0 | 0 |
PPT1 | PPT1 | P50897 | Palmitoyl-protein thioesterase 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 37 | 0 | 0 | 0 | 23 |
PRKCSH_ENST00000589838 | PRKCSH | P14314 | Glucosidase 2 subunit beta | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 68 | 320 | 41 | 41 | 0 |
PRNP | PRNP | P04156 | Major prion protein | chr20 | Not Cancer Driver | No | 1 | hippie | 36 | 115 | 7 | 7 | 18 |
PRPSAP2 | PRPSAP2 | O60256 | Phosphoribosyl pyrophosphate synthase-associated protein 2 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 54 | 19 | 3 | 3 | 0 |
PSME1_ENST00000206451 | PSME1 | Q06323 | Proteasome activator complex subunit 1 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 80 | 8 | 8 | 0 |
PTGER3_ENST00000370931 | PTGER3 | P43115 | Prostaglandin E2 receptor EP3 subtype | chr1 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 79 | 17 | 2 | 2 | 0 |
PTP4A3_ENST00000521578 | PTP4A3 | O75365 | Protein tyrosine phosphatase type IVA 3 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 30 | 3 | 0 | 0 | 0 |
PUDP_ENST00000381077 | PUDP | Q08623 | Pseudouridine-5'-phosphatase | chrX | Not Cancer Driver | No | 1 | hippie | 45 | 9 | 1 | 1 | 0 |
RAB35 | RAB35 | Q15286 | Ras-related protein Rab-35 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 25 | 2 | 2 | 0 |
RAC1_ENST00000348035 | RAC1 | P63000 | Ras-related C3 botulinum toxin substrate 1 | chr7 | Census, Compendium | Yes | 1 | hippie | 66 | 2 | 1 | 1 | 6 |
RASSF10 | RASSF10 | A6NK89 | Ras association domain-containing protein 10 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 11 | 372 | 8 | 8 | 0 |
RBBP7_ENST00000380087 | RBBP7 | Q16576 | Histone-binding protein RBBP7 | chrX | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 67 | 138 | 19 | 19 | 0 |
RBX1 | RBX1 | P62877 | E3 ubiquitin-protein ligase RBX1 | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 10 | 18 | 1 | 1 | 0 |
RHOA | RHOA | P61586 | Transforming protein RhoA | chr3 | Census, Compendium | Yes | 1 | hippie | 99 | 46 | 13 | 13 | 2 |
RHOB | RHOB | P62745 | Rho-related GTP-binding protein RhoB | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 52 | 19 | 2 | 2 | 0 |
RHOD | RHOD | O00212 | Rho-related GTP-binding protein RhoD | chr11 | Not Cancer Driver | No | 1 | hippie | 20 | 10 | 0 | 0 | 0 |
RHOF | RHOF | Q9HBH0 | Rho-related GTP-binding protein RhoF | chr12 | Not Cancer Driver | No | 1 | hippie | 18 | 10 | 0 | 0 | 0 |
RNF4 | RNF4 | P78317 | E3 ubiquitin-protein ligase RNF4 | chr4 | Not Cancer Driver | No | 1 | hippie | 14 | 117 | 7 | 7 | 0 |
RPP14_ENST00000295959 | RPP14 | O95059 | Ribonuclease P protein subunit p14 | chr3 | Not Cancer Driver | No | 1 | intact, hippie | 8 | 0 | 0 | 0 | 0 |
S100P | S100P | P25815 | Protein S100-P | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 7 | 3 | 1 | 1 | 0 |
SEC16A | SEC16A | O15027 | Protein transport protein Sec16A | chr9 | Not Cancer Driver | No | 1 | hippie | 285 | 1923 | 235 | 235 | 0 |
SIRT7 | SIRT7 | Q9NRC8 | NAD-dependent protein deacetylase sirtuin-7 | chr17 | Not Cancer Driver | No | 1 | hippie | 48 | 163 | 15 | 15 | 0 |
SKAP1_ENST00000584924 | SKAP1 | Q86WV1 | Src kinase-associated phosphoprotein 1 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 130 | 27 | 27 | 0 |
SLITRK2 | SLITRK2 | Q9H156 | SLIT and NTRK-like protein 2 | chrX | Not Cancer Driver | No | 1 | hippie | 276 | 244 | 91 | 91 | 0 |
SMN1_ENST00000503079 | SMN1 | Q16637-2 | Isoform SMN-delta5 of Survival motor neuron protein | chr5 | Not Cancer Driver | No | 1 | intact, hippie | 2 | 181 | 2 | 2 | 0 |
SNCA_ENST00000506244 | SNCA | P37840 | Alpha-synuclein | chr4 | Not Cancer Driver | No | 1 | hippie | 21 | 107 | 13 | 13 | 5 |
SOHLH1_ENST00000298466 | SOHLH1 | Q5JUK2 | Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 48 | 252 | 39 | 39 | 0 |
SOSTDC1 | SOSTDC1 | Q6X4U4 | Sclerostin domain-containing protein 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 22 | 72 | 3 | 3 | 0 |
SOX2 | SOX2 | P48431 | Transcription factor SOX-2 | chr3 | Census | Yes | 1 | hippie | 39 | 312 | 39 | 39 | 0 |
STAU1 | STAU1 | O95793 | Double-stranded RNA-binding protein Staufen homolog 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 77 | 456 | 63 | 63 | 0 |
SULT1C4 | SULT1C4 | O75897 | Sulfotransferase 1C4 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 57 | 19 | 5 | 5 | 0 |
TGM5 | TGM5 | O43548 | Protein-glutamine gamma-glutamyltransferase 5 | chr15 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 120 | 91 | 17 | 17 | 1 |
TK1 | TK1 | P04183 | Thymidine kinase, cytosolic | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 26 | 13 | 4 | 4 | 0 |
TMOD3 | TMOD3 | Q9NYL9 | Tropomodulin-3 | chr15 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 40 | 190 | 24 | 24 | 0 |
TNIP2 | TNIP2 | Q8NFZ5 | TNFAIP3-interacting protein 2 | chr4 | Not Cancer Driver | No | 1 | hippie | 43 | 316 | 36 | 36 | 0 |
TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | Census, Compendium | Yes | 1 | hippie | 2891 | 282 | 1466 | 1466 | 83 |
TRIM37 | TRIM37 | O94972 | E3 ubiquitin-protein ligase TRIM37 | chr17 | Not Cancer Driver | No | 1 | hippie | 119 | 492 | 60 | 60 | 3 |
TRIM55 | TRIM55 | Q9BYV6 | Tripartite motif-containing protein 55 | chr8 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 134 | 276 | 78 | 78 | 0 |
TRIM63 | TRIM63 | Q969Q1 | E3 ubiquitin-protein ligase TRIM63 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 47 | 71 | 13 | 13 | 0 |
TSC1 | TSC1 | Q92574 | Hamartin | chr9 | Census, Compendium | Yes | 1 | hippie | 135 | 732 | 78 | 78 | 11 |
TUBGCP3 | TUBGCP3 | Q96CW5 | Gamma-tubulin complex component 3 | chr13 | Not Cancer Driver | No | 1 | hippie | 109 | 156 | 16 | 16 | 0 |
UBA1 | UBA1 | P22314 | Ubiquitin-like modifier-activating enzyme 1 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 117 | 165 | 22 | 22 | 6 |
UBE2A | UBE2A | P49459 | Ubiquitin-conjugating enzyme E2 A | chrX | Compendium | Yes | 1 | hippie | 35 | 67 | 13 | 13 | 2 |
UBXN6 | UBXN6 | Q9BZV1 | UBX domain-containing protein 6 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 64 | 132 | 26 | 26 | 0 |
UFL1 | UFL1 | O94874 | E3 UFM1-protein ligase 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 109 | 141 | 24 | 24 | 0 |
USP14 | USP14 | P54578 | Ubiquitin carboxyl-terminal hydrolase 14 | chr18 | Not Cancer Driver | No | 1 | hippie | 59 | 86 | 6 | 6 | 0 |
USP19_ENST00000398888 | USP19 | O94966 | Ubiquitin carboxyl-terminal hydrolase 19 | chr3 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 161 | 539 | 68 | 68 | 0 |
USP7 | USP7 | Q93009 | Ubiquitin carboxyl-terminal hydrolase 7 | chr16 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 170 | 215 | 45 | 45 | 0 |
VAC14 | VAC14 | Q08AM6 | Protein VAC14 homolog | chr16 | Not Cancer Driver | No | 1 | hippie | 97 | 116 | 19 | 19 | 3 |
VCP | VCP | P55072 | Transitional endoplasmic reticulum ATPase | chr9 | Not Cancer Driver | No | 1 | hippie | 88 | 186 | 16 | 16 | 16 |
VIRMA | VIRMA | Q69YN4 | Protein virilizer homolog | chr8 | Not Cancer Driver | No | 1 | hippie | 211 | 631 | 93 | 93 | 0 |
WWOX | WWOX | Q9NZC7 | WW domain-containing oxidoreductase | chr16 | Not Cancer Driver | No | 1 | hippie | 79 | 108 | 9 | 9 | 3 |
XPO1_ENST00000406957 | XPO1 | O14980 | Exportin-1 | chr2 | Census, Compendium | Yes | 1 | hippie | 140 | 33 | 9 | 9 | 0 |
YWHAG | YWHAG | P61981 | 14-3-3 protein gamma | chr7 | Not Cancer Driver | No | 1 | intact, hippie | 26 | 77 | 9 | 9 | 2 |
YWHAH | YWHAH | Q04917 | 14-3-3 protein eta | chr22 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 15 | 55 | 3 | 3 | 0 |
YWHAZ_ENST00000395956 | YWHAZ | P63104 | 14-3-3 protein zeta/delta | chr8 | Not Cancer Driver | No | 1 | intact, hippie | 30 | 81 | 10 | 10 | 0 |
ZNF785 | ZNF785 | A8K8V0 | Zinc finger protein 785 | chr16 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 63 | 105 | 13 | 13 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
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