Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACSL3 | ACSL3 | O95573 | Fatty acid CoA ligase Acsl3 | chr2 | Census, Compendium | Yes | 1 | hippie, biogrid | 89 | 47 | 7 | 7 | 0 |
| ADAM30 | ADAM30 | Q9UKF2 | Disintegrin and metalloproteinase domain-containing protein 30 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 133 | 73 | 12 | 12 | 0 |
| ADCY9 | ADCY9 | O60503 | Adenylate cyclase type 9 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 195 | 271 | 42 | 42 | 0 |
| ADGRL2_ENST00000370728 | ADGRL2 | O95490 | Adhesion G protein-coupled receptor L2 | chr1 | Not Cancer Driver | No | 1 | hippie | 373 | 452 | 122 | 122 | 0 |
| ALDH3A2_ENST00000579855 | ALDH3A2 | P51648 | Aldehyde dehydrogenase family 3 member A2 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 47 | 5 | 2 | 2 | 26 |
| ANKLE2 | ANKLE2 | Q86XL3 | Ankyrin repeat and LEM domain-containing protein 2 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 127 | 521 | 71 | 71 | 2 |
| ASIC4_ENST00000358078 | ASIC4 | A0A8I5KPF5 | Acid-sensing ion channel 4 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 121 | 249 | 35 | 35 | 0 |
| ATF6 | ATF6 | P18850 | Cyclic AMP-dependent transcription factor ATF-6 alpha | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 88 | 468 | 59 | 59 | 2 |
| ATF6B | ATF6B | Q99941 | Cyclic AMP-dependent transcription factor ATF-6 beta | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 70 | 557 | 59 | 59 | 0 |
| ATP2A1 | ATP2A1 | O14983 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 157 | 80 | 11 | 11 | 1 |
| ATP2B1_ENST00000261173 | ATP2B1 | P20020 | Plasma membrane calcium-transporting ATPase 1 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 143 | 293 | 42 | 42 | 0 |
| B3GAT1_ENST00000312527 | B3GAT1 | Q9P2W7 | Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 85 | 93 | 32 | 32 | 0 |
| BAG2 | BAG2 | O95816 | BAG family molecular chaperone regulator 2 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 17 | 112 | 9 | 9 | 0 |
| BAG5_ENST00000299204 | BAG5 | Q9UL15 | BAG family molecular chaperone regulator 5 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 63 | 7 | 7 | 0 |
| BCAP31_ENST00000345046 | BCAP31 | P51572 | B-cell receptor-associated protein 31 | chrX | Not Cancer Driver | No | 2 | hippie, biogrid | 37 | 104 | 14 | 14 | 0 |
| BTNL8 | BTNL8 | Q6UX41 | Butyrophilin-like protein 8 | chr5 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 132 | 84 | 22 | 22 | 0 |
| BTNL9 | BTNL9 | Q6UXG8 | Butyrophilin-like protein 9 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 69 | 87 | 4 | 4 | 0 |
| C19orf25 | C19orf25 | Q9UFG5 | UPF0449 protein C19orf25 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 6 | 117 | 6 | 6 | 0 |
| CA14 | CA14 | Q9ULX7 | Carbonic anhydrase 14 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 104 | 14 | 14 | 0 |
| CA9 | CA9 | Q16790 | Carbonic anhydrase 9 | chr9 | Not Cancer Driver | No | 1 | hippie | 72 | 274 | 50 | 50 | 0 |
| CAMLG | CAMLG | P49069 | Guided entry of tail-anchored proteins factor CAMLG | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 32 | 157 | 16 | 16 | 0 |
| CCDC47_ENST00000403162 | CCDC47 | Q96A33 | PAT complex subunit CCDC47 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 49 | 265 | 23 | 23 | 0 |
| CCPG1_ENST00000310958 | CCPG1 | Q9ULG6 | Cell cycle progression protein 1 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 95 | 509 | 64 | 64 | 0 |
| CD3E | CD3E | P07766 | T-cell surface glycoprotein CD3 epsilon chain | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 72 | 12 | 12 | 0 |
| CDHR4 | CDHR4 | A6H8M9 | Cadherin-related family member 4 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 54 | 111 | 4 | 4 | 0 |
| CDKAL1 | CDKAL1 | Q5VV42 | Threonylcarbamoyladenosine tRNA methylthiotransferase | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 80 | 120 | 14 | 14 | 0 |
| CGRRF1 | CGRRF1 | Q99675 | Cell growth regulator with RING finger domain protein 1 | chr14 | Not Cancer Driver | No | 1 | hippie | 31 | 34 | 5 | 5 | 0 |
| CHRNA1_ENST00000348749 | CHRNA1 | P02708 | Acetylcholine receptor subunit alpha | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 86 | 9 | 1 | 1 | 12 |
| CHST8_ENST00000434302 | CHST8 | Q9H2A9 | Carbohydrate sulfotransferase 8 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 105 | 150 | 23 | 23 | 1 |
| CISD2 | CISD2 | Q8N5K1 | CDGSH iron-sulfur domain-containing protein 2 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 11 | 7 | 0 | 0 | 0 |
| CKAP4 | CKAP4 | Q07065 | Cytoskeleton-associated protein 4 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 73 | 409 | 55 | 55 | 0 |
| CLCC1 | CLCC1 | Q96S66 | Chloride channel CLIC-like protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 196 | 19 | 19 | 1 |
| CLEC2B | CLEC2B | Q92478 | C-type lectin domain family 2 member B | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 0 | 0 | 0 | 0 |
| CLEC4A | CLEC4A | Q9UMR7 | C-type lectin domain family 4 member A | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 35 | 22 | 4 | 4 | 0 |
| CNTNAP3 | CNTNAP3 | Q9BZ76 | Contactin-associated protein-like 3 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 181 | 216 | 14 | 14 | 0 |
| COPE_ENST00000262812 | COPE | O14579 | Coatomer subunit epsilon | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 29 | 47 | 6 | 6 | 0 |
| DCAF1 | DCAF1 | Q9Y4B6 | DDB1- and CUL4-associated factor 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 128 | 495 | 44 | 44 | 0 |
| DCT_ENST00000377028 | DCT | P40126 | L-dopachrome tautomerase | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 113 | 19 | 4 | 4 | 2 |
| DDRGK1 | DDRGK1 | Q96HY6 | DDRGK domain-containing protein 1 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 181 | 23 | 23 | 0 |
| DERL1 | DERL1 | Q9BUN8 | Derlin-1 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 11 | 1 | 1 | 0 |
| DHFR2_ENST00000314636 | DHFR2 | Q86XF0 | Dihydrofolate reductase 2, mitochondrial | chr3 | Not Cancer Driver | No | 1 | hippie | 25 | 20 | 0 | 0 | 0 |
| DNAJB1 | DNAJB1 | P25685 | DnaJ homolog subfamily B member 1 | chr19 | Census, Compendium | Yes | 1 | hippie, biogrid | 35 | 196 | 26 | 26 | 0 |
| DNAJC25 | DNAJC25 | Q9H1X3 | DnaJ homolog subfamily C member 25 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 39 | 3 | 3 | 0 |
| DNAJC3 | DNAJC3 | Q13217 | DnaJ homolog subfamily C member 3 | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 60 | 131 | 17 | 17 | 0 |
| DNAJC7 | DNAJC7 | Q99615 | DnaJ homolog subfamily C member 7 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 102 | 9 | 9 | 0 |
| DNMT1_ENST00000340748 | DNMT1 | P26358 | DNA (cytosine-5)-methyltransferase 1 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 203 | 702 | 78 | 78 | 4 |
| DUOXA2 | DUOXA2 | Q1HG44 | Dual oxidase maturation factor 2 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 40 | 0 | 0 | 0 | 0 |
| ECEL1 | ECEL1 | O95672 | Endothelin-converting enzyme-like 1 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 103 | 22 | 2 | 2 | 4 |
| EGFR | EGFR | P00533 | Epidermal growth factor receptor | chr7 | Census, Compendium | Yes | 1 | hippie | 444 | 223 | 35 | 35 | 1 |
| EIF2AK3 | EIF2AK3 | Q9NZJ5 | Eukaryotic translation initiation factor 2-alpha kinase 3 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 149 | 410 | 51 | 51 | 1 |
| ELOVL5_ENST00000304434 | ELOVL5 | Q9NYP7 | Elongation of very long chain fatty acids protein 5 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 25 | 4 | 4 | 2 |
| EMC1 | EMC1 | Q8N766 | ER membrane protein complex subunit 1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 107 | 59 | 6 | 6 | 2 |
| EMC10 | EMC10 | Q5UCC4 | ER membrane protein complex subunit 10 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 109 | 15 | 15 | 0 |
| EMC2 | EMC2 | Q15006 | ER membrane protein complex subunit 2 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 48 | 29 | 3 | 3 | 0 |
| EMC3 | EMC3 | Q9P0I2 | ER membrane protein complex subunit 3 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 31 | 6 | 6 | 0 |
| EMC4 | EMC4 | Q5J8M3 | ER membrane protein complex subunit 4 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 17 | 2 | 2 | 0 |
| EMC7 | EMC7 | Q9NPA0 | ER membrane protein complex subunit 7 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 35 | 54 | 10 | 10 | 0 |
| EMD | EMD | P50402 | Emerin | chrX | Not Cancer Driver | No | 2 | hippie, biogrid | 42 | 160 | 28 | 28 | 4 |
| ENTPD2 | ENTPD2 | Q9Y5L3 | Ectonucleoside triphosphate diphosphohydrolase 2 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 36 | 32 | 0 | 0 | 0 |
| EPHA10 | EPHA10 | Q5JZY3 | Ephrin type-A receptor 10 | chr1 | Not Cancer Driver | No | 1 | intact | 171 | 225 | 41 | 41 | 0 |
| ERGIC2 | ERGIC2 | Q96RQ1 | Endoplasmic reticulum-Golgi intermediate compartment protein 2 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 25 | 2 | 2 | 0 |
| ESR1_ENST00000206249 | ESR1 | P03372 | Estrogen receptor | chr6 | Census, Compendium | Yes | 1 | intact, hippie | 121 | 195 | 27 | 27 | 2 |
| ESR2 | ESR2 | Q92731 | Estrogen receptor beta | chr14 | Not Cancer Driver | No | 1 | hippie | 90 | 92 | 11 | 11 | 1 |
| ESYT1_ENST00000394048 | ESYT1 | Q9BSJ8 | Extended synaptotagmin-1 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 126 | 278 | 32 | 32 | 0 |
| FAF2 | FAF2 | Q96CS3 | FAS-associated factor 2 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 54 | 171 | 16 | 16 | 0 |
| FAR1 | FAR1 | Q8WVX9 | Fatty acyl-CoA reductase 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 66 | 0 | 0 | 0 | 4 |
| FKBP8_ENST00000222308 | FKBP8 | Q14318 | Peptidyl-prolyl cis-trans isomerase FKBP8 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 71 | 160 | 25 | 25 | 0 |
| FNDC3A_ENST00000492622 | FNDC3A | Q9Y2H6 | Fibronectin type-III domain-containing protein 3A | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 121 | 499 | 45 | 45 | 0 |
| GAA_ENST00000390015 | GAA | P10253 | Lysosomal alpha-glucosidase | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 101 | 147 | 18 | 18 | 131 |
| GANAB_ENST00000356638 | GANAB | Q14697 | Neutral alpha-glucosidase AB | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 129 | 132 | 20 | 20 | 3 |
| GJD3 | GJD3 | Q8N144 | Gap junction delta-3 protein | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 5 | 79 | 0 | 0 | 0 |
| GPR45 | GPR45 | Q9Y5Y3 | Probable G-protein coupled receptor 45 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 97 | 0 | 0 | 0 | 0 |
| GPR89B | GPR89B | P0CG08 | Golgi pH regulator B | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 11 | 1 | 0 | 0 | 0 |
| GRAMD1A | GRAMD1A | Q96CP6 | Protein Aster-A | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 83 | 261 | 33 | 33 | 0 |
| GRPEL1 | GRPEL1 | Q9HAV7 | GrpE protein homolog 1, mitochondrial | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 22 | 88 | 7 | 7 | 0 |
| HDGFL2 | HDGFL2 | Q7Z4V5 | Hepatoma-derived growth factor-related protein 2 | chr19 | Not Cancer Driver | No | 1 | hippie | 59 | 622 | 57 | 57 | 0 |
| HLA-B | HLA-B | P01889 | HLA class I histocompatibility antigen, B alpha chain | chr6 | Compendium | Yes | 1 | hippie, biogrid | 78 | 169 | 34 | 34 | 0 |
| HLA-C | HLA-C | P10321 | HLA class I histocompatibility antigen, C alpha chain | chr6 | Not Cancer Driver | No | 2 | hippie, biogrid | 104 | 175 | 58 | 58 | 0 |
| HLA-DQA1 | HLA-DQA1 | A0A173ADG5 | HLA class II histocompatibility antigen DQ alpha chain | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 29 | 5 | 0 | 0 | 0 |
| HLA-E | HLA-E | P13747 | HLA class I histocompatibility antigen, alpha chain E | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 63 | 138 | 39 | 39 | 0 |
| HLA-G_ENST00000360323 | HLA-G | P17693 | HLA class I histocompatibility antigen, alpha chain G | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 94 | 85 | 22 | 22 | 0 |
| HSD17B11 | HSD17B11 | Q8NBQ5 | Estradiol 17-beta-dehydrogenase 11 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 3 | 0 | 0 | 0 |
| HSD3B7 | HSD3B7 | Q9H2F3 | 3 beta-hydroxysteroid dehydrogenase type 7 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 27 | 5 | 5 | 2 |
| HSP90B1 | HSP90B1 | P14625 | Endoplasmin | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 94 | 268 | 35 | 35 | 0 |
| HSPA1A | HSPA1A | P0DMV8 | Heat shock 70 kDa protein 1A | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 200 | 13 | 13 | 0 |
| HSPA2_ENST00000247207 | HSPA2 | P54652 | Heat shock-related 70 kDa protein 2 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 93 | 286 | 38 | 38 | 0 |
| HSPA5 | HSPA5 | P11021 | Endoplasmic reticulum chaperone BiP | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 73 | 282 | 35 | 35 | 0 |
| HSPA8_ENST00000532636 | HSPA8 | P11142 | Heat shock cognate 71 kDa protein | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 149 | 251 | 52 | 52 | 0 |
| HYOU1 | HYOU1 | Q9Y4L1 | Hypoxia up-regulated protein 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 132 | 373 | 47 | 47 | 0 |
| IFT88_ENST00000351808 | IFT88 | Q13099 | Intraflagellar transport protein 88 homolog | chr13 | Not Cancer Driver | No | 1 | intact, hippie | 99 | 280 | 30 | 30 | 0 |
| IGF2R | IGF2R | P11717 | Cation-independent mannose-6-phosphate receptor | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 318 | 255 | 20 | 20 | 0 |
| IL12RB1_ENST00000593993 | IL12RB1 | P42701 | Interleukin-12 receptor subunit beta-1 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 108 | 207 | 38 | 38 | 1 |
| ITM2A | ITM2A | O43736 | Integral membrane protein 2A | chrX | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 75 | 26 | 9 | 9 | 0 |
| ITM2C | ITM2C | Q9NQX7 | Integral membrane protein 2C | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 33 | 4 | 4 | 0 |
| ITPR1_ENST00000354582 | ITPR1 | Q14643 | Inositol 1,4,5-trisphosphate receptor type 1 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 390 | 581 | 76 | 76 | 6 |
| ITPR2 | ITPR2 | Q14571 | Inositol 1,4,5-trisphosphate receptor type 2 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 359 | 394 | 57 | 57 | 1 |
| JPH1 | JPH1 | Q9HDC5 | Junctophilin-1 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 131 | 421 | 89 | 89 | 0 |
| KCNK16_ENST00000373229 | KCNK16 | Q96T55 | Potassium channel subfamily K member 16 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 63 | 14 | 1 | 1 | 0 |
| KLC1_ENST00000348520 | KLC1 | Q07866 | Kinesin light chain 1 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 54 | 292 | 31 | 31 | 0 |
| KRAS | KRAS | P01116 | GTPase KRas | chr12 | Census, Compendium | Yes | 1 | hippie | 788 | 7 | 2 | 2 | 27 |
| KTN1 | KTN1 | Q86UP2 | Kinectin | chr14 | Census | Yes | 1 | hippie, biogrid | 138 | 964 | 102 | 102 | 0 |
| LAMP1 | LAMP1 | P11279 | Lysosome-associated membrane glycoprotein 1 | chr13 | Not Cancer Driver | No | 1 | hippie | 47 | 93 | 10 | 10 | 0 |
| LBR_ENST00000272163 | LBR | Q14739 | Delta(14)-sterol reductase LBR | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 95 | 130 | 15 | 15 | 5 |
| LEMD3 | LEMD3 | Q9Y2U8 | Inner nuclear membrane protein Man1 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 78 | 509 | 33 | 33 | 0 |
| LIFR_ENST00000453190 | LIFR | P42702 | Leukemia inhibitory factor receptor | chr5 | Census, Compendium | Yes | 1 | hippie, biogrid | 247 | 259 | 56 | 56 | 1 |
| LMAN1 | LMAN1 | P49257 | Protein ERGIC-53 | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 63 | 222 | 25 | 25 | 1 |
| LMBR1L | LMBR1L | Q6UX01 | Protein LMBR1L | chr12 | Not Cancer Driver | No | 1 | hippie | 57 | 4 | 0 | 0 | 0 |
| LMNB1 | LMNB1 | P20700 | Lamin-B1 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 60 | 404 | 42 | 42 | 4 |
| LMNB2 | LMNB2 | Q03252 | Lamin-B2 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 428 | 42 | 42 | 5 |
| LNPK_ENST00000272748 | LNPK | Q9C0E8 | Endoplasmic reticulum junction formation protein lunapark | chr2 | Not Cancer Driver | No | 1 | hippie | 62 | 257 | 43 | 43 | 0 |
| LRRC59 | LRRC59 | Q96AG4 | Leucine-rich repeat-containing protein 59 | chr17 | Not Cancer Driver | No | 2 | hippie, biogrid | 33 | 122 | 15 | 15 | 0 |
| LSG1 | LSG1 | Q9H089 | Large subunit GTPase 1 homolog | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 73 | 369 | 42 | 42 | 0 |
| MACO1 | MACO1 | Q8N5G2 | Macoilin | chr1 | Not Cancer Driver | No | 1 | hippie | 79 | 407 | 52 | 52 | 0 |
| MAGT1_ENST00000618282 | MAGT1 | Q9H0U3 | Magnesium transporter protein 1 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 63 | 0 | 0 | 0 | 1 |
| METTL7A_ENST00000332160 | METTL7A | Q9H8H3 | Putative methyltransferase-like protein 7A | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 0 | 0 | 0 | 0 |
| MIA3 | MIA3 | Q5JRA6 | Transport and Golgi organization protein 1 homolog | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 222 | 1490 | 178 | 178 | 0 |
| MTDH | MTDH | Q86UE4 | Protein LYRIC | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 83 | 516 | 81 | 81 | 0 |
| MYBBP1A_ENST00000254718 | MYBBP1A | Q9BQG0 | Myb-binding protein 1A | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 144 | 463 | 47 | 47 | 0 |
| NPC1 | NPC1 | O15118 | NPC intracellular cholesterol transporter 1 | chr18 | Not Cancer Driver | No | 1 | hippie | 155 | 24 | 0 | 0 | 150 |
| NSG2 | NSG2 | Q9Y328 | Neuronal vesicle trafficking-associated protein 2 | chr5 | Not Cancer Driver | No | 1 | hippie | 34 | 43 | 9 | 9 | 0 |
| NTRK3_ENST00000629765 | NTRK3 | Q16288 | NT-3 growth factor receptor | chr15 | Census, Compendium | Yes | 1 | intact | 249 | 57 | 21 | 21 | 0 |
| OSBPL8 | OSBPL8 | Q9BZF1 | Oxysterol-binding protein-related protein 8 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 105 | 401 | 37 | 37 | 0 |
| OTULINL | OTULINL | Q9NUU6 | Inactive ubiquitin thioesterase OTULINL | chr5 | Not Cancer Driver | No | 1 | hippie | 59 | 21 | 0 | 0 | 0 |
| P2RY2_ENST00000393596 | P2RY2 | P41231 | P2Y purinoceptor 2 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 60 | 13 | 13 | 0 |
| P4HB | P4HB | P07237 | Protein disulfide-isomerase | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 61 | 79 | 15 | 15 | 1 |
| PANX1 | PANX1 | Q96RD7 | Pannexin-1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 54 | 45 | 7 | 7 | 2 |
| PCDHB3 | PCDHB3 | Q9Y5E6 | Protocadherin beta-3 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 258 | 119 | 30 | 30 | 0 |
| PDE3B | PDE3B | Q13370 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 135 | 393 | 37 | 37 | 0 |
| PDIA3 | PDIA3 | P30101 | Protein disulfide-isomerase A3 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 57 | 98 | 11 | 11 | 0 |
| PDIA4 | PDIA4 | P13667 | Protein disulfide-isomerase A4 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 81 | 147 | 22 | 22 | 0 |
| PDZD8 | PDZD8 | Q8NEN9 | PDZ domain-containing protein 8 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 126 | 484 | 65 | 65 | 0 |
| PIGU | PIGU | Q9H490 | Phosphatidylinositol glycan anchor biosynthesis class U protein | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 47 | 0 | 0 | 0 | 2 |
| PTPN1 | PTPN1 | P18031 | Tyrosine-protein phosphatase non-receptor type 1 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 49 | 140 | 25 | 25 | 0 |
| PTPN2 | PTPN2 | P17706 | Tyrosine-protein phosphatase non-receptor type 2 | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 57 | 120 | 14 | 14 | 0 |
| PTPRN | PTPRN | Q16849 | Receptor-type tyrosine-protein phosphatase-like N | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 142 | 498 | 73 | 73 | 0 |
| PTPRO | PTPRO | Q16827 | Receptor-type tyrosine-protein phosphatase O | chr12 | Not Cancer Driver | No | 1 | hippie | 204 | 137 | 34 | 34 | 0 |
| PTPRU | PTPRU | Q92729 | Receptor-type tyrosine-protein phosphatase U | chr1 | Not Cancer Driver | No | 1 | hippie | 248 | 325 | 64 | 64 | 0 |
| RAB7A | RAB7A | P51149 | Ras-related protein Rab-7a | chr3 | Not Cancer Driver | No | 1 | biogrid | 27 | 11 | 0 | 0 | 4 |
| RECQL4 | RECQL4 | O94761 | ATP-dependent DNA helicase Q4 | chr8 | Census, Compendium | Yes | 1 | hippie | 138 | 608 | 71 | 71 | 1 |
| RHBDD1 | RHBDD1 | Q8TEB9 | Rhomboid-related protein 4 | chr2 | Not Cancer Driver | No | 1 | hippie | 38 | 69 | 9 | 9 | 0 |
| RPL13A | RPL13A | P40429 | 60S ribosomal protein L13a | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 33 | 2 | 2 | 0 |
| RPL15_ENST00000413699 | RPL15 | P61313 | 60S ribosomal protein L15 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 84 | 9 | 9 | 0 |
| RPL18 | RPL18 | Q07020 | 60S ribosomal protein L18 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 98 | 6 | 6 | 0 |
| RPL27_ENST00000253788 | RPL27 | P61353 | 60S ribosomal protein L27 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 21 | 13 | 3 | 3 | 0 |
| RPL3 | RPL3 | P39023 | 60S ribosomal protein L3 | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 79 | 3 | 3 | 0 |
| RPL4 | RPL4 | P36578 | 60S ribosomal protein L4 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 49 | 222 | 31 | 31 | 0 |
| RPL5_ENST00000370321 | RPL5 | P46777 | 60S ribosomal protein L5 | chr1 | Census | Yes | 1 | hippie, biogrid | 57 | 96 | 17 | 17 | 2 |
| RPL6 | RPL6 | Q02878 | 60S ribosomal protein L6 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 159 | 24 | 24 | 0 |
| RPL7 | RPL7 | P18124 | 60S ribosomal protein L7 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 40 | 4 | 4 | 0 |
| RPL7A | RPL7A | P62424 | 60S ribosomal protein L7a | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 100 | 5 | 5 | 0 |
| RPL8_ENST00000528957 | RPL8 | P62917 | 60S ribosomal protein L8 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 32 | 115 | 17 | 17 | 0 |
| RPLP0_ENST00000228306 | RPLP0 | P05388 | 60S acidic ribosomal protein P0 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 44 | 36 | 4 | 4 | 0 |
| RPLP2_ENST00000530797 | RPLP2 | P05387 | 60S acidic ribosomal protein P2 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 12 | 59 | 5 | 5 | 0 |
| RPN1 | RPN1 | P04843 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 | chr3 | Census | Yes | 2 | hippie, biogrid | 50 | 69 | 3 | 3 | 0 |
| RPN2 | RPN2 | P04844 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 53 | 26 | 4 | 4 | 0 |
| RRBP1_ENST00000246043 | RRBP1 | Q9P2E9 | Ribosome-binding protein 1 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 164 | 1301 | 151 | 151 | 0 |
| RYBP | RYBP | Q8N488 | RING1 and YY1-binding protein | chr3 | Not Cancer Driver | No | 1 | hippie | 37 | 214 | 37 | 37 | 0 |
| SCN4A | SCN4A | P35499 | Sodium channel protein type 4 subunit alpha | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 324 | 372 | 80 | 80 | 60 |
| SCNN1D | SCNN1D | P51172 | Amiloride-sensitive sodium channel subunit delta | chr1 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 56 | 210 | 9 | 9 | 0 |
| SDF2L1 | SDF2L1 | Q9HCN8 | Stromal cell-derived factor 2-like protein 1 | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 130 | 9 | 9 | 0 |
| SEC23IP | SEC23IP | Q9Y6Y8 | SEC23-interacting protein | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 112 | 371 | 40 | 40 | 0 |
| SEC61B | SEC61B | P60468 | Protein transport protein Sec61 subunit beta | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 11 | 60 | 7 | 7 | 0 |
| SEC62 | SEC62 | Q99442 | Translocation protein SEC62 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 211 | 23 | 23 | 0 |
| SEC63 | SEC63 | Q9UGP8 | Translocation protein SEC63 homolog | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 98 | 266 | 37 | 37 | 0 |
| SFTPC | SFTPC | P11686 | Pulmonary surfactant-associated protein C | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 21 | 19 | 2 | 2 | 5 |
| SIDT2_ENST00000620360 | SIDT2 | Q8NBJ9 | SID1 transmembrane family member 2 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 113 | 23 | 6 | 6 | 0 |
| SLC12A2 | SLC12A2 | P55011 | Solute carrier family 12 member 2 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 141 | 297 | 18 | 18 | 8 |
| SLC16A11 | SLC16A11 | Q8NCK7 | Monocarboxylate transporter 11 | chr17 | Not Cancer Driver | No | 1 | hippie | 33 | 72 | 5 | 5 | 0 |
| SLC4A7_ENST00000295736 | SLC4A7 | Q9Y6M7 | Sodium bicarbonate cotransporter 3 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 165 | 406 | 57 | 57 | 0 |
| SMCR8 | SMCR8 | Q8TEV9 | Guanine nucleotide exchange protein SMCR8 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 107 | 357 | 38 | 38 | 0 |
| SMPD4 | SMPD4 | Q9NXE4 | Sphingomyelin phosphodiesterase 4 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 114 | 80 | 12 | 12 | 1 |
| SOAT1 | SOAT1 | P35610 | Sterol O-acyltransferase 1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 73 | 49 | 4 | 4 | 0 |
| SPINT2 | SPINT2 | O43291 | Kunitz-type protease inhibitor 2 | chr19 | Not Cancer Driver | No | 2 | hippie, biogrid | 46 | 25 | 3 | 3 | 1 |
| SRPRA | SRPRA | P08240 | Signal recognition particle receptor subunit alpha | chr11 | Not Cancer Driver | No | 1 | hippie | 95 | 232 | 40 | 40 | 0 |
| SRPRB | SRPRB | Q9Y5M8 | Signal recognition particle receptor subunit beta | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 30 | 23 | 3 | 3 | 0 |
| SSR1 | SSR1 | P43307 | Translocon-associated protein subunit alpha | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 114 | 10 | 10 | 0 |
| ST7 | ST7 | Q9NRC1 | Suppressor of tumorigenicity 7 protein | chr7 | Not Cancer Driver | No | 2 | hippie, biogrid | 62 | 64 | 5 | 5 | 0 |
| ST8SIA3 | ST8SIA3 | O43173 | Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 109 | 0 | 0 | 0 | 0 |
| ST8SIA5_ENST00000315087 | ST8SIA5 | O15466 | Alpha-2,8-sialyltransferase 8E | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 98 | 0 | 0 | 0 | 0 |
| STBD1 | STBD1 | O95210 | Starch-binding domain-containing protein 1 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 47 | 229 | 31 | 31 | 0 |
| STIM1_ENST00000300737 | STIM1 | Q13586 | Stromal interaction molecule 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 70 | 387 | 45 | 45 | 13 |
| STIM2_ENST00000467087 | STIM2 | Q9P246 | Stromal interaction molecule 2 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 82 | 387 | 45 | 45 | 0 |
| STT3B | STT3B | Q8TCJ2 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 60 | 136 | 9 | 9 | 0 |
| STUB1 | STUB1 | Q9UNE7 | E3 ubiquitin-protein ligase CHIP | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 35 | 112 | 14 | 14 | 12 |
| STX5 | STX5 | Q13190 | Syntaxin-5 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 36 | 147 | 14 | 14 | 0 |
| SUN1 | SUN1 | O94901 | SUN domain-containing protein 1 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 109 | 246 | 26 | 26 | 0 |
| SYNE2_ENST00000344113 | SYNE2 | Q8WXH0 | Nesprin-2 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 779 | 1888 | 220 | 220 | 1 |
| SYNE3 | SYNE3 | Q6ZMZ3 | Nesprin-3 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 143 | 236 | 42 | 42 | 0 |
| TAPT1 | TAPT1 | Q6NXT6 | Transmembrane anterior posterior transformation protein 1 homolog | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 47 | 131 | 12 | 12 | 1 |
| TBL2 | TBL2 | Q9Y4P3 | Transducin beta-like protein 2 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 68 | 115 | 13 | 13 | 0 |
| TCTN2 | TCTN2 | Q96GX1 | Tectonic-2 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 75 | 23 | 2 | 2 | 0 |
| TCTN3 | TCTN3 | Q6NUS6 | Tectonic-3 | chr10 | Not Cancer Driver | No | 1 | intact, hippie | 45 | 71 | 8 | 8 | 1 |
| TEX264_ENST00000416589 | TEX264 | Q9Y6I9 | Testis-expressed protein 264 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 40 | 107 | 11 | 11 | 0 |
| TFRC_ENST00000392396 | TFRC | P02786 | Transferrin receptor protein 1 | chr3 | Census | Yes | 1 | hippie, biogrid | 89 | 80 | 6 | 6 | 1 |
| TMEM106A | TMEM106A | Q96A25 | Transmembrane protein 106A | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 9 | 1 | 1 | 0 |
| TMEM199 | TMEM199 | Q8N511 | Transmembrane protein 199 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 54 | 5 | 5 | 3 |
| TMEM30A | TMEM30A | Q9NV96 | Cell cycle control protein 50A | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 76 | 8 | 8 | 0 |
| TNFSF14 | TNFSF14 | O43557 | Tumor necrosis factor ligand superfamily member 14 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 18 | 1 | 1 | 0 |
| TOR1AIP1_ENST00000606911 | TOR1AIP1 | Q5JTV8 | Torsin-1A-interacting protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 71 | 401 | 44 | 44 | 0 |
| TRPM7 | TRPM7 | Q96QT4 | Transient receptor potential cation channel subfamily M member 7 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 199 | 455 | 60 | 60 | 0 |
| TUBA1A | TUBA1A | Q71U36 | Tubulin alpha-1A chain | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 59 | 52 | 11 | 11 | 8 |
| TUBB3 | TUBB3 | Q13509 | Tubulin beta-3 chain | chr16 | Not Cancer Driver | No | 1 | intact, hippie | 67 | 53 | 10 | 10 | 12 |
| UBE2J1 | UBE2J1 | Q9Y385 | Ubiquitin-conjugating enzyme E2 J1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 33 | 158 | 20 | 20 | 0 |
| UBR5 | UBR5 | O95071 | E3 ubiquitin-protein ligase UBR5 | chr8 | Census, Compendium | Yes | 1 | hippie, biogrid | 340 | 1296 | 162 | 162 | 0 |
| UBXN4 | UBXN4 | Q92575 | UBX domain-containing protein 4 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 69 | 302 | 41 | 41 | 0 |
| UGT1A7 | UGT1A7 | Q9HAW7 | UDP-glucuronosyltransferase 1A7 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 110 | 11 | 2 | 2 | 0 |
| USE1 | USE1 | Q9NZ43 | Vesicle transport protein USE1 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 101 | 19 | 19 | 0 |
| VANGL1 | VANGL1 | Q8TAA9 | Vang-like protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 72 | 140 | 15 | 15 | 3 |
| VAPA_ENST00000400000 | VAPA | Q9P0L0 | Vesicle-associated membrane protein-associated protein A | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 184 | 14 | 14 | 0 |
| VAPB | VAPB | O95292 | Vesicle-associated membrane protein-associated protein B/C | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 138 | 8 | 8 | 3 |
| VEZT | VEZT | Q9HBM0 | Vezatin | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 83 | 278 | 22 | 22 | 0 |
| VRK2 | VRK2 | Q86Y07 | Serine/threonine-protein kinase VRK2 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 63 | 126 | 15 | 15 | 0 |
| WDR41 | WDR41 | Q9HAD4 | WD repeat-containing protein 41 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 48 | 23 | 2 | 2 | 0 |
| YKT6 | YKT6 | O15498 | Synaptobrevin homolog YKT6 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 19 | 21 | 2 | 2 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|