Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AIFM1 | AIFM1 | O95831 | Apoptosis-inducing factor 1, mitochondrial | chrX | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 88 | 166 | 22 | 22 | 11 |
| AKAP1_ENST00000539273 | AKAP1 | Q92667 | A-kinase anchor protein 1, mitochondrial | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 107 | 537 | 67 | 67 | 0 |
| AKAP8 | AKAP8 | O43823 | A-kinase anchor protein 8 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 88 | 566 | 78 | 78 | 0 |
| ANXA7 | ANXA7 | P20073 | Annexin A7 | chr10 | Not Cancer Driver | No | 1 | hippie | 68 | 215 | 37 | 37 | 0 |
| APLNR | APLNR | P35414 | Apelin receptor | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 96 | 29 | 8 | 8 | 0 |
| APOO | APOO | Q9BUR5 | MICOS complex subunit MIC26 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 23 | 4 | 4 | 0 |
| APOOL | APOOL | Q6UXV4 | MICOS complex subunit MIC27 | chrX | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 31 | 91 | 8 | 8 | 0 |
| ARHGAP20 | ARHGAP20 | Q9P2F6 | Rho GTPase-activating protein 20 | chr11 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 193 | 607 | 94 | 94 | 0 |
| ARMC1 | ARMC1 | Q9NVT9 | Armadillo repeat-containing protein 1 | chr8 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 34 | 110 | 11 | 11 | 0 |
| ASB14_ENST00000389601 | ASB14 | A6NK59 | Ankyrin repeat and SOCS box protein 14 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 42 | 36 | 0 | 0 | 0 |
| ATAD3A | ATAD3A | Q9NVI7 | ATPase family AAA domain-containing protein 3A | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 66 | 269 | 24 | 24 | 2 |
| ATG2A | ATG2A | Q2TAZ0 | Autophagy-related protein 2 homolog A | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 228 | 887 | 124 | 124 | 0 |
| ATP1B1 | ATP1B1 | P05026 | Sodium/potassium-transporting ATPase subunit beta-1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 38 | 55 | 9 | 9 | 0 |
| ATP5F1A_ENST00000282050 | ATP5F1A | P25705 | ATP synthase subunit alpha, mitochondrial | chr18 | Not Cancer Driver | No | 1 | hippie | 66 | 23 | 5 | 5 | 2 |
| AUH | AUH | Q13825 | Methylglutaconyl-CoA hydratase, mitochondrial | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 29 | 0 | 0 | 1 |
| B3GAT2 | B3GAT2 | Q9NPZ5 | Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 46 | 102 | 10 | 10 | 0 |
| BAG2 | BAG2 | O95816 | BAG family molecular chaperone regulator 2 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 17 | 112 | 9 | 9 | 0 |
| BAG5_ENST00000299204 | BAG5 | Q9UL15 | BAG family molecular chaperone regulator 5 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 63 | 7 | 7 | 0 |
| BBS7 | BBS7 | Q8IWZ6 | Bardet-Biedl syndrome 7 protein | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 99 | 56 | 8 | 8 | 4 |
| BCOR | BCOR | Q6W2J9 | BCL-6 corepressor | chrX | Census, Compendium | Yes | 1 | intact, hippie | 291 | 1285 | 226 | 226 | 1 |
| BIRC3_ENST00000532808 | BIRC3 | Q13489 | Baculoviral IAP repeat-containing protein 3 | chr11 | Census, Compendium | Yes | 1 | hippie | 77 | 98 | 16 | 16 | 0 |
| BMPR1A | BMPR1A | P36894 | Bone morphogenetic protein receptor type-1A | chr10 | Census, Compendium | Yes | 1 | hippie | 66 | 21 | 0 | 0 | 8 |
| BRAF | BRAF | P15056 | Serine/threonine-protein kinase B-raf | chr7 | Census, Compendium | Yes | 1 | hippie | 791 | 310 | 43 | 43 | 39 |
| BSND | BSND | Q8WZ55 | Barttin | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 57 | 209 | 36 | 36 | 4 |
| C19orf70_ENST00000309324 | MICOS13 | Q5XKP0 | MICOS complex subunit MIC13 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 12 | 3 | 0 | 0 | 0 |
| CAPG_ENST00000409724 | CAPG | P40121 | Macrophage-capping protein | chr2 | Not Cancer Driver | No | 1 | hippie | 45 | 95 | 7 | 7 | 0 |
| CD99L2_ENST00000370377 | CD99L2 | Q8TCZ2 | CD99 antigen-like protein 2 | chrX | Not Cancer Driver | No | 1 | hippie | 57 | 193 | 47 | 47 | 0 |
| CHCHD3 | CHCHD3 | Q9NX63 | MICOS complex subunit MIC19 | chr7 | Not Cancer Driver | No | 1 | intact, hippie | 26 | 143 | 16 | 16 | 0 |
| COX14_ENST00000550654 | COX14 | Q96I36 | Cytochrome c oxidase assembly protein COX14 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 4 | 7 | 0 | 0 | 1 |
| COX15 | COX15 | Q7KZN9 | Cytochrome c oxidase assembly protein COX15 homolog | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 48 | 0 | 0 | 0 | 2 |
| COX4I1 | COX4I1 | P13073 | Cytochrome c oxidase subunit 4 isoform 1, mitochondrial | chr16 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 17 | 5 | 1 | 1 | 1 |
| COX6C_ENST00000522940 | COX6C | P09669 | Cytochrome c oxidase subunit 6C | chr8 | Census | Yes | 1 | hippie, biogrid | 14 | 0 | 0 | 0 | 0 |
| CTNNB1_ENST00000643977 | CTNNB1 | P35222 | Catenin beta-1 | chr3 | Census, Compendium | Yes | 1 | hippie, biogrid | 415 | 288 | 301 | 301 | 14 |
| CYBC1_ENST00000577732 | CYBC1 | Q9BQA9 | Cytochrome b-245 chaperone 1 | chr17 | Not Cancer Driver | No | 1 | hippie | 22 | 17 | 2 | 2 | 0 |
| DGCR2 | DGCR2 | P98153 | Integral membrane protein DGCR2/IDD | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 90 | 178 | 24 | 24 | 0 |
| DIABLO | DIABLO | Q9NR28 | Diablo IAP-binding mitochondrial protein | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 62 | 54 | 8 | 8 | 1 |
| DNAJA2 | DNAJA2 | O60884 | DnaJ homolog subfamily A member 2 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 174 | 27 | 27 | 0 |
| DNAJB1 | DNAJB1 | P25685 | DnaJ homolog subfamily B member 1 | chr19 | Census, Compendium | Yes | 1 | hippie, biogrid | 35 | 196 | 26 | 26 | 0 |
| DNAJC7 | DNAJC7 | Q99615 | DnaJ homolog subfamily C member 7 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 102 | 9 | 9 | 0 |
| EEF1D_ENST00000395119 | EEF1D | P29692 | Elongation factor 1-delta | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 40 | 153 | 22 | 22 | 0 |
| EGFR | EGFR | P00533 | Epidermal growth factor receptor | chr7 | Census, Compendium | Yes | 1 | hippie | 444 | 223 | 35 | 35 | 1 |
| EGLN3 | EGLN3 | Q9H6Z9 | Prolyl hydroxylase EGLN3 | chr14 | Not Cancer Driver | No | 1 | hippie | 33 | 13 | 0 | 0 | 0 |
| ELOC | ELOC | Q15369 | Elongin-C | chr8 | Not Cancer Driver | No | 1 | hippie | 22 | 25 | 5 | 5 | 0 |
| EMD | EMD | P50402 | Emerin | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 42 | 160 | 28 | 28 | 4 |
| EMILIN1 | EMILIN1 | Q9Y6C2 | EMILIN-1 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 125 | 669 | 69 | 69 | 0 |
| ERGIC3_ENST00000348547 | ERGIC3 | Q9Y282 | Endoplasmic reticulum-Golgi intermediate compartment protein 3 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 53 | 23 | 3 | 3 | 0 |
| ESR1_ENST00000206249 | ESR1 | P03372 | Estrogen receptor | chr6 | Census, Compendium | Yes | 1 | intact, hippie | 121 | 195 | 27 | 27 | 2 |
| EXD2 | EXD2 | Q9NVH0 | Exonuclease 3'-5' domain-containing protein 2 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 176 | 15 | 15 | 0 |
| FAM174A | FAM174A | Q8TBP5 | Membrane protein FAM174A | chr5 | Not Cancer Driver | No | 2 | hippie, biogrid | 27 | 140 | 21 | 21 | 0 |
| FBXO6 | FBXO6 | Q9NRD1 | F-box only protein 6 | chr1 | Not Cancer Driver | No | 1 | hippie | 31 | 27 | 3 | 3 | 0 |
| FFAR1 | FFAR1 | O14842 | Free fatty acid receptor 1 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 45 | 2 | 0 | 0 | 0 |
| FIS1 | FIS1 | Q9Y3D6 | Mitochondrial fission 1 protein | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 6 | 0 | 0 | 0 |
| FKBP4 | FKBP4 | Q02790 | Peptidyl-prolyl cis-trans isomerase FKBP4 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 46 | 134 | 12 | 12 | 0 |
| FKBP5 | FKBP5 | Q13451 | Peptidyl-prolyl cis-trans isomerase FKBP5 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 70 | 150 | 20 | 20 | 0 |
| FKBP8_ENST00000222308 | FKBP8 | Q14318 | Peptidyl-prolyl cis-trans isomerase FKBP8 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 71 | 160 | 25 | 25 | 0 |
| FTL | FTL | P02792 | Ferritin light chain | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 19 | 36 | 7 | 7 | 2 |
| GAA_ENST00000390015 | GAA | P10253 | Lysosomal alpha-glucosidase | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 101 | 147 | 18 | 18 | 131 |
| GOLT1B | GOLT1B | Q9Y3E0 | Vesicle transport protein GOT1B | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 26 | 0 | 0 | 0 | 0 |
| GP5 | GP5 | P40197 | Platelet glycoprotein V | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 81 | 57 | 5 | 5 | 0 |
| GPA33 | GPA33 | Q99795 | Cell surface A33 antigen | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 68 | 101 | 13 | 13 | 0 |
| GRPEL1 | GRPEL1 | Q9HAV7 | GrpE protein homolog 1, mitochondrial | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 22 | 88 | 7 | 7 | 0 |
| GSTK1_ENST00000358406 | GSTK1 | Q9Y2Q3 | Glutathione S-transferase kappa 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 33 | 30 | 3 | 3 | 0 |
| H3F3A_ENST00000366816 | H3-3B | P84243 | Histone H3.3 | chr1 | Not Cancer Driver | No | 1 | intact | 32 | 51 | 22 | 22 | 3 |
| H3F3B_ENST00000589599 | H3-3B | P84243 | Histone H3.3 | chr17 | Not Cancer Driver | No | 1 | intact | 28 | 51 | 14 | 14 | 3 |
| HADHA | HADHA | P40939 | Trifunctional enzyme subunit alpha, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 72 | 19 | 2 | 2 | 5 |
| HAX1 | HAX1 | O00165 | HCLS1-associated protein X-1 | chr1 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 44 | 219 | 32 | 32 | 2 |
| HDGFL2 | HDGFL2 | Q7Z4V5 | Hepatoma-derived growth factor-related protein 2 | chr19 | Not Cancer Driver | No | 1 | hippie | 59 | 622 | 57 | 57 | 0 |
| HEPACAM2_ENST00000394468 | HEPACAM2 | A8MVW5 | HEPACAM family member 2 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 115 | 50 | 14 | 14 | 0 |
| HIF1AN | HIF1AN | Q9NWT6 | Hypoxia-inducible factor 1-alpha inhibitor | chr10 | Not Cancer Driver | No | 1 | hippie | 37 | 77 | 9 | 9 | 0 |
| HLA-C | HLA-C | P10321 | HLA class I histocompatibility antigen, C alpha chain | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 104 | 175 | 58 | 58 | 0 |
| HNRNPC_ENST00000420743 | HNRNPC | P07910 | Heterogeneous nuclear ribonucleoproteins C1/C2 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 42 | 227 | 35 | 35 | 0 |
| HS2ST1 | HS2ST1 | Q7LGA3 | Heparan sulfate 2-O-sulfotransferase 1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 60 | 44 | 8 | 8 | 3 |
| HSPA1A | HSPA1A | P0DMV8 | Heat shock 70 kDa protein 1A | chr6 | Not Cancer Driver | No | 1 | intact | 24 | 200 | 13 | 13 | 0 |
| HSPA8_ENST00000532636 | HSPA8 | P11142 | Heat shock cognate 71 kDa protein | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 149 | 251 | 52 | 52 | 0 |
| HSPB1 | HSPB1 | P04792 | Heat shock protein beta-1 | chr7 | Not Cancer Driver | No | 1 | hippie | 10 | 118 | 8 | 8 | 20 |
| HTRA2 | HTRA2 | O43464 | Serine protease HTRA2, mitochondrial | chr2 | Compendium | Yes | 1 | hippie | 44 | 127 | 9 | 9 | 2 |
| HTT | HTT | P42858 | Huntingtin | chr4 | Not Cancer Driver | No | 1 | intact, hippie | 336 | 666 | 69 | 69 | 2 |
| IMMP1L | IMMP1L | Q96LU5 | Mitochondrial inner membrane protease subunit 1 | chr11 | Not Cancer Driver | No | 1 | hippie | 20 | 3 | 0 | 0 | 0 |
| IMMT | IMMT | Q16891 | MICOS complex subunit MIC60 | chr2 | Not Cancer Driver | No | 2 | intact, hippie | 97 | 400 | 50 | 50 | 0 |
| IMPDH1_ENST00000626419 | IMPDH1 | P20839 | Inosine-5'-monophosphate dehydrogenase 1 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 75 | 13 | 1 | 1 | 7 |
| INPP5B_ENST00000373026 | INPP5B | P32019 | Type II inositol 1,4,5-trisphosphate 5-phosphatase | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 108 | 114 | 11 | 11 | 0 |
| INS | INS | P01308 | Insulin | chr11 | Not Cancer Driver | No | 1 | hippie | 15 | 5 | 1 | 1 | 22 |
| ISLR | ISLR | O14498 | Immunoglobulin superfamily containing leucine-rich repeat protein | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 83 | 87 | 13 | 13 | 0 |
| KIF14 | KIF14 | Q15058 | Kinesin-like protein KIF14 | chr1 | Not Cancer Driver | No | 1 | hippie | 222 | 774 | 102 | 102 | 2 |
| LACTB | LACTB | P83111 | Serine beta-lactamase-like protein LACTB, mitochondrial | chr15 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 44 | 121 | 3 | 3 | 0 |
| LATS1 | LATS1 | O95835 | Serine/threonine-protein kinase LATS1 | chr6 | Census, Compendium | Yes | 1 | hippie, biogrid | 161 | 788 | 100 | 100 | 0 |
| LATS2 | LATS2 | Q9NRM7 | Serine/threonine-protein kinase LATS2 | chr13 | Census, Compendium | Yes | 1 | intact, hippie, biogrid | 178 | 687 | 116 | 116 | 0 |
| LMBR1L | LMBR1L | Q6UX01 | Protein LMBR1L | chr12 | Not Cancer Driver | No | 1 | hippie | 57 | 4 | 0 | 0 | 0 |
| LRRC25_ENST00000595840 | LRRC25 | Q8N386 | Leucine-rich repeat-containing protein 25 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 40 | 89 | 14 | 14 | 0 |
| LXN | LXN | Q9BS40 | Latexin | chr3 | Not Cancer Driver | No | 1 | hippie | 21 | 91 | 9 | 9 | 0 |
| MAD2L2 | MAD2L2 | Q9UI95 | Mitotic spindle assembly checkpoint protein MAD2B | chr1 | Not Cancer Driver | No | 1 | hippie | 22 | 0 | 0 | 0 | 1 |
| MCOLN3 | MCOLN3 | Q8TDD5 | Mucolipin-3 | chr1 | Not Cancer Driver | No | 3 | hippie, biogrid | 102 | 9 | 2 | 2 | 0 |
| MGST3 | MGST3 | O14880 | Microsomal glutathione S-transferase 3 | chr1 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 17 | 0 | 0 | 0 | 0 |
| MINOS1 | MICOS10 | Q5TGZ0 | MICOS complex subunit MIC10 | chr1 | Not Cancer Driver | No | 1 | hippie | 5 | 0 | 0 | 0 | 0 |
| MKS1 | MKS1 | Q9NXB0 | Meckel syndrome type 1 protein | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 82 | 152 | 23 | 23 | 2 |
| MME_ENST00000492661 | MME | P08473 | Neprilysin | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 189 | 40 | 17 | 17 | 4 |
| MRPS12_ENST00000402029 | MRPS12 | O15235 | 28S ribosomal protein S12, mitochondrial | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 59 | 11 | 11 | 0 |
| MTCH1 | MTCH1 | Q9NZJ7 | Mitochondrial carrier homolog 1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 102 | 2 | 2 | 0 |
| MTCH2 | MTCH2 | Q9Y6C9 | Mitochondrial carrier homolog 2 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 45 | 11 | 0 | 0 | 0 |
| MTMR7 | MTMR7 | Q9Y216 | Myotubularin-related protein 7 | chr8 | Not Cancer Driver | No | 1 | hippie | 98 | 160 | 26 | 26 | 0 |
| MTX2 | MTX2 | O75431 | Metaxin-2 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 33 | 0 | 0 | 0 | 0 |
| NASP | NASP | P49321 | Nuclear autoantigenic sperm protein | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 95 | 615 | 81 | 81 | 0 |
| NDUFS7 | NDUFS7 | O75251 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 36 | 30 | 3 | 3 | 1 |
| NDUFS8 | NDUFS8 | O00217 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 37 | 2 | 2 | 3 |
| NIPAL1 | NIPAL1 | Q6NVV3 | Magnesium transporter NIPA3 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 2 | 0 | 0 | 0 |
| NR2C2_ENST00000393102 | NR2C2 | P49116 | Nuclear receptor subfamily 2 group C member 2 | chr3 | Not Cancer Driver | No | 1 | hippie | 62 | 186 | 24 | 24 | 0 |
| NTRK1 | NTRK1 | P04629 | High affinity nerve growth factor receptor | chr1 | Census, Compendium | Yes | 1 | hippie | 168 | 57 | 8 | 8 | 25 |
| NUCB1 | NUCB1 | Q02818 | Nucleobindin-1 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 56 | 352 | 43 | 43 | 0 |
| OCIAD1 | OCIAD1 | Q9NX40 | OCIA domain-containing protein 1 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 169 | 25 | 25 | 0 |
| OMA1 | OMA1 | Q96E52 | Metalloendopeptidase OMA1, mitochondrial | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 52 | 34 | 4 | 4 | 0 |
| OPA1_ENST00000392438 | OPA1 | O60313 | Dynamin-like 120 kDa protein, mitochondrial | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 114 | 131 | 17 | 17 | 60 |
| P2RY2_ENST00000393596 | P2RY2 | P41231 | P2Y purinoceptor 2 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 60 | 13 | 13 | 0 |
| PCDHB3 | PCDHB3 | Q9Y5E6 | Protocadherin beta-3 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 258 | 119 | 30 | 30 | 0 |
| PDE6D | PDE6D | O43924 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 1 | 0 | 0 | 0 |
| PEX19 | PEX19 | P40855 | Peroxisomal biogenesis factor 19 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 266 | 38 | 38 | 0 |
| PFDN6_ENST00000374610 | PFDN6 | O15212 | Prefoldin subunit 6 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 14 | 57 | 8 | 8 | 0 |
| PHB2 | PHB2 | Q99623 | Prohibitin-2 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 26 | 4 | 4 | 0 |
| PIGH | PIGH | Q14442 | Phosphatidylinositol N-acetylglucosaminyltransferase subunit H | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 12 | 1 | 0 | 0 | 1 |
| PIH1D1 | PIH1D1 | Q9NWS0 | PIH1 domain-containing protein 1 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 30 | 157 | 13 | 13 | 0 |
| PITPNB_ENST00000335272 | PITPNB | P48739 | Phosphatidylinositol transfer protein beta isoform | chr22 | Not Cancer Driver | No | 1 | intact, hippie | 26 | 69 | 2 | 2 | 0 |
| PLD6 | PLD6 | Q8N2A8 | Mitochondrial cardiolipin hydrolase | chr17 | Not Cancer Driver | No | 1 | biogrid | 27 | 24 | 6 | 6 | 0 |
| PLEKHA4 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 136 | 687 | 128 | 128 | 0 |
| PLGRKT | PLGRKT | Q9HBL7 | Plasminogen receptor (KT) | chr9 | Not Cancer Driver | No | 1 | intact, hippie | 17 | 0 | 0 | 0 | 0 |
| PM20D2 | PM20D2 | Q8IYS1 | Xaa-Arg dipeptidase | chr6 | Not Cancer Driver | No | 1 | hippie | 39 | 79 | 7 | 7 | 0 |
| PML | PML | P29590 | Protein PML | chr15 | Census, Compendium | Yes | 1 | hippie, biogrid | 112 | 312 | 34 | 34 | 0 |
| PNP | PNP | P00491 | Purine nucleoside phosphorylase | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 38 | 29 | 2 | 2 | 5 |
| PPP5C | PPP5C | P53041 | Serine/threonine-protein phosphatase 5 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 70 | 73 | 12 | 12 | 0 |
| PPP6R1_ENST00000587283 | PPP6R1 | Q9UPN7 | Serine/threonine-protein phosphatase 6 regulatory subunit 1 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 82 | 471 | 47 | 47 | 0 |
| PPP6R3_ENST00000393800 | PPP6R3 | Q5H9R7 | Serine/threonine-protein phosphatase 6 regulatory subunit 3 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 108 | 389 | 52 | 52 | 0 |
| PPTC7 | PPTC7 | Q8NI37 | Protein phosphatase PTC7 homolog | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 32 | 36 | 2 | 2 | 0 |
| PRELID3B | PRELID3B | Q9Y3B1 | PRELI domain containing protein 3B | chr20 | Not Cancer Driver | No | 1 | hippie | 20 | 72 | 9 | 9 | 0 |
| PRICKLE3 | PRICKLE3 | O43900 | Prickle planar cell polarity protein 3 | chrX | Not Cancer Driver | No | 1 | hippie | 76 | 276 | 33 | 33 | 1 |
| PSMD8 | PSMD8 | P48556 | 26S proteasome non-ATPase regulatory subunit 8 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 78 | 2 | 2 | 0 |
| PTGES3_ENST00000262033 | PTGES3 | Q15185 | Prostaglandin E synthase 3 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 11 | 52 | 3 | 3 | 0 |
| PTP4A3_ENST00000521578 | PTP4A3 | O75365 | Protein tyrosine phosphatase type IVA 3 | chr8 | Not Cancer Driver | No | 1 | intact, hippie | 30 | 3 | 0 | 0 | 0 |
| RALY | RALY | Q9UKM9 | RNA-binding protein Raly | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 187 | 32 | 32 | 0 |
| RBM26_ENST00000438737 | RBM26 | Q5T8P6 | RNA-binding protein 26 | chr13 | Not Cancer Driver | No | 1 | hippie | 117 | 834 | 100 | 100 | 0 |
| RBM4_ENST00000310092 | RBM4 | Q9BWF3 | RNA-binding protein 4 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 40 | 129 | 12 | 12 | 0 |
| RCN1 | RCN1 | Q15293 | Reticulocalbin-1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 35 | 158 | 19 | 19 | 0 |
| RCN2_ENST00000394885 | RCN2 | Q14257 | Reticulocalbin-2 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 35 | 125 | 11 | 11 | 0 |
| RHOT2 | RHOT2 | Q8IXI1 | Mitochondrial Rho GTPase 2 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 52 | 79 | 5 | 5 | 0 |
| RIC3 | RIC3 | Q7Z5B4 | Protein RIC-3 | chr11 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 72 | 281 | 62 | 62 | 0 |
| RNF214_ENST00000531452 | RNF214 | Q8ND24 | RING finger protein 214 | chr11 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 84 | 528 | 66 | 66 | 0 |
| RPAP3 | RPAP3 | Q9H6T3 | RNA polymerase II-associated protein 3 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 59 | 334 | 37 | 37 | 0 |
| RPL18A | RPL18A | Q02543 | 60S ribosomal protein L18a | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 25 | 4 | 4 | 0 |
| RPS6KA1_ENST00000374168 | RPS6KA1 | Q15418 | Ribosomal protein S6 kinase alpha-1 | chr1 | Not Cancer Driver | No | 1 | hippie | 94 | 178 | 32 | 32 | 0 |
| RPS6KA5 | RPS6KA5 | O75582 | Ribosomal protein S6 kinase alpha-5 | chr14 | Not Cancer Driver | No | 1 | hippie | 97 | 187 | 18 | 18 | 0 |
| RTRAF | RTRAF | Q9Y224 | RNA transcription, translation and transport factor protein | chr14 | Not Cancer Driver | No | 1 | intact, hippie | 24 | 35 | 1 | 1 | 0 |
| SAMM50 | SAMM50 | Q9Y512 | Sorting and assembly machinery component 50 homolog | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 34 | 1 | 1 | 0 |
| SAYSD1 | SAYSD1 | Q9NPB0 | SAYSvFN domain-containing protein 1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 67 | 4 | 4 | 0 |
| SCCPDH | SCCPDH | Q8NBX0 | Saccharopine dehydrogenase-like oxidoreductase | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 56 | 26 | 1 | 1 | 0 |
| SCO1 | SCO1 | O75880 | Protein SCO1 homolog, mitochondrial | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 35 | 79 | 7 | 7 | 1 |
| SFXN1 | SFXN1 | Q9H9B4 | Sideroflexin-1 | chr5 | Not Cancer Driver | No | 1 | intact, hippie | 31 | 29 | 1 | 1 | 0 |
| SGCA | SGCA | Q16586 | Alpha-sarcoglycan | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 82 | 9 | 9 | 29 |
| SHROOM3 | SHROOM3 | Q8TF72 | Protein Shroom3 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 253 | 1756 | 220 | 220 | 0 |
| SLC25A46 | SLC25A46 | Q96AG3 | Mitochondrial outer membrane protein SLC25A46 | chr5 | Not Cancer Driver | No | 2 | hippie, biogrid | 37 | 96 | 2 | 2 | 4 |
| SLC25A51_ENST00000242275 | SLC25A51 | Q9H1U9 | Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 21 | 0 | 0 | 0 |
| SLFN11_ENST00000308377 | SLFN11 | Q7Z7L1 | Schlafen family member 11 | chr17 | Not Cancer Driver | No | 1 | hippie | 177 | 34 | 8 | 8 | 0 |
| SOCS6_ENST00000582322 | SOCS6 | O14544 | Suppressor of cytokine signaling 6 | chr18 | Not Cancer Driver | No | 1 | hippie | 81 | 299 | 48 | 48 | 0 |
| SPART_ENST00000355182 | SPART | Q8N0X7 | Spartin | chr13 | Not Cancer Driver | No | 1 | hippie | 112 | 396 | 68 | 68 | 1 |
| SPRTN | SPRTN | Q9H040 | DNA-dependent metalloprotease SPRTN | chr1 | Not Cancer Driver | No | 1 | hippie | 73 | 252 | 38 | 38 | 1 |
| STUB1 | STUB1 | Q9UNE7 | E3 ubiquitin-protein ligase CHIP | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 35 | 112 | 14 | 14 | 12 |
| STXBP1_ENST00000373299 | STXBP1 | P61764 | Syntaxin-binding protein 1 | chr9 | Not Cancer Driver | No | 1 | intact, hippie | 97 | 111 | 23 | 23 | 18 |
| SUGT1 | SUGT1 | Q9Y2Z0 | Protein SGT1 homolog | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 119 | 5 | 5 | 0 |
| SUOX_ENST00000356124 | SUOX | P51687 | Sulfite oxidase, mitochondrial | chr12 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 68 | 184 | 32 | 32 | 11 |
| SURF1 | SURF1 | Q15526 | Surfeit locus protein 1 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 17 | 82 | 6 | 6 | 11 |
| SYNE4 | SYNE4 | Q8N205 | Nesprin-4 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 236 | 31 | 31 | 0 |
| SYNGR1 | SYNGR1 | O43759 | Synaptogyrin-1 | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 48 | 5 | 5 | 0 |
| SYP | SYP | P08247 | Synaptophysin | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 36 | 93 | 8 | 8 | 1 |
| TAX1BP1 | TAX1BP1 | Q86VP1 | Tax1-binding protein 1 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 78 | 429 | 50 | 50 | 0 |
| TBX3 | TBX3 | O15119 | T-box transcription factor TBX3 | chr12 | Census, Compendium | Yes | 1 | intact, hippie | 123 | 352 | 57 | 57 | 2 |
| TCTN3 | TCTN3 | Q6NUS6 | Tectonic-3 | chr10 | Not Cancer Driver | No | 1 | intact, hippie | 45 | 71 | 8 | 8 | 1 |
| TIMM29 | TIMM29 | Q9BSF4 | Mitochondrial import inner membrane translocase subunit Tim29 | chr19 | Not Cancer Driver | No | 1 | hippie | 9 | 4 | 0 | 0 | 0 |
| TIMM50_ENST00000607714 | TIMM50 | Q3ZCQ8 | Mitochondrial import inner membrane translocase subunit TIM50 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 39 | 75 | 7 | 7 | 0 |
| TMEM171 | TMEM171 | Q8WVE6 | Transmembrane protein 171 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 54 | 150 | 18 | 18 | 0 |
| TMEM184A | TMEM184A | Q6ZMB5 | Transmembrane protein 184A | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 59 | 76 | 17 | 17 | 0 |
| TMEM231 | TMEM231 | Q9H6L2 | Transmembrane protein 231 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 16 | 1 | 1 | 2 |
| TMEM63A | TMEM63A | O94886 | CSC1-like protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 87 | 36 | 1 | 1 | 3 |
| TMEM72 | TMEM72 | A0PK05 | Transmembrane protein 72 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 98 | 22 | 22 | 0 |
| TMPO | TMPO | P42166 | Lamina-associated polypeptide 2, isoform alpha | chr12 | Not Cancer Driver | No | 1 | hippie | 78 | 412 | 52 | 52 | 0 |
| TMPRSS11B | TMPRSS11B | Q86T26 | Transmembrane protease serine 11B | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 95 | 5 | 0 | 0 | 0 |
| TOMM22 | TOMM22 | Q9NS69 | Mitochondrial import receptor subunit TOM22 homolog | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 83 | 9 | 9 | 0 |
| TPT1_ENST00000530705 | TPT1 | P13693 | Translationally-controlled tumor protein | chr13 | Not Cancer Driver | No | 1 | hippie | 17 | 43 | 6 | 6 | 0 |
| TRABD_ENST00000395827 | TRABD | Q9H4I3 | TraB domain-containing protein | chr22 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 38 | 66 | 6 | 6 | 0 |
| TRAP1 | TRAP1 | Q12931 | Heat shock protein 75 kDa, mitochondrial | chr16 | Not Cancer Driver | No | 1 | intact, hippie | 74 | 110 | 11 | 11 | 0 |
| TRIM25 | TRIM25 | Q14258 | E3 ubiquitin/ISG15 ligase TRIM25 | chr17 | Not Cancer Driver | No | 1 | hippie | 59 | 225 | 20 | 20 | 0 |
| TUBB6 | TUBB6 | Q9BUF5 | Tubulin beta-6 chain | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 69 | 51 | 5 | 5 | 1 |
| TUSC2 | TUSC2 | O75896 | Tumor suppressor candidate 2 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 10 | 31 | 3 | 3 | 0 |
| UBXN6 | UBXN6 | Q9BZV1 | UBX domain-containing protein 6 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 64 | 132 | 26 | 26 | 0 |
| UFL1 | UFL1 | O94874 | E3 UFM1-protein ligase 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 109 | 141 | 24 | 24 | 0 |
| UNC45A | UNC45A | Q9H3U1 | Protein unc-45 homolog A | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 78 | 128 | 4 | 4 | 0 |
| UQCRC1 | UQCRC1 | P31930 | Cytochrome b-c1 complex subunit 1, mitochondrial | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 57 | 55 | 6 | 6 | 2 |
| VPS52 | VPS52 | Q8N1B4 | Vacuolar protein sorting-associated protein 52 homolog | chr6 | Not Cancer Driver | No | 1 | hippie | 89 | 36 | 5 | 5 | 0 |
| VSIG4 | VSIG4 | Q9Y279 | V-set and immunoglobulin domain-containing protein 4 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 73 | 70 | 13 | 13 | 0 |
| WDR5 | WDR5 | P61964 | WD repeat-containing protein 5 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 30 | 35 | 3 | 3 | 0 |
| WDR73 | WDR73 | Q6P4I2 | WD repeat-containing protein 73 | chr15 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 29 | 86 | 7 | 7 | 0 |
| XPO1_ENST00000406957 | XPO1 | O14980 | Exportin-1 | chr2 | Census, Compendium | Yes | 1 | hippie | 140 | 33 | 9 | 9 | 0 |
| YME1L1 | YME1L1 | Q96TA2 | ATP-dependent zinc metalloprotease YME1L1 | chr10 | Not Cancer Driver | No | 1 | intact, hippie | 112 | 136 | 14 | 14 | 1 |
| YTHDF1 | YTHDF1 | Q9BYJ9 | YTH domain-containing family protein 1 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 87 | 369 | 46 | 46 | 0 |
| ZNHIT2 | ZNHIT2 | Q9UHR6 | Zinc finger HIT domain-containing protein 2 | chr11 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 29 | 157 | 15 | 15 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|