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DNAJB4 ,DNAJB4 ,Q9UDY4
  • Uniprot Accession= Q9UDY4
  • Ensembl Transcript= ENST00000370763.5
  • Uniprot Name= DNAJB4
  • Name= DnaJ homolog subfamily B member 4
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 34
  • Number of Interaction partner in biogrid: 73
  • Number of Interaction partner in hippie: 125
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABHD15 ABHD15 Q6UXT9 Protein ABHD15 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 50 41 3 3 0
AHSA1 AHSA1 O95433 Activator of 90 kDa heat shock protein ATPase homolog 1 chr14 Not Cancer Driver No 2 hippie, biogrid 46 146 17 17 0
AKAP10 AKAP10 O43572 A-kinase anchor protein 10, mitochondrial chr17 Not Cancer Driver No 1 hippie 51 304 16 16 0
ANGPTL4 ANGPTL4 Q9BY76 Angiopoietin-related protein 4 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 47 180 22 22 0
ANK2 ANK2 Q01484 Ankyrin-2 chr4 Not Cancer Driver No 1 hippie, biogrid 770 2844 566 566 4
APOBEC3D APOBEC3D Q96AK3 DNA dC->dU-editing enzyme APOBEC-3D chr22 Not Cancer Driver No 2 intact, hippie, biogrid 43 3 0 0 0
ARGLU1 ARGLU1 Q9NWB6 Arginine and glutamate-rich protein 1 chr13 Not Cancer Driver No 1 hippie, biogrid 37 246 33 33 0
ASB4 ASB4 Q9Y574 Ankyrin repeat and SOCS box protein 4 chr7 Not Cancer Driver No 1 hippie 82 19 1 1 0
ATP5PO ATP5PO P48047 ATP synthase subunit O, mitochondrial chr21 Not Cancer Driver No 1 hippie 19 9 2 2 0
ATXN1 ATXN1 P54253 Ataxin-1 chr6 Not Cancer Driver No 1 intact, hippie 193 604 168 168 0
BAG1 BAG1 Q99933 BAG family molecular chaperone regulator 1 chr9 Not Cancer Driver No 1 intact, hippie 29 195 9 9 0
BAG2 BAG2 O95816 BAG family molecular chaperone regulator 2 chr6 Not Cancer Driver No 2 hippie, biogrid 17 112 9 9 0
BAG3 BAG3 O95817 BAG family molecular chaperone regulator 3 chr10 Not Cancer Driver No 1 hippie 57 571 57 57 7
BAG5_ENST00000299204 BAG5 Q9UL15 BAG family molecular chaperone regulator 5 chr14 Not Cancer Driver No 2 hippie, biogrid 37 63 7 7 0
BCAR1_ENST00000162330 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 Not Cancer Driver No 1 hippie 108 677 75 75 0
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 193 1182 172 172 0
C3orf38 C3orf38 Q5JPI3 Uncharacterized protein C3orf38 chr3 Not Cancer Driver No 3 intact, hippie, biogrid 40 50 6 6 0
CARD8_ENST00000519940 CARD8 Q9Y2G2 Caspase recruitment domain-containing protein 8 chr19 Not Cancer Driver No 1 hippie, biogrid 53 126 7 7 1
CBX5 CBX5 P45973 Chromobox protein homolog 5 chr12 Not Cancer Driver No 1 hippie, biogrid 21 116 12 12 0
CCDC138 CCDC138 Q96M89 Coiled-coil domain-containing protein 138 chr2 Not Cancer Driver No 1 hippie, biogrid 76 202 25 25 0
CCDC61 CCDC61 Q9Y6R9 Centrosomal protein CCDC61 chr19 Not Cancer Driver No 1 hippie, biogrid 44 348 32 32 0
CRMP1_ENST00000397890 CRMP1 Q14194 Dihydropyrimidinase-related protein 1 chr4 Not Cancer Driver No 1 hippie 122 96 15 15 0
DET1_ENST00000268148 DET1 Q7L5Y6 DET1 homolog chr15 Not Cancer Driver No 1 hippie, biogrid 97 42 12 12 0
DNAJB1 DNAJB1 P25685 DnaJ homolog subfamily B member 1 chr19 Census, Compendium Yes 4 intact, hippie, biogrid 35 196 26 26 0
DNAJB5_ENST00000312316 DNAJB5 O75953 DnaJ homolog subfamily B member 5 chr9 Not Cancer Driver No 4 hippie, biogrid 49 147 18 18 0
DNAJB6 DNAJB6 O75190 DnaJ homolog subfamily B member 6 chr7 Not Cancer Driver No 1 hippie, biogrid 33 198 17 17 3
DNAJC7 DNAJC7 Q99615 DnaJ homolog subfamily C member 7 chr17 Not Cancer Driver No 1 intact, hippie 41 102 9 9 0
ECPAS_ENST00000338205 ECPAS Q5VYK3 Proteasome adapter and scaffold protein ECM29 chr9 Not Cancer Driver No 1 hippie 176 240 22 22 0
EFTUD2 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 132 179 30 30 3
EIF4H EIF4H Q15056 Eukaryotic translation initiation factor 4H chr7 Not Cancer Driver No 1 hippie, biogrid 30 175 17 17 0
ERCC8 ERCC8 Q13216 DNA excision repair protein ERCC-8 chr5 Not Cancer Driver No 1 hippie 25 53 8 8 7
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
ETF1 ETF1 P62495 Eukaryotic peptide chain release factor subunit 1 chr5 Not Cancer Driver No 1 hippie, biogrid 60 28 11 11 0
FBXW11 FBXW11 Q9UKB1 F-box/WD repeat-containing protein 11 chr5 Not Cancer Driver No 1 hippie 75 20 3 3 7
GLB1 GLB1 P16278 Beta-galactosidase chr3 Not Cancer Driver No 2 intact, hippie, biogrid 72 54 6 6 99
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 hippie, biogrid 28 10 1 1 0
GRPEL1 GRPEL1 Q9HAV7 GrpE protein homolog 1, mitochondrial chr4 Not Cancer Driver No 1 hippie, biogrid 22 88 7 7 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 Not Cancer Driver No 1 hippie 24 200 13 13 0
HSPA1L HSPA1L P34931 Heat shock 70 kDa protein 1-like chr6 Not Cancer Driver No 1 hippie, biogrid 119 141 28 28 0
HSPA2_ENST00000247207 HSPA2 P54652 Heat shock-related 70 kDa protein 2 chr14 Not Cancer Driver No 1 hippie, biogrid 93 286 38 38 0
HSPA4 HSPA4 P34932 Heat shock 70 kDa protein 4 chr5 Not Cancer Driver No 2 hippie, biogrid 80 351 24 24 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 Not Cancer Driver No 1 intact, hippie 73 282 35 35 0
HSPA6 HSPA6 P17066 Heat shock 70 kDa protein 6 chr1 Not Cancer Driver No 1 intact, hippie 112 235 27 27 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 3 hippie, biogrid 149 251 52 52 0
HSPA9 HSPA9 P38646 Stress-70 protein, mitochondrial chr5 Not Cancer Driver No 1 hippie, biogrid 67 283 26 26 2
HSPH1_ENST00000320027 HSPH1 Q92598 Heat shock protein 105 kDa chr13 Not Cancer Driver No 3 hippie, biogrid 103 323 42 42 0
HTT HTT P42858 Huntingtin chr4 Not Cancer Driver No 1 intact, hippie 336 666 69 69 2
HYOU1 HYOU1 Q9Y4L1 Hypoxia up-regulated protein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 132 373 47 47 0
INF2 INF2 Q27J81 Inverted formin-2 chr14 Not Cancer Driver No 1 hippie, biogrid 120 635 49 49 30
ISG15 ISG15 P05161 Ubiquitin-like protein ISG15 chr1 Not Cancer Driver No 1 hippie 12 24 2 2 0
JUN JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 35 281 25 25 0
KCNC4 KCNC4 Q03721 Potassium voltage-gated channel subfamily C member 4 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 105 244 38 38 0
KCNE3 KCNE3 Q9Y6H6 Potassium voltage-gated channel subfamily E member 3 chr11 Not Cancer Driver No 1 hippie, biogrid 28 24 2 2 0
KHDC1 KHDC1 Q4VXA5 KH homology domain-containing protein 1 chr6 Not Cancer Driver No 1 hippie, biogrid 38 23 2 2 0
KLHL26 KLHL26 Q53HC5 Kelch-like protein 26 chr19 Not Cancer Driver No 1 hippie, biogrid 75 56 5 5 0
KLHL34 KLHL34 Q8N239 Kelch-like protein 34 chrX Not Cancer Driver No 1 hippie, biogrid 103 77 12 12 0
L3MBTL2 L3MBTL2 Q969R5 Lethal(3)malignant brain tumor-like protein 2 chr22 Not Cancer Driver No 1 hippie, biogrid 95 210 38 38 0
LCMT2 LCMT2 O60294 tRNA wybutosine-synthesizing protein 4 chr15 Not Cancer Driver No 1 hippie, biogrid 101 33 2 2 0
LOXL4 LOXL4 Q96JB6 Lysyl oxidase homolog 4 chr10 Not Cancer Driver No 1 hippie, biogrid 95 122 11 11 0
LTV1 LTV1 Q96GA3 Protein LTV1 homolog chr6 Not Cancer Driver No 1 hippie, biogrid 45 388 30 30 0
MANSC1 MANSC1 Q9H8J5 MANSC domain-containing protein 1 chr12 Not Cancer Driver No 2 intact, hippie, biogrid 53 206 21 21 0
MAP3K3_ENST00000361733 MAP3K3 Q99759 Mitogen-activated protein kinase kinase kinase 3 chr17 Not Cancer Driver No 1 intact, hippie 74 355 44 44 0
MAS1 MAS1 P04201 Proto-oncogene Mas chr6 Not Cancer Driver No 1 hippie, biogrid 47 5 2 2 0
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 Census, Compendium Yes 1 intact, hippie 56 297 37 37 0
METTL3 METTL3 Q86U44 N6-adenosine-methyltransferase catalytic subunit chr14 Not Cancer Driver No 1 hippie 74 274 29 29 0
MLF1_ENST00000355893 MLF1 P58340 Myeloid leukemia factor 1 chr3 Census Yes 1 hippie, biogrid 40 243 37 37 0
MLF2_ENST00000542154 MLF2 Q15773 Myeloid leukemia factor 2 chr12 Not Cancer Driver No 2 hippie, biogrid 37 187 32 32 0
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 110 101 8 8 0
MRGPRX4 MRGPRX4 Q96LA9 Mas-related G-protein coupled receptor member X4 chr11 Not Cancer Driver No 1 hippie, biogrid 82 10 0 0 0
MS4A15 MS4A15 Q8N5U1 Membrane-spanning 4-domains subfamily A member 15 chr11 Not Cancer Driver No 1 hippie, biogrid 41 27 6 6 0
NBR1 NBR1 Q14596 Next to BRCA1 gene 1 protein chr17 Not Cancer Driver No 1 hippie, biogrid 101 560 51 51 0
NLRP8 NLRP8 Q86W28 NACHT, LRR and PYD domains-containing protein 8 chr19 Not Cancer Driver No 1 hippie, biogrid 329 50 16 16 0
NPAS1_ENST00000449844 NPAS1 Q99742 Neuronal PAS domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie, biogrid 53 309 23 23 0
NPM1 NPM1 P06748 Nucleophosmin chr5 Census, Compendium Yes 1 hippie 29 249 22 22 0
NRBP1_ENST00000379852 NRBP1 Q9UHY1 Nuclear receptor-binding protein chr2 Not Cancer Driver No 1 hippie, biogrid 64 189 29 29 0
NUDC NUDC Q9Y266 Nuclear migration protein nudC chr1 Not Cancer Driver No 2 intact, hippie 36 235 29 29 0
OPRM1_ENST00000330432 OPRM1 P35372 Mu-type opioid receptor chr6 Not Cancer Driver No 1 hippie 107 58 27 27 0
OR6T1 OR6T1 Q8NGN1 Olfactory receptor 6T1 chr11 Not Cancer Driver No 1 hippie, biogrid 125 0 0 0 0
P2RX6 P2RX6 O15547 P2X purinoceptor 6 chr22 Not Cancer Driver No 3 intact, hippie, biogrid 33 43 1 1 0
PABPN1 PABPN1 Q86U42 Polyadenylate-binding protein 2 chr14 Not Cancer Driver No 1 intact, hippie 27 241 18 18 0
PELI3 PELI3 Q8N2H9 E3 ubiquitin-protein ligase pellino homolog 3 chr11 Not Cancer Driver No 1 hippie, biogrid 48 216 25 25 0
PGRMC1 PGRMC1 O00264 Membrane-associated progesterone receptor component 1 chrX Not Cancer Driver No 1 hippie, biogrid 30 74 16 16 0
PLD2 PLD2 O14939 Phospholipase D2 chr17 Not Cancer Driver No 1 biogrid 107 97 8 8 0
PLD5 PLD5 Q8N7P1 Inactive phospholipase D5 chr1 Not Cancer Driver No 1 biogrid 152 62 18 18 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
POLR1D POLR1D P0DPB6 DNA-directed RNA polymerases I and III subunit RPAC2 chr13 Not Cancer Driver No 1 intact, hippie 17 87 13 13 7
PRPF8 PRPF8 Q6P2Q9 Pre-mRNA-processing-splicing factor 8 chr17 Not Cancer Driver No 1 hippie 255 225 26 26 8
PSPC1_ENST00000619300 PSPC1 Q8WXF1 Paraspeckle component 1 chr13 Not Cancer Driver No 1 hippie, biogrid 97 367 81 81 0
PYCR3_ENST00000495276 PYCR3 Q53H96 Pyrroline-5-carboxylate reductase 3 chr8 Not Cancer Driver No 1 hippie 21 11 0 0 0
RAD21 RAD21 O60216 Double-strand-break repair protein rad21 homolog chr8 Census, Compendium Yes 1 hippie 115 421 74 74 3
RANBP3 RANBP3 Q9H6Z4 Ran-binding protein 3 chr19 Not Cancer Driver No 1 hippie 71 468 54 54 0
RCN2_ENST00000394885 RCN2 Q14257 Reticulocalbin-2 chr15 Not Cancer Driver No 1 hippie, biogrid 35 125 11 11 0
RPS25 RPS25 P62851 40S ribosomal protein S25 chr11 Not Cancer Driver No 1 hippie, biogrid 16 60 8 8 0
RUVBL2 RUVBL2 Q9Y230 RuvB-like 2 chr19 Not Cancer Driver No 1 intact, hippie 62 100 13 13 0
SHARPIN SHARPIN Q9H0F6 Sharpin chr8 Not Cancer Driver No 1 intact, hippie 34 237 16 16 0
SHMT2 SHMT2 P34897 Serine hydroxymethyltransferase, mitochondrial chr12 Not Cancer Driver No 1 hippie 57 58 5 5 1
SIM2 SIM2 Q14190 Single-minded homolog 2 chr21 Not Cancer Driver No 1 hippie, biogrid 62 262 12 12 0
SLC16A11 SLC16A11 Q8NCK7 Monocarboxylate transporter 11 chr17 Not Cancer Driver No 1 hippie 33 72 5 5 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 Census, Compendium Yes 1 intact, hippie 97 111 19 19 5
ST13 ST13 P50502 Hsc70-interacting protein chr22 Not Cancer Driver No 1 hippie, biogrid 38 297 29 29 0
STIP1_ENST00000305218 STIP1 P31948 Stress-induced-phosphoprotein 1 chr11 Not Cancer Driver No 2 hippie, biogrid 74 270 39 39 0
STYK1 STYK1 Q6J9G0 Tyrosine-protein kinase STYK1 chr12 Not Cancer Driver No 1 intact 83 35 10 10 0
SYNM SYNM O15061 Synemin chr15 Not Cancer Driver No 4 hippie, biogrid 156 1244 131 131 0
TANK TANK Q92844 TRAF family member-associated NF-kappa-B activator chr2 Not Cancer Driver No 1 intact, hippie 42 302 26 26 0
TAX1BP1 TAX1BP1 Q86VP1 Tax1-binding protein 1 chr7 Not Cancer Driver No 1 hippie 78 429 50 50 0
TBC1D22A TBC1D22A Q8WUA7 TBC1 domain family member 22A chr22 Not Cancer Driver No 3 intact, hippie, biogrid 84 219 23 23 0
TBL1X TBL1X O60907 F-box-like/WD repeat-containing protein TBL1X chrX Not Cancer Driver No 1 intact, hippie 85 181 35 35 0
TBL1Y TBL1Y Q9BQ87 F-box-like/WD repeat-containing protein TBL1Y chrY Not Cancer Driver No 2 intact, hippie, biogrid 31 138 8 8 0
TBPL2 TBPL2 Q6SJ96 TATA box-binding protein-like 2 chr14 Not Cancer Driver No 1 hippie 45 190 30 30 0
TGS1 TGS1 Q96RS0 Trimethylguanosine synthase chr8 Not Cancer Driver No 1 hippie 100 483 56 56 0
TIGAR TIGAR Q9NQ88 Fructose-2,6-bisphosphatase TIGAR chr12 Not Cancer Driver No 1 hippie 44 39 9 9 0
TLE2_ENST00000262953 TLE2 Q04725 Transducin-like enhancer protein 2 chr19 Not Cancer Driver No 1 hippie, biogrid 78 283 29 29 0
TMEM231 TMEM231 Q9H6L2 Transmembrane protein 231 chr16 Not Cancer Driver No 1 hippie, biogrid 15 16 1 1 2
TPT1_ENST00000530705 TPT1 P13693 Translationally-controlled tumor protein chr13 Not Cancer Driver No 1 hippie 17 43 6 6 0
TPTE2 TPTE2 Q6XPS3 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 chr13 Not Cancer Driver No 1 hippie, biogrid 210 33 13 13 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TSR1 TSR1 Q2NL82 Pre-rRNA-processing protein TSR1 homolog chr17 Not Cancer Driver No 1 hippie, biogrid 74 332 32 32 0
TTLL1 TTLL1 O95922 Polyglutamylase complex subunit TTLL1 chr22 Not Cancer Driver No 3 hippie, biogrid 69 48 9 9 0
TTLL12 TTLL12 Q14166 Tubulin--tyrosine ligase-like protein 12 chr22 Not Cancer Driver No 4 intact, hippie, biogrid 69 100 6 6 0
TUBA1A TUBA1A Q71U36 Tubulin alpha-1A chain chr12 Not Cancer Driver No 1 intact, hippie 59 52 11 11 8
TUBB3 TUBB3 Q13509 Tubulin beta-3 chain chr16 Not Cancer Driver No 1 intact, hippie 67 53 10 10 12
WDR41 WDR41 Q9HAD4 WD repeat-containing protein 41 chr5 Not Cancer Driver No 1 hippie, biogrid 48 23 2 2 0
WDR72 WDR72 Q3MJ13 WD repeat-containing protein 72 chr15 Not Cancer Driver No 1 hippie, biogrid 217 107 21 21 0
WIPI2 WIPI2 Q9Y4P8 WD repeat domain phosphoinositide-interacting protein 2 chr7 Not Cancer Driver No 1 hippie 64 68 5 5 1
WRAP73 WRAP73 Q9P2S5 WD repeat-containing protein WRAP73 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 50 5 0 0 0
YWHAZ_ENST00000395956 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 1 intact, hippie 30 81 10 10 0
ZBTB18_ENST00000622512 ZBTB18 Q99592 Zinc finger and BTB domain-containing protein 18 chr1 Not Cancer Driver No 1 intact 78 236 25 25 0
ZBTB38_ENST00000441582 ZBTB38 Q8NAP3 Zinc finger and BTB domain-containing protein 38 chr3 Not Cancer Driver No 1 hippie 137 648 73 73 0