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DIRAS3_ENST00000646789 ,DIRAS3 ,O95661
  • Uniprot Accession= O95661
  • Ensembl Transcript= ENST00000646789.1
  • Uniprot Name= DIRAS3
  • Name= GTP-binding protein Di-Ras3
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 14
  • Number of Interaction partner in biogrid: 231
  • Number of Interaction partner in hippie: 256
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABCC1 ABCC1 P33527 Multidrug resistance-associated protein 1 chr16 Not Cancer Driver No 1 hippie, biogrid 199 123 22 22 1
ADCY9 ADCY9 O60503 Adenylate cyclase type 9 chr16 Not Cancer Driver No 1 hippie, biogrid 195 271 42 42 0
ADD3 ADD3 Q9UEY8 Gamma-adducin chr10 Not Cancer Driver No 1 hippie, biogrid 95 381 48 48 1
ADGRL2_ENST00000370728 ADGRL2 O95490 Adhesion G protein-coupled receptor L2 chr1 Not Cancer Driver No 1 hippie 373 452 122 122 0
AFG3L2 AFG3L2 Q9Y4W6 AFG3-like protein 2 chr18 Not Cancer Driver No 1 hippie, biogrid 72 162 10 10 22
ALCAM ALCAM Q13740 CD166 antigen chr3 Not Cancer Driver No 1 hippie, biogrid 89 96 19 19 0
ANK3 ANK3 Q12955 Ankyrin-3 chr10 Not Cancer Driver No 1 hippie, biogrid 860 3054 579 579 0
ANKRD26 ANKRD26 Q9UPS8 Ankyrin repeat domain-containing protein 26 chr10 Not Cancer Driver No 1 hippie, biogrid 224 1269 164 164 0
APC APC P25054 Adenomatous polyposis coli protein chr5 Census, Compendium Yes 1 intact, hippie 412 2406 345 345 22
ARF1_ENST00000272102 ARF1 P84077 ADP-ribosylation factor 1 chr1 Not Cancer Driver No 1 hippie, biogrid 30 4 2 2 2
ARHGAP1 ARHGAP1 Q07960 Rho GTPase-activating protein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 39 90 8 8 0
ARHGAP21 ARHGAP21 Q5T5U3 Rho GTPase-activating protein 21 chr10 Not Cancer Driver No 1 hippie, biogrid 242 1612 204 204 0
ATG14 ATG14 Q6ZNE5 Beclin 1-associated autophagy-related key regulator chr14 Not Cancer Driver No 1 hippie 48 209 24 24 0
ATP1A1_ENST00000295598 ATP1A1 P05023 Sodium/potassium-transporting ATPase subunit alpha-1 chr1 Census Yes 1 hippie, biogrid 115 115 16 16 6
ATP2B1_ENST00000261173 ATP2B1 P20020 Plasma membrane calcium-transporting ATPase 1 chr12 Not Cancer Driver No 1 hippie, biogrid 143 293 42 42 0
ATP5F1B ATP5F1B P06576 ATP synthase subunit beta, mitochondrial chr12 Not Cancer Driver No 1 hippie 60 85 8 8 0
ATP7A ATP7A Q04656 Copper-transporting ATPase 1 chrX Not Cancer Driver No 1 hippie, biogrid 228 171 46 46 52
ATPAF1_ENST00000574428 ATPAF1 Q5TC12 ATP synthase mitochondrial F1 complex assembly factor 1 chr1 Not Cancer Driver No 1 hippie, biogrid 33 47 8 8 0
BAG4 BAG4 O95429 BAG family molecular chaperone regulator 4 chr8 Not Cancer Driver No 1 intact, hippie 55 402 49 49 0
BASP1_ENST00000616743 BASP1 P80723 Brain acid soluble protein 1 chr5 Not Cancer Driver No 1 hippie, biogrid 39 227 39 39 0
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 Not Cancer Driver No 1 hippie 45 190 19 19 0
BRMS1_ENST00000359957 BRMS1 Q9HCU9 Breast cancer metastasis-suppressor 1 chr11 Not Cancer Driver No 1 intact, hippie 42 115 18 18 0
BSG BSG P35613 Basigin chr19 Not Cancer Driver No 1 hippie, biogrid 43 123 17 17 0
C2CD4C C2CD4C Q8TF44 C2 calcium-dependent domain-containing protein 4C chr19 Not Cancer Driver No 1 hippie, biogrid 7 314 5 5 0
CACHD1 CACHD1 Q5VU97 VWFA and cache domain-containing protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 174 206 25 25 0
CACYBP CACYBP Q9HB71 Calcyclin-binding protein chr1 Not Cancer Driver No 1 hippie, biogrid 27 92 10 10 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 Not Cancer Driver No 1 hippie, biogrid 30 2 0 0 0
CBARP_ENST00000382477 CBARP Q8N350 Voltage-dependent calcium channel beta subunit-associated regulatory protein chr19 Not Cancer Driver No 1 hippie 41 661 33 33 0
CBX6 CBX6 O95503 Chromobox protein homolog 6 chr22 Not Cancer Driver No 1 hippie, biogrid 57 335 54 54 0
CCDC88A_ENST00000642200 CCDC88A Q3V6T2 Girdin chr2 Not Cancer Driver No 1 hippie, biogrid 226 1481 173 173 0
CDC37 CDC37 Q16543 Hsp90 co-chaperone Cdc37 chr19 Not Cancer Driver No 1 hippie, biogrid 52 214 31 31 0
CDC42BPA_ENST00000334218 CDC42BPA Q5VT25 Serine/threonine-protein kinase MRCK alpha chr1 Not Cancer Driver No 1 hippie, biogrid 215 717 80 80 0
CDC42EP1 CDC42EP1 Q00587 Cdc42 effector protein 1 chr22 Not Cancer Driver No 1 hippie, biogrid 52 371 47 47 0
CDCA3 CDCA3 Q99618 Cell division cycle-associated protein 3 chr12 Not Cancer Driver No 1 hippie, biogrid 26 268 26 26 0
CEMIP2 CEMIP2 Q9UHN6 Cell surface hyaluronidase chr9 Not Cancer Driver No 1 hippie 198 229 26 26 0
CEP89 CEP89 Q96ST8 Centrosomal protein of 89 kDa chr19 Census Yes 1 hippie, biogrid 96 540 72 72 0
CHEK2_ENST00000405598 CHEK2 O96017 Serine/threonine-protein kinase Chk2 chr22 Census, Compendium Yes 1 intact, hippie 335 157 130 130 13
CNNM3 CNNM3 Q8NE01 Metal transporter CNNM3 chr2 Not Cancer Driver No 1 hippie, biogrid 47 101 7 7 0
CNP CNP P09543 2',3'-cyclic-nucleotide 3'-phosphodiesterase chr17 Not Cancer Driver No 1 hippie, biogrid 36 71 2 2 0
CPD CPD O75976 Carboxypeptidase D chr17 Not Cancer Driver No 1 hippie, biogrid 131 476 45 45 0
CPNE8 CPNE8 Q86YQ8 Copine-8 chr12 Not Cancer Driver No 1 hippie, biogrid 102 40 12 12 0
CTNND1 CTNND1 O60716 Catenin delta-1 chr11 Census Yes 1 hippie, biogrid 154 570 83 83 0
CXADR CXADR P78310 Coxsackievirus and adenovirus receptor chr21 Not Cancer Driver No 1 hippie, biogrid 51 98 19 19 0
DCAF10 DCAF10 Q5QP82 DDB1- and CUL4-associated factor 10 chr9 Not Cancer Driver No 3 intact, hippie, biogrid 50 201 11 11 0
DEPDC1B DEPDC1B Q8WUY9 DEP domain-containing protein 1B chr5 Not Cancer Driver No 1 hippie, biogrid 76 52 6 6 0
DLG1_ENST00000419354 DLG1 Q12959 Disks large homolog 1 chr3 Not Cancer Driver No 1 hippie, biogrid 120 460 67 67 0
DLG5 DLG5 Q8TDM6 Disks large homolog 5 chr10 Not Cancer Driver No 1 hippie, biogrid 230 1119 135 135 0
DSC2 DSC2 Q02487 Desmocollin-2 chr18 Not Cancer Driver No 1 hippie, biogrid 192 257 61 61 5
DSG2 DSG2 Q14126 Desmoglein-2 chr18 Not Cancer Driver No 1 hippie, biogrid 173 476 68 68 5
DST_ENST00000370788 DST Q03001-14 Isoform 9 of Dystonin chr6 Not Cancer Driver No 1 hippie, biogrid 729 1895 241 241 0
DTNA_ENST00000444659 DTNA Q9Y4J8 Dystrobrevin alpha chr18 Not Cancer Driver No 1 hippie, biogrid 162 412 86 86 0
ECPAS_ENST00000338205 ECPAS Q5VYK3 Proteasome adapter and scaffold protein ECM29 chr9 Not Cancer Driver No 1 hippie 176 240 22 22 0
EFNB1 EFNB1 P98172 Ephrin-B1 chrX Not Cancer Driver No 1 hippie, biogrid 46 126 14 14 19
EFNB2_ENST00000245323 EFNB2 P52799 Ephrin-B2 chr13 Not Cancer Driver No 1 hippie, biogrid 42 97 15 15 0
EFR3A EFR3A Q14156 Protein EFR3 homolog A chr8 Not Cancer Driver No 1 hippie, biogrid 114 77 10 10 0
EFR3B EFR3B Q9Y2G0 Protein EFR3 homolog B chr2 Not Cancer Driver No 1 hippie, biogrid 42 104 3 3 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie, biogrid 444 223 35 35 1
ELMOD3 ELMOD3 Q96FG2 ELMO domain-containing protein 3 chr2 Not Cancer Driver No 1 hippie, biogrid 39 58 4 4 1
EPB41L1 EPB41L1 Q9H4G0 Band 4.1-like protein 1 chr20 Not Cancer Driver No 1 hippie, biogrid 151 577 109 109 1
EPB41L2_ENST00000368128 EPB41L2 O43491 Band 4.1-like protein 2 chr6 Not Cancer Driver No 1 hippie, biogrid 157 708 113 113 0
EPB41L4A_ENST00000621003 EPB41L4A Q9HCS5 Band 4.1-like protein 4A chr5 Not Cancer Driver No 1 hippie, biogrid 119 378 65 65 0
EPB41L5 EPB41L5 Q9HCM4 Band 4.1-like protein 5 chr2 Not Cancer Driver No 1 hippie, biogrid 97 312 45 45 0
EPHA2 EPHA2 P29317 Ephrin type-A receptor 2 chr1 Compendium Yes 1 hippie, biogrid 171 187 39 39 3
EPHA7 EPHA7 Q15375 Ephrin type-A receptor 7 chr6 Census, Compendium Yes 1 hippie, biogrid 280 71 15 15 0
EPN2 EPN2 O95208 Epsin-2 chr17 Not Cancer Driver No 1 hippie, biogrid 73 543 61 61 0
ESYT2_ENST00000613624 ESYT2 A0FGR8 Extended synaptotagmin-2 chr7 Not Cancer Driver No 1 hippie, biogrid 94 376 25 25 0
F11R F11R Q9Y624 Junctional adhesion molecule A chr1 Not Cancer Driver No 1 hippie, biogrid 47 72 15 15 0
FAM135A_ENST00000370479 FAM135A Q9P2D6 Protein FAM135A chr6 Not Cancer Driver No 1 hippie, biogrid 177 568 57 57 0
FAM83B FAM83B Q5T0W9 Protein FAM83B chr6 Not Cancer Driver No 1 hippie, biogrid 314 684 219 219 0
FAM91A1 FAM91A1 Q658Y4 Protein FAM91A1 chr8 Not Cancer Driver No 1 hippie, biogrid 121 109 6 6 0
FARP1_ENST00000319562 FARP1 Q9Y4F1 FERM, ARHGEF and pleckstrin domain-containing protein 1 chr13 Not Cancer Driver No 1 hippie, biogrid 147 315 60 60 0
FCHO2 FCHO2 Q0JRZ9 F-BAR domain only protein 2 chr5 Not Cancer Driver No 1 hippie, biogrid 79 373 45 45 0
FERMT2_ENST00000395631 FERMT2 Q96AC1 Fermitin family homolog 2 chr14 Not Cancer Driver No 1 hippie, biogrid 71 101 10 10 0
FEZ2_ENST00000405912 FEZ2 Q9UHY8 Fasciculation and elongation protein zeta-2 chr2 Not Cancer Driver No 2 intact, hippie, biogrid 37 245 29 29 0
FGFR4 FGFR4 P22455 Fibroblast growth factor receptor 4 chr5 Census, Compendium Yes 1 intact, hippie 113 162 28 28 0
FKBP4 FKBP4 Q02790 Peptidyl-prolyl cis-trans isomerase FKBP4 chr12 Not Cancer Driver No 1 hippie, biogrid 46 134 12 12 0
FLOT2 FLOT2 Q14254 Flotillin-2 chr17 Not Cancer Driver No 1 hippie, biogrid 56 20 3 3 0
FLVCR1 FLVCR1 Q9Y5Y0 Feline leukemia virus subgroup C receptor-related protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 58 117 14 14 4
FMN2 FMN2 Q9NZ56 Formin-2 chr1 Not Cancer Driver No 1 hippie, biogrid 614 1322 475 475 0
FRS2 FRS2 Q8WU20 Fibroblast growth factor receptor substrate 2 chr12 Not Cancer Driver No 1 hippie, biogrid 69 415 58 58 0
GAB1_ENST00000262994 GAB1 Q13480 GRB2-associated-binding protein 1 chr4 Not Cancer Driver No 1 hippie, biogrid 79 570 68 68 1
GLMN GLMN Q92990 Glomulin chr1 Not Cancer Driver No 1 hippie, biogrid 49 37 6 6 0
GOLGA3_ENST00000450791 GOLGA3 Q08378 Golgin subfamily A member 3 chr12 Not Cancer Driver No 1 hippie, biogrid 221 1272 189 189 0
GOLGA4_ENST00000361924 GOLGA4 Q13439 Golgin subfamily A member 4 chr3 Not Cancer Driver No 1 hippie, biogrid 231 1658 162 162 0
GOPC GOPC Q9HD26 Golgi-associated PDZ and coiled-coil motif-containing protein chr6 Census Yes 1 hippie, biogrid 56 263 34 34 0
GPRIN3_ENST00000333209 GPRIN3 Q6ZVF9 G protein-regulated inducer of neurite outgrowth 3 chr4 Not Cancer Driver No 1 hippie, biogrid 141 749 138 138 0
HECTD1 HECTD1 Q9ULT8 E3 ubiquitin-protein ligase HECTD1 chr14 Not Cancer Driver No 1 hippie, biogrid 274 991 108 108 0
HERC1 HERC1 Q15751 Probable E3 ubiquitin-protein ligase HERC1 chr15 Not Cancer Driver No 1 hippie, biogrid 487 1344 129 129 1
HGS HGS O14964 Hepatocyte growth factor-regulated tyrosine kinase substrate chr17 Not Cancer Driver No 1 hippie, biogrid 109 528 74 74 0
HIP1 HIP1 O00291 Huntingtin-interacting protein 1 chr7 Census, Compendium Yes 1 hippie, biogrid 137 510 70 70 0
HIP1R HIP1R O75146 Huntingtin-interacting protein 1-related protein chr12 Not Cancer Driver No 1 hippie, biogrid 94 524 34 34 0
HLA-A_ENST00000376809 HLA-A P04439 HLA class I histocompatibility antigen, A alpha chain chr6 Census, Compendium Yes 1 hippie, biogrid 128 125 60 60 0
HRAS HRAS P01112 GTPase HRas chr11 Census, Compendium Yes 1 hippie 107 16 4 4 18
HUWE1_ENST00000262854 HUWE1 Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 chrX Not Cancer Driver No 1 hippie, biogrid 669 2091 329 329 21
IGF2R IGF2R P11717 Cation-independent mannose-6-phosphate receptor chr6 Not Cancer Driver No 1 hippie, biogrid 318 255 20 20 0
ILDR2 ILDR2 Q71H61 Immunoglobulin-like domain-containing receptor 2 chr1 Not Cancer Driver No 1 hippie, biogrid 117 355 49 49 0
IPO5_ENST00000490680 IPO5 O00410 Importin-5 chr13 Not Cancer Driver No 1 hippie, biogrid 128 52 3 3 0
IPO7 IPO7 O95373 Importin-7 chr11 Not Cancer Driver No 1 hippie, biogrid 138 202 30 30 0
IPO8 IPO8 O15397 Importin-8 chr12 Not Cancer Driver No 1 hippie, biogrid 130 111 13 13 0
IRS4 IRS4 O14654 Insulin receptor substrate 4 chrX Census, Compendium Yes 1 hippie, biogrid 297 798 203 203 0
ITGA2 ITGA2 P17301 Integrin alpha-2 chr5 Not Cancer Driver No 1 hippie, biogrid 166 26 0 0 0
ITGA6_ENST00000442250 ITGA6 P23229 Integrin alpha-6 chr2 Not Cancer Driver No 1 hippie, biogrid 130 226 29 29 0
ITGB1_ENST00000302278 ITGB1 P05556 Integrin beta-1 chr10 Not Cancer Driver No 1 hippie, biogrid 103 84 10 10 0
JUP JUP P14923 Junction plakoglobin chr17 Not Cancer Driver No 1 hippie, biogrid 112 241 37 37 0
KCNB2 KCNB2 Q92953 Potassium voltage-gated channel subfamily B member 2 chr8 Not Cancer Driver No 1 hippie, biogrid 372 502 200 200 0
KIAA1549 KIAA1549 Q9HCM3 UPF0606 protein KIAA1549 chr7 Census Yes 1 hippie, biogrid 295 1129 169 169 0
KIDINS220 KIDINS220 Q9ULH0 Kinase D-interacting substrate of 220 kDa chr2 Not Cancer Driver No 1 hippie, biogrid 245 683 113 113 0
KIF1B_ENST00000377086 KIF1B O60333 Kinesin-like protein KIF1B chr1 Not Cancer Driver No 1 hippie, biogrid 253 633 106 106 1
KIRREL1 KIRREL1 Q96J84 Kin of IRRE-like protein 1 chr1 Not Cancer Driver No 1 hippie 141 273 57 57 1
KRAS KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 1 intact, hippie 788 7 2 2 27
LEMD3 LEMD3 Q9Y2U8 Inner nuclear membrane protein Man1 chr12 Not Cancer Driver No 1 hippie, biogrid 78 509 33 33 0
LLGL1 LLGL1 Q15334 Lethal(2) giant larvae protein homolog 1 chr17 Not Cancer Driver No 1 hippie, biogrid 101 265 12 12 0
LMNB1 LMNB1 P20700 Lamin-B1 chr5 Not Cancer Driver No 1 hippie, biogrid 60 404 42 42 4
LNPEP LNPEP Q9UIQ6 Leucyl-cystinyl aminopeptidase chr5 Not Cancer Driver No 1 hippie, biogrid 115 103 8 8 0
LRBA LRBA P50851 Lipopolysaccharide-responsive and beige-like anchor protein chr4 Not Cancer Driver No 1 hippie, biogrid 350 709 82 82 1
LRRC49_ENST00000260382 LRRC49 Q8IUZ0 Leucine-rich repeat-containing protein 49 chr15 Not Cancer Driver No 1 hippie, biogrid 117 124 21 21 0
LRRC59 LRRC59 Q96AG4 Leucine-rich repeat-containing protein 59 chr17 Not Cancer Driver No 1 hippie, biogrid 33 122 15 15 0
LSR_ENST00000361790 LSR Q86X29 Lipolysis-stimulated lipoprotein receptor chr19 Not Cancer Driver No 1 hippie, biogrid 89 330 42 42 0
LTV1 LTV1 Q96GA3 Protein LTV1 homolog chr6 Not Cancer Driver No 1 hippie, biogrid 45 388 30 30 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 Census Yes 1 hippie, biogrid 95 84 12 12 0
LZTS2 LZTS2 Q9BRK4 Leucine zipper putative tumor suppressor 2 chr10 Not Cancer Driver No 1 hippie, biogrid 78 508 66 66 0
MAGED2 MAGED2 Q9UNF1 Melanoma-associated antigen D2 chrX Not Cancer Driver No 1 hippie, biogrid 99 326 53 53 1
MAP3K21 MAP3K21 Q5TCX8 Mitogen-activated protein kinase kinase kinase 21 chr1 Not Cancer Driver No 1 hippie 191 658 112 112 0
MAP3K9_ENST00000554752 MAP3K9 P80192 Mitogen-activated protein kinase kinase kinase 9 chr14 Not Cancer Driver No 1 hippie, biogrid 167 684 104 104 0
MAP4K4_ENST00000347699 MAP4K4 O95819 Mitogen-activated protein kinase kinase kinase kinase 4 chr2 Not Cancer Driver No 1 hippie, biogrid 143 649 55 55 0
MAP4K5 MAP4K5 Q9Y4K4 Mitogen-activated protein kinase kinase kinase kinase 5 chr14 Not Cancer Driver No 1 hippie, biogrid 69 236 23 23 0
MARK2 MARK2 Q7KZI7 Serine/threonine-protein kinase MARK2 chr11 Compendium Yes 1 hippie, biogrid 124 445 70 70 0
MARK3 MARK3 P27448 MAP/microtubule affinity-regulating kinase 3 chr14 Not Cancer Driver No 1 hippie, biogrid 92 376 49 49 1
MARVELD2_ENST00000325631 MARVELD2 Q8N4S9 MARVEL domain-containing protein 2 chr5 Not Cancer Driver No 1 hippie, biogrid 74 251 36 36 0
MCAM MCAM P43121 Cell surface glycoprotein MUC18 chr11 Not Cancer Driver No 1 hippie, biogrid 91 305 46 46 0
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 Census, Compendium Yes 1 hippie, biogrid 56 297 37 37 0
MEOX2 MEOX2 P50222 Homeobox protein MOX-2 chr7 Not Cancer Driver No 1 intact, hippie 70 274 63 63 0
MPP1 MPP1 Q00013 55 kDa erythrocyte membrane protein chrX Not Cancer Driver No 1 hippie, biogrid 79 194 33 33 0
MPP7 MPP7 Q5T2T1 MAGUK p55 subfamily member 7 chr10 Not Cancer Driver No 1 hippie, biogrid 132 199 72 72 0
MPZL1 MPZL1 O95297 Myelin protein zero-like protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 36 56 7 7 0
MTIF2_ENST00000403721 MTIF2 P46199 Translation initiation factor IF-2, mitochondrial chr2 Not Cancer Driver No 3 intact, hippie, biogrid 101 112 9 9 0
NAP1L1 NAP1L1 P55209 Nucleosome assembly protein 1-like 1 chr12 Not Cancer Driver No 2 hippie, biogrid 47 207 31 31 0
NAP1L4 NAP1L4 Q99733 Nucleosome assembly protein 1-like 4 chr11 Not Cancer Driver No 1 hippie, biogrid 38 194 19 19 0
NBEA NBEA Q8NFP9 Neurobeachin chr13 Census, Compendium Yes 1 hippie, biogrid 537 717 134 134 4
NBR1 NBR1 Q14596 Next to BRCA1 gene 1 protein chr17 Not Cancer Driver No 1 hippie, biogrid 101 560 51 51 0
NECTIN2 NECTIN2 Q92692 Nectin-2 chr19 Not Cancer Driver No 1 hippie 63 296 29 29 0
NISCH_ENST00000479054 NISCH Q9Y2I1 Nischarin chr3 Not Cancer Driver No 1 hippie, biogrid 160 418 43 43 0
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 Census, Compendium Yes 1 hippie, biogrid 363 686 87 87 3
NOTCH2 NOTCH2 Q04721 Neurogenic locus notch homolog protein 2 chr1 Census, Compendium Yes 1 hippie, biogrid 282 630 77 77 1
NSFL1C_ENST00000216879 NSFL1C Q9UNZ2 NSFL1 cofactor p47 chr20 Not Cancer Driver No 1 hippie, biogrid 56 266 39 39 0
NUDCD3 NUDCD3 Q8IVD9 NudC domain-containing protein 3 chr7 Not Cancer Driver No 1 hippie, biogrid 30 199 16 16 0
NUMBL NUMBL Q9Y6R0 Numb-like protein chr19 Not Cancer Driver No 1 hippie, biogrid 42 467 23 23 0
NUMB_ENST00000355058 NUMB P49757 Protein numb homolog chr14 Not Cancer Driver No 1 hippie, biogrid 70 490 58 58 0
OCLN OCLN Q16625 Occludin chr5 Not Cancer Driver No 1 biogrid 54 244 21 21 1
P4HB P4HB P07237 Protein disulfide-isomerase chr17 Not Cancer Driver No 1 hippie, biogrid 61 79 15 15 1
PACSIN2_ENST00000402229 PACSIN2 Q9UNF0 Protein kinase C and casein kinase substrate in neurons protein 2 chr22 Not Cancer Driver No 1 hippie, biogrid 51 301 27 27 0
PAK4 PAK4 O96013 Serine/threonine-protein kinase PAK 4 chr19 Not Cancer Driver No 1 hippie, biogrid 58 340 33 33 0
PALB2 PALB2 Q86YC2 Partner and localizer of BRCA2 chr16 Census Yes 1 intact, hippie 124 769 77 77 1
PALM PALM O75781 Paralemmin-1 chr19 Not Cancer Driver No 1 hippie, biogrid 50 381 50 50 0
PALM2_ENST00000374531 PALM2 Q8IXS6 Paralemmin-2 chr9 Not Cancer Driver No 1 hippie, biogrid 64 334 56 56 0
PARD3 PARD3 Q8TEW0 Partitioning defective 3 homolog chr10 Not Cancer Driver No 1 hippie, biogrid 200 1144 170 170 2
PCDH7_ENST00000361762 PCDH7 O60245 Protocadherin-7 chr4 Not Cancer Driver No 1 hippie, biogrid 167 550 76 76 0
PCNX3 PCNX3 Q9H6A9 Pecanex-like protein 3 chr11 Not Cancer Driver No 1 hippie 185 839 71 71 0
PEAK1_ENST00000312493 PEAK1 Q9H792 Inactive tyrosine-protein kinase PEAK1 chr15 Not Cancer Driver No 1 hippie, biogrid 222 1232 150 150 0
PEX19 PEX19 P40855 Peroxisomal biogenesis factor 19 chr1 Not Cancer Driver No 1 hippie, biogrid 41 266 38 38 0
PICALM PICALM Q13492 Phosphatidylinositol-binding clathrin assembly protein chr11 Census Yes 1 hippie, biogrid 89 320 42 42 0
PIK3C3 PIK3C3 Q8NEB9 Phosphatidylinositol 3-kinase catalytic subunit type 3 chr18 Not Cancer Driver No 1 hippie 127 191 34 34 0
PKP2 PKP2 Q99959 Plakophilin-2 chr12 Not Cancer Driver No 1 hippie, biogrid 176 434 98 98 8
PKP4 PKP4 Q99569 Plakophilin-4 chr2 Not Cancer Driver No 1 hippie, biogrid 172 756 119 119 0
PLCH1 PLCH1 Q4KWH8 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 chr3 Not Cancer Driver No 1 hippie, biogrid 383 772 195 195 0
PLEKHA1 PLEKHA1 Q9HB21 Pleckstrin homology domain-containing family A member 1 chr10 Not Cancer Driver No 1 hippie, biogrid 61 191 32 32 0
PLEKHA5_ENST00000299275 PLEKHA5 Q9HAU0 Pleckstrin homology domain-containing family A member 5 chr12 Not Cancer Driver No 1 hippie, biogrid 144 869 114 114 0
PPFIA1 PPFIA1 Q13136 Liprin-alpha-1 chr11 Not Cancer Driver No 1 hippie, biogrid 164 865 126 126 0
PPFIBP1 PPFIBP1 Q86W92 Liprin-beta-1 chr12 Census Yes 1 hippie, biogrid 110 555 57 57 0
PPM1D PPM1D O15297 Protein phosphatase 1D chr17 Census, Compendium Yes 1 hippie 54 370 32 32 0
PPM1G PPM1G O15355 Protein phosphatase 1G chr2 Not Cancer Driver No 1 hippie, biogrid 51 359 39 39 0
PPP1CC_ENST00000335007 PPP1CC P36873 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit chr12 Not Cancer Driver No 1 hippie, biogrid 26 23 4 4 0
PSD3_ENST00000440756 PSD3 Q9NYI0 PH and SEC7 domain-containing protein 3 chr8 Not Cancer Driver No 1 hippie, biogrid 146 645 94 94 0
PSMC1 PSMC1 P62191 26S proteasome regulatory subunit 4 chr14 Not Cancer Driver No 1 hippie, biogrid 36 165 10 10 0
PSMC3_ENST00000298852 PSMC3 P17980 26S proteasome regulatory subunit 6A chr11 Not Cancer Driver No 1 hippie, biogrid 55 131 10 10 0
PSMD1 PSMD1 Q99460 26S proteasome non-ATPase regulatory subunit 1 chr2 Not Cancer Driver No 1 hippie, biogrid 110 201 19 19 0
PSMD2 PSMD2 Q13200 26S proteasome non-ATPase regulatory subunit 2 chr3 Not Cancer Driver No 1 hippie, biogrid 100 135 14 14 0
PSMD4_ENST00000368884 PSMD4 P55036 26S proteasome non-ATPase regulatory subunit 4 chr1 Not Cancer Driver No 1 hippie, biogrid 43 243 25 25 0
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 Not Cancer Driver No 1 intact, hippie 49 140 25 25 0
PTPN13_ENST00000411767 PTPN13 Q12923 Tyrosine-protein phosphatase non-receptor type 13 chr4 Census, Compendium Yes 1 hippie, biogrid 299 1231 149 149 0
PTPRG PTPRG P23470 Receptor-type tyrosine-protein phosphatase gamma chr3 Not Cancer Driver No 1 hippie, biogrid 212 465 61 61 0
RAB23_ENST00000317483 RAB23 Q9ULC3 Ras-related protein Rab-23 chr6 Not Cancer Driver No 1 hippie, biogrid 28 62 6 6 2
RAB7A RAB7A P51149 Ras-related protein Rab-7a chr3 Not Cancer Driver No 1 hippie, biogrid 27 11 0 0 4
RALGAPA1_ENST00000389698 RALGAPA1 Q6GYQ0 Ral GTPase-activating protein subunit alpha-1 chr14 Not Cancer Driver No 1 hippie, biogrid 227 649 73 73 1
RAP1GDS1_ENST00000408927 RAP1GDS1 P52306 Rap1 GTPase-GDP dissociation stimulator 1 chr4 Census, Compendium Yes 1 hippie, biogrid 93 13 0 0 0
RASAL2_ENST00000462775 RASAL2 Q9UJF2 Ras GTPase-activating protein nGAP chr1 Not Cancer Driver No 1 hippie, biogrid 164 606 86 86 0
RBM11 RBM11 P57052 Splicing regulator RBM11 chr21 Not Cancer Driver No 1 hippie, biogrid 67 124 38 38 0
RELL1_ENST00000314117 RELL1 Q8IUW5 RELT-like protein 1 chr4 Not Cancer Driver No 1 hippie, biogrid 19 201 11 11 0
RHOA RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie, biogrid 99 46 13 13 2
RICTOR_ENST00000357387 RICTOR Q6R327 Rapamycin-insensitive companion of mTOR chr5 Not Cancer Driver No 1 hippie, biogrid 212 366 50 50 0
RNF19B RNF19B Q6ZMZ0 E3 ubiquitin-protein ligase RNF19B chr1 Not Cancer Driver No 3 hippie, biogrid 58 344 24 24 0
ROR2 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 Not Cancer Driver No 1 hippie, biogrid 203 299 71 71 5
SCAMP1 SCAMP1 O15126 Secretory carrier-associated membrane protein 1 chr5 Not Cancer Driver No 1 hippie, biogrid 29 117 14 14 0
SCAMP3 SCAMP3 O14828 Secretory carrier-associated membrane protein 3 chr1 Not Cancer Driver No 1 hippie, biogrid 46 130 23 23 0
SCARB1_ENST00000415380 SCARB1 Q8WTV0 Scavenger receptor class B member 1 chr12 Not Cancer Driver No 1 hippie, biogrid 53 6 1 1 0
SCRIB_ENST00000320476 SCRIB Q14160 Protein scribble homolog chr8 Not Cancer Driver No 1 hippie, biogrid 196 1064 135 135 2
SCYL2_ENST00000360820 SCYL2 Q6P3W7 SCY1-like protein 2 chr12 Not Cancer Driver No 1 hippie, biogrid 103 328 29 29 0
SEMA4C SEMA4C Q9C0C4 Semaphorin-4C chr2 Not Cancer Driver No 1 hippie, biogrid 111 149 27 27 0
SLC12A2 SLC12A2 P55011 Solute carrier family 12 member 2 chr5 Not Cancer Driver No 1 hippie, biogrid 141 297 18 18 8
SLC12A4_ENST00000316341 SLC12A4 Q9UP95 Solute carrier family 12 member 4 chr16 Not Cancer Driver No 1 hippie, biogrid 122 171 17 17 0
SLC12A7 SLC12A7 Q9Y666 Solute carrier family 12 member 7 chr5 Not Cancer Driver No 1 hippie, biogrid 153 202 23 23 0
SLC19A1 SLC19A1 P41440 Reduced folate transporter chr21 Not Cancer Driver No 1 hippie, biogrid 77 144 7 7 0
SLC1A5 SLC1A5 Q15758 Neutral amino acid transporter B(0) chr19 Not Cancer Driver No 1 hippie, biogrid 52 61 7 7 0
SLC29A1_ENST00000371708 SLC29A1 Q99808 Equilibrative nucleoside transporter 1 chr6 Not Cancer Driver No 1 hippie, biogrid 51 27 4 4 0
SLC30A1 SLC30A1 Q9Y6M5 Zinc transporter 1 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 49 144 9 9 0
SLC38A1_ENST00000546893 SLC38A1 Q9H2H9 Sodium-coupled neutral amino acid transporter 1 chr12 Not Cancer Driver No 1 hippie, biogrid 95 25 4 4 0
SLC38A2 SLC38A2 Q96QD8 Sodium-coupled neutral amino acid transporter 2 chr12 Not Cancer Driver No 1 hippie, biogrid 60 9 1 1 0
SLC39A10_ENST00000359634 SLC39A10 Q9ULF5 Zinc transporter ZIP10 chr2 Not Cancer Driver No 1 hippie, biogrid 111 417 63 63 0
SLC39A14_ENST00000381237 SLC39A14 Q15043 Metal cation symporter ZIP14 chr8 Not Cancer Driver No 1 hippie, biogrid 34 42 3 3 4
SLC39A6_ENST00000590986 SLC39A6 Q13433 Zinc transporter ZIP6 chr18 Not Cancer Driver No 1 hippie, biogrid 86 360 37 37 0
SLC3A2_ENST00000377890 SLC3A2 P08195 4F2 cell-surface antigen heavy chain chr11 Not Cancer Driver No 1 hippie, biogrid 62 171 12 12 0
SLC4A7_ENST00000295736 SLC4A7 Q9Y6M7 Sodium bicarbonate cotransporter 3 chr3 Not Cancer Driver No 1 hippie, biogrid 165 406 57 57 0
SLC6A15 SLC6A15 Q9H2J7 Sodium-dependent neutral amino acid transporter B(0)AT2 chr12 Not Cancer Driver No 1 hippie, biogrid 163 70 22 22 0
SLC6A6_ENST00000622186 SLC6A6 P31641 Sodium- and chloride-dependent taurine transporter chr3 Not Cancer Driver No 1 hippie, biogrid 80 22 1 1 2
SLC6A8 SLC6A8 P48029 Sodium- and chloride-dependent creatine transporter 1 chrX Not Cancer Driver No 1 hippie, biogrid 50 25 1 1 12
SLC7A1 SLC7A1 P30825 High affinity cationic amino acid transporter 1 chr13 Not Cancer Driver No 1 hippie, biogrid 89 17 3 3 0
SLC7A2_ENST00000494857 SLC7A2 P52569 Cationic amino acid transporter 2 chr8 Not Cancer Driver No 1 hippie, biogrid 113 36 6 6 0
SLC7A5 SLC7A5 Q01650 Large neutral amino acids transporter small subunit 1 chr16 Not Cancer Driver No 1 hippie, biogrid 62 35 1 1 0
SLC9A1 SLC9A1 P19634 Sodium/hydrogen exchanger 1 chr1 Not Cancer Driver No 1 hippie, biogrid 89 251 29 29 1
SNAP23 SNAP23 O00161 Synaptosomal-associated protein 23 chr15 Not Cancer Driver No 1 hippie, biogrid 18 179 16 16 0
SNX6 SNX6 Q9UNH7 Sorting nexin-6 chr14 Not Cancer Driver No 1 hippie, biogrid 33 85 7 7 0
SPECC1 SPECC1 Q5M775 Cytospin-B chr17 Census Yes 1 hippie, biogrid 165 833 133 133 0
SPTAN1_ENST00000372731 SPTAN1 Q13813 Spectrin alpha chain, non-erythrocytic 1 chr9 Not Cancer Driver No 1 hippie, biogrid 315 980 114 114 0
SPTBN1 SPTBN1 Q01082 Spectrin beta chain, non-erythrocytic 1 chr2 Not Cancer Driver No 1 hippie, biogrid 311 869 123 123 0
SPTBN2 SPTBN2 O15020 Spectrin beta chain, non-erythrocytic 2 chr11 Not Cancer Driver No 1 hippie, biogrid 317 877 126 126 2
STAM2 STAM2 O75886 Signal transducing adapter molecule 2 chr2 Not Cancer Driver No 1 hippie, biogrid 69 291 30 30 0
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 Census, Compendium Yes 1 hippie 110 152 15 15 19
STEAP3_ENST00000393107 STEAP3 Q658P3 Metalloreductase STEAP3 chr2 Not Cancer Driver No 1 hippie, biogrid 82 30 2 2 0
TBC1D10B TBC1D10B Q4KMP7 TBC1 domain family member 10B chr16 Not Cancer Driver No 1 hippie, biogrid 54 498 27 27 0
TBC1D8_ENST00000376840 TBC1D8 O95759 TBC1 domain family member 8 chr2 Not Cancer Driver No 1 hippie, biogrid 164 224 28 28 0
TC2N_ENST00000340892 TC2N Q8N9U0 Tandem C2 domains nuclear protein chr14 Not Cancer Driver No 1 hippie, biogrid 83 117 21 21 0
TFRC_ENST00000392396 TFRC P02786 Transferrin receptor protein 1 chr3 Census Yes 1 hippie, biogrid 89 80 6 6 1
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 Not Cancer Driver No 1 intact, hippie 41 41 4 4 10
TIAM1 TIAM1 Q13009 Rho guanine nucleotide exchange factor TIAM1 chr21 Not Cancer Driver No 1 hippie, biogrid 370 810 194 194 0
TMEM51_ENST00000376014 TMEM51 Q9NW97 Transmembrane protein 51 chr1 Not Cancer Driver No 1 hippie, biogrid 47 181 37 37 0
TMEM87A TMEM87A Q8NBN3 Transmembrane protein 87A chr15 Not Cancer Driver No 1 hippie, biogrid 60 71 10 10 0
TOR1AIP1_ENST00000606911 TOR1AIP1 Q5JTV8 Torsin-1A-interacting protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 71 401 44 44 0
TPD52L2_ENST00000346249 TPD52L2 O43399 Tumor protein D54 chr20 Not Cancer Driver No 1 hippie, biogrid 25 180 22 22 0
TPGS1 TPGS1 Q6ZTW0 Tubulin polyglutamylase complex subunit 1 chr19 Not Cancer Driver No 1 hippie, biogrid 6 62 2 2 0
TRPM7 TRPM7 Q96QT4 Transient receptor potential cation channel subfamily M member 7 chr15 Not Cancer Driver No 1 hippie, biogrid 199 455 60 60 0
TUBAL3 TUBAL3 A6NHL2 Tubulin alpha chain-like 3 chr10 Not Cancer Driver No 1 hippie, biogrid 85 25 3 3 0
TUBB2B TUBB2B Q9BVA1 Tubulin beta-2B chain chr6 Not Cancer Driver No 1 hippie, biogrid 43 68 10 10 10
TXNL1_ENST00000590954 TXNL1 O43396 Thioredoxin-like protein 1 chr18 Not Cancer Driver No 1 hippie, biogrid 41 89 4 4 0
UBXN4 UBXN4 Q92575 UBX domain-containing protein 4 chr2 Not Cancer Driver No 1 hippie, biogrid 69 302 41 41 0
USP6NL_ENST00000609104 USP6NL Q92738 USP6 N-terminal-like protein chr10 Not Cancer Driver No 1 hippie, biogrid 113 472 81 81 0
VAMP2_ENST00000316509 VAMP2 P63027 Vesicle-associated membrane protein 2 chr17 Not Cancer Driver No 1 hippie, biogrid 7 47 4 4 3
VAMP3 VAMP3 Q15836 Vesicle-associated membrane protein 3 chr1 Not Cancer Driver No 1 hippie, biogrid 11 17 1 1 0
VANGL1 VANGL1 Q8TAA9 Vang-like protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 72 140 15 15 3
VANGL2 VANGL2 Q9ULK5 Vang-like protein 2 chr1 Not Cancer Driver No 1 hippie, biogrid 122 150 37 37 3
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 Not Cancer Driver No 1 hippie, biogrid 88 186 16 16 16
VPS45_ENST00000644510 VPS45 Q9NRW7 Vacuolar protein sorting-associated protein 45 chr1 Not Cancer Driver No 1 hippie, biogrid 66 57 5 5 2
WDR6_ENST00000608424 WDR6 Q9NNW5 WD repeat-containing protein 6 chr3 Not Cancer Driver No 1 hippie, biogrid 166 105 13 13 0
WT1_ENST00000379079 WT1 P19544-6 Isoform 6 of Wilms tumor protein chr11 Census, Compendium Yes 1 hippie 69 194 43 43 0
XPR1 XPR1 Q9UBH6 Xenotropic and polytropic retrovirus receptor 1 chr1 Not Cancer Driver No 1 hippie, biogrid 103 70 15 15 4
YES1_ENST00000314574 YES1 P07947 Tyrosine-protein kinase Yes chr18 Not Cancer Driver No 1 hippie, biogrid 65 62 10 10 0
YKT6 YKT6 O15498 Synaptobrevin homolog YKT6 chr7 Not Cancer Driver No 1 hippie, biogrid 19 21 2 2 0
ZDHHC5 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 Not Cancer Driver No 1 hippie, biogrid 89 462 63 63 0