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DFFA ,DFFA ,O00273
  • Uniprot Accession= O00273
  • Ensembl Transcript= ENST00000377038.7
  • Uniprot Name= DFFA
  • Name= DNA fragmentation factor subunit alpha
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 1
  • Number of Interaction partner in biogrid: 11
  • Number of Interaction partner in hippie: 58
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ATG3 ATG3 Q9NT62 Ubiquitin-like-conjugating enzyme ATG3 chr3 Not Cancer Driver No 1 hippie 29 110 9 9 0
BAK1 BAK1 Q16611 Bcl-2 homologous antagonist/killer chr6 Not Cancer Driver No 1 hippie, biogrid 38 58 9 9 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 193 1182 172 172 0
BZW2_ENST00000258761 BZW2 Q9Y6E2 eIF5-mimic protein 1 chr7 Not Cancer Driver No 1 hippie 41 58 8 8 0
CASP3 CASP3 P42574 Caspase-3 chr4 Census Yes 1 hippie 32 62 5 5 0
CASP7_ENST00000345633 CASP7 P55210 Caspase-7 chr10 Not Cancer Driver No 1 hippie 38 73 10 10 0
CIDEB CIDEB Q9UHD4 Cell death activator CIDE-B chr14 Not Cancer Driver No 1 hippie 19 23 1 1 0
CKB CKB P12277 Creatine kinase B-type chr14 Not Cancer Driver No 1 hippie 31 102 4 4 0
CNBP_ENST00000422453 CNBP P62633 CCHC-type zinc finger nucleic acid binding protein chr3 Census Yes 1 hippie 11 19 0 0 0
CTPS1 CTPS1 P17812 CTP synthase 1 chr1 Not Cancer Driver No 1 hippie 70 83 10 10 0
CYP4B1_ENST00000271153 CYP4B1 P13584 Cytochrome P450 4B1 chr1 Not Cancer Driver No 1 hippie 124 8 2 2 0
DFFA DFFA O00273 DNA fragmentation factor subunit alpha chr1 Not Cancer Driver No 1 hippie 47 113 18 18 0
DFFB_ENST00000378209 DFFB O76075 DNA fragmentation factor subunit beta chr1 Not Cancer Driver No 5 hippie, biogrid 37 27 1 1 0
DUSP12 DUSP12 Q9UNI6 Dual specificity protein phosphatase 12 chr1 Not Cancer Driver No 1 hippie 33 30 1 1 0
EFTUD2 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 132 179 30 30 3
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
EIF5_ENST00000392715 EIF5 P55010 Eukaryotic translation initiation factor 5 chr14 Not Cancer Driver No 1 hippie 64 185 23 23 0
EIF6_ENST00000374436 EIF6 P56537 Eukaryotic translation initiation factor 6 chr20 Not Cancer Driver No 1 hippie 30 17 3 3 0
EWSR1_ENST00000397938 EWSR1 Q01844 RNA-binding protein EWS chr22 Census, Compendium Yes 1 hippie 94 646 93 93 0
FERMT2_ENST00000395631 FERMT2 Q96AC1 Fermitin family homolog 2 chr14 Not Cancer Driver No 1 hippie 71 101 10 10 0
GAPDH GAPDH P04406 Glyceraldehyde-3-phosphate dehydrogenase chr12 Not Cancer Driver No 1 hippie 39 24 3 3 0
GNB4_ENST00000468623 GNB4 Q9HAV0 Guanine nucleotide-binding protein subunit beta-4 chr3 Not Cancer Driver No 1 hippie, biogrid 49 27 3 3 2
GZMB GZMB P10144 Granzyme B chr14 Not Cancer Driver No 1 hippie 49 103 23 23 0
GZMM GZMM P51124 Granzyme M chr19 Not Cancer Driver No 1 hippie 25 12 1 1 0
HERC1 HERC1 Q15751 Probable E3 ubiquitin-protein ligase HERC1 chr15 Not Cancer Driver No 1 hippie, biogrid 487 1344 129 129 1
HNRNPL HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 89 283 29 29 0
HSPB1 HSPB1 P04792 Heat shock protein beta-1 chr7 Not Cancer Driver No 1 hippie 10 118 8 8 20
ISOC1 ISOC1 Q96CN7 Isochorismatase domain-containing protein 1 chr5 Not Cancer Driver No 1 hippie 30 0 0 0 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 hippie 519 90 17 17 23
MAT2A MAT2A P31153 S-adenosylmethionine synthase isoform type-2 chr2 Not Cancer Driver No 1 hippie 36 31 4 4 0
MAT2B MAT2B Q9NZL9 Methionine adenosyltransferase 2 subunit beta chr5 Not Cancer Driver No 1 hippie 42 59 8 8 0
MCC_ENST00000302475 MCC P23508 Colorectal mutant cancer protein chr5 Not Cancer Driver No 1 hippie, biogrid 136 589 92 92 0
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 110 101 8 8 0
NAP1L5 NAP1L5 Q96NT1 Nucleosome assembly protein 1-like 5 chr4 Not Cancer Driver No 1 hippie, biogrid 23 152 18 18 0
NECAB2 NECAB2 Q7Z6G3 N-terminal EF-hand calcium-binding protein 2 chr16 Not Cancer Driver No 1 hippie 46 122 9 9 0
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 Census, Compendium Yes 1 hippie 228 402 62 62 4
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
NXF1_ENST00000294172 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 100 163 32 32 0
PFAS PFAS O15067 Phosphoribosylformylglycinamidine synthase chr17 Not Cancer Driver No 1 hippie 157 380 36 36 0
PPP5C PPP5C P53041 Serine/threonine-protein phosphatase 5 chr19 Not Cancer Driver No 1 hippie 70 73 12 12 0
PRKAA2 PRKAA2 P54646 5'-AMP-activated protein kinase catalytic subunit alpha-2 chr1 Not Cancer Driver No 1 hippie 128 98 26 26 0
PRNP PRNP P04156 Major prion protein chr20 Not Cancer Driver No 1 hippie 36 115 7 7 18
RPS6KA3_ENST00000379565 RPS6KA3 P51812 Ribosomal protein S6 kinase alpha-3 chrX Compendium Yes 1 hippie 106 145 18 18 13
STRN4_ENST00000263280 STRN4 Q9NRL3 Striatin-4 chr19 Not Cancer Driver No 1 hippie 84 407 40 40 0
TMBIM4_ENST00000358230 TMBIM4 Q9HC24 Protein lifeguard 4 chr12 Not Cancer Driver No 1 hippie, biogrid 36 3 0 0 0
TOM1L2 TOM1L2 Q6ZVM7 TOM1-like protein 2 chr17 Not Cancer Driver No 1 hippie, biogrid 57 335 37 37 0
TSPYL4 TSPYL4 Q9UJ04 Testis-specific Y-encoded-like protein 4 chr6 Not Cancer Driver No 3 intact, hippie, biogrid 32 268 17 17 0
TTN_ENST00000615779 TTN Q8WZ42 Titin chr2 Not Cancer Driver No 1 hippie 7917 12926 2861 2861 10
TUBA1A TUBA1A Q71U36 Tubulin alpha-1A chain chr12 Not Cancer Driver No 1 hippie 59 52 11 11 8
TUBB TUBB P07437 Tubulin beta chain chr6 Not Cancer Driver No 1 hippie 40 63 11 11 5
USP15 USP15 Q9Y4E8 Ubiquitin carboxyl-terminal hydrolase 15 chr12 Not Cancer Driver No 1 hippie, biogrid 136 259 39 39 0
UVRAG UVRAG Q9P2Y5 UV radiation resistance-associated gene protein chr11 Not Cancer Driver No 1 hippie 89 243 28 28 0
YWHAB_ENST00000353703 YWHAB P31946 14-3-3 protein beta/alpha chr20 Not Cancer Driver No 1 hippie 22 109 4 4 0
YWHAG YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 1 hippie 26 77 9 9 2
YWHAQ YWHAQ P27348 14-3-3 protein theta chr2 Not Cancer Driver No 1 hippie 29 41 6 6 0
YWHAZ_ENST00000395956 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 2 hippie, biogrid 30 81 10 10 0
ZDHHC5 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 Not Cancer Driver No 1 hippie 89 462 63 63 0