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DEGS1_ENST00000391877 ,DEGS1 ,O15121
  • Uniprot Accession= O15121
  • Ensembl Transcript= ENST00000391877.3
  • Uniprot Name= DEGS1
  • Name= Sphingolipid delta(4)-desaturase DES1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 34
  • Number of Interaction partner in hippie: 52
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
APLNR APLNR P35414 Apelin receptor chr11 Not Cancer Driver No 1 hippie, biogrid 96 29 8 8 0
BSCL2_ENST00000421906 BSCL2 Q96G97 Seipin chr11 Not Cancer Driver No 1 hippie, biogrid 55 125 15 15 5
C4orf3_ENST00000504110 C4orf3 Q8WVX3 Uncharacterized protein C4orf3 chr4 Not Cancer Driver No 3 hippie, biogrid 11 18 5 5 0
CACNG1 CACNG1 Q06432 Voltage-dependent calcium channel gamma-1 subunit chr17 Not Cancer Driver No 1 hippie, biogrid 36 0 0 0 0
CD79A CD79A P11912 B-cell antigen receptor complex-associated protein alpha chain chr19 Census Yes 2 hippie, biogrid 32 28 3 3 0
CLEC2B CLEC2B Q92478 C-type lectin domain family 2 member B chr12 Not Cancer Driver No 1 hippie, biogrid 28 0 0 0 0
COX4I1 COX4I1 P13073 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 17 5 1 1 1
CPLX2_ENST00000515094 CPLX2 Q6PUV4 Complexin-2 chr5 Not Cancer Driver No 2 hippie, biogrid 27 134 27 27 0
CYHR1_ENST00000438911 CYHR1 Q6ZMK1 Cysteine and histidine-rich protein 1 chr8 Not Cancer Driver No 2 hippie, biogrid 24 11 0 0 0
DNAJC25 DNAJC25 Q9H1X3 DnaJ homolog subfamily C member 25 chr9 Not Cancer Driver No 1 hippie, biogrid 37 39 3 3 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 444 223 35 35 1
EIF3E EIF3E P60228 Eukaryotic translation initiation factor 3 subunit E chr8 Census, Compendium Yes 1 hippie 73 27 1 1 0
EIF5B EIF5B O60841 Eukaryotic translation initiation factor 5B chr2 Not Cancer Driver No 2 hippie, biogrid 122 718 71 71 0
EIPR1_ENST00000382125 EIPR1 Q53HC9 EARP and GARP complex-interacting protein 1 chr2 Not Cancer Driver No 1 hippie 52 71 4 4 0
FLOT2 FLOT2 Q14254 Flotillin-2 chr17 Not Cancer Driver No 1 hippie, biogrid 56 20 3 3 0
FOXP4_ENST00000307972 FOXP4 Q8IVH2 Forkhead box protein P4 chr6 Not Cancer Driver No 1 hippie 78 518 55 55 0
GPR12_ENST00000381436 GPR12 P47775 G-protein coupled receptor 12 chr13 Not Cancer Driver No 1 hippie, biogrid 69 0 0 0 0
GPR17 GPR17 Q13304 Uracil nucleotide/cysteinyl leukotriene receptor chr2 Not Cancer Driver No 1 hippie, biogrid 57 16 4 4 0
GTF2F1 GTF2F1 P35269 General transcription factor IIF subunit 1 chr19 Not Cancer Driver No 1 hippie, biogrid 63 426 48 48 0
HDGFL2 HDGFL2 Q7Z4V5 Hepatoma-derived growth factor-related protein 2 chr19 Not Cancer Driver No 1 hippie 59 622 57 57 0
KCNA2_ENST00000638616 KCNA2 P16389 Potassium voltage-gated channel subfamily A member 2 chr1 Not Cancer Driver No 1 hippie, biogrid 96 82 16 16 5
LAMTOR1 LAMTOR1 Q6IAA8 Ragulator complex protein LAMTOR1 chr11 Not Cancer Driver No 1 hippie, biogrid 13 96 7 7 0
LPAR6_ENST00000620633 LPAR6 P43657 Lysophosphatidic acid receptor 6 chr13 Not Cancer Driver No 2 hippie, biogrid 39 0 0 0 3
LSG1 LSG1 Q9H089 Large subunit GTPase 1 homolog chr3 Not Cancer Driver No 1 hippie, biogrid 73 369 42 42 0
MOB1A MOB1A Q9H8S9 MOB kinase activator 1A chr2 Not Cancer Driver No 1 hippie 16 10 2 2 0
NAGPA NAGPA Q9UK23 N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase chr16 Not Cancer Driver No 1 hippie 47 131 11 11 0
NCR3LG1 NCR3LG1 Q68D85 Natural cytotoxicity triggering receptor 3 ligand 1 chr11 Not Cancer Driver No 2 hippie, biogrid 8 70 3 3 0
NRG1_ENST00000405005 NRG1 Q02297 Pro-neuregulin-1, membrane-bound isoform chr8 Census, Compendium Yes 1 hippie, biogrid 159 528 132 132 0
NT5E NT5E P21589 5'-nucleotidase chr6 Not Cancer Driver No 1 hippie, biogrid 61 26 2 2 1
NUDT21 NUDT21 O43809 Cleavage and polyadenylation specificity factor subunit 5 chr16 Not Cancer Driver No 1 hippie 21 37 3 3 0
OPRL1_ENST00000336866 OPRL1 P41146 Nociceptin receptor chr20 Not Cancer Driver No 1 hippie, biogrid 81 0 0 0 0
OPRM1_ENST00000330432 OPRM1 P35372 Mu-type opioid receptor chr6 Not Cancer Driver No 1 hippie, biogrid 107 58 27 27 0
PCMT1_ENST00000464889 PCMT1 A0A0A0MRJ6 Protein-L-isoaspartate O-methyltransferase chr6 Not Cancer Driver No 1 hippie 34 38 4 4 0
PSEN1 PSEN1 P49768 Presenilin-1 chr14 Not Cancer Driver No 1 hippie 61 134 21 21 96
PTH1R_ENST00000449590 PTH1R Q03431 Parathyroid hormone/parathyroid hormone-related peptide receptor chr3 Not Cancer Driver No 2 hippie, biogrid 86 124 25 25 5
PTH2R PTH2R P49190 Parathyroid hormone 2 receptor chr2 Not Cancer Driver No 1 hippie, biogrid 123 49 17 17 0
PYGM PYGM P11217 Glycogen phosphorylase, muscle form chr11 Not Cancer Driver No 1 hippie, biogrid 153 39 4 4 17
RADIL RADIL Q96JH8 Ras-associating and dilute domain-containing protein chr7 Not Cancer Driver No 1 hippie 173 381 62 62 0
RNF4 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 Not Cancer Driver No 1 hippie 14 117 7 7 0
SCARA3 SCARA3 Q6AZY7 Scavenger receptor class A member 3 chr8 Not Cancer Driver No 3 hippie, biogrid 80 230 29 29 0
SEMA4G_ENST00000370250 SEMA4G Q9NTN9 Semaphorin-4G chr10 Not Cancer Driver No 1 hippie 95 285 30 30 0
SF3B3 SF3B3 Q15393 Splicing factor 3B subunit 3 chr16 Not Cancer Driver No 1 hippie 154 145 19 19 0
SHMT2 SHMT2 P34897 Serine hydroxymethyltransferase, mitochondrial chr12 Not Cancer Driver No 1 hippie 57 58 5 5 1
SIRT2 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 Not Cancer Driver No 3 hippie, biogrid 56 85 17 17 0
SLC16A1 SLC16A1 P53985 Monocarboxylate transporter 1 chr1 Not Cancer Driver No 1 hippie, biogrid 69 70 3 3 3
SLC17A2_ENST00000265425 SLC17A2 O00624 Sodium-dependent phosphate transport protein 3 chr6 Not Cancer Driver No 2 hippie, biogrid 81 12 5 5 0
SUPT6H SUPT6H Q7KZ85 Transcription elongation factor SPT6 chr17 Not Cancer Driver No 1 hippie, biogrid 222 761 107 107 0
SURF4 SURF4 O15260 Surfeit locus protein 4 chr9 Not Cancer Driver No 1 hippie, biogrid 29 0 0 0 0
TCTN3 TCTN3 Q6NUS6 Tectonic-3 chr10 Not Cancer Driver No 1 hippie 45 71 8 8 1
TGFA_ENST00000295400 TGFA P01135 Protransforming growth factor alpha chr2 Not Cancer Driver No 1 hippie, biogrid 20 0 0 0 0
UBD UBD O15205 Ubiquitin D chr6 Not Cancer Driver No 1 hippie 31 8 1 1 0
UFD1 UFD1 Q92890 Ubiquitin recognition factor in ER-associated degradation protein 1 chr22 Not Cancer Driver No 1 hippie 26 100 7 7 0