Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
A2M | A2M | P01023 | Alpha-2-macroglobulin | chr12 | Not Cancer Driver | No | 1 | hippie | 260 | 144 | 22 | 22 | 0 |
AGO2 | AGO2 | Q9UKV8 | Protein argonaute-2 | chr8 | Not Cancer Driver | No | 2 | intact, hippie | 126 | 141 | 15 | 15 | 11 |
ALDH3A2_ENST00000579855 | ALDH3A2 | P51648 | Aldehyde dehydrogenase family 3 member A2 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 47 | 5 | 2 | 2 | 26 |
ANO7 | ANO7 | Q6IWH7 | Anoctamin-7 | chr2 | Not Cancer Driver | No | 1 | hippie | 144 | 147 | 32 | 32 | 0 |
AP3B1 | AP3B1 | O00203 | AP-3 complex subunit beta-1 | chr5 | Not Cancer Driver | No | 1 | hippie | 126 | 316 | 31 | 31 | 1 |
APP | APP | P05067 | Amyloid-beta precursor protein | chr21 | Not Cancer Driver | No | 1 | hippie | 128 | 418 | 71 | 71 | 17 |
ASXL1_ENST00000613218 | ASXL1 | Q8IXJ9 | Polycomb group protein ASXL1 | chr20 | Census, Compendium | Yes | 1 | hippie | 205 | 1300 | 174 | 174 | 0 |
ATRX | ATRX | P46100 | Transcriptional regulator ATRX | chrX | Census, Compendium | Yes | 2 | intact, hippie | 487 | 1672 | 301 | 301 | 33 |
AURKB_ENST00000585124 | AURKB | Q96GD4 | Aurora kinase B | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 63 | 8 | 8 | 0 |
BAD_ENST00000309032 | BAD | Q92934 | Bcl2-associated agonist of cell death | chr11 | Not Cancer Driver | No | 1 | hippie | 14 | 163 | 14 | 14 | 0 |
BARD1 | BARD1 | Q99728 | BRCA1-associated RING domain protein 1 | chr2 | Census | Yes | 1 | hippie | 96 | 384 | 49 | 49 | 0 |
BCR | BCR | P11274 | Breakpoint cluster region protein | chr22 | Census, Compendium | Yes | 1 | hippie, biogrid | 146 | 603 | 69 | 69 | 0 |
BRD7_ENST00000394688 | BRD7 | Q9NPI1 | Bromodomain-containing protein 7 | chr16 | Compendium | Yes | 1 | hippie | 82 | 482 | 57 | 57 | 0 |
BRF2 | BRF2 | Q9HAW0 | Transcription factor IIIB 50 kDa subunit | chr8 | Not Cancer Driver | No | 1 | hippie | 40 | 138 | 13 | 13 | 0 |
CAPRIN1_ENST00000532820 | CAPRIN1 | Q14444 | Caprin-1 | chr11 | Not Cancer Driver | No | 1 | hippie | 84 | 603 | 72 | 72 | 0 |
CCNF | CCNF | P41002 | Cyclin-F | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 106 | 221 | 23 | 23 | 3 |
CCT2 | CCT2 | P78371 | T-complex protein 1 subunit beta | chr12 | Not Cancer Driver | No | 1 | hippie | 63 | 46 | 3 | 3 | 0 |
CCT6A | CCT6A | P40227 | T-complex protein 1 subunit zeta | chr7 | Not Cancer Driver | No | 1 | hippie | 66 | 5 | 1 | 1 | 0 |
CCT7 | CCT7 | Q99832 | T-complex protein 1 subunit eta | chr2 | Not Cancer Driver | No | 1 | hippie | 59 | 36 | 6 | 6 | 0 |
CD2BP2 | CD2BP2 | O95400 | CD2 antigen cytoplasmic tail-binding protein 2 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 49 | 259 | 40 | 40 | 0 |
CEP131 | CEP131 | Q9UPN4 | Centrosomal protein of 131 kDa | chr17 | Not Cancer Driver | No | 1 | hippie | 126 | 948 | 113 | 113 | 0 |
CIAO1 | CIAO1 | O76071 | Probable cytosolic iron-sulfur protein assembly protein CIAO1 | chr2 | Not Cancer Driver | No | 1 | hippie | 30 | 20 | 2 | 2 | 0 |
CIT_ENST00000261833 | CIT | O14578 | Citron Rho-interacting kinase | chr12 | Not Cancer Driver | No | 1 | hippie | 284 | 1017 | 160 | 160 | 3 |
CLN3_ENST00000636147 | CLN3 | Q13286 | Battenin | chr16 | Not Cancer Driver | No | 1 | intact, hippie | 58 | 69 | 10 | 10 | 9 |
CNOT9_ENST00000273064 | CNOT9 | Q92600 | CCR4-NOT transcription complex subunit 9 | chr2 | Compendium | Yes | 1 | hippie | 42 | 30 | 0 | 0 | 0 |
COIL | COIL | P38432 | Coilin | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 61 | 385 | 42 | 42 | 0 |
COMTD1 | COMTD1 | Q86VU5 | Catechol O-methyltransferase domain-containing protein 1 | chr10 | Not Cancer Driver | No | 2 | hippie, biogrid | 11 | 23 | 0 | 0 | 0 |
COPA_ENST00000241704 | COPA | P53621 | Coatomer subunit alpha | chr1 | Not Cancer Driver | No | 1 | hippie | 163 | 157 | 18 | 18 | 4 |
COPS5 | COPS5 | Q92905 | COP9 signalosome complex subunit 5 | chr8 | Not Cancer Driver | No | 1 | hippie | 36 | 32 | 7 | 7 | 0 |
CPSF7_ENST00000394888 | CPSF7 | Q8N684 | Cleavage and polyadenylation specificity factor subunit 7 | chr11 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 55 | 398 | 52 | 52 | 0 |
CRY2_ENST00000616080 | CRY2 | Q49AN0 | Cryptochrome-2 | chr11 | Not Cancer Driver | No | 1 | hippie | 72 | 100 | 12 | 12 | 0 |
CRYAB_ENST00000616970 | CRYAB | P02511 | Alpha-crystallin B chain | chr11 | Not Cancer Driver | No | 2 | hippie, biogrid | 22 | 59 | 11 | 11 | 4 |
CSNK1E | CSNK1E | P49674 | Casein kinase I isoform epsilon | chr22 | Not Cancer Driver | No | 1 | hippie | 62 | 133 | 18 | 18 | 0 |
CTBP1 | CTBP1 | Q13363 | C-terminal-binding protein 1 | chr4 | Not Cancer Driver | No | 1 | intact, hippie | 42 | 123 | 9 | 9 | 1 |
DCLRE1C | DCLRE1C | Q96SD1 | Protein artemis | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 76 | 277 | 26 | 26 | 3 |
DDRGK1 | DDRGK1 | Q96HY6 | DDRGK domain-containing protein 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 34 | 181 | 23 | 23 | 0 |
DDX20 | DDX20 | Q9UHI6 | Probable ATP-dependent RNA helicase DDX20 | chr1 | Not Cancer Driver | No | 1 | hippie | 89 | 299 | 33 | 33 | 0 |
DHX9 | DHX9 | Q08211 | ATP-dependent RNA helicase A | chr1 | Compendium | Yes | 1 | hippie | 182 | 331 | 42 | 42 | 0 |
DICER1 | DICER1 | Q9UPY3 | Endoribonuclease Dicer | chr14 | Census, Compendium | Yes | 1 | intact, hippie | 264 | 362 | 45 | 45 | 4 |
DISC1_ENST00000439617 | DISC1 | Q9NRI5 | Disrupted in schizophrenia 1 protein | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 132 | 514 | 82 | 82 | 0 |
DNM2_ENST00000355667 | DNM2 | P50570 | Dynamin-2 | chr19 | Census | Yes | 1 | intact, hippie | 138 | 270 | 43 | 43 | 22 |
DYRK2 | DYRK2 | Q92630 | Dual specificity tyrosine-phosphorylation-regulated kinase 2 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 77 | 294 | 39 | 39 | 0 |
EAF1 | EAF1 | Q96JC9 | ELL-associated factor 1 | chr3 | Not Cancer Driver | No | 2 | intact, hippie | 17 | 257 | 17 | 17 | 0 |
ECT2 | ECT2 | Q9H8V3 | Protein ECT2 | chr3 | Not Cancer Driver | No | 1 | hippie | 104 | 284 | 33 | 33 | 0 |
EFTUD2 | EFTUD2 | Q15029 | 116 kDa U5 small nuclear ribonucleoprotein component | chr17 | Compendium | Yes | 1 | hippie | 132 | 179 | 30 | 30 | 3 |
EGFR | EGFR | P00533 | Epidermal growth factor receptor | chr7 | Census, Compendium | Yes | 1 | hippie | 444 | 223 | 35 | 35 | 1 |
EGLN3 | EGLN3 | Q9H6Z9 | Prolyl hydroxylase EGLN3 | chr14 | Not Cancer Driver | No | 1 | hippie | 33 | 13 | 0 | 0 | 0 |
EIF2AK1 | EIF2AK1 | Q9BQI3 | Eukaryotic translation initiation factor 2-alpha kinase 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 87 | 238 | 29 | 29 | 0 |
ERF | ERF | P50548 | ETS domain-containing transcription factor ERF | chr19 | Not Cancer Driver | No | 1 | hippie | 74 | 398 | 54 | 54 | 3 |
ESR1_ENST00000206249 | ESR1 | P03372 | Estrogen receptor | chr6 | Census, Compendium | Yes | 1 | intact, hippie | 121 | 195 | 27 | 27 | 2 |
ESR2 | ESR2 | Q92731 | Estrogen receptor beta | chr14 | Not Cancer Driver | No | 1 | hippie | 90 | 92 | 11 | 11 | 1 |
ETV3 | ETV3 | P41162 | ETS translocation variant 3 | chr1 | Not Cancer Driver | No | 1 | hippie | 48 | 330 | 24 | 24 | 0 |
EWSR1_ENST00000397938 | EWSR1 | Q01844 | RNA-binding protein EWS | chr22 | Census, Compendium | Yes | 1 | hippie | 94 | 646 | 93 | 93 | 0 |
FA2H | FA2H | Q7L5A8 | Fatty acid 2-hydroxylase | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 33 | 73 | 0 | 0 | 3 |
FAM120C | FAM120C | Q9NX05 | Constitutive coactivator of PPAR-gamma-like protein 2 | chrX | Not Cancer Driver | No | 1 | hippie | 162 | 508 | 77 | 77 | 0 |
FAXC | FAXC | Q5TGI0 | Failed axon connections homolog | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 47 | 54 | 11 | 11 | 0 |
FBL | FBL | P22087 | rRNA 2'-O-methyltransferase fibrillarin | chr19 | Not Cancer Driver | No | 1 | hippie | 46 | 145 | 22 | 22 | 0 |
FGF14_ENST00000376143 | FGF14 | Q92915 | Fibroblast growth factor 14 | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 72 | 93 | 30 | 30 | 1 |
FUS | FUS | P35637 | RNA-binding protein FUS | chr16 | Census | Yes | 1 | hippie | 51 | 524 | 51 | 51 | 20 |
FZR1 | FZR1 | Q9UM11 | Fizzy-related protein homolog | chr19 | Not Cancer Driver | No | 1 | hippie | 74 | 184 | 30 | 30 | 0 |
GAPDHS | GAPDHS | O14556 | Glyceraldehyde-3-phosphate dehydrogenase, testis-specific | chr19 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 71 | 111 | 19 | 19 | 0 |
GAR1 | GAR1 | Q9NY12 | H/ACA ribonucleoprotein complex subunit 1 | chr4 | Not Cancer Driver | No | 1 | hippie | 23 | 141 | 14 | 14 | 0 |
GDAP1 | GDAP1 | Q8TB36 | Ganglioside-induced differentiation-associated protein 1 | chr8 | Not Cancer Driver | No | 1 | intact, hippie | 51 | 78 | 14 | 14 | 11 |
GEMIN2 | GEMIN2 | O14893 | Gem-associated protein 2 | chr14 | Not Cancer Driver | No | 5 | intact, hippie, biogrid | 39 | 99 | 6 | 6 | 0 |
GEMIN4 | GEMIN4 | P57678 | Gem-associated protein 4 | chr17 | Not Cancer Driver | No | 7 | intact, hippie, biogrid | 101 | 24 | 1 | 1 | 0 |
GEMIN5 | GEMIN5 | Q8TEQ6 | Gem-associated protein 5 | chr5 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 157 | 419 | 54 | 54 | 5 |
GEMIN6 | GEMIN6 | Q8WXD5 | Gem-associated protein 6 | chr2 | Not Cancer Driver | No | 4 | hippie, biogrid | 19 | 71 | 12 | 12 | 0 |
GEMIN7_ENST00000591607 | GEMIN7 | Q9H840 | Gem-associated protein 7 | chr19 | Not Cancer Driver | No | 4 | hippie, biogrid | 32 | 48 | 7 | 7 | 0 |
GEMIN8_ENST00000398355 | GEMIN8 | Q9NWZ8 | Gem-associated protein 8 | chrX | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 42 | 126 | 29 | 29 | 0 |
GIGYF2_ENST00000409547 | GIGYF2 | Q6Y7W6 | GRB10-interacting GYF protein 2 | chr2 | Not Cancer Driver | No | 1 | hippie | 176 | 1096 | 158 | 158 | 6 |
GOLGA2_ENST00000611957 | GOLGA2 | Q08379 | Golgin subfamily A member 2 | chr9 | Not Cancer Driver | No | 1 | hippie | 115 | 854 | 96 | 96 | 0 |
GPR17 | GPR17 | Q13304 | Uracil nucleotide/cysteinyl leukotriene receptor | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 57 | 16 | 4 | 4 | 0 |
GSK3B_ENST00000264235 | GSK3B | P49841 | Glycogen synthase kinase-3 beta | chr3 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 56 | 146 | 13 | 13 | 0 |
HAX1 | HAX1 | O00165 | HCLS1-associated protein X-1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 44 | 219 | 32 | 32 | 2 |
HCST | HCST | Q9UBK5 | Hematopoietic cell signal transducer | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 6 | 12 | 0 | 0 | 0 |
HDAC11 | HDAC11 | Q96DB2 | Histone deacetylase 11 | chr3 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 57 | 18 | 8 | 8 | 0 |
HDAC2 | HDAC2 | Q92769 | Histone deacetylase 2 | chr6 | Not Cancer Driver | No | 1 | hippie | 46 | 145 | 14 | 14 | 0 |
HDAC5_ENST00000586802 | HDAC5 | Q9UQL6 | Histone deacetylase 5 | chr17 | Not Cancer Driver | No | 1 | hippie | 118 | 718 | 73 | 73 | 0 |
HSCB | HSCB | Q8IWL3 | Iron-sulfur cluster co-chaperone protein HscB | chr22 | Not Cancer Driver | No | 1 | intact, hippie | 36 | 25 | 6 | 6 | 0 |
HTT | HTT | P42858 | Huntingtin | chr4 | Not Cancer Driver | No | 1 | intact, hippie | 336 | 666 | 69 | 69 | 2 |
ITCH | ITCH | Q96J02 | E3 ubiquitin-protein ligase Itchy homolog | chr20 | Not Cancer Driver | No | 1 | hippie | 95 | 335 | 42 | 42 | 0 |
JUN | JUN | P05412 | Transcription factor Jun | chr1 | Census | Yes | 1 | hippie | 35 | 281 | 25 | 25 | 0 |
KDM6B_ENST00000448097 | KDM6B | O15054 | Lysine-specific demethylase 6B | chr17 | Not Cancer Driver | No | 1 | hippie | 189 | 1278 | 142 | 142 | 2 |
KIF14 | KIF14 | Q15058 | Kinesin-like protein KIF14 | chr1 | Not Cancer Driver | No | 1 | hippie | 222 | 774 | 102 | 102 | 2 |
KIF23 | KIF23 | Q02241 | Kinesin-like protein KIF23 | chr15 | Not Cancer Driver | No | 1 | hippie | 102 | 559 | 62 | 62 | 0 |
LMBR1L | LMBR1L | Q6UX01 | Protein LMBR1L | chr12 | Not Cancer Driver | No | 1 | hippie | 57 | 4 | 0 | 0 | 0 |
LRRK2 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | Not Cancer Driver | No | 1 | intact | 519 | 90 | 17 | 17 | 23 |
LSM1 | LSM1 | O15116 | U6 snRNA-associated Sm-like protein LSm1 | chr8 | Not Cancer Driver | No | 1 | hippie | 21 | 6 | 1 | 1 | 0 |
LSM11 | LSM11 | P83369 | U7 snRNA-associated Sm-like protein LSm11 | chr5 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 34 | 266 | 17 | 17 | 1 |
LSM2 | LSM2 | Q9Y333 | U6 snRNA-associated Sm-like protein LSm2 | chr6 | Not Cancer Driver | No | 1 | hippie | 10 | 3 | 0 | 0 | 0 |
LSM4 | LSM4 | Q9Y4Z0 | U6 snRNA-associated Sm-like protein LSm4 | chr19 | Not Cancer Driver | No | 1 | hippie | 19 | 64 | 9 | 9 | 0 |
MAP1LC3A_ENST00000397709 | MAP1LC3A | Q9H492 | Microtubule-associated proteins 1A/1B light chain 3A | chr20 | Not Cancer Driver | No | 1 | hippie | 22 | 24 | 1 | 1 | 0 |
MAPRE3 | MAPRE3 | Q9UPY8 | Microtubule-associated protein RP/EB family member 3 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 120 | 16 | 16 | 0 |
MCM3_ENST00000229854 | MCM3 | P25205 | DNA replication licensing factor MCM3 | chr6 | Not Cancer Driver | No | 2 | intact, hippie | 92 | 310 | 47 | 47 | 0 |
MECP2_ENST00000303391 | MECP2 | P51608 | Methyl-CpG-binding protein 2 | chrX | Not Cancer Driver | No | 1 | intact, hippie | 75 | 483 | 74 | 74 | 46 |
MED29_ENST00000599213 | MED29 | Q9NX70 | Mediator of RNA polymerase II transcription subunit 29 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 21 | 119 | 10 | 10 | 0 |
MFAP1 | MFAP1 | P55081 | Microfibrillar-associated protein 1 | chr15 | Not Cancer Driver | No | 1 | hippie | 58 | 377 | 53 | 53 | 0 |
MFSD4A | MFSD4A | Q8N468 | Major facilitator superfamily domain-containing protein 4A | chr1 | Not Cancer Driver | No | 1 | hippie | 56 | 29 | 3 | 3 | 0 |
MTX2 | MTX2 | O75431 | Metaxin-2 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 33 | 0 | 0 | 0 | 0 |
MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | Census, Compendium | Yes | 1 | hippie | 80 | 299 | 46 | 46 | 0 |
MYO6 | MYO6 | Q9UM54 | Unconventional myosin-VI | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 176 | 342 | 41 | 41 | 3 |
N4BP2 | N4BP2 | Q86UW6 | NEDD4-binding protein 2 | chr4 | Census | Yes | 1 | hippie | 185 | 965 | 104 | 104 | 0 |
NAF1 | NAF1 | Q96HR8 | H/ACA ribonucleoprotein complex non-core subunit NAF1 | chr4 | Not Cancer Driver | No | 2 | intact, hippie | 61 | 386 | 44 | 44 | 0 |
NANOG | NANOG | Q9H9S0 | Homeobox protein NANOG | chr12 | Not Cancer Driver | No | 1 | hippie | 46 | 169 | 35 | 35 | 0 |
NCBP1 | NCBP1 | Q09161 | Nuclear cap-binding protein subunit 1 | chr9 | Not Cancer Driver | No | 2 | intact, hippie | 88 | 89 | 8 | 8 | 0 |
NCBP2_ENST00000427641 | NCBP2 | P52298-3 | Isoform 3 of Nuclear cap-binding protein subunit 2 | chr3 | Not Cancer Driver | No | 1 | hippie | 21 | 61 | 9 | 9 | 0 |
NCBP3 | NCBP3 | Q53F19 | Nuclear cap-binding protein subunit 3 | chr17 | Not Cancer Driver | No | 1 | hippie | 52 | 507 | 42 | 42 | 0 |
NCKIPSD | NCKIPSD | Q9NZQ3 | NCK-interacting protein with SH3 domain | chr3 | Census | Yes | 1 | intact, hippie | 63 | 260 | 28 | 28 | 0 |
NCOR1 | NCOR1 | O75376 | Nuclear receptor corepressor 1 | chr17 | Census, Compendium | Yes | 1 | hippie | 352 | 2347 | 340 | 340 | 0 |
NCOR2 | NCOR2 | Q9Y618 | Nuclear receptor corepressor 2 | chr12 | Census, Compendium | Yes | 1 | hippie | 373 | 2355 | 356 | 356 | 0 |
NPAS1_ENST00000449844 | NPAS1 | Q99742 | Neuronal PAS domain-containing protein 1 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 53 | 309 | 23 | 23 | 0 |
NPTN | NPTN | Q9Y639 | Neuroplastin | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 47 | 118 | 9 | 9 | 0 |
NR0B2 | NR0B2 | Q15466 | Nuclear receptor subfamily 0 group B member 2 | chr1 | Not Cancer Driver | No | 1 | hippie | 35 | 10 | 2 | 2 | 0 |
NR2C2_ENST00000393102 | NR2C2 | P49116 | Nuclear receptor subfamily 2 group C member 2 | chr3 | Not Cancer Driver | No | 1 | hippie | 62 | 186 | 24 | 24 | 0 |
NSD2_ENST00000382892 | NSD2 | O96028 | Histone-lysine N-methyltransferase NSD2 | chr4 | Census, Compendium | Yes | 1 | hippie | 191 | 552 | 76 | 76 | 0 |
NTRK1 | NTRK1 | P04629 | High affinity nerve growth factor receptor | chr1 | Census, Compendium | Yes | 1 | hippie | 168 | 57 | 8 | 8 | 25 |
NUFIP1 | NUFIP1 | Q9UHK0 | Nuclear fragile X mental retardation-interacting protein 1 | chr13 | Not Cancer Driver | No | 1 | hippie | 72 | 403 | 49 | 49 | 0 |
OASL | OASL | Q15646 | 2'-5'-oligoadenylate synthase-like protein | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 76 | 8 | 4 | 4 | 0 |
P2RY10 | P2RY10 | O00398 | Putative P2Y purinoceptor 10 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 113 | 0 | 0 | 0 | 0 |
P2RY12 | P2RY12 | Q9H244 | P2Y purinoceptor 12 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 57 | 21 | 2 | 2 | 3 |
P2RY6_ENST00000540342 | P2RY6 | Q15077 | P2Y purinoceptor 6 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 50 | 10 | 5 | 5 | 0 |
PAK4 | PAK4 | O96013 | Serine/threonine-protein kinase PAK 4 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 340 | 33 | 33 | 0 |
PARP16 | PARP16 | Q8N5Y8 | Protein mono-ADP-ribosyltransferase PARP16 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 33 | 3 | 3 | 0 |
PARP2 | PARP2 | Q9UGN5 | Poly [ADP-ribose] polymerase 2 | chr14 | Not Cancer Driver | No | 1 | intact, hippie | 74 | 172 | 23 | 23 | 0 |
PFN1 | PFN1 | P07737 | Profilin-1 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 7 | 1 | 1 | 3 |
PFN2 | PFN2 | P35080 | Profilin-2 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 0 | 0 | 0 | 0 |
PHAX | PHAX | Q9H814 | Phosphorylated adapter RNA export protein | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 32 | 331 | 29 | 29 | 0 |
PHB2 | PHB2 | Q99623 | Prohibitin-2 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 26 | 4 | 4 | 0 |
PLCD3 | PLCD3 | Q8N3E9 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 61 | 229 | 22 | 22 | 0 |
PLEKHA4 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 136 | 687 | 128 | 128 | 0 |
PLEKHA7 | PLEKHA7 | Q6IQ23 | Pleckstrin homology domain-containing family A member 7 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 152 | 919 | 121 | 121 | 0 |
PNKP | PNKP | Q96T60 | Bifunctional polynucleotide phosphatase/kinase | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 53 | 177 | 23 | 23 | 4 |
POLD1_ENST00000440232 | POLD1 | P28340 | DNA polymerase delta catalytic subunit | chr19 | Census, Compendium | Yes | 1 | hippie | 179 | 214 | 31 | 31 | 2 |
POLR1E | POLR1E | Q9GZS1 | DNA-directed RNA polymerase I subunit RPA49 | chr9 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 39 | 85 | 6 | 6 | 0 |
POLR2C | POLR2C | P19387 | DNA-directed RNA polymerase II subunit RPB3 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 108 | 11 | 11 | 0 |
POMK | POMK | Q9H5K3 | Protein O-mannose kinase | chr8 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 53 | 30 | 9 | 9 | 3 |
POU5F1 | POU5F1 | Q01860 | POU domain, class 5, transcription factor 1 | chr6 | Census | Yes | 1 | hippie | 36 | 186 | 12 | 12 | 0 |
PPP4R2 | PPP4R2 | Q9NY27 | Serine/threonine-protein phosphatase 4 regulatory subunit 2 | chr3 | Not Cancer Driver | No | 1 | hippie | 32 | 314 | 26 | 26 | 0 |
PRKAB1 | PRKAB1 | Q9Y478 | 5'-AMP-activated protein kinase subunit beta-1 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 39 | 124 | 13 | 13 | 0 |
PRRC2A_ENST00000376007 | PRRC2A | P48634 | Protein PRRC2A | chr6 | Not Cancer Driver | No | 1 | hippie | 253 | 2119 | 249 | 249 | 0 |
PSEN1 | PSEN1 | P49768 | Presenilin-1 | chr14 | Not Cancer Driver | No | 1 | intact, hippie | 61 | 134 | 21 | 21 | 96 |
PSKH1 | PSKH1 | P11801 | Serine/threonine-protein kinase H1 | chr16 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 56 | 122 | 24 | 24 | 0 |
PSKH2 | PSKH2 | Q96QS6 | Serine/threonine-protein kinase H2 | chr8 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 86 | 87 | 19 | 19 | 0 |
PTP4A3_ENST00000521578 | PTP4A3 | O75365 | Protein tyrosine phosphatase type IVA 3 | chr8 | Not Cancer Driver | No | 1 | intact, hippie | 30 | 3 | 0 | 0 | 0 |
PTPN9 | PTPN9 | P43378 | Tyrosine-protein phosphatase non-receptor type 9 | chr15 | Not Cancer Driver | No | 1 | hippie | 77 | 78 | 5 | 5 | 0 |
PXN_ENST00000228307 | PXN | P49023 | Paxillin | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 62 | 341 | 24 | 24 | 0 |
RB1CC1 | RB1CC1 | Q8TDY2 | RB1-inducible coiled-coil protein 1 | chr8 | Not Cancer Driver | No | 1 | hippie | 202 | 578 | 75 | 75 | 0 |
RBM14 | RBM14 | Q96PK6 | RNA-binding protein 14 | chr11 | Not Cancer Driver | No | 1 | hippie | 99 | 350 | 59 | 59 | 0 |
RC3H2_ENST00000357244 | RC3H2 | Q9HBD1 | Roquin-2 | chr9 | Not Cancer Driver | No | 1 | hippie | 128 | 703 | 81 | 81 | 0 |
RDX_ENST00000343115 | RDX | P35241 | Radixin | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 71 | 297 | 37 | 37 | 1 |
RNPS1_ENST00000301730 | RNPS1 | Q15287 | RNA-binding protein with serine-rich domain 1 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 30 | 305 | 30 | 30 | 0 |
RPS6KL1_ENST00000557413 | RPS6KL1 | Q9Y6S9 | Ribosomal protein S6 kinase-like 1 | chr14 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 60 | 161 | 16 | 16 | 0 |
SCN2B | SCN2B | O60939 | Sodium channel subunit beta-2 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 46 | 52 | 7 | 7 | 2 |
SEC16A | SEC16A | O15027 | Protein transport protein Sec16A | chr9 | Not Cancer Driver | No | 1 | hippie | 285 | 1923 | 235 | 235 | 0 |
SIGLECL1 | SIGLECL1 | Q8N7X8 | SIGLEC family-like protein 1 | chr19 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 56 | 35 | 14 | 14 | 0 |
SIN3A_ENST00000360439 | SIN3A | Q96ST3 | Paired amphipathic helix protein Sin3a | chr15 | Compendium | Yes | 1 | hippie | 172 | 617 | 73 | 73 | 0 |
SIRT7 | SIRT7 | Q9NRC8 | NAD-dependent protein deacetylase sirtuin-7 | chr17 | Not Cancer Driver | No | 1 | hippie | 48 | 163 | 15 | 15 | 0 |
SLC15A3 | SLC15A3 | Q8IY34 | Solute carrier family 15 member 3 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 63 | 43 | 1 | 1 | 0 |
SLC16A11 | SLC16A11 | Q8NCK7 | Monocarboxylate transporter 11 | chr17 | Not Cancer Driver | No | 1 | hippie | 33 | 72 | 5 | 5 | 0 |
SLX1A_ENST00000345535 | SLX1A | Q9BQ83-2 | Isoform 2 of Structure-specific endonuclease subunit SLX1 | chr16 | Not Cancer Driver | No | 1 | hippie | 5 | 27 | 0 | 0 | 0 |
SLX1B | SLX1B | Q9BQ83 | Structure-specific endonuclease subunit SLX1 | chr16 | Not Cancer Driver | No | 1 | biogrid | 3 | 80 | 1 | 1 | 0 |
SMN1_ENST00000503079 | SMN1 | Q16637-2 | Isoform SMN-delta5 of Survival motor neuron protein | chr5 | Not Cancer Driver | No | 9 | intact, hippie, biogrid | 2 | 181 | 2 | 2 | 0 |
SMN2_ENST00000380741 | SMN2 | Q16637 | Survival motor neuron protein | chr5 | Not Cancer Driver | No | 2 | biogrid | 1 | 220 | 1 | 1 | 18 |
SNAI1 | SNAI1 | O95863 | Zinc finger protein SNAI1 | chr20 | Not Cancer Driver | No | 1 | hippie | 52 | 97 | 11 | 11 | 0 |
SNRNP70 | SNRNP70 | P08621 | U1 small nuclear ribonucleoprotein 70 kDa | chr19 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 38 | 416 | 37 | 37 | 0 |
SNRPB | SNRPB | P14678 | Small nuclear ribonucleoprotein-associated proteins B and B' | chr20 | Not Cancer Driver | No | 2 | hippie, biogrid | 39 | 182 | 34 | 34 | 4 |
SNRPD1 | SNRPD1 | P62314 | Small nuclear ribonucleoprotein Sm D1 | chr18 | Not Cancer Driver | No | 1 | hippie | 10 | 80 | 4 | 4 | 0 |
SNRPD2_ENST00000588301 | SNRPD2 | P62316 | Small nuclear ribonucleoprotein Sm D2 | chr19 | Not Cancer Driver | No | 2 | hippie, biogrid | 19 | 67 | 12 | 12 | 0 |
SNRPD3 | SNRPD3 | P62318 | Small nuclear ribonucleoprotein Sm D3 | chr22 | Not Cancer Driver | No | 1 | hippie | 20 | 43 | 13 | 13 | 0 |
SNRPE | SNRPE | P62304 | Small nuclear ribonucleoprotein E | chr1 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 16 | 0 | 0 | 0 | 1 |
SNRPF | SNRPF | P62306 | Small nuclear ribonucleoprotein F | chr12 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 4 | 10 | 0 | 0 | 0 |
SNRPG_ENST00000272348 | SNRPG | P62308 | Small nuclear ribonucleoprotein G | chr2 | Not Cancer Driver | No | 3 | hippie, biogrid | 8 | 9 | 3 | 3 | 0 |
SNRPN_ENST00000577565 | SNRPN | P63162 | Small nuclear ribonucleoprotein-associated protein N | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 92 | 184 | 79 | 79 | 0 |
SNUPN_ENST00000564675 | SNUPN | O95149 | Snurportin-1 | chr15 | Not Cancer Driver | No | 1 | hippie | 45 | 137 | 17 | 17 | 0 |
SRP54 | SRP54 | P61011 | Signal recognition particle 54 kDa protein | chr14 | Not Cancer Driver | No | 1 | hippie | 53 | 115 | 13 | 13 | 7 |
STAT5A_ENST00000590949 | STAT5A | P42229 | Signal transducer and activator of transcription 5A | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 89 | 125 | 14 | 14 | 0 |
STAU1 | STAU1 | O95793 | Double-stranded RNA-binding protein Staufen homolog 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 77 | 456 | 63 | 63 | 0 |
STRAP | STRAP | Q9Y3F4 | Serine-threonine kinase receptor-associated protein | chr12 | Not Cancer Driver | No | 4 | hippie, biogrid | 44 | 40 | 5 | 5 | 0 |
STXBP2_ENST00000221283 | STXBP2 | Q15833 | Syntaxin-binding protein 2 | chr19 | Not Cancer Driver | No | 1 | hippie | 77 | 80 | 13 | 13 | 5 |
STXBP3 | STXBP3 | O00186 | Syntaxin-binding protein 3 | chr1 | Not Cancer Driver | No | 1 | hippie | 59 | 64 | 9 | 9 | 0 |
SUMO2 | SUMO2 | P61956 | Small ubiquitin-related modifier 2 | chr17 | Not Cancer Driver | No | 1 | hippie | 9 | 69 | 6 | 6 | 0 |
SYNCRIP | SYNCRIP | O60506 | Heterogeneous nuclear ribonucleoprotein Q | chr6 | Not Cancer Driver | No | 1 | hippie | 93 | 285 | 39 | 39 | 0 |
TACSTD2 | TACSTD2 | P09758 | Tumor-associated calcium signal transducer 2 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 22 | 27 | 1 | 1 | 0 |
TCF3 | TCF3 | P15923 | Transcription factor E2-alpha | chr19 | Census | Yes | 1 | hippie | 52 | 649 | 52 | 52 | 0 |
TIA1 | TIA1 | P31483 | Cytotoxic granule associated RNA binding protein TIA1 | chr2 | Not Cancer Driver | No | 1 | hippie | 39 | 130 | 12 | 12 | 2 |
TMPRSS11B | TMPRSS11B | Q86T26 | Transmembrane protease serine 11B | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 95 | 5 | 0 | 0 | 0 |
TMPRSS2_ENST00000458356 | TMPRSS2 | O15393 | Transmembrane protease serine 2 | chr21 | Census | Yes | 1 | hippie, biogrid | 66 | 25 | 5 | 5 | 0 |
TOP3B_ENST00000357179 | TOP3B | O95985 | DNA topoisomerase 3-beta-1 | chr22 | Not Cancer Driver | No | 1 | hippie | 102 | 151 | 17 | 17 | 0 |
TOR1A | TOR1A | O14656 | Torsin-1A | chr9 | Not Cancer Driver | No | 1 | hippie | 33 | 0 | 0 | 0 | 3 |
TP53BP1_ENST00000263801 | TP53BP1 | Q12888 | TP53-binding protein 1 | chr15 | Not Cancer Driver | No | 1 | intact, hippie | 227 | 1632 | 190 | 190 | 0 |
TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | Census, Compendium | Yes | 1 | hippie | 2891 | 282 | 1466 | 1466 | 83 |
TRIM25 | TRIM25 | Q14258 | E3 ubiquitin/ISG15 ligase TRIM25 | chr17 | Not Cancer Driver | No | 1 | hippie | 59 | 225 | 20 | 20 | 0 |
TYRO3 | TYRO3 | Q06418 | Tyrosine-protein kinase receptor TYRO3 | chr15 | Not Cancer Driver | No | 1 | intact | 119 | 197 | 17 | 17 | 0 |
UBD | UBD | O15205 | Ubiquitin D | chr6 | Not Cancer Driver | No | 1 | hippie | 31 | 8 | 1 | 1 | 0 |
UBL4A | UBL4A | P11441 | Ubiquitin-like protein 4A | chrX | Not Cancer Driver | No | 1 | hippie | 22 | 16 | 5 | 5 | 0 |
UFL1 | UFL1 | O94874 | E3 UFM1-protein ligase 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 109 | 141 | 24 | 24 | 0 |
UNC93B1 | UNC93B1 | Q9H1C4 | Protein unc-93 homolog B1 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 57 | 127 | 5 | 5 | 0 |
USO1_ENST00000514213 | USO1 | O60763 | General vesicular transport factor p115 | chr4 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 78 | 368 | 28 | 28 | 0 |
USP7 | USP7 | Q93009 | Ubiquitin carboxyl-terminal hydrolase 7 | chr16 | Not Cancer Driver | No | 1 | intact | 170 | 215 | 45 | 45 | 0 |
USP9X_ENST00000378308 | USP9X | Q93008 | Probable ubiquitin carboxyl-terminal hydrolase FAF-X | chrX | Census, Compendium | Yes | 1 | hippie | 339 | 405 | 51 | 51 | 1 |
WRAP53 | WRAP53 | Q9BUR4 | Telomerase Cajal body protein 1 | chr17 | Not Cancer Driver | No | 1 | hippie | 66 | 232 | 29 | 29 | 4 |
ZFP36L2 | ZFP36L2 | P47974 | mRNA decay activator protein ZFP36L2 | chr2 | Not Cancer Driver | No | 1 | hippie | 73 | 324 | 45 | 45 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
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