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DBT ,DBT ,P11182
  • Uniprot Accession= P11182
  • Ensembl Transcript= ENST00000370132.8
  • Uniprot Name= DBT
  • Name= Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 49
  • Number of Interaction partner in biogrid: 103
  • Number of Interaction partner in hippie: 188
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AARS2 AARS2 Q5JTZ9 Alanine--tRNA ligase, mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 123 203 25 25 5
ABCC1 ABCC1 P33527 Multidrug resistance-associated protein 1 chr16 Not Cancer Driver No 1 hippie, biogrid 199 123 22 22 1
ACAA2 ACAA2 P42765 3-ketoacyl-CoA thiolase, mitochondrial chr18 Not Cancer Driver No 1 hippie, biogrid 42 51 2 2 0
ACAD9 ACAD9 Q9H845 Complex I assembly factor ACAD9, mitochondrial chr3 Not Cancer Driver No 4 intact, hippie, biogrid 69 28 5 5 12
ACOT13 ACOT13 Q9NPJ3 Acyl-coenzyme A thioesterase 13 chr6 Not Cancer Driver No 1 hippie, biogrid 15 23 2 2 0
ADI1 ADI1 Q9BV57 Acireductone dioxygenase chr2 Not Cancer Driver No 1 hippie, biogrid 27 23 1 1 0
AGMAT AGMAT Q9BSE5 Agmatinase, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 53 106 10 10 0
AGO3 AGO3 Q9H9G7 Protein argonaute-3 chr1 Not Cancer Driver No 1 intact, hippie 110 143 19 19 0
AGO4 AGO4 Q9HCK5 Protein argonaute-4 chr1 Not Cancer Driver No 1 intact, hippie 100 183 24 24 0
AIFM1 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX Not Cancer Driver No 1 hippie, biogrid 88 166 22 22 11
AIMP2 AIMP2 Q13155 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 chr7 Not Cancer Driver No 1 hippie 46 61 8 8 0
ALDOA_ENST00000643777 ALDOA P04075 Fructose-bisphosphate aldolase A chr16 Not Cancer Driver No 1 intact 47 65 9 9 3
ATG16L1 ATG16L1 Q676U5 Autophagy-related protein 16-1 chr2 Not Cancer Driver No 1 hippie 79 239 25 25 1
ATXN3 ATXN3 P54252 Ataxin-3 chr14 Not Cancer Driver No 1 hippie 46 181 24 24 0
AUH AUH Q13825 Methylglutaconyl-CoA hydratase, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 34 29 0 0 1
BCKDHB BCKDHB P21953 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial chr6 Not Cancer Driver No 2 intact, hippie, biogrid 47 23 3 3 5
BICD1 BICD1 Q96G01 Protein bicaudal D homolog 1 chr12 Not Cancer Driver No 1 hippie 124 656 86 86 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
BMI1 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 1 intact, hippie 50 150 30 30 0
BRD1_ENST00000216267 BRD1 O95696 Bromodomain-containing protein 1 chr22 Not Cancer Driver No 1 hippie 171 425 68 68 0
BRD7_ENST00000394688 BRD7 Q9NPI1 Bromodomain-containing protein 7 chr16 Compendium Yes 1 hippie 82 482 57 57 0
BRPF3 BRPF3 Q9ULD4 Bromodomain and PHD finger-containing protein 3 chr6 Not Cancer Driver No 1 hippie 143 633 74 74 0
C17orf80_ENST00000535032 C17orf80 Q9BSJ5 Uncharacterized protein C17orf80 chr17 Not Cancer Driver No 1 hippie, biogrid 64 455 53 53 0
CA5B_ENST00000454127 CA5B Q9Y2D0 Carbonic anhydrase 5B, mitochondrial chrX Not Cancer Driver No 2 hippie, biogrid 40 28 2 2 0
CCDC90B CCDC90B Q9GZT6 Coiled-coil domain-containing protein 90B, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 31 76 6 6 0
CDO1 CDO1 Q16878 Cysteine dioxygenase type 1 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 37 43 4 4 0
CECR2_ENST00000342247 CECR2 Q9BXF3 Cat eye syndrome critical region protein 2 chr22 Not Cancer Driver No 1 hippie 222 1192 183 183 0
CEP128_ENST00000281129 CEP128 Q6ZU80 Centrosomal protein of 128 kDa chr14 Not Cancer Driver No 1 hippie 195 897 167 167 0
CEP152 CEP152 O94986 Centrosomal protein of 152 kDa chr15 Not Cancer Driver No 1 intact, hippie 204 986 110 110 2
CEP164 CEP164 Q9UPV0 Centrosomal protein of 164 kDa chr11 Not Cancer Driver No 1 intact, hippie 161 1198 124 124 2
CHCHD2 CHCHD2 Q9Y6H1 Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 chr7 Not Cancer Driver No 1 intact, hippie 24 114 21 21 1
CNTRL_ENST00000238341 CNTRL Q7Z7A1 Centriolin chr9 Census Yes 1 hippie 234 1556 159 159 0
COQ8A COQ8A Q8NI60 Atypical kinase COQ8A, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 95 166 29 29 12
COX4I1 COX4I1 P13073 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial chr16 Not Cancer Driver No 3 intact, hippie, biogrid 17 5 1 1 1
COX5B COX5B P10606 Cytochrome c oxidase subunit 5B, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 16 58 6 6 0
COX8A COX8A P10176 Cytochrome c oxidase subunit 8A, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 10 1 0 0 0
CS CS O75390 Citrate synthase, mitochondrial chr12 Not Cancer Driver No 2 hippie, biogrid 50 13 2 2 0
CSK_ENST00000439220 CSK P41240 Tyrosine-protein kinase CSK chr15 Not Cancer Driver No 1 hippie 41 18 1 1 0
CSNK1A1_ENST00000377843 CSNK1A1 P48729 Casein kinase I isoform alpha chr5 Not Cancer Driver No 1 hippie 44 46 3 3 0
DCAF11 DCAF11 Q8TEB1 DDB1- and CUL4-associated factor 11 chr14 Not Cancer Driver No 2 intact, hippie, biogrid 89 149 25 25 0
DCAF15 DCAF15 Q66K64 DDB1- and CUL4-associated factor 15 chr19 Not Cancer Driver No 1 hippie 50 173 18 18 0
DDX1 DDX1 Q92499 ATP-dependent RNA helicase DDX1 chr2 Not Cancer Driver No 1 intact, hippie 82 91 15 15 0
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 Not Cancer Driver No 1 hippie 118 61 10 10 2
DLD DLD P09622 Dihydrolipoyl dehydrogenase, mitochondrial chr7 Not Cancer Driver No 4 intact, hippie, biogrid 67 17 0 0 10
DLST DLST P36957 Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial chr14 Not Cancer Driver No 1 hippie, biogrid 53 190 32 32 1
DNAJB13 DNAJB13 P59910 DnaJ homolog subfamily B member 13 chr11 Not Cancer Driver No 1 hippie, biogrid 57 42 14 14 1
DNM1L_ENST00000549701 DNM1L O00429 Dynamin-1-like protein chr12 Not Cancer Driver No 1 hippie 67 212 23 23 7
DPF2_ENST00000528416 DPF2 Q92785 Zinc finger protein ubi-d4 chr11 Not Cancer Driver No 1 hippie 67 179 30 30 5
DYNC1I1 DYNC1I1 O14576 Cytoplasmic dynein 1 intermediate chain 1 chr7 Not Cancer Driver No 1 hippie 146 255 60 60 0
DYNLRB1 DYNLRB1 Q9NP97 Dynein light chain roadblock-type 1 chr20 Not Cancer Driver No 1 hippie 23 19 4 4 0
DYNLT1 DYNLT1 P63172 Dynein light chain Tctex-type 1 chr6 Not Cancer Driver No 1 hippie 7 1 0 0 0
ECH1 ECH1 Q13011 Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial chr19 Not Cancer Driver No 1 hippie, biogrid 35 23 2 2 0
ECHDC2 ECHDC2 Q86YB7 Enoyl-CoA hydratase domain-containing protein 2, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 43 10 1 1 0
ECHS1 ECHS1 P30084 Enoyl-CoA hydratase, mitochondrial chr10 Not Cancer Driver No 3 hippie, biogrid 51 7 1 1 14
EMC2 EMC2 Q15006 ER membrane protein complex subunit 2 chr8 Not Cancer Driver No 1 hippie 48 29 3 3 0
EPB41L5 EPB41L5 Q9HCM4 Band 4.1-like protein 5 chr2 Not Cancer Driver No 1 hippie, biogrid 97 312 45 45 0
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
EXD2 EXD2 Q9NVH0 Exonuclease 3'-5' domain-containing protein 2 chr14 Not Cancer Driver No 1 hippie, biogrid 58 176 15 15 0
FAHD1_ENST00000427358 FAHD1 Q6P587 Acylpyruvase FAHD1, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 15 12 0 0 0
FAHD2A FAHD2A Q96GK7 Fumarylacetoacetate hydrolase domain-containing protein 2A chr2 Not Cancer Driver No 3 intact, hippie, biogrid 39 8 2 2 0
FAHD2B FAHD2B Q6P2I3 Fumarylacetoacetate hydrolase domain-containing protein 2B chr2 Not Cancer Driver No 1 hippie, biogrid 44 4 3 3 0
FAM133A_ENST00000332647 FAM133A Q8N9E0 Protein FAM133A chrX Not Cancer Driver No 1 hippie, biogrid 59 248 59 59 0
FAM136A FAM136A Q96C01 Protein FAM136A chr2 Not Cancer Driver No 1 intact, hippie 17 13 1 1 0
FAM160A2_ENST00000449352 FHIP1B Q8N612 FHF complex subunit HOOK interacting protein 1B chr11 Not Cancer Driver No 1 intact 129 415 54 54 0
FAM160B1 FHIP2A Q5W0V3 FHF complex subunit HOOK interacting protein 2A chr10 Not Cancer Driver No 1 intact 92 130 13 13 0
FAM160B2 FHIP2B Q86V87 FHF complex subunit HOOK interacting protein 2B chr8 Not Cancer Driver No 1 intact 75 139 14 14 0
FASTKD3 FASTKD3 Q14CZ7 FAST kinase domain-containing protein 3, mitochondrial chr5 Not Cancer Driver No 1 hippie, biogrid 106 6 1 1 0
FASTKD5 FASTKD5 Q7L8L6 FAST kinase domain-containing protein 5, mitochondrial chr20 Not Cancer Driver No 1 hippie, biogrid 86 94 8 8 0
FH FH P07954 Fumarate hydratase, mitochondrial chr1 Census, Compendium Yes 1 hippie, biogrid 67 76 5 5 13
FOXQ1 FOXQ1 Q9C009 Forkhead box protein Q1 chr6 Not Cancer Driver No 1 intact, hippie 22 245 4 4 0
GATM GATM P50440 Glycine amidinotransferase, mitochondrial chr15 Not Cancer Driver No 1 hippie, biogrid 69 33 8 8 15
GBF1 GBF1 Q92538 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 chr10 Not Cancer Driver No 1 hippie 216 669 76 76 0
GFM1_ENST00000486715 GFM1 Q96RP9 Elongation factor G, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 74 79 7 7 4
GFM2_ENST00000509430 GFM2 Q969S9 Ribosome-releasing factor 2, mitochondrial chr5 Not Cancer Driver No 1 hippie, biogrid 75 100 10 10 2
GRPEL2 GRPEL2 Q8TAA5 GrpE protein homolog 2, mitochondrial chr5 Not Cancer Driver No 3 intact, hippie, biogrid 17 45 3 3 0
GRSF1 GRSF1 Q12849 G-rich sequence factor 1 chr4 Not Cancer Driver No 1 hippie, biogrid 49 147 20 20 0
HDAC6_ENST00000426196 HDAC6 Q9UBN7 Histone deacetylase 6 chrX Not Cancer Driver No 2 intact, hippie, biogrid 178 409 59 59 0
HECTD1 HECTD1 Q9ULT8 E3 ubiquitin-protein ligase HECTD1 chr14 Not Cancer Driver No 1 hippie 274 991 108 108 0
HINT2 HINT2 Q9BX68 Adenosine 5'-monophosphoramidase HINT2 chr9 Not Cancer Driver No 2 hippie, biogrid 10 29 2 2 0
HMGCL HMGCL P35914 Hydroxymethylglutaryl-CoA lyase, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 17 8 2 2 19
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 Not Cancer Driver No 1 intact, hippie 77 504 45 45 0
HOGA1 HOGA1 Q86XE5 4-hydroxy-2-oxoglutarate aldolase, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 34 2 0 0 2
HOOK1 HOOK1 Q9UJC3 Protein Hook homolog 1 chr1 Not Cancer Driver No 1 hippie 97 427 59 59 0
HSD17B10 HSD17B10 Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 chrX Not Cancer Driver No 1 hippie, biogrid 27 15 3 3 11
HUWE1_ENST00000262854 HUWE1 Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 chrX Not Cancer Driver No 1 hippie 669 2091 329 329 21
IDH3B_ENST00000380843 IDH3B O43837 Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial chr20 Not Cancer Driver No 3 intact, hippie, biogrid 32 49 3 3 1
IFIT2_ENST00000371826 IFIT2 P09913 Interferon-induced protein with tetratricopeptide repeats 2 chr10 Not Cancer Driver No 1 intact, hippie 73 85 17 17 0
ISCA2 ISCA2 Q86U28 Iron-sulfur cluster assembly 2 homolog, mitochondrial chr14 Not Cancer Driver No 1 hippie, biogrid 13 38 3 3 1
JUN JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 35 281 25 25 0
LACTB LACTB P83111 Serine beta-lactamase-like protein LACTB, mitochondrial chr15 Not Cancer Driver No 1 intact, hippie 44 121 3 3 0
LIPT1 LIPT1 Q9Y234 Lipoyltransferase 1, mitochondrial chr2 Not Cancer Driver No 3 hippie, biogrid 34 0 0 0 3
LRPPRC LRPPRC P42704 Leucine-rich PPR motif-containing protein, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 131 18 2 2 1
LYRM4_ENST00000330636 LYRM4 Q9HD34 LYR motif-containing protein 4 chr6 Not Cancer Driver No 1 intact, hippie 14 11 1 1 1
MCAT MCAT Q8IVS2 Malonyl-CoA-acyl carrier protein transacylase, mitochondrial chr22 Not Cancer Driver No 1 hippie, biogrid 38 52 2 2 0
MCEE MCEE Q96PE7 Methylmalonyl-CoA epimerase, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 19 9 0 0 0
MCUB MCUB Q9NWR8 Calcium uniporter regulatory subunit MCUb, mitochondrial chr4 Not Cancer Driver No 1 hippie 33 24 1 1 0
MDH2 MDH2 P40926 Malate dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 39 8 1 1 3
MECR MECR Q9BV79 Enoyl-[acyl-carrier-protein] reductase, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 55 26 5 5 3
MED4 MED4 Q9NPJ6 Mediator of RNA polymerase II transcription subunit 4 chr13 Not Cancer Driver No 1 hippie 29 161 17 17 0
METTL15 METTL15 A6NJ78 12S rRNA N4-methylcytidine (m4C) methyltransferase chr11 Not Cancer Driver No 1 hippie, biogrid 46 92 14 14 0
METTL17_ENST00000339374 METTL17 Q9H7H0 Methyltransferase-like protein 17, mitochondrial chr14 Not Cancer Driver No 1 hippie, biogrid 62 95 16 16 0
MICU3 MICU3 Q86XE3 Calcium uptake protein 3, mitochondrial chr8 Not Cancer Driver No 1 hippie, biogrid 72 89 8 8 0
MKS1 MKS1 Q9NXB0 Meckel syndrome type 1 protein chr17 Not Cancer Driver No 1 intact, hippie 82 152 23 23 2
MMAB MMAB Q96EY8 Corrinoid adenosyltransferase MMAB chr12 Not Cancer Driver No 1 hippie, biogrid 36 68 14 14 5
MRPL11 MRPL11 Q9Y3B7 39S ribosomal protein L11, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 25 12 1 1 0
MRPL18 MRPL18 Q9H0U6 39S ribosomal protein L18, mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 26 35 2 2 0
MRPL53 MRPL53 Q96EL3 39S ribosomal protein L53, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 20 22 1 1 0
MRPL58 MRPL58 Q14197 Peptidyl-tRNA hydrolase ICT1, mitochondrial chr17 Not Cancer Driver No 1 hippie 28 105 13 13 0
MRPS11 MRPS11 P82912 28S ribosomal protein S11, mitochondrial chr15 Not Cancer Driver No 2 intact, hippie, biogrid 23 114 12 12 0
MRPS18C MRPS18C Q9Y3D5 28S ribosomal protein S18c, mitochondrial chr4 Not Cancer Driver No 1 hippie, biogrid 16 5 1 1 0
MRPS26 MRPS26 Q9BYN8 28S ribosomal protein S26, mitochondrial chr20 Not Cancer Driver No 1 hippie, biogrid 18 102 6 6 0
MRPS36 MRPS36 P82909 Alpha-ketoglutarate dehydrogenase component 4 chr5 Not Cancer Driver No 1 hippie, biogrid 12 103 12 12 0
MRPS6 MRPS6 P82932 28S ribosomal protein S6, mitochondrial chr21 Not Cancer Driver No 1 hippie, biogrid 17 13 1 1 0
MRRF MRRF Q96E11 Ribosome-recycling factor, mitochondrial chr9 Not Cancer Driver No 4 intact, hippie, biogrid 23 118 9 9 0
MSRB2 MSRB2 Q9Y3D2 Methionine-R-sulfoxide reductase B2, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 17 65 6 6 0
MTERF3 MTERF3 Q96E29 Transcription termination factor 3, mitochondrial chr8 Not Cancer Driver No 1 hippie, biogrid 53 62 5 5 0
MTG2 MTG2 Q9H4K7 Mitochondrial ribosome-associated GTPase 2 chr20 Not Cancer Driver No 1 hippie, biogrid 57 47 9 9 0
MTIF2_ENST00000403721 MTIF2 P46199 Translation initiation factor IF-2, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 101 112 9 9 0
MTIF3_ENST00000381120 MTIF3 Q9H2K0 Translation initiation factor IF-3, mitochondrial chr13 Not Cancer Driver No 1 hippie, biogrid 26 180 19 19 0
MTRF1 MTRF1 O75570 Peptide chain release factor 1, mitochondrial chr13 Not Cancer Driver No 2 hippie, biogrid 50 71 9 9 0
MTRF1L MTRF1L Q9UGC7 Peptide chain release factor 1-like, mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 31 183 12 12 0
MYO6 MYO6 Q9UM54 Unconventional myosin-VI chr6 Not Cancer Driver No 1 hippie 176 342 41 41 3
NABP1 NABP1 Q96AH0 SOSS complex subunit B2 chr2 Not Cancer Driver No 1 intact, hippie 25 102 11 11 0
NABP2_ENST00000341463 NABP2 Q9BQ15 SOSS complex subunit B1 chr12 Not Cancer Driver No 1 intact, hippie 25 125 17 17 0
NCAPD3 NCAPD3 P42695 Condensin-2 complex subunit D3 chr11 Not Cancer Driver No 1 hippie 193 304 42 42 1
NDUFS6 NDUFS6 O75380 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial chr5 Not Cancer Driver No 1 hippie, biogrid 20 8 0 0 1
NF2 NF2 P35240 Merlin chr22 Census, Compendium Yes 1 hippie 69 252 26 26 16
NFKB1_ENST00000505458 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 Not Cancer Driver No 1 intact, hippie 104 344 38 38 0
NIN NIN Q8N4C6 Ninein chr14 Census, Compendium Yes 1 hippie 239 1392 164 164 2
NIPSNAP3B NIPSNAP3B Q9BS92 Protein NipSnap homolog 3B chr9 Not Cancer Driver No 1 hippie, biogrid 31 15 1 1 0
NOCT NOCT Q9UK39 Nocturnin chr4 Not Cancer Driver No 1 intact, hippie 33 89 3 3 0
NPHP1_ENST00000393272 NPHP1 O15259 Nephrocystin-1 chr2 Not Cancer Driver No 1 hippie 108 259 32 32 1
NR2C2_ENST00000393102 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 hippie 62 186 24 24 0
NR3C1_ENST00000343796 NR3C1 P04150 Glucocorticoid receptor chr5 Not Cancer Driver No 1 hippie 92 362 37 37 12
NUDT6 NUDT6 P53370 Nucleoside diphosphate-linked moiety X motif 6 chr4 Not Cancer Driver No 1 hippie, biogrid 40 14 0 0 0
OGT OGT O15294 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit chrX Not Cancer Driver No 1 hippie 156 89 16 16 2
OXLD1 OXLD1 Q5BKU9 Oxidoreductase-like domain-containing protein 1 chr17 Not Cancer Driver No 1 hippie, biogrid 23 84 17 17 0
PCBD2_ENST00000254908 PCBD2 Q9H0N5 Pterin-4-alpha-carbinolamine dehydratase 2 chr5 Not Cancer Driver No 1 hippie, biogrid 6 3 0 0 0
PDHA1_ENST00000422285 PDHA1 P08559 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial chrX Not Cancer Driver No 1 hippie, biogrid 70 43 6 6 20
PDP1_ENST00000297598 PDP1 Q9P0J1 [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial chr8 Not Cancer Driver No 1 hippie, biogrid 64 96 9 9 0
PGR PGR P06401 Progesterone receptor chr11 Not Cancer Driver No 1 intact, hippie 161 480 55 55 0
PHIP PHIP Q8WWQ0 PH-interacting protein chr6 Not Cancer Driver No 1 hippie 239 835 110 110 0
PHYHIPL PHYHIPL Q96FC7 Phytanoyl-CoA hydroxylase-interacting protein-like chr10 Not Cancer Driver No 1 intact, hippie 49 68 9 9 0
PMPCA PMPCA Q10713 Mitochondrial-processing peptidase subunit alpha chr9 Not Cancer Driver No 1 hippie, biogrid 67 23 3 3 4
PMPCB PMPCB O75439 Mitochondrial-processing peptidase subunit beta chr7 Not Cancer Driver No 1 hippie, biogrid 55 22 3 3 5
PPM1K PPM1K Q8N3J5 Protein phosphatase 1K, mitochondrial chr4 Not Cancer Driver No 5 intact, hippie, biogrid 59 62 12 12 0
PPP6C_ENST00000373547 PPP6C O00743 Serine/threonine-protein phosphatase 6 catalytic subunit chr9 Census, Compendium Yes 1 intact, hippie 63 0 0 0 0
PPT1 PPT1 P50897 Palmitoyl-protein thioesterase 1 chr1 Not Cancer Driver No 1 hippie 37 0 0 0 23
PPTC7 PPTC7 Q8NI37 Protein phosphatase PTC7 homolog chr12 Not Cancer Driver No 2 hippie, biogrid 32 36 2 2 0
PRDM4 PRDM4 Q9UKN5 PR domain zinc finger protein 4 chr12 Not Cancer Driver No 1 hippie, biogrid 92 362 40 40 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 Not Cancer Driver No 1 hippie 72 124 17 17 0
PRKD2_ENST00000291281 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 Compendium Yes 1 hippie 118 246 34 34 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 Not Cancer Driver No 1 hippie 110 78 15 15 31
PRSS35 PRSS35 Q8N3Z0 Inactive serine protease 35 chr6 Not Cancer Driver No 1 intact, hippie 97 115 29 29 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 Census, Compendium Yes 1 hippie 505 76 4 4 41
RAB17 RAB17 Q9H0T7 Ras-related protein Rab-17 chr2 Not Cancer Driver No 1 hippie, biogrid 29 43 4 4 0
RALB RALB P11234 Ras-related protein Ral-B chr2 Not Cancer Driver No 2 intact, hippie, biogrid 36 35 5 5 0
RBM5 RBM5 P52756 RNA-binding protein 5 chr3 Not Cancer Driver No 1 hippie, biogrid 94 537 67 67 0
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 138 608 71 71 1
RHOG_ENST00000396978 RHOG P84095 Rho-related GTP-binding protein RhoG chr11 Not Cancer Driver No 1 hippie 26 22 5 5 0
RHOH_ENST00000617441 RHOH Q15669 Rho-related GTP-binding protein RhoH chr4 Census Yes 1 hippie 41 12 3 3 0
RHOU RHOU Q7L0Q8 Rho-related GTP-binding protein RhoU chr1 Not Cancer Driver No 1 hippie 34 63 6 6 0
RND2 RND2 P52198 Rho-related GTP-binding protein RhoN chr17 Not Cancer Driver No 1 hippie 19 54 4 4 0
RPGRIP1L_ENST00000379925 RPGRIP1L Q68CZ1 Protein fantom chr16 Not Cancer Driver No 1 intact, hippie 177 586 94 94 8
RPUSD3 RPUSD3 Q6P087 Mitochondrial mRNA pseudouridine synthase RPUSD3 chr3 Not Cancer Driver No 1 hippie, biogrid 33 85 5 5 0
RPUSD4 RPUSD4 Q96CM3 Pseudouridylate synthase RPUSD4, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 54 97 15 15 0
SIRT4 SIRT4 Q9Y6E7 NAD-dependent protein lipoamidase sirtuin-4, mitochondrial chr12 Not Cancer Driver No 1 hippie 46 4 0 0 0
SLFN11_ENST00000308377 SLFN11 Q7Z7L1 Schlafen family member 11 chr17 Not Cancer Driver No 1 hippie 177 34 8 8 0
SLIRP SLIRP Q9GZT3 SRA stem-loop-interacting RNA-binding protein, mitochondrial chr14 Not Cancer Driver No 2 hippie, biogrid 7 41 3 3 0
SNRNP70 SNRNP70 P08621 U1 small nuclear ribonucleoprotein 70 kDa chr19 Not Cancer Driver No 1 hippie 38 416 37 37 0
SP100_ENST00000264052 SP100 P23497 Nuclear autoantigen Sp-100 chr2 Not Cancer Driver No 1 hippie 136 680 101 101 0
SPATA20_ENST00000356488 SPATA20 Q8TB22 Spermatogenesis-associated protein 20 chr17 Not Cancer Driver No 1 hippie 101 162 19 19 0
SPRTN SPRTN Q9H040 DNA-dependent metalloprotease SPRTN chr1 Not Cancer Driver No 1 hippie 73 252 38 38 1
SRRM2 SRRM2 Q9UQ35 Serine/arginine repetitive matrix protein 2 chr16 Not Cancer Driver No 1 hippie 433 2748 431 431 0
SSBP1_ENST00000484178 SSBP1 Q04837 Single-stranded DNA-binding protein, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 27 0 0 0 6
STK24 STK24 Q9Y6E0 Serine/threonine-protein kinase 24 chr13 Not Cancer Driver No 1 hippie 67 118 16 16 0
SURF6 SURF6 O75683 Surfeit locus protein 6 chr9 Not Cancer Driver No 1 hippie, biogrid 58 337 56 56 0
TACO1 TACO1 Q9BSH4 Translational activator of cytochrome c oxidase 1 chr17 Not Cancer Driver No 1 hippie, biogrid 21 111 2 2 0
TAL1 TAL1 P17542 T-cell acute lymphocytic leukemia protein 1 chr1 Census Yes 1 intact, hippie 54 305 53 53 0
TBRG4_ENST00000494076 TBRG4 Q969Z0 FAST kinase domain-containing protein 4 chr7 Not Cancer Driver No 1 hippie, biogrid 74 60 2 2 0
TFAM TFAM Q00059 Transcription factor A, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 25 110 15 15 1
THEM4 THEM4 Q5T1C6 Acyl-coenzyme A thioesterase THEM4 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 19 14 0 0 0
TNFRSF1B TNFRSF1B P20333 Tumor necrosis factor receptor superfamily member 1B chr1 Not Cancer Driver No 2 intact, hippie, biogrid 48 229 28 28 0
TRAP1 TRAP1 Q12931 Heat shock protein 75 kDa, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 74 110 11 11 0
TRIM33 TRIM33 Q9UPN9 E3 ubiquitin-protein ligase TRIM33 chr1 Census, Compendium Yes 1 hippie 110 617 51 51 0
TRIP4 TRIP4 Q15650 Activating signal cointegrator 1 chr15 Not Cancer Driver No 1 hippie 71 176 27 27 0
TRMT61B TRMT61B Q9BVS5 tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial chr2 Not Cancer Driver No 2 intact, hippie, biogrid 48 123 10 10 0
TRUB2 TRUB2 O95900 Pseudouridylate synthase TRUB2, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 37 73 7 7 0
TSFM_ENST00000454289 TSFM P43897 Elongation factor Ts, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 37 74 7 7 2
TUFM TUFM P49411 Elongation factor Tu, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 51 50 3 3 1
USP16 USP16 Q9Y5T5 Ubiquitin carboxyl-terminal hydrolase 16 chr21 Not Cancer Driver No 1 intact, hippie, biogrid 98 394 42 42 0
YBX1 YBX1 P67809 Y-box-binding protein 1 chr1 Not Cancer Driver No 1 intact, hippie 41 312 41 41 0
ZADH2 PTGR3 Q8N4Q0 Prostaglandin reductase 3 chr18 Not Cancer Driver No 1 intact 42 0 0 0 0