Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AARS2 | AARS2 | Q5JTZ9 | Alanine--tRNA ligase, mitochondrial | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 123 | 203 | 25 | 25 | 5 |
| ABCC1 | ABCC1 | P33527 | Multidrug resistance-associated protein 1 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 199 | 123 | 22 | 22 | 1 |
| ACAA2 | ACAA2 | P42765 | 3-ketoacyl-CoA thiolase, mitochondrial | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 42 | 51 | 2 | 2 | 0 |
| ACAD9 | ACAD9 | Q9H845 | Complex I assembly factor ACAD9, mitochondrial | chr3 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 69 | 28 | 5 | 5 | 12 |
| ACOT13 | ACOT13 | Q9NPJ3 | Acyl-coenzyme A thioesterase 13 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 23 | 2 | 2 | 0 |
| ADI1 | ADI1 | Q9BV57 | Acireductone dioxygenase | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 23 | 1 | 1 | 0 |
| AGMAT | AGMAT | Q9BSE5 | Agmatinase, mitochondrial | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 53 | 106 | 10 | 10 | 0 |
| AGO3 | AGO3 | Q9H9G7 | Protein argonaute-3 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 110 | 143 | 19 | 19 | 0 |
| AGO4 | AGO4 | Q9HCK5 | Protein argonaute-4 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 100 | 183 | 24 | 24 | 0 |
| AIFM1 | AIFM1 | O95831 | Apoptosis-inducing factor 1, mitochondrial | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 88 | 166 | 22 | 22 | 11 |
| AIMP2 | AIMP2 | Q13155 | Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 | chr7 | Not Cancer Driver | No | 1 | hippie | 46 | 61 | 8 | 8 | 0 |
| ALDOA_ENST00000643777 | ALDOA | P04075 | Fructose-bisphosphate aldolase A | chr16 | Not Cancer Driver | No | 1 | intact | 47 | 65 | 9 | 9 | 3 |
| ATG16L1 | ATG16L1 | Q676U5 | Autophagy-related protein 16-1 | chr2 | Not Cancer Driver | No | 1 | hippie | 79 | 239 | 25 | 25 | 1 |
| ATXN3 | ATXN3 | P54252 | Ataxin-3 | chr14 | Not Cancer Driver | No | 1 | hippie | 46 | 181 | 24 | 24 | 0 |
| AUH | AUH | Q13825 | Methylglutaconyl-CoA hydratase, mitochondrial | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 29 | 0 | 0 | 1 |
| BCKDHB | BCKDHB | P21953 | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | chr6 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 47 | 23 | 3 | 3 | 5 |
| BICD1 | BICD1 | Q96G01 | Protein bicaudal D homolog 1 | chr12 | Not Cancer Driver | No | 1 | hippie | 124 | 656 | 86 | 86 | 0 |
| BIRC3_ENST00000532808 | BIRC3 | Q13489 | Baculoviral IAP repeat-containing protein 3 | chr11 | Census, Compendium | Yes | 1 | hippie | 77 | 98 | 16 | 16 | 0 |
| BMI1 | BMI1 | P35226 | Polycomb complex protein BMI-1 | chr10 | Not Cancer Driver | No | 1 | intact, hippie | 50 | 150 | 30 | 30 | 0 |
| BRD1_ENST00000216267 | BRD1 | O95696 | Bromodomain-containing protein 1 | chr22 | Not Cancer Driver | No | 1 | hippie | 171 | 425 | 68 | 68 | 0 |
| BRD7_ENST00000394688 | BRD7 | Q9NPI1 | Bromodomain-containing protein 7 | chr16 | Compendium | Yes | 1 | hippie | 82 | 482 | 57 | 57 | 0 |
| BRPF3 | BRPF3 | Q9ULD4 | Bromodomain and PHD finger-containing protein 3 | chr6 | Not Cancer Driver | No | 1 | hippie | 143 | 633 | 74 | 74 | 0 |
| C17orf80_ENST00000535032 | C17orf80 | Q9BSJ5 | Uncharacterized protein C17orf80 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 64 | 455 | 53 | 53 | 0 |
| CA5B_ENST00000454127 | CA5B | Q9Y2D0 | Carbonic anhydrase 5B, mitochondrial | chrX | Not Cancer Driver | No | 2 | hippie, biogrid | 40 | 28 | 2 | 2 | 0 |
| CCDC90B | CCDC90B | Q9GZT6 | Coiled-coil domain-containing protein 90B, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 76 | 6 | 6 | 0 |
| CDO1 | CDO1 | Q16878 | Cysteine dioxygenase type 1 | chr5 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 37 | 43 | 4 | 4 | 0 |
| CECR2_ENST00000342247 | CECR2 | Q9BXF3 | Cat eye syndrome critical region protein 2 | chr22 | Not Cancer Driver | No | 1 | hippie | 222 | 1192 | 183 | 183 | 0 |
| CEP128_ENST00000281129 | CEP128 | Q6ZU80 | Centrosomal protein of 128 kDa | chr14 | Not Cancer Driver | No | 1 | hippie | 195 | 897 | 167 | 167 | 0 |
| CEP152 | CEP152 | O94986 | Centrosomal protein of 152 kDa | chr15 | Not Cancer Driver | No | 1 | intact, hippie | 204 | 986 | 110 | 110 | 2 |
| CEP164 | CEP164 | Q9UPV0 | Centrosomal protein of 164 kDa | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 161 | 1198 | 124 | 124 | 2 |
| CHCHD2 | CHCHD2 | Q9Y6H1 | Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 | chr7 | Not Cancer Driver | No | 1 | intact, hippie | 24 | 114 | 21 | 21 | 1 |
| CNTRL_ENST00000238341 | CNTRL | Q7Z7A1 | Centriolin | chr9 | Census | Yes | 1 | hippie | 234 | 1556 | 159 | 159 | 0 |
| COQ8A | COQ8A | Q8NI60 | Atypical kinase COQ8A, mitochondrial | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 95 | 166 | 29 | 29 | 12 |
| COX4I1 | COX4I1 | P13073 | Cytochrome c oxidase subunit 4 isoform 1, mitochondrial | chr16 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 17 | 5 | 1 | 1 | 1 |
| COX5B | COX5B | P10606 | Cytochrome c oxidase subunit 5B, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 58 | 6 | 6 | 0 |
| COX8A | COX8A | P10176 | Cytochrome c oxidase subunit 8A, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 10 | 1 | 0 | 0 | 0 |
| CS | CS | O75390 | Citrate synthase, mitochondrial | chr12 | Not Cancer Driver | No | 2 | hippie, biogrid | 50 | 13 | 2 | 2 | 0 |
| CSK_ENST00000439220 | CSK | P41240 | Tyrosine-protein kinase CSK | chr15 | Not Cancer Driver | No | 1 | hippie | 41 | 18 | 1 | 1 | 0 |
| CSNK1A1_ENST00000377843 | CSNK1A1 | P48729 | Casein kinase I isoform alpha | chr5 | Not Cancer Driver | No | 1 | hippie | 44 | 46 | 3 | 3 | 0 |
| DCAF11 | DCAF11 | Q8TEB1 | DDB1- and CUL4-associated factor 11 | chr14 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 89 | 149 | 25 | 25 | 0 |
| DCAF15 | DCAF15 | Q66K64 | DDB1- and CUL4-associated factor 15 | chr19 | Not Cancer Driver | No | 1 | hippie | 50 | 173 | 18 | 18 | 0 |
| DDX1 | DDX1 | Q92499 | ATP-dependent RNA helicase DDX1 | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 82 | 91 | 15 | 15 | 0 |
| DDX58 | DDX58 | O95786 | Antiviral innate immune response receptor RIG-I | chr9 | Not Cancer Driver | No | 1 | hippie | 118 | 61 | 10 | 10 | 2 |
| DLD | DLD | P09622 | Dihydrolipoyl dehydrogenase, mitochondrial | chr7 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 67 | 17 | 0 | 0 | 10 |
| DLST | DLST | P36957 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 53 | 190 | 32 | 32 | 1 |
| DNAJB13 | DNAJB13 | P59910 | DnaJ homolog subfamily B member 13 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 57 | 42 | 14 | 14 | 1 |
| DNM1L_ENST00000549701 | DNM1L | O00429 | Dynamin-1-like protein | chr12 | Not Cancer Driver | No | 1 | hippie | 67 | 212 | 23 | 23 | 7 |
| DPF2_ENST00000528416 | DPF2 | Q92785 | Zinc finger protein ubi-d4 | chr11 | Not Cancer Driver | No | 1 | hippie | 67 | 179 | 30 | 30 | 5 |
| DYNC1I1 | DYNC1I1 | O14576 | Cytoplasmic dynein 1 intermediate chain 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 146 | 255 | 60 | 60 | 0 |
| DYNLRB1 | DYNLRB1 | Q9NP97 | Dynein light chain roadblock-type 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 23 | 19 | 4 | 4 | 0 |
| DYNLT1 | DYNLT1 | P63172 | Dynein light chain Tctex-type 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 7 | 1 | 0 | 0 | 0 |
| ECH1 | ECH1 | Q13011 | Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 35 | 23 | 2 | 2 | 0 |
| ECHDC2 | ECHDC2 | Q86YB7 | Enoyl-CoA hydratase domain-containing protein 2, mitochondrial | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 10 | 1 | 1 | 0 |
| ECHS1 | ECHS1 | P30084 | Enoyl-CoA hydratase, mitochondrial | chr10 | Not Cancer Driver | No | 3 | hippie, biogrid | 51 | 7 | 1 | 1 | 14 |
| EMC2 | EMC2 | Q15006 | ER membrane protein complex subunit 2 | chr8 | Not Cancer Driver | No | 1 | hippie | 48 | 29 | 3 | 3 | 0 |
| EPB41L5 | EPB41L5 | Q9HCM4 | Band 4.1-like protein 5 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 97 | 312 | 45 | 45 | 0 |
| ESR2 | ESR2 | Q92731 | Estrogen receptor beta | chr14 | Not Cancer Driver | No | 1 | hippie | 90 | 92 | 11 | 11 | 1 |
| EXD2 | EXD2 | Q9NVH0 | Exonuclease 3'-5' domain-containing protein 2 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 176 | 15 | 15 | 0 |
| FAHD1_ENST00000427358 | FAHD1 | Q6P587 | Acylpyruvase FAHD1, mitochondrial | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 12 | 0 | 0 | 0 |
| FAHD2A | FAHD2A | Q96GK7 | Fumarylacetoacetate hydrolase domain-containing protein 2A | chr2 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 39 | 8 | 2 | 2 | 0 |
| FAHD2B | FAHD2B | Q6P2I3 | Fumarylacetoacetate hydrolase domain-containing protein 2B | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 44 | 4 | 3 | 3 | 0 |
| FAM133A_ENST00000332647 | FAM133A | Q8N9E0 | Protein FAM133A | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 59 | 248 | 59 | 59 | 0 |
| FAM136A | FAM136A | Q96C01 | Protein FAM136A | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 17 | 13 | 1 | 1 | 0 |
| FAM160A2_ENST00000449352 | FHIP1B | Q8N612 | FHF complex subunit HOOK interacting protein 1B | chr11 | Not Cancer Driver | No | 1 | intact | 129 | 415 | 54 | 54 | 0 |
| FAM160B1 | FHIP2A | Q5W0V3 | FHF complex subunit HOOK interacting protein 2A | chr10 | Not Cancer Driver | No | 1 | intact | 92 | 130 | 13 | 13 | 0 |
| FAM160B2 | FHIP2B | Q86V87 | FHF complex subunit HOOK interacting protein 2B | chr8 | Not Cancer Driver | No | 1 | intact | 75 | 139 | 14 | 14 | 0 |
| FASTKD3 | FASTKD3 | Q14CZ7 | FAST kinase domain-containing protein 3, mitochondrial | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 106 | 6 | 1 | 1 | 0 |
| FASTKD5 | FASTKD5 | Q7L8L6 | FAST kinase domain-containing protein 5, mitochondrial | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 86 | 94 | 8 | 8 | 0 |
| FH | FH | P07954 | Fumarate hydratase, mitochondrial | chr1 | Census, Compendium | Yes | 1 | hippie, biogrid | 67 | 76 | 5 | 5 | 13 |
| FOXQ1 | FOXQ1 | Q9C009 | Forkhead box protein Q1 | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 22 | 245 | 4 | 4 | 0 |
| GATM | GATM | P50440 | Glycine amidinotransferase, mitochondrial | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 69 | 33 | 8 | 8 | 15 |
| GBF1 | GBF1 | Q92538 | Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 | chr10 | Not Cancer Driver | No | 1 | hippie | 216 | 669 | 76 | 76 | 0 |
| GFM1_ENST00000486715 | GFM1 | Q96RP9 | Elongation factor G, mitochondrial | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 74 | 79 | 7 | 7 | 4 |
| GFM2_ENST00000509430 | GFM2 | Q969S9 | Ribosome-releasing factor 2, mitochondrial | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 75 | 100 | 10 | 10 | 2 |
| GRPEL2 | GRPEL2 | Q8TAA5 | GrpE protein homolog 2, mitochondrial | chr5 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 17 | 45 | 3 | 3 | 0 |
| GRSF1 | GRSF1 | Q12849 | G-rich sequence factor 1 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 49 | 147 | 20 | 20 | 0 |
| HDAC6_ENST00000426196 | HDAC6 | Q9UBN7 | Histone deacetylase 6 | chrX | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 178 | 409 | 59 | 59 | 0 |
| HECTD1 | HECTD1 | Q9ULT8 | E3 ubiquitin-protein ligase HECTD1 | chr14 | Not Cancer Driver | No | 1 | hippie | 274 | 991 | 108 | 108 | 0 |
| HINT2 | HINT2 | Q9BX68 | Adenosine 5'-monophosphoramidase HINT2 | chr9 | Not Cancer Driver | No | 2 | hippie, biogrid | 10 | 29 | 2 | 2 | 0 |
| HMGCL | HMGCL | P35914 | Hydroxymethylglutaryl-CoA lyase, mitochondrial | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 17 | 8 | 2 | 2 | 19 |
| HNRNPU | HNRNPU | Q00839 | Heterogeneous nuclear ribonucleoprotein U | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 77 | 504 | 45 | 45 | 0 |
| HOGA1 | HOGA1 | Q86XE5 | 4-hydroxy-2-oxoglutarate aldolase, mitochondrial | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 2 | 0 | 0 | 2 |
| HOOK1 | HOOK1 | Q9UJC3 | Protein Hook homolog 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 97 | 427 | 59 | 59 | 0 |
| HSD17B10 | HSD17B10 | Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 15 | 3 | 3 | 11 |
| HUWE1_ENST00000262854 | HUWE1 | Q7Z6Z7 | E3 ubiquitin-protein ligase HUWE1 | chrX | Not Cancer Driver | No | 1 | hippie | 669 | 2091 | 329 | 329 | 21 |
| IDH3B_ENST00000380843 | IDH3B | O43837 | Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial | chr20 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 32 | 49 | 3 | 3 | 1 |
| IFIT2_ENST00000371826 | IFIT2 | P09913 | Interferon-induced protein with tetratricopeptide repeats 2 | chr10 | Not Cancer Driver | No | 1 | intact, hippie | 73 | 85 | 17 | 17 | 0 |
| ISCA2 | ISCA2 | Q86U28 | Iron-sulfur cluster assembly 2 homolog, mitochondrial | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 13 | 38 | 3 | 3 | 1 |
| JUN | JUN | P05412 | Transcription factor Jun | chr1 | Census | Yes | 1 | hippie | 35 | 281 | 25 | 25 | 0 |
| LACTB | LACTB | P83111 | Serine beta-lactamase-like protein LACTB, mitochondrial | chr15 | Not Cancer Driver | No | 1 | intact, hippie | 44 | 121 | 3 | 3 | 0 |
| LIPT1 | LIPT1 | Q9Y234 | Lipoyltransferase 1, mitochondrial | chr2 | Not Cancer Driver | No | 3 | hippie, biogrid | 34 | 0 | 0 | 0 | 3 |
| LRPPRC | LRPPRC | P42704 | Leucine-rich PPR motif-containing protein, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 131 | 18 | 2 | 2 | 1 |
| LYRM4_ENST00000330636 | LYRM4 | Q9HD34 | LYR motif-containing protein 4 | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 14 | 11 | 1 | 1 | 1 |
| MCAT | MCAT | Q8IVS2 | Malonyl-CoA-acyl carrier protein transacylase, mitochondrial | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 38 | 52 | 2 | 2 | 0 |
| MCEE | MCEE | Q96PE7 | Methylmalonyl-CoA epimerase, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 19 | 9 | 0 | 0 | 0 |
| MCUB | MCUB | Q9NWR8 | Calcium uniporter regulatory subunit MCUb, mitochondrial | chr4 | Not Cancer Driver | No | 1 | hippie | 33 | 24 | 1 | 1 | 0 |
| MDH2 | MDH2 | P40926 | Malate dehydrogenase, mitochondrial | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 39 | 8 | 1 | 1 | 3 |
| MECR | MECR | Q9BV79 | Enoyl-[acyl-carrier-protein] reductase, mitochondrial | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 55 | 26 | 5 | 5 | 3 |
| MED4 | MED4 | Q9NPJ6 | Mediator of RNA polymerase II transcription subunit 4 | chr13 | Not Cancer Driver | No | 1 | hippie | 29 | 161 | 17 | 17 | 0 |
| METTL15 | METTL15 | A6NJ78 | 12S rRNA N4-methylcytidine (m4C) methyltransferase | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 46 | 92 | 14 | 14 | 0 |
| METTL17_ENST00000339374 | METTL17 | Q9H7H0 | Methyltransferase-like protein 17, mitochondrial | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 62 | 95 | 16 | 16 | 0 |
| MICU3 | MICU3 | Q86XE3 | Calcium uptake protein 3, mitochondrial | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 72 | 89 | 8 | 8 | 0 |
| MKS1 | MKS1 | Q9NXB0 | Meckel syndrome type 1 protein | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 82 | 152 | 23 | 23 | 2 |
| MMAB | MMAB | Q96EY8 | Corrinoid adenosyltransferase MMAB | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 36 | 68 | 14 | 14 | 5 |
| MRPL11 | MRPL11 | Q9Y3B7 | 39S ribosomal protein L11, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 12 | 1 | 1 | 0 |
| MRPL18 | MRPL18 | Q9H0U6 | 39S ribosomal protein L18, mitochondrial | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 35 | 2 | 2 | 0 |
| MRPL53 | MRPL53 | Q96EL3 | 39S ribosomal protein L53, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 22 | 1 | 1 | 0 |
| MRPL58 | MRPL58 | Q14197 | Peptidyl-tRNA hydrolase ICT1, mitochondrial | chr17 | Not Cancer Driver | No | 1 | hippie | 28 | 105 | 13 | 13 | 0 |
| MRPS11 | MRPS11 | P82912 | 28S ribosomal protein S11, mitochondrial | chr15 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 23 | 114 | 12 | 12 | 0 |
| MRPS18C | MRPS18C | Q9Y3D5 | 28S ribosomal protein S18c, mitochondrial | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 5 | 1 | 1 | 0 |
| MRPS26 | MRPS26 | Q9BYN8 | 28S ribosomal protein S26, mitochondrial | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 102 | 6 | 6 | 0 |
| MRPS36 | MRPS36 | P82909 | Alpha-ketoglutarate dehydrogenase component 4 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 12 | 103 | 12 | 12 | 0 |
| MRPS6 | MRPS6 | P82932 | 28S ribosomal protein S6, mitochondrial | chr21 | Not Cancer Driver | No | 1 | hippie, biogrid | 17 | 13 | 1 | 1 | 0 |
| MRRF | MRRF | Q96E11 | Ribosome-recycling factor, mitochondrial | chr9 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 23 | 118 | 9 | 9 | 0 |
| MSRB2 | MSRB2 | Q9Y3D2 | Methionine-R-sulfoxide reductase B2, mitochondrial | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 17 | 65 | 6 | 6 | 0 |
| MTERF3 | MTERF3 | Q96E29 | Transcription termination factor 3, mitochondrial | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 53 | 62 | 5 | 5 | 0 |
| MTG2 | MTG2 | Q9H4K7 | Mitochondrial ribosome-associated GTPase 2 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 57 | 47 | 9 | 9 | 0 |
| MTIF2_ENST00000403721 | MTIF2 | P46199 | Translation initiation factor IF-2, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 101 | 112 | 9 | 9 | 0 |
| MTIF3_ENST00000381120 | MTIF3 | Q9H2K0 | Translation initiation factor IF-3, mitochondrial | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 180 | 19 | 19 | 0 |
| MTRF1 | MTRF1 | O75570 | Peptide chain release factor 1, mitochondrial | chr13 | Not Cancer Driver | No | 2 | hippie, biogrid | 50 | 71 | 9 | 9 | 0 |
| MTRF1L | MTRF1L | Q9UGC7 | Peptide chain release factor 1-like, mitochondrial | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 183 | 12 | 12 | 0 |
| MYO6 | MYO6 | Q9UM54 | Unconventional myosin-VI | chr6 | Not Cancer Driver | No | 1 | hippie | 176 | 342 | 41 | 41 | 3 |
| NABP1 | NABP1 | Q96AH0 | SOSS complex subunit B2 | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 25 | 102 | 11 | 11 | 0 |
| NABP2_ENST00000341463 | NABP2 | Q9BQ15 | SOSS complex subunit B1 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 25 | 125 | 17 | 17 | 0 |
| NCAPD3 | NCAPD3 | P42695 | Condensin-2 complex subunit D3 | chr11 | Not Cancer Driver | No | 1 | hippie | 193 | 304 | 42 | 42 | 1 |
| NDUFS6 | NDUFS6 | O75380 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 8 | 0 | 0 | 1 |
| NF2 | NF2 | P35240 | Merlin | chr22 | Census, Compendium | Yes | 1 | hippie | 69 | 252 | 26 | 26 | 16 |
| NFKB1_ENST00000505458 | NFKB1 | P19838 | Nuclear factor NF-kappa-B p105 subunit | chr4 | Not Cancer Driver | No | 1 | intact, hippie | 104 | 344 | 38 | 38 | 0 |
| NIN | NIN | Q8N4C6 | Ninein | chr14 | Census, Compendium | Yes | 1 | hippie | 239 | 1392 | 164 | 164 | 2 |
| NIPSNAP3B | NIPSNAP3B | Q9BS92 | Protein NipSnap homolog 3B | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 15 | 1 | 1 | 0 |
| NOCT | NOCT | Q9UK39 | Nocturnin | chr4 | Not Cancer Driver | No | 1 | intact, hippie | 33 | 89 | 3 | 3 | 0 |
| NPHP1_ENST00000393272 | NPHP1 | O15259 | Nephrocystin-1 | chr2 | Not Cancer Driver | No | 1 | hippie | 108 | 259 | 32 | 32 | 1 |
| NR2C2_ENST00000393102 | NR2C2 | P49116 | Nuclear receptor subfamily 2 group C member 2 | chr3 | Not Cancer Driver | No | 1 | hippie | 62 | 186 | 24 | 24 | 0 |
| NR3C1_ENST00000343796 | NR3C1 | P04150 | Glucocorticoid receptor | chr5 | Not Cancer Driver | No | 1 | hippie | 92 | 362 | 37 | 37 | 12 |
| NUDT6 | NUDT6 | P53370 | Nucleoside diphosphate-linked moiety X motif 6 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 40 | 14 | 0 | 0 | 0 |
| OGT | OGT | O15294 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | chrX | Not Cancer Driver | No | 1 | hippie | 156 | 89 | 16 | 16 | 2 |
| OXLD1 | OXLD1 | Q5BKU9 | Oxidoreductase-like domain-containing protein 1 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 84 | 17 | 17 | 0 |
| PCBD2_ENST00000254908 | PCBD2 | Q9H0N5 | Pterin-4-alpha-carbinolamine dehydratase 2 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 6 | 3 | 0 | 0 | 0 |
| PDHA1_ENST00000422285 | PDHA1 | P08559 | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 70 | 43 | 6 | 6 | 20 |
| PDP1_ENST00000297598 | PDP1 | Q9P0J1 | [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 64 | 96 | 9 | 9 | 0 |
| PGR | PGR | P06401 | Progesterone receptor | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 161 | 480 | 55 | 55 | 0 |
| PHIP | PHIP | Q8WWQ0 | PH-interacting protein | chr6 | Not Cancer Driver | No | 1 | hippie | 239 | 835 | 110 | 110 | 0 |
| PHYHIPL | PHYHIPL | Q96FC7 | Phytanoyl-CoA hydroxylase-interacting protein-like | chr10 | Not Cancer Driver | No | 1 | intact, hippie | 49 | 68 | 9 | 9 | 0 |
| PMPCA | PMPCA | Q10713 | Mitochondrial-processing peptidase subunit alpha | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 23 | 3 | 3 | 4 |
| PMPCB | PMPCB | O75439 | Mitochondrial-processing peptidase subunit beta | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 55 | 22 | 3 | 3 | 5 |
| PPM1K | PPM1K | Q8N3J5 | Protein phosphatase 1K, mitochondrial | chr4 | Not Cancer Driver | No | 5 | intact, hippie, biogrid | 59 | 62 | 12 | 12 | 0 |
| PPP6C_ENST00000373547 | PPP6C | O00743 | Serine/threonine-protein phosphatase 6 catalytic subunit | chr9 | Census, Compendium | Yes | 1 | intact, hippie | 63 | 0 | 0 | 0 | 0 |
| PPT1 | PPT1 | P50897 | Palmitoyl-protein thioesterase 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 37 | 0 | 0 | 0 | 23 |
| PPTC7 | PPTC7 | Q8NI37 | Protein phosphatase PTC7 homolog | chr12 | Not Cancer Driver | No | 2 | hippie, biogrid | 32 | 36 | 2 | 2 | 0 |
| PRDM4 | PRDM4 | Q9UKN5 | PR domain zinc finger protein 4 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 92 | 362 | 40 | 40 | 0 |
| PRKAA1_ENST00000397128 | PRKAA1 | Q13131 | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | chr5 | Not Cancer Driver | No | 1 | hippie | 72 | 124 | 17 | 17 | 0 |
| PRKD2_ENST00000291281 | PRKD2 | Q9BZL6 | Serine/threonine-protein kinase D2 | chr19 | Compendium | Yes | 1 | hippie | 118 | 246 | 34 | 34 | 0 |
| PRKN | PRKN | O60260 | E3 ubiquitin-protein ligase parkin | chr6 | Not Cancer Driver | No | 1 | hippie | 110 | 78 | 15 | 15 | 31 |
| PRSS35 | PRSS35 | Q8N3Z0 | Inactive serine protease 35 | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 97 | 115 | 29 | 29 | 0 |
| PTEN | PTEN | P60484 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | chr10 | Census, Compendium | Yes | 1 | hippie | 505 | 76 | 4 | 4 | 41 |
| RAB17 | RAB17 | Q9H0T7 | Ras-related protein Rab-17 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 29 | 43 | 4 | 4 | 0 |
| RALB | RALB | P11234 | Ras-related protein Ral-B | chr2 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 36 | 35 | 5 | 5 | 0 |
| RBM5 | RBM5 | P52756 | RNA-binding protein 5 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 94 | 537 | 67 | 67 | 0 |
| RECQL4 | RECQL4 | O94761 | ATP-dependent DNA helicase Q4 | chr8 | Census, Compendium | Yes | 1 | hippie | 138 | 608 | 71 | 71 | 1 |
| RHOG_ENST00000396978 | RHOG | P84095 | Rho-related GTP-binding protein RhoG | chr11 | Not Cancer Driver | No | 1 | hippie | 26 | 22 | 5 | 5 | 0 |
| RHOH_ENST00000617441 | RHOH | Q15669 | Rho-related GTP-binding protein RhoH | chr4 | Census | Yes | 1 | hippie | 41 | 12 | 3 | 3 | 0 |
| RHOU | RHOU | Q7L0Q8 | Rho-related GTP-binding protein RhoU | chr1 | Not Cancer Driver | No | 1 | hippie | 34 | 63 | 6 | 6 | 0 |
| RND2 | RND2 | P52198 | Rho-related GTP-binding protein RhoN | chr17 | Not Cancer Driver | No | 1 | hippie | 19 | 54 | 4 | 4 | 0 |
| RPGRIP1L_ENST00000379925 | RPGRIP1L | Q68CZ1 | Protein fantom | chr16 | Not Cancer Driver | No | 1 | intact, hippie | 177 | 586 | 94 | 94 | 8 |
| RPUSD3 | RPUSD3 | Q6P087 | Mitochondrial mRNA pseudouridine synthase RPUSD3 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 33 | 85 | 5 | 5 | 0 |
| RPUSD4 | RPUSD4 | Q96CM3 | Pseudouridylate synthase RPUSD4, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 54 | 97 | 15 | 15 | 0 |
| SIRT4 | SIRT4 | Q9Y6E7 | NAD-dependent protein lipoamidase sirtuin-4, mitochondrial | chr12 | Not Cancer Driver | No | 1 | hippie | 46 | 4 | 0 | 0 | 0 |
| SLFN11_ENST00000308377 | SLFN11 | Q7Z7L1 | Schlafen family member 11 | chr17 | Not Cancer Driver | No | 1 | hippie | 177 | 34 | 8 | 8 | 0 |
| SLIRP | SLIRP | Q9GZT3 | SRA stem-loop-interacting RNA-binding protein, mitochondrial | chr14 | Not Cancer Driver | No | 2 | hippie, biogrid | 7 | 41 | 3 | 3 | 0 |
| SNRNP70 | SNRNP70 | P08621 | U1 small nuclear ribonucleoprotein 70 kDa | chr19 | Not Cancer Driver | No | 1 | hippie | 38 | 416 | 37 | 37 | 0 |
| SP100_ENST00000264052 | SP100 | P23497 | Nuclear autoantigen Sp-100 | chr2 | Not Cancer Driver | No | 1 | hippie | 136 | 680 | 101 | 101 | 0 |
| SPATA20_ENST00000356488 | SPATA20 | Q8TB22 | Spermatogenesis-associated protein 20 | chr17 | Not Cancer Driver | No | 1 | hippie | 101 | 162 | 19 | 19 | 0 |
| SPRTN | SPRTN | Q9H040 | DNA-dependent metalloprotease SPRTN | chr1 | Not Cancer Driver | No | 1 | hippie | 73 | 252 | 38 | 38 | 1 |
| SRRM2 | SRRM2 | Q9UQ35 | Serine/arginine repetitive matrix protein 2 | chr16 | Not Cancer Driver | No | 1 | hippie | 433 | 2748 | 431 | 431 | 0 |
| SSBP1_ENST00000484178 | SSBP1 | Q04837 | Single-stranded DNA-binding protein, mitochondrial | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 0 | 0 | 0 | 6 |
| STK24 | STK24 | Q9Y6E0 | Serine/threonine-protein kinase 24 | chr13 | Not Cancer Driver | No | 1 | hippie | 67 | 118 | 16 | 16 | 0 |
| SURF6 | SURF6 | O75683 | Surfeit locus protein 6 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 337 | 56 | 56 | 0 |
| TACO1 | TACO1 | Q9BSH4 | Translational activator of cytochrome c oxidase 1 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 21 | 111 | 2 | 2 | 0 |
| TAL1 | TAL1 | P17542 | T-cell acute lymphocytic leukemia protein 1 | chr1 | Census | Yes | 1 | intact, hippie | 54 | 305 | 53 | 53 | 0 |
| TBRG4_ENST00000494076 | TBRG4 | Q969Z0 | FAST kinase domain-containing protein 4 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 74 | 60 | 2 | 2 | 0 |
| TFAM | TFAM | Q00059 | Transcription factor A, mitochondrial | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 110 | 15 | 15 | 1 |
| THEM4 | THEM4 | Q5T1C6 | Acyl-coenzyme A thioesterase THEM4 | chr1 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 19 | 14 | 0 | 0 | 0 |
| TNFRSF1B | TNFRSF1B | P20333 | Tumor necrosis factor receptor superfamily member 1B | chr1 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 48 | 229 | 28 | 28 | 0 |
| TRAP1 | TRAP1 | Q12931 | Heat shock protein 75 kDa, mitochondrial | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 74 | 110 | 11 | 11 | 0 |
| TRIM33 | TRIM33 | Q9UPN9 | E3 ubiquitin-protein ligase TRIM33 | chr1 | Census, Compendium | Yes | 1 | hippie | 110 | 617 | 51 | 51 | 0 |
| TRIP4 | TRIP4 | Q15650 | Activating signal cointegrator 1 | chr15 | Not Cancer Driver | No | 1 | hippie | 71 | 176 | 27 | 27 | 0 |
| TRMT61B | TRMT61B | Q9BVS5 | tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial | chr2 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 48 | 123 | 10 | 10 | 0 |
| TRUB2 | TRUB2 | O95900 | Pseudouridylate synthase TRUB2, mitochondrial | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 73 | 7 | 7 | 0 |
| TSFM_ENST00000454289 | TSFM | P43897 | Elongation factor Ts, mitochondrial | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 74 | 7 | 7 | 2 |
| TUFM | TUFM | P49411 | Elongation factor Tu, mitochondrial | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 50 | 3 | 3 | 1 |
| USP16 | USP16 | Q9Y5T5 | Ubiquitin carboxyl-terminal hydrolase 16 | chr21 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 98 | 394 | 42 | 42 | 0 |
| YBX1 | YBX1 | P67809 | Y-box-binding protein 1 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 41 | 312 | 41 | 41 | 0 |
| ZADH2 | PTGR3 | Q8N4Q0 | Prostaglandin reductase 3 | chr18 | Not Cancer Driver | No | 1 | intact | 42 | 0 | 0 | 0 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|