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DARS2 ,DARS2 ,Q6PI48
  • Uniprot Accession= Q6PI48
  • Ensembl Transcript= ENST00000361951.4
  • Uniprot Name= DARS2
  • Name= Aspartate--tRNA ligase, mitochondrial
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 59
  • Number of Interaction partner in hippie: 110
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
AARS2 AARS2 Q5JTZ9 Alanine--tRNA ligase, mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 123 203 25 25 5
ABHD10 ABHD10 Q9NUJ1 Palmitoyl-protein thioesterase ABHD10, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 38 7 2 2 0
ACAA2 ACAA2 P42765 3-ketoacyl-CoA thiolase, mitochondrial chr18 Not Cancer Driver No 1 hippie, biogrid 42 51 2 2 0
ACBD3 ACBD3 Q9H3P7 Golgi resident protein GCP60 chr1 Not Cancer Driver No 1 hippie 59 350 40 40 0
ACSM5 ACSM5 Q6NUN0 Acyl-coenzyme A synthetase ACSM5, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 152 84 27 27 0
AIFM1 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX Not Cancer Driver No 3 hippie, biogrid 88 166 22 22 11
AIMP2 AIMP2 Q13155 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 chr7 Not Cancer Driver No 1 hippie 46 61 8 8 0
AK4 AK4 P27144 Adenylate kinase 4, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 26 24 3 3 0
ALDH18A1 ALDH18A1 P54886 Delta-1-pyrroline-5-carboxylate synthase chr10 Not Cancer Driver No 1 hippie 94 86 13 13 15
AMACR_ENST00000335606 AMACR Q9UHK6 Alpha-methylacyl-CoA racemase chr5 Not Cancer Driver No 1 hippie, biogrid 56 38 8 8 3
AOC3 AOC3 Q16853 Membrane primary amine oxidase chr17 Not Cancer Driver No 1 hippie 112 101 13 13 0
ARHGEF26 ARHGEF26 Q96DR7 Rho guanine nucleotide exchange factor 26 chr3 Not Cancer Driver No 1 hippie, biogrid 164 475 86 86 0
AUH AUH Q13825 Methylglutaconyl-CoA hydratase, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 34 29 0 0 1
BBS1 BBS1 Q8NFJ9 Bardet-Biedl syndrome 1 protein chr11 Not Cancer Driver No 1 hippie 69 99 14 14 12
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
BPNT1_ENST00000322067 BPNT1 O95861 3'(2'),5'-bisphosphate nucleotidase 1 chr1 Not Cancer Driver No 1 hippie, biogrid 44 9 0 0 0
C1QBP C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 14 103 6 6 2
C20orf96 C20orf96 Q9NUD7 Uncharacterized protein C20orf96 chr20 Not Cancer Driver No 1 hippie, biogrid 39 148 17 17 0
CBR4 CBR4 Q8N4T8 3-oxoacyl-[acyl-carrier-protein] reductase chr4 Not Cancer Driver No 1 hippie, biogrid 15 4 0 0 0
CDIPT_ENST00000569956 CDIPT O14735 CDP-diacylglycerol--inositol 3-phosphatidyltransferase chr16 Not Cancer Driver No 1 hippie 21 0 0 0 0
COL8A2_ENST00000303143 COL8A2 P25067 Collagen alpha-2(VIII) chain chr1 Not Cancer Driver No 1 hippie 75 559 58 58 4
COX8A COX8A P10176 Cytochrome c oxidase subunit 8A, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 10 1 0 0 0
CS CS O75390 Citrate synthase, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 50 13 2 2 0
CYB561_ENST00000392976 CYB561 P49447 Transmembrane ascorbate-dependent reductase CYB561 chr17 Not Cancer Driver No 1 hippie 28 6 0 0 1
DCP2 DCP2 Q8IU60 m7GpppN-mRNA hydrolase chr5 Not Cancer Driver No 1 hippie 57 167 24 24 0
DNAJA3 DNAJA3 Q96EY1 DnaJ homolog subfamily A member 3, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 50 152 21 21 0
DNAJC2 DNAJC2 Q99543 DnaJ homolog subfamily C member 2 chr7 Not Cancer Driver No 1 hippie, biogrid 67 425 48 48 0
DPYSL5 DPYSL5 Q9BPU6 Dihydropyrimidinase-related protein 5 chr2 Not Cancer Driver No 1 hippie 132 115 28 28 2
EFTUD2 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 132 179 30 30 3
EPHA8 EPHA8 P29322 Ephrin type-A receptor 8 chr1 Not Cancer Driver No 1 hippie 197 121 17 17 0
ETFBKMT_ENST00000412352 ETFBKMT Q8IXQ9 Electron transfer flavoprotein beta subunit lysine methyltransferase chr12 Not Cancer Driver No 1 hippie 25 0 0 0 0
EXD2 EXD2 Q9NVH0 Exonuclease 3'-5' domain-containing protein 2 chr14 Not Cancer Driver No 1 hippie, biogrid 58 176 15 15 0
FAHD1_ENST00000427358 FAHD1 Q6P587 Acylpyruvase FAHD1, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 15 12 0 0 0
FBXO15 FBXO15 Q8NCQ5 F-box only protein 15 chr18 Not Cancer Driver No 1 hippie 86 0 0 0 0
FEM1A FEM1A Q9BSK4 Protein fem-1 homolog A chr19 Not Cancer Driver No 1 hippie, biogrid 68 162 22 22 0
FETUB_ENST00000450521 FETUB Q9UGM5 Fetuin-B chr3 Not Cancer Driver No 1 hippie 76 119 30 30 0
FNTA FNTA P49354 Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha chr8 Not Cancer Driver No 1 hippie, biogrid 43 92 12 12 0
FOXB1 FOXB1 Q99853 Forkhead box protein B1 chr15 Not Cancer Driver No 1 hippie 31 114 5 5 0
FOXH1 FOXH1 O75593 Forkhead box protein H1 chr8 Not Cancer Driver No 1 hippie 47 215 25 25 0
FOXI2 FOXI2 Q6ZQN5 Forkhead box protein I2 chr10 Not Cancer Driver No 1 hippie 32 165 22 22 0
FOXL1 FOXL1 Q12952 Forkhead box protein L1 chr16 Not Cancer Driver No 1 hippie 62 212 26 26 0
FOXL2 FOXL2 P58012 Forkhead box protein L2 chr3 Census, Compendium Yes 1 hippie 39 257 20 20 26
FSCN1 FSCN1 Q16658 Fascin chr7 Not Cancer Driver No 1 hippie 58 81 5 5 0
GAPDHS GAPDHS O14556 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific chr19 Not Cancer Driver No 2 hippie, biogrid 71 111 19 19 0
GCAT_ENST00000248924 GCAT O75600 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial chr22 Not Cancer Driver No 1 hippie, biogrid 59 2 0 0 0
GLYATL1_ENST00000612196 GLYATL1 Q969I3 Glycine N-acyltransferase-like protein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 98 30 22 22 0
HSCB HSCB Q8IWL3 Iron-sulfur cluster co-chaperone protein HscB chr22 Not Cancer Driver No 1 hippie 36 25 6 6 0
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 2 hippie, biogrid 61 82 6 6 2
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
KLHL20 KLHL20 Q9Y2M5 Kelch-like protein 20 chr1 Not Cancer Driver No 1 hippie, biogrid 83 143 17 17 0
LAMP3 LAMP3 Q9UQV4 Lysosome-associated membrane glycoprotein 3 chr3 Not Cancer Driver No 2 hippie, biogrid 67 222 38 38 0
LCN1 LCN1 P31025 Lipocalin-1 chr9 Not Cancer Driver No 1 hippie, biogrid 31 69 17 17 0
LDHAL6B LDHAL6B Q9BYZ2 L-lactate dehydrogenase A-like 6B chr15 Not Cancer Driver No 1 hippie, biogrid 54 17 2 2 0
LMBR1L LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 57 4 0 0 0
MALSU1 MALSU1 Q96EH3 Mitochondrial assembly of ribosomal large subunit protein 1 chr7 Not Cancer Driver No 1 hippie, biogrid 17 34 0 0 0
MCUR1 MCUR1 Q96AQ8 Mitochondrial calcium uniporter regulator 1 chr6 Not Cancer Driver No 1 hippie, biogrid 30 65 0 0 0
MGST3 MGST3 O14880 Microsomal glutathione S-transferase 3 chr1 Not Cancer Driver No 1 hippie 17 0 0 0 0
MRM2_ENST00000440306 MRM2 Q9UI43 rRNA methyltransferase 2, mitochondrial chr7 Not Cancer Driver No 1 hippie 37 15 1 1 1
MRPL12 MRPL12 P52815 39S ribosomal protein L12, mitochondrial chr17 Not Cancer Driver No 2 hippie, biogrid 21 22 6 6 1
MRPL21 MRPL21 Q7Z2W9 39S ribosomal protein L21, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 25 20 0 0 0
MRPS2 MRPS2 Q9Y399 28S ribosomal protein S2, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 32 57 6 6 3
MRPS24 MRPS24 Q96EL2 28S ribosomal protein S24, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 20 1 0 0 0
MRPS30 MRPS30 Q9NP92 39S ribosomal protein S30, mitochondrial chr5 Not Cancer Driver No 1 hippie, biogrid 54 53 10 10 0
MTG2 MTG2 Q9H4K7 Mitochondrial ribosome-associated GTPase 2 chr20 Not Cancer Driver No 2 hippie, biogrid 57 47 9 9 0
MTIF2_ENST00000403721 MTIF2 P46199 Translation initiation factor IF-2, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 101 112 9 9 0
MTRF1L MTRF1L Q9UGC7 Peptide chain release factor 1-like, mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 31 183 12 12 0
MYL10 MYL10 Q9BUA6 Myosin regulatory light chain 10 chr7 Not Cancer Driver No 1 hippie, biogrid 40 49 7 7 0
NARS2 NARS2 Q96I59 Probable asparagine--tRNA ligase, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 79 22 2 2 3
NDUFS7 NDUFS7 O75251 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial chr19 Not Cancer Driver No 1 hippie, biogrid 36 30 3 3 1
NEDD8 NEDD8 Q15843 NEDD8 chr14 Not Cancer Driver No 1 hippie 10 36 5 5 0
NIPSNAP3A NIPSNAP3A Q9UFN0 Protein NipSnap homolog 3A chr9 Not Cancer Driver No 1 hippie, biogrid 26 15 4 4 0
NR2C2_ENST00000393102 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 hippie 62 186 24 24 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
OCIAD1 OCIAD1 Q9NX40 OCIA domain-containing protein 1 chr4 Not Cancer Driver No 1 hippie, biogrid 37 169 25 25 0
OPTN_ENST00000263036 OPTN Q96CV9 Optineurin chr10 Not Cancer Driver No 1 hippie 58 470 51 51 6
OXCT2 OXCT2 Q9BYC2 Succinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 55 56 6 6 0
PDHA1_ENST00000422285 PDHA1 P08559 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial chrX Not Cancer Driver No 1 hippie, biogrid 70 43 6 6 20
PDK1_ENST00000282077 PDK1 Q15118 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial chr2 Not Cancer Driver No 1 hippie 52 50 10 10 0
PLAUR PLAUR Q03405 Urokinase plasminogen activator surface receptor chr19 Not Cancer Driver No 1 hippie, biogrid 49 18 5 5 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PLP2 PLP2 Q04941 Proteolipid protein 2 chrX Not Cancer Driver No 1 hippie 40 10 3 3 0
POR POR P16435 NADPH--cytochrome P450 reductase chr7 Not Cancer Driver No 1 hippie, biogrid 62 93 4 4 9
QRSL1 QRSL1 Q9H0R6 Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 63 63 4 4 2
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 138 608 71 71 1
RHOA RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 99 46 13 13 2
RNF123 RNF123 Q5XPI4 E3 ubiquitin-protein ligase RNF123 chr3 Not Cancer Driver No 1 hippie 167 220 28 28 0
RPA2_ENST00000373912 RPA2 P15927 Replication protein A 32 kDa subunit chr1 Not Cancer Driver No 1 hippie, biogrid 28 114 16 16 0
SHC2 SHC2 P98077 SHC-transforming protein 2 chr19 Not Cancer Driver No 1 hippie, biogrid 66 362 44 44 0
SLC16A11 SLC16A11 Q8NCK7 Monocarboxylate transporter 11 chr17 Not Cancer Driver No 1 hippie 33 72 5 5 0
SLC25A10_ENST00000350690 SLC25A10 Q9UBX3 Mitochondrial dicarboxylate carrier chr17 Not Cancer Driver No 1 hippie, biogrid 33 0 0 0 0
SQSTM1 SQSTM1 Q13501 Sequestosome-1 chr5 Not Cancer Driver No 1 hippie 54 267 32 32 30
SSBP1_ENST00000484178 SSBP1 Q04837 Single-stranded DNA-binding protein, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 27 0 0 0 6
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 hippie 10 76 7 7 0
SYVN1 SYVN1 Q86TM6 E3 ubiquitin-protein ligase synoviolin chr11 Not Cancer Driver No 1 hippie 63 284 32 32 0
TERF2 TERF2 Q15554 Telomeric repeat-binding factor 2 chr16 Not Cancer Driver No 1 hippie 33 361 20 20 0
THSD7B THSD7B Q9C0I4 Thrombospondin type-1 domain-containing protein 7B chr2 Not Cancer Driver No 1 hippie 652 94 19 19 0
TMEM239 TMEM239 Q8WW34 Transmembrane protein 239 chr20 Not Cancer Driver No 1 hippie 5 27 0 0 0
TRAP1 TRAP1 Q12931 Heat shock protein 75 kDa, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 74 110 11 11 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 87 430 41 41 0
TRIM43 TRIM43 Q96BQ3 Tripartite motif-containing protein 43 chr2 Not Cancer Driver No 1 hippie, biogrid 48 28 7 7 0
TRMT61B TRMT61B Q9BVS5 tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial chr2 Not Cancer Driver No 1 hippie 48 123 10 10 0
TRMU TRMU O75648 Mitochondrial tRNA-specific 2-thiouridylase 1 chr22 Not Cancer Driver No 1 hippie, biogrid 40 28 5 5 2
TSPAN33 TSPAN33 Q86UF1 Tetraspanin-33 chr7 Not Cancer Driver No 1 hippie 26 0 0 0 0
UBD UBD O15205 Ubiquitin D chr6 Not Cancer Driver No 1 hippie 31 8 1 1 0
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 hippie 109 141 24 24 0
UNC50_ENST00000357765 UNC50 Q53HI1 Protein unc-50 homolog chr2 Not Cancer Driver No 1 hippie 21 0 0 0 0
UQCRFS1 UQCRFS1 P47985 Cytochrome b-c1 complex subunit Rieske, mitochondrial chr19 Not Cancer Driver No 1 hippie, biogrid 43 47 4 4 1
YARS2 YARS2 Q9Y2Z4 Tyrosine--tRNA ligase, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 59 62 11 11 2
YBEY_ENST00000397691 YBEY P58557 Endoribonuclease YbeY chr21 Not Cancer Driver No 2 hippie, biogrid 19 9 2 2 0
ZUP1 ZUP1 Q96AP4 Zinc finger-containing ubiquitin peptidase 1 chr6 Not Cancer Driver No 1 hippie 63 204 19 19 0