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CYB5R1 ,CYB5R1 ,Q9UHQ9
  • Uniprot Accession= Q9UHQ9
  • Ensembl Transcript= ENST00000367249.8
  • Uniprot Name= CYB5R1
  • Name= NADH-cytochrome b5 reductase 1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 90
  • Number of Interaction partner in hippie: 113
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACOT9_ENST00000336430 ACOT9 Q9Y305 Acyl-coenzyme A thioesterase 9, mitochondrial chrX Not Cancer Driver No 1 hippie, biogrid 45 45 3 3 0
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 1 hippie, biogrid 112 43 5 5 5
AGPS AGPS O00116 Alkyldihydroxyacetonephosphate synthase, peroxisomal chr2 Not Cancer Driver No 1 hippie, biogrid 68 151 10 10 6
AKAP1_ENST00000539273 AKAP1 Q92667 A-kinase anchor protein 1, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 107 537 67 67 0
ANLN ANLN Q9NQW6 Anillin chr7 Not Cancer Driver No 1 hippie 144 767 104 104 2
APOE APOE P02649 Apolipoprotein E chr19 Not Cancer Driver No 1 hippie, biogrid 25 124 6 6 12
AQP3 AQP3 Q92482 Aquaporin-3 chr9 Not Cancer Driver No 1 hippie, biogrid 34 12 0 0 0
ATP2A1 ATP2A1 O14983 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 chr16 Not Cancer Driver No 2 hippie, biogrid 157 80 11 11 1
ATP2A3_ENST00000397041 ATP2A3 Q93084 Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 chr17 Not Cancer Driver No 1 hippie, biogrid 130 147 16 16 0
ATP5F1A_ENST00000282050 ATP5F1A P25705 ATP synthase subunit alpha, mitochondrial chr18 Not Cancer Driver No 1 hippie 66 23 5 5 2
ATP5F1B ATP5F1B P06576 ATP synthase subunit beta, mitochondrial chr12 Not Cancer Driver No 1 hippie 60 85 8 8 0
ATP5MG ATP5MG O75964 ATP synthase subunit g, mitochondrial chr11 Not Cancer Driver No 1 hippie 16 0 0 0 0
ATP6V1B2 ATP6V1B2 P21281 V-type proton ATPase subunit B, brain isoform chr8 Not Cancer Driver No 1 hippie, biogrid 63 49 4 4 1
BTNL3 BTNL3 Q6UXE8 Butyrophilin-like protein 3 chr5 Not Cancer Driver No 1 hippie, biogrid 79 50 13 13 0
C1orf54 C1orf54 Q8WWF1 Uncharacterized protein C1orf54 chr1 Not Cancer Driver No 1 hippie, biogrid 17 28 3 3 0
CACNG1 CACNG1 Q06432 Voltage-dependent calcium channel gamma-1 subunit chr17 Not Cancer Driver No 1 hippie, biogrid 36 0 0 0 0
CCR1 CCR1 P32246 C-C chemokine receptor type 1 chr3 Not Cancer Driver No 1 hippie, biogrid 69 14 5 5 0
CCT8L2 CCT8L2 Q96SF2 T-complex protein 1 subunit theta-like 2 chr22 Not Cancer Driver No 1 hippie, biogrid 216 104 46 46 0
CHRNA4 CHRNA4 P43681 Neuronal acetylcholine receptor subunit alpha-4 chr20 Not Cancer Driver No 1 hippie, biogrid 144 186 33 33 2
CHRNB2 CHRNB2 P17787 Neuronal acetylcholine receptor subunit beta-2 chr1 Not Cancer Driver No 1 hippie, biogrid 92 23 2 2 2
CHRNB4 CHRNB4 P30926 Neuronal acetylcholine receptor subunit beta-4 chr15 Not Cancer Driver No 1 hippie, biogrid 98 30 6 6 0
CHRNE CHRNE Q04844 Acetylcholine receptor subunit epsilon chr17 Not Cancer Driver No 1 hippie, biogrid 52 37 3 3 13
COQ9 COQ9 O75208 Ubiquinone biosynthesis protein COQ9, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 43 111 13 13 0
COX6B1_ENST00000592141 COX6B1 P14854 Cytochrome c oxidase subunit 6B1 chr19 Not Cancer Driver No 1 hippie 15 23 6 6 2
CYB5B CYB5B O43169 Cytochrome b5 type B chr16 Not Cancer Driver No 1 hippie, biogrid 17 58 2 2 0
CYB5R3_ENST00000352397 CYB5R3 P00387 NADH-cytochrome b5 reductase 3 chr22 Not Cancer Driver No 1 hippie, biogrid 42 24 3 3 9
CYCS_ENST00000409409 CYCS P99999 Cytochrome c chr7 Not Cancer Driver No 1 hippie 12 19 3 3 1
DERL1 DERL1 Q9BUN8 Derlin-1 chr8 Not Cancer Driver No 1 hippie, biogrid 28 11 1 1 0
EMC1 EMC1 Q8N766 ER membrane protein complex subunit 1 chr1 Not Cancer Driver No 1 hippie 107 59 6 6 2
EMC4 EMC4 Q5J8M3 ER membrane protein complex subunit 4 chr15 Not Cancer Driver No 1 hippie 15 17 2 2 0
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
GNG5_ENST00000370645 GNG5 P63218 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 chr1 Not Cancer Driver No 1 hippie, biogrid 5 9 1 1 0
HADHA HADHA P40939 Trifunctional enzyme subunit alpha, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 72 19 2 2 5
HADHB HADHB P55084 Trifunctional enzyme subunit beta, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 71 41 9 9 14
HEPACAM2_ENST00000394468 HEPACAM2 A8MVW5 HEPACAM family member 2 chr7 Not Cancer Driver No 3 hippie, biogrid 115 50 14 14 0
HIGD1C HIGD1C A8MV81 HIG1 domain family member 1C chr12 Not Cancer Driver No 1 hippie 8 10 0 0 0
HRAS HRAS P01112 GTPase HRas chr11 Census, Compendium Yes 1 hippie 107 16 4 4 18
HSCB HSCB Q8IWL3 Iron-sulfur cluster co-chaperone protein HscB chr22 Not Cancer Driver No 1 hippie 36 25 6 6 0
HSD17B4_ENST00000256216 HSD17B4 P51659 Peroxisomal multifunctional enzyme type 2 chr5 Not Cancer Driver No 1 hippie, biogrid 99 82 12 12 4
HTR3B HTR3B O95264 5-hydroxytryptamine receptor 3B chr11 Not Cancer Driver No 1 hippie, biogrid 91 8 0 0 0
IL20RA IL20RA Q9UHF4 Interleukin-20 receptor subunit alpha chr6 Not Cancer Driver No 2 hippie, biogrid 72 231 29 29 0
IL22RA1 IL22RA1 Q8N6P7 Interleukin-22 receptor subunit alpha-1 chr1 Not Cancer Driver No 1 hippie, biogrid 66 297 37 37 0
KCNA2_ENST00000638616 KCNA2 P16389 Potassium voltage-gated channel subfamily A member 2 chr1 Not Cancer Driver No 1 hippie, biogrid 96 82 16 16 5
KCNA5 KCNA5 P22460 Potassium voltage-gated channel subfamily A member 5 chr12 Not Cancer Driver No 2 hippie, biogrid 213 218 53 53 0
KRAS KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 1 hippie, biogrid 788 7 2 2 27
LETM1 LETM1 O95202 Mitochondrial proton/calcium exchanger protein chr4 Not Cancer Driver No 1 hippie, biogrid 77 286 28 28 0
LRRC55 LRRC55 A0A494C0H1 Leucine-rich repeat-containing protein 55 chr11 Not Cancer Driver No 1 hippie, biogrid 90 3 1 1 0
LRRC59 LRRC59 Q96AG4 Leucine-rich repeat-containing protein 59 chr17 Not Cancer Driver No 1 hippie, biogrid 33 122 15 15 0
LY6G6F LY6G6F Q5SQ64 Lymphocyte antigen 6 complex locus protein G6f chr6 Not Cancer Driver No 1 hippie, biogrid 49 32 4 4 0
MAGEA8_ENST00000542674 MAGEA8 P43361 Melanoma-associated antigen 8 chrX Not Cancer Driver No 1 hippie, biogrid 65 112 19 19 0
MCOLN3 MCOLN3 Q8TDD5 Mucolipin-3 chr1 Not Cancer Driver No 3 hippie, biogrid 102 9 2 2 0
MFSD8_ENST00000296468 MFSD8 Q8NHS3 Major facilitator superfamily domain-containing protein 8 chr4 Not Cancer Driver No 2 hippie, biogrid 69 16 3 3 16
MGST1_ENST00000396210 MGST1 P10620 Microsomal glutathione S-transferase 1 chr12 Not Cancer Driver No 1 hippie, biogrid 26 0 0 0 0
MPV17 MPV17 P39210 Protein Mpv17 chr2 Not Cancer Driver No 1 hippie, biogrid 21 0 0 0 16
MRPS23 MRPS23 Q9Y3D9 28S ribosomal protein S23, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 21 58 6 6 1
MTCH2 MTCH2 Q9Y6C9 Mitochondrial carrier homolog 2 chr11 Not Cancer Driver No 1 hippie, biogrid 45 11 0 0 0
NAAA NAAA Q02083 N-acylethanolamine-hydrolyzing acid amidase chr4 Not Cancer Driver No 3 hippie, biogrid 42 43 3 3 0
NCAPD3 NCAPD3 P42695 Condensin-2 complex subunit D3 chr11 Not Cancer Driver No 1 hippie 193 304 42 42 1
NDUFA3 NDUFA3 O95167 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 chr19 Not Cancer Driver No 1 hippie, biogrid 7 27 4 4 0
NDUFA8 NDUFA8 P51970 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 chr9 Not Cancer Driver No 1 hippie, biogrid 25 33 1 1 2
NKAIN1 NKAIN1 Q4KMZ8 Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 20 0 0 0 0
NRAS NRAS P01111 GTPase NRas chr1 Census, Compendium Yes 1 hippie, biogrid 284 10 0 0 14
OCIAD1 OCIAD1 Q9NX40 OCIA domain-containing protein 1 chr4 Not Cancer Driver No 1 hippie, biogrid 37 169 25 25 0
OCIAD2 OCIAD2 Q56VL3 OCIA domain-containing protein 2 chr4 Not Cancer Driver No 1 hippie, biogrid 21 27 4 4 0
OGDH OGDH Q02218 2-oxoglutarate dehydrogenase complex component E1 chr7 Not Cancer Driver No 1 hippie, biogrid 150 106 19 19 0
PANX1 PANX1 Q96RD7 Pannexin-1 chr11 Not Cancer Driver No 1 hippie, biogrid 54 45 7 7 2
PCDHA11 PCDHA11 Q9Y5I1 Protocadherin alpha-11 chr5 Not Cancer Driver No 1 hippie, biogrid 306 337 86 86 0
PCDHGA5 PCDHGA5 Q9Y5G8 Protocadherin gamma-A5 chr5 Not Cancer Driver No 2 hippie, biogrid 253 339 75 75 0
PCDHGB2 PCDHGB2 Q9Y5G2 Protocadherin gamma-B2 chr5 Not Cancer Driver No 1 hippie, biogrid 221 364 71 71 0
PCDHGC4 PCDHGC4 Q9Y5F7 Protocadherin gamma-C4 chr5 Not Cancer Driver No 1 hippie, biogrid 136 460 59 59 0
PDGFRA PDGFRA P16234 Platelet-derived growth factor receptor alpha chr4 Census, Compendium Yes 1 hippie, biogrid 290 173 45 45 2
PDHA1_ENST00000422285 PDHA1 P08559 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial chrX Not Cancer Driver No 1 hippie, biogrid 70 43 6 6 20
PHB2 PHB2 Q99623 Prohibitin-2 chr12 Not Cancer Driver No 1 hippie, biogrid 31 26 4 4 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 57 99 13 13 23
PPP2R2B_ENST00000394409 PPP2R2B Q00005 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform chr5 Not Cancer Driver No 1 hippie, biogrid 101 76 22 22 0
PRDX3 PRDX3 P30048 Thioredoxin-dependent peroxide reductase, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 23 23 3 3 0
PREB PREB Q9HCU5 Prolactin regulatory element-binding protein chr2 Not Cancer Driver No 1 hippie, biogrid 56 91 10 10 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 Not Cancer Driver No 1 hippie 110 78 15 15 31
RAB1A RAB1A P62820 Ras-related protein Rab-1A chr2 Not Cancer Driver No 1 hippie, biogrid 16 38 2 2 0
RAB7A RAB7A P51149 Ras-related protein Rab-7a chr3 Not Cancer Driver No 1 hippie, biogrid 27 11 0 0 4
RXFP1_ENST00000307765 RXFP1 Q9HBX9 Relaxin receptor 1 chr4 Not Cancer Driver No 1 hippie, biogrid 152 0 0 0 0
SCCPDH SCCPDH Q8NBX0 Saccharopine dehydrogenase-like oxidoreductase chr1 Not Cancer Driver No 1 hippie, biogrid 56 26 1 1 0
SCGB2A2 SCGB2A2 Q13296 Mammaglobin-A chr11 Not Cancer Driver No 1 hippie, biogrid 11 0 0 0 0
SCN4A SCN4A P35499 Sodium channel protein type 4 subunit alpha chr17 Not Cancer Driver No 1 hippie, biogrid 324 372 80 80 60
SFXN1 SFXN1 Q9H9B4 Sideroflexin-1 chr5 Not Cancer Driver No 1 hippie, biogrid 31 29 1 1 0
SGTA SGTA O43765 Small glutamine-rich tetratricopeptide repeat-containing protein alpha chr19 Not Cancer Driver No 1 hippie 38 159 23 23 0
SGTB SGTB Q96EQ0 Small glutamine-rich tetratricopeptide repeat-containing protein beta chr5 Not Cancer Driver No 1 hippie 28 114 10 10 0
SH2D3C SH2D3C Q8N5H7 SH2 domain-containing protein 3C chr9 Not Cancer Driver No 1 hippie 110 440 72 72 0
SIRT4 SIRT4 Q9Y6E7 NAD-dependent protein lipoamidase sirtuin-4, mitochondrial chr12 Not Cancer Driver No 1 hippie 46 4 0 0 0
SLC22A4 SLC22A4 Q9H015 Solute carrier family 22 member 4 chr5 Not Cancer Driver No 1 hippie, biogrid 57 8 2 2 0
SLC25A20 SLC25A20 O43772 Mitochondrial carnitine/acylcarnitine carrier protein chr3 Not Cancer Driver No 1 hippie, biogrid 39 17 3 3 3
SLC25A3 SLC25A3 Q00325 Phosphate carrier protein, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 49 32 4 4 1
SLC31A1 SLC31A1 O15431 High affinity copper uptake protein 1 chr9 Not Cancer Driver No 1 hippie, biogrid 22 28 6 6 0
SLC51B SLC51B Q86UW2 Organic solute transporter subunit beta chr15 Not Cancer Driver No 1 hippie 9 58 5 5 0
SLC7A1 SLC7A1 P30825 High affinity cationic amino acid transporter 1 chr13 Not Cancer Driver No 2 hippie, biogrid 89 17 3 3 0
SLC7A14 SLC7A14 Q8TBB6 Probable cationic amino acid transporter chr3 Not Cancer Driver No 1 hippie, biogrid 146 61 15 15 4
SPATA7 SPATA7 Q9P0W8 Spermatogenesis-associated protein 7 chr14 Not Cancer Driver No 1 hippie, biogrid 89 408 70 70 0
SSUH2 SSUH2 Q9Y2M2 Protein SSUH2 homolog chr3 Not Cancer Driver No 1 hippie, biogrid 58 76 7 7 0
TEX101_ENST00000598265 TEX101 Q9BY14 Testis-expressed protein 101 chr19 Not Cancer Driver No 1 hippie 45 2 0 0 0
TMEM106A TMEM106A Q96A25 Transmembrane protein 106A chr17 Not Cancer Driver No 1 hippie, biogrid 26 9 1 1 0
TMEM30A TMEM30A Q9NV96 Cell cycle control protein 50A chr6 Not Cancer Driver No 2 hippie, biogrid 50 76 8 8 0
TOMM6_ENST00000398881 TOMM6 Q96B49 Mitochondrial import receptor subunit TOM6 homolog chr6 Not Cancer Driver No 1 hippie, biogrid 6 18 2 2 0
TSPAN15 TSPAN15 O95858 Tetraspanin-15 chr10 Not Cancer Driver No 1 hippie, biogrid 29 0 0 0 0
TTC1 TTC1 Q99614 Tetratricopeptide repeat protein 1 chr5 Not Cancer Driver No 1 hippie 28 211 21 21 0
TTYH1_ENST00000376530 TTYH1 Q9H313 Protein tweety homolog 1 chr19 Not Cancer Driver No 1 hippie, biogrid 56 21 3 3 0
UBQLN1 UBQLN1 Q9UMX0 Ubiquilin-1 chr9 Not Cancer Driver No 1 hippie 64 543 58 58 0
UBQLN4 UBQLN4 Q9NRR5 Ubiquilin-4 chr1 Not Cancer Driver No 1 hippie 70 561 67 67 1
UQCRC1 UQCRC1 P31930 Cytochrome b-c1 complex subunit 1, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 57 55 6 6 2
UQCRC2 UQCRC2 P22695 Cytochrome b-c1 complex subunit 2, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 53 48 13 13 1
VDAC2_ENST00000543351 VDAC2 P45880 Voltage-dependent anion-selective channel protein 2 chr10 Not Cancer Driver No 1 hippie, biogrid 35 9 1 1 0
VDAC3_ENST00000022615 VDAC3 Q9Y277 Voltage-dependent anion-selective channel protein 3 chr8 Not Cancer Driver No 1 hippie, biogrid 24 0 0 0 0
ZACN ZACN Q401N2 Zinc-activated ligand-gated ion channel chr17 Not Cancer Driver No 1 hippie, biogrid 46 48 6 6 0
ZNRF4 ZNRF4 Q8WWF5 E3 ubiquitin-protein ligase ZNRF4 chr19 Not Cancer Driver No 2 hippie, biogrid 115 99 26 26 0