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CTPS1 ,CTPS1 ,P17812
  • Uniprot Accession= P17812
  • Ensembl Transcript= ENST00000372621.8
  • Uniprot Name= CTPS1
  • Name= CTP synthase 1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 26
  • Number of Interaction partner in biogrid: 28
  • Number of Interaction partner in hippie: 138
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AAR2_ENST00000320849 AAR2 Q9Y312 Protein AAR2 homolog chr20 Not Cancer Driver No 1 hippie 56 28 6 6 0
ACO1_ENST00000541043 ACO1 P21399 Cytoplasmic aconitate hydratase chr9 Not Cancer Driver No 1 hippie 108 44 14 14 0
ANKRD55 ANKRD55 Q3KP44 Ankyrin repeat domain-containing protein 55 chr5 Not Cancer Driver No 1 hippie 95 339 63 63 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 Not Cancer Driver No 1 hippie 46 122 22 22 0
AURKA_ENST00000395915 AURKA O14965 Aurora kinase A chr20 Not Cancer Driver No 1 hippie 36 178 21 21 0
BCAR3_ENST00000260502 BCAR3 O75815 Breast cancer anti-estrogen resistance protein 3 chr1 Not Cancer Driver No 1 hippie 102 395 42 42 0
BCL2L14 BCL2L14 Q9BZR8 Apoptosis facilitator Bcl-2-like protein 14 chr12 Not Cancer Driver No 1 hippie 29 40 4 4 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 224 1458 174 174 35
BRD7_ENST00000394688 BRD7 Q9NPI1 Bromodomain-containing protein 7 chr16 Compendium Yes 1 hippie 82 482 57 57 0
CALCOCO2_ENST00000258947 CALCOCO2 Q13137 Calcium-binding and coiled-coil domain-containing protein 2 chr17 Not Cancer Driver No 1 hippie 42 212 19 19 0
CAND1 CAND1 Q86VP6 Cullin-associated NEDD8-dissociated protein 1 chr12 Not Cancer Driver No 1 hippie 161 88 7 7 0
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 Not Cancer Driver No 1 hippie 24 0 0 0 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 3 intact, hippie 287 145 18 18 151
CIC CIC Q96RK0 Protein capicua homolog chr19 Census, Compendium Yes 1 hippie 276 1550 266 266 0
CLNS1A_ENST00000528364 CLNS1A P54105 Methylosome subunit pICln chr11 Not Cancer Driver No 1 hippie 19 170 13 13 0
COPS5 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 Not Cancer Driver No 1 hippie 36 32 7 7 0
CS CS O75390 Citrate synthase, mitochondrial chr12 Not Cancer Driver No 1 hippie 50 13 2 2 0
CSNK1E CSNK1E P49674 Casein kinase I isoform epsilon chr22 Not Cancer Driver No 1 hippie 62 133 18 18 0
CTBP2_ENST00000494626 CTBP2 P56545 C-terminal-binding protein 2 chr10 Not Cancer Driver No 1 hippie, biogrid 48 94 4 4 0
CTPS1 CTPS1 P17812 CTP synthase 1 chr1 Not Cancer Driver No 2 intact, hippie 70 83 10 10 0
CTPS2_ENST00000380241 CTPS2 Q9NRF8 CTP synthase 2 chrX Not Cancer Driver No 2 hippie, biogrid 57 65 9 9 0
CUL1_ENST00000602748 CUL1 Q13616 Cullin-1 chr7 Not Cancer Driver No 1 intact, hippie 151 65 9 9 0
CUL2_ENST00000374748 CUL2 Q13617 Cullin-2 chr10 Not Cancer Driver No 1 intact, hippie 87 66 3 3 0
CUL3 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 intact, hippie 123 167 23 23 3
CUL4B CUL4B Q13620 Cullin-4B chrX Not Cancer Driver No 1 intact, hippie 138 207 38 38 2
CUL5 CUL5 Q93034 Cullin-5 chr11 Not Cancer Driver No 1 intact, hippie 97 5 1 1 0
CYLD CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 Census, Compendium Yes 1 hippie 116 213 31 31 3
DCTPP1 DCTPP1 Q9H773 dCTP pyrophosphatase 1 chr16 Not Cancer Driver No 1 hippie 14 88 9 9 0
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 Not Cancer Driver No 1 hippie 34 181 23 23 0
DDX3X_ENST00000629496 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX Census, Compendium Yes 1 hippie 133 301 47 47 18
DFFA DFFA O00273 DNA fragmentation factor subunit alpha chr1 Not Cancer Driver No 1 hippie 47 113 18 18 0
EFTUD2 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 132 179 30 30 3
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
EIF4B_ENST00000262056 EIF4B P23588 Eukaryotic translation initiation factor 4B chr12 Not Cancer Driver No 1 hippie, biogrid 94 589 90 90 0
ERCC2 ERCC2 P18074 General transcription and DNA repair factor IIH helicase subunit XPD chr19 Census, Compendium Yes 1 hippie, biogrid 150 5 0 0 35
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
FAM107A_ENST00000394481 FAM107A O95990 Actin-associated protein FAM107A chr3 Not Cancer Driver No 1 hippie 25 141 24 24 0
FBXO32 FBXO32 Q969P5 F-box only protein 32 chr8 Not Cancer Driver No 1 hippie 54 0 0 0 0
FBXO6 FBXO6 Q9NRD1 F-box only protein 6 chr1 Not Cancer Driver No 1 hippie 31 27 3 3 0
GABARAP GABARAP O95166 Gamma-aminobutyric acid receptor-associated protein chr17 Not Cancer Driver No 1 hippie 9 11 0 0 0
GABARAPL1_ENST00000545887 GABARAPL1 Q9H0R8 Gamma-aminobutyric acid receptor-associated protein-like 1 chr12 Not Cancer Driver No 1 hippie 19 10 1 1 0
GABARAPL2 GABARAPL2 P60520 Gamma-aminobutyric acid receptor-associated protein-like 2 chr16 Not Cancer Driver No 1 hippie 11 2 1 1 0
GINS3_ENST00000318129 GINS3 Q9BRX5 DNA replication complex GINS protein PSF3 chr16 Not Cancer Driver No 1 hippie 36 14 0 0 0
GMPS GMPS P49915 GMP synthase [glutamine-hydrolyzing] chr3 Census, Compendium Yes 1 hippie, biogrid 88 76 10 10 0
GRN GRN P28799 Progranulin chr17 Not Cancer Driver No 1 hippie 76 29 6 6 1
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 Not Cancer Driver No 1 hippie 56 146 13 13 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 Not Cancer Driver No 1 hippie 46 145 14 14 0
HIST1H2AJ H2AC14 Q99878 Histone H2A type 1-J chr6 Not Cancer Driver No 1 intact 28 56 11 11 0
HLA-B HLA-B P01889 HLA class I histocompatibility antigen, B alpha chain chr6 Compendium Yes 1 hippie 78 169 34 34 0
HLA-C HLA-C P10321 HLA class I histocompatibility antigen, C alpha chain chr6 Not Cancer Driver No 1 hippie 104 175 58 58 0
HSD17B10 HSD17B10 Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 chrX Not Cancer Driver No 1 intact, hippie, biogrid 27 15 3 3 11
IKBKE IKBKE Q14164 Inhibitor of nuclear factor kappa-B kinase subunit epsilon chr1 Not Cancer Driver No 1 intact, hippie 108 76 13 13 0
IMPDH1_ENST00000626419 IMPDH1 P20839 Inosine-5'-monophosphate dehydrogenase 1 chr7 Not Cancer Driver No 1 hippie, biogrid 75 13 1 1 7
IMPDH2 IMPDH2 P12268 Inosine-5'-monophosphate dehydrogenase 2 chr3 Not Cancer Driver No 1 hippie, biogrid 70 6 1 1 0
KDF1 KDF1 Q8NAX2 Keratinocyte differentiation factor 1 chr1 Not Cancer Driver No 1 hippie, biogrid 61 277 50 50 0
KIF23 KIF23 Q02241 Kinesin-like protein KIF23 chr15 Not Cancer Driver No 1 hippie 102 559 62 62 0
LCA5 LCA5 Q86VQ0 Lebercilin chr6 Not Cancer Driver No 1 intact, hippie 102 597 82 82 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 519 90 17 17 23
MAGEL2 MAGEL2 Q9UJ55 MAGE-like protein 2 chr15 Not Cancer Driver No 1 hippie 178 1010 118 118 0
MAP1LC3A_ENST00000397709 MAP1LC3A Q9H492 Microtubule-associated proteins 1A/1B light chain 3A chr20 Not Cancer Driver No 1 hippie 22 24 1 1 0
MAP1LC3B MAP1LC3B Q9GZQ8 Microtubule-associated proteins 1A/1B light chain 3B chr16 Not Cancer Driver No 1 intact, hippie 10 17 1 1 0
MAP2K3 MAP2K3 P46734 Dual specificity mitogen-activated protein kinase kinase 3 chr17 Not Cancer Driver No 1 hippie 104 75 27 27 0
MCM2 MCM2 P49736 DNA replication licensing factor MCM2 chr3 Not Cancer Driver No 1 hippie 104 275 38 38 1
MECOM_ENST00000494292 MECOM Q03112 Histone-lysine N-methyltransferase MECOM chr3 Census, Compendium Yes 1 hippie 287 749 159 159 3
MTREX MTREX P42285 Exosome RNA helicase MTR4 chr5 Not Cancer Driver No 1 hippie 117 160 15 15 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
NAA40 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 22 30 3 3 0
NEDD8 NEDD8 Q15843 NEDD8 chr14 Not Cancer Driver No 1 hippie 10 36 5 5 0
NEK7 NEK7 Q8TDX7 Serine/threonine-protein kinase Nek7 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 35 23 0 0 0
NMD3_ENST00000351193 NMD3 Q96D46 60S ribosomal export protein NMD3 chr3 Not Cancer Driver No 1 hippie, biogrid 67 104 20 20 0
NR2C2_ENST00000393102 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 hippie 62 186 24 24 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
OFD1 OFD1 O75665 Oral-facial-digital syndrome 1 protein chrX Not Cancer Driver No 1 hippie 129 476 58 58 5
OTUB1_ENST00000428192 OTUB1 Q96FW1 Ubiquitin thioesterase OTUB1 chr11 Not Cancer Driver No 1 intact, hippie 31 33 2 2 0
PAPSS1 PAPSS1 O43252 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 chr4 Not Cancer Driver No 1 hippie 94 82 14 14 0
PCLAF PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 20 111 20 20 0
PDCD10_ENST00000473645 PDCD10 Q9BUL8 Programmed cell death protein 10 chr3 Not Cancer Driver No 1 hippie, biogrid 32 25 4 4 0
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 30 157 13 13 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 Not Cancer Driver No 1 hippie 57 99 13 13 23
PINX1 PINX1 Q96BK5 PIN2/TERF1-interacting telomerase inhibitor 1 chr8 Not Cancer Driver No 1 hippie 66 328 66 66 0
PKM_ENST00000335181 PKM P14618 Pyruvate kinase PKM chr15 Not Cancer Driver No 1 hippie 78 58 13 13 0
PLCG1_ENST00000373271 PLCG1 P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 chr20 Census, Compendium Yes 1 hippie, biogrid 158 186 21 21 0
PLD6 PLD6 Q8N2A8 Mitochondrial cardiolipin hydrolase chr17 Not Cancer Driver No 1 biogrid 27 24 6 6 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
POLR1C POLR1C O15160 DNA-directed RNA polymerases I and III subunit RPAC1 chr6 Not Cancer Driver No 1 hippie, biogrid 34 28 3 3 13
PPEF1 PPEF1 O14829 Serine/threonine-protein phosphatase with EF-hands 1 chrX Not Cancer Driver No 1 intact, hippie 127 66 10 10 0
PPP5C PPP5C P53041 Serine/threonine-protein phosphatase 5 chr19 Not Cancer Driver No 1 hippie 70 73 12 12 0
PRKAB1 PRKAB1 Q9Y478 5'-AMP-activated protein kinase subunit beta-1 chr12 Not Cancer Driver No 1 intact, hippie 39 124 13 13 0
PRMT1 PRMT1 Q99873 Protein arginine N-methyltransferase 1 chr19 Not Cancer Driver No 1 hippie, biogrid 50 18 1 1 0
PRMT5 PRMT5 O14744 Protein arginine N-methyltransferase 5 chr14 Not Cancer Driver No 1 hippie, biogrid 83 72 6 6 0
PRPF8 PRPF8 Q6P2Q9 Pre-mRNA-processing-splicing factor 8 chr17 Not Cancer Driver No 1 hippie 255 225 26 26 8
PSMA3 PSMA3 P25788 Proteasome subunit alpha type-3 chr14 Not Cancer Driver No 1 hippie 27 30 5 5 0
PTBP3_ENST00000374255 PTBP3 O95758 Polypyrimidine tract-binding protein 3 chr9 Not Cancer Driver No 1 intact, hippie 61 114 9 9 0
PUS7_ENST00000469408 PUS7 Q96PZ0 Pseudouridylate synthase 7 homolog chr7 Not Cancer Driver No 1 hippie, biogrid 73 162 17 17 1
RAD21 RAD21 O60216 Double-strand-break repair protein rad21 homolog chr8 Census, Compendium Yes 1 hippie 115 421 74 74 3
RBM28 RBM28 Q9NW13 RNA-binding protein 28 chr7 Not Cancer Driver No 1 hippie, biogrid 97 512 66 66 1
RBM39 RBM39 Q14498 RNA-binding protein 39 chr20 Compendium Yes 1 hippie 81 228 39 39 0
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 138 608 71 71 1
RIN3 RIN3 Q8TB24 Ras and Rab interactor 3 chr14 Not Cancer Driver No 1 intact, hippie 137 417 61 61 0
RNF123 RNF123 Q5XPI4 E3 ubiquitin-protein ligase RNF123 chr3 Not Cancer Driver No 1 hippie 167 220 28 28 0
RPGRIP1L_ENST00000379925 RPGRIP1L Q68CZ1 Protein fantom chr16 Not Cancer Driver No 1 intact, hippie 177 586 94 94 8
RTF2_ENST00000357348 RTF2 Q9BY42 Replication termination factor 2 chr20 Not Cancer Driver No 1 hippie 44 170 22 22 0
RUNX1_ENST00000344691 RUNX1 Q01196 Runt-related transcription factor 1 chr21 Census, Compendium Yes 1 hippie 81 360 58 58 2
SNAI1 SNAI1 O95863 Zinc finger protein SNAI1 chr20 Not Cancer Driver No 1 hippie 52 97 11 11 0
SNU13_ENST00000355257 SNU13 P55769 NHP2-like protein 1 chr22 Not Cancer Driver No 1 hippie 17 2 0 0 0
SNX2 SNX2 O60749 Sorting nexin-2 chr5 Not Cancer Driver No 1 hippie, biogrid 45 218 18 18 0
SNX3 SNX3 O60493 Sorting nexin-3 chr6 Not Cancer Driver No 1 hippie 21 37 4 4 0
SPRTN SPRTN Q9H040 DNA-dependent metalloprotease SPRTN chr1 Not Cancer Driver No 1 hippie 73 252 38 38 1
SQSTM1 SQSTM1 Q13501 Sequestosome-1 chr5 Not Cancer Driver No 1 hippie 54 267 32 32 30
STAU1 STAU1 O95793 Double-stranded RNA-binding protein Staufen homolog 1 chr20 Not Cancer Driver No 1 hippie 77 456 63 63 0
STRAP STRAP Q9Y3F4 Serine-threonine kinase receptor-associated protein chr12 Not Cancer Driver No 1 hippie, biogrid 44 40 5 5 0
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 hippie 10 76 7 7 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
SUMO3_ENST00000332859 SUMO3 P55854 Small ubiquitin-related modifier 3 chr21 Not Cancer Driver No 1 hippie 7 87 5 5 0
TIFAB TIFAB Q6ZNK6 TRAF-interacting protein with FHA domain-containing protein B chr5 Not Cancer Driver No 1 intact, hippie 32 26 7 7 0
TIGD3 TIGD3 Q6B0B8 Tigger transposable element-derived protein 3 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 77 99 21 21 0
TMPO TMPO P42166 Lamina-associated polypeptide 2, isoform alpha chr12 Not Cancer Driver No 1 hippie 78 412 52 52 0
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 Not Cancer Driver No 1 intact, hippie, biogrid 67 62 7 7 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 87 430 41 41 0
TRMT1_ENST00000357720 TRMT1 Q9NXH9 tRNA (guanine(26)-N(2))-dimethyltransferase chr19 Not Cancer Driver No 1 hippie, biogrid 82 200 24 24 0
TSN TSN Q15631 Translin chr2 Not Cancer Driver No 1 hippie, biogrid 30 0 0 0 0
TTC4 TTC4 O95801 Tetratricopeptide repeat protein 4 chr1 Not Cancer Driver No 1 hippie, biogrid 45 100 12 12 0
TUBGCP3 TUBGCP3 Q96CW5 Gamma-tubulin complex component 3 chr13 Not Cancer Driver No 1 hippie 109 156 16 16 0
TXNIP TXNIP Q9H3M7 Thioredoxin-interacting protein chr1 Not Cancer Driver No 1 hippie 61 77 14 14 0
UBA1 UBA1 P22314 Ubiquitin-like modifier-activating enzyme 1 chrX Not Cancer Driver No 1 hippie 117 165 22 22 6
UBA6 UBA6 A0AVT1 Ubiquitin-like modifier-activating enzyme 6 chr4 Not Cancer Driver No 2 hippie, biogrid 133 90 10 10 0
UBR5 UBR5 O95071 E3 ubiquitin-protein ligase UBR5 chr8 Census, Compendium Yes 1 hippie 340 1296 162 162 0
UBXN1_ENST00000301935 UBXN1 Q04323 UBX domain-containing protein 1 chr11 Not Cancer Driver No 1 hippie 35 271 33 33 0
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 hippie 109 141 24 24 0
USP11 USP11 P51784 Ubiquitin carboxyl-terminal hydrolase 11 chrX Not Cancer Driver No 1 hippie 140 210 28 28 0
VCL VCL P18206 Vinculin chr10 Not Cancer Driver No 1 hippie 114 673 80 80 2
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
WDR36 WDR36 Q8NI36 WD repeat-containing protein 36 chr5 Not Cancer Driver No 1 hippie, biogrid 140 89 11 11 2
WWOX WWOX Q9NZC7 WW domain-containing oxidoreductase chr16 Not Cancer Driver No 1 hippie 79 108 9 9 3
YWHAB_ENST00000353703 YWHAB P31946 14-3-3 protein beta/alpha chr20 Not Cancer Driver No 1 intact, hippie 22 109 4 4 0
YWHAG YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 2 intact, hippie 26 77 9 9 2
YWHAQ YWHAQ P27348 14-3-3 protein theta chr2 Not Cancer Driver No 1 hippie 29 41 6 6 0
YWHAZ_ENST00000395956 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 1 intact, hippie 30 81 10 10 0