Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AGO1 | AGO1 | Q9UL18 | Protein argonaute-1 | chr1 | Not Cancer Driver | No | 1 | hippie | 126 | 87 | 11 | 11 | 0 |
AGO2 | AGO2 | Q9UKV8 | Protein argonaute-2 | chr8 | Not Cancer Driver | No | 1 | hippie | 126 | 141 | 15 | 15 | 11 |
AKT2 | AKT2 | P31751 | RAC-beta serine/threonine-protein kinase | chr19 | Census | Yes | 1 | hippie | 77 | 84 | 9 | 9 | 2 |
AKT3_ENST00000366539 | AKT3 | Q9Y243 | RAC-gamma serine/threonine-protein kinase | chr1 | Census, Compendium | Yes | 1 | hippie | 92 | 131 | 24 | 24 | 3 |
ALG13 | ALG13 | Q9NP73 | Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 | chrX | Not Cancer Driver | No | 1 | hippie | 163 | 520 | 83 | 83 | 2 |
ARFGEF3 | ARFGEF3 | Q5TH69 | Brefeldin A-inhibited guanine nucleotide-exchange protein 3 | chr6 | Not Cancer Driver | No | 1 | hippie | 258 | 584 | 58 | 58 | 0 |
ARHGEF39 | ARHGEF39 | Q8N4T4 | Rho guanine nucleotide exchange factor 39 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 45 | 56 | 5 | 5 | 0 |
ATP1A3_ENST00000302102 | ATP1A3 | P13637 | Sodium/potassium-transporting ATPase subunit alpha-3 | chr19 | Not Cancer Driver | No | 1 | hippie | 200 | 115 | 29 | 29 | 31 |
ATP6V1B2 | ATP6V1B2 | P21281 | V-type proton ATPase subunit B, brain isoform | chr8 | Not Cancer Driver | No | 1 | hippie | 63 | 49 | 4 | 4 | 1 |
ATXN2_ENST00000550104 | ATXN2 | Q99700 | Ataxin-2 | chr12 | Not Cancer Driver | No | 1 | hippie | 146 | 1228 | 134 | 134 | 0 |
BAG2 | BAG2 | O95816 | BAG family molecular chaperone regulator 2 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 17 | 112 | 9 | 9 | 0 |
BICC1 | BICC1 | Q9H694 | Protein bicaudal C homolog 1 | chr10 | Not Cancer Driver | No | 1 | hippie | 171 | 645 | 115 | 115 | 1 |
BICD2_ENST00000375512 | BICD2 | Q8TD16 | Protein bicaudal D homolog 2 | chr9 | Not Cancer Driver | No | 1 | hippie | 115 | 546 | 73 | 73 | 10 |
BMI1 | BMI1 | P35226 | Polycomb complex protein BMI-1 | chr10 | Not Cancer Driver | No | 1 | hippie | 50 | 150 | 30 | 30 | 0 |
BRCA1_ENST00000357654 | BRCA1 | P38398 | Breast cancer type 1 susceptibility protein | chr17 | Census, Compendium | Yes | 1 | hippie | 224 | 1458 | 174 | 174 | 35 |
BRD4 | BRD4 | O60885 | Bromodomain-containing protein 4 | chr19 | Census, Compendium | Yes | 1 | hippie | 193 | 1182 | 172 | 172 | 0 |
BTF3 | BTF3 | P20290 | Transcription factor BTF3 | chr5 | Not Cancer Driver | No | 1 | hippie | 27 | 192 | 24 | 24 | 0 |
C11orf68_ENST00000449692 | C11orf68 | Q9H3H3 | UPF0696 protein C11orf68 | chr11 | Not Cancer Driver | No | 1 | hippie | 18 | 139 | 6 | 6 | 0 |
CADPS | CADPS | Q9ULU8 | Calcium-dependent secretion activator 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 298 | 336 | 71 | 71 | 0 |
CAPRIN1_ENST00000532820 | CAPRIN1 | Q14444 | Caprin-1 | chr11 | Not Cancer Driver | No | 1 | hippie | 84 | 603 | 72 | 72 | 0 |
CELF1_ENST00000358597 | CELF1 | Q92879 | CUGBP Elav-like family member 1 | chr11 | Not Cancer Driver | No | 1 | hippie | 56 | 166 | 17 | 17 | 0 |
CLEC14A | CLEC14A | Q86T13 | C-type lectin domain family 14 member A | chr14 | Not Cancer Driver | No | 1 | hippie | 147 | 182 | 60 | 60 | 0 |
CNOT1 | CNOT1 | A5YKK6 | CCR4-NOT transcription complex subunit 1 | chr16 | Not Cancer Driver | No | 1 | hippie | 346 | 464 | 56 | 56 | 12 |
COPS5 | COPS5 | Q92905 | COP9 signalosome complex subunit 5 | chr8 | Not Cancer Driver | No | 1 | hippie | 36 | 32 | 7 | 7 | 0 |
CTIF_ENST00000256413 | CTIF | O43310 | CBP80/20-dependent translation initiation factor | chr18 | Not Cancer Driver | No | 1 | hippie | 97 | 384 | 62 | 62 | 0 |
CUL1_ENST00000602748 | CUL1 | Q13616 | Cullin-1 | chr7 | Not Cancer Driver | No | 1 | hippie | 151 | 65 | 9 | 9 | 0 |
CUL3 | CUL3 | Q13618 | Cullin-3 | chr2 | Census, Compendium | Yes | 1 | hippie | 123 | 167 | 23 | 23 | 3 |
CYLD | CYLD | Q9NQC7 | Ubiquitin carboxyl-terminal hydrolase CYLD | chr16 | Census, Compendium | Yes | 1 | hippie | 116 | 213 | 31 | 31 | 3 |
DAZL_ENST00000399444 | DAZL | Q92904 | Deleted in azoospermia-like | chr3 | Not Cancer Driver | No | 1 | hippie | 28 | 128 | 12 | 12 | 0 |
DDRGK1 | DDRGK1 | Q96HY6 | DDRGK domain-containing protein 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 34 | 181 | 23 | 23 | 0 |
DDX3X_ENST00000629496 | DDX3X | O00571 | ATP-dependent RNA helicase DDX3X | chrX | Census, Compendium | Yes | 1 | hippie | 133 | 301 | 47 | 47 | 18 |
DDX6 | DDX6 | P26196 | Probable ATP-dependent RNA helicase DDX6 | chr11 | Census, Compendium | Yes | 1 | hippie | 44 | 129 | 7 | 7 | 5 |
DHX57 | DHX57 | Q6P158 | Putative ATP-dependent RNA helicase DHX57 | chr2 | Not Cancer Driver | No | 1 | hippie | 147 | 294 | 32 | 32 | 0 |
DISC1_ENST00000439617 | DISC1 | Q9NRI5 | Disrupted in schizophrenia 1 protein | chr1 | Not Cancer Driver | No | 1 | hippie | 132 | 514 | 82 | 82 | 0 |
EFTUD2 | EFTUD2 | Q15029 | 116 kDa U5 small nuclear ribonucleoprotein component | chr17 | Compendium | Yes | 1 | hippie | 132 | 179 | 30 | 30 | 3 |
EIF4ENIF1 | EIF4ENIF1 | Q9NRA8 | Eukaryotic translation initiation factor 4E transporter | chr22 | Not Cancer Driver | No | 1 | hippie | 116 | 899 | 101 | 101 | 0 |
ELAVL1 | ELAVL1 | Q15717 | ELAV-like protein 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 69 | 43 | 5 | 5 | 0 |
EP300 | EP300 | Q09472 | Histone acetyltransferase p300 | chr22 | Census, Compendium | Yes | 1 | hippie | 334 | 1790 | 196 | 196 | 1 |
ERBB2 | ERBB2 | P04626 | Receptor tyrosine-protein kinase erbB-2 | chr17 | Census, Compendium | Yes | 1 | hippie | 275 | 314 | 41 | 41 | 1 |
ESR1_ENST00000206249 | ESR1 | P03372 | Estrogen receptor | chr6 | Census, Compendium | Yes | 1 | hippie | 121 | 195 | 27 | 27 | 2 |
ESR2 | ESR2 | Q92731 | Estrogen receptor beta | chr14 | Not Cancer Driver | No | 1 | hippie | 90 | 92 | 11 | 11 | 1 |
FABP5 | FABP5 | Q01469 | Fatty acid-binding protein 5 | chr8 | Not Cancer Driver | No | 1 | hippie | 15 | 4 | 4 | 4 | 0 |
FAM120A | FAM120A | Q9NZB2 | Constitutive coactivator of PPAR-gamma-like protein 1 | chr9 | Not Cancer Driver | No | 1 | hippie | 123 | 516 | 58 | 58 | 0 |
FAM120C | FAM120C | Q9NX05 | Constitutive coactivator of PPAR-gamma-like protein 2 | chrX | Not Cancer Driver | No | 1 | hippie | 162 | 508 | 77 | 77 | 0 |
FAM19A3_ENST00000361886 | TAFA3 | Q7Z5A8 | Chemokine-like protein TAFA-3 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 17 | 6 | 0 | 0 | 0 |
FAM9B | FAM9B | Q8IZU0 | Protein FAM9B | chrX | Not Cancer Driver | No | 1 | hippie | 40 | 130 | 29 | 29 | 0 |
FBL | FBL | P22087 | rRNA 2'-O-methyltransferase fibrillarin | chr19 | Not Cancer Driver | No | 2 | hippie, biogrid | 46 | 145 | 22 | 22 | 0 |
FLNB_ENST00000295956 | FLNB | O75369 | Filamin-B | chr3 | Not Cancer Driver | No | 1 | hippie | 362 | 1183 | 170 | 170 | 19 |
FMR1 | FMR1 | Q06787 | Synaptic functional regulator FMR1 | chrX | Not Cancer Driver | No | 1 | hippie | 124 | 327 | 70 | 70 | 3 |
FUBP3 | FUBP3 | Q96I24 | Far upstream element-binding protein 3 | chr9 | Not Cancer Driver | No | 1 | hippie | 68 | 353 | 51 | 51 | 0 |
FXR1 | FXR1 | P51114 | Fragile X mental retardation syndrome-related protein 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 88 | 312 | 53 | 53 | 0 |
FZR1 | FZR1 | Q9UM11 | Fizzy-related protein homolog | chr19 | Not Cancer Driver | No | 1 | hippie | 74 | 184 | 30 | 30 | 0 |
G3BP1 | G3BP1 | Q13283 | Ras GTPase-activating protein-binding protein 1 | chr5 | Not Cancer Driver | No | 1 | hippie | 85 | 352 | 65 | 65 | 0 |
G3BP2_ENST00000395719 | G3BP2 | Q9UN86 | Ras GTPase-activating protein-binding protein 2 | chr4 | Not Cancer Driver | No | 1 | hippie | 64 | 384 | 53 | 53 | 0 |
GANAB_ENST00000356638 | GANAB | Q14697 | Neutral alpha-glucosidase AB | chr11 | Not Cancer Driver | No | 1 | hippie | 129 | 132 | 20 | 20 | 3 |
GBF1 | GBF1 | Q92538 | Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 | chr10 | Not Cancer Driver | No | 1 | hippie | 216 | 669 | 76 | 76 | 0 |
GH1 | GH1 | P01241 | Somatotropin | chr17 | Not Cancer Driver | No | 1 | hippie | 54 | 24 | 9 | 9 | 15 |
GMPPB_ENST00000480687 | GMPPB | Q9Y5P6 | Mannose-1-phosphate guanyltransferase beta | chr3 | Not Cancer Driver | No | 1 | hippie | 39 | 10 | 1 | 1 | 19 |
GNAO1_ENST00000638705 | GNAO1 | P09471 | Guanine nucleotide-binding protein G(o) subunit alpha | chr16 | Not Cancer Driver | No | 1 | hippie | 54 | 10 | 0 | 0 | 15 |
GSK3B_ENST00000264235 | GSK3B | P49841 | Glycogen synthase kinase-3 beta | chr3 | Not Cancer Driver | No | 1 | hippie | 56 | 146 | 13 | 13 | 0 |
HDAC2 | HDAC2 | Q92769 | Histone deacetylase 2 | chr6 | Not Cancer Driver | No | 1 | hippie | 46 | 145 | 14 | 14 | 0 |
HEATR5A | HEATR5A | Q86XA9 | HEAT repeat-containing protein 5A | chr14 | Not Cancer Driver | No | 1 | hippie | 189 | 124 | 18 | 18 | 0 |
HID1 | HID1 | Q8IV36 | Protein HID1 | chr17 | Not Cancer Driver | No | 2 | intact, hippie | 102 | 153 | 14 | 14 | 0 |
HLA-B | HLA-B | P01889 | HLA class I histocompatibility antigen, B alpha chain | chr6 | Compendium | Yes | 1 | hippie | 78 | 169 | 34 | 34 | 0 |
HNRNPA1 | HNRNPA1 | P09651 | Heterogeneous nuclear ribonucleoprotein A1 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 70 | 290 | 58 | 58 | 4 |
HNRNPD | HNRNPD | Q14103 | Heterogeneous nuclear ribonucleoprotein D0 | chr4 | Not Cancer Driver | No | 1 | hippie | 39 | 206 | 19 | 19 | 0 |
HNRNPL | HNRNPL | P14866 | Heterogeneous nuclear ribonucleoprotein L | chr19 | Not Cancer Driver | No | 1 | hippie | 89 | 283 | 29 | 29 | 0 |
HOOK3 | HOOK3 | Q86VS8 | Protein Hook homolog 3 | chr8 | Census | Yes | 1 | hippie | 79 | 493 | 55 | 55 | 0 |
HSPA1A | HSPA1A | P0DMV8 | Heat shock 70 kDa protein 1A | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 200 | 13 | 13 | 0 |
HSPA8_ENST00000532636 | HSPA8 | P11142 | Heat shock cognate 71 kDa protein | chr11 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 149 | 251 | 52 | 52 | 0 |
HUWE1_ENST00000262854 | HUWE1 | Q7Z6Z7 | E3 ubiquitin-protein ligase HUWE1 | chrX | Not Cancer Driver | No | 1 | hippie | 669 | 2091 | 329 | 329 | 21 |
IGF2BP1 | IGF2BP1 | Q9NZI8 | Insulin-like growth factor 2 mRNA-binding protein 1 | chr17 | Not Cancer Driver | No | 1 | hippie | 141 | 298 | 80 | 80 | 0 |
IGF2BP2_ENST00000382199 | IGF2BP2 | Q9Y6M1 | Insulin-like growth factor 2 mRNA-binding protein 2 | chr3 | Census | Yes | 1 | hippie | 68 | 237 | 31 | 31 | 0 |
JUN | JUN | P05412 | Transcription factor Jun | chr1 | Census | Yes | 1 | hippie | 35 | 281 | 25 | 25 | 0 |
JUP | JUP | P14923 | Junction plakoglobin | chr17 | Not Cancer Driver | No | 1 | hippie | 112 | 241 | 37 | 37 | 0 |
KIF14 | KIF14 | Q15058 | Kinesin-like protein KIF14 | chr1 | Not Cancer Driver | No | 1 | hippie | 222 | 774 | 102 | 102 | 2 |
KIF1B_ENST00000377086 | KIF1B | O60333 | Kinesin-like protein KIF1B | chr1 | Not Cancer Driver | No | 1 | hippie | 253 | 633 | 106 | 106 | 1 |
KIF1C | KIF1C | O43896 | Kinesin-like protein KIF1C | chr17 | Not Cancer Driver | No | 1 | hippie | 131 | 695 | 94 | 94 | 1 |
KSR1_ENST00000644974 | KSR1 | Q8IVT5 | Kinase suppressor of Ras 1 | chr17 | Not Cancer Driver | No | 1 | hippie | 114 | 404 | 58 | 58 | 0 |
LARP4B | LARP4B | Q92615 | La-related protein 4B | chr10 | Census | Yes | 1 | hippie | 127 | 521 | 91 | 91 | 0 |
LARP4_ENST00000398473 | LARP4 | Q71RC2 | La-related protein 4 | chr12 | Not Cancer Driver | No | 1 | hippie | 86 | 486 | 53 | 53 | 0 |
LMBR1L | LMBR1L | Q6UX01 | Protein LMBR1L | chr12 | Not Cancer Driver | No | 1 | hippie | 57 | 4 | 0 | 0 | 0 |
LRRK2 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | Not Cancer Driver | No | 1 | intact | 519 | 90 | 17 | 17 | 23 |
LSM12 | LSM12 | Q3MHD2 | Protein LSM12 homolog | chr17 | Not Cancer Driver | No | 1 | hippie | 13 | 66 | 7 | 7 | 0 |
MAFB | MAFB | Q9Y5Q3 | Transcription factor MafB | chr20 | Census | Yes | 1 | hippie | 35 | 301 | 34 | 34 | 10 |
MCC_ENST00000302475 | MCC | P23508 | Colorectal mutant cancer protein | chr5 | Not Cancer Driver | No | 1 | hippie | 136 | 589 | 92 | 92 | 0 |
MCRIP2 | MCRIP2 | Q9BUT9 | MAPK regulated corepressor interacting protein 2 | chr16 | Not Cancer Driver | No | 1 | hippie | 8 | 141 | 7 | 7 | 0 |
MDM2_ENST00000539479 | MDM2 | Q00987 | E3 ubiquitin-protein ligase Mdm2 | chr12 | Census, Compendium | Yes | 1 | hippie | 56 | 297 | 37 | 37 | 0 |
MEX3B | MEX3B | Q6ZN04 | RNA-binding protein MEX3B | chr15 | Not Cancer Driver | No | 1 | hippie | 85 | 437 | 64 | 64 | 0 |
MKRN2 | MKRN2 | Q9H000 | E3 ubiquitin-protein ligase makorin-2 | chr3 | Not Cancer Driver | No | 1 | hippie | 45 | 145 | 16 | 16 | 0 |
MKRN3 | MKRN3 | Q13064 | Probable E3 ubiquitin-protein ligase makorin-3 | chr15 | Not Cancer Driver | No | 1 | hippie | 197 | 201 | 99 | 99 | 4 |
MOV10_ENST00000357443 | MOV10 | Q9HCE1 | Helicase MOV-10 | chr1 | Not Cancer Driver | No | 1 | hippie | 110 | 101 | 8 | 8 | 0 |
MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | Census, Compendium | Yes | 1 | hippie | 80 | 299 | 46 | 46 | 0 |
NAA40 | NAA40 | Q86UY6 | N-alpha-acetyltransferase 40 | chr11 | Not Cancer Driver | No | 1 | hippie | 22 | 30 | 3 | 3 | 0 |
NBR1 | NBR1 | Q14596 | Next to BRCA1 gene 1 protein | chr17 | Not Cancer Driver | No | 1 | hippie | 101 | 560 | 51 | 51 | 0 |
NCK1_ENST00000288986 | NCK1 | P16333 | Cytoplasmic protein NCK1 | chr3 | Not Cancer Driver | No | 1 | hippie | 48 | 111 | 17 | 17 | 0 |
NDN | NDN | Q99608 | Necdin | chr15 | Not Cancer Driver | No | 1 | hippie | 123 | 117 | 42 | 42 | 0 |
NR2C2_ENST00000393102 | NR2C2 | P49116 | Nuclear receptor subfamily 2 group C member 2 | chr3 | Not Cancer Driver | No | 1 | hippie | 62 | 186 | 24 | 24 | 0 |
NTRK1 | NTRK1 | P04629 | High affinity nerve growth factor receptor | chr1 | Census, Compendium | Yes | 1 | hippie | 168 | 57 | 8 | 8 | 25 |
NUP188 | NUP188 | Q5SRE5 | Nucleoporin NUP188 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 190 | 152 | 20 | 20 | 0 |
NUP98_ENST00000359171 | NUP98 | P52948 | Nuclear pore complex protein Nup98-Nup96 | chr11 | Census | Yes | 1 | hippie | 227 | 1008 | 107 | 107 | 0 |
OTUB1_ENST00000428192 | OTUB1 | Q96FW1 | Ubiquitin thioesterase OTUB1 | chr11 | Not Cancer Driver | No | 1 | hippie | 31 | 33 | 2 | 2 | 0 |
OTUD4_ENST00000447906 | OTUD4 | Q01804 | OTU domain-containing protein 4 | chr4 | Not Cancer Driver | No | 1 | hippie | 148 | 788 | 120 | 120 | 0 |
P2RY6_ENST00000540342 | P2RY6 | Q15077 | P2Y purinoceptor 6 | chr11 | Not Cancer Driver | No | 1 | hippie | 50 | 10 | 5 | 5 | 0 |
PABPC1 | PABPC1 | P11940 | Polyadenylate-binding protein 1 | chr8 | Census, Compendium | Yes | 1 | hippie | 100 | 317 | 55 | 55 | 0 |
PABPC4L | PABPC4L | P0CB38 | Polyadenylate-binding protein 4-like | chr4 | Not Cancer Driver | No | 1 | hippie | 44 | 29 | 1 | 1 | 0 |
PABPC5 | PABPC5 | Q96DU9 | Polyadenylate-binding protein 5 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 132 | 26 | 9 | 9 | 0 |
PAIP1 | PAIP1 | Q9H074 | Polyadenylate-binding protein-interacting protein 1 | chr5 | Not Cancer Driver | No | 1 | hippie | 67 | 259 | 36 | 36 | 0 |
PAK2 | PAK2 | Q13177 | Serine/threonine-protein kinase PAK 2 | chr3 | Compendium | Yes | 1 | hippie | 89 | 242 | 49 | 49 | 0 |
PCLAF | PCLAF | Q15004 | PCNA-associated factor | chr15 | Not Cancer Driver | No | 1 | hippie | 20 | 111 | 20 | 20 | 0 |
PCSK7 | PCSK7 | Q16549 | Proprotein convertase subtilisin/kexin type 7 | chr11 | Not Cancer Driver | No | 1 | hippie | 101 | 262 | 31 | 31 | 0 |
PDE3A | PDE3A | Q14432 | cGMP-inhibited 3',5'-cyclic phosphodiesterase A | chr12 | Not Cancer Driver | No | 1 | hippie | 274 | 527 | 114 | 114 | 6 |
PI16 | PI16 | Q6UXB8 | Peptidase inhibitor 16 | chr6 | Not Cancer Driver | No | 1 | hippie | 64 | 256 | 28 | 28 | 0 |
PIK3R1 | PIK3R1 | P27986 | Phosphatidylinositol 3-kinase regulatory subunit alpha | chr5 | Census, Compendium | Yes | 1 | hippie | 154 | 268 | 61 | 61 | 2 |
PLEKHA3 | PLEKHA3 | Q9HB20 | Pleckstrin homology domain-containing family A member 3 | chr2 | Not Cancer Driver | No | 1 | hippie | 30 | 159 | 19 | 19 | 0 |
PLEKHA4 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 136 | 687 | 128 | 128 | 0 |
PLOD2_ENST00000360060 | PLOD2 | O00469 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 | chr3 | Not Cancer Driver | No | 1 | hippie | 109 | 17 | 3 | 3 | 4 |
PPIA | PPIA | P62937 | Peptidyl-prolyl cis-trans isomerase A | chr7 | Not Cancer Driver | No | 1 | hippie | 11 | 24 | 3 | 3 | 0 |
PRKAB1 | PRKAB1 | Q9Y478 | 5'-AMP-activated protein kinase subunit beta-1 | chr12 | Not Cancer Driver | No | 1 | hippie | 39 | 124 | 13 | 13 | 0 |
PRKD1_ENST00000616995 | PRKD1 | Q15139 | Serine/threonine-protein kinase D1 | chr14 | Census | Yes | 1 | hippie | 201 | 189 | 33 | 33 | 2 |
PRKN | PRKN | O60260 | E3 ubiquitin-protein ligase parkin | chr6 | Not Cancer Driver | No | 1 | hippie | 110 | 78 | 15 | 15 | 31 |
PRRC2A_ENST00000376007 | PRRC2A | P48634 | Protein PRRC2A | chr6 | Not Cancer Driver | No | 1 | hippie | 253 | 2119 | 249 | 249 | 0 |
PRRC2B | PRRC2B | Q5JSZ5 | Protein PRRC2B | chr9 | Not Cancer Driver | No | 1 | hippie | 279 | 2199 | 278 | 278 | 0 |
PRRC2C | PRRC2C | Q9Y520-4 | Isoform 4 of Protein PRRC2C | chr1 | Not Cancer Driver | No | 1 | hippie | 296 | 2713 | 287 | 287 | 0 |
PUM1_ENST00000257075 | PUM1 | Q14671 | Pumilio homolog 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 150 | 640 | 77 | 77 | 3 |
RBM47_ENST00000295971 | RBM47 | A0AV96 | RNA-binding protein 47 | chr4 | Not Cancer Driver | No | 1 | hippie | 143 | 131 | 28 | 28 | 0 |
RC3H1_ENST00000258349 | RC3H1 | Q5TC82 | Roquin-1 | chr1 | Not Cancer Driver | No | 1 | hippie | 158 | 796 | 115 | 115 | 0 |
RECQL4 | RECQL4 | O94761 | ATP-dependent DNA helicase Q4 | chr8 | Census, Compendium | Yes | 1 | hippie | 138 | 608 | 71 | 71 | 1 |
RHBDD1 | RHBDD1 | Q8TEB9 | Rhomboid-related protein 4 | chr2 | Not Cancer Driver | No | 1 | hippie | 38 | 69 | 9 | 9 | 0 |
RHBDF2 | RHBDF2 | Q6PJF5 | Inactive rhomboid protein 2 | chr17 | Not Cancer Driver | No | 1 | hippie | 93 | 284 | 36 | 36 | 2 |
RIN3 | RIN3 | Q8TB24 | Ras and Rab interactor 3 | chr14 | Not Cancer Driver | No | 1 | intact, hippie | 137 | 417 | 61 | 61 | 0 |
RIOK1 | RIOK1 | Q9BRS2 | Serine/threonine-protein kinase RIO1 | chr6 | Not Cancer Driver | No | 1 | hippie | 69 | 301 | 37 | 37 | 0 |
RPS20_ENST00000521262 | RPS20 | P60866 | 40S ribosomal protein S20 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 53 | 8 | 8 | 0 |
RPS6KA1_ENST00000374168 | RPS6KA1 | Q15418 | Ribosomal protein S6 kinase alpha-1 | chr1 | Not Cancer Driver | No | 1 | hippie | 94 | 178 | 32 | 32 | 0 |
RYBP | RYBP | Q8N488 | RING1 and YY1-binding protein | chr3 | Not Cancer Driver | No | 1 | hippie | 37 | 214 | 37 | 37 | 0 |
SAMD4A | SAMD4A | Q9UPU9 | Protein Smaug homolog 1 | chr14 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 83 | 473 | 55 | 55 | 0 |
SEC24C | SEC24C | P53992 | Protein transport protein Sec24C | chr10 | Not Cancer Driver | No | 1 | hippie | 121 | 402 | 38 | 38 | 0 |
SECISBP2 | SECISBP2 | Q96T21 | Selenocysteine insertion sequence-binding protein 2 | chr9 | Not Cancer Driver | No | 1 | hippie | 90 | 565 | 50 | 50 | 1 |
SENP3_ENST00000429205 | SENP3 | Q9H4L4 | Sentrin-specific protease 3 | chr17 | Not Cancer Driver | No | 1 | hippie | 53 | 288 | 30 | 30 | 0 |
SERBP1 | SERBP1 | Q8NC51 | Plasminogen activator inhibitor 1 RNA-binding protein | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 53 | 408 | 53 | 53 | 0 |
SIRT7 | SIRT7 | Q9NRC8 | NAD-dependent protein deacetylase sirtuin-7 | chr17 | Not Cancer Driver | No | 1 | hippie | 48 | 163 | 15 | 15 | 0 |
SMG7_ENST00000347615 | SMG7 | Q92540 | Nonsense-mediated mRNA decay factor SMG7 | chr1 | Not Cancer Driver | No | 1 | hippie | 134 | 664 | 82 | 82 | 0 |
SNRNP70 | SNRNP70 | P08621 | U1 small nuclear ribonucleoprotein 70 kDa | chr19 | Not Cancer Driver | No | 1 | hippie | 38 | 416 | 37 | 37 | 0 |
SNW1_ENST00000261531 | SNW1 | Q13573 | SNW domain-containing protein 1 | chr14 | Not Cancer Driver | No | 1 | hippie | 62 | 488 | 56 | 56 | 0 |
SSRP1 | SSRP1 | Q08945 | FACT complex subunit SSRP1 | chr11 | Not Cancer Driver | No | 1 | hippie | 92 | 308 | 35 | 35 | 0 |
STRAP | STRAP | Q9Y3F4 | Serine-threonine kinase receptor-associated protein | chr12 | Not Cancer Driver | No | 3 | hippie, biogrid | 44 | 40 | 5 | 5 | 0 |
STT3A_ENST00000529196 | STT3A | P46977 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 82 | 27 | 2 | 2 | 1 |
SUPT5H | SUPT5H | O00267 | Transcription elongation factor SPT5 | chr19 | Not Cancer Driver | No | 1 | hippie | 165 | 572 | 87 | 87 | 0 |
SYNCRIP | SYNCRIP | O60506 | Heterogeneous nuclear ribonucleoprotein Q | chr6 | Not Cancer Driver | No | 1 | hippie | 93 | 285 | 39 | 39 | 0 |
TAX1BP1 | TAX1BP1 | Q86VP1 | Tax1-binding protein 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 78 | 429 | 50 | 50 | 0 |
TDRD3_ENST00000196169 | TDRD3 | Q9H7E2 | Tudor domain-containing protein 3 | chr13 | Not Cancer Driver | No | 1 | hippie | 97 | 518 | 77 | 77 | 0 |
TNFRSF10D | TNFRSF10D | Q9UBN6 | Tumor necrosis factor receptor superfamily member 10D | chr8 | Not Cancer Driver | No | 1 | hippie | 51 | 193 | 28 | 28 | 0 |
TNRC6B | TNRC6B | Q9UPQ9 | Trinucleotide repeat-containing gene 6B protein | chr22 | Not Cancer Driver | No | 1 | hippie | 205 | 1735 | 195 | 195 | 0 |
TOP3B_ENST00000357179 | TOP3B | O95985 | DNA topoisomerase 3-beta-1 | chr22 | Not Cancer Driver | No | 1 | hippie | 102 | 151 | 17 | 17 | 0 |
TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | Census, Compendium | Yes | 1 | hippie | 2891 | 282 | 1466 | 1466 | 83 |
TRAF6_ENST00000348124 | TRAF6 | Q9Y4K3 | TNF receptor-associated factor 6 | chr11 | Not Cancer Driver | No | 1 | hippie | 67 | 62 | 7 | 7 | 0 |
TRIM25 | TRIM25 | Q14258 | E3 ubiquitin/ISG15 ligase TRIM25 | chr17 | Not Cancer Driver | No | 1 | hippie | 59 | 225 | 20 | 20 | 0 |
TRMT1_ENST00000357720 | TRMT1 | Q9NXH9 | tRNA (guanine(26)-N(2))-dimethyltransferase | chr19 | Not Cancer Driver | No | 1 | hippie | 82 | 200 | 24 | 24 | 0 |
TUT4_ENST00000371544 | TUT4 | Q5TAX3 | Terminal uridylyltransferase 4 | chr1 | Not Cancer Driver | No | 1 | hippie | 187 | 771 | 102 | 102 | 0 |
UBE2I | UBE2I | P63279 | SUMO-conjugating enzyme UBC9 | chr16 | Not Cancer Driver | No | 1 | hippie | 16 | 16 | 3 | 3 | 0 |
UFL1 | UFL1 | O94874 | E3 UFM1-protein ligase 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 109 | 141 | 24 | 24 | 0 |
UGP2 | UGP2 | Q16851 | UTP--glucose-1-phosphate uridylyltransferase | chr2 | Not Cancer Driver | No | 1 | hippie | 65 | 55 | 7 | 7 | 1 |
UNK | UNK | Q9C0B0 | RING finger protein unkempt homolog | chr17 | Not Cancer Driver | No | 1 | hippie | 79 | 511 | 46 | 46 | 0 |
UPF1 | UPF1 | Q92900 | Regulator of nonsense transcripts 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 146 | 329 | 36 | 36 | 0 |
USP10_ENST00000219473 | USP10 | Q14694 | Ubiquitin carboxyl-terminal hydrolase 10 | chr16 | Not Cancer Driver | No | 1 | hippie | 92 | 425 | 49 | 49 | 0 |
VASN | VASN | Q6EMK4 | Vasorin | chr16 | Not Cancer Driver | No | 1 | hippie | 37 | 233 | 8 | 8 | 0 |
VIRMA | VIRMA | Q69YN4 | Protein virilizer homolog | chr8 | Not Cancer Driver | No | 1 | hippie | 211 | 631 | 93 | 93 | 0 |
WBP4 | WBP4 | O75554 | WW domain-binding protein 4 | chr13 | Not Cancer Driver | No | 1 | hippie | 44 | 309 | 37 | 37 | 0 |
WNK1_ENST00000315939 | WNK1 | Q9H4A3 | Serine/threonine-protein kinase WNK1 | chr12 | Not Cancer Driver | No | 1 | hippie | 278 | 1959 | 223 | 223 | 0 |
WWOX | WWOX | Q9NZC7 | WW domain-containing oxidoreductase | chr16 | Not Cancer Driver | No | 1 | hippie | 79 | 108 | 9 | 9 | 3 |
WWP2 | WWP2 | O00308 | NEDD4-like E3 ubiquitin-protein ligase WWP2 | chr16 | Not Cancer Driver | No | 1 | hippie | 112 | 422 | 57 | 57 | 0 |
XPO1_ENST00000406957 | XPO1 | O14980 | Exportin-1 | chr2 | Census, Compendium | Yes | 1 | hippie | 140 | 33 | 9 | 9 | 0 |
XRCC5_ENST00000392132 | XRCC5 | P13010 | X-ray repair cross-complementing protein 5 | chr2 | Not Cancer Driver | No | 1 | hippie | 87 | 118 | 11 | 11 | 0 |
XRCC6 | XRCC6 | P12956 | X-ray repair cross-complementing protein 6 | chr22 | Not Cancer Driver | No | 1 | hippie | 66 | 140 | 12 | 12 | 0 |
YBX1 | YBX1 | P67809 | Y-box-binding protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 41 | 312 | 41 | 41 | 0 |
YTHDF1 | YTHDF1 | Q9BYJ9 | YTH domain-containing family protein 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 87 | 369 | 46 | 46 | 0 |
YTHDF2_ENST00000542507 | YTHDF2 | Q9Y5A9 | YTH domain-containing family protein 2 | chr1 | Not Cancer Driver | No | 1 | hippie | 67 | 376 | 44 | 44 | 0 |
YTHDF3_ENST00000539294 | YTHDF3 | Q7Z739 | YTH domain-containing family protein 3 | chr8 | Not Cancer Driver | No | 1 | hippie | 74 | 409 | 51 | 51 | 0 |
ZC3H7A_ENST00000355758 | ZC3H7A | Q8IWR0 | Zinc finger CCCH domain-containing protein 7A | chr16 | Not Cancer Driver | No | 1 | hippie | 91 | 224 | 23 | 23 | 0 |
ZC3HAV1 | ZC3HAV1 | Q7Z2W4 | Zinc finger CCCH-type antiviral protein 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 142 | 344 | 63 | 63 | 0 |
ZCCHC3 | ZCCHC3 | Q9NUD5 | Zinc finger CCHC domain-containing protein 3 | chr20 | Not Cancer Driver | No | 1 | hippie | 28 | 160 | 1 | 1 | 0 |
ZNFX1_ENST00000371752 | ZNFX1 | Q9P2E3 | NFX1-type zinc finger-containing protein 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 228 | 354 | 49 | 49 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
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