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CRP ,CRP ,P02741
  • Number of Interaction partner in intact: 46
  • Number of Interaction partner in biogrid: 49
  • Number of Interaction partner in hippie: 83
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ADAM9 ADAM9 Q13443 Disintegrin and metalloproteinase domain-containing protein 9 chr8 Not Cancer Driver No 1 hippie, biogrid 86 129 13 13 0
AGPAT1 AGPAT1 Q99943 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha chr6 Not Cancer Driver No 1 hippie, biogrid 36 38 5 5 0
AGRN AGRN O00468 Agrin chr1 Not Cancer Driver No 2 intact, hippie, biogrid 188 490 40 40 5
ALB ALB P02768 Albumin chr4 Compendium Yes 2 intact 162 6 0 0 3
APCS APCS P02743 Serum amyloid P-component chr1 Not Cancer Driver No 1 hippie 73 0 0 0 0
B4GALT3_ENST00000367998 B4GALT3 O60512 Beta-1,4-galactosyltransferase 3 chr1 Not Cancer Driver No 2 hippie, biogrid 56 171 27 27 0
B4GALT4 B4GALT4 O60513 Beta-1,4-galactosyltransferase 4 chr3 Not Cancer Driver No 1 hippie, biogrid 49 14 4 4 0
B4GALT5 B4GALT5 O43286 Beta-1,4-galactosyltransferase 5 chr20 Not Cancer Driver No 2 hippie, biogrid 53 20 1 1 0
B4GALT7 B4GALT7 Q9UBV7 Beta-1,4-galactosyltransferase 7 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 32 44 6 6 2
C1GALT1_ENST00000223122 C1GALT1 Q9NS00 Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 chr7 Not Cancer Driver No 1 intact, hippie, biogrid 43 68 5 5 0
C1QA C1QA P02745 Complement C1q subcomponent subunit A chr1 Not Cancer Driver No 1 hippie 41 124 16 16 0
C3 C3 P01024 Complement C3 chr19 Not Cancer Driver No 1 intact, hippie 337 287 50 50 12
C4BPA C4BPA P04003 C4b-binding protein alpha chain chr1 Not Cancer Driver No 1 hippie 109 40 10 10 0
CA11 CA11 O75493 Carbonic anhydrase-related protein 11 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 50 46 5 5 0
CEMIP2 CEMIP2 Q9UHN6 Cell surface hyaluronidase chr9 Not Cancer Driver No 1 intact, hippie 198 229 26 26 0
CFH CFH P08603 Complement factor H chr1 Not Cancer Driver No 13 intact, hippie 355 89 28 28 42
CFHR1 CFHR1 Q03591 Complement factor H-related protein 1 chr1 Not Cancer Driver No 1 intact 68 42 11 11 0
CFHR3 CFHR3 Q02985 Complement factor H-related protein 3 chr1 Not Cancer Driver No 2 intact, hippie 87 12 5 5 0
CFHR4 CFHR4 Q92496 Complement factor H-related protein 4 chr1 Not Cancer Driver No 3 intact, hippie 192 11 4 4 0
CFHR5 CFHR5 Q9BXR6 Complement factor H-related protein 5 chr1 Not Cancer Driver No 1 intact, hippie 162 40 9 9 0
CFI_ENST00000394634 CFI P05156 Complement factor I chr4 Not Cancer Driver No 1 intact, hippie 97 4 0 0 13
CFP CFP P27918 Properdin chrX Not Cancer Driver No 1 intact, hippie 60 48 7 7 6
CHST12 CHST12 Q9NRB3 Carbohydrate sulfotransferase 12 chr7 Not Cancer Driver No 2 intact, hippie, biogrid 75 84 15 15 0
CHST14 CHST14 Q8NCH0 Carbohydrate sulfotransferase 14 chr15 Not Cancer Driver No 1 hippie, biogrid 23 78 2 2 6
CHST3 CHST3 Q7LGC8 Carbohydrate sulfotransferase 3 chr10 Not Cancer Driver No 2 intact, hippie, biogrid 49 55 4 4 5
CHST6_ENST00000390664 CHST6 Q9GZX3 Carbohydrate sulfotransferase 6 chr16 Not Cancer Driver No 1 hippie, biogrid 79 25 7 7 57
CNTNAP1 CNTNAP1 P78357 Contactin-associated protein 1 chr17 Not Cancer Driver No 1 hippie, biogrid 173 141 15 15 6
CNTNAP3 CNTNAP3 Q9BZ76 Contactin-associated protein-like 3 chr9 Not Cancer Driver No 2 intact, hippie, biogrid 181 216 14 14 0
CNTNAP3B CNTNAP3B Q96NU0 Contactin-associated protein-like 3B chr9 Not Cancer Driver No 1 hippie, biogrid 125 217 16 16 0
COL18A1 COL18A1 P39060 Collagen alpha-1(XVIII) chain chr21 Not Cancer Driver No 2 intact, hippie, biogrid 179 1284 142 142 0
COL4A2 COL4A2 P08572 Collagen alpha-2(IV) chain chr13 Not Cancer Driver No 1 intact, hippie, biogrid 264 1462 234 234 2
COLEC12 COLEC12 Q5KU26 Collectin-12 chr18 Not Cancer Driver No 1 intact 147 450 90 90 0
CRP CRP P02741 C-reactive protein chr1 Not Cancer Driver No 6 intact, hippie 59 0 0 0 0
CSPG4 CSPG4 Q6UVK1 Chondroitin sulfate proteoglycan 4 chr15 Not Cancer Driver No 1 hippie, biogrid 259 838 85 85 0
ESS2 ESS2 Q96DF8 Splicing factor ESS-2 homolog chr22 Not Cancer Driver No 1 intact, hippie 71 458 68 68 0
EXT1 EXT1 Q16394 Exostosin-1 chr8 Census Yes 2 hippie, biogrid 107 58 7 7 12
FCGR1A FCGR1A P12314 High affinity immunoglobulin gamma Fc receptor I chr1 Not Cancer Driver No 1 hippie 62 37 5 5 0
FCGR2A FCGR2A P12318 Low affinity immunoglobulin gamma Fc region receptor II-a chr1 Not Cancer Driver No 2 intact, hippie 64 133 28 28 0
FCGR2B FCGR2B P31994 Low affinity immunoglobulin gamma Fc region receptor II-b chr1 Census Yes 1 hippie 51 99 30 30 0
FCGR2C FCGR2C P31995 Low affinity immunoglobulin gamma Fc region receptor II-c chr1 Not Cancer Driver No 1 intact, hippie 40 121 24 24 0
FCN1 FCN1 O00602 Ficolin-1 chr9 Not Cancer Driver No 1 intact, hippie 107 88 15 15 0
FCN2 FCN2 Q15485 Ficolin-2 chr9 Not Cancer Driver No 1 intact, hippie 73 80 19 19 0
FFAR2 FFAR2 O15552 Free fatty acid receptor 2 chr19 Not Cancer Driver No 1 intact, hippie 49 32 7 7 0
FN1 FN1 P02751 Fibronectin chr2 Compendium Yes 1 hippie 394 1243 185 185 8
GDF11 GDF11 O95390 Growth/differentiation factor 11 chr12 Not Cancer Driver No 2 intact, hippie, biogrid 40 109 7 7 1
GLUD1 GLUD1 P00367 Glutamate dehydrogenase 1, mitochondrial chr10 Not Cancer Driver No 1 intact, hippie 50 107 14 14 13
GMPPA_ENST00000313597 GMPPA Q96IJ6 Mannose-1-phosphate guanyltransferase alpha chr2 Not Cancer Driver No 1 intact, hippie 53 59 16 16 5
GP6_ENST00000417454 GP6 Q9HCN6 Platelet glycoprotein VI chr19 Not Cancer Driver No 1 hippie 57 122 21 21 2
HS3ST1 HS3ST1 O14792 Heparan sulfate glucosamine 3-O-sulfotransferase 1 chr4 Not Cancer Driver No 1 hippie, biogrid 71 39 7 7 0
HS6ST1 HS6ST1 O60243 Heparan-sulfate 6-O-sulfotransferase 1 chr2 Not Cancer Driver No 2 intact, hippie, biogrid 60 66 14 14 6
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 Not Cancer Driver No 1 intact, hippie 73 282 35 35 0
IDUA IDUA P35475 Alpha-L-iduronidase chr4 Not Cancer Driver No 1 hippie, biogrid 46 101 5 5 57
IMPAD1 BPNT2 Q9NX62 Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase chr8 Not Cancer Driver No 1 intact 45 86 10 10 2
LACTB LACTB P83111 Serine beta-lactamase-like protein LACTB, mitochondrial chr15 Not Cancer Driver No 1 hippie, biogrid 44 121 3 3 0
LAMA1 LAMA1 P25391 Laminin subunit alpha-1 chr18 Not Cancer Driver No 2 hippie, biogrid 600 329 71 71 0
LAMA5 LAMA5 O15230 Laminin subunit alpha-5 chr20 Not Cancer Driver No 2 intact, hippie, biogrid 431 701 90 90 0
LAMB1 LAMB1 P07942 Laminin subunit beta-1 chr7 Not Cancer Driver No 2 intact, hippie, biogrid 240 418 50 50 0
LAMB2 LAMB2 P55268 Laminin subunit beta-2 chr3 Not Cancer Driver No 2 hippie, biogrid 234 463 67 67 9
LAMC1 LAMC1 P11047 Laminin subunit gamma-1 chr1 Not Cancer Driver No 1 hippie, biogrid 232 562 94 94 0
LAMC3 LAMC3 Q9Y6N6 Laminin subunit gamma-3 chr9 Not Cancer Driver No 1 hippie 243 422 49 49 1
LEP LEP P41159 Leptin chr7 Not Cancer Driver No 1 hippie 29 0 0 0 2
LRRC24 LRRC24 Q50LG9 Leucine-rich repeat-containing protein 24 chr8 Not Cancer Driver No 1 hippie, biogrid 32 131 13 13 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 Census, Compendium Yes 1 intact, hippie 62 2 0 0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 Not Cancer Driver No 1 hippie 38 49 5 5 0
MAPK8IP2 MAPK8IP2 Q13387 C-Jun-amino-terminal kinase-interacting protein 2 chr22 Not Cancer Driver No 1 hippie 49 568 27 27 0
NDST2 NDST2 P52849 Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 chr10 Not Cancer Driver No 1 intact, hippie, biogrid 95 60 7 7 0
NXPE3_ENST00000273347 NXPE3 Q969Y0 NXPE family member 3 chr3 Not Cancer Driver No 2 hippie, biogrid 80 0 0 0 0
PDF PDF Q9HBH1 Peptide deformylase, mitochondrial chr16 Not Cancer Driver No 2 intact, hippie, biogrid 7 8 0 0 0
PDIA5 PDIA5 Q14554 Protein disulfide-isomerase A5 chr3 Not Cancer Driver No 1 hippie, biogrid 73 79 9 9 0
PRSS23 PRSS23 O95084 Serine protease 23 chr11 Not Cancer Driver No 2 hippie, biogrid 53 51 4 4 0
PTPRS PTPRS Q13332 Receptor-type tyrosine-protein phosphatase S chr19 Not Cancer Driver No 2 intact, hippie, biogrid 250 829 111 111 0
PTX3 PTX3 P26022 Pentraxin-related protein PTX3 chr3 Not Cancer Driver No 1 hippie 39 74 2 2 0
QSOX1 QSOX1 O00391 Sulfhydryl oxidase 1 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 93 189 22 22 0
RPL13A RPL13A P40429 60S ribosomal protein L13a chr19 Not Cancer Driver No 1 hippie 27 33 2 2 0
RPL23_ENST00000394332 RPL23 P62829 60S ribosomal protein L23 chr17 Not Cancer Driver No 1 intact, hippie, biogrid 14 29 4 4 0
RPL26L1 RPL26L1 Q9UNX3 60S ribosomal protein L26-like 1 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 21 107 11 11 0
SNRNP70 SNRNP70 P08621 U1 small nuclear ribonucleoprotein 70 kDa chr19 Not Cancer Driver No 1 hippie 38 416 37 37 0
SPTB_ENST00000389721 SPTB P11277 Spectrin beta chain, erythrocytic chr14 Not Cancer Driver No 2 hippie, biogrid 328 562 70 70 7
ST3GAL4_ENST00000534083 ST3GAL4 Q11206 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 31 3 2 2 0
ST8SIA6 ST8SIA6 P61647 Alpha-2,8-sialyltransferase 8F chr10 Not Cancer Driver No 1 hippie, biogrid 71 45 7 7 0
STC2 STC2 O76061 Stanniocalcin-2 chr5 Not Cancer Driver No 2 hippie, biogrid 71 112 29 29 0
STRBP_ENST00000348403 STRBP Q96SI9 Spermatid perinuclear RNA-binding protein chr9 Not Cancer Driver No 1 intact, hippie, biogrid 74 306 31 31 0
TIMP3 TIMP3 P35625 Metalloproteinase inhibitor 3 chr22 Not Cancer Driver No 2 intact, hippie, biogrid 43 3 1 1 5
TMEM59 TMEM59 Q9BXS4 Transmembrane protein 59 chr1 Not Cancer Driver No 1 hippie, biogrid 39 26 3 3 0
UBE3A UBE3A Q05086 Ubiquitin-protein ligase E3A chr15 Not Cancer Driver No 1 hippie 141 136 22 22 0
UBR3 UBR3 Q6ZT12 E3 ubiquitin-protein ligase UBR3 chr2 Not Cancer Driver No 2 intact, hippie, biogrid 154 339 28 28 0
VGF VGF O15240 Neurosecretory protein VGF chr7 Not Cancer Driver No 1 hippie, biogrid 48 593 47 47 0