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CROCC ,CROCC ,Q5TZA2
  • Uniprot Accession= Q5TZA2
  • Ensembl Transcript= ENST00000375541.9
  • Uniprot Name= CROCC
  • Name= Rootletin
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 19
  • Number of Interaction partner in biogrid: 18
  • Number of Interaction partner in hippie: 42
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
BMI1 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 1 intact, hippie 50 150 30 30 0
BRD2_ENST00000374831 BRD2 P25440 Bromodomain-containing protein 2 chr6 Not Cancer Driver No 1 hippie 108 632 85 85 0
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 193 1182 172 172 0
BRDT_ENST00000362005 BRDT Q58F21 Bromodomain testis-specific protein chr1 Not Cancer Driver No 1 hippie 173 703 121 121 0
CEP152 CEP152 O94986 Centrosomal protein of 152 kDa chr15 Not Cancer Driver No 1 intact, hippie 204 986 110 110 2
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 Not Cancer Driver No 1 hippie 118 61 10 10 2
EPS15L1_ENST00000248070 EPS15L1 Q9UBC2 Epidermal growth factor receptor substrate 15-like 1 chr19 Not Cancer Driver No 1 hippie, biogrid 109 603 76 76 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 121 195 27 27 2
EZR EZR P15311 Ezrin chr6 Census Yes 1 hippie 66 295 35 35 0
G3BP1 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 Not Cancer Driver No 1 intact, hippie 85 352 65 65 0
GAN GAN Q9H2C0 Gigaxonin chr16 Not Cancer Driver No 1 hippie 74 33 6 6 19
GAPDH GAPDH P04406 Glyceraldehyde-3-phosphate dehydrogenase chr12 Not Cancer Driver No 1 intact, hippie 39 24 3 3 0
GIT1_ENST00000225394 GIT1 Q9Y2X7 ARF GTPase-activating protein GIT1 chr17 Not Cancer Driver No 1 intact, hippie, biogrid 67 434 42 42 0
GRK2 GRK2 P25098 Beta-adrenergic receptor kinase 1 chr11 Not Cancer Driver No 1 hippie 77 87 8 8 0
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 Not Cancer Driver No 1 intact, hippie 47 135 10 10 0
HDAC8 HDAC8 Q9BY41 Histone deacetylase 8 chrX Not Cancer Driver No 1 intact, hippie, biogrid 54 32 4 4 4
HDGF_ENST00000357325 HDGF P51858 Hepatoma-derived growth factor chr1 Not Cancer Driver No 1 hippie 35 203 29 29 0
HIST1H2BH H2BC9 Q93079 Histone H2B type 1-H chr6 Not Cancer Driver No 1 intact 42 79 20 20 0
HNRNPL HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 89 283 29 29 0
KLC3 KLC3 Q6P597 Kinesin light chain 3 chr19 Not Cancer Driver No 1 hippie 52 338 32 32 0
KRT222 KRT222 Q8N1A0 Keratin-like protein KRT222 chr17 Not Cancer Driver No 1 hippie, biogrid 51 132 18 18 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
OPTN_ENST00000263036 OPTN Q96CV9 Optineurin chr10 Not Cancer Driver No 1 hippie 58 470 51 51 6
PEX14 PEX14 O75381 Peroxisomal membrane protein PEX14 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 38 266 28 28 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 Not Cancer Driver No 1 hippie 72 124 17 17 0
PTBP3_ENST00000374255 PTBP3 O95758 Polypyrimidine tract-binding protein 3 chr9 Not Cancer Driver No 1 intact, hippie 61 114 9 9 0
PUSL1 PUSL1 Q8N0Z8 tRNA pseudouridine synthase-like 1 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 15 76 1 1 0
RALBP1 RALBP1 Q15311 RalA-binding protein 1 chr18 Not Cancer Driver No 2 hippie, biogrid 65 381 46 46 0
RNF152 RNF152 Q8N8N0 E3 ubiquitin-protein ligase RNF152 chr18 Not Cancer Driver No 1 intact, hippie 61 34 11 11 0
RYBP RYBP Q8N488 RING1 and YY1-binding protein chr3 Not Cancer Driver No 1 hippie 37 214 37 37 0
SCGN SCGN O76038 Secretagogin chr6 Not Cancer Driver No 3 intact, hippie, biogrid 77 12 1 1 0
SCOC SCOC Q9UIL1 Short coiled-coil protein chr4 Not Cancer Driver No 1 intact, hippie, biogrid 13 82 8 8 0
SRBD1 SRBD1 Q8N5C6 S1 RNA-binding domain-containing protein 1 chr2 Not Cancer Driver No 1 intact, hippie, biogrid 110 279 29 29 0
SYCE1_ENST00000343131 SYCE1 Q8N0S2 Synaptonemal complex central element protein 1 chr10 Not Cancer Driver No 1 hippie, biogrid 70 251 50 50 0
SYNE1 SYNE1 Q8NF91 Nesprin-1 chr6 Not Cancer Driver No 1 hippie 1694 2530 530 530 2
TGFBRAP1 TGFBRAP1 Q8WUH2 Transforming growth factor-beta receptor-associated protein 1 chr2 Not Cancer Driver No 1 intact, hippie, biogrid 127 37 8 8 0
TPM1_ENST00000403994 TPM1 P09493 Tropomyosin alpha-1 chain chr15 Not Cancer Driver No 3 hippie, biogrid 33 234 29 29 8
TPM3 TPM3 P06753 Tropomyosin alpha-3 chain chr1 Census Yes 1 hippie, biogrid 35 230 27 27 21
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
UBR1 UBR1 Q8IWV7 E3 ubiquitin-protein ligase UBR1 chr15 Not Cancer Driver No 1 hippie, biogrid 170 165 15 15 18
UBR2 UBR2 Q8IWV8 E3 ubiquitin-protein ligase UBR2 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 172 228 30 30 0
XBP1 XBP1 P17861 X-box-binding protein 1 chr22 Not Cancer Driver No 1 hippie, biogrid 19 169 9 9 0
ZYG11B ZYG11B Q9C0D3 Protein zyg-11 homolog B chr1 Not Cancer Driver No 1 intact, hippie, biogrid 88 30 7 7 0