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COL2A1 ,COL2A1 ,P02458
  • Uniprot Accession= P02458
  • Ensembl Transcript= ENST00000380518.7
  • Uniprot Name= COL2A1
  • Name= Collagen alpha-1(II) chain
  • Chromosome= chr12
  • Driver status= Census
  • Number of Interaction partner in intact: 19
  • Number of Interaction partner in biogrid: 20
  • Number of Interaction partner in hippie: 69
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
AGR2 AGR2 O95994 Anterior gradient protein 2 homolog chr7 Not Cancer Driver No 1 hippie 23 20 2 2 0
ANXA5 ANXA5 P08758 Annexin A5 chr4 Not Cancer Driver No 1 hippie 50 33 5 5 0
BGN BGN P21810 Biglycan chrX Not Cancer Driver No 1 hippie 63 26 3 3 2
BMP2 BMP2 P12643 Bone morphogenetic protein 2 chr20 Not Cancer Driver No 1 hippie 73 139 26 26 0
C1QA C1QA P02745 Complement C1q subcomponent subunit A chr1 Not Cancer Driver No 1 hippie 41 124 16 16 0
C1QC C1QC P02747 Complement C1q subcomponent subunit C chr1 Not Cancer Driver No 1 hippie, biogrid 46 134 26 26 1
C1QTNF1_ENST00000581774 C1QTNF1 Q9BXJ1 Complement C1q tumor necrosis factor-related protein 1 chr17 Not Cancer Driver No 1 hippie, biogrid 61 96 17 17 0
C1QTNF2 C1QTNF2 A0A499FIM1 C1q and tumor necrosis factor related protein 2 chr5 Not Cancer Driver No 3 intact, hippie, biogrid 58 169 38 38 0
C1QTNF9B C1QTNF9B B2RNN3 Complement C1q and tumor necrosis factor-related protein 9B chr13 Not Cancer Driver No 1 hippie, biogrid 62 183 43 43 0
C1QTNF9_ENST00000332018 C1QTNF9 P0C862 Complement C1q and tumor necrosis factor-related protein 9A chr13 Not Cancer Driver No 3 hippie, biogrid 70 183 43 43 0
CASP6 CASP6 P55212 Caspase-6 chr4 Not Cancer Driver No 1 hippie 28 24 4 4 0
CHAD_ENST00000258969 CHAD O15335 Chondroadherin chr17 Not Cancer Driver No 1 hippie 51 22 3 3 0
CHODL CHODL Q9H9P2 Chondrolectin chr21 Not Cancer Driver No 1 hippie, biogrid 50 45 7 7 0
CNPY2 CNPY2 Q9Y2B0 Protein canopy homolog 2 chr12 Not Cancer Driver No 2 hippie, biogrid 24 24 3 3 0
COCH_ENST00000643575 COCH O43405 Cochlin chr14 Not Cancer Driver No 1 intact, hippie 81 43 6 6 14
COL11A1 COL11A1 P12107 Collagen alpha-1(XI) chain chr1 Not Cancer Driver No 1 hippie 749 1436 617 617 8
COL11A2_ENST00000341947 COL11A2 P13942 Collagen alpha-2(XI) chain chr6 Not Cancer Driver No 1 hippie 286 1471 246 246 7
COL1A1 COL1A1 P02452 Collagen alpha-1(I) chain chr17 Census, Compendium Yes 1 hippie 247 1212 214 214 148
COL2A1 COL2A1 P02458 Collagen alpha-1(II) chain chr12 Census Yes 1 hippie 258 1215 207 207 64
COL6A1 COL6A1 P12109 Collagen alpha-1(VI) chain chr21 Not Cancer Driver No 1 hippie 145 434 61 61 12
COL8A1_ENST00000273342 COL8A1 P27658 Collagen alpha-1(VIII) chain chr3 Not Cancer Driver No 1 hippie, biogrid 156 586 133 133 0
COL8A2_ENST00000303143 COL8A2 P25067 Collagen alpha-2(VIII) chain chr1 Not Cancer Driver No 3 intact, hippie, biogrid 75 559 58 58 4
COL9A1 COL9A1 P20849 Collagen alpha-1(IX) chain chr6 Not Cancer Driver No 4 intact, hippie, biogrid 262 722 201 201 0
COL9A2 COL9A2 Q14055 Collagen alpha-2(IX) chain chr1 Not Cancer Driver No 1 hippie 113 687 113 113 1
COL9A3 COL9A3 Q14050 Collagen alpha-3(IX) chain chr20 Not Cancer Driver No 1 hippie 118 684 118 118 1
COLGALT2 COLGALT2 Q8IYK4 Procollagen galactosyltransferase 2 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 101 75 4 4 0
COMP COMP P49747 Cartilage oligomeric matrix protein chr19 Not Cancer Driver No 1 hippie 97 306 52 52 61
COQ8A COQ8A Q8NI60 Atypical kinase COQ8A, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 95 166 29 29 12
DCN DCN P07585 Decorin chr12 Not Cancer Driver No 1 hippie 96 81 26 26 0
DDR1_ENST00000324771 DDR1 Q08345 Epithelial discoidin domain-containing receptor 1 chr6 Not Cancer Driver No 1 hippie 123 253 49 49 0
FGF7 FGF7 P21781 Fibroblast growth factor 7 chr15 Not Cancer Driver No 1 hippie 38 22 4 4 0
FGFR3_ENST00000440486 FGFR3 P22607 Fibroblast growth factor receptor 3 chr4 Census, Compendium Yes 1 intact, hippie 173 241 26 26 37
FKBP9_ENST00000242209 FKBP9 O95302 Peptidyl-prolyl cis-trans isomerase FKBP9 chr7 Census Yes 2 intact, hippie, biogrid 155 40 10 10 0
FN1 FN1 P02751 Fibronectin chr2 Compendium Yes 1 hippie 394 1243 185 185 8
GRIN2C GRIN2C Q14957 Glutamate receptor ionotropic, NMDA 2C chr17 Not Cancer Driver No 1 intact, hippie 111 276 6 6 0
GSN GSN P06396 Gelsolin chr9 Not Cancer Driver No 1 intact, hippie 76 316 28 28 2
HIP1 HIP1 O00291 Huntingtin-interacting protein 1 chr7 Census, Compendium Yes 1 intact, hippie 137 510 70 70 0
HTRA1 HTRA1 Q92743 Serine protease HTRA1 chr10 Not Cancer Driver No 1 hippie 77 40 9 9 11
HYAL1_ENST00000395144 HYAL1 Q12794 Hyaluronidase-1 chr3 Not Cancer Driver No 1 intact, hippie 47 9 0 0 1
ITGA2B ITGA2B P08514 Integrin alpha-IIb chr17 Not Cancer Driver No 1 hippie 133 188 31 31 34
KEAP1_ENST00000393623 KEAP1 Q14145 Kelch-like ECH-associated protein 1 chr19 Census, Compendium Yes 1 hippie 237 57 12 12 0
LAIR2 LAIR2 Q6ISS4 Leukocyte-associated immunoglobulin-like receptor 2 chr19 Not Cancer Driver No 1 hippie, biogrid 46 77 26 26 0
LAMP2_ENST00000200639 LAMP2 P13473 Lysosome-associated membrane glycoprotein 2 chrX Not Cancer Driver No 1 intact, hippie 43 55 7 7 1
LOXL4 LOXL4 Q96JB6 Lysyl oxidase homolog 4 chr10 Not Cancer Driver No 1 hippie 95 122 11 11 0
MAG_ENST00000537831 MAG P20916 Myelin-associated glycoprotein chr19 Not Cancer Driver No 1 hippie 118 65 7 7 1
MATN1 MATN1 P21941 Cartilage matrix protein chr1 Not Cancer Driver No 2 intact, hippie 49 18 2 2 0
MMP1 MMP1 P03956 Interstitial collagenase chr11 Not Cancer Driver No 1 hippie 83 113 18 18 0
MMP13 MMP13 P45452 Collagenase 3 chr11 Not Cancer Driver No 1 hippie 113 59 16 16 5
MMP2 MMP2 P08253 72 kDa type IV collagenase chr16 Not Cancer Driver No 2 intact, hippie, biogrid 123 29 6 6 2
MMP9 MMP9 P14780 Matrix metalloproteinase-9 chr20 Not Cancer Driver No 2 intact, hippie, biogrid 129 124 26 26 0
NXPH2 NXPH2 O95156 Neurexophilin-2 chr2 Not Cancer Driver No 1 hippie, biogrid 80 8 2 2 0
OSCAR_ENST00000284648 OSCAR Q8IYS5 Osteoclast-associated immunoglobulin-like receptor chr19 Not Cancer Driver No 1 hippie, biogrid 29 69 4 4 0
P4HA1_ENST00000394890 P4HA1 P13674 Prolyl 4-hydroxylase subunit alpha-1 chr10 Not Cancer Driver No 1 hippie, biogrid 65 54 8 8 0
PCOLCE PCOLCE Q15113 Procollagen C-endopeptidase enhancer 1 chr7 Not Cancer Driver No 1 hippie 46 187 18 18 0
PDGFA PDGFA P04085 Platelet-derived growth factor subunit A chr7 Not Cancer Driver No 1 hippie 31 75 10 10 0
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 Census Yes 1 hippie 37 99 22 22 2
PDIA2 PDIA2 Q13087 Protein disulfide-isomerase A2 chr16 Not Cancer Driver No 1 hippie 70 80 12 12 0
PKD1 PKD1 P98161 Polycystin-1 chr16 Not Cancer Driver No 1 hippie 393 690 66 66 92
PLOD1 PLOD1 Q02809 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 chr1 Not Cancer Driver No 2 hippie, biogrid 86 12 0 0 5
PRELP PRELP P51888 Prolargin chr1 Not Cancer Driver No 1 hippie 63 55 13 13 0
PRPF40A PRPF40A O75400 Pre-mRNA-processing factor 40 homolog A chr2 Not Cancer Driver No 1 intact, hippie 83 694 57 57 0
RELA RELA Q04206 Transcription factor p65 chr11 Compendium Yes 1 hippie 75 400 48 48 0
RPL36AL RPL36AL Q969Q0 60S ribosomal protein L36a-like chr14 Not Cancer Driver No 1 hippie, biogrid 9 64 7 7 0
SPARC SPARC P09486 SPARC chr5 Not Cancer Driver No 1 hippie 60 69 5 5 2
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 Not Cancer Driver No 1 hippie 41 41 4 4 10
TGFBI TGFBI Q15582 Transforming growth factor-beta-induced protein ig-h3 chr5 Not Cancer Driver No 1 hippie 108 58 19 19 23
THBS1 THBS1 P07996 Thrombospondin-1 chr15 Not Cancer Driver No 1 hippie 188 320 58 58 0
TNFRSF10A TNFRSF10A O00220 Tumor necrosis factor receptor superfamily member 10A chr8 Not Cancer Driver No 1 hippie 55 174 17 17 0
UBQLN1 UBQLN1 Q9UMX0 Ubiquilin-1 chr9 Not Cancer Driver No 1 hippie 64 543 58 58 0