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COA7 ,COA7 ,Q96BR5
  • Uniprot Accession= Q96BR5
  • Ensembl Transcript= ENST00000371538.4
  • Uniprot Name= COA7
  • Name= Cytochrome c oxidase assembly factor 7
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 32
  • Number of Interaction partner in biogrid: 69
  • Number of Interaction partner in hippie: 114
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
ACO2 ACO2 Q99798 Aconitate hydratase, mitochondrial chr22 Not Cancer Driver No 1 hippie, biogrid 94 172 19 19 5
ACOT8 ACOT8 O14734 Acyl-coenzyme A thioesterase 8 chr20 Not Cancer Driver No 1 hippie, biogrid 43 52 7 7 0
ACP5_ENST00000433365 ACP5 P13686 Tartrate-resistant acid phosphatase type 5 chr19 Not Cancer Driver No 1 hippie 51 31 6 6 8
AES_ENST00000327141 TLE5 Q08117 TLE family member 5 chr19 Not Cancer Driver No 1 intact 16 77 7 7 0
AIFM1 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX Not Cancer Driver No 2 intact, hippie, biogrid 88 166 22 22 11
APOO APOO Q9BUR5 MICOS complex subunit MIC26 chrX Not Cancer Driver No 1 hippie, biogrid 25 23 4 4 0
ATXN3 ATXN3 P54252 Ataxin-3 chr14 Not Cancer Driver No 1 hippie 46 181 24 24 0
B3GNT3_ENST00000595387 B3GNT3 Q9Y2A9 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3 chr19 Not Cancer Driver No 1 hippie, biogrid 69 44 6 6 0
B3GNT7 B3GNT7 Q8NFL0 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 chr2 Not Cancer Driver No 1 hippie, biogrid 53 73 10 10 0
B4GALT3_ENST00000367998 B4GALT3 O60512 Beta-1,4-galactosyltransferase 3 chr1 Not Cancer Driver No 1 hippie, biogrid 56 171 27 27 0
C11orf54_ENST00000354421 C11orf54 Q9H0W9 Ester hydrolase C11orf54 chr11 Not Cancer Driver No 1 hippie, biogrid 23 23 0 0 0
CASP6 CASP6 P55212 Caspase-6 chr4 Not Cancer Driver No 1 hippie 28 24 4 4 0
CCN2 CCN2 P29279 CCN family member 2 chr6 Not Cancer Driver No 1 intact, hippie 58 0 0 0 0
CHCHD4_ENST00000396914 CHCHD4 Q8N4Q1 Mitochondrial intermembrane space import and assembly protein 40 chr3 Not Cancer Driver No 2 hippie, biogrid 18 82 8 8 0
CKMT2_ENST00000437669 CKMT2 P17540 Creatine kinase S-type, mitochondrial chr5 Not Cancer Driver No 1 hippie, biogrid 70 68 12 12 0
CLIC4 CLIC4 Q9Y696 Chloride intracellular channel protein 4 chr1 Not Cancer Driver No 1 hippie, biogrid 24 49 4 4 0
CLPB CLPB Q9H078 Caseinolytic peptidase B protein homolog chr11 Not Cancer Driver No 1 hippie, biogrid 69 224 25 25 11
COX11 COX11 Q9Y6N1 Cytochrome c oxidase assembly protein COX11, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 21 51 4 4 0
COX14_ENST00000550654 COX14 Q96I36 Cytochrome c oxidase assembly protein COX14 chr12 Not Cancer Driver No 1 intact, hippie 4 7 0 0 1
COX15 COX15 Q7KZN9 Cytochrome c oxidase assembly protein COX15 homolog chr10 Not Cancer Driver No 1 hippie, biogrid 48 0 0 0 2
COX4I1 COX4I1 P13073 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial chr16 Not Cancer Driver No 3 intact, hippie, biogrid 17 5 1 1 1
COX6B1_ENST00000592141 COX6B1 P14854 Cytochrome c oxidase subunit 6B1 chr19 Not Cancer Driver No 1 intact, hippie 15 23 6 6 2
CRHBP CRHBP P24387 Corticotropin-releasing factor-binding protein chr5 Not Cancer Driver No 3 hippie, biogrid 61 0 0 0 0
CYCS_ENST00000409409 CYCS P99999 Cytochrome c chr7 Not Cancer Driver No 1 intact, hippie 12 19 3 3 1
DDI2 DDI2 Q5TDH0 Protein DDI1 homolog 2 chr1 Not Cancer Driver No 1 hippie, biogrid 47 187 30 30 0
DIABLO DIABLO Q9NR28 Diablo IAP-binding mitochondrial protein chr12 Not Cancer Driver No 1 hippie, biogrid 62 54 8 8 1
DMWD DMWD Q09019 Dystrophia myotonica WD repeat-containing protein chr19 Not Cancer Driver No 1 intact 66 374 24 24 0
DNAJC30 DNAJC30 Q96LL9 DnaJ homolog subfamily C member 30, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 25 83 7 7 3
DNAJC4_ENST00000321685 DNAJC4 Q9NNZ3 DnaJ homolog subfamily C member 4 chr11 Not Cancer Driver No 1 hippie, biogrid 19 180 13 13 0
DPP8_ENST00000559233 DPP8 Q6V1X1 Dipeptidyl peptidase 8 chr15 Not Cancer Driver No 1 hippie, biogrid 99 71 5 5 0
DUSP4 DUSP4 Q13115 Dual specificity protein phosphatase 4 chr8 Not Cancer Driver No 1 hippie 43 63 9 9 0
EFHC1 EFHC1 Q5JVL4 EF-hand domain-containing protein 1 chr6 Not Cancer Driver No 2 intact, hippie 79 78 15 15 17
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
ENKD1 ENKD1 Q9H0I2 Enkurin domain-containing protein 1 chr16 Not Cancer Driver No 1 intact, hippie 40 307 34 34 0
ETHE1 ETHE1 O95571 Persulfide dioxygenase ETHE1, mitochondrial chr19 Not Cancer Driver No 1 hippie, biogrid 21 6 0 0 9
FAM219B_ENST00000563119 FAM219B Q5XKK7 Protein FAM219B chr15 Not Cancer Driver No 1 hippie, biogrid 11 174 11 11 0
FBXO34 FBXO34 Q9NWN3 F-box only protein 34 chr14 Not Cancer Driver No 1 intact, hippie 90 421 55 55 0
FDX1 FDX1 P10109 Adrenodoxin, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 12 61 2 2 0
FDX2 FDX2 Q6P4F2 Ferredoxin-2, mitochondrial chr19 Not Cancer Driver No 1 hippie 26 102 14 14 1
FGFR3_ENST00000440486 FGFR3 P22607 Fibroblast growth factor receptor 3 chr4 Census, Compendium Yes 1 intact, hippie 173 241 26 26 37
FKBP10 FKBP10 Q96AY3 Peptidyl-prolyl cis-trans isomerase FKBP10 chr17 Not Cancer Driver No 1 hippie, biogrid 60 134 8 8 3
FMC1 FMC1 Q96HJ9 Protein FMC1 homolog chr7 Not Cancer Driver No 1 intact, hippie 9 30 1 1 0
FNBP1L FNBP1L Q5T0N5 Formin-binding protein 1-like chr1 Not Cancer Driver No 1 hippie, biogrid 56 371 30 30 0
FXN FXN Q16595 Frataxin, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 16 73 0 0 8
GCSH GCSH P23434 Glycine cleavage system H protein, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 15 25 0 0 0
GLOD4_ENST00000301328 GLOD4 Q9HC38 Glyoxalase domain-containing protein 4 chr17 Not Cancer Driver No 1 hippie, biogrid 34 44 3 3 0
GPSM3_ENST00000375043 GPSM3 Q9Y4H4 G-protein-signaling modulator 3 chr6 Not Cancer Driver No 1 hippie 26 160 26 26 0
GRHPR GRHPR Q9UBQ7 Glyoxylate reductase/hydroxypyruvate reductase chr9 Not Cancer Driver No 1 hippie, biogrid 31 36 4 4 0
GSN GSN P06396 Gelsolin chr9 Not Cancer Driver No 1 intact, hippie 76 316 28 28 2
GUK1_ENST00000366718 GUK1 Q16774 Guanylate kinase chr1 Not Cancer Driver No 1 hippie, biogrid 28 71 9 9 0
HMOX2_ENST00000406590 HMOX2 P30519 Heme oxygenase 2 chr16 Not Cancer Driver No 1 intact, hippie 27 74 10 10 0
HOXB1 HOXB1 P14653 Homeobox protein Hox-B1 chr17 Not Cancer Driver No 1 hippie, biogrid 71 276 68 68 1
HSPB2 HSPB2 Q16082 Heat shock protein beta-2 chr11 Not Cancer Driver No 1 hippie, biogrid 25 103 11 11 0
HTRA2 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 Compendium Yes 1 hippie 44 127 9 9 2
IDH2 IDH2 P48735 Isocitrate dehydrogenase [NADP], mitochondrial chr15 Census, Compendium Yes 1 hippie, biogrid 74 59 1 1 7
IGF2R IGF2R P11717 Cation-independent mannose-6-phosphate receptor chr6 Not Cancer Driver No 1 hippie, biogrid 318 255 20 20 0
IMMP1L IMMP1L Q96LU5 Mitochondrial inner membrane protease subunit 1 chr11 Not Cancer Driver No 1 hippie 20 3 0 0 0
IMMP2L_ENST00000452895 IMMP2L Q96T52 Mitochondrial inner membrane protease subunit 2 chr7 Not Cancer Driver No 1 hippie 36 29 7 7 0
ISCA2 ISCA2 Q86U28 Iron-sulfur cluster assembly 2 homolog, mitochondrial chr14 Not Cancer Driver No 1 hippie, biogrid 13 38 3 3 1
LACTB LACTB P83111 Serine beta-lactamase-like protein LACTB, mitochondrial chr15 Not Cancer Driver No 1 intact, hippie 44 121 3 3 0
LACTB2 LACTB2 Q53H82 Endoribonuclease LACTB2 chr8 Not Cancer Driver No 1 hippie, biogrid 34 21 1 1 0
LAMP2_ENST00000200639 LAMP2 P13473 Lysosome-associated membrane glycoprotein 2 chrX Not Cancer Driver No 1 intact, hippie 43 55 7 7 1
LAP3 LAP3 P28838 Cytosol aminopeptidase chr4 Not Cancer Driver No 1 hippie, biogrid 59 99 14 14 0
LIG4 LIG4 P49917 DNA ligase 4 chr13 Not Cancer Driver No 1 hippie 134 63 10 10 2
MAP4K3 MAP4K3 Q8IVH8 Mitogen-activated protein kinase kinase kinase kinase 3 chr2 Not Cancer Driver No 1 hippie 116 313 45 45 0
MDC1 MDC1 Q14676 Mediator of DNA damage checkpoint protein 1 chr6 Not Cancer Driver No 1 hippie 249 1829 223 223 0
MINOS1 MICOS10 Q5TGZ0 MICOS complex subunit MIC10 chr1 Not Cancer Driver No 1 hippie 5 0 0 0 0
MPLKIP_ENST00000645701 MPLKIP Q8TAP9 M-phase-specific PLK1-interacting protein chr7 Not Cancer Driver No 1 hippie, biogrid 13 175 13 13 1
MPPED1_ENST00000443721 MPPED1 O15442 Metallophosphoesterase domain-containing protein 1 chr22 Not Cancer Driver No 1 hippie, biogrid 79 26 15 15 0
MSRB3 MSRB3 Q8IXL7 Methionine-R-sulfoxide reductase B3 chr12 Not Cancer Driver No 1 hippie, biogrid 49 42 14 14 1
MTFP1 MTFP1 Q9UDX5 Mitochondrial fission process protein 1 chr22 Not Cancer Driver No 1 hippie, biogrid 18 18 2 2 0
MTPN MTPN P58546 Myotrophin chr7 Not Cancer Driver No 1 hippie, biogrid 11 11 3 3 0
ODF3L2 ODF3L2 Q3SX64 Outer dense fiber protein 3-like protein 2 chr19 Not Cancer Driver No 1 hippie, biogrid 36 267 36 36 0
OMA1 OMA1 Q96E52 Metalloendopeptidase OMA1, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 52 34 4 4 0
OPTN_ENST00000263036 OPTN Q96CV9 Optineurin chr10 Not Cancer Driver No 1 hippie 58 470 51 51 6
PAK5 PAK5 Q9P286 Serine/threonine-protein kinase PAK 5 chr20 Not Cancer Driver No 1 intact, hippie 226 407 123 123 0
PARL PARL Q9H300 Presenilins-associated rhomboid-like protein, mitochondrial chr3 Not Cancer Driver No 1 intact, hippie 49 28 5 5 0
PDCD2L PDCD2L Q9BRP1 Programmed cell death protein 2-like chr19 Not Cancer Driver No 1 hippie, biogrid 35 83 6 6 0
PDK4 PDK4 Q16654 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial chr7 Not Cancer Driver No 1 intact, hippie, biogrid 70 14 2 2 0
PGM1_ENST00000371084 PGM1 P36871 Phosphoglucomutase-1 chr1 Not Cancer Driver No 1 hippie, biogrid 62 31 3 3 13
PHB2 PHB2 Q99623 Prohibitin-2 chr12 Not Cancer Driver No 1 hippie, biogrid 31 26 4 4 0
PHYHIPL PHYHIPL Q96FC7 Phytanoyl-CoA hydroxylase-interacting protein-like chr10 Not Cancer Driver No 1 hippie 49 68 9 9 0
PLGRKT PLGRKT Q9HBL7 Plasminogen receptor (KT) chr9 Not Cancer Driver No 1 intact, hippie 17 0 0 0 0
PMP22_ENST00000612492 PMP22 Q01453 Peripheral myelin protein 22 chr17 Not Cancer Driver No 1 intact 20 0 0 0 37
PMPCA PMPCA Q10713 Mitochondrial-processing peptidase subunit alpha chr9 Not Cancer Driver No 1 hippie, biogrid 67 23 3 3 4
PPA1 PPA1 Q15181 Inorganic pyrophosphatase chr10 Not Cancer Driver No 1 hippie, biogrid 31 24 0 0 0
PRDX6 PRDX6 P30041 Peroxiredoxin-6 chr1 Not Cancer Driver No 1 hippie, biogrid 46 13 4 4 0
PRPF40A PRPF40A O75400 Pre-mRNA-processing factor 40 homolog A chr2 Not Cancer Driver No 1 intact, hippie 83 694 57 57 0
PSMD14 PSMD14 O00487 26S proteasome non-ATPase regulatory subunit 14 chr2 Not Cancer Driver No 1 hippie 23 67 6 6 0
RAN_ENST00000392369 RAN P62826 GTP-binding nuclear protein Ran chr12 Not Cancer Driver No 1 hippie 20 14 1 1 0
RASSF2 RASSF2 P50749 Ras association domain-containing protein 2 chr20 Not Cancer Driver No 1 intact, hippie, biogrid 90 126 44 44 0
SCAF4 SCAF4 O95104 SR-related and CTD-associated factor 4 chr21 Not Cancer Driver No 1 hippie, biogrid 162 938 132 132 0
SCO1 SCO1 O75880 Protein SCO1 homolog, mitochondrial chr17 Not Cancer Driver No 1 intact, hippie 35 79 7 7 1
SDHAF2 SDHAF2 Q9NX18 Succinate dehydrogenase assembly factor 2, mitochondrial chr11 Census Yes 1 hippie, biogrid 29 22 5 5 1
SELENBP1_ENST00000368868 SELENBP1 Q13228 Methanethiol oxidase chr1 Not Cancer Driver No 1 hippie, biogrid 67 32 5 5 2
SFXN1 SFXN1 Q9H9B4 Sideroflexin-1 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 31 29 1 1 0
SLC16A11 SLC16A11 Q8NCK7 Monocarboxylate transporter 11 chr17 Not Cancer Driver No 1 hippie 33 72 5 5 0
SLC25A12 SLC25A12 O75746 Calcium-binding mitochondrial carrier protein Aralar1 chr2 Not Cancer Driver No 1 hippie, biogrid 110 21 7 7 2
SLC25A51_ENST00000242275 SLC25A51 Q9H1U9 Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51 chr9 Not Cancer Driver No 1 hippie, biogrid 31 21 0 0 0
SNRPB SNRPB P14678 Small nuclear ribonucleoprotein-associated proteins B and B' chr20 Not Cancer Driver No 1 intact, hippie 39 182 34 34 4
SPRED1 SPRED1 Q7Z699 Sprouty-related, EVH1 domain-containing protein 1 chr15 Not Cancer Driver No 1 intact, hippie 71 194 35 35 2
SPRYD7 SPRYD7 Q5W111 SPRY domain-containing protein 7 chr13 Not Cancer Driver No 1 hippie, biogrid 20 29 6 6 0
SUOX_ENST00000356124 SUOX P51687 Sulfite oxidase, mitochondrial chr12 Not Cancer Driver No 1 intact, hippie 68 184 32 32 11
SURF1 SURF1 Q15526 Surfeit locus protein 1 chr9 Not Cancer Driver No 1 hippie, biogrid 17 82 6 6 11
SVIL SVIL O95425 Supervillin chr10 Not Cancer Driver No 1 hippie, biogrid 308 1423 192 192 0
TBCA_ENST00000380377 TBCA O75347 Tubulin-specific chaperone A chr5 Not Cancer Driver No 1 hippie, biogrid 8 30 1 1 0
TDGF1 TDGF1 P13385 Teratocarcinoma-derived growth factor 1 chr3 Not Cancer Driver No 1 hippie, biogrid 39 25 2 2 0
TENT5B TENT5B Q96A09 Terminal nucleotidyltransferase 5B chr1 Not Cancer Driver No 1 hippie 52 57 6 6 0
TIMM29 TIMM29 Q9BSF4 Mitochondrial import inner membrane translocase subunit Tim29 chr19 Not Cancer Driver No 1 hippie 9 4 0 0 0
TIMP3 TIMP3 P35625 Metalloproteinase inhibitor 3 chr22 Not Cancer Driver No 1 hippie, biogrid 43 3 1 1 5
TRIM55 TRIM55 Q9BYV6 Tripartite motif-containing protein 55 chr8 Not Cancer Driver No 1 intact, hippie, biogrid 134 276 78 78 0
TRIM63 TRIM63 Q969Q1 E3 ubiquitin-protein ligase TRIM63 chr1 Not Cancer Driver No 1 hippie, biogrid 47 71 13 13 0
TXNDC17 TXNDC17 Q9BRA2 Thioredoxin domain-containing protein 17 chr17 Not Cancer Driver No 1 hippie, biogrid 8 0 0 0 0
VMA21 VMA21 Q3ZAQ7 Vacuolar ATPase assembly integral membrane protein VMA21 chrX Not Cancer Driver No 1 hippie, biogrid 18 7 1 1 0
WDHD1 WDHD1 O75717 WD repeat and HMG-box DNA-binding protein 1 chr14 Not Cancer Driver No 1 hippie, biogrid 100 474 31 31 0
YME1L1 YME1L1 Q96TA2 ATP-dependent zinc metalloprotease YME1L1 chr10 Not Cancer Driver No 1 intact, hippie 112 136 14 14 1
ZFAND5 ZFAND5 O76080 AN1-type zinc finger protein 5 chr9 Not Cancer Driver No 1 hippie 31 162 19 19 0