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CNN3 ,CNN3 ,Q15417
  • Number of Interaction partner in intact: 12
  • Number of Interaction partner in biogrid: 9
  • Number of Interaction partner in hippie: 75
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 1 hippie, biogrid 112 43 5 5 5
ACTC1 ACTC1 P68032 Actin, alpha cardiac muscle 1 chr15 Not Cancer Driver No 1 hippie 114 48 19 19 11
ATG5_ENST00000343245 ATG5 Q9H1Y0 Autophagy protein 5 chr6 Not Cancer Driver No 1 hippie 40 25 6 6 1
BICD1 BICD1 Q96G01 Protein bicaudal D homolog 1 chr12 Not Cancer Driver No 1 hippie 124 656 86 86 0
BICD2_ENST00000375512 BICD2 Q8TD16 Protein bicaudal D homolog 2 chr9 Not Cancer Driver No 1 hippie 115 546 73 73 10
C6orf89_ENST00000480824 C6orf89 Q6UWU4 Bombesin receptor-activated protein C6orf89 chr6 Not Cancer Driver No 1 hippie 38 29 2 2 0
CARM1 CARM1 Q86X55 Histone-arginine methyltransferase CARM1 chr19 Not Cancer Driver No 2 intact, hippie, biogrid 62 102 10 10 0
CDC73 CDC73 Q6P1J9 Parafibromin chr1 Census, Compendium Yes 1 hippie 110 210 39 39 2
CDH1 CDH1 P12830 Cadherin-1 chr16 Census, Compendium Yes 1 hippie 150 400 82 82 5
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 intact, hippie 287 145 18 18 151
CHD5 CHD5 Q8TDI0 Chromodomain-helicase-DNA-binding protein 5 chr1 Not Cancer Driver No 1 hippie 365 931 183 183 0
CLEC14A CLEC14A Q86T13 C-type lectin domain family 14 member A chr14 Not Cancer Driver No 1 hippie 147 182 60 60 0
CNN2_ENST00000263097 CNN2 Q99439 Calponin-2 chr19 Not Cancer Driver No 3 intact, hippie, biogrid 35 166 23 23 0
CRIM1 CRIM1 Q9NZV1 Cysteine-rich motor neuron 1 protein chr2 Not Cancer Driver No 1 hippie 133 35 4 4 0
CRMP1_ENST00000397890 CRMP1 Q14194 Dihydropyrimidinase-related protein 1 chr4 Not Cancer Driver No 1 hippie, biogrid 122 96 15 15 0
CTBP1 CTBP1 Q13363 C-terminal-binding protein 1 chr4 Not Cancer Driver No 1 intact, hippie 42 123 9 9 1
CYLD CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 Census, Compendium Yes 1 hippie 116 213 31 31 3
DDX10 DDX10 Q13206 Probable ATP-dependent RNA helicase DDX10 chr11 Census Yes 1 hippie 93 400 46 46 0
DHX30 DHX30 Q7L2E3 ATP-dependent RNA helicase DHX30 chr3 Not Cancer Driver No 1 hippie 165 260 40 40 6
DUSP13_ENST00000472493 DUSP13 Q9UII6 Dual specificity protein phosphatase 13 isoform B chr10 Not Cancer Driver No 1 hippie 45 16 1 1 0
EEF2 EEF2 P13639 Elongation factor 2 chr19 Not Cancer Driver No 1 hippie 111 78 14 14 1
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
EMD EMD P50402 Emerin chrX Not Cancer Driver No 1 hippie 42 160 28 28 4
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 334 1790 196 196 1
EP400 EP400 Q96L91 E1A-binding protein p400 chr12 Not Cancer Driver No 1 hippie 397 2064 234 234 0
F2RL1 F2RL1 P55085 Proteinase-activated receptor 2 chr5 Not Cancer Driver No 1 intact, hippie 55 7 2 2 0
FXR2 FXR2 P51116 Fragile X mental retardation syndrome-related protein 2 chr17 Not Cancer Driver No 1 hippie 68 388 42 42 0
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 Not Cancer Driver No 1 hippie 92 70 13 13 0
G3BP1 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 Not Cancer Driver No 1 hippie 85 352 65 65 0
GABARAP GABARAP O95166 Gamma-aminobutyric acid receptor-associated protein chr17 Not Cancer Driver No 1 hippie 9 11 0 0 0
GABARAPL1_ENST00000545887 GABARAPL1 Q9H0R8 Gamma-aminobutyric acid receptor-associated protein-like 1 chr12 Not Cancer Driver No 1 hippie 19 10 1 1 0
GALNT5 GALNT5 Q7Z7M9 Polypeptide N-acetylgalactosaminyltransferase 5 chr2 Not Cancer Driver No 1 hippie 147 399 56 56 0
GHITM GHITM Q9H3K2 Growth hormone-inducible transmembrane protein chr10 Not Cancer Driver No 1 hippie 50 8 0 0 0
GRN GRN P28799 Progranulin chr17 Not Cancer Driver No 1 hippie 76 29 6 6 1
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 Not Cancer Driver No 1 intact, hippie 47 135 10 10 0
HMGB2 HMGB2 P26583 High mobility group protein B2 chr4 Not Cancer Driver No 1 hippie 38 207 38 38 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 Not Cancer Driver No 1 hippie, biogrid 24 200 13 13 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 intact, hippie 149 251 52 52 0
ITGB8 ITGB8 P26012 Integrin beta-8 chr7 Not Cancer Driver No 1 hippie 126 26 3 3 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
LAMA4 LAMA4 Q16363 Laminin subunit alpha-4 chr6 Not Cancer Driver No 1 hippie 323 486 87 87 1
LCP1 LCP1 P13796 Plastin-2 chr13 Census Yes 1 hippie 99 73 11 11 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 519 90 17 17 23
MTHFD1L_ENST00000367321 MTHFD1L Q6UB35 Monofunctional C1-tetrahydrofolate synthase, mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 117 139 11 11 0
NAA40 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 22 30 3 3 0
NCL NCL P19338 Nucleolin chr2 Not Cancer Driver No 1 hippie 85 569 68 68 0
NEFM NEFM P07197 Neurofilament medium polypeptide chr8 Not Cancer Driver No 1 hippie 182 767 147 147 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
OTUB1_ENST00000428192 OTUB1 Q96FW1 Ubiquitin thioesterase OTUB1 chr11 Not Cancer Driver No 1 intact, hippie 31 33 2 2 0
PAN2_ENST00000548043 PAN2 Q504Q3 PAN2-PAN3 deadenylation complex catalytic subunit PAN2 chr12 Not Cancer Driver No 1 hippie 139 78 10 10 0
PHF12 PHF12 Q96QT6 PHD finger protein 12 chr17 Not Cancer Driver No 1 hippie 107 619 68 68 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PLEKHA7 PLEKHA7 Q6IQ23 Pleckstrin homology domain-containing family A member 7 chr11 Not Cancer Driver No 1 intact, hippie 152 919 121 121 0
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 Not Cancer Driver No 1 hippie 538 421 61 61 2
PTPN13_ENST00000411767 PTPN13 Q12923 Tyrosine-protein phosphatase non-receptor type 13 chr4 Census, Compendium Yes 1 hippie 299 1231 149 149 0
RDX_ENST00000343115 RDX P35241 Radixin chr11 Not Cancer Driver No 1 hippie 71 297 37 37 1
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 138 608 71 71 1
RPS23 RPS23 P62266 40S ribosomal protein S23 chr5 Not Cancer Driver No 1 hippie 8 35 1 1 2
RPS27 RPS27 P42677 40S ribosomal protein S27 chr1 Not Cancer Driver No 1 hippie 10 29 7 7 0
SCYL3_ENST00000367770 SCYL3 Q8IZE3 Protein-associating with the carboxyl-terminal domain of ezrin chr1 Not Cancer Driver No 1 intact, hippie, biogrid 81 249 28 28 0
SDCBP_ENST00000260130 SDCBP O00560 Syntenin-1 chr8 Not Cancer Driver No 1 hippie 39 17 2 2 0
SEPHS1 SEPHS1 P49903 Selenide, water dikinase 1 chr10 Not Cancer Driver No 1 hippie 58 29 10 10 0
SIPA1L1 SIPA1L1 O43166 Signal-induced proliferation-associated 1-like protein 1 chr14 Not Cancer Driver No 1 hippie 321 1175 226 226 0
SLX4 SLX4 Q8IY92 Structure-specific endonuclease subunit SLX4 chr16 Not Cancer Driver No 1 intact, hippie 271 1573 232 232 0
SPAG17 SPAG17 Q6Q759 Sperm-associated antigen 17 chr1 Not Cancer Driver No 1 hippie 431 1169 227 227 0
TAGLN2_ENST00000368097 TAGLN2 P37802 Transgelin-2 chr1 Not Cancer Driver No 1 hippie 28 83 12 12 0
TDRKH_ENST00000368827 TDRKH Q9Y2W6 Tudor and KH domain-containing protein chr1 Not Cancer Driver No 1 hippie 76 185 27 27 0
TEC TEC P42680 Tyrosine-protein kinase Tec chr4 Census, Compendium Yes 1 hippie, biogrid 91 57 15 15 0
TES TES Q9UGI8 Testin chr7 Not Cancer Driver No 1 hippie 56 100 7 7 0
THRAP3_ENST00000469141 THRAP3 Q9Y2W1 Thyroid hormone receptor-associated protein 3 chr1 Census Yes 1 hippie 137 955 137 137 0
TNIP2 TNIP2 Q8NFZ5 TNFAIP3-interacting protein 2 chr4 Not Cancer Driver No 1 hippie 43 316 36 36 0
TSC2 TSC2 P49815 Tuberin chr16 Census, Compendium Yes 1 hippie 192 563 50 50 53
UIMC1_ENST00000511320 UIMC1 Q96RL1 BRCA1-A complex subunit RAP80 chr5 Not Cancer Driver No 1 hippie 64 609 51 51 0
VKORC1 VKORC1 Q9BQB6 Vitamin K epoxide reductase complex subunit 1 chr16 Not Cancer Driver No 1 hippie 14 3 0 0 19
YKT6 YKT6 O15498 Synaptobrevin homolog YKT6 chr7 Not Cancer Driver No 1 hippie, biogrid 19 21 2 2 0