Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ABI1 | ABI1 | Q8IZP0 | Abl interactor 1 | chr10 | Census, Compendium | Yes | 1 | hippie | 55 | 360 | 39 | 39 | 0 |
ACE2 | ACE2 | Q9BYF1 | Angiotensin-converting enzyme 2 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 104 | 68 | 5 | 5 | 0 |
ACO2 | ACO2 | Q99798 | Aconitate hydratase, mitochondrial | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 94 | 172 | 19 | 19 | 5 |
ACOT13 | ACOT13 | Q9NPJ3 | Acyl-coenzyme A thioesterase 13 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 23 | 2 | 2 | 0 |
AGR2 | AGR2 | O95994 | Anterior gradient protein 2 homolog | chr7 | Not Cancer Driver | No | 1 | hippie | 23 | 20 | 2 | 2 | 0 |
ATG5_ENST00000343245 | ATG5 | Q9H1Y0 | Autophagy protein 5 | chr6 | Not Cancer Driver | No | 1 | hippie | 40 | 25 | 6 | 6 | 1 |
BACE1 | BACE1 | P56817 | Beta-secretase 1 | chr11 | Not Cancer Driver | No | 1 | hippie | 55 | 53 | 5 | 5 | 0 |
BRD4 | BRD4 | O60885 | Bromodomain-containing protein 4 | chr19 | Census, Compendium | Yes | 1 | hippie | 193 | 1182 | 172 | 172 | 0 |
BSG | BSG | P35613 | Basigin | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 123 | 17 | 17 | 0 |
CAPN1_ENST00000533129 | CAPN1 | P07384 | Calpain-1 catalytic subunit | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 68 | 32 | 2 | 2 | 1 |
CAV1 | CAV1 | Q03135 | Caveolin-1 | chr7 | Not Cancer Driver | No | 1 | hippie | 30 | 2 | 0 | 0 | 0 |
CDC42_ENST00000344548 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | Not Cancer Driver | No | 1 | hippie | 39 | 23 | 2 | 2 | 1 |
CDK15 | CDK15 | Q96Q40 | Cyclin-dependent kinase 15 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 66 | 35 | 4 | 4 | 0 |
CFTR | CFTR | P13569 | Cystic fibrosis transmembrane conductance regulator | chr7 | Not Cancer Driver | No | 1 | hippie | 287 | 145 | 18 | 18 | 151 |
CIDEB | CIDEB | Q9UHD4 | Cell death activator CIDE-B | chr14 | Not Cancer Driver | No | 1 | intact, hippie | 19 | 23 | 1 | 1 | 0 |
CIT_ENST00000261833 | CIT | O14578 | Citron Rho-interacting kinase | chr12 | Not Cancer Driver | No | 1 | hippie | 284 | 1017 | 160 | 160 | 3 |
CLIC1_ENST00000375779 | CLIC1 | O00299 | Chloride intracellular channel protein 1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 32 | 27 | 5 | 5 | 0 |
CLIC4 | CLIC4 | Q9Y696 | Chloride intracellular channel protein 4 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 49 | 4 | 4 | 0 |
DDAH1 | DDAH1 | O94760 | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 44 | 3 | 3 | 0 |
ECE2 | ECE2 | P0DPD6 | Endothelin-converting enzyme 2 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 178 | 149 | 40 | 40 | 0 |
ECHS1 | ECHS1 | P30084 | Enoyl-CoA hydratase, mitochondrial | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 7 | 1 | 1 | 14 |
EIF1B | EIF1B | O60739 | Eukaryotic translation initiation factor 1b | chr3 | Not Cancer Driver | No | 1 | hippie | 12 | 6 | 0 | 0 | 0 |
EIF6_ENST00000374436 | EIF6 | P56537 | Eukaryotic translation initiation factor 6 | chr20 | Not Cancer Driver | No | 1 | hippie | 30 | 17 | 3 | 3 | 0 |
ELAVL1 | ELAVL1 | Q15717 | ELAV-like protein 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 69 | 43 | 5 | 5 | 0 |
EP300 | EP300 | Q09472 | Histone acetyltransferase p300 | chr22 | Census, Compendium | Yes | 1 | hippie | 334 | 1790 | 196 | 196 | 1 |
ETFA | ETFA | P13804 | Electron transfer flavoprotein subunit alpha, mitochondrial | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 30 | 34 | 2 | 2 | 3 |
FAHD2A | FAHD2A | Q96GK7 | Fumarylacetoacetate hydrolase domain-containing protein 2A | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 39 | 8 | 2 | 2 | 0 |
FDX1 | FDX1 | P10109 | Adrenodoxin, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 12 | 61 | 2 | 2 | 0 |
FEN1 | FEN1 | P39748 | Flap endonuclease 1 | chr11 | Census | Yes | 1 | hippie, biogrid | 35 | 111 | 11 | 11 | 0 |
FH | FH | P07954 | Fumarate hydratase, mitochondrial | chr1 | Census, Compendium | Yes | 1 | hippie, biogrid | 67 | 76 | 5 | 5 | 13 |
FURIN_ENST00000610579 | FURIN | P09958 | Furin | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 93 | 283 | 35 | 35 | 0 |
GCSH | GCSH | P23434 | Glycine cleavage system H protein, mitochondrial | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 25 | 0 | 0 | 0 |
GLOD4_ENST00000301328 | GLOD4 | Q9HC38 | Glyoxalase domain-containing protein 4 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 44 | 3 | 3 | 0 |
GLRX5 | GLRX5 | Q86SX6 | Glutaredoxin-related protein 5, mitochondrial | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 7 | 23 | 0 | 0 | 2 |
GOT1 | GOT1 | P17174 | Aspartate aminotransferase, cytoplasmic | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 56 | 35 | 5 | 5 | 0 |
GPC1 | GPC1 | P35052 | Glypican-1 | chr2 | Not Cancer Driver | No | 1 | hippie | 58 | 166 | 14 | 14 | 0 |
GPI_ENST00000644934 | GPI | P06744 | Glucose-6-phosphate isomerase | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 77 | 73 | 11 | 11 | 24 |
GRHPR | GRHPR | Q9UBQ7 | Glyoxylate reductase/hydroxypyruvate reductase | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 36 | 4 | 4 | 0 |
GRPEL1 | GRPEL1 | Q9HAV7 | GrpE protein homolog 1, mitochondrial | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 22 | 88 | 7 | 7 | 0 |
GSTP1_ENST00000642444 | GSTP1 | P09211 | Glutathione S-transferase P | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 32 | 0 | 0 | 0 | 0 |
HDHD3 | HDHD3 | Q9BSH5 | Haloacid dehalogenase-like hydrolase domain-containing protein 3 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 0 | 0 | 0 | 0 |
HINT2 | HINT2 | Q9BX68 | Adenosine 5'-monophosphoramidase HINT2 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 10 | 29 | 2 | 2 | 0 |
HSCB | HSCB | Q8IWL3 | Iron-sulfur cluster co-chaperone protein HscB | chr22 | Not Cancer Driver | No | 1 | hippie | 36 | 25 | 6 | 6 | 0 |
KSR1_ENST00000644974 | KSR1 | Q8IVT5 | Kinase suppressor of Ras 1 | chr17 | Not Cancer Driver | No | 1 | hippie | 114 | 404 | 58 | 58 | 0 |
LACTB2 | LACTB2 | Q53H82 | Endoribonuclease LACTB2 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 21 | 1 | 1 | 0 |
LRRK2 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | Not Cancer Driver | No | 1 | hippie | 519 | 90 | 17 | 17 | 23 |
MAP1LC3B | MAP1LC3B | Q9GZQ8 | Microtubule-associated proteins 1A/1B light chain 3B | chr16 | Not Cancer Driver | No | 1 | hippie | 10 | 17 | 1 | 1 | 0 |
MCC_ENST00000302475 | MCC | P23508 | Colorectal mutant cancer protein | chr5 | Not Cancer Driver | No | 1 | hippie | 136 | 589 | 92 | 92 | 0 |
MOK | MOK | Q9UQ07 | MAPK/MAK/MRK overlapping kinase | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 44 | 135 | 13 | 13 | 0 |
MOV10_ENST00000357443 | MOV10 | Q9HCE1 | Helicase MOV-10 | chr1 | Not Cancer Driver | No | 1 | hippie | 110 | 101 | 8 | 8 | 0 |
MPST_ENST00000341116 | MPST | P25325 | 3-mercaptopyruvate sulfurtransferase | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 72 | 8 | 8 | 0 |
NDUFAB1_ENST00000007516 | NDUFAB1 | O14561 | Acyl carrier protein, mitochondrial | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 0 | 0 | 0 | 0 |
NIT2 | NIT2 | Q9NQR4 | Omega-amidase NIT2 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 47 | 0 | 0 | 0 | 0 |
NR2C2_ENST00000393102 | NR2C2 | P49116 | Nuclear receptor subfamily 2 group C member 2 | chr3 | Not Cancer Driver | No | 1 | hippie | 62 | 186 | 24 | 24 | 0 |
NRP1 | NRP1 | O14786 | Neuropilin-1 | chr10 | Compendium | Yes | 1 | hippie, biogrid | 146 | 211 | 31 | 31 | 0 |
NXF1_ENST00000294172 | NXF1 | Q9UBU9 | Nuclear RNA export factor 1 | chr11 | Compendium | Yes | 1 | hippie | 100 | 163 | 32 | 32 | 0 |
OXCT1 | OXCT1 | P55809 | Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 80 | 39 | 5 | 5 | 11 |
PARK7_ENST00000377488 | PARK7 | Q99497 | Parkinson disease protein 7 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 11 | 30 | 0 | 0 | 5 |
PDHA1_ENST00000422285 | PDHA1 | P08559 | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 70 | 43 | 6 | 6 | 20 |
PDP1_ENST00000297598 | PDP1 | Q9P0J1 | [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 64 | 96 | 9 | 9 | 0 |
PGM1_ENST00000371084 | PGM1 | P36871 | Phosphoglucomutase-1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 62 | 31 | 3 | 3 | 13 |
PLEKHA4 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 136 | 687 | 128 | 128 | 0 |
POLDIP2 | POLDIP2 | Q9Y2S7 | Polymerase delta-interacting protein 2 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 36 | 94 | 13 | 13 | 0 |
PRKAB1 | PRKAB1 | Q9Y478 | 5'-AMP-activated protein kinase subunit beta-1 | chr12 | Not Cancer Driver | No | 1 | hippie | 39 | 124 | 13 | 13 | 0 |
PRKD1_ENST00000616995 | PRKD1 | Q15139 | Serine/threonine-protein kinase D1 | chr14 | Census | Yes | 1 | hippie | 201 | 189 | 33 | 33 | 2 |
RAC1_ENST00000348035 | RAC1 | P63000 | Ras-related C3 botulinum toxin substrate 1 | chr7 | Census, Compendium | Yes | 1 | hippie | 66 | 2 | 1 | 1 | 6 |
RHOA | RHOA | P61586 | Transforming protein RhoA | chr3 | Census, Compendium | Yes | 1 | hippie | 99 | 46 | 13 | 13 | 2 |
RHOB | RHOB | P62745 | Rho-related GTP-binding protein RhoB | chr2 | Not Cancer Driver | No | 1 | hippie | 52 | 19 | 2 | 2 | 0 |
RHOD | RHOD | O00212 | Rho-related GTP-binding protein RhoD | chr11 | Not Cancer Driver | No | 1 | hippie | 20 | 10 | 0 | 0 | 0 |
RHOF | RHOF | Q9HBH0 | Rho-related GTP-binding protein RhoF | chr12 | Not Cancer Driver | No | 1 | hippie | 18 | 10 | 0 | 0 | 0 |
RHOH_ENST00000617441 | RHOH | Q15669 | Rho-related GTP-binding protein RhoH | chr4 | Census | Yes | 1 | hippie | 41 | 12 | 3 | 3 | 0 |
RHOJ | RHOJ | Q9H4E5 | Rho-related GTP-binding protein RhoJ | chr14 | Not Cancer Driver | No | 1 | hippie | 39 | 0 | 0 | 0 | 0 |
RHOU | RHOU | Q7L0Q8 | Rho-related GTP-binding protein RhoU | chr1 | Not Cancer Driver | No | 1 | hippie | 34 | 63 | 6 | 6 | 0 |
RND2 | RND2 | P52198 | Rho-related GTP-binding protein RhoN | chr17 | Not Cancer Driver | No | 1 | hippie | 19 | 54 | 4 | 4 | 0 |
RWDD2B | RWDD2B | P57060 | RWD domain-containing protein 2B | chr21 | Not Cancer Driver | No | 1 | hippie, biogrid | 38 | 41 | 0 | 0 | 0 |
SGTB | SGTB | Q96EQ0 | Small glutamine-rich tetratricopeptide repeat-containing protein beta | chr5 | Not Cancer Driver | No | 1 | hippie | 28 | 114 | 10 | 10 | 0 |
SH3GL3_ENST00000427482 | SH3GL3 | Q99963 | Endophilin-A3 | chr15 | Not Cancer Driver | No | 1 | hippie | 88 | 83 | 23 | 23 | 0 |
SPR | SPR | P35270 | Sepiapterin reductase | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 19 | 4 | 4 | 2 |
STX17_ENST00000534052 | STX17 | P56962 | Syntaxin-17 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 81 | 4 | 4 | 0 |
STXBP1_ENST00000373299 | STXBP1 | P61764 | Syntaxin-binding protein 1 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 97 | 111 | 23 | 23 | 18 |
SUCLG1 | SUCLG1 | P53597 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 48 | 57 | 8 | 8 | 3 |
SUCLG2_ENST00000307227 | SUCLG2 | Q96I99 | Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 48 | 12 | 2 | 2 | 0 |
TATDN1 | TATDN1 | Q6P1N9 | Deoxyribonuclease TATDN1 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 0 | 0 | 0 | 0 |
THEM4 | THEM4 | Q5T1C6 | Acyl-coenzyme A thioesterase THEM4 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 19 | 14 | 0 | 0 | 0 |
TNIK | TNIK | Q9UKE5 | TRAF2 and NCK-interacting protein kinase | chr3 | Not Cancer Driver | No | 1 | hippie | 254 | 781 | 156 | 156 | 0 |
TRIM25 | TRIM25 | Q14258 | E3 ubiquitin/ISG15 ligase TRIM25 | chr17 | Not Cancer Driver | No | 1 | hippie | 59 | 225 | 20 | 20 | 0 |
TTC19 | TTC19 | Q6DKK2 | Tetratricopeptide repeat protein 19, mitochondrial | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 76 | 3 | 3 | 0 |
YWHAZ_ENST00000395956 | YWHAZ | P63104 | 14-3-3 protein zeta/delta | chr8 | Not Cancer Driver | No | 1 | hippie | 30 | 81 | 10 | 10 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|