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CLIC4 ,CLIC4 ,Q9Y696
  • Uniprot Accession= Q9Y696
  • Ensembl Transcript= ENST00000374379.8
  • Uniprot Name= CLIC4
  • Name= Chloride intracellular channel protein 4
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 10
  • Number of Interaction partner in biogrid: 86
  • Number of Interaction partner in hippie: 106
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACADS ACADS P16219 Short-chain specific acyl-CoA dehydrogenase, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 53 16 3 3 10
ACO2 ACO2 Q99798 Aconitate hydratase, mitochondrial chr22 Not Cancer Driver No 1 hippie, biogrid 94 172 19 19 5
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 1 hippie 112 43 5 5 5
ADA ADA P00813 Adenosine deaminase chr20 Not Cancer Driver No 1 hippie, biogrid 50 44 9 9 27
ALDH4A1 ALDH4A1 P30038 Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 63 46 9 9 1
ARCN1 ARCN1 P48444 Coatomer subunit delta chr11 Not Cancer Driver No 1 hippie, biogrid 46 194 24 24 0
BSG BSG P35613 Basigin chr19 Not Cancer Driver No 1 hippie, biogrid 43 123 17 17 0
C1orf198 C1orf198 Q9H425 Uncharacterized protein C1orf198 chr1 Not Cancer Driver No 1 hippie, biogrid 40 303 36 36 0
CDA CDA P32320 Cytidine deaminase chr1 Not Cancer Driver No 1 hippie, biogrid 21 8 0 0 0
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 Not Cancer Driver No 1 hippie 24 0 0 0 0
CLEC4D CLEC4D Q8WXI8 C-type lectin domain family 4 member D chr12 Not Cancer Driver No 1 hippie, biogrid 59 17 3 3 0
CLIC1_ENST00000375779 CLIC1 O00299 Chloride intracellular channel protein 1 chr6 Not Cancer Driver No 1 hippie, biogrid 32 27 5 5 0
CLIC2 CLIC2 O15247 Chloride intracellular channel protein 2 chrX Not Cancer Driver No 3 intact, hippie, biogrid 46 58 6 6 1
CLIC5 CLIC5 Q9NZA1 Chloride intracellular channel protein 5 chr6 Not Cancer Driver No 3 intact, hippie, biogrid 50 205 22 22 0
CLIC6 CLIC6 Q96NY7 Chloride intracellular channel protein 6 chr21 Not Cancer Driver No 3 intact, hippie, biogrid 60 500 21 21 0
CLPP CLPP Q16740 ATP-dependent Clp protease proteolytic subunit, mitochondrial chr19 Not Cancer Driver No 1 hippie 22 83 9 9 3
CMPK1 CMPK1 P30085-3 Isoform 3 of UMP-CMP kinase chr1 Not Cancer Driver No 1 hippie, biogrid 23 30 3 3 0
COA7 COA7 Q96BR5 Cytochrome c oxidase assembly factor 7 chr1 Not Cancer Driver No 1 hippie, biogrid 25 39 7 7 2
COASY_ENST00000421097 COASY Q13057 Bifunctional coenzyme A synthase chr17 Not Cancer Driver No 1 hippie, biogrid 57 50 4 4 1
COX4I1 COX4I1 P13073 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 17 5 1 1 1
COX5A COX5A P20674 Cytochrome c oxidase subunit 5A, mitochondrial chr15 Not Cancer Driver No 1 hippie, biogrid 20 14 5 5 1
CRKL CRKL P46109 Crk-like protein chr22 Not Cancer Driver No 1 hippie, biogrid 38 160 25 25 0
CRYZ_ENST00000340866 CRYZ Q08257 Quinone oxidoreductase chr1 Not Cancer Driver No 1 hippie, biogrid 49 0 0 0 0
CSK_ENST00000439220 CSK P41240 Tyrosine-protein kinase CSK chr15 Not Cancer Driver No 1 hippie, biogrid 41 18 1 1 0
CTSB CTSB P07858 Cathepsin B chr8 Not Cancer Driver No 1 hippie, biogrid 41 7 2 2 0
CTSL CTSL P07711 Procathepsin L chr9 Not Cancer Driver No 1 hippie, biogrid 47 34 4 4 0
DAG1_ENST00000515359 DAG1 Q14118 Dystroglycan 1 chr3 Not Cancer Driver No 1 hippie, biogrid 102 485 61 61 4
DDAH1 DDAH1 O94760 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 chr1 Not Cancer Driver No 1 hippie, biogrid 28 44 3 3 0
DDAH2_ENST00000375787 DDAH2 O95865 N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 chr6 Not Cancer Driver No 1 hippie, biogrid 24 96 6 6 0
DDB1 DDB1 Q16531 DNA damage-binding protein 1 chr11 Not Cancer Driver No 1 biogrid 126 50 8 8 4
DNAJC9 DNAJC9 Q8WXX5 DnaJ homolog subfamily C member 9 chr10 Not Cancer Driver No 1 hippie, biogrid 28 126 15 15 0
DNM1 DNM1 Q05193 Dynamin-1 chr9 Not Cancer Driver No 1 hippie 98 280 23 23 4
ENO1 ENO1 P06733 Alpha-enolase chr1 Not Cancer Driver No 1 hippie, biogrid 51 21 2 2 0
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 Not Cancer Driver No 1 hippie 211 829 117 117 9
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
ETHE1 ETHE1 O95571 Persulfide dioxygenase ETHE1, mitochondrial chr19 Not Cancer Driver No 1 hippie, biogrid 21 6 0 0 9
EZR EZR P15311 Ezrin chr6 Census Yes 1 hippie, biogrid 66 295 35 35 0
FDPS_ENST00000368356 FDPS P14324 Farnesyl pyrophosphate synthase chr1 Not Cancer Driver No 1 hippie, biogrid 66 0 0 0 1
FXN FXN Q16595 Frataxin, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 16 73 0 0 8
G3BP1 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 Not Cancer Driver No 1 hippie 85 352 65 65 0
GCSH GCSH P23434 Glycine cleavage system H protein, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 15 25 0 0 0
GLRX5 GLRX5 Q86SX6 Glutaredoxin-related protein 5, mitochondrial chr14 Not Cancer Driver No 1 hippie, biogrid 7 23 0 0 2
GRHPR GRHPR Q9UBQ7 Glyoxylate reductase/hydroxypyruvate reductase chr9 Not Cancer Driver No 1 hippie, biogrid 31 36 4 4 0
GSTP1_ENST00000642444 GSTP1 P09211 Glutathione S-transferase P chr11 Not Cancer Driver No 1 hippie, biogrid 32 0 0 0 0
GUK1_ENST00000366718 GUK1 Q16774 Guanylate kinase chr1 Not Cancer Driver No 1 hippie, biogrid 28 71 9 9 0
HADH_ENST00000309522 HADH Q16836 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial chr4 Not Cancer Driver No 1 hippie, biogrid 33 22 5 5 3
HDHD3 HDHD3 Q9BSH5 Haloacid dehalogenase-like hydrolase domain-containing protein 3 chr9 Not Cancer Driver No 1 hippie, biogrid 28 0 0 0 0
HIBCH HIBCH Q6NVY1 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 42 26 0 0 1
HINT1 HINT1 P49773 Adenosine 5'-monophosphoramidase HINT1 chr5 Not Cancer Driver No 1 hippie, biogrid 11 6 0 0 6
HINT2 HINT2 Q9BX68 Adenosine 5'-monophosphoramidase HINT2 chr9 Not Cancer Driver No 1 hippie, biogrid 10 29 2 2 0
HNRNPA1 HNRNPA1 P09651 Heterogeneous nuclear ribonucleoprotein A1 chr12 Not Cancer Driver No 1 hippie, biogrid 70 290 58 58 4
HNRNPH2 HNRNPH2 P55795 Heterogeneous nuclear ribonucleoprotein H2 chrX Not Cancer Driver No 1 hippie, biogrid 73 168 34 34 3
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 1 intact, hippie 100 254 43 43 0
ICAM1 ICAM1 P05362 Intercellular adhesion molecule 1 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 61 251 28 28 0
IDH2 IDH2 P48735 Isocitrate dehydrogenase [NADP], mitochondrial chr15 Census, Compendium Yes 1 hippie, biogrid 74 59 1 1 7
LACTB2 LACTB2 Q53H82 Endoribonuclease LACTB2 chr8 Not Cancer Driver No 1 hippie, biogrid 34 21 1 1 0
LAP3 LAP3 P28838 Cytosol aminopeptidase chr4 Not Cancer Driver No 1 hippie, biogrid 59 99 14 14 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact 519 90 17 17 23
LSM3 LSM3 P62310 U6 snRNA-associated Sm-like protein LSm3 chr3 Not Cancer Driver No 1 hippie, biogrid 12 28 2 2 0
MAIP1 MAIP1 Q8WWC4 m-AAA protease-interacting protein 1, mitochondrial chr2 Not Cancer Driver No 1 hippie 28 12 0 0 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 Not Cancer Driver No 1 intact, hippie 128 750 126 126 18
MCC_ENST00000302475 MCC P23508 Colorectal mutant cancer protein chr5 Not Cancer Driver No 1 intact, hippie 136 589 92 92 0
MPST_ENST00000341116 MPST P25325 3-mercaptopyruvate sulfurtransferase chr22 Not Cancer Driver No 1 hippie, biogrid 20 72 8 8 0
MTPN MTPN P58546 Myotrophin chr7 Not Cancer Driver No 1 hippie, biogrid 11 11 3 3 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
NDRG1 NDRG1 Q92597 Protein NDRG1 chr8 Census Yes 1 hippie, biogrid 66 140 22 22 0
NDUFAB1_ENST00000007516 NDUFAB1 O14561 Acyl carrier protein, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 23 0 0 0 0
NENF NENF Q9UMX5 Neudesin chr1 Not Cancer Driver No 1 hippie, biogrid 15 98 7 7 0
NOS2 NOS2 P35228 Nitric oxide synthase, inducible chr17 Not Cancer Driver No 1 hippie, biogrid 207 201 33 33 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
P4HB P4HB P07237 Protein disulfide-isomerase chr17 Not Cancer Driver No 1 hippie, biogrid 61 79 15 15 1
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 Not Cancer Driver No 1 hippie, biogrid 11 30 0 0 5
PDCD6 PDCD6 O75340 Programmed cell death protein 6 chr5 Not Cancer Driver No 1 hippie, biogrid 21 24 1 1 0
PDP1_ENST00000297598 PDP1 Q9P0J1 [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial chr8 Not Cancer Driver No 1 hippie, biogrid 64 96 9 9 0
PGLS PGLS O95336 6-phosphogluconolactonase chr19 Not Cancer Driver No 1 hippie, biogrid 20 36 4 4 0
PMPCA PMPCA Q10713 Mitochondrial-processing peptidase subunit alpha chr9 Not Cancer Driver No 1 hippie, biogrid 67 23 3 3 4
PRDX2 PRDX2 P32119 Peroxiredoxin-2 chr19 Not Cancer Driver No 1 hippie, biogrid 24 30 4 4 0
PRDX6 PRDX6 P30041 Peroxiredoxin-6 chr1 Not Cancer Driver No 1 hippie, biogrid 46 13 4 4 0
PRNP PRNP P04156 Major prion protein chr20 Not Cancer Driver No 1 hippie 36 115 7 7 18
PSMA1_ENST00000396394 PSMA1 P25786 Proteasome subunit alpha type-1 chr11 Not Cancer Driver No 1 hippie, biogrid 48 51 9 9 0
PSMA2 PSMA2 P25787 Proteasome subunit alpha type-2 chr7 Not Cancer Driver No 1 hippie, biogrid 20 0 0 0 0
PSMA3 PSMA3 P25788 Proteasome subunit alpha type-3 chr14 Not Cancer Driver No 1 hippie, biogrid 27 30 5 5 0
PSMA5 PSMA5 P28066 Proteasome subunit alpha type-5 chr1 Not Cancer Driver No 1 hippie, biogrid 24 23 1 1 0
PSMB1 PSMB1 P20618 Proteasome subunit beta type-1 chr6 Not Cancer Driver No 1 hippie, biogrid 25 14 2 2 0
PSMB4 PSMB4 P28070 Proteasome subunit beta type-4 chr1 Not Cancer Driver No 1 hippie, biogrid 23 18 2 2 0
PSMB7 PSMB7 Q99436 Proteasome subunit beta type-7 chr9 Not Cancer Driver No 1 hippie, biogrid 25 26 3 3 0
RABIF RABIF P47224 Guanine nucleotide exchange factor MSS4 chr1 Not Cancer Driver No 1 hippie, biogrid 10 25 3 3 0
REL REL Q04864 Proto-oncogene c-Rel chr2 Census Yes 1 intact, hippie 68 363 43 43 0
SEPHS1 SEPHS1 P49903 Selenide, water dikinase 1 chr10 Not Cancer Driver No 1 hippie, biogrid 58 29 10 10 0
SHC1_ENST00000368445 SHC1 P29353 SHC-transforming protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 84 397 58 58 0
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 Not Cancer Driver No 1 hippie, biogrid 16 93 9 9 79
SPR SPR P35270 Sepiapterin reductase chr2 Not Cancer Driver No 1 hippie, biogrid 23 19 4 4 2
SPRTN SPRTN Q9H040 DNA-dependent metalloprotease SPRTN chr1 Not Cancer Driver No 1 hippie 73 252 38 38 1
ST13 ST13 P50502 Hsc70-interacting protein chr22 Not Cancer Driver No 1 hippie, biogrid 38 297 29 29 0
SUGT1 SUGT1 Q9Y2Z0 Protein SGT1 homolog chr13 Not Cancer Driver No 1 hippie, biogrid 31 119 5 5 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
TAGLN2_ENST00000368097 TAGLN2 P37802 Transgelin-2 chr1 Not Cancer Driver No 1 hippie, biogrid 28 83 12 12 0
TAGLN3 TAGLN3 Q9UI15 Transgelin-3 chr3 Not Cancer Driver No 1 hippie, biogrid 25 85 18 18 0
TBCA_ENST00000380377 TBCA O75347 Tubulin-specific chaperone A chr5 Not Cancer Driver No 1 hippie, biogrid 8 30 1 1 0
TPD52_ENST00000379097 TPD52 P55327 Tumor protein D52 chr8 Not Cancer Driver No 1 hippie, biogrid 25 177 19 19 0
TPI1_ENST00000396705 TPI1 P60174 Triosephosphate isomerase chr12 Not Cancer Driver No 1 hippie, biogrid 40 15 2 2 7
TPRN TPRN Q4KMQ1 Taperin chr9 Not Cancer Driver No 4 intact, hippie, biogrid 41 667 36 36 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
UBA2 UBA2 Q9UBT2 SUMO-activating enzyme subunit 2 chr19 Not Cancer Driver No 1 hippie, biogrid 84 219 33 33 0
UCHL1 UCHL1 P09936 Ubiquitin carboxyl-terminal hydrolase isozyme L1 chr4 Not Cancer Driver No 1 hippie, biogrid 33 34 7 7 4
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 Not Cancer Driver No 1 hippie 88 186 16 16 16
YWHAE YWHAE P62258 14-3-3 protein epsilon chr17 Census Yes 1 hippie 32 41 3 3 0
YWHAZ_ENST00000395956 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 1 hippie 30 81 10 10 0