Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACADS | ACADS | P16219 | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 53 | 16 | 3 | 3 | 10 |
| ACO2 | ACO2 | Q99798 | Aconitate hydratase, mitochondrial | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 94 | 172 | 19 | 19 | 5 |
| ACTB_ENST00000646664 | ACTB | P60709 | Actin, cytoplasmic 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 112 | 43 | 5 | 5 | 5 |
| ADA | ADA | P00813 | Adenosine deaminase | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 44 | 9 | 9 | 27 |
| ALDH4A1 | ALDH4A1 | P30038 | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 63 | 46 | 9 | 9 | 1 |
| ARCN1 | ARCN1 | P48444 | Coatomer subunit delta | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 46 | 194 | 24 | 24 | 0 |
| BSG | BSG | P35613 | Basigin | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 123 | 17 | 17 | 0 |
| C1orf198 | C1orf198 | Q9H425 | Uncharacterized protein C1orf198 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 40 | 303 | 36 | 36 | 0 |
| CDA | CDA | P32320 | Cytidine deaminase | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 21 | 8 | 0 | 0 | 0 |
| CDK2 | CDK2 | P24941 | Cyclin-dependent kinase 2 | chr12 | Not Cancer Driver | No | 1 | hippie | 24 | 0 | 0 | 0 | 0 |
| CLEC4D | CLEC4D | Q8WXI8 | C-type lectin domain family 4 member D | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 59 | 17 | 3 | 3 | 0 |
| CLIC1_ENST00000375779 | CLIC1 | O00299 | Chloride intracellular channel protein 1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 32 | 27 | 5 | 5 | 0 |
| CLIC2 | CLIC2 | O15247 | Chloride intracellular channel protein 2 | chrX | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 46 | 58 | 6 | 6 | 1 |
| CLIC5 | CLIC5 | Q9NZA1 | Chloride intracellular channel protein 5 | chr6 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 50 | 205 | 22 | 22 | 0 |
| CLIC6 | CLIC6 | Q96NY7 | Chloride intracellular channel protein 6 | chr21 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 60 | 500 | 21 | 21 | 0 |
| CLPP | CLPP | Q16740 | ATP-dependent Clp protease proteolytic subunit, mitochondrial | chr19 | Not Cancer Driver | No | 1 | hippie | 22 | 83 | 9 | 9 | 3 |
| CMPK1 | CMPK1 | P30085-3 | Isoform 3 of UMP-CMP kinase | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 30 | 3 | 3 | 0 |
| COA7 | COA7 | Q96BR5 | Cytochrome c oxidase assembly factor 7 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 39 | 7 | 7 | 2 |
| COASY_ENST00000421097 | COASY | Q13057 | Bifunctional coenzyme A synthase | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 57 | 50 | 4 | 4 | 1 |
| COX4I1 | COX4I1 | P13073 | Cytochrome c oxidase subunit 4 isoform 1, mitochondrial | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 17 | 5 | 1 | 1 | 1 |
| COX5A | COX5A | P20674 | Cytochrome c oxidase subunit 5A, mitochondrial | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 14 | 5 | 5 | 1 |
| CRKL | CRKL | P46109 | Crk-like protein | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 38 | 160 | 25 | 25 | 0 |
| CRYZ_ENST00000340866 | CRYZ | Q08257 | Quinone oxidoreductase | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 49 | 0 | 0 | 0 | 0 |
| CSK_ENST00000439220 | CSK | P41240 | Tyrosine-protein kinase CSK | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 18 | 1 | 1 | 0 |
| CTSB | CTSB | P07858 | Cathepsin B | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 7 | 2 | 2 | 0 |
| CTSL | CTSL | P07711 | Procathepsin L | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 47 | 34 | 4 | 4 | 0 |
| DAG1_ENST00000515359 | DAG1 | Q14118 | Dystroglycan 1 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 102 | 485 | 61 | 61 | 4 |
| DDAH1 | DDAH1 | O94760 | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 44 | 3 | 3 | 0 |
| DDAH2_ENST00000375787 | DDAH2 | O95865 | N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 96 | 6 | 6 | 0 |
| DDB1 | DDB1 | Q16531 | DNA damage-binding protein 1 | chr11 | Not Cancer Driver | No | 1 | biogrid | 126 | 50 | 8 | 8 | 4 |
| DNAJC9 | DNAJC9 | Q8WXX5 | DnaJ homolog subfamily C member 9 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 126 | 15 | 15 | 0 |
| DNM1 | DNM1 | Q05193 | Dynamin-1 | chr9 | Not Cancer Driver | No | 1 | hippie | 98 | 280 | 23 | 23 | 4 |
| ENO1 | ENO1 | P06733 | Alpha-enolase | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 21 | 2 | 2 | 0 |
| ERCC6 | ERCC6 | Q03468 | DNA excision repair protein ERCC-6 | chr10 | Not Cancer Driver | No | 1 | hippie | 211 | 829 | 117 | 117 | 9 |
| ESR2 | ESR2 | Q92731 | Estrogen receptor beta | chr14 | Not Cancer Driver | No | 1 | hippie | 90 | 92 | 11 | 11 | 1 |
| ETHE1 | ETHE1 | O95571 | Persulfide dioxygenase ETHE1, mitochondrial | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 21 | 6 | 0 | 0 | 9 |
| EZR | EZR | P15311 | Ezrin | chr6 | Census | Yes | 1 | hippie, biogrid | 66 | 295 | 35 | 35 | 0 |
| FDPS_ENST00000368356 | FDPS | P14324 | Farnesyl pyrophosphate synthase | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 66 | 0 | 0 | 0 | 1 |
| FXN | FXN | Q16595 | Frataxin, mitochondrial | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 73 | 0 | 0 | 8 |
| G3BP1 | G3BP1 | Q13283 | Ras GTPase-activating protein-binding protein 1 | chr5 | Not Cancer Driver | No | 1 | hippie | 85 | 352 | 65 | 65 | 0 |
| GCSH | GCSH | P23434 | Glycine cleavage system H protein, mitochondrial | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 25 | 0 | 0 | 0 |
| GLRX5 | GLRX5 | Q86SX6 | Glutaredoxin-related protein 5, mitochondrial | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 7 | 23 | 0 | 0 | 2 |
| GRHPR | GRHPR | Q9UBQ7 | Glyoxylate reductase/hydroxypyruvate reductase | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 36 | 4 | 4 | 0 |
| GSTP1_ENST00000642444 | GSTP1 | P09211 | Glutathione S-transferase P | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 32 | 0 | 0 | 0 | 0 |
| GUK1_ENST00000366718 | GUK1 | Q16774 | Guanylate kinase | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 71 | 9 | 9 | 0 |
| HADH_ENST00000309522 | HADH | Q16836 | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 33 | 22 | 5 | 5 | 3 |
| HDHD3 | HDHD3 | Q9BSH5 | Haloacid dehalogenase-like hydrolase domain-containing protein 3 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 0 | 0 | 0 | 0 |
| HIBCH | HIBCH | Q6NVY1 | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 42 | 26 | 0 | 0 | 1 |
| HINT1 | HINT1 | P49773 | Adenosine 5'-monophosphoramidase HINT1 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 11 | 6 | 0 | 0 | 6 |
| HINT2 | HINT2 | Q9BX68 | Adenosine 5'-monophosphoramidase HINT2 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 10 | 29 | 2 | 2 | 0 |
| HNRNPA1 | HNRNPA1 | P09651 | Heterogeneous nuclear ribonucleoprotein A1 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 70 | 290 | 58 | 58 | 4 |
| HNRNPH2 | HNRNPH2 | P55795 | Heterogeneous nuclear ribonucleoprotein H2 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 73 | 168 | 34 | 34 | 3 |
| HSP90AB1 | HSP90AB1 | P08238 | Heat shock protein HSP 90-beta | chr6 | Census, Compendium | Yes | 1 | intact, hippie | 100 | 254 | 43 | 43 | 0 |
| ICAM1 | ICAM1 | P05362 | Intercellular adhesion molecule 1 | chr19 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 61 | 251 | 28 | 28 | 0 |
| IDH2 | IDH2 | P48735 | Isocitrate dehydrogenase [NADP], mitochondrial | chr15 | Census, Compendium | Yes | 1 | hippie, biogrid | 74 | 59 | 1 | 1 | 7 |
| LACTB2 | LACTB2 | Q53H82 | Endoribonuclease LACTB2 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 21 | 1 | 1 | 0 |
| LAP3 | LAP3 | P28838 | Cytosol aminopeptidase | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 59 | 99 | 14 | 14 | 0 |
| LRRK2 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | Not Cancer Driver | No | 1 | intact | 519 | 90 | 17 | 17 | 23 |
| LSM3 | LSM3 | P62310 | U6 snRNA-associated Sm-like protein LSm3 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 12 | 28 | 2 | 2 | 0 |
| MAIP1 | MAIP1 | Q8WWC4 | m-AAA protease-interacting protein 1, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie | 28 | 12 | 0 | 0 | 0 |
| MAPT_ENST00000262410 | MAPT | P10636 | Microtubule-associated protein tau | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 128 | 750 | 126 | 126 | 18 |
| MCC_ENST00000302475 | MCC | P23508 | Colorectal mutant cancer protein | chr5 | Not Cancer Driver | No | 1 | intact, hippie | 136 | 589 | 92 | 92 | 0 |
| MPST_ENST00000341116 | MPST | P25325 | 3-mercaptopyruvate sulfurtransferase | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 72 | 8 | 8 | 0 |
| MTPN | MTPN | P58546 | Myotrophin | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 11 | 11 | 3 | 3 | 0 |
| MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | Census, Compendium | Yes | 1 | hippie | 80 | 299 | 46 | 46 | 0 |
| NDRG1 | NDRG1 | Q92597 | Protein NDRG1 | chr8 | Census | Yes | 1 | hippie, biogrid | 66 | 140 | 22 | 22 | 0 |
| NDUFAB1_ENST00000007516 | NDUFAB1 | O14561 | Acyl carrier protein, mitochondrial | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 0 | 0 | 0 | 0 |
| NENF | NENF | Q9UMX5 | Neudesin | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 98 | 7 | 7 | 0 |
| NOS2 | NOS2 | P35228 | Nitric oxide synthase, inducible | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 207 | 201 | 33 | 33 | 0 |
| NTRK1 | NTRK1 | P04629 | High affinity nerve growth factor receptor | chr1 | Census, Compendium | Yes | 1 | hippie | 168 | 57 | 8 | 8 | 25 |
| P4HB | P4HB | P07237 | Protein disulfide-isomerase | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 61 | 79 | 15 | 15 | 1 |
| PARK7_ENST00000377488 | PARK7 | Q99497 | Parkinson disease protein 7 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 11 | 30 | 0 | 0 | 5 |
| PDCD6 | PDCD6 | O75340 | Programmed cell death protein 6 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 21 | 24 | 1 | 1 | 0 |
| PDP1_ENST00000297598 | PDP1 | Q9P0J1 | [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 64 | 96 | 9 | 9 | 0 |
| PGLS | PGLS | O95336 | 6-phosphogluconolactonase | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 36 | 4 | 4 | 0 |
| PMPCA | PMPCA | Q10713 | Mitochondrial-processing peptidase subunit alpha | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 23 | 3 | 3 | 4 |
| PRDX2 | PRDX2 | P32119 | Peroxiredoxin-2 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 30 | 4 | 4 | 0 |
| PRDX6 | PRDX6 | P30041 | Peroxiredoxin-6 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 46 | 13 | 4 | 4 | 0 |
| PRNP | PRNP | P04156 | Major prion protein | chr20 | Not Cancer Driver | No | 1 | hippie | 36 | 115 | 7 | 7 | 18 |
| PSMA1_ENST00000396394 | PSMA1 | P25786 | Proteasome subunit alpha type-1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 48 | 51 | 9 | 9 | 0 |
| PSMA2 | PSMA2 | P25787 | Proteasome subunit alpha type-2 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 0 | 0 | 0 | 0 |
| PSMA3 | PSMA3 | P25788 | Proteasome subunit alpha type-3 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 30 | 5 | 5 | 0 |
| PSMA5 | PSMA5 | P28066 | Proteasome subunit alpha type-5 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 23 | 1 | 1 | 0 |
| PSMB1 | PSMB1 | P20618 | Proteasome subunit beta type-1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 14 | 2 | 2 | 0 |
| PSMB4 | PSMB4 | P28070 | Proteasome subunit beta type-4 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 18 | 2 | 2 | 0 |
| PSMB7 | PSMB7 | Q99436 | Proteasome subunit beta type-7 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 26 | 3 | 3 | 0 |
| RABIF | RABIF | P47224 | Guanine nucleotide exchange factor MSS4 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 10 | 25 | 3 | 3 | 0 |
| REL | REL | Q04864 | Proto-oncogene c-Rel | chr2 | Census | Yes | 1 | intact, hippie | 68 | 363 | 43 | 43 | 0 |
| SEPHS1 | SEPHS1 | P49903 | Selenide, water dikinase 1 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 29 | 10 | 10 | 0 |
| SHC1_ENST00000368445 | SHC1 | P29353 | SHC-transforming protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 84 | 397 | 58 | 58 | 0 |
| SOD1 | SOD1 | P00441 | Superoxide dismutase [Cu-Zn] | chr21 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 93 | 9 | 9 | 79 |
| SPR | SPR | P35270 | Sepiapterin reductase | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 19 | 4 | 4 | 2 |
| SPRTN | SPRTN | Q9H040 | DNA-dependent metalloprotease SPRTN | chr1 | Not Cancer Driver | No | 1 | hippie | 73 | 252 | 38 | 38 | 1 |
| ST13 | ST13 | P50502 | Hsc70-interacting protein | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 38 | 297 | 29 | 29 | 0 |
| SUGT1 | SUGT1 | Q9Y2Z0 | Protein SGT1 homolog | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 119 | 5 | 5 | 0 |
| SUMO2 | SUMO2 | P61956 | Small ubiquitin-related modifier 2 | chr17 | Not Cancer Driver | No | 1 | hippie | 9 | 69 | 6 | 6 | 0 |
| TAGLN2_ENST00000368097 | TAGLN2 | P37802 | Transgelin-2 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 83 | 12 | 12 | 0 |
| TAGLN3 | TAGLN3 | Q9UI15 | Transgelin-3 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 85 | 18 | 18 | 0 |
| TBCA_ENST00000380377 | TBCA | O75347 | Tubulin-specific chaperone A | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 8 | 30 | 1 | 1 | 0 |
| TPD52_ENST00000379097 | TPD52 | P55327 | Tumor protein D52 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 177 | 19 | 19 | 0 |
| TPI1_ENST00000396705 | TPI1 | P60174 | Triosephosphate isomerase | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 40 | 15 | 2 | 2 | 7 |
| TPRN | TPRN | Q4KMQ1 | Taperin | chr9 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 41 | 667 | 36 | 36 | 0 |
| TRIM25 | TRIM25 | Q14258 | E3 ubiquitin/ISG15 ligase TRIM25 | chr17 | Not Cancer Driver | No | 1 | hippie | 59 | 225 | 20 | 20 | 0 |
| UBA2 | UBA2 | Q9UBT2 | SUMO-activating enzyme subunit 2 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 84 | 219 | 33 | 33 | 0 |
| UCHL1 | UCHL1 | P09936 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 33 | 34 | 7 | 7 | 4 |
| VCP | VCP | P55072 | Transitional endoplasmic reticulum ATPase | chr9 | Not Cancer Driver | No | 1 | hippie | 88 | 186 | 16 | 16 | 16 |
| YWHAE | YWHAE | P62258 | 14-3-3 protein epsilon | chr17 | Census | Yes | 1 | hippie | 32 | 41 | 3 | 3 | 0 |
| YWHAZ_ENST00000395956 | YWHAZ | P63104 | 14-3-3 protein zeta/delta | chr8 | Not Cancer Driver | No | 1 | hippie | 30 | 81 | 10 | 10 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|