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CHRM3_ENST00000615928 ,CHRM3 ,P20309
  • Uniprot Accession= P20309
  • Ensembl Transcript= ENST00000615928.4
  • Uniprot Name= CHRM3
  • Name= Muscarinic acetylcholine receptor M3
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 48
  • Number of Interaction partner in biogrid: 51
  • Number of Interaction partner in hippie: 84
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ARF1_ENST00000272102 ARF1 P84077 ADP-ribosylation factor 1 chr1 Not Cancer Driver No 1 hippie 30 4 2 2 2
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 Not Cancer Driver No 1 hippie 18 5 0 0 0
ARL10 ARL10 Q8N8L6 ADP-ribosylation factor-like protein 10 chr5 Not Cancer Driver No 1 intact, hippie, biogrid 19 19 0 0 0
ATL2 ATL2 Q8NHH9 Atlastin-2 chr2 Not Cancer Driver No 2 intact, hippie, biogrid 64 75 5 5 0
ATP1A3_ENST00000302102 ATP1A3 P13637 Sodium/potassium-transporting ATPase subunit alpha-3 chr19 Not Cancer Driver No 1 hippie, biogrid 200 115 29 29 31
ATP1A4 ATP1A4 Q13733 Sodium/potassium-transporting ATPase subunit alpha-4 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 195 117 24 24 0
BSG BSG P35613 Basigin chr19 Not Cancer Driver No 1 hippie 43 123 17 17 0
C1orf112_ENST00000359326 C1orf112 Q9NSG2 Uncharacterized protein C1orf112 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 100 26 2 2 0
CALM1 CALM1 P0DP23 Calmodulin-1 chr14 Not Cancer Driver No 1 hippie 19 115 15 15 7
CAND2 CAND2 O75155 Cullin-associated NEDD8-dissociated protein 2 chr3 Not Cancer Driver No 1 intact, hippie, biogrid 133 96 16 16 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 Not Cancer Driver No 2 intact, hippie, biogrid 30 2 0 0 0
CCDC184 CCDC184 Q52MB2 Coiled-coil domain-containing protein 184 chr12 Not Cancer Driver No 1 intact, hippie 22 183 22 22 0
CD2BP2 CD2BP2 O95400 CD2 antigen cytoplasmic tail-binding protein 2 chr16 Not Cancer Driver No 1 intact, hippie 49 259 40 40 0
CERS6_ENST00000305747 CERS6 Q6ZMG9 Ceramide synthase 6 chr2 Not Cancer Driver No 1 hippie, biogrid 54 32 10 10 0
CHRM3_ENST00000615928 CHRM3 P20309 Muscarinic acetylcholine receptor M3 chr1 Not Cancer Driver No 1 intact, hippie 182 136 42 42 0
CHRM5 CHRM5 P08912 Muscarinic acetylcholine receptor M5 chr15 Not Cancer Driver No 1 intact, hippie 74 155 20 20 0
COMMD7 COMMD7 Q86VX2 COMM domain-containing protein 7 chr20 Not Cancer Driver No 1 intact, hippie 29 21 0 0 0
CSNK1A1_ENST00000377843 CSNK1A1 P48729 Casein kinase I isoform alpha chr5 Not Cancer Driver No 1 hippie 44 46 3 3 0
DCP2 DCP2 Q8IU60 m7GpppN-mRNA hydrolase chr5 Not Cancer Driver No 1 intact, hippie, biogrid 57 167 24 24 0
DNAJA3 DNAJA3 Q96EY1 DnaJ homolog subfamily A member 3, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie, biogrid 50 152 21 21 0
DYM DYM Q7RTS9 Dymeclin chr18 Not Cancer Driver No 2 intact, hippie, biogrid 78 21 0 0 3
EXOC2 EXOC2 Q96KP1 Exocyst complex component 2 chr6 Not Cancer Driver No 2 intact, hippie, biogrid 105 134 18 18 0
FAM241B FAM241B Q96D05 Protein FAM241B chr10 Not Cancer Driver No 1 intact, hippie 25 53 9 9 0
FARP2 FARP2 O94887 FERM, ARHGEF and pleckstrin domain-containing protein 2 chr2 Not Cancer Driver No 2 intact, hippie, biogrid 133 250 39 39 0
FASTKD1 FASTKD1 Q53R41 FAST kinase domain-containing protein 1, mitochondrial chr2 Not Cancer Driver No 2 intact, hippie, biogrid 125 0 0 0 0
FLT4 FLT4 P35916 Vascular endothelial growth factor receptor 3 chr5 Census, Compendium Yes 1 intact, hippie, biogrid 253 259 41 41 13
FTSJ1 FTSJ1 Q9UET6 Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase chrX Not Cancer Driver No 2 intact, hippie, biogrid 44 89 14 14 0
GBF1 GBF1 Q92538 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 chr10 Not Cancer Driver No 2 intact, hippie, biogrid 216 669 76 76 0
GNAQ GNAQ P50148 Guanine nucleotide-binding protein G(q) subunit alpha chr9 Census, Compendium Yes 1 hippie 57 14 1 1 1
GNAS_ENST00000371075 GNAS O95467 Neuroendocrine secretory protein 55 chr20 Census, Compendium Yes 1 hippie 71 221 65 65 0
GPN3_ENST00000228827 GPN3 Q9UHW5 GPN-loop GTPase 3 chr12 Not Cancer Driver No 2 intact, hippie, biogrid 28 19 0 0 0
GPRASP1_ENST00000415986 GPRASP1 Q5JY77 G-protein coupled receptor-associated sorting protein 1 chrX Not Cancer Driver No 1 hippie 217 918 133 133 0
GRK6_ENST00000355472 GRK6 P43250 G protein-coupled receptor kinase 6 chr5 Not Cancer Driver No 1 hippie 65 68 10 10 0
GTPBP2 GTPBP2 Q9BX10 GTP-binding protein 2 chr6 Not Cancer Driver No 2 intact, hippie, biogrid 53 89 5 5 0
GZMB GZMB P10144 Granzyme B chr14 Not Cancer Driver No 1 hippie 49 103 23 23 0
HEATR3 HEATR3 Q7Z4Q2 HEAT repeat-containing protein 3 chr16 Not Cancer Driver No 2 intact, hippie, biogrid 73 134 10 10 0
HNRNPL HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 89 283 29 29 0
HOOK2 HOOK2 Q96ED9 Protein Hook homolog 2 chr19 Not Cancer Driver No 2 intact, hippie, biogrid 94 487 62 62 0
IPO13 IPO13 O94829 Importin-13 chr1 Not Cancer Driver No 2 hippie, biogrid 98 42 7 7 0
IPO7 IPO7 O95373 Importin-7 chr11 Not Cancer Driver No 1 hippie, biogrid 138 202 30 30 0
IPO9 IPO9 Q96P70 Importin-9 chr1 Not Cancer Driver No 2 hippie, biogrid 145 102 22 22 0
ITPRIPL1_ENST00000439118 ITPRIPL1 Q6GPH6 Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1 chr2 Not Cancer Driver No 1 hippie, biogrid 65 39 3 3 0
JAKMIP1_ENST00000282924 JAKMIP1 Q96N16 Janus kinase and microtubule-interacting protein 1 chr4 Not Cancer Driver No 1 hippie 163 388 118 118 0
JPH1 JPH1 Q9HDC5 Junctophilin-1 chr8 Not Cancer Driver No 1 intact, hippie, biogrid 131 421 89 89 0
LRP10 LRP10 Q7Z4F1 Low-density lipoprotein receptor-related protein 10 chr14 Not Cancer Driver No 2 intact, hippie, biogrid 99 237 32 32 0
LTN1_ENST00000361371 LTN1 O94822 E3 ubiquitin-protein ligase listerin chr21 Not Cancer Driver No 2 intact, hippie, biogrid 192 124 23 23 0
MAGED2 MAGED2 Q9UNF1 Melanoma-associated antigen D2 chrX Not Cancer Driver No 1 hippie 99 326 53 53 1
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 Census, Compendium Yes 1 intact, hippie 56 297 37 37 0
NALCN NALCN Q8IZF0 Sodium leak channel NALCN chr13 Not Cancer Driver No 1 intact, hippie 499 260 74 74 11
NARS2 NARS2 Q96I59 Probable asparagine--tRNA ligase, mitochondrial chr11 Not Cancer Driver No 1 intact, hippie, biogrid 79 22 2 2 3
NEK4 NEK4 P51957 Serine/threonine-protein kinase Nek4 chr3 Not Cancer Driver No 1 hippie 78 492 49 49 0
NOCT NOCT Q9UK39 Nocturnin chr4 Not Cancer Driver No 1 intact, hippie 33 89 3 3 0
PBXIP1 PBXIP1 Q96AQ6 Pre-B-cell leukemia transcription factor-interacting protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 100 605 86 86 0
PEX1 PEX1 O43933 Peroxisome biogenesis factor 1 chr7 Not Cancer Driver No 1 hippie, biogrid 143 304 36 36 14
PI4KA PI4KA P42356 Phosphatidylinositol 4-kinase alpha chr22 Not Cancer Driver No 2 hippie, biogrid 267 142 11 11 1
PIGX_ENST00000392391 PIGX Q8TBF5 Phosphatidylinositol-glycan biosynthesis class X protein chr3 Not Cancer Driver No 2 intact, hippie, biogrid 27 0 0 0 0
PIK3CB_ENST00000477593 PIK3CB P42338 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform chr3 Census, Compendium Yes 2 intact, hippie, biogrid 150 42 4 4 0
PIK3R3_ENST00000372006 PIK3R3 Q92569 Phosphatidylinositol 3-kinase regulatory subunit gamma chr1 Not Cancer Driver No 1 hippie, biogrid 51 149 20 20 0
PLD2 PLD2 O14939 Phospholipase D2 chr17 Not Cancer Driver No 2 hippie, biogrid 107 97 8 8 0
POM121C_ENST00000607367 POM121C A8CG34 Nuclear envelope pore membrane protein POM 121C chr7 Not Cancer Driver No 1 intact, hippie 99 1117 91 91 0
PPP1R9B PPP1R9B Q96SB3 Neurabin-2 chr17 Not Cancer Driver No 1 hippie 47 695 35 35 0
PPP6R1_ENST00000587283 PPP6R1 Q9UPN7 Serine/threonine-protein phosphatase 6 regulatory subunit 1 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 82 471 47 47 0
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 Not Cancer Driver No 1 hippie, biogrid 538 421 61 61 2
PTRH2_ENST00000470557 PTRH2 Q9Y3E5 Peptidyl-tRNA hydrolase 2, mitochondrial chr17 Not Cancer Driver No 2 intact, hippie, biogrid 14 19 2 2 1
RAB5IF_ENST00000373852 RAB5IF Q9BUV8 Respirasome Complex Assembly Factor 1 chr20 Not Cancer Driver No 1 hippie 7 13 0 0 0
RANBP6 RANBP6 O60518 Ran-binding protein 6 chr9 Not Cancer Driver No 1 hippie, biogrid 152 46 4 4 0
RGS4_ENST00000367909 RGS4 P49798 Regulator of G-protein signaling 4 chr1 Not Cancer Driver No 1 intact, hippie 68 5 4 4 0
RGS7_ENST00000366563 RGS7 P49802 Regulator of G-protein signaling 7 chr1 Census, Compendium Yes 1 hippie 196 150 50 50 0
SEPT3 SEPTIN3 Q9UH03 Neuronal-specific septin-3 chr22 Not Cancer Driver No 1 intact 51 105 13 13 0
SET SET Q01105 Protein SET chr9 Census, Compendium Yes 1 hippie 35 221 26 26 2
SGSM3 SGSM3 Q96HU1 Small G protein signaling modulator 3 chr22 Not Cancer Driver No 1 intact, hippie 83 77 9 9 0
SLC4A7_ENST00000295736 SLC4A7 Q9Y6M7 Sodium bicarbonate cotransporter 3 chr3 Not Cancer Driver No 2 hippie, biogrid 165 406 57 57 0
STARD3 STARD3 Q14849 StAR-related lipid transfer protein 3 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 51 34 6 6 0
STX18 STX18 Q9P2W9 Syntaxin-18 chr4 Not Cancer Driver No 2 hippie, biogrid 28 174 15 15 0
TAP1 TAP1 Q03518-2 Isoform 2 of Antigen peptide transporter 1 chr6 Not Cancer Driver No 1 hippie 67 83 6 6 0
TELO2 TELO2 Q9Y4R8 Telomere length regulation protein TEL2 homolog chr16 Not Cancer Driver No 1 intact, hippie, biogrid 113 154 23 23 5
TPM3 TPM3 P06753 Tropomyosin alpha-3 chain chr1 Census Yes 1 intact, hippie 35 230 27 27 21
TTI1 TTI1 O43156 TELO2-interacting protein 1 homolog chr20 Not Cancer Driver No 2 intact, hippie, biogrid 136 93 13 13 0
TUBA3C TUBA3C P0DPH7 Tubulin alpha-3C chain chr13 Not Cancer Driver No 2 biogrid 185 36 14 14 0
TUBA3D TUBA3D P0DPH8 Tubulin alpha-3D chain chr2 Not Cancer Driver No 1 hippie 74 36 4 4 0
TUBA4A TUBA4A P68366 Tubulin alpha-4A chain chr2 Not Cancer Driver No 2 intact, hippie, biogrid 73 39 4 4 5
TUBB3 TUBB3 Q13509 Tubulin beta-3 chain chr16 Not Cancer Driver No 1 intact, hippie, biogrid 67 53 10 10 12
TUBB8 TUBB8 Q3ZCM7 Tubulin beta-8 chain chr10 Not Cancer Driver No 1 intact, hippie, biogrid 103 53 18 18 13
USP46 USP46 P62068 Ubiquitin carboxyl-terminal hydrolase 46 chr4 Not Cancer Driver No 2 intact, hippie, biogrid 48 28 4 4 0
YIPF3 YIPF3 Q9GZM5 Protein YIPF3 chr6 Not Cancer Driver No 1 hippie 38 87 13 13 0
YIPF4 YIPF4 Q9BSR8 Protein YIPF4 chr2 Not Cancer Driver No 1 hippie, biogrid 25 22 1 1 0