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CGN ,CGN ,Q9P2M7
  • Uniprot Accession= Q9P2M7
  • Ensembl Transcript= ENST00000271636.11
  • Uniprot Name= CGN
  • Name= Cingulin
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 60
  • Number of Interaction partner in biogrid: 29
  • Number of Interaction partner in hippie: 134
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTA2 ACTA2 P62736 Actin, aortic smooth muscle chr10 Not Cancer Driver No 2 hippie, biogrid 50 39 4 4 17
AFDN_ENST00000447894 AFDN P55196 Afadin chr6 Census Yes 1 hippie 248 1247 180 180 0
AGAP1 AGAP1 Q9UPQ3 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 chr2 Not Cancer Driver No 1 hippie 163 403 81 81 0
AMOT AMOT Q4VCS5 Angiomotin chrX Not Cancer Driver No 1 hippie, biogrid 161 909 128 128 0
ANLN ANLN Q9NQW6 Anillin chr7 Not Cancer Driver No 1 hippie 144 767 104 104 2
AR AR P10275 Androgen receptor chrX Census, Compendium Yes 1 hippie 196 443 88 88 169
ARHGEF11_ENST00000361409 ARHGEF11 O15085 Rho guanine nucleotide exchange factor 11 chr1 Not Cancer Driver No 1 hippie, biogrid 213 1036 138 138 0
ARHGEF2 ARHGEF2 Q92974 Rho guanine nucleotide exchange factor 2 chr1 Not Cancer Driver No 1 hippie 146 450 70 70 0
CAMSAP2 CAMSAP2 Q08AD1 Calmodulin-regulated spectrin-associated protein 2 chr1 Not Cancer Driver No 1 hippie 176 1025 127 127 0
CAPZA2 CAPZA2 P47755 F-actin-capping protein subunit alpha-2 chr7 Not Cancer Driver No 1 hippie 37 19 0 0 0
CBY1_ENST00000216029 CBY1 Q9Y3M2 Protein chibby homolog 1 chr22 Not Cancer Driver No 2 intact, hippie 13 98 11 11 0
CCDC102B CCDC102B Q68D86 Coiled-coil domain-containing protein 102B chr18 Not Cancer Driver No 1 hippie, biogrid 133 334 89 89 0
CCDC8 CCDC8 Q9H0W5 Coiled-coil domain-containing protein 8 chr19 Not Cancer Driver No 1 hippie 96 505 91 91 0
CDC25B CDC25B P30305 M-phase inducer phosphatase 2 chr20 Not Cancer Driver No 1 hippie 80 328 43 43 0
CDC25C CDC25C P30307 M-phase inducer phosphatase 3 chr5 Not Cancer Driver No 2 intact, hippie 61 224 26 26 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 39 23 2 2 1
CDH1 CDH1 P12830 Cadherin-1 chr16 Census, Compendium Yes 1 hippie 150 400 82 82 5
CDK16_ENST00000357227 CDK16 Q00536 Cyclin-dependent kinase 16 chrX Not Cancer Driver No 1 hippie 55 139 30 30 0
CDKL2_ENST00000429927 CDKL2 Q92772 Cyclin-dependent kinase-like 2 chr4 Not Cancer Driver No 1 intact, hippie, biogrid 63 171 21 21 0
CEP135 CEP135 Q66GS9 Centrosomal protein of 135 kDa chr4 Not Cancer Driver No 1 hippie, biogrid 127 690 72 72 0
CRTC2 CRTC2 Q53ET0 CREB-regulated transcription coactivator 2 chr1 Not Cancer Driver No 1 hippie 92 674 88 88 0
CRTC3 CRTC3 Q6UUV7 CREB-regulated transcription coactivator 3 chr15 Census Yes 2 intact, hippie 70 608 68 68 0
CSNK1A1_ENST00000377843 CSNK1A1 P48729 Casein kinase I isoform alpha chr5 Not Cancer Driver No 2 intact, hippie 44 46 3 3 0
CTNNA1 CTNNA1 P35221 Catenin alpha-1 chr5 Census Yes 1 hippie, biogrid 126 268 35 35 4
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 Not Cancer Driver No 2 intact, hippie, biogrid 131 681 68 68 0
DBN1_ENST00000309007 DBN1 Q16643 Drebrin chr5 Not Cancer Driver No 1 intact, hippie 84 510 73 73 0
DCLK1 DCLK1 O15075 Serine/threonine-protein kinase DCLK1 chr13 Not Cancer Driver No 1 hippie 209 252 77 77 0
DCP1B DCP1B Q8IZD4 mRNA-decapping enzyme 1B chr12 Not Cancer Driver No 2 intact, hippie 82 406 63 63 0
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 Not Cancer Driver No 1 hippie 118 61 10 10 2
DENND1A DENND1A Q8TEH3 DENN domain-containing protein 1A chr9 Not Cancer Driver No 1 hippie 117 589 76 76 0
DENND4A_ENST00000431932 DENND4A Q7Z401 C-myc promoter-binding protein chr15 Not Cancer Driver No 1 hippie 199 570 64 64 0
DENND4C_ENST00000602925 DENND4C Q5VZ89 DENN domain-containing protein 4C chr9 Not Cancer Driver No 2 intact, hippie 190 710 69 69 0
DLST DLST P36957 Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial chr14 Not Cancer Driver No 1 intact, hippie, biogrid 53 190 32 32 1
EIF4E2 EIF4E2 O60573 Eukaryotic translation initiation factor 4E type 2 chr2 Not Cancer Driver No 2 intact, hippie 27 80 5 5 0
ERLEC1 ERLEC1 Q96DZ1 Endoplasmic reticulum lectin 1 chr2 Not Cancer Driver No 1 hippie, biogrid 54 134 17 17 0
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 intact, hippie 90 92 11 11 1
EYA2 EYA2 O00167 Eyes absent homolog 2 chr20 Not Cancer Driver No 1 intact, hippie 107 204 50 50 0
F11R F11R Q9Y624 Junctional adhesion molecule A chr1 Not Cancer Driver No 1 hippie 47 72 15 15 0
FBXL13_ENST00000436908 FBXL13 Q8NEE6 Dynein regulatory complex subunit 6 chr7 Not Cancer Driver No 1 hippie 103 41 5 5 0
FGD6 FGD6 Q6ZV73 FYVE, RhoGEF and PH domain-containing protein 6 chr12 Not Cancer Driver No 2 intact, hippie 198 804 117 117 0
GAB2 GAB2 Q9UQC2 GRB2-associated-binding protein 2 chr11 Not Cancer Driver No 1 hippie 85 537 73 73 0
GIGYF1_ENST00000646601 GIGYF1 O75420 GRB10-interacting GYF protein 1 chr7 Not Cancer Driver No 1 hippie 138 857 115 115 0
GIGYF2_ENST00000409547 GIGYF2 Q6Y7W6 GRB10-interacting GYF protein 2 chr2 Not Cancer Driver No 1 hippie 176 1096 158 158 6
HDAC4 HDAC4 P56524 Histone deacetylase 4 chr2 Not Cancer Driver No 2 intact, hippie 182 749 132 132 0
HDAC5_ENST00000586802 HDAC5 Q9UQL6 Histone deacetylase 5 chr17 Not Cancer Driver No 1 hippie 118 718 73 73 0
HDAC7_ENST00000427332 HDAC7 Q8WUI4 Histone deacetylase 7 chr12 Not Cancer Driver No 1 hippie 91 570 50 50 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 Not Cancer Driver No 1 intact, hippie 25 203 20 20 0
HOOK3 HOOK3 Q86VS8 Protein Hook homolog 3 chr8 Census Yes 1 hippie 79 493 55 55 0
IFT57 IFT57 Q9NWB7 Intraflagellar transport protein 57 homolog chr3 Not Cancer Driver No 1 hippie 46 219 18 18 0
IL13 IL13 P35225 Interleukin-13 chr5 Not Cancer Driver No 1 hippie, biogrid 20 0 0 0 0
INPP5E INPP5E Q9NRR6 Phosphatidylinositol polyphosphate 5-phosphatase type IV chr9 Not Cancer Driver No 2 intact, hippie 43 272 16 16 15
IQGAP1 IQGAP1 P46940 Ras GTPase-activating-like protein IQGAP1 chr15 Not Cancer Driver No 1 intact, hippie 183 351 35 35 0
KCTD3 KCTD3 Q9Y597 BTB/POZ domain-containing protein KCTD3 chr1 Not Cancer Driver No 2 intact, hippie 113 324 45 45 0
KIF13B KIF13B Q9NQT8 Kinesin-like protein KIF13B chr8 Not Cancer Driver No 1 hippie 187 968 82 82 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
KIF1B_ENST00000377086 KIF1B O60333 Kinesin-like protein KIF1B chr1 Not Cancer Driver No 2 intact, hippie 253 633 106 106 1
KIF1C KIF1C O43896 Kinesin-like protein KIF1C chr17 Not Cancer Driver No 2 intact, hippie 131 695 94 94 1
KIF20A KIF20A O95235 Kinesin-like protein KIF20A chr5 Not Cancer Driver No 1 hippie 79 340 40 40 1
KRT27 KRT27 Q7Z3Y8 Keratin, type I cytoskeletal 27 chr17 Not Cancer Driver No 1 hippie, biogrid 80 142 28 28 0
KSR1_ENST00000644974 KSR1 Q8IVT5 Kinase suppressor of Ras 1 chr17 Not Cancer Driver No 2 intact, hippie 114 404 58 58 0
L1TD1 L1TD1 Q5T7N2 LINE-1 type transposase domain-containing protein 1 chr1 Not Cancer Driver No 1 intact, hippie 149 534 114 114 0
LARP1 LARP1 Q6PKG0-3 Isoform 2 of La-related protein 1 chr5 Not Cancer Driver No 1 hippie 136 726 100 100 0
LATS1 LATS1 O95835 Serine/threonine-protein kinase LATS1 chr6 Census, Compendium Yes 2 hippie, biogrid 161 788 100 100 0
LATS2 LATS2 Q9NRM7 Serine/threonine-protein kinase LATS2 chr13 Census, Compendium Yes 1 hippie, biogrid 178 687 116 116 0
LIMA1_ENST00000341247 LIMA1 Q9UHB6 LIM domain and actin-binding protein 1 chr12 Not Cancer Driver No 1 hippie 88 687 81 81 0
LNX1 LNX1 Q8TBB1 E3 ubiquitin-protein ligase LNX chr4 Not Cancer Driver No 1 hippie 117 261 40 40 0
LPIN3_ENST00000373257 LPIN3 Q9BQK8 Phosphatidate phosphatase LPIN3 chr20 Not Cancer Driver No 2 intact, hippie 91 472 50 50 0
LRFN1 LRFN1 Q9P244 Leucine-rich repeat and fibronectin type III domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 96 278 37 37 0
LZTS2 LZTS2 Q9BRK4 Leucine zipper putative tumor suppressor 2 chr10 Not Cancer Driver No 1 hippie 78 508 66 66 0
MAGI1 MAGI1 Q96QZ7 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 chr3 Not Cancer Driver No 2 intact, hippie 260 1212 220 220 0
MAP3K21 MAP3K21 Q5TCX8 Mitogen-activated protein kinase kinase kinase 21 chr1 Not Cancer Driver No 2 intact, hippie 191 658 112 112 0
MAPKAP1 MAPKAP1 Q9BPZ7 Target of rapamycin complex 2 subunit MAPKAP1 chr9 Not Cancer Driver No 1 hippie 70 173 25 25 0
MAST3 MAST3 O60307 Microtubule-associated serine/threonine-protein kinase 3 chr19 Not Cancer Driver No 2 intact, hippie 169 783 100 100 0
MELK MELK Q14680 Maternal embryonic leucine zipper kinase chr9 Not Cancer Driver No 1 hippie 76 162 24 24 0
MICALL1 MICALL1 Q8N3F8 MICAL-like protein 1 chr22 Not Cancer Driver No 2 intact, hippie 90 630 72 72 0
MTFR1L_ENST00000374303 MTFR1L Q9H019 Mitochondrial fission regulator 1-like chr1 Not Cancer Driver No 2 intact, hippie 25 108 10 10 0
MTMR10 MTMR10 Q9NXD2 Myotubularin-related protein 10 chr15 Not Cancer Driver No 1 hippie, biogrid 79 98 7 7 0
MYH11_ENST00000300036 MYH11 P35749 Myosin-11 chr16 Census, Compendium Yes 1 hippie 353 1180 201 201 2
MYO18A MYO18A Q92614 Unconventional myosin-XVIIIa chr17 Not Cancer Driver No 1 hippie 268 1237 176 176 0
MYO5C MYO5C Q9NQX4 Unconventional myosin-Vc chr15 Not Cancer Driver No 1 intact, hippie 204 394 43 43 0
NADK_ENST00000341991 NADK O95544 NAD kinase chr1 Not Cancer Driver No 1 hippie 59 91 18 18 0
NAV1 NAV1 Q8NEY1 Neuron navigator 1 chr1 Not Cancer Driver No 1 intact 225 1455 167 167 0
NF1 NF1 P21359 Neurofibromin chr17 Census, Compendium Yes 2 intact, hippie 375 406 47 47 85
NPRL2 NPRL2 Q8WTW4 GATOR complex protein NPRL2 chr3 Compendium Yes 1 hippie 37 10 3 3 1
OBSL1 OBSL1 O75147 Obscurin-like protein 1 chr2 Not Cancer Driver No 1 hippie 233 553 60 60 0
OCLN OCLN Q16625 Occludin chr5 Not Cancer Driver No 1 biogrid 54 244 21 21 1
OSBPL6_ENST00000190611 OSBPL6 Q9BZF3 Oxysterol-binding protein-related protein 6 chr2 Not Cancer Driver No 2 intact, hippie 167 365 72 72 0
PANK2 PANK2 Q9BZ23 Pantothenate kinase 2, mitochondrial chr20 Not Cancer Driver No 2 intact, hippie 46 206 14 14 30
PHLDB2 PHLDB2 Q86SQ0 Pleckstrin homology-like domain family B member 2 chr3 Not Cancer Driver No 1 hippie 235 1030 190 190 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 Not Cancer Driver No 1 hippie 57 99 13 13 23
PLEKHA7 PLEKHA7 Q6IQ23 Pleckstrin homology domain-containing family A member 7 chr11 Not Cancer Driver No 3 intact, hippie 152 919 121 121 0
PPM1H PPM1H Q9ULR3 Protein phosphatase 1H chr12 Not Cancer Driver No 1 hippie 71 140 23 23 0
PPP1R13B PPP1R13B Q96KQ4 Apoptosis-stimulating of p53 protein 1 chr14 Not Cancer Driver No 1 intact, hippie 115 821 92 92 0
PPP1R9A_ENST00000433881 PPP1R9A Q9ULJ8 Neurabin-1 chr7 Not Cancer Driver No 2 intact, hippie, biogrid 217 887 174 174 0
PTPN13_ENST00000411767 PTPN13 Q12923 Tyrosine-protein phosphatase non-receptor type 13 chr4 Census, Compendium Yes 2 intact, hippie 299 1231 149 149 0
PTPN14 PTPN14 Q15678 Tyrosine-protein phosphatase non-receptor type 14 chr1 Compendium Yes 1 hippie 173 582 99 99 0
RAB11FIP2_ENST00000355624 RAB11FIP2 Q7L804 Rab11 family-interacting protein 2 chr10 Not Cancer Driver No 1 hippie 66 356 43 43 0
RALGPS2 RALGPS2 Q86X27 Ras-specific guanine nucleotide-releasing factor RalGPS2 chr1 Not Cancer Driver No 2 intact, hippie 83 183 23 23 0
RASAL2_ENST00000462775 RASAL2 Q9UJF2 Ras GTPase-activating protein nGAP chr1 Not Cancer Driver No 2 intact, hippie 164 606 86 86 0
RPTOR RPTOR Q8N122 Regulatory-associated protein of mTOR chr17 Not Cancer Driver No 1 hippie 176 241 21 21 0
RTKN RTKN Q9BST9 Rhotekin chr2 Not Cancer Driver No 1 hippie 67 265 35 35 0
SASS6 SASS6 Q6UVJ0 Spindle assembly abnormal protein 6 homolog chr1 Not Cancer Driver No 1 hippie, biogrid 82 331 37 37 1
SFN SFN P31947 14-3-3 protein sigma chr1 Not Cancer Driver No 1 hippie 27 75 9 9 0
SH3PXD2A_ENST00000369774 SH3PXD2A Q5TCZ1 SH3 and PX domain-containing protein 2A chr10 Not Cancer Driver No 1 hippie 141 797 101 101 0
SH3RF3 SH3RF3 Q8TEJ3 E3 ubiquitin-protein ligase SH3RF3 chr2 Not Cancer Driver No 1 hippie 98 564 53 53 0
SIPA1L1 SIPA1L1 O43166 Signal-induced proliferation-associated 1-like protein 1 chr14 Not Cancer Driver No 2 intact, hippie 321 1175 226 226 0
SIRT7 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 Not Cancer Driver No 1 hippie 48 163 15 15 0
SLC39A3 SLC39A3 Q9BRY0 Zinc transporter ZIP3 chr19 Not Cancer Driver No 1 hippie, biogrid 41 0 0 0 0
SRGAP2 SRGAP2 O75044 SLIT-ROBO Rho GTPase-activating protein 2 chr1 Not Cancer Driver No 1 hippie 122 541 71 71 0
SRSF12 SRSF12 Q8WXF0 Serine/arginine-rich splicing factor 12 chr6 Not Cancer Driver No 2 intact, hippie 36 205 31 31 0
STARD13 STARD13 Q9Y3M8 StAR-related lipid transfer protein 13 chr13 Not Cancer Driver No 1 hippie 177 494 78 78 0
STIL_ENST00000360380 STIL Q15468 SCL-interrupting locus protein chr1 Census, Compendium Yes 1 hippie, biogrid 147 735 85 85 1
SYDE1 SYDE1 Q6ZW31 Rho GTPase-activating protein SYDE1 chr19 Not Cancer Driver No 2 intact, hippie 62 412 27 27 0
SYNPO SYNPO Q8N3V7 Synaptopodin chr5 Not Cancer Driver No 1 intact, hippie 103 918 102 102 0
TANC2 TANC2 Q9HCD6 Protein TANC2 chr17 Not Cancer Driver No 2 intact, hippie 278 999 127 127 1
TBC1D1 TBC1D1 Q86TI0 TBC1 domain family member 1 chr4 Not Cancer Driver No 2 intact, hippie 138 455 58 58 0
TESK2 TESK2 Q96S53 Dual specificity testis-specific protein kinase 2 chr1 Not Cancer Driver No 2 intact, hippie 77 242 43 43 0
TIAF1 MYO18A O95411 Putative TGFB1-induced anti-apoptotic factor 1 chr17 Not Cancer Driver No 1 hippie 16 30 5 5 0
TIAM1 TIAM1 Q13009 Rho guanine nucleotide exchange factor TIAM1 chr21 Not Cancer Driver No 2 intact, hippie 370 810 194 194 0
TJP1_ENST00000346128 TJP1 Q07157 Tight junction protein ZO-1 chr15 Not Cancer Driver No 4 intact, hippie, biogrid 198 1350 151 151 0
TJP2_ENST00000377245 TJP2 Q9UDY2 Tight junction protein ZO-2 chr9 Not Cancer Driver No 2 hippie, biogrid 149 919 113 113 1
TMEM147 TMEM147 Q9BVK8 Transmembrane protein 147 chr19 Not Cancer Driver No 1 hippie, biogrid 23 0 0 0 0
TNKS TNKS O95271 Poly [ADP-ribose] polymerase tankyrase-1 chr8 Not Cancer Driver No 1 intact 163 480 59 59 0
TP53BP2 TP53BP2 Q13625 Apoptosis-stimulating of p53 protein 2 chr1 Not Cancer Driver No 1 intact, hippie 152 868 118 118 0
TPR TPR P12270 Nucleoprotein TPR chr1 Census Yes 1 hippie 311 1990 266 266 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
USP14 USP14 P54578 Ubiquitin carboxyl-terminal hydrolase 14 chr18 Not Cancer Driver No 1 hippie 59 86 6 6 0
WEE1 WEE1 P30291 Wee1-like protein kinase chr11 Not Cancer Driver No 2 intact, hippie 60 399 27 27 0
YWHAB_ENST00000353703 YWHAB P31946 14-3-3 protein beta/alpha chr20 Not Cancer Driver No 3 intact, hippie, biogrid 22 109 4 4 0
YWHAE YWHAE P62258 14-3-3 protein epsilon chr17 Census Yes 3 intact, hippie, biogrid 32 41 3 3 0
YWHAG YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 4 intact, hippie, biogrid 26 77 9 9 2
YWHAH YWHAH Q04917 14-3-3 protein eta chr22 Not Cancer Driver No 2 intact, hippie, biogrid 15 55 3 3 0
YWHAQ YWHAQ P27348 14-3-3 protein theta chr2 Not Cancer Driver No 2 intact, hippie, biogrid 29 41 6 6 0
YWHAZ_ENST00000395956 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 3 intact, hippie, biogrid 30 81 10 10 0
ZBTB21 ZBTB21 Q9ULJ3 Zinc finger and BTB domain-containing protein 21 chr21 Not Cancer Driver No 2 intact, hippie 136 645 75 75 0
ZDHHC5 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 Not Cancer Driver No 1 hippie 89 462 63 63 0
ZNF638 ZNF638 Q14966 Zinc finger protein 638 chr2 Not Cancer Driver No 2 intact, hippie 243 1667 209 209 0